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Open Access Article
1 - Contamination of brucellosis in milk and cheese by Real time PCR
fatemeh Khodaverdipour Nazila Arbab Soleimani Yasaman BorounBrucella spp are small, immobile, gram-negative bacteria that are lacking capsules and formed like cocobacillus. Brucellosis is a zoonosis infection between humans and animals that can lead to miscarriages, fertility disorders, genital infections, reduction in milk pro MoreBrucella spp are small, immobile, gram-negative bacteria that are lacking capsules and formed like cocobacillus. Brucellosis is a zoonosis infection between humans and animals that can lead to miscarriages, fertility disorders, genital infections, reduction in milk production, urethritis, and epididymitis in the original host, resulting in many medical disorders in patients and unnecessary treatment expenses. Moreover, farmers would end up facing significant economic losses. Despite advances in blood culture techniques and serological tests to detect specific antibiotics, there are still significant difficulties in the diagnosis of brucellosis; therefore, a new laboratory test is needed for a better examination. One of the most recent quantitative methods that have already caught the attention of many researchers is the detection of bacteria by Real Time PCR method. The aim of this study is to identify bacteria of the genus Brucella, both in milk and cheese samples, by the method of Real Time PCR. 25 samples of cow's milk and twenty-five samples of cheese were collected from different parts of Shahrekord city. DNA extraction was performed using the DNA extraction kit (Cinnagen company) for the molecular diagnosis. Then, by the use of Real Time PCR reaction (Corbett Rotor-Gene Model, manufactured in Australia), samples were studied. In this study, fifty samples were examined, and only two samples (4%) were diagnosed with Brucella abortus, meanwhile, there were no reports on infections by Brucella in the cheese samples. Conclusion: This study shows that molecular techniques such as Real Time PCR can be used as a complementary method for the detection of Brucella, alongside all the other common methods. Manuscript profile -
Open Access Article
2 - Contamination of brucellosis in blood samples of seropositive patients for Brucella in the Shahr-e Kord and Isfahan city by Real Time PCR method
Hossein Khodabandeh shahraki nazila Arbab SoleimaniBrucellosis is one of the most common bacterial diseases in both humans and animals.It causes human to suffer from Malta fever and has highly economic losses in livestock. Bacteriological culture and serological tests for the diagnosis of chronic cases are insensitive. MoreBrucellosis is one of the most common bacterial diseases in both humans and animals.It causes human to suffer from Malta fever and has highly economic losses in livestock. Bacteriological culture and serological tests for the diagnosis of chronic cases are insensitive. Therefore, the use of Real Time PCR is a great help to evaluate the frequency of types of brucella abortus and brucella melitensis in serum of people with positive serology. Serum samples of 30 cases with right positive test (over 1/160) were collected from DNA clinical laboratories in the cities of Shahrekord and Esfahan and they were extracted with the use of signagen DNA extraction kit. In order to identify the genus and the types of brucella abortus and brucella melitensis Real Time PCR reaction was carried out on the samples. In this study, all 30 samples were confirmed with the use of Real Time PCR. Brucella abortus was detected in all samples in the cities of Esfahan and Shahrekord. After Real Time PCR test was run on females, brucella abortus was just detected, While in males, 22 (%73/33) cases suffered from brucella abortus and 3 (%10) suffered from brucella melitensis. From the total of 7 cases with brucellosis infection in the age group below 30 years old, 6 (%85/7) cases suffered from brucella abortus and 1 (%14/3) suffered from brucella melitensis, While from the 23 cases with brucellosis in the age group over 30 years old, 21 (% 91/3) had brucella abortus and 2 (%8/7) had brucella melitensis. In recent years many molecular methods have been used for the detection of this bacteria. Real Time PCR method in the sense that it requires less time and has high sensitivity and specificity is very useful in the diagnosis of the disease Manuscript profile -
Open Access Article
3 - Conceptualization of business excellence model: Based on future study approach
Yousof Malek Mirzaee Mohammad Mahmoudi Maymand Ali Rajabzadeh Mahmoud Samiei NasrThis is a philosophical study with critical paradigm, using symbolic interactionism with fundamental orientation, inductive reasoning, the qualitative library-based approach, the Grounded Theory, meta-synthesis and the content analysis method. It aims to describe and ex MoreThis is a philosophical study with critical paradigm, using symbolic interactionism with fundamental orientation, inductive reasoning, the qualitative library-based approach, the Grounded Theory, meta-synthesis and the content analysis method. It aims to describe and explore the business excellence model and identify its variables and indicators based on a futuristic approach. Using the meta-synthesis and meta-analysis techniques, the methods involve open, axial and selective coding, resulting in a new concept. The required data were collected through a review and study of the documents on business excellence models. The study specifically focused on the models set forth in valid magazines and journals with the theoretical sampling logic in order to reach theoretical saturation. We used two long-term and holistic participatory strategies for validity, as well as two coders with agreement on open coding for reliability. We used the MAXQDA software for data analysis. The findings of this study were obtained from 101 conceptual models of business excellence and 869 concepts or open codes at the coding stage. Then the basic codes with the same meanings were divided into 24 major categories, which led to the creation of five dimensions at the selective coding stage and a theoretical concept with the dimensions of people, market, work, management, and underlying factors. This theory made an important contribution to the success of small and medium-sized businesses by taking into account the new paradigms for assessing businesses in the future. Manuscript profile -
Open Access Article
4 - Investigating the ability to predict human resource excellence through futures study skills in ceramic tile companies of Yazd province
Amirehsan Eshaghiyeh Hossien Eslami Hadi HematianBackground:Quality human resources are the most important resource of any company and leading industries,realizing this fact,have made an indescribable effort to make optimal use of this key resource to achieve their goals.Therefore,the present study was conducted with MoreBackground:Quality human resources are the most important resource of any company and leading industries,realizing this fact,have made an indescribable effort to make optimal use of this key resource to achieve their goals.Therefore,the present study was conducted with the ability to predict human resource excellence through futures study skills in ceramic tile companies of Yazd province. Method:This research is applied in terms of purpose and is from a descriptive-correlational type.The statistical population of this study is the managers and personnel of ceramic tile companies of Yazd province,whose number is 22,000people and using Krejcie and Morgan table,at least384people were selected as a statistical sample and 390 questionnaires were collected based on an available sampling process,distribution, and data. Data collection was done by the field method and the collection tool was a researcher-made questionnaire.In data analysis,the SPSS software was used to test the hypotheses and conceptual model of the research,and the SmartPLS was used for the validity and reliability of the questionnaire.Findings:The findings showed that the correlation coefficient between futures study skills and human resource excellence as well as other dimensions of futures study and human resource excellence is significant and future study skills have25.3%of the ability to predict the human resource excellence of ceramic tiles of Yazd province.Conclusion:The managers of ceramic tile companies can achieve human resource excellence based on the past work process to identify the current changes signals of possible situations that may occur in the future,as well as to shape the desired world of tomorrow. Manuscript profile -
Open Access Article
5 - Future Scenario Planning for the Impact of Organizational Excellence on Marketing Management in Universities
Vahidreza Mirabi Nassim Heidari Jalal HaghighatmonfaredIn this study, the future scenario of the impact of organizational excellence on marketing management in the field of universities was investigated. The statistical population of this study is the participants of specialists or experts. They need sufficient knowledge an MoreIn this study, the future scenario of the impact of organizational excellence on marketing management in the field of universities was investigated. The statistical population of this study is the participants of specialists or experts. They need sufficient knowledge and experience in the subject, willingness, sufficient time to participate, and effective communication skills. Statistical sample of this research 10 industry experts have been selected for interview. Data collection tools in this research, field research includes books, articles, the Internet or any appropriate scientific source and reference of experimental findings and questions from elites and experts in related fields (interviews). After the interview, the information was analyzed. The interview analysis method is theme analysis. Team analysis is a method of determining, analyzing, and expressing patterns (themes) within data. The main themes extracted from the current research are human resources, value management and competitor identification. In the first scenario, the outlook for the next 10 years of the Azad University in Iran will not be considered very favorable if the current situation continues. With the continuation of the current trend, the share of university students is very small due to its capacities in our country. In the second scenario (rapid growth and connection with the world) it is proposed that Iran connect with the global economy by attracting more students. The third scenario is balanced growth and connection with the world. A 30% increase in student enrollment is one of the goals of this scenario. Manuscript profile -
Open Access Article
6 - Designing a of Human Resource Excellence Model in Iranian Public Sectors using the Fuzzy Delphi Technique
N. Mirsepassi A. Toloie Eshlaghy Gh. Memarzadeh M. PeidaieA literature search failed to identify a preferred definition of organizational excellence. While manyclaim to know its meaning and may indeed profess to be working towards the achievement ofexcellence, few give the same definition. Despite this, the term “excelle MoreA literature search failed to identify a preferred definition of organizational excellence. While manyclaim to know its meaning and may indeed profess to be working towards the achievement ofexcellence, few give the same definition. Despite this, the term “excellence” is widely used within thepublic sector. This problem exists more in the public sector than in other sectors and is more in HRMthan in other organizational departments.In this paper, we develop an approach based on the Fuzzy Delphi Technique (FDT) to model humanresource excellence (HRE) in the Iranian public sector. We efficiently apply the new definition ofexcellence in HRM. The HRE conceptual model is formed based on literature reviews and expertsopinions collected using FDT. The HRE model is formed on four dimensions and 57 criteria and isproposed for HRM pathology and Iranian National awards in public sectors. The proposed model hasbeen efficiently been applied on a large scale in Iran for the evaluation of existing and developing HRcapabilities Manuscript profile -
Open Access Article
7 - Presentation Model for Management By Value And Its the Impact on Organizational Excellence Islamic Azad University
Abolghasem Barimani Kiumars Niaz AzariThe aim of this study is the investigation of the presentation model for of management by value and its the impact on organizational excellence in Mazandaran Islamic Azad university.This study is objectively application AL and methodologically correlational descriptive MoreThe aim of this study is the investigation of the presentation model for of management by value and its the impact on organizational excellence in Mazandaran Islamic Azad university.This study is objectively application AL and methodologically correlational descriptive. Statistical population of this study includes all faculty members with the rank of Assistant professor Associate professor and professor. Statistical samples were 212 and selected by the use of Cochran formula and they have been chooser by random stratified sampling. We have used researcher self-made questionnaire of management by value and standard questionnaire of EFQM model. its reliability was achieved by Cronbach's Alpha formula and they were 0/98 and 0/97 respectively. In order to data analysis the resultant, The structural equation modeling With the help of partial least square method was used by statistical software PLS. The results of path coefficients showed a significant relationship between management by value and organizational excellence the variables.76/7 percent of organizational excellence has been approved by management by value. Also model fit indices indicate that the proposed model is an appropriate fit. Manuscript profile -
Open Access Article
8 - Work in an organization with full extent life ( Employment in an informational society)
GH.R. KhakiThere are many definitions about economy . According to one of the famous accepted definitions , economic laws have classified to two groups. Both of them are &nb MoreThere are many definitions about economy . According to one of the famous accepted definitions , economic laws have classified to two groups. Both of them are influenced by social structure and it’s changes so they are different in various societies . Movement from one society to another happens due to “intellectualize” , principal maximum production with minimum cost . This process continues until we enter a post industrial information society . Many wonderful changes creats in kind and form of organizations and nature of work and employment when IT grows and spreads in various levels and dimensions of human life . E- commerce is a concept that includes various compilations in new societies and the most comprehensive concept in information epoch . Surely , people must play another role in this process so the must earn abilities different from which to be successful in societies before . In any period of business history , special structures conguer in organizations depending on it’s nature . Cellular and virtual structures are under consideration in present societies due to the special particular . In this article , we point to the especialities of these two structures and explain the process of forming virtual organizations and how to select employees in these organizations completely . it’s certain that economic position of Iran influences by economic changes in the world and also effects on it . in principle , any country can’t act personally in an international level with present conditions . Now , our country has the problem of little power and high cost of investing capital and so the idea of creating virtual organization due to it’s specialities can change employment paradigm . We also study about employment position and it’s weaknesses and strengths in Iran to find a way to use strengths to solve weaknesses . Manuscript profile -
Open Access Article
9 - Celebrations and Celebratory Behaviors in the Territory of Jahāngīrshāh Gurkānī (1037-1014 AH) Based on Jahāngīrnāmih and Majālis Jahāngīrī
Hossein Tavakoli Moqadam Qanbarali RoudgarAmong the Gurkān kings of India, the long twenty-three-year reign of Jahāngīr Shah (1014-1037 AH) is especially famous because he was interested in Persian language and Iranian culture. He also wrote his diaries in Persian and named it Jahāngīrnāmih. Based on this book MoreAmong the Gurkān kings of India, the long twenty-three-year reign of Jahāngīr Shah (1014-1037 AH) is especially famous because he was interested in Persian language and Iranian culture. He also wrote his diaries in Persian and named it Jahāngīrnāmih. Based on this book of Jahāngīr Shah and the report of one of his courtiers, Abdul Sattar Lahori, that is, the book of Jahāngīrī's meetings. The authors of the following article, relying on the descriptive-analytical method and with a comparative study, have tried to hold celebrations and festive behaviors that both works have been widely explained, examined. Then answer these questions such as what were the main elements of each of the festivals of Hindus, Iranians and Muslims, and what transformations have those festivals undergone? Based on the findings of this research, fire-lighting and lighting, which were elements of Iranian and Indian celebrations, had obvious effects on most of the festive behaviors of Muslims, as sometimes some Islamic holidays, such as Shab Barat, which had entirely an Islamic content had changed into a kind of non-religious festival, so that the commemoration ceremony of Muslim parents and elders with the presence of minstrels and musicians became a festive ceremony. Manuscript profile -
Open Access Article
10 - Improved efficiency of a SiGe thin film solar cell structure using CNT charge collector layer
Homa Hashemi Madani Mohammad Reza Shayesteh Mohammad Reza Moslemi -
Open Access Article
11 - Excitation of R- and L-waves by laser propagation through over-dense magnetized plasma and their verification
Gaurav Kumar Hitendra K. Malik -
Open Access Article
12 - Analytical approach for the use of different gauges in bubble wakefield acceleration
Hitendra Malik Sonu Kumar Vidushi Dhaka Dhananjay Singh -
Open Access Article
13 - Electrical and optical parameter-based numerical simulation of high-performance CdTe, CIGS, and CZTS solar cells
Galib Hashmi Md. Shawkot Hossain Masudul Imtiaz -
Open Access Article
14 - Particle acceleration by three-dimensional asymmetric current sheet
Zahra Akbari Mahboub Hosseinpour Mohammad ali Mohammadi -
Open Access Article
15 - Numerical investigations of electron-self-injection in different shaped bubbles in wakefield acceleration
Sonu Kumar Dhananjay Singh Hitendra K. Malik -
Open Access Article
16 - Improving optical absorptivity of natural dyes for fabrication of efficient dye-sensitized solar cells
Reza Hemmatzadeh Ahmad Mohammadi -
Open Access Article
17 - Diagnostic of plasma discharge parameters in helium filled dielectric barrier discharge
Pooja Gulati Udit Narayan Pal Mahesh Kumar Ram Prakash Vishnu Srivastava Vimal Vyas -
Open Access Article
18 - Proton driven plasma wakefield generation in a parabolic plasma channel
Y. Golian D. Dorranian -
Open Access Article
19 - Effect of external applied electric field on the silicon solar cell’s thermodynamic efficiency
R. Zieba Falama Justin Mibaile E. Guemene Dountio Noël Djongyang Serge Y. Doka Timoleon C. Kofane -
Open Access Article
20 - Simulation study to find suitable dopants of CdS buffer layer for CZTS solar cell
Farjana Akter Jhuma Mohammad Junaebur Rashid -
Open Access Article
21 - Cellular polypropylene electromechanical properties: exploring the nonlinear region
Pavlos Sgardelis Michele Pozzi -
Open Access Article
22 - Depositions and characterization of sol–gel processed Al-doped ZnO (AZO) as transparent conducting oxide (TCO) for solar cell application
Afrina Sharmin Samia Tabassum M. S. Bashar Zahid Hasan Mahmood -
Open Access Article
23 - Start current and growth rate in Smith–Purcell free-electron laser with dielectric-loaded cylindrical grating
Zahra Rezaei Bizhan Farokhi -
Open Access Article
24 - Accelerating Bianchi type-VI0 bulk viscous cosmological models in Lyra geometry
A. Asgar M. Ansari -
Open Access Article
25 - Beam shaping assembly study for BNCT facility based on a 2.5 MeV proton accelerator on Li target
J. G. Fantidis -
Open Access Article
26 - Dyes extracted from Trigonella seeds as photosensitizers for dye-sensitized solar cells
Amal Batniji Monzir S. Abdel-Latif Taher M. El-Agez Sofyan A. Taya Hatem Ghamri -
Open Access Article
27 - Investigation of the impact of different ARC layers using PC1D simulation: application to crystalline silicon solar cells
Galib Hashmi Mohammad Junaebur Rashid Zahid Hasan Mahmood Mahbubul Hoq Md. Habibur Rahman -
Open Access Article
28 - Novel Defect Terminolgy Beside Evaluation And Design Fault Tolerant Logic Gates In Quantum-Dot Cellular Automata
Mehrdad Poorhosseini -
Open Access Article
29 - A New Approach to Solve N-Queen Problem with Parallel Genetic Algorithm
Monire Taheri Sarvetamin Amid Khatibi Mohammad Hadi Zahedi -
Open Access Article
30 - Robot Path Planning Using Cellular Automata and Genetic Algorithm
Zeynab Sedreh Mehdi Sadeghzadeh -
Open Access Article
31 - The Pathology of Personal Teacher Excellence, a New Model in the elite Teacher Selection Policy
meysam ghavidel bajgiran Moslem Cherabein elham fariborzi Ahmad AkbariBackground:Today, the selection of elite teacher in accordance with specific criteria and a thoughtful administrative process, But over the last few years there has been a lot of criticism. An important issue in the evaluation of teachers who have been neglected, Pay at MoreBackground:Today, the selection of elite teacher in accordance with specific criteria and a thoughtful administrative process, But over the last few years there has been a lot of criticism. An important issue in the evaluation of teachers who have been neglected, Pay attention to the teachers themselves as people who have unique characteristics. One of the most important of these is personal excellence. Objective:the present study aims to pathology of Personal excellence of teachers as a model in selecting elite teachers. Methods:the present study is qualitative and dependent on the phenomenological method. For this purpose semi-structured interviews were conducted with 19 professors of educational sciences, managers and deputies with experience and success in Khorasan Razavi province, who were selected as criterion-oriented and informants. Data were analyzed based on a seven-step Colaizzi strategy. findings: Personal excellence is a phenomenon that can be considered in choosing the elite teacher. In order to promote teachers' personal excellence, obstacles, consequences and facilitators were identified. Interviewees also referred to the role of the school administrator in promoting Personal Teacher Excellence. Conclusion: Personal excellence is a good role model in choosing elite teacher Therefore, it was necessary to remove its barriers and to facilitate its facilitators. Manuscript profile -
Open Access Article
32 - Review and analysis of the social responsibility of the media
Gholamhossien BiabaniSocial responsibility, an approach that is higher than the surrounding environment influenced by social organizations and its main purpose is to create a positive move, however small the community. For today's organizations, in addition to the core services and accessor MoreSocial responsibility, an approach that is higher than the surrounding environment influenced by social organizations and its main purpose is to create a positive move, however small the community. For today's organizations, in addition to the core services and accessories of your time and resources are devoted to charitable activities.Social responsibility issues, including issues which for years by experts and UNESCO in the field of media development have been raised with an emphasis on news.Accordingly, different media have the right to criticize and challenge Azsazmanhay but also against the interests and needs of society are responsible and should be held accountable.Media as the most influential cultural institutions can effectively promote the rule of law and the fight against illegality and failed to act.Today marks the freedom of expression in the media are tightly Vsngry thoughts for the rights of people and citizens and it awakened a sense of responsibility and community and government organizations will meet.for the benefit of society and the system will not lead to self-censorship and lack of public information.We unlawful pressure on the media and media Namsadkrdn space activities, for the benefit of society and the system will not lead to self-censorship and lack of public information. Manuscript profile -
Open Access Article
33 - Market-in Sima strategy to improve the quality and control production costs
Hassan Khojasteh BagherzadehIRIB can be one of the largest media organizations know that a large number of network radio and television, domestic and international vast majority of different stages of production and distribution, including the activities of the hardware or software directly respon MoreIRIB can be one of the largest media organizations know that a large number of network radio and television, domestic and international vast majority of different stages of production and distribution, including the activities of the hardware or software directly responsible is significant. This paper seeks to answer the question of whether the market and its functions for IRIB that are not among media organizations oriented in common parlance it is not their fees directly from the audience receives useful and efficient? Is it possible there and make it happen? Asked by library studies and studies and experiences achieved suggested shows that the conditions and opportunities for exceptional new with a little boost television network IRIB Physics More is made to the capacity of the periphery of the capacity of substance market, and the "market-" in the collection and provincial television networks, benefit from this situation properly. This article examines the development of trade to prompt five important step market-with what the prompt value chain, the status of market-model Five Forces Porter and functions of the market-state media presentation, and then to market requirements and to drive the market in the organization Broadcasting and assign important tasks to create a sustainable market-referenced and in the end stage for theatrical productions, as well as market-the market-operation of studio and technical facilities of the organization expressed. Manuscript profile -
Open Access Article
34 - An intelligent adaptive skin from a biomimetic approach for energy consumption reduction
hossein mahyari Afsaneh Zarkesh Mohammadjavad MahdavinejadAbstractOne of the challenges facing human beings today is the excessive consumption of fossil fuels, which has led to the depletion of non-renewable energy sources and greenhouse gas emissions, as well as global warming and climate change. This challenge has led to the MoreAbstractOne of the challenges facing human beings today is the excessive consumption of fossil fuels, which has led to the depletion of non-renewable energy sources and greenhouse gas emissions, as well as global warming and climate change. This challenge has led to the search for solutions to reduce fossil fuel consumption, such as optimizing and reducing energy consumption and the use of renewable energy. One of the most important areas of energy consumption is man-made in the field of architecture. On the other hand, one of the most important parts of a building that interacts with the outside environment is its outer skin. In this study, the need to pay attention to the outer skin of the building, as one of the most important parts that can manage and control the amount of energy consumption in a building, has been addressed. Its purpose is to achieve appropriate and effective solutions to reduce energy consumption in the building by the adaptive skin. One of the sources of modeling is the study of the process of reaction of living organisms to their external conditions. In this research, general solutions to reduce building consumption in the field of outer skin as well as the convergence of challenges of a building skin and mechanisms in nature for survival are discussed. It can be said that one of the most similar living organisms to adapt behavior to the facade and skin of a building are plants. Because while they do not have much mobility, they have to manage their challenges such as receiving sunlight. By modeling plants, the challenges of using and protecting sunlight in the building can be managed. The method of collecting information and data from libraries and Internet sites and the research method is descriptive-analytical and simulation using simulation software and measuring its efficiency in controlling the entry of sunlight into the inside by climate analysis and light analysis software. By modeling the behavior of a special type of plant called Oxalis oregano and abstracting from it, a concept has been reached whose structural principles have been simulated by GrassHopper plugin in Rhino software 6. This module can be generalized on the facade and can control the amount of sunlight entering the building mass by opening and closing it. Transparent photovoltaic cells (TPV) are used in the body of the module, which in addition to providing energy for opening and closing the modules, does not impede visual vision. Examining the effect of the outer skin on the simulated space, it was found that these skins reduce the total heat load by 28%, reduce cooling load by 56% and the probability of glare from daylight by 23%. By modeling plants due to their static nature and adaptability to their surroundings, a mechanism in the building such as responsive skin can be achieved that control the impact of environmental variables such as sunlight into the building and thus provide visual comfort to residents in the glare of daylight reduced the use of building cooling energy. Manuscript profile -
Open Access Article
35 - Investigating antitumorigenic effects of Vaccinium arctostaphylos on colorectal cancer cells
Fatemeh Karami Mahsa Shahnazari Asa Ebrahimi Mahmood Khosrowchahli -
Open Access Article
36 - Microbial methods effect on adsorption and reduction of Aflatoxin contamination in milk
Fatemeh Rahmani Azita Faraki -
Open Access Article
37 - The effect of Lactobacillus casei derived extracellular vesicles on the expression of Toll-like receptor-2 gene
Maryam Ebrahimi Vargoorani Mohammad Hossein Modarressi Elahe Motevaseli Farzam Vaziri Seyed Davar Siadat -
Open Access Article
38 - Primary evidence on the potential of Lactobacillus paracasei in treatment of hepatocellular carcinoma
Maryam Aminaei Fatemeh Karami Mohsen Marvibaigi Fattah Sotoodehnejadnematalahi Maryam Tajabadi Ebrahimi -
Open Access Article
39 - On nicely distance-balanced of folded cube graphs
Seyedeh Maryam Hosseini pour Freydoon Rahbarnia Mehdi Alaeiyan Ahmad ErfanianA nontrivial graph is called nicely distance-balanced (nicely edge distance-balanced), whenever there exist positive integers γ_V (γ_E), such that for any adjacent vertices u and v in V(Γ), there are exactly γ_V vertices in V(Γ) (γ_E MoreA nontrivial graph is called nicely distance-balanced (nicely edge distance-balanced), whenever there exist positive integers γ_V (γ_E), such that for any adjacent vertices u and v in V(Γ), there are exactly γ_V vertices in V(Γ) (γ_E edges in E(Γ) that are closer to u than v, and exactly γ_V vertices in V(Γ) (γ_E edges in E(Γ)) that are closer to v than u. In this paper, we will prove that hyper cube Q_n and the folded cube F_n are nicely distance-balanced and Q_n is also nicely edge distance-balanced.A nontrivial graph is called nicely distance-balanced (nicely edge distance-balanced), whenever there exist positive integers γ_V (γ_E), such that for any adjacent vertices u and v in V(Γ), there are exactly γ_V vertices in V(Γ) (γ_E edges in E(Γ) that are closer to u than v, and exactly γ_V vertices in V(Γ) (γ_E edges in E(Γ)) that are closer to v than u. In this paper, we will prove that hyper cube Q_n and the folded cube F_n are nicely distance-balanced and Q_n is also nicely edge distance-balanced. Manuscript profile -
Open Access Article
40 - Base station selection in two-tier femtocell networks: A game-theoretic approach
Azadeh Pourkabirian Mehdi Dehghan Takht Fooladi Esmaeil Zeinali Amir Masoud RahmaniResource allocation has always been one of the main challenges in the design of wireless cellular networks. Suitable resource allocation, more specifically that includes suitable base station selection and bandwidth allocation can play an effective role in interference MoreResource allocation has always been one of the main challenges in the design of wireless cellular networks. Suitable resource allocation, more specifically that includes suitable base station selection and bandwidth allocation can play an effective role in interference mitigation and users’ quality of service requirement satisfaction. In this paper, a game theoretic approach is proposed to solve the BS selection problem in two-tier wireless femtocell networks. We formulate the competitive behavior of users as evolutionary game theory. We calculate the probability of a user choosing a BS, compute the cell load of each BS, and analyze the demand rejection probability of the user associated with the BS. The proposed approach maximizes network throughput as well as meeting the QoS requirements of the users. Finally, we propose a decentralized learning algorithm based on EXP3 algorithm to achieve the evolutionary equilibrium as the solution of the game. Simulation results show that the proposed approach achieves a desirable performance and guarantees users’ QoS requirements. Manuscript profile -
Open Access Article
41 - Bi-objective mathematical modeling for a green last-mile transportation network with an automated parcel locker
Amir-Hossein Zahedi-Anaraki Reza Tavakkoli-Moghaddam Ramin SadeghianThe purpose of this paper is to introduce a more integrated and specialized approach to address the challenging issues known as the "Last-Mile Transportation" and to provide a conceptual-mathematical framework for making a synergy and integration between theoretical con MoreThe purpose of this paper is to introduce a more integrated and specialized approach to address the challenging issues known as the "Last-Mile Transportation" and to provide a conceptual-mathematical framework for making a synergy and integration between theoretical concepts and classic urban logistics optimization issues. This is a two-echelon routing-location network consisting of an urban distributor (or warehouse), customers and potential locations to install two types of facilities (automated parcel locker and micro-distributor). After ordering based on their desirability, customers are able to receive their product at the door or at 24-hour parcel locker. A modified Bender decomposition algorithm is used to solve the proposed model, which is amplified by the strategy of rounding of master problem’s variables and local search. To prove the efficiency, we compared the properties obtained from the proposed algorithm with the results obtained from the epsilon-constraint method in the Python software environment, the CPLEX library and ILOG CPLEX Optimization Studio and the results confirms the absolute dominance of this method in large-sized instances. The results of the sensitivity analysis of the role of automated parcel lockers on the network’s cost and produced pollution indicate the efficiency and validity of the proposed model. Manuscript profile -
Open Access Article
42 - Financial accelerator in a DSGE model with financial and banking sectors for Iran
Hassan Heidari Ahmad MolabahramiThis study examines the financial accelerator theory of Bernanke and et al (1999) for Iran economy using a Dynamic Stochastic General Equilibrium (DSGE) model. In this regard, a DSGE model with financial and banking sectors in the New Keynesian framework is designed, ca MoreThis study examines the financial accelerator theory of Bernanke and et al (1999) for Iran economy using a Dynamic Stochastic General Equilibrium (DSGE) model. In this regard, a DSGE model with financial and banking sectors in the New Keynesian framework is designed, calibrated and simulated and the results are compared with standard DSGE model without financial sector for the quarterly data of Iran during 1371 to 1390. To examine the financial accelerator theory, the impulse responses functions of proposed model are compared with standard model. The results show that, the proposed model has better ability to fit the Economy of Iran than the standard model. The impulse responses functions analysis show that the impact of deposit rate shock on the real sector variables within the proposed model is greater and more persistence and need more time to settlement than standard model. So the theory of financial accelerator is accepted in the Economy of Iran. Manuscript profile -
Open Access Article
43 - Evaluation of the Accelerating Factor in the Iranian Oil Nationalization Movement Based on Neil Smelser’s Reform Theory
Abbas Naeemi Jourshari Mansour Vosoughi Alireza Kaldi -
Open Access Article
44 - Electronic Banking Industry and Accountability (Case of Study: Employees of Refah Bank)
Mohammad Zaman Mohammadi Raeesi Soroush Fathi -
Open Access Article
45 - Content Analysis of Iranian Celebrity Posts with the most Followers on Instagram
Zahra Zare -
Open Access Article
46 - The Application of Cell Phones in Medical Information
Seddighe Mohammad Esmaeili Laleh Joulahi Saravi -
Open Access Article
47 - The Results of the Implementation of EFQM (European Foundation of Quality Management) of the Hospital from the Perspective of Top and Middle Managers in Chamran and Shariati Hospitals in 2013
khalil Ali Mohammadzadeh Maryam YazdanjooIntroduction: Organizations using business excellence model, compare their performance with the others and emulate the best practices of successful organizations in order to provide continuous improvement of performance. The main objective of this study was to evaluate MoreIntroduction: Organizations using business excellence model, compare their performance with the others and emulate the best practices of successful organizations in order to provide continuous improvement of performance. The main objective of this study was to evaluate the effect of organizational excellence has been implemented on the performance of hospitals. Methods: Research method is surveying descriptive. Statistical society (population) are total counted and contains 50 individuals of top and middle managers of “Sh. Chamran” and “Dr. Shariati” hospitals. Data are processed by Rev. 18 of SPSS software. Quantitative data are reported as standard deviation (±) and qualitative mean data as quantity (%). Two sample T-test was used to compare other quantitative variables and statistical significance level was considered 0.5% for tests. Results: In statistical analysis, management commitment dimension with mean and standard deviation 57.87±16.01 had maximum, and improvement in hospital results with mean and standard deviation 51.16±17.41 had minimum scores. There was a statistical significant association (P<0.001) between self assessment total scores taken from organizational excellence model and operation of two hospitals (Shariati and Chamran) Conclusion: Considering results of this study show that accomplished organizational excellence model has a positive and major effect on hospital operation; so some suggestions were recommended to population executives. Manuscript profile -
Open Access Article
48 - Analysis of the Effect of Quantum Leadership Dimensions on Organizational Excellence with the Intermediate Role of Knowledge Management and Quantum Skills in Ardabil University of Medical Sciences
Ahad Norouzzadeh Soleyman Iranzadeh Nasser Feghi FarahmandIntroduction: The main purpose of the present study is to analyze the effect of quantum leadership dimensions on organizational excellence with the mediating role of organizational knowledge management and quantum skills in Ardabil University of Medical Sciences. Metho MoreIntroduction: The main purpose of the present study is to analyze the effect of quantum leadership dimensions on organizational excellence with the mediating role of organizational knowledge management and quantum skills in Ardabil University of Medical Sciences. Methods: Questionnaire was used for data collection. The validity and reliability of the questionnaire were confirmed. The statistical population of this study was all 3569 staff of Ardabil University of Medical Sciences. 347 individuals were selected and studied according to Morgan table by simple random sampling method. Structural equation modeling methods were also used for data analysis. Results: Two hypotheses were presented for the present study that after testing the results showed that the dimensions of quantum leadership have a significant effect on organizational excellence with the mediating role of knowledge management (β=0.616). The results also showed that quantum leadership dimensions have a significant effect on organizational excellence with the mediating role of quantum skills (β=0.719). Conclusion: Considering the meaningful relation between quantum leadership and organizational excellence with mediator role of organizational knowledge management and quantum Skills in Ardabil University of medical sciences, it can be concluded that in upgrading the level of university administrators, we can improve quantum skills and strategic management of organizational knowledge. Manuscript profile -
Open Access Article
49 - Evaluating and Prioritizing Effective Factors in Selecting Celebrity Endorsements for Advertising Campaigns from the Consumers' Point of View
M. A. Abdolvand A. Hoseinzadeh EmamNowadays, the use of references group in product marketing and advertising is one of the major factors in companies' promotion strategies. Celebrities as one of the major tools in advertising can lead to encourage consumers to use specific products because of their spec MoreNowadays, the use of references group in product marketing and advertising is one of the major factors in companies' promotion strategies. Celebrities as one of the major tools in advertising can lead to encourage consumers to use specific products because of their special and unique abilities or characteristics. This study evaluate 11 factors of celebrities characteristics in order to figure out consumers believes and preferences. Finally, the factors that are effective in consumers' selection were identified and prioritized. In order to collect the required information, using questionnaire chosen 210 persons from 5 big area of Tehran ( north,south,west,east,center ) at cluster random sampling . Multiple regression with SPSS software was used for the data analysis. Study results showed that consumers' prioritizations are: celebrity popularity, multiple endorsements, celebrity-product match, celebrity credibility, celebrity physical attractiveness, celebrity-target audience, celebrity should be product user, celebrity controversy risk, previous endorsement, celebrity availability. Moreover 3 factors have significant effects that are: celebrity popularity, celebrity multiple endorsements, celebrity availability. Manuscript profile -
Open Access Article
50 - Factors Affecting Customer Retention Among Cell Phone Users
Gh. Ansariranani M. Mohamadian A. Sina Ghods,Cell phone service providers are one of the most important services industries. Considering the competitive and growing market, and the fact that the cost of gaining a new customer is much more than keeping one, understanding the elements of customer rete MoreCell phone service providers are one of the most important services industries. Considering the competitive and growing market, and the fact that the cost of gaining a new customer is much more than keeping one, understanding the elements of customer retention is essential for cell phone service providers. Based on the work of Richarme (2007), this paper presents a survey that examines the variables of customer retention, including customer satisfaction, brand switching barriers, and affect. The results are based on a survey which was conducted during the late summer and early fall of 1388 in the cell phone and SIM card trade center of Tehran. The statistical population is the people of Tehran, and the statistical sample is those who were in the aforementioned place having the intent to change. The results of this research demonstrate the existence of meaningful relations among all variables. It is suggested to providers use the results of this work to analyze customer behavior and set their marketing plans accordingly. The results may be used in other services industries. Manuscript profile -
Open Access Article
51 - Consumer Involvement and Purchase Decision (Cell Phone as a Case Sstudy)
O. Mahdieh N. ChubtarashPurpose: To investigate the relationship between consumer involvement and purchase decision. Methodology: The present study has an applied aim and follows a descriptive (survey-correlation) method. The population was the students of Azad University of Sanandaj bra MorePurpose: To investigate the relationship between consumer involvement and purchase decision. Methodology: The present study has an applied aim and follows a descriptive (survey-correlation) method. The population was the students of Azad University of Sanandaj branch and the sampling method is stratified random. 372 people were chosen as a sample and questionnaire was used to collect data. Finding: Results of data analysis have shown confirmation of all hypotheses. In other word, there is significant relationship between dimensions of consumer involvement: Interest, Hedonic value, Sign value, Risk importance and Risk probability with purchase decision. Research Limitations: Since the target populations of the study were university students, the results of the study cannot be applied to other cell phone purchasers, Moreover, because cell phone was selected as the product, hence, application of the results of the study to other levels of the product is not possible. Managerial Implications: involvement is not an incontrollable variable for the company; managers and marketers can increase it by adding or emphasizing certain features of their offer and thus have an impact on consumers' decisions. Originality/value: Consumer involvement is a very important concept in marketing and consumer behavior but unfortunately there is little research about it. In this article this concept based on Kapferer and Laurant was surveyed and localized questionnaire was developed. Manuscript profile -
Open Access Article
52 - A Critique and Analysis of the Arguments of Believers in Hurmat and Permissibility of News from the Celestial Rulings
Mohammad Danesh Nahad (Corresponding author) Mohammad Hassan VakiliOne of the important topics in Islamic jurisprudence is identifying the obligation of Tanjim (belief in the effect of the state of the constellations and the movement of stars in human life and terrestrial events). Most jurists have considered Tanjim as haram, but MoreOne of the important topics in Islamic jurisprudence is identifying the obligation of Tanjim (belief in the effect of the state of the constellations and the movement of stars in human life and terrestrial events). Most jurists have considered Tanjim as haram, but such a ruling has fundamental problems and it is not the absolute argument for its hurmat (being haram). Not having a correct view of Tanjim leads to the issuance of an incorrect religious ruling. Accordingly, some have considered news of celestial rulings as haram (forbidden) and some as permissible. Those who consider Tanjim as haram, whose main reason is disbelief, have not paid attention to independent and non-independent causes, and this has caused their rulings regarding Tanjim to be insufficiently thorough. This study, with the library method, information analysis and comparison of opinions, looks for the problems in the absolute hurmat of Tanjim and to prove Tanjim as not being haram considering independent and non-independent causes. Because the non-independent reference of events to the heavens does not require any polytheism. the effects of these matters in the ruling of Tanjim has not been considered by researchers. Therefore, first the concept of tanjim is explained and after that, the ruling of news about celestial conditions rulings is examined to finally be able to examine the arguments for its hurmat and permissibility of the news of the celestial rulings in detail, or to reach the correct viewpoint. The findings include these items 1. Definite news of celestial rulings or belief in the influence of the stars is permissible, and this can not lead to disbelief and polytheism. 2. What causes the hurmat of Tanjim is the reference to an independent relation to the heavens, but non-independent reference does not have any corrupt consequences. 3. The arguments of the jurists on the hurmat of Tanjim is not absolutely complete. Manuscript profile -
Open Access Article
53 - A Jurisprudential and Legal Analysis of the Component of Permission to Limit Obligations
Hamid Khanmohammadi Abbas Karimi(corresponding author) Alireza Mazloom Rahni Mohammad BahmaniIn general, permission has a logical and conceptual appearance and can be appeared and shown in different ways. The basis of scholars has always been that if a person gives permission in a matter, he also authorizes the person in the tools and functions of that permissi MoreIn general, permission has a logical and conceptual appearance and can be appeared and shown in different ways. The basis of scholars has always been that if a person gives permission in a matter, he also authorizes the person in the tools and functions of that permission, and these tools of permission are not specified between the permission and the permitted person, but based on reason, this perception is created for the permitted person. There are factors in obligations that explicitly and implicitly limit it. Therefore, the purpose of this study is that permission and its functions can limit the obligation as a component, and this question is also raised as to how and to what extent the limitation is. Via examining a the descriptive-analytical method in jurisprudential and legal texts, permission is used as a component in obligations, and its tools and functions implicitly change the limits of the obligation and cause the increase, decrease, or cancellation of the obligation. Considering the past and present, no significant definition of permission has been seen in jurisprudence and law, and its legal nature has been a point of dispute and has been divided in different ways. In addition to the fact that permission has an explicit effect on the limits of the obligations, it is also implicitly effective and changes the limits of the permitted person’s obligations, and in some cases, in addition to the illegal possession, it will also have the effect of removing the guarantee. Therefore, the functions of permission are not merely limited to permission or permission in a legal event, but also in legal actions, and based on that, the limits of the obligation can be specified and determined, and the effect of possession can be considered useful. However, regarding the negation of the guarantee resulting from it, there are differences in different branches of Islamic jurisprudence (Fiqh) and law. Manuscript profile -
Open Access Article
54 - Nature and Effects of Revocation in Shaafeide Jurisprudents and Maalikee
Mohsen Ahmadi Adel ZiyaeiIqaalla-h is an agreement between two parties to revoke voluntarilya revocable contract. The legitimacy of revocation (iqaala-h) can bejustified based on Koranic verses and with the assistance of reason ,as well .Jurisprudents , however, consider traditions from the hol MoreIqaalla-h is an agreement between two parties to revoke voluntarilya revocable contract. The legitimacy of revocation (iqaala-h) can bejustified based on Koranic verses and with the assistance of reason ,as well .Jurisprudents , however, consider traditions from the holyprophet of Islam(p.b.u.h) sufficient in this regard, among whichthere is the tradition”.Anyone who accords with the other party’s willingness to revokean agreement , God will accept your(the prophet’s) intervention, onthe Doomsday, for that person’s sins to be forgive”. Thejurisprudents of two Islamic Sunni branches,Maalikee and Hanafee,regarded revocation (iqaalla-h) as a religiously recommendableaction (mosta-hab) which accords with pthe prophet’s traditions.Jurisprudents of the two Islamic branches, Maalikee and Hanafee ,all consent to revocation (iqaala-h) referring to the traditions of theholy prophet (p.b.u.h) and have stated its authenticity .However,there is disaccord among them concerning the definitions,conditions, nature and effects of revocation (iqaala-h). Manuscript profile -
Open Access Article
55 - Effect of Different Somatic Cell Levels on Nitrogen Components of Yoghurt Milk and Probiotic Set Yoghurt During Storage Life
A. Bavaria H. Ezzatpanah M. Aminafshar M. A. Mohammadifar -
Open Access Article
56 - Synthesis of activated carbon cellulose lignin residue in order to reduce nitrate from aqueous solutions, case study of drinking water in Mlard city
Maryam Khandani Lobat Taghavi Fariba Zamani HargalaniNitrate pollution is a pervasive and international challenge worldwide and trigger various environmental issues and negative effects on the earth. Therefore, studies and researches in the field of nitrate reduction from drinking water are crucial. The present study synt MoreNitrate pollution is a pervasive and international challenge worldwide and trigger various environmental issues and negative effects on the earth. Therefore, studies and researches in the field of nitrate reduction from drinking water are crucial. The present study synthesized activated carbon from plum kernel and then the effect of activated carbon produced in reducing the concentration of nitrate in the water of wells supplying drinking water in Mallard region. In this study, a sample of activated carbon adsorbent was synthesized by pyrolysis furnace method. The structure of synthesized activated carbon was confirmed using XRD, FTIR and BET analyzes. The results showed that at 25 °C, 120 min, pH=5 and with the activated carbon 80 mg L-1, nitrate concentration can be reduced 45%. Studies in Friendlich and Langmuir adsorption isotherm models also showed that the nitrate adsorption process completely followed the Langmuir adsorption equation and the value of R2 was 85 percent. The findings of the present study showed that activated carbon synthesized from plum kernel lingocellulosic residue is an acceptable option for reducing nitrate from aqueous solutions. Manuscript profile -
Open Access Article
57 - Effect of different levels of dietary probiotic bactocell on growth performance,survival and body composition in juveniles carp (Ctenopharyngodon idella)
Seyed Mehdi Hoseyni fard Shayan Ghobadi Mohadeseh GrailiIn this survey, effect of Probiotic Bactocell (Consist of Pediococcus acidilactici MA 18/5M) was examined on feeding, growth performance and survival rate of grass carp (Ctenopharyngodon idella) fry. 300 fish were prepared and fed by special diet made accordin MoreIn this survey, effect of Probiotic Bactocell (Consist of Pediococcus acidilactici MA 18/5M) was examined on feeding, growth performance and survival rate of grass carp (Ctenopharyngodon idella) fry. 300 fish were prepared and fed by special diet made according to American Soybean Association International Marketing (ASA-IM) principle. Four different treatments (control group with no probiotic, treatments 1, 2 and 3 each containing 0.1, 0.2 and 0.3 g probiotic Kg-1 of basal diet, respectively) were designed in triplicates. Results showed that Bactocell has no significant effect on feeding and growth parameters, but treatments 1 and 3 had the best performance. Although there weren’t any significant differences between fishes treated by 0.1 and 0.2 g Kg-1 Bactocell, most of the growth factors including body weight increase, percentage of body weight increase, specific growth rate and protein efficiency rate were better in fishes fed by the diet supplemented with 0.1g Kg-1 Bactocell. Manuscript profile -
Open Access Article
58 - Effect of dietary zinc oxide nanoparticle on leukocyte properties of rainbow trout (Oncorhynchum mykiss)
Houman Rajabi IslamiThe effect of zinc oxide nanoparticle as a mineral supplement in the diet on the white blood cells of rainbow trout was investigated in this research. Eight hundred specimens of rainbow trout fry (17.22±5.41 g) were randomly distributed in 18 experimental tank (s MoreThe effect of zinc oxide nanoparticle as a mineral supplement in the diet on the white blood cells of rainbow trout was investigated in this research. Eight hundred specimens of rainbow trout fry (17.22±5.41 g) were randomly distributed in 18 experimental tank (six treatments each with three replications). The basal diet was prepared without zinc supplementation and used for the negative control treatment. Other experimental diets were prepared by adding 10, 30, 50 and 70 mg/kg of zinc nanoparticles and 70 mg of zinc sulfate (positive control) to each kg of the basic diet. Blood samples were taken from the fish at the end of the experiment to check the number of white blood cells and their differential count. After two weeks of adaptation, the fish were fed for 8 weeks with the diets corresponding to each experimental treatment. Blood samples were taken from the fish at the end of the experiment to check the number of white blood cells and their differential count. The results showed that nano zinc oxide has a significant effect on the leukocyte count with the highest number of 178,000±22,000 No. mm-3 in fish fed diet supplemented with 50 mg kg-1 Nano ZnO, which was significantly more than their number in fish fed with basic diet (p<0.05). Furthermore, fish fed diet supplemented with 50 mg kg-1 Nano ZnO diet had the highest lymphocytes percentage of 72.21±0.13%, while the lowest percentage of neutrophils was also found in fish fed diet supplemented with 50 mg kg-1 Nano ZnO. However, the actual number of neutrophils in the blood of fish in this treatment was 4.5 folds more than those in the negative control treatment. Findings of the present study showed that zinc oxide nanoparticles have a significant effect on the leukocyte properties of rainbow trout. Manuscript profile -
Open Access Article
59 - Investigation on the physical and morphological properties of the biocomposite manufactured by mixing treated OCC pulp fibers and polypropylene with various molecular weights
Mohammadreza Amiri margavi Mohammad Talaeipour AmirHooman Hemmasi Hemmasi Behzad Bazyar Ismaeil GhasemiIn this study, the effect of the chemical treatment of OCC pulp and polypropylene molecular weight on the physical and morphological properties of cellulosic biocomposite was studied. For this purpose, OCC fibers were treated with acetic anhydride and then mixed with po MoreIn this study, the effect of the chemical treatment of OCC pulp and polypropylene molecular weight on the physical and morphological properties of cellulosic biocomposite was studied. For this purpose, OCC fibers were treated with acetic anhydride and then mixed with polypropylene and the compatibilizing agent (0 and 3%). The ratio of fibers and polymer materials was considered 30 to 70, which was manufactured by the hot-pressing method at 180 °C. The ratio of fibers and polymer materials was considered 30 to 70, which was manufactured by the hot-pressing method at 180 °C. The water absorption, volumetric swelling, and contact angle were measured on each sample according to the ASTM standards. Fourier transform spectroscopy (FTIR) and scanning electron microscopy (SEM) were used to investigate the chemical modification of fibers and the morphology of biocomposites, respectively. The results of the measurements showed that the effect of chemical treatment and polypropylene on contact angle and water absorption was significant and chemical modification of the fibers reduced the water absorption and volumetric swelling. Finally, FTIR analysis showed that hydroxyl groups were decreased and the SEM images indicated the bond between fibers and polypropylene was improved through chemical modification of OCC fibers. Manuscript profile -
Open Access Article
60 - Investigation of Silicon Nanowires Roles in Solar Cells
Ali Mahmoudloo Seyyed Sadegh Gholami -
Open Access Article
61 - Platinum Nanoparticles Deposited on Oxygen-Containing Functional Groups at Carbon Vulcane XC-72 as a Cathode Catalyst for Direct Methanol Fuel Cell
Sajjad Sedaghat Sharehjini Mohammad Yari Omid Moradi -
Open Access Article
62 - Design and Evaluation of a Mercury (II) Optode Based on Immobilization of 5, 6 Di methyl -1- (4 methyl benzyl) -2- para tolyl-1H-benzimidazole (DMBPTBI) on a Triacetylcellulose Membrane and Determination in Various Samples
A. Mosadeghei Fard G. H. Vatankhah -
Open Access Article
63 - Determining Areas Prone to Slope Movements
منیزه GahroodiInvestigating slope instability and determining areas prone to slope movements bymeans of GIS has been considered by researchers in the past recent years; however,sufficient attention has not been given to the methods employed in GIS.The present article uses a cell anal MoreInvestigating slope instability and determining areas prone to slope movements bymeans of GIS has been considered by researchers in the past recent years; however,sufficient attention has not been given to the methods employed in GIS.The present article uses a cell analysis method in a slope instability studyconducted at Sanandaj Country, and has obtained an appropriate model fordetermining prone areas. While testing the model, the cell analysis method has beencapable of assessing the factors influencing slope instability and creating modificationchanges in weights and coefficients Manuscript profile -
Open Access Article
64 - Determining Areas Prone to Slope Movements
علیرضا Shahabfar کوروش Ehteramian محمد MotamediInvestigating slope instability and determining areas prone to slope movements bymeans of GIS has been considered by researchers in the past recent years; however,sufficient attention has not been given to the methods employed in GIS.The present article uses a cell anal MoreInvestigating slope instability and determining areas prone to slope movements bymeans of GIS has been considered by researchers in the past recent years; however,sufficient attention has not been given to the methods employed in GIS.The present article uses a cell analysis method in a slope instability studyconducted at Sanandaj Country, and has obtained an appropriate model fordetermining prone areas. While testing the model, the cell analysis method has beencapable of assessing the factors influencing slope instability and creating modificationchanges in weights and coefficients. Manuscript profile -
Open Access Article
65 - Application of Era-Based Cellular Planning for Crisis Management of Earthquake in Tehran with Emphasis on Scenario Planning
mohadeseh Azimi A. A. Pourezzat آرین Gholipour A. A. SaadabadiTehran including earthquake-prone cities in the world those Seismic scientists have repeatedly warned about the earthquake in it. Recently, scientists have considered scenario planning and comprehensive programs for disaster. Therefore, era-based cellular planning (ECP) MoreTehran including earthquake-prone cities in the world those Seismic scientists have repeatedly warned about the earthquake in it. Recently, scientists have considered scenario planning and comprehensive programs for disaster. Therefore, era-based cellular planning (ECP) which has many scenarios to confront with probability future is suggested. For investigating the possibility of using this planning was interviewed with ten experts at universities and related organizations and used thematic technique for analysis data. 6 themes- how to scenario planning, relations between scenarios, step by step scenario planning and the most important scenarios for each phase - has finally been found. Paying attention to knowledge of scenario planning based on ECP's characteristics such as dividing scenarios to sub-scenarios, creating synergetic relations between sub-scenarios and consideration to era of each scenario is the innovation of research which shows that scenario planning is possible and it is necessary for studying in infrastructures to create better crisis management. Manuscript profile -
Open Access Article
66 - The experimental study of bio-engineered free-cell ostrich cornea as xenograft
M. Fatourehchi, H.R. Fattahian, A.M. Kajbafzadeh,Healthy cornea is a major element in optical pathway. Corneal blindness can occur due tovarious causes and different severities, and almost the best effective treatment is cornealallotransplantation. The limitation of allograft propounds the usage of other alternatives MoreHealthy cornea is a major element in optical pathway. Corneal blindness can occur due tovarious causes and different severities, and almost the best effective treatment is cornealallotransplantation. The limitation of allograft propounds the usage of other alternatives such asxenograft besides synthetic biomaterials and keratoprostheses. The aim of the study is toproduce Extra Cellular Matrix (ECM) with decellularization method in ostrichs cornea. TheOstrichs heads were obtained from a local slaughter house. All corneas were excised. ThenECM was prepared by the combination of chemomechanical and ionic detergent methods.Cellular components elimination and stromal structure were assessed by three types ofhistological staining and ultra-structural studies. Corneal transparency and thickness evaluatedin macroscopic observation.Histological staining of the decellularized cornea confirmed the complete removal of cornealcells as well as preserving the integrity of basement membrane. The ultra-structural studiesrevealed that decellularization process preserved the native structure of the stromal corneaalthough the collagen bundle space increased slightly. However, after immersing the acellularcornea in 100% glycerol, their optical properties regained to those native corneas.The authors believe that tissue processing method of ostrich cornea which applied in presentstudy can be used as an alternative tissue after completing other examinations such as cellculture, immunological and biomechanical properties. Manuscript profile -
Open Access Article
67 - Plaque formation by Newcastle virus strain V4 on cell culture and characterization with RT-PCR
Sobhani, S., Mehrabanpour, M.J. .. Cloned vaccines are used in many countries nowadays. One of the ways for cloning a virus is propagation of the virus on cell culture to obtain discrete different plaques in order to study their morphology and genetics. In this study monolayer Madin-Darby Canine Kidne More. Cloned vaccines are used in many countries nowadays. One of the ways for cloning a virus is propagation of the virus on cell culture to obtain discrete different plaques in order to study their morphology and genetics. In this study monolayer Madin-Darby Canine Kidney (MDCK) cell cultures were prepared by standard method. Various dilutions of the viruses were inoculated into monolayer MDCK cell cultures that were supplemented with magnesium sulfate and trypsin, and over laid with agar medium. The viruses could reproduce on these cells and caused cytopathic effect and plaques. At 10-6 virus dilution, 6 various shape and size discrete plaques were obtained and inoculated into allantoic fluid 9-11 days embryonated eggs. After 48 hrs, the allantoic fluids contain plaques were harvested and their RNA extracted. Cleavage site of fusion protein, with RT-PCR test was performed and the PCR products were purified and sequenced. The sequences of nucleotides and amino acids for each plaque were compared with those of the registered strain at gene bank as well as with each other. Molecular studies showed that all plaques are lentogenic strain of Newcastle disease virus and has about 97% to 99% homology with the strain V4 in the gene bank. The aim of this study is produce clear plaque by V4 strain of NDV on MDCK cell line and studies the molecular variations among them. Manuscript profile -
Open Access Article
68 - Study of rosemary extract on BCL2 and BAX gene expression in canine mammary gland carcinoma cell line (CF41.Mg)
Shabani, S., Mortazavi, P. .Apoptosis is named genetically programmed cell death and have special role in physiological and pathological conditions. BAX protein as a key protein in the apoptosis induced by various factors in the apoptosis pathway acts and BCL-2 have anti-apoptotic effect in respon MoreApoptosis is named genetically programmed cell death and have special role in physiological and pathological conditions. BAX protein as a key protein in the apoptosis induced by various factors in the apoptosis pathway acts and BCL-2 have anti-apoptotic effect in response to various stimuli of the mitochondrial apoptosis by preventing the release of cytochrome C applies. In this study, the effect of rosemary extracts on the expression of BCL-2 and BAX genes on breast cancer cells dogs (CF41.Mg). in in vitro examined and the control group (which cell line CF41.Mg without drugs) were compared Cells at doses of 5,10,25,50 and 100 micromole rosemary extract for 24,48 and 72 hours were exposed then by using MTT, the effect of drug on cell survival were analyzed. The tests in which different levels of rosemary extract was added to the cell culture, it was determined that rosemary extract induced cell death after 48 hours’ maximum amount to be allocated. The result suggests that the antitumor activity of the extract after 48 hours at a dose 25 mg/ml is more effective. The results of this study confirm the inhibitory effect of rosemary extract on canine mammary tumor cells (CF41.Mg). Manuscript profile -
Open Access Article
69 - Effects of different levels of salinity on number and size of chloride cells in gill of Benny fingerling (Barbussharpeyi)
Koohkan, O. .This study was accomplished to evaluate osmotic regulation ability of Benny fish by mitochondria-rich cells and study of the effect of salinity in different levels on their gill. For this purpose, 120 fish transferred into four aquariums containing 4, 8, 10 and 12 g/l s MoreThis study was accomplished to evaluate osmotic regulation ability of Benny fish by mitochondria-rich cells and study of the effect of salinity in different levels on their gill. For this purpose, 120 fish transferred into four aquariums containing 4, 8, 10 and 12 g/l salinity, after a week adaptation. Sampling was carried out after 96hrs and tissues prepared and fixed in 10% formalin for 48hrs. After tissue processing, 5µm sections were prepared and stained with haematoxylin and eosin and studied by light microscope. The observations showed most presence of chloride cells in basement of filament and lower in lamellae of Barbussharpeyi. Chloride cells and mucosal cells increased in size and number with salt concentrations increasing and showed significant different in some treatments (P<0.05). Mucosal cell number in12 g/l concentration showed significant increasing compared to both control group and 4 g/l concentration, but no significant difference with other treatments. In chloride cells, only 12 g/l treatment showed a significant difference (p<0/05) compared to control group in number and size. Manuscript profile -
Open Access Article
70 - Study on effects of selenium on histopathology and histometrical parameters in testis of normal and experimental varicocele rats
Taghizadeh, L., Eidi, A., Mortazavi, P., Haeri Rohani, A. .Negative effects of oxidative stress on serum, semen and testicular tissue have shown in patients with varicocele or in animal models. This study investigated the effects of sodium selenite on histological and histometrical parameters in testis of normal and varicocele- MoreNegative effects of oxidative stress on serum, semen and testicular tissue have shown in patients with varicocele or in animal models. This study investigated the effects of sodium selenite on histological and histometrical parameters in testis of normal and varicocele-induced male Wistar rats. Forty-four rats were divided randomly in 11 groups: control group (1 ml/kg of saline intraperitoneally), sham-operated control group (only surgery without varicocele, 1 ml/kg of saline intraperitoneally, experimental varicocele groups (sodium selenite at doses 0.05, 0.1, 0.2, and 0.4 mg/kg, intraperitoneally) and normal experimental groups (sodium selenite at doses 0.05, 0.1, 0.2, and 0.4 mg/kg, intraperitoneally). Two months after surgery using Turner method, varicocele was induced in rats. Then, sodium selenite was administered continuously for 60 days. Testis tissue samples were collected for histological and histometrical studies. Sodium selenite caused a significant increase in thickness of epithelium of seminiferous tubules compared to varicocele control group (P<0.01). Tubular differentiation index (TDI) and spermiogenesis index (SI) of seminiferous tubules showed an increase in sodium selenite groups compared to normal control group. TDI and SI of seminiferous tubules showed a significant decrease in varicocele control group compared to normal control group (P<0.05). Sodium selenite caused a significant increase in number of leydig cells in varicocelized rats, compared to varicocele control group (P<0.01). Taken together, the results of this study suggest that selenium treatment may have beneficial effect on the testis tissue of varicocelized rats. Manuscript profile -
Open Access Article
71 - Effects of human chorionic gonadotropin on spermatogonial stem cell colony formation and differentiation after in vitro Coculture with Sertoli cells
Narenji Sani, R., Tajik, P., Damghanaian, N., Javdani, G. .Spermatogenesis is a complex developmental process that originates from spermatogonia stem cell. This process consists of sequential, highly organized steps of cell proliferation and differentiation resulting in the generation of functional spermatozoa. Therefore, the a MoreSpermatogenesis is a complex developmental process that originates from spermatogonia stem cell. This process consists of sequential, highly organized steps of cell proliferation and differentiation resulting in the generation of functional spermatozoa. Therefore, the aim of the present study was to determine the effects of human chorionic gonadotropin (hCG) on spermatogonial stem cell colony formation and differentiation after in vitro Coculture with Sertoli cells. In this experimental study, Sertoli and spermatogonial cells were isolated from 3- to 5-month-old calves. Co-cultured Sertoli and spermatogonial cells were treated with hCG in treatment groups before colony assay with 2, 5 and 10 IU/ml culture medium. Vimentin and oct-4 immunohistochemical staining were used for Sertoli and spermatogonial stem cell colony detection, respectively. The present study showed that hCG increase both colony diameter and colony number. hCG can induce both proliferative pathway and differentiation process in SSCs Coculture with Sertoli cells. Manuscript profile -
Open Access Article
72 - Evaluation of the effects of celecoxib on mouse lymphoma cells (EL4)
Leyla Emami Sh Safi Farhad ZakerLymphoma is one of the most common tumors in most species of the mouse. On the other hand, biologic, histopathologic and epidemiological characteristics of mouse lymphoma are similar to lymphoma in humans. Hence, tumor lymphoma in mice can be a suitable model for the bi MoreLymphoma is one of the most common tumors in most species of the mouse. On the other hand, biologic, histopathologic and epidemiological characteristics of mouse lymphoma are similar to lymphoma in humans. Hence, tumor lymphoma in mice can be a suitable model for the biological study of human cancers. The objective of the present study was to evaluate the apoptotic and cytotoxic effects of celecoxib on mouse lymphoma tumor cells (EL4) using Annexin/PI and MTT assays. The results of MTT showed a dose and time-dependent inhibition of EL4 cells by celecoxib and 50% inhibition of cell survival at 20 μm of celecoxib. In addition, the percentage of cells with apoptosis increased after 48 hours exposure to IC50 concentration (50% survival of the exposed cells) of celecoxib. Based on the obtained results, it seems that celecoxib can be used as an adjunct therapy along with other compounds used to treat lymphoma in mice and probably in human medicine. Manuscript profile -
Open Access Article
73 - Evaluation of the effect of Melittin on liver and renal biochemical markers and KI67 expression in mice with experimentally-induced breast cancer
F. Dabbagh Moghaddam, , S. Hamedi , P Mortazavi , M. Nabiuni N. Hayati Roodbari,Despite extensive progress in the production of anti-cancer drugs, attention to some natural products, such as Melittin from honey bee venom, is growing. Some studies have shown that this product has anti-cancer properties. To evaluate the effects of Melittin on functio MoreDespite extensive progress in the production of anti-cancer drugs, attention to some natural products, such as Melittin from honey bee venom, is growing. Some studies have shown that this product has anti-cancer properties. To evaluate the effects of Melittin on function breast cancer indicators in inbred Balb/c mice as well as its effects on liver and renal enzymes, 4T1 cell lines were purchased from Pasteur Institute and were cultured and the induction of breast cancer was performed in the breast area of mice. The 20-day treatment period was performed in 9 groups (including 6,3,1mg/kg body weight of Melittin, doxorubicin, cisplatin, PBS, DMSO, healthy control, negative control). At the end of the course, animal blood samples were taken then liver and renal biomarkers were measured after serum isolation. From the induced tumor tissue sample, after fixation in formalin, the immunohistochemical tissue slide was prepared and studied for KI67 expression. Results showed that renal (BUN) and liver biochemical markers (AST, ALT as well as ALP) had no significant changes in melittin treated group at the dose of 6 mg/kg compared to control group. The results of histopathology showed a decrease in tumor cell invasion in Melittin therapeutic groups, which was more evident at a dose of 6 mg/kg. In immunohistochemistry, KI67 expression did not show a significant change in all groups. The results of this study show the beneficial effect of melittin in preventing the growth of tumor cells without injuring the liver and kidneys compared to other common drugs. Manuscript profile -
Open Access Article
74 - Anticancer Effects of Glucan Polysaccharide of Fusarium spp and Its Chemical Analysis by FT-IR and HPLC
, B. Salehi , M. Bayat , M. Dezfulian , A Sabokbar , B. TabaraieCancer is the second factor of death in world on the basis of WHO reports on 2018. Application of fungal polysaccharides is one of the cheaper, less dangerous, less side effects, and newer in the treatment and prophylaxis of cancer. Object of this research is isolation MoreCancer is the second factor of death in world on the basis of WHO reports on 2018. Application of fungal polysaccharides is one of the cheaper, less dangerous, less side effects, and newer in the treatment and prophylaxis of cancer. Object of this research is isolation and identification of endemic fusarium fungus, its glucan extraction, determination of chemical characteristics by HPLCand FT-IR and anticancer effects on cell lines of LCL, Hela.In this study fusarium fungus was isolated from soil of karaj district and identified on the basis of microscopic and macroscopic and genetical characteristics as a fusarium genus .Then fungus was grown into selective broth medium for obtaining of the most biomass for extraction of glucan .Glucan of fungus was extracted by boiling water method.Different amounts of extracted glucan were treated to the cell cultures of lcl and Hela and its cytotoxicity effects were surveyed.Results showed that glucan polysaccharide had anticancer effects against cell lines of LCL and no anticancer effects against Hela cell lines. Cytotoxicity effects of glucan showed by colorimetry MTT method. Manuscript profile -
Open Access Article
75 - Study of kidney anatomy and microscopic of renal proximal and distal tubules of middle and posterior part of kidney tissue in Oncorhynchus mykiss and Astronotus ocellatus
. S Mohammadalipour Iraj pousty , S HesarakiThe present study was conducted to compare the histology of renal proximal tubules (I) and (II) in two species (Rainbow trout and Oscar). Rainbow trout, known as Oncorhynchus mykiss scientific name from the Salmonidae family which is cultivated and freshwater. Oscar fis MoreThe present study was conducted to compare the histology of renal proximal tubules (I) and (II) in two species (Rainbow trout and Oscar). Rainbow trout, known as Oncorhynchus mykiss scientific name from the Salmonidae family which is cultivated and freshwater. Oscar fish, the scientific name is Astronotus Ocellatus, which is one of the most well-known ornamental fish of the Chichlidae family. Five piece of the two fish species were selected randomly and their macroscopic specification and morphometric measurements were recorded. Samples were fixed in %10 formalin buffer and the cuts were prepared with a thickness of five micron and then they were stained by Hematoxylin and eosin and Periodic acid–Schiff method and studied by light microscopy. The data were analyzed with SPSS software and T-Test statistical test (P <0.05). Proximal and distal tubes were detected and the variables were measured. The size of the cell nucleus and the outer diameter of the proximal (I) had a significant difference (P<0.01). There has been significant difference in the number and the size of cell and its nucleus, the inner and outer diameter of the proximal II between two species (P<0.001). The number, cell size of the distal tubules has been significant difference between two species (P<0.01). The size of the cell nucleus, the inner and outer diameter of the distal tubules have been significant difference between two species (P<0.001). According to the results, the anatomy and histology of kidney tissue are different in the Rainbow trout and Oscar fish. Manuscript profile -
Open Access Article
76 - Microfluidics and improving the cell culture channel: evaluation of spermatogonial stem cells using microfluidic chips
S. Naeemi A.M. Kajbafzadeh, A. Eidi, R. Khanbabaee, H. Sadri-ArdekaniThe main purpose of the present study was to investigate the treatment of male infertility, because infertility treatment is important in the group of cancer patients treated with gonadotoxic drugs. The main approach of the mentioned study is to compare two different gr MoreThe main purpose of the present study was to investigate the treatment of male infertility, because infertility treatment is important in the group of cancer patients treated with gonadotoxic drugs. The main approach of the mentioned study is to compare two different groups of spermatogonia stem cell culture methods and to evaluate the efficiency of differentiation and proliferation of these group of cells. Successful transplantation of spermatogonia stem cells (SSCs) in laboratory studies requires a suitable microenvironment for proliferation and differentiation of these cells. The natural extracellular matrix provides a good environment for stem cell culture. In the present study, themain purpose was to evaluate the ability of spermatogonial stem cells proliferation and differentiationvia the utilizing the microfluidic device (ex vivo). On the other hand, in the present study, we compared the obtained resultswith culture conditions in conventional culture plates (in vitro) to compare the SSCs proliferation and differentiation ability. In in-vitro culture method first spermatogonia stem cells from neonatal mice were isolated, then the resulted cells were seeded in culture plates on a scaffold consisting of hyaluronic acid, chitosan and decellularized testicular tissue, furthermore, in ex-vivo study the extracted spermatogonial stem cells were cultured in the microfluidic system without a scaffold. In ex vivo study, spermatogonial stem cells were extracted from neonatal male NMRI mice. The extracted cells were transferred to a microfluidic chip that was designed without an external pump, thereafter, the culture process was evaluated by IHC evaluation after one-month culture. In examined samples, cell attachment to the seminiferous tubules, DAPI staining and immunohistochemistry were evaluated. The results of immunohistochemical studies showed a significant increase in the expression of PLZF and TEKT1 markers in ex-vivo models. Finally, the results revealed that the ability of spermatogonia stem cells to induce spermatogenesis and production of haploid cells under testicular tissue culture in the microfluidic system is much more significant than conventional culture conditions in laboratory plates for these cells. Manuscript profile -
Open Access Article
77 - Diagnostic Value of Milk Enzymatic Markers Lactate Dehydrogenase and Alkaline Phosphatase for Subclinical Mastitis in Dairy Cattle
سعید Akbari Aliabad S. O. Ghasemian S. Z. PeighambarzadehMastitis could be diagnosed by diverse methods, including physical, clinical, and laboratory tests. The present study aimed to evaluate the accuracy of subclinical mastitis diagnosis using enzymatic diagnostic tests for milk lactate dehydrogenase (LDH) and alkaline phos MoreMastitis could be diagnosed by diverse methods, including physical, clinical, and laboratory tests. The present study aimed to evaluate the accuracy of subclinical mastitis diagnosis using enzymatic diagnostic tests for milk lactate dehydrogenase (LDH) and alkaline phosphatase (ALP). This study was performed on 90 Holstein cows selected randomly out of high- and low-yielding dairy cattle. According to the result of the California Mastitis Test, two milk samples were obtained from the intended udder quarters based on the principles of the National Mastitis Council. One specimen was used for microbial culture and the other one was utilized for somatic cell count (SCC), as well as milk LDH and ALP tests by diagnostic kits. Considering microbial culture as the gold standard for subclinical mastitis diagnosis, the sensitivity of SCC, ALP, and LDH tests was 87%, 59.3%, and 70.4%, respectively. Moreover, the specificity of these tests was 77.8%, 80.6%, and 77.8%, respectively. Our findings revealed a strong correlation between SCC, LDH, and ALP. It was observed that an increase in SCC was accompanied by augmented LDH response. According to the results of the present study, SCC was the most efficient test for diagnosing subclinical mastitis in dairy cows, followed by LDH and ALP. Manuscript profile -
Open Access Article
78 - Decellularization of ostrich plantar ligament
روزبه Moridpour حمیدرضا Fattahian پژمان MortazaviThe use of tissue is very common to return organ function nowadays. Tissue engineering and novel preparation techniques in therapy are a main role. In present research use of chemical and physical methods was tried to prepare tissue from connective tissue of plantar str MoreThe use of tissue is very common to return organ function nowadays. Tissue engineering and novel preparation techniques in therapy are a main role. In present research use of chemical and physical methods was tried to prepare tissue from connective tissue of plantar structure of ostrich. Five pair of ostrich is feet separated of tarsometatarsal joint were sent to laboratory. Microscopic study and biomechanical evaluation were performed. De-celluraization of the tissue was done with sodium dodecyl sulfate and vacuum. Finally, light and electron microscope studies were carried out. Biomechanical evaluation was done as well. Ligamentum plantar composed of fibrocartilage tissue that decellularization process last as percent of cells and their nucleus content. There was not significant difference between prepared tissue and original tissue in tension and compression parameters. SDS with vacuum decellularized till as percent with connective tissue unchanged with minimal antigenicity feature as xenograft. The tissue could be used after sterilization in patient in future. Manuscript profile -
Open Access Article
79 - Identification of a new strain of the respiratory virus in the green iguana (Iguana iguana)
پیمان Mohammadzadeh سجاد MohammadiRecently, nidoviruses have been described as a possible cause of severe respiratory diseases in reptiles and especially pythons from different parts of the world. The aim of this study is to isolate the pathogenic agent along with the precise determination of its charac MoreRecently, nidoviruses have been described as a possible cause of severe respiratory diseases in reptiles and especially pythons from different parts of the world. The aim of this study is to isolate the pathogenic agent along with the precise determination of its characteristics and to examine the histopathological findings in a female iguana. During the iguana post-mortem examination, pyogranulomatous and fibronecrotic lesions were observed in various organs other than the respiratory system, and the results of the reverse transcription polymerase chain reaction were also positive. Therefore, the relationship between the observation of these extensive lesions and the Necropsy findings obtained from Previous cases of serpanovirus infection and the amount and type of changes in the genome of the serpentovirus identified with the previous serpentovirus were investigated. Cell culture inoculation and then RT-PCR was used to collect and obtain the virus isolate. Next, immunohistochemistry was performed. Staining for the nucleoprotein of the serpentine virus showed that this virus infects not only a wide range of epithelia (respiratory and gastrointestinal epithelium, hepatocytes, urinary tubules, pancreatic ducts, etc.), but also contaminates the intravascular monocytes, intralesional macrophages, and endothelial cells too. With next-generation sequencing, the complete genome for this new serpentine virus species was obtained.The analysis of the viral genome recovered from this respiratory and systemic disease associated with serpentine virus infection did not show a sequence correlation with the phenotype of other strains. The results showed that this serpentine virus has a wide cell and tissue tropism, and the course of infection by it can be different, and as a result of the systemic spread of the virus in the body, it causes lesions in a wide range of different body systems. Manuscript profile -
Open Access Article
80 - Studying the therapeutic effect of artemisinin along with endometrial stem cells containing TSP-1 gene on Alzheimer's disease in streptozotocin-induced Alzheimer's-diabetes model of rat
پروین Poorgholam پریچهره Yaghmaei مهدی Noureddini زهرا HajebrahimiAlzheimer's is the most common neurodegenerative disease of the elderly. Oxidative stress and inflammation play an important role in Alzheimer's disease. The risk of Alzheimer's disease is high in diabetic people, and insulin resistance occurs in the brain of Alzheimer' MoreAlzheimer's is the most common neurodegenerative disease of the elderly. Oxidative stress and inflammation play an important role in Alzheimer's disease. The risk of Alzheimer's disease is high in diabetic people, and insulin resistance occurs in the brain of Alzheimer's patients. Accumulation of amyloid plaques leads to angiogenesis and increased permeability of the vessels. Today, medicinal plants are receiving attention due to fewer side effects than chemical drugs. In the present study, the protective effect of Artemisia herbal product (artemisinin) along with endometrial stem cells containing the antiangiogenesis gene (thrombospondins-1 or TSP-1) was investigated in Alzheimer's disease induced by streptozotocin in a diabetic male rat laboratory model. 3 days after the induction of Alzheimer's and diabetes using streptozotocin, the animals received stem cells intranasally and then received artemisinin for one month (50 mg/kg). Initial and final weight, blood sugar, and interleukin-6 serum levels were measured, and brain amyloid plaques were examined by hematoxylin-eosin staining. The results showed that the induction of Alzheimer's and diabetes led to a significant decrease in body weight and an increase in blood sugar, interleukin-6, and brain amyloid plaques. Treatment with artemisinin and stem cells, separately and simultaneously, improved these parameters. The findings of this research showed that human endometrial stem cells that contain the TSP-1 gene can be used as a potential source of stem cells along with natural antioxidants artemisinin to reduce the symptoms of Alzheimer's disease. Manuscript profile -
Open Access Article
81 - Effect of Land Use Trends on the Amount of Agricultural Water Consumption in Urmia Lake Watershed in the Next 20 Years Using Markov Chain
Kiyoumars Roushangar Mohammad Taghi Aalami Hassan GolmohammadiBackground and Aim: Reducing the water level of Urmia Lake and its effects on the environment around the lake has been one of the important national and international issues and challenges in the last two decades. In accord with the studies, one of the critical factors MoreBackground and Aim: Reducing the water level of Urmia Lake and its effects on the environment around the lake has been one of the important national and international issues and challenges in the last two decades. In accord with the studies, one of the critical factors affecting this declining trend has been the rise in harvest, especially for agriculture. Accordingly, the purpose of this study is to simulate the future status of water resources in the Urmia Lake basin, influenced by the area of agricultural land uses.Method: For this purpose, Landsat satellite image data for the period 2000 to 2020 are firstly classified using the SVM algorithm in ENVI5.3 software and the classification accuracy is analyzed using the Kappa Coefficient algorithm.In the following, the statistics and information related to the change of cultivation pattern (from arable to garden) and water sources discharging Lake Urmia are calculated. In the next step, the simulation of land use changes for 2030 and 2040 is done using two LCM and CA-MARKOV methods. And finally, after determining the amount of changes in each land use, the amount of water required for agricultural affairs in the catchment is simulated using NETWAT model.Conclusion: The results show that the area of two uses, irrigated agriculture and garden will increase from 1450 and 395 square kilometers in 2000 to more than 3600 and 1650 square kilometers in 2040, respectively, This will increase the amount of water Needed or agriculture from 1,500 million cubic meters in 2000 to more than 4,100 million cubic meters in 2040.Results: From 2000 to 2020, water consumption in irrigated agriculture has increased by 1253.05 Km2; which according to Markov's prediction method, this amount will reach 2049.54 Km2 in 2040 that raises the amount of water consumption by 1 billion and 473 million cubic meters. The gardens land use has increased by 688.02 Km2 from 2000 to 2020, and according to Markov's prediction method, this amount will reach 1276.14 Km2 in 2040, which raises the amount of water consumption by 703 million cubic meters. From 2000 to 2020, 367.06 Km2 has been added to the drayland farming, which according to the prediction of Markov method, this amount will reach 531 Km2 in 2040, which soars the amount of water consumption by 253 MCM. Manuscript profile -
Open Access Article
82 - Millenarianism in Ancient Iranian Religions and Ikhwān al-Safā’s Theory of Prophetic Cycles: A Comparative Study
رضا فرحقیقی انشاءالله رحمتیZoroasterianisam, Zurvanism and Mithraism have been combined withastrological beliefs in such a way that it is nearly impossible to graspthese schools and religions without having knowledge aboutastrological beliefs. Ikhwān al-Safā, a mystical and esoteric associationin MoreZoroasterianisam, Zurvanism and Mithraism have been combined withastrological beliefs in such a way that it is nearly impossible to graspthese schools and religions without having knowledge aboutastrological beliefs. Ikhwān al-Safā, a mystical and esoteric associationin tenth century in Basra and Baghdad, wrote 52 epistles full of religioastrologicalbeliefs and thoughts. For example their theory of PropheticCycles was developed to explain the cosmic cycles and the sacredhistory. Observing similarities between ancient Iranian religions andIkhwān al-Safā and after surveying the religio-astrological elements ofIranian millenarianism (especially that of Zoroasterianism andZurvanism) and Ikhwān al-Safā’s Prophetic Cycles, we decieded tocompare these two religious traditions. In the present research, by usingscientific and historical references, we have tried to recognize andanalyze the common roots of these beliefs and thoughts in the bothtraditions. The most significant achievement of this research ispresenting a new method for comparison between the ancient Iranianconcept of ontological levels and Ikhwān al-Safā’s concept of celestialsouls. Moreover, by surveying the role of the archetypes of infiniteTime and eternal Place in the immaterial and material world, we couldmake a comparison between Yazatas and Ameshaspentas of ancientIranian religions and Ikhwān al-Safā’s consepts of Universal Reason,Universal Soul and Celestial Souls. Manuscript profile -
Open Access Article
83 - Optimization of gluten-free cookie formulation containing rice flour, brown rice germ, peanut and flaxseed
H. Asadolahnezhad Roodbaneh S. Jafarian L. Roozbeh Nasiraie M. Sharifi SoltaniIntroduction: Cookies are important sweets that are the most desirable products of the family of sweets for people of all ages due to their long shelf life and low production cost. Eliminating sugar, replacing unsaturated fats and producing a gluten-free product can hel MoreIntroduction: Cookies are important sweets that are the most desirable products of the family of sweets for people of all ages due to their long shelf life and low production cost. Eliminating sugar, replacing unsaturated fats and producing a gluten-free product can help improving the health level of society, and in this way, cookies can be used as a product to deliver essential nutrients to the body of people with celiac disease.Materials and Methods: In order to carry out this project, gluten-free cookie treatment was performed based on the cookie formulation and based on the highest response level. Independent variables included peanut flour (5 to 15%), rice flour (65 to 90%), brown rice sprout flour (5 to 15%) and flaxseed powder (0 to 3%) and response variables included; water activity, hardness, expanding ratio and overall acceptability were considered. The functional relationship between the parameters affecting the formulation of gluten-free cookies was determined using the experimental design of Box-Benken.Results: In this study, the aim of optimization is to achieve the highest percentage of expanding ratio, hardness and overall acceptability, as well as reducing the amount of water activity, which are important quality indicators of cookies. Based on the selected models, the optimal formulation selected by the software was introduced including 88.23% rice flour, 15% brown rice sprouts, 1.55% flaxseed and 11.45% peanuts. Based on the results, with the increase of all 4 independent factors, the amount of expandability, the amount of stiffness and overall acceptance increased and the amount of water activity decreased. In general, high quality cookies have good hardness, high expanding ratio, less irregular appearance, brown color, attractive appearance and pleasant flavor.Conclusion: The combined use of these compounds in appropriate concentrations can be used as a gluten-free product in addition to increasing the hardness and width ratio, without adversely affecting the sensory properties of the cookie, with beneficial nutritional and health properties, which can be significantly useful for the health of people with celiac disease. Manuscript profile -
Open Access Article
84 - Determination of Quality Indices as Criteria to Assess Traditional Taftoon Bread Quality
L. Kamali Rosta M. Seyedain Ardabili Gh. Asadi B. Ghiassi Tarzi R. AzizinejadIntroduction: In spite of the long production and consumption of traditional Taftoon bread, documented qualitative indices were not completely determined for this product. Providing such indices, defining them and preparing their quantitative scope for production of thi MoreIntroduction: In spite of the long production and consumption of traditional Taftoon bread, documented qualitative indices were not completely determined for this product. Providing such indices, defining them and preparing their quantitative scope for production of this bread is considered essential. Materials and Methods: To prepare three types of Taftoon bread, three flours with different quantities and qualitative characteristics and with appropriate extraction rate for the flour namely strong, medium and weak were made. Physical, chemical and rheological evaluations concerned with flour and dough types were determined. The physical and chemical properties of flour and dough were examined followed by the characterization factors namely texture, porosity, microstructure, staling process of the bread made from it both freshly and during storage by different methods. Results: The results of physical, chemical, instrumental and sensory tests significantly correlated with each other. Taftoon bread from medium flour as compared to other breads had more moisture retention, less texture firmness, slower starch retrogradation and lower staling process, more porosity, higher sensory scores and generally had better quality both freshly and during storage. This was due to the flour qualitative characteristics of this type of bread to obtain dough with appropriate elasticity and excellent sheeting capability. Conclusion: Qualitative indices of Taftoon bread types with different quality levels can be used in documentation system and will be effective to improve the quality of this product and reduce the waste. The results might also help to provide information concerned with the use of flour with desirable characteristics for the production of Taftoon bread with specific quality. Manuscript profile -
Open Access Article
85 - Characterization of Edible Film prepared with HPMC Containing Sage Essential Oil
Reza Ghadermazi Javad Keramat seyyed AmirHossein GoliIntroduction: In recent years, edible films and coatings have received much attention in food packaging. These packaging’s displays suitable film-formation properties such as their biodegradable and carrier of food additive such as antioxidant, antimicrobial, colo MoreIntroduction: In recent years, edible films and coatings have received much attention in food packaging. These packaging’s displays suitable film-formation properties such as their biodegradable and carrier of food additive such as antioxidant, antimicrobial, color and nutrients. Materials and Methods: The antioxidant activity (AA) of sage essential oil (EO) in various in vitro model systems was investigated. Physical and AA of Hydroxypropylmethylcellulose (HPMC) film with sage essential oil were also evaluated. Results: In order to determine the AA of sag essential oil with DPPH radical scavenging, β-carotene/linoleic acid bleaching and reducing power assays, IC50 values were 907.7, 454.2 and 1362.42 µg/ml respectively and sag essential oil showed lower AA as compared to BHT. Addition of essential oil to film led to 1.5 times decrease in water vapor (WVP) and 1.7 times decrease in oxygen permeability (OP). Films with essential oil have a lower transparency as compared to films without essential oil as lightness reduced from 95.47 to 90.3. The addition of essential oil resulted in a significantly decrease in tensile strength (3 times) and elastic modulus (2.1 times) but elongation percentage haven’t significant difference (P>0.05) with films without essential oil. Film with sage essential oil showed good protective effects against soyabean oil oxidation as peroxide value of the samples without HPMC film coating, packed by film and film with sag essential oil was 92.7, 85.9 and 66.3 meq O2/kg oil respectively. Conclusion: The WVP and OP of HPMC edible film were improved by the addition of sage essential oil. Also, combination of essential oils into HPMC film is a suitable method for reducing of lipid oxidation. Manuscript profile -
Open Access Article
86 - The Effect of the Cress Seed Gum and Pectin on the Qualitative and Organoleptic Characteristics of Gluten- Free Pasta
A. H. Sarraf M. Salehifar L. Shahsavani MojaradIntroduction: In gluten-free pasta there is a need to use materials that can partially simulateviscoelastic properties of gluten in the dough and have the ability to replace gluten. The aimof this study is to investigate the potential of replacing gluten in cassava star MoreIntroduction: In gluten-free pasta there is a need to use materials that can partially simulateviscoelastic properties of gluten in the dough and have the ability to replace gluten. The aimof this study is to investigate the potential of replacing gluten in cassava starch-based pastaformulation by using cress seed gum and pectin and evaluate the qualitative and organolepticproperties of gluten-free pasta and finally optimize pasta formulation.Materials and Methods: In this study, pectin at three concentrations of 1%, 2% and 3% andcress seed gum at concentrations of 0.5%, 1% and 1.5% were employed. Weight after cooking(baking numbers), the percentage of solids in the cooking water (glazing), adhesion, color,moisture and sensory evaluation were investigated. Statistical analysis of the result wascarried out by response surface method (RSM).Results: The results indicated that the addition of pectin and cress seed gums concerned withthe weight after cooking (cooking number), total soluble solid in cooking water (glazing),adhesion, color were significant at 0.05% level. The sensory evaluation based on hedonicmethod showed significant level at 0.05% level as concerned with taste, odour, texture andover all acceptability.Conclusion: It was concluded that the addition of pectin and cress seed gums causedincreases in moisture and cooking number. The results of glazing and adhesion indicated thatby increasing the concentration of pectin, glazing is decreased linearly and by increasing theconcentration of cress seed gum glazing is in increased linearly in the case of gluten freepasta. The application of Hunter lab regarding the evaluation of colour L * is decreased whilea * and b * is increased nonlinearly by the addition of both cress seed and pectin gums. Theresults concerned with the organoleptic test showed that both pectin and cress seed gumschanged the taste and odour. The assessors gave the highest score to the samples containing1% cress seed and 2% pectin gums concerned with colour, texture and overall acceptability. Manuscript profile -
Open Access Article
87 - Investigation of the Effect of Hemicellulase in Heat Reflux and Ultrasound Extraction Methods on Extraction Efficiency of Glycyrrhizic Acid of Licorice Root
E. Giahi J. Keramat M. JahadiIntroduction: Enzyme assisted extraction methods have been recently reported for the extraction of bioactive compounds. The aim of this research is to investigate the effect of hemicellulase enzyme on the extraction efficiency of the extract and the extraction of glycyr MoreIntroduction: Enzyme assisted extraction methods have been recently reported for the extraction of bioactive compounds. The aim of this research is to investigate the effect of hemicellulase enzyme on the extraction efficiency of the extract and the extraction of glycyrrhizic acid from licorice root through reflux and ultrasound extraction methods. Materials and Methods: After the preparation of licorice root, the enzymatic pretreatment was performed by hemicellulase enzyme at different concentrations (0.2, 1, 2, 3 %) for 1 hour in waterbath at 45°C. The extracts were obtained by both reflux and ultrasound methods (20 minutes at 35°C with 40 khz frequency), followed by centrifugation, concentration and drying in an oven. The extraction efficiency of the extract was calculated and the amount of glycyrrhizic acid was measured by HPLC method. Results: The extraction efficiency of the extract was increased significantly as the hemicellulase enzyme concentration was increased, therefore the extract from the enzymatically pretreated licorice root with hemicellulase enzyme in both extraction methods at the concentration of 3% led to the maximum extraction efficiency and there were significant differences between the control and the enzymatically pretreated samples (p<0.05). Conclusion: Enzymatic pretreatment of the licorice root with hemicellulase enzyme in both reflux and ultrasound extraction methods is an effective method to increase the extraction efficiency of glycyrrhizic acid from licorice root. The enzyme with the capability of cell wall breakage of plant tissue facilitates the release of the intracellular materials. Manuscript profile -
Open Access Article
88 - Optimisation of the Conditions for Using Protease and Hemicellulase in Wafer Formulation
Babak Ghiassi Tarzi Venushe Babaei Nami Parviz Shahbazikhah Haleh HadaeghIntroduction: Economic issues concerned with the demand for energy reduction and costs as well as improved quality of the final product in the bakery industry such as Wafer production is of great importance.Materials and Methods: In the present study the effects of appl MoreIntroduction: Economic issues concerned with the demand for energy reduction and costs as well as improved quality of the final product in the bakery industry such as Wafer production is of great importance.Materials and Methods: In the present study the effects of applying different amounts of Protease (0.005-0.05% of the weight of flour), Hemicellulase (0.005-0.05% of the weight of flour), water reduction (0-20%), dough resting time (0-30 min) and the baking time (90-150 sec) on decreasing the waferbatter viscosity and some quality factors of wafer sheet were investigated and compared with the control sample. The amounts of batter viscosity, moisture, crispness and colour of wafer sheet were considered in order to evaluate the effects of various levels of protease and hemicellulas enzymes on the mentioned parameters. Optimisation of the process condition was conducted to determine the optimum formulation for producingwafer sheet.Results: The results were analyzed by Response Surface Methodology (RSM) and showed that optimal level of Protease enzyme, Hemicellulase enzyme, water reduction of formulation, dough resting time and baking time were 0.05%, 0.05%, 9.58%, 30 min and 135.17 sec, respectively.Conclusion: Protease and hemicellulase enzymes might be used in wafer sheet formulation and these enzymes have positive effects on dough and some quality factors of the final product such as moisture and crispiness. According to the variation of the flour quality, the production of wafer will beless dependenton the flour quality. Manuscript profile -
Open Access Article
89 - The Antifungal Effects of Hydroalcoholic Extract of Thyme (Thymusvulgaris) and Carboxy Methyl Cellulose Edible Coating on the Shelf life of Fresh Hazelnut
R. Razavi Y. Maghsoudloo M. Ghorbani M. AalamiIntroduction: Today, biodegradable packaging is taken more consideration due to the environmental problems of the synthetic packaging materials. Edible coating is one of the important biodegradable active packaging material and is regarded as a suitable alternative for MoreIntroduction: Today, biodegradable packaging is taken more consideration due to the environmental problems of the synthetic packaging materials. Edible coating is one of the important biodegradable active packaging material and is regarded as a suitable alternative for the synthetic packaging studied. In this research the effects of edible coating based on carboxy methyl cellulose containing thyme was studied with particular reference to moisture absorption, fungal growth and sensory characteristics in coated raw hazelnut. Materials and Methods: The edible coatings were prepared at different concentration levels of carboxy methyl cellulose (0.0, 0.5, & 1.5% W/V) and thyme extracts (0.0, 0.5 & 1% V/V). The mean changes in fungal growth and sensory characteristics were determined for coated and uncoated (control) hazelnut over 21 weeks. The tests were applied in three replications using factorial design based on completely random design. Results: The results of this research showed that non-coated samples had the most moisture absorption, fungal growth and mold development rates. Addition of hydroalcoholic thyme extract to coating solution significantly reduced the fungal growth in coated samples (p≤ 0.05). The results of the sensory tests of the samples indicated that the use of carboxy methyl cellulose coating delayed the softening of the tissues. Conclusion: The use of edible coatings with carboxy methyl cellulose and thyme extract reduced the moisture absorption and mold growth and increased the shelf-life of the coated hazelnuts. Carboxy methyl cellulose, a biodegradable natural biopolymer might be regarded as an alternative to the synthetic packaging. Manuscript profile -
Open Access Article
90 - Optimization of Enzymatic Protein Extraction Conditions and Identification of Microalgae Proteins
M.S. Amiri S.E. Hoseini B. Khayambashi G.H. AsadiIntroduction: The aim of this research work is to optimize the extraction conditions of Scenedesmus Obliquus algae protein by enzymatic and alkaline methods using response surface technique and to investigate the extracted protein’s functional properties. Material MoreIntroduction: The aim of this research work is to optimize the extraction conditions of Scenedesmus Obliquus algae protein by enzymatic and alkaline methods using response surface technique and to investigate the extracted protein’s functional properties. Materials and Methods: Optimization of enzymatic protein extraction using Minitab software with central composite response surface methodolog was designed for enzyme to substrate ratio factors and enzyme’s effective time (cellulose enzymes and multi-enzymes under optimum pH conditions) followed by optimization of the best treatment for the maximum extraction efficiency in the shortest time and finally the extracted proteins were identified by electrophoresis. Results: The results showed that, the higher the enzyme concentration, the higher the extraction rate and the protein extraction efficiency, therefore with an increase in the concentration from 4 to 6 μl/ml, the efficiency of the extraction is increased from 15.28 to 27.87 percent using multienzyme, and it increased from 16.88 to 21.42 percent using cellulase. The optimum conditions calculated at the highest concentration and lowest response time were 4 μg / ml for 2.34 hours. The results obtained from the chemical extraction of samples indicated that, the extraction efficiency was calculated as 19.13 percent. The results of electrophoresis analysis showed that the proteins extracted from this microalga contained 8 protein bands with molecular weight ranging from 20 to 110 kDa. Conclusion: Enzymatic extraction of proteins indicated a better yield as compared to chemical extraction and also considering the economical aspects this method of extraction is suggested. Manuscript profile -
Open Access Article
91 - The Effect of Salep and Carboxy Methyl Cellulose on the Quality of Ketchup
Zeynab Raftani Amiri Amir Mahdi Esmaeili Mazdak AlimiIntroduction: Ketchup is a heterogeneous suspension that is used as a condiment to improve the flavor and color of the food. During storage it changes color, losing consistency with the occurrence of syneresis. In this study the stabilising effect of salep and carboxy m MoreIntroduction: Ketchup is a heterogeneous suspension that is used as a condiment to improve the flavor and color of the food. During storage it changes color, losing consistency with the occurrence of syneresis. In this study the stabilising effect of salep and carboxy methyl cellulose (CMC) on the acidity, pH, color, syneresis, rheological characteristics, microstructure and sensory properties of the ketchup have been examined. Materials and Methods: In this research salep at the level of 0.18, 0.36, 0.45, 0.54, 0.72 and 0.9% with CMC were used in the formulation of ketchup. Color parameters, syneresis, the rheological characteristics, microstructure and sensory properties of the samples were evaluated after one day and thirty days of production. Results: The samples containing 0.45% CMC and 0.45 to 0.22% salep after one day, and samples containing 0.45% CMC after thirty days of production had the least brightness. The samples with 0.9% salep had the maximum red intensity for both periods and samples containing 0.72% and 0.9% salep had the best color score after one day and thirty days of production, respectively. Syneresis in the samples were decreased by the addition of salep in both periods. CMC have a greater impact on the psuedoplastic behavior of ketchup and the highest viscosity was related to the samples containing 0.72% salep. By fitting the power law equation, sample containing 0.45% CMC showed stronger gel structure as compared to other samples containing salep. Microscopic images showed the sample containing 0.72% of salep had more compact and better texture than others. The scores given to the sensory properties were in acceptable range and there were no significant differences between the samples. Conclusion: Salep had a positive effect on the color of ketchup, reduced the syneresis and improved the viscosity. Although CMC had a greater impact on psuedoplastic behavior of ketchup, but microscopic images of the samples confirmed better and more compact structure for samples containing 0.72% salep. Manuscript profile -
Open Access Article
92 - The Synthesis of a New Biofilm Containing Nano-Starch‚ Nano-Cellulose and Garlic Extract, and Assessment of Its Antimicrobial Activity for Use in Food Packaging
F. Hashamdar Ravari S. A. Yasini ArdakaniIntroduction: Antimicrobial packaging is a new trend among various active packaging strategies with greater research focus in recent years. The concomitant use of nanoparticles and antimicrobial materials in food packaging is a new approach. Therefore, this study aimed MoreIntroduction: Antimicrobial packaging is a new trend among various active packaging strategies with greater research focus in recent years. The concomitant use of nanoparticles and antimicrobial materials in food packaging is a new approach. Therefore, this study aimed at making a biofilm based on nanocomposites containing starch and cellulose nanoparticles in addition to garlic extract, which combines degradability and antimicrobial activity. Materials and Methods: Garlic extract was extracted from fresh raw garlic and nanoparticles of cellulose and starch were synthesized biochemically. Scanning electron microscopy was used for characterization of the nanoparticles of cellulose and starch. By adding a mixture of three above materials to polyethylene polymer, a biofilm was prepared and its antimicrobial activity against two species of bacteria, yeast and mold was evaluated alone and in the presence of milk up to 6 weeks. Data were compared using student t-test. A P value of Results: The biofilm showed its greatest antimicrobial effects on E. coli (With an inhibition diameter of approximately 8.5 cm around the biofilm). Antimicrobial properties of biofilm in the presence of contaminated milk (As the packaging model of milk) were significantly higher in comparison to the control without any biofilm. Conclusion: It is possible to have a suitable antimicrobial biofilm by using nanoparticles of starch, cellulose and garlic extract. The findings of the current study suggest a new approach for food packaging industries toward the use of biodegradable active packagings which ultimately lead to quality improvement, food safety and decrease in the amount of waste. Manuscript profile -
Open Access Article
93 - Evaluation of Gluten Free Bread by Using Sorghum Flour and Qodume Shahri and Xanthen Gums
H. Bagheri M. Mohebi A. KochekiIntroduction: The use of gluten free flour is gradually gaining prominence worldwide due tothe nutritional reasons for bread making. The most common disease caused by the protein,prolamin ingestion is celiac and the only effective treatment is to strict the diet free of MoreIntroduction: The use of gluten free flour is gradually gaining prominence worldwide due tothe nutritional reasons for bread making. The most common disease caused by the protein,prolamin ingestion is celiac and the only effective treatment is to strict the diet free ofprolamin.Materials and Methods: This paper examines the effect of two different hydrocolloids,Qodume shahri (QSG) and xanthan gums (XG) at the concentrations of 0, 0.5 and 1% (w/wflour basis) on the rheological properties of dough and sensory characteristics of breadproduced from gluten free sorghum flour. The crumb cell structure was also studied usingdigital image analysis technique.Results: The results showed that the hydrocolloids QSG and XG had positive effects on thebread quality and sensory acceptability of fresh gluten free bread. The results indicated thatthe addition of either of the two cited hydrocolloids could improve the quality of the doughand bread produced.Conclusion: According to the results it might be concluded that Qodume shahri gum actsquite similar to xanthan gum. The work also indicated that the bread produced by wheat flourhas slightly higher acceptability by consumer as compared to the gluten free bread producedbut the production of latter is quite possible. Manuscript profile -
Open Access Article
94 - Effect of Acute L-Arginine Supplementation on Cardiac and Muscle Cell Damage Indices after Exhaustive Exercise Training in Young Karate Players
S. Atashak S. MohammadzadehIntroduction: The aim of this study is to investigate the effect of short-term L-arginine supplementation on lactate dehydrogenase (LDH), creatine kinase (CK) and troponin T (Tnt) enzymes levels after exhaustive exercise in young karate players. Materials and Methods: MoreIntroduction: The aim of this study is to investigate the effect of short-term L-arginine supplementation on lactate dehydrogenase (LDH), creatine kinase (CK) and troponin T (Tnt) enzymes levels after exhaustive exercise in young karate players. Materials and Methods: In semi-experimental study, 18 young karate players randomly assigned in two supplement and placebo groups. Participants in supplement group consumed 3grams daily of L-arginine capsules for seven days, while the placebo group received the same amount of placebo. All subjects performed an exhaustive aerobic exercise after seven days supplementation. Venous blood samples were collected at four stages; 1: pre supplementation, 2: After the end of the supplementation period and pre exercise, 3: Immediately post exercise and 4: 24 hours after exercise. Data was analyzed by repeated measure ANOVA and Bonferroni post-hoc test at α ≤ 0.05. Results: The results of the study indicated that the increase of CK, was significantly higher (p<0/05) at the immediately and 24 hours after exercise in the placebo group as compared to the L-arginine group. However, the LDH and Tnt levels significantly increases in both placebo and supplement group at the immediately and 24 hours after exhaustive exercise (p<0/05). Conclusion: In general, it can be concluded that short-term L-arginine supplementation can ameliorate the muscle cell damage induced to exhaustive exercise by prevention of the CK increase in young athletes. Manuscript profile -
Open Access Article
95 - Investigation of the Physicochemical and Sensory Characteristics of Low-Fat Yogurt Containing Long-Chain Inulin and Carboxymethyl Cellulose
M. Karim B. Naderi M. Mirzaei N. SanjabiIntroduction: In preparation of set yogurt, the aim is not only to provide a product with optimal spoonability, but also to obtain an attractive appearance, softness and texture free of coarse particles with least synersis. In this study the effect of long-chain inulin MoreIntroduction: In preparation of set yogurt, the aim is not only to provide a product with optimal spoonability, but also to obtain an attractive appearance, softness and texture free of coarse particles with least synersis. In this study the effect of long-chain inulin (Since the long-chain inulin has nutritional properties) and carboxymethyl cellulose on the physicochemical and sensory characteristics of low fat yogurt during 15 days have been investigated in order to determine the most appropriate treatment for future studies. Materials and Methods: In this study, the experiment was designed with the use of two independent variables of long-chain inulin (DP≥22) and carboxymethyl cellulose in the form of 5 treatments of yogurt. Tests concerned with pH, acidity, synersis, water holding capacity, viscosity and colorimetric were carried out 24 hours, 5 and 7 days after the preparation of the samples. Results: The results showed that there were no significant differences concerning acidity, pH, L* and a* between control and other treatments containing carboxymethyl cellulose and inulin but synersis decreased, water holding capacity and viscosity increased and sensory properties (except odor) improved. Conclusion: According to the results, sample containing 0.75% inulin and 0.25% carboxymethyl cellulose and sample containing 0.5% inulin and 0.5% carboxymethyl cellulose were introduced as the chosen prebiotic and functional yoghurt samples with superior physicochemical and sensory characteristics. Manuscript profile -
Open Access Article
96 - Preparation of Composite Films from Quince Seed Mucilage and Nanocrystalline Cellulose and Studying their Properties
T. Bayzavi S. Ansari N. DaneshIntroduction: Today, different methods are being used to improve the properties of edible films; one of the most effective and commonly used ones is using nanometer-sized fillers and the production of polymer nanocomposites. The objective of the present study is to prod MoreIntroduction: Today, different methods are being used to improve the properties of edible films; one of the most effective and commonly used ones is using nanometer-sized fillers and the production of polymer nanocomposites. The objective of the present study is to produce quince seed-based nanocomposite film reinforced with nanocrystalline cellulose and to study the properties of the resulting composite film. Materials and Methods: In the first step, the quince seed mucilage was extracted and then, with different concentrations of nanocrystals cellulose (NCC) (3, 5, and 7%) and 35% (w/w) glycerol as plasticizer the nanocomposite film was produced by molding method. Then the physical, mechanical, barrier, thermal and structural properties of the films were examined. Results: Addition of nanocrystals increased the thickness of resulting films but decreased their moisture content, water solubility and water vapor permeability (WVP) to 7.2%, 29.3% and 5.6% when using 7% nanocrystal cellulose. Increasing of nanocrystals concentration in films resulted in an increase in a* and b* and a decrease in L*. Incorporation of nanocrystals also improved the mechanical properties of quince seed gum-based films including tensile strength and young module, whereas elongation at break was not significant. The glass transition temperature of films also was increased by the addition of nanocrystals which was determined by means of differential scanning calorimetry. FT-IR spectra of samples also approved the interaction between nanocrystals and quince seed gum. Conclusion: The produced films exhibited good physical properties, reduced WVP, and enhanced mechanical properties, which are the main properties required for packaging applications. Manuscript profile -
Open Access Article
97 - The Effect of Carboxymethyl Cellulose Film Containing Essential Oils of Cinnamon and Cloves on the Shelf Life of Refrigerated Beef
R. Mahjoob E. Ataye SalehiIntroduction: Fresh foods that have been subjected to least processing conditions have become quite popular. The application of edible films and biodegradable materials is a new method to maintain some food products. Materials and Methods: In this study the impact of di MoreIntroduction: Fresh foods that have been subjected to least processing conditions have become quite popular. The application of edible films and biodegradable materials is a new method to maintain some food products. Materials and Methods: In this study the impact of different concentrations of essential oil of cinnamon and cloves (0, 0.2, 0.3 and 0.4 %) is employed on the film of carboxy methyl cellulose. The tests were concerned with coated meat on 0, 3rd, 6th, 9th and twelfth days. Results: The samples coated with different films during this study were compared to the control. The coated samples showed lower pH, total volatile nitrogen, peroxide value, reactive thiobarbituric acid and total microbial count (p<0.05). Conclusion: The results indicated that the packed meat with carboxy methyl cellulose and different concentrations of cinnamon and cloves essential oils had effective results concerned with chemical spoilage of the product. The application of 0.3% of essential oil might be regarded as an optimum concentration for the essential oil. Manuscript profile -
Open Access Article
98 - Effect of Using Hydroxy Propyl Methyl Cellulose With Extract of Royal Oil (Lepidium sativum) in Reducing Oil Absorption and Quality of Fried Common Carp Fish Fillet (Cyprinus carpio(
Z. Latifi z. Ghafuri Sh. Manochehri S. Khaki Arani M. Daneshniya L. Roozbeh Nasiraie S. JafarianIntroduction: In recent years due to the health consumers are attracted to meat products with decreased levels of fat, cholesterol and energy value. Therefore, in the present study, the feasibility of producing superfine fried fish using hydroxy propyl methyl cellulose MoreIntroduction: In recent years due to the health consumers are attracted to meat products with decreased levels of fat, cholesterol and energy value. Therefore, in the present study, the feasibility of producing superfine fried fish using hydroxy propyl methyl cellulose coated and Lepidium sativum extract was studied. Materials and Methods: Control samples (without coated), treatment 2: hydroxy propyl methyl cellulose, treatment 3: Hydroxy propyl methyl cellulose with Lepidium sativum extract of 500 ppm, treatment 4: hydroxy propyl methyl cellulose with Lepidium sativum extract of 1000 ppm and treatment 5: hydroxy propyl methyl cellulose with Lepidium sativum extract of 2000 ppm were prepared and the oil absorption, moisture content, peroxide value, thiobarbituric acid and Sensory analysis of fried fish produced were evaluated. Results: The results of physicochemical test showed that hydroxy propyl methyl cellulose with Lepidium sativum extract increased the moisture content and reduced the absorption of oil compared to the control treatment, and was more effective to delay lipid oxidation in fried fish fillet by decreasing peroxide and thiobarbituric values. The best results in relation to these parameters were observed in treatment 5 and then in treatment 4. Sensory score of treatment 4 was higher than the sensory rating of treatment 5. Conclusion: The results of this study indicated that hydroxypropylmethyl cellulose and 1000 ppm concentration of Royal extract can enhance the nutritional value of fish fillet by reducing the oil absorbtion and intreasing the moisture content of fried fish. Manuscript profile -
Open Access Article
99 - Preparation and Characterization of Micro Cellulose Moisture Absorbent Pad for Food Packaging Applications
Zahra Ebadi Behjat TajeddinIn this research, the natural film based on starch and cellulose on a micro-scale was produced and its properties were investigated in terms of sheeting ability to absorb moisture in food packaging. For this purpose, ground cellulose fibers with 60-micrometer mesh were MoreIn this research, the natural film based on starch and cellulose on a micro-scale was produced and its properties were investigated in terms of sheeting ability to absorb moisture in food packaging. For this purpose, ground cellulose fibers with 60-micrometer mesh were dissolved in 1% acetic acid solvent, starch, and glycerol. The resulting solution was converted into a film by casting the evaporation method and drying at ambient temperature. The properties of biodegradable biofilms such as swelling degree (SD), water vapor permeability (WVP), tensile strength (TS), and elongation at break (EB) were evaluated at various thicknesses and times. Results indicated that the maximum amount of SD of biopolymer (5.91) was obtained in thickness group 1 (> 0.1mm) and during 30 min of storage. The relatively high strength of the micro cellulose (MC) film was significant (6.78 ± 0.76 N) and its permeability increased by increasing the thickness of the biofilm. The results showed that due to the hydration ability and strength of the MC film can be used as a moisture-absorbent bio pad for food packaging purposes. Manuscript profile -
Open Access Article
100 - Evaluation of Additional Carboxy Methyl Cellulose and k-Carrageenan Gums on the Qualitative Properties of Gluten- Free Toast Breads
S. Movahed M. Mirzaei H. Ahmadi Chenarbon -
Open Access Article
101 - The Effects of Adding Xanthan and Carboxy Methyl Cellulose on Cooking and Sensory Characteristics of Soya Burger
A. Basati S. E. Hosseini -
Open Access Article
102 - Effects of Carboxymethyl Cellulose, Pectin and Guar on Dough Rheology and Quality of Toast Breads
E. Karbala’e Husseina S. Movahhed A.R. Shahab Lavasani -
Open Access Article
103 - Optimization of Single Cell Protein Production by Aspergillus niger Using Taguchi Approach
F. Ardestani F. Alishahi -
Open Access Article
104 - Quantity and quality evaluation of the Cellulose Nanocrystalline Production from Date Palms (Phoenix Dactylifera L.) by Hydrolysis Method
Ali khaziri Hassan Zaki Dizaji Mohammad Reza Fathi EmadabadiBackground and Objective: Cellulose in the wastes and losses of the agricultural branch can be a good source to produce cellulose-based valuable materials in the industry. Cellulose and nanocrystalline cellulose are extracted and produced by various processes from diffe MoreBackground and Objective: Cellulose in the wastes and losses of the agricultural branch can be a good source to produce cellulose-based valuable materials in the industry. Cellulose and nanocrystalline cellulose are extracted and produced by various processes from different natural sources. The subject of this study was to investigate the conditions of acid hydrolysis on the structure of cellulose nanocrystals produced from palm waste. Material and Methodology: In this research, cellulose was first extracted from Date palm leaves, and it was then converted to the cellulose nanocrystal by acid hydrolysis of the nanocrystal cellulose. In this research, the effect of 3 temperature parameters (at 30, 45 and 60 ° C) and 3 time (at 45, 60 and 120 minutes on three levels) on the quality and quantity of nanocrystals from palm tree leaves were investigated. Several experiments with infrared spectroscopy (FTIR), X-ray diffraction (XRD), scanning electron microscopy (SEM) and particle size measurement (PSA) techniques were used to analyze qualitative and quantitative qualities such as factor groups, morphology, diameter distribution and shape Nanocrystals have been studied. Findings: The results showed that more severe treatments produce smaller Nano-crystals. The results of the Particle Measurement (PSA) showed that most extractive particles have dimensions ranging from 5 to 100 nanometers and are mostly 30 nm. Also, the results (XRD) showed that extractive nanocellulose had a purity of between 70 and 80 percent. In this study, the time of 60 minutes and 60 Celsius temperatures were identified as the best factors among similar factors. In this treatment, 50% of particles have a mean diameter of 1.37 nm. The maximum and minimum diameter of the observed particles was 6.34 and 0.41 nm, respectively. Also, the results of cellulose extraction from palm leaf showed that increasing the temperature in the lignification and coloring step increases the purity of the extracellular cellulose. In addition, the increase in temperature resulted in a decrease in the amount of cellulose produced, possibly due to the increased effect of chemical treatments and cellulose degradation. Discussion and conclusion: The results showed that if the extracted cellulose nanocrystals were transformed into a network, they had the potential to be used in nano filters and nano-scaffolds. Manuscript profile -
Open Access Article
105 - Efficiency of Iron Nanoparticles and Cellulosic Wastes for Reclamation of Lead Contaminated Soil and Oak Seedling Establishments
Mahya Tafazoli Seyed Mohammad Hojjati Pourya Biparva Yahya Kooch Norbert Lamersdorf Background and Objective: Due to the contamination of northern forests with heavy metals by activities such as mining, the aim of this study was to use zero-valent iron-nano-particles and cellulosic-waste for reclamation of soil contaminated with lead and to esta More Background and Objective: Due to the contamination of northern forests with heavy metals by activities such as mining, the aim of this study was to use zero-valent iron-nano-particles and cellulosic-waste for reclamation of soil contaminated with lead and to establish oak seedlings. Method: One-year-old oak seedlings were planted in plastic-pots filled with nursery soil in March-2014. Lead was added to the pots at concentrations of 0, 100, 200, 300 (mgkg-1) using lead-nitrate solution. Cellulosic-waste with levels of 0, 10% (W1), 20 %( W2) and 30 %( W2) was added to the pots at the same time of planting. Zero-valent iron-nanoparticles with levels of 0, 1(N1), 2(N2) and 3(N3) mgkg-1 was injected into the soil. The diameter, height, dry weight, bioavailable concentration of lead and amendments efficiency was measured at the end of the growing season. Findings: With increasing levels of amendments (from 10 to 30% for cellulosic-waste and from 1 to 3 mg kg-1 for iron-nanoparticles), an increasing trend in seedlings biomass was observed for all levels of contamination. The highest efficiency for all contamination levels was observed in highest level of each amendment. The efficiency of N3 treatment for Pb 100, Pb 200 and Pb 300 was 79.5, 84.4 and 67.8%, respectively and the efficiency of W3 treatment was 55.6, 74.9 and 63.1%, respectively. Discussion and Conclusion: The use of zero-valent nano-particles had a better efficiency than cellulosic-waste to reduce the bioavailability of lead; therefore, planting native species and using such amendments in planting holes can help the reforestation of contaminated areas. Manuscript profile -
Open Access Article
106 - Synthesis and Investigation of Open Cell Polyurethane Sponge-Silver Oxide Nanocomposite Efficacy in Water Disinfection
H.R. Ashjari-Basmenj M. S. Seyed Dorraji M. H. Rasoulifard M. Moghadam Shima Sheikh MohammadiBackground and Objective: The use of nanotechnology is one of the most important and effective methods for microbial enumeration and water treatment. Dispersing the silver oxide nanoparticles in different polymer matrixes (in particular, open cell polyurethane sponge ma MoreBackground and Objective: The use of nanotechnology is one of the most important and effective methods for microbial enumeration and water treatment. Dispersing the silver oxide nanoparticles in different polymer matrixes (in particular, open cell polyurethane sponge matrixes) can be an efficient way in the water treatment and microbial enumeration. Method: In the present study, the silver oxide nanoparticles were dispersed into the open cell polyurethane sponge raw materials and then, the polyurethane sponge was synthesized using a One-shot method. In addition, the usability of synthesized polyurethane sponge as an antibacterial agent for water disinfection was investigated by using "plate counting" (reducing the bacteria number in contaminated water over time) method. Also the 0.5 McFarland (1.5*108 CFU/ml) suspensions diluted with biomass serum (1:2) of Escherichia coli and Staphylococcus aureus were used as contaminated water. Ultimately, the structural properties of synthetic sponges were investigated using Scanning Electron Microscopy (SEM) and Fourier Transform Infrared Spectroscopy (FT-IR). Findings: The end of 12 hours has been recognized the antimicrobial activities of the prepared sponges against Escherichia coli and Staphylococcus are acceptable. The results indicated that the antimicrobial activities of the prepared sponges against Escherichia coli and Staphylococcus are acceptable. The results also showed that nanocomposite in certain conditions after 6 and 8 hours prevented the growth of Staphylococcus aureus and Escherichia coli bacteria, respectively. So that after 6 and 8 hours contact with the nanocomposite, the number of Staphylococcus aureus and Escherichia coli bacteria in contaminated water was reduced by 100% (t0=50*106 CFU/ml, t6=0*106CFU/ml) and 30% (t0=50*106 CFU/ml, t8=35*106CFU/ml), respectively. Discussion and conclusion: Development and utilization of antimicrobial sponges in water treatment processes can reduce the use of chemical agents to infection control. Silver oxide nanoparticles, due to the high surface-to-volume ratio and interactions with the bacterial cell walls, cause damage to the bacterial cell walls and destroy the cellular structure of the bacteria. Manuscript profile -
Open Access Article
107 - Investigation on Application of Simultaneous UV Irradiation Ultrafiltration of Extracellular Polymeric Substances Extracted from Membrane Bioreactor and Its Effect on PVDF/TiO2 Membrane Mitigation
Maryam Tavakolmoghadam Seyed Mohammad Ali SafaviBackground and Objective: The object of this study is to investigate the effect of surface modification of Polyvinylidene fluoride (PVDF) membrane on filtration performance and reduction of fouling in membrane bioreactors (MBRs). This study was done based on the photoca MoreBackground and Objective: The object of this study is to investigate the effect of surface modification of Polyvinylidene fluoride (PVDF) membrane on filtration performance and reduction of fouling in membrane bioreactors (MBRs). This study was done based on the photocatalytic properties of TiO2 nanoparticles under ultraviolet light irradiation and to assess the effect of reducing membrane fouling in real EPS extraction of submerged membrane bioreactor as the main foulant. Method: Considering photocatalytic properties of TiO2 nanoparticles under ultraviolet light irradiation, PVDF/TiO2 performance in filtration of extracellular polymeric substances extracted (EPS) from membrane bioreactor which was used for oil refinery wastewater treatment and has been evaluated and compared with PVDF membrane without TiO2 nanoparticles. Findings: The results showed improvement of permeation flux and flux recovery ratio of nano-composite PVDF/TiO2 under UV radiation due to membrane super hydrophilicity which results in irreversible membrane resistance of EPS UV irradiated to 0.36×1012 m-1 and PVDF/TiO2 membrane total resistance reduction to about 44% comparing to pure PVDF membrane. According to the results by ultrafiltration combined with UV, the flux recovery of about 90% for PVDF/TiO2 membrane can be achieved. Discussion and Conclusions: Considering EPS as the main foulant of refinery MBRs, simultaneous UV irradiation ultrafiltration of EPS extracted from membrane bioreactor by PVDF/TiO2 membranes can be considered as an effective approached in fouling reduction research in future. Manuscript profile -
Open Access Article
108 - Using Conocarpus erectus Tree pruning Residue for Paper product
ahmad azizi mossello Pejman Rezayati-Charani ّFarshid MehriBackground and Objective: Due to raw materials shortage for lignocellulosic industries, and cultivating Conocarpus erectus tree in the country due to its significant growth rate and adaptation to the country's climatic conditions, the use of its pruning residues can be MoreBackground and Objective: Due to raw materials shortage for lignocellulosic industries, and cultivating Conocarpus erectus tree in the country due to its significant growth rate and adaptation to the country's climatic conditions, the use of its pruning residues can be considered as an alternative raw material.Material and Methodology: The Conocarpus erectus pruning residues were divided into three groups: 1- leaf, 2- branch, and 3- branch-leaf. Then the chemical composition and morphological properties were measured. Afterward, these residues were cooked by soda method and from the obtained pulps, laboratory handmade papers were made and to end, the properties of resulting pulps and the handmade papers were evaluated.Findings: The results showed that different parts of the Conocarpus residues have completely different properties, so that the leaves with the highest content of extractives, lignin and ash and lowest amount of cellulose and hemicellulose gave pulp with lowest screened yield and highest kappa number that was not suitable for paper production due to very low freeness and high drainage time. In contrast, the branch with the highest amount of cellulose and hemicellulose and lowest amount extractive materials, lignin and ash produced pulp with highest screened yield, freeness and lowest kappa number and drainage time. Also, in Compared to leaf- branch, pulp from branch produced paper with higher thickness, light scattering coefficient and tear but lower tensile and appear density.Discussion and Conclusion: In general, leaves and branches residue of Conocarpus compared to other lignocellulosic materials such as wheat straw and bagasse, which is widely used in the pulp and paper industry, due to qualitative properties reasons are not suitable in pure form for use in pulp and paper industries but are recommended to evaluation as the mixing with the recycled pulp. Manuscript profile -
Open Access Article
109 - Preparation of Modified Nanocellulose with 5-Br-PADAP for Preconcentration and Determination of Trace Amounts of Cobalt Ions in Natural Water Samples
Sekyneh ganji-jouybari Ali Mirabi Ali Shokuhi radBackground and Objective: Separation and determination of trace amounts of cobalt ions in real samples due to their toxicity to humans is very important. In the present study, a nanocellulose was synthesized by the acid hydrolysis and then modified with 2-(5-bromo-2-pyr MoreBackground and Objective: Separation and determination of trace amounts of cobalt ions in real samples due to their toxicity to humans is very important. In the present study, a nanocellulose was synthesized by the acid hydrolysis and then modified with 2-(5-bromo-2-pyridylazo)-5-diethylamino phenol (5-Br-PADAP). The size of cellulose nanofibers was determined using transmission electron microscope (TEM). After modification of the nano-sorbent with the 5-Br-PADAP, the thermogravimetric analysis (TGA) of the modified nanocomposite was carried out, and the BET technique was used to determine the surface area of the nano-sorbent before and after modification. In the present work, the aim is to modify the surface of nanocellulose with ligand of 5-Br-PADAP to use them to extraction and pre-concentration of trace amounts of cobalt ions before determination it by flame atomic absorption spectroscopy in real samples.Material and Methodology: Certain volume of cobalt ion into the test tube containing the modified nanosorbent was Poured and buffer solution with pH = 9 was added and place it in a shaker and finally centrifuged for 15 minutes and then discard the top solution and 1 mL HCl was added to recover cobalt ions and placed in a shaker for 10 minutes and then centrifuged, and the absorption of the supernatant was determined by FAAS. The results showed that the modified nanocellulose is very sensitive and selective towards the determination of cobalt ions which could be affected by several parameters such as pH, adsorbent amount, sample volume, extraction time, and type of eluetion.Findings: The calibration curve is linear in the range of 10-500 ng/mL, and the detection limit and the relative standard deviation (RSD) are calculated to be 4.3 ng/mL and 1.8 %, respectively, that result in a high preconcentration and enrichment factor.Discussion and Conclusions: By using the flame atomic absorption spectrometry and applying the standard addition method, the proposed method was used to determination of the trace amounts of cobalt ions in the natural water samples such as seawater, river water, well water, lake water and tap water, with satisfactory results. Manuscript profile -
Open Access Article
110 - Investigation the amount of Zinc pollution on soil resources and the feasibility of its removal with Phragmites australis plant using its extraction cellulose in the greenhouse conditions
Malihe Amini Atena Naeimi Hana EtemadiBackground & Objective: Heavy metals cases are threatening the health of ecosystems. Accumulation of metals in the soil allows them to plant crops and thus increases the risk of agriculture crops health. The goal of this research was conducted to evaluate zinc stres MoreBackground & Objective: Heavy metals cases are threatening the health of ecosystems. Accumulation of metals in the soil allows them to plant crops and thus increases the risk of agriculture crops health. The goal of this research was conducted to evaluate zinc stress resistance for Pharagmites australis in greenhouse conditions.Material and Methodology: Experimental design was performed in an entirely randomized plan having two factors and three replications, 2016 at University of Jiroft. Digestion and preparation of samples were done by dry burning method and then Zinc concentration was measured by atomic absorption.Findings: Greenhouse experiments results showed that with increasing in metal concentration treatments, its absorbing with shoot and root were increased. However, impressive accumulation of zinc was in root and its translocation and accumulation in shoot has been reported much less.Discussion & Conclusions: With absorb and accumulate of metals in root, ability of plant growth was decreased with changes in physiological characteristics. Results of regression analysis showed concentration increasing of zinc in P. australis organs under these metal stress condition were fitted as a quadratic function with R2 >90 (p<0.01). In summary results of this research show high relatively resistant of P. australis to zinc stress as necessary metal in plants, high accumulation capacity for metal in its root organ and low heavy metal translocation factor. Manuscript profile -
Open Access Article
111 - Land use changes predicition in Zagros forest areas based on Markov Chain Model
Ali Qaderian Naser Ahmadi SaniBackground and Objective: Today, due to increasing population growth and land use changes and its impact on the environment, monitoring and modeling land use changes is one of the main prerequisites for optimum use of land and achieving sustainable development. The purp MoreBackground and Objective: Today, due to increasing population growth and land use changes and its impact on the environment, monitoring and modeling land use changes is one of the main prerequisites for optimum use of land and achieving sustainable development. The purpose of this study was to evaluate and predict the spatial and temporal dynamics of land use in the county of Sardasht, in order to obtain basic information for planning in line with sustainable forest management.Material and Methodology: Data from the Landsat 7 images (+ETM) 2003, and Landsat 8 (OLI) 2015 were analyzed. The Maximum Likelihood algorithm has been used to mapping the land use for the years. The analysis of the change dynamics using traditional Markov Chain and Cellular Automata was predicted for the next 25 years.Findings: The overall accuracy of classified images in 2003 and 2015 was 89% and 94%, respectively, and the Kappa coefficient was 0.87 and 0.92. The results showed that during the period, bout 7% of the forest area has decreased and the agricultural lands has increased by 72%. According to the Markov transmission probability matrix the classes most affected by these changes is the forests and rangelands that changed to agricultural and residential.Discussion and Conclusion: Changes in the extent of forests until 2040 show that the area of forests will decrease continuously. The results of current study could provide quantitative information, which represents a base for assessing the sustainability in the management of Zagros forest ecosystems and for taking actions to mitigate degradation. Manuscript profile -
Open Access Article
112 - Ranking of Indicators of Green Supply Chain Management in the Cellulose Industry Using EDAS-SEM Method
majid nili ahmadabadi omidali adeli ,mohammad cheraghiBackground and Objective: Cellulose industries are closely related to forests and natural resources, and on the other hand, the chemicals used in them are sometimes transferred to nature. Therefore, they can affect the environment in two ways and therefore have an urgen MoreBackground and Objective: Cellulose industries are closely related to forests and natural resources, and on the other hand, the chemicals used in them are sometimes transferred to nature. Therefore, they can affect the environment in two ways and therefore have an urgent need for management with a green approach, especially in the field of supply chain. Achieving this is possible by finding the most effective factors in implementing green supply chain management in this industry, which has been done in this research. In previous similar studies, the weight of the same factors has often been considered, and in addition, the weight of the interviewees has been considered the same when collecting data. In this paper, both problems have been solved by using EDAS-SEM methods and a more valid ranking of the components of green supply chain management in the cellulose industry has been presented.To provide a green supply chain management model in the cellulose industry, including transparent factors and accurate weights so that it can be used to measure the performance of managers in this area and to suggest the most effective factors for future promotion to managers.Material and Methodology: This research is qualitative and survey in how to collect data and quantitative in processing them. In terms of practical purpose and in terms of method, it is mixed. Modeling and analysis methods include entropy, EDAS, SEM. The statistical population is 63 managers of Qom cellulose production industries, for whom a questionnaire was sent in 2019, and 55 were completed. Therefore, sampling method, sample is available. Data collection tool is a questionnaire and data analysis tool is confirmatory factor analysis with partial least squares approach and SmartPLS3 software. Excel was used for entropy and EDAS calculations.Findings: The most important indicators of green supply chain performance in Qom cellulose products industries are selecting suppliers with environmental criteria, determining environmental requirements for purchasing items and auditing compliance with environmental regulations. Also, the weight of managers varies according to the characteristics of the elites. These findings can be generalized to other cellulose industries.Discussion and Conclusion: The proposed model can be used for a better future in the management of the green supply chain of cellulose industries by evaluating the performance of managers in senior and middle levels at the organizational and unit levels. The achievements of this research can also be used to identify the most important factors at each level and allocate future resources to them. Manuscript profile -
Open Access Article
113 - Microbial fuel cell: a strategy for bioremediation and energy production
Mehran Jafari Samaneh Sedighi KhavidakBackground and Objective: Application of microbial fuel cells (MFC) is a new method for wastewater treatment and environmentally friendly energy production. This technology converts the chemical energy derived from metabolic activity of living organisms into electrical MoreBackground and Objective: Application of microbial fuel cells (MFC) is a new method for wastewater treatment and environmentally friendly energy production. This technology converts the chemical energy derived from metabolic activity of living organisms into electrical energy. Method: A sample of raw wastewater was prepared as a source of microbial fuel cell substrate from the refinery of Yazd city. This study was carried out using a two-compartment bioreactor with wastewater as substrate and microbial flora. The containers were made of glass with a volume of 550 cc. In the anode chamber, under the anaerobic conditions, the wastewater was catalyzed by microbial flora. In the cathode chamber, potassium phosphate buffer was used to maintain the pH of the solution. The positive ions transferring from anode to cathode was done by positive salt bridge system. Findings: The findings showed that the maximum voltage of 1 V was produced during the early days in this reactor. Then gradually the amount of voltage was reduced and wastewater samples were refined to some extent. The highest rate of produced flow was 248 μA, and then the flow rate was decreased. Therefore, the dual role of the reactor in electricity production and wastewater treatment can be explained. Discussion and Conclusion: In this study, wastewater treatment and also electricity production could be performed using a microbial fuel cell based on salt bridge. Manuscript profile -
Open Access Article
114 - Land use / land cover change modelling using Markov chain and Cellular Automata (Case study: Hamedan province)
Jalil Imani Harsini Mohammad kaboli Jahangir Feghhi Ali TaherzadehBackground and Objective: The extent of spread and source degradation would be determined using prediction of land use/ land cover changes. In this way these changes would be guided in the right directions. The aim of this study is modeling the process of land use / lan MoreBackground and Objective: The extent of spread and source degradation would be determined using prediction of land use/ land cover changes. In this way these changes would be guided in the right directions. The aim of this study is modeling the process of land use / land cover changes of Hamedan province using Landsat TM satellite image of 1989 and IRS LISS III image of 2008. Method: After running the necessary corrections, land use/ land cover maps of the study area in the past two years were obtained using supervised classification with maximum likelihood algorithm. Then probability matrix of land use transition (to each other) were calculated using Markov chain with respect to land use/ land cover map. In the next step, Cellular Automata method was used to geo specified these changes. Findings: Finally land use/ land cover map of Hamedan province for 19 years later (2024) was obtained and the area of each land use/ land cover was calculated. Discussion and Counclusion: The results of this research shows that natural land use/ land covers will be decreased and transmited to human land uses in future. These changes are conceivable due to population growth and increasing human needs to exploit the nature; but this process should be considered to exploit the natural resources in a sustainable manner to avoid severe consequences in future. Manuscript profile -
Open Access Article
115 - A new design algorithm for modeling and comparative evaluation of compound regenerative fuel cell (RFC) systems
Hossein Ghadamian Farideh Atabi Hassnali OzgoliThe results of calculation, modeling and engineering design of RFCs reveal that energy carrier change, from electrical to cold chemical combustion in the fuel cell section, is considered as an internal energy production and significantly increases the produced energy in MoreThe results of calculation, modeling and engineering design of RFCs reveal that energy carrier change, from electrical to cold chemical combustion in the fuel cell section, is considered as an internal energy production and significantly increases the produced energy intensity rate and the performance coefficient of the system. By connecting photovoltaic system to electrolyze/fuel cell units and using the energy produced in photovoltaic section, the internal energy generation for a multiple case system with 1 kW capacity will be 2.302 kW, and the energy produced in the RFC complex will increase so that the efficiency of the total integrated system will be 29.45%. In this article, the general performance of the system and its related sub-systems together with capacity studies has been investigated. Then, using electrolyze formulation, fuel cell, and photovoltaic cells separately, modeling has been carried out with non-linear algorithms, and system integration has been done with GAMS software. Also, a step-by-step approach to the calculation and engineering design of the RFC is presented. Manuscript profile -
Open Access Article
116 - The first report on the identification of planktonic communities from Sarbaz River in Sistan and Baluchestan Province
Mahmood Sinaei Ashrafali Hosseini Mehdi BlookiBackground and Objective: Due to importance of Sarbaz River in the Sistan and baloochestan province, study about environmental status of this river especially plankton community have so valuable and importance.So, this research was conducted to study plankton community MoreBackground and Objective: Due to importance of Sarbaz River in the Sistan and baloochestan province, study about environmental status of this river especially plankton community have so valuable and importance.So, this research was conducted to study plankton community of Sarbaz River. Method: Sampling was carried out monthly in the ten sampling sites (Kajdar, Bandan, Hit, Firooz abad, Pole jakigoor, Ab nemaye Sade pishin, Pole kahirborz, Shir govaz, Jor) through Sarbaz River. The collected samples were fixed in 10% formalin and brought to the laboratory for plankton analysis Findings: Generally, ten species of phytoplankton (Bacillarphyceae) were identified in the all sampling sites. The Navicula with five species was more frequent than other phytoplankton species. Three groups of zooplankton including crustacean, rotifer and ciliates were identified in the all sampling sites. We have identified two groups of crustacean: Cyclops and daphnia. The frequent species among zooplankton were ciliates. This species have found in the all sapling sites and times. We have found negative relationship between diversity and frequency of crustacean. Crustacean with higher diversity have lower frequency. Conclusion: Studying plankton community in the Sarbaz river have shown that this environment have very low plankton diversity and frequency. Manuscript profile -
Open Access Article
117 - مسأله تخصیص موعد تحویل و زمانبندی بههنگام در سلولهای رباتیک جریان کارگاهی ترکیبی بلوکهشده با چندین روبات و هزینه تحویل دستهای
جواد رضائیان نگار درخشان ایرج مهدوی رضا علیزاده فروتندر این مقاله، مسأله زمانبندی بههنگام با تحویل دستهای و تخصیص موعد تحویل برای سلولهای رباتیک جریان کارگاهی ترکیبی در نظر گرفته شده است. یک مدل برنامهریزی خطی عدد صحیح مختلط، برای تعیین توالی کارها و حرکات رباتها ارائه شده است. دو الگوریتم فراابتکاری شامل سیستم ایمنی Moreدر این مقاله، مسأله زمانبندی بههنگام با تحویل دستهای و تخصیص موعد تحویل برای سلولهای رباتیک جریان کارگاهی ترکیبی در نظر گرفته شده است. یک مدل برنامهریزی خطی عدد صحیح مختلط، برای تعیین توالی کارها و حرکات رباتها ارائه شده است. دو الگوریتم فراابتکاری شامل سیستم ایمنی مصنوعی و جستجوی ممنوعه پیشنهاد شده است. نتایج نشان میدهند الگوریتم سیستم ایمنی مصنوعی برای این مسأله به خوبی عمل میکند. Manuscript profile -
Open Access Article
118 - Mathematical Modeling of Micropolar Blood Flow in a Stenosed Artery Under the Body Acceleration and Magnetic Field
AR. Haghighi N. Aliashrafi M. Kiyasatfar -
Open Access Article
119 - On an Efficient Family with Memory with High Order of Convergence for Solving Nonlinear Equations
V. Torkashvand M. Kazemi -
Open Access Article
120 - Two new three and four parametric with memory methods for solving nonlinear equations
T. Lotfi P. Assari -
Open Access Article
121 - MHD rotating heat and mass transfer free convective flow past an exponentially accelerated isothermal plate with fluctuating mass diffusion
K. Jonah ‎Philliph‎ M. C. ‎Raju‎ A. J. Chamkha‎ S. V. K. Varma -
Open Access Article
122 - Simulation of the Spatial Pattern of Land Use Change in the City of Gachsaran Using Cellular Automata Model
Mohsen Derakhsh Soheil Sobhan ArdakaniBackground and Objective: Simulation of land-use change is very useful for governmental plans and policies. A number of models including system models, Markov chains, the CLUES-S and the SLEUTH have been developed for the simulation of land-use change. Among them, cellu MoreBackground and Objective: Simulation of land-use change is very useful for governmental plans and policies. A number of models including system models, Markov chains, the CLUES-S and the SLEUTH have been developed for the simulation of land-use change. Among them, cellular automata (CA) modeling is widely applied to simulate complicated dynamic systems. In this regard, information on land use and also land cover and possibilities for their optimal use is essential for the selection, planning and implementation of land use schemes to meet the increasing demands for basic human needs and welfare.Therefore, this study was conducted to forecasting and modeling of urban development of city of Gachsaran using a CA Model for 2044. Method: In this descriptive study, the land use mapping, a predominantly cloud-free image of Landsat Multispectral Scanner (MSS, 1972), Landsat Thematic Mapper (TM, 1986), Landsat Enhanced Thematic Mapper (ETM+, 1999), and Operational Land Imager (OLI, 2015) were used to the modeling of land-use changes of the study area between the periods 1972 to 2015, and also to the simulation of land-use changes of city of Gachsaran in 2044. Findings: Based on the results obtained, the increasing growth of urban use over time, particularly in the northern part of the city, and the decline in natural and ecological land use, especially agricultural land were observed. Also, the results clearly suggest that the development process of the city of Gachsaran during the recent years did not follow a proper pattern and, especially the unbalanced growth could be observed in the western part of the city. On the other hand, according to the forecasting of model output, in 2044 about 70% of the extent of the study area, will be dedicated to urban use. Discussion and Conclusion: In general, it can be admitted that the CA model has a high ability in simulating the urban development process and can effectively be used to study the urban dynamic, especially in rapidly growing cities. Manuscript profile -
Open Access Article
123 - New Method of Water and Wastewater Treatment Using Electron Beams
seyed mohammad mousavianRelease of several types of pollutants to the environment and implementation of ever strict environmental rules and the inability of traditional treatment methods to completely eliminate or reduce the pollutants to a standards level lead to study and develop of new trea MoreRelease of several types of pollutants to the environment and implementation of ever strict environmental rules and the inability of traditional treatment methods to completely eliminate or reduce the pollutants to a standards level lead to study and develop of new treatment processes such as the electron beams. The electron beams irradiation to water and wastewater resulting generation of reducing and oxidizing species (OH•, H•, e-aq) that react quickly and non-selectively with contaminants in the water and wastewater and then decompotion them. In this paper, the history of using of electron beam and its applications in environmental pollution control in various scales, electron accelerators as electron beams production tools, reactors used for irradiation, Factors affecting the efficiency of this method, electron beams systems and advantages and disadvantages of electron beams is presented. Due to the strengths of this method than conventional methods and also lower costs and better performance, especially in the field of disinfection, sewage, sludge and color removal of wastewater industries, in the near future, is not far from the mind to be introduced as one of the key technologies in protecting the environment. Manuscript profile -
Open Access Article
124 - Applications Of Nanotechnology In Environmental Engineering
Reza Alizadeh Sodeh AbediniNanotechnology is science of employment materials device and systems in Nano scale that applications of Nano technology is reach in environmental engineering. For example water treatment by Nano filtration wastewater reatment clean energy produ MoreNanotechnology is science of employment materials device and systems in Nano scale that applications of Nano technology is reach in environmental engineering. For example water treatment by Nano filtration wastewater reatment clean energy production and nanotube for toxic gas adsorption. In this paper and research several application of this science for example fuel cell for energy production from clean sources, using from Nano filters for remove of hard water, water treatment for power plants, several application of carbon nanotube in the industry for example hydrogen storage in fuel cells for increase of yield them, toxic gas adsorption, using them instead ofgas sensors.. Manuscript profile -
Open Access Article
125 - Electricity production from living plants
Forouzan Vakili Lobat Taghavi Ebrahim AlaieLimited amounts of fossil fuels and energy sources in addition to their high pollution potential, make it necessary to replace it by renewable sources. The contribution of this kind of energy in the world energy supply system is increasing. In order to worldwide sustain MoreLimited amounts of fossil fuels and energy sources in addition to their high pollution potential, make it necessary to replace it by renewable sources. The contribution of this kind of energy in the world energy supply system is increasing. In order to worldwide sustainable development, International programs and policies including United Nations programs, has been assigned an essential role to renewable energy sources. So, new technologies inspired on nature, could be developed to produce electricity from sunlight by living plants action and photosynthesis. It’s based on cooperation and interaction between living plants, bacteria and a microbial fuel cell called Plant- MFC. In the Plant-MFC, living plants and bacteria were present to convert solar energy into green electricity. Microbial fuel cells could adsorb the energy produced from the reactions take place in rhizosphere by microbial actions and transformed it to the electricity. The main idea is that living plants produce rhizodeposites, mostly in the form of carbohydrates, and the bacteria convert these rhizodeposits into electrical energy via the fuel cell. This will not only provide the continuous use of solar energy in electricity generation, but also mitigate GHGs and other pollutants emission. In this article, the action of PMFCs in” green electricity” production from living plants, is explained. Manuscript profile -
Open Access Article
126 - Comparative study of cryptography and Telisman-opening of the beginning of feasts in Shahnameh and Haft Peykar
Leila Saei Nasser Naseri Tazeh Shahri Shahriar HassanzadehOne of the outstanding features of all fictional works with mental themes is their cryptic nature, so that this feature has a special effect and prominence in "Shahnameh" and "Haft Peykar", since elders and heroes to unravel complex codes and telismans with the help of MoreOne of the outstanding features of all fictional works with mental themes is their cryptic nature, so that this feature has a special effect and prominence in "Shahnameh" and "Haft Peykar", since elders and heroes to unravel complex codes and telismans with the help of Ahuras force and rationalists fought against the demonic forces, and sometimes resorted to cryptic acts to untie closed and difficult knots, and they rejoiced and feasted. The protagonists of the stories speak of tools such as astronomy and prediction of divine destiny, and consult with priests, clerics and dreamers to unravel the mysteries and secrets, and sometimes turn to astrology and knowledge of the misfortunes of Sepehri astronomers in order to achieve victory. In this article, scientific causation has been done in a descriptive-analytical and comparative way and the research results show that most of the celebrations have had roots in unlocking codes and telismans. Manuscript profile -
Open Access Article
127 - Reflection of Iranian celebrations in the poetry of Azerbaijani school poets
Leili Kamalvand Manouchehr Joukar Asad AbshiriniVarious celebrations have been held in Iran since ancient times; Among them are the celebrations that were held in each month, on the occasion of the symmetry of the name of the day with the name of the month, and each of them was accompanied by special customs. Many of MoreVarious celebrations have been held in Iran since ancient times; Among them are the celebrations that were held in each month, on the occasion of the symmetry of the name of the day with the name of the month, and each of them was accompanied by special customs. Many of these celebrations are forgotten today and are no longer held, but their traces and reflections can be found in the works of the past and classical poets; Among the poets of the Azerbaijani school. Accordingly, this study reflects the Iranian celebrations and related rituals in the poetry of the poets of the Azerbaijani school (with emphasis on Mujir al-Din Bilqani, Nezami, Khaghani and Falak Shervani). According to the findings of this study, among the ancient Iranian celebrations, only four ancient celebrations of Nowruz, Mehregan, Sedeh and Yalda are reflected in the poems of Azerbaijani poets and other ancient celebrations such as: Abangan, Bahmangan, Esfandgan, Tirgan and ... have not been reflected in the poems of these poets. Among these four celebrations, Nowruz celebration had the most reflection in the poems of Azerbaijani school poets and Century celebration had the least reflection among their poems. In total, Nowruz celebration has been repeated 71 times in the poems of these poets and only five times the celebration of the century has been mentioned. The reason for this is the great importance of Nowruz as the most important national holiday among Iranians. This research is a theoretical and library research. Manuscript profile -
Open Access Article
128 - Comparative Study of Excellence Path in Two mystical works: Resalat al – Teir & Jonathan Livingston Seagull
Vahid Mobarak Sahar YousefiThe comparative study attempts to appear the similarities and the related aspects of different tribes and nations; for instance it presents the philosophy of life and the general myth which mostly have figurative, mystic and symbolic language. Finding these similarities MoreThe comparative study attempts to appear the similarities and the related aspects of different tribes and nations; for instance it presents the philosophy of life and the general myth which mostly have figurative, mystic and symbolic language. Finding these similarities is an aid to human being to build the global society by more parallel and similar thoughts. Ibn – e Sina in his Resalat al Teir and Richard Bach in Jonathan Livingston Seagull have expressed the way to excellence with mysterious language. Both works explains the journey which describes a complete human. Resalat al Teir by Ibn – e Sina is the first philosophical work which affected many ones specially Attar's "Conference of the Birds". The present article evaluates Resalat al Teir and Jonathan Livingston Seagull by analyzing the data as well as studying the similarities and the differences. Manuscript profile -
Open Access Article
129 - Comparison of Langinus' treatise with Nezami Oroozi's book of "Chahar Maghaleh"
Ali Bazvand Arash AmrayiThis article examines the similarities between Nezami Oroozi's "Chahar Maghaleh" and Langinus' "Treatise". Langinus is one of the greatest critics known as Aristotle. In his literary and critical theory, he examines the characteristics of a literary work by proposing th MoreThis article examines the similarities between Nezami Oroozi's "Chahar Maghaleh" and Langinus' "Treatise". Langinus is one of the greatest critics known as Aristotle. In his literary and critical theory, he examines the characteristics of a literary work by proposing the category of "excellent model" and, in fact, shows the character of a literary masterpiece. Langinus believes that a literary work with its characteristics can be considered as an excellent example and model, and this excellent model is not limited to a literary genre. Nezami Oroozi Samarghandi, the author of "Chahar Maghaleh" in both the secretary's and poetic articles, believes that special circumstances can exalt a literary work. The present article explains Langinus' views and their conformity with the perspective of Nezami Oroozi. In the meantime, of course, it should be noted that the artistic and critical views of Iranian poets and writers are subject to certain rhetorical principles and foundations that may be different from the intellectual and rhetorical foundations of Western writers, but this study only seeks to find similarities that can be seen in these two works. Perhaps the analysis of these similarities can reveal the common sources in the two works and show signs of the presence and influence of Aristotle's views in both books. Manuscript profile -
Open Access Article
130 - A comparative study of Mehregan celebration with Turkish celebration of Birbiri Gorlak
Gholamreza Rahimi Shashdeh Sajjad FarahmandFolk literature is a part of people's culture that transmits the spiritual heritage, customs and traditions of one generation to another. According to the interest of the villagers in preserving their traditions and customs, in this article, we will examine the ancient MoreFolk literature is a part of people's culture that transmits the spiritual heritage, customs and traditions of one generation to another. According to the interest of the villagers in preserving their traditions and customs, in this article, we will examine the ancient tradition of Mehregan celebration that Birbiri Gorlak means seeing each other in the village of Qasr Yaghoub Safashahr in the Turkish language of Safashahri. We seek this folk tradition which was originally the same as the Mehregan celebration, but has evolved over time to keep alive the legacy of ancient Iran. Thus we take scientific and effective steps in the preservation of the traditions and rituals of ancient Iran, and to give the next generation the legacy left to us from the past as a trust, and to do our duty in this regard. Manuscript profile -
Open Access Article
131 - The concept of interpretation and the necessity of identifying the institution of modification in contracts from the perspective of general Quranic rules, Iranian and British law
hasan jahanshahlo vahid ghasemi ahdIn many long-term contracts, circumstances arise that make its implementation extremely difficult. Of course, it is very clear that the concept of difficulty or impunity is completely different from the concept of impossibility or impossibility of implementation. It may MoreIn many long-term contracts, circumstances arise that make its implementation extremely difficult. Of course, it is very clear that the concept of difficulty or impunity is completely different from the concept of impossibility or impossibility of implementation. It may not be possible to fulfill the contractual obligations, but it is very difficult to fulfill the obligation. Delays in contract enforcement are an important issue in most legal systems, such as the UK.If the occurrence of events and changes in the circumstances of the performance of the obligations of the contract cause excessive difficulty or unconventional loss for the obligor, the civil law in this case does not provide a clear solution. Due to the silence of the law, two solutions can be offered: First, we should not offer any solution based on principles such as contractual freedom and the principle of necessity, and we should ignore all the effects of the obligation to fulfill the obligation. Secondly, while acknowledging that the parties to the contract also foresaw the execution of the contract under normal circumstances, and considering that the execution of the obligation in such cases creates negative effects for the obligor, we should look for a suitable solution such as termination, termination and modification of the contract. Accordingly, while studying foreign law, based on the general Qur'anic rules such as the denial of hardship:other jurisprudential rules such as the denial of harm "no harm and no harm in Islam" to find a solution to We can modify contracts. Manuscript profile -
Open Access Article
132 - Status of Happiness in Quranic Life Style
Maryam Solgi Zahreh Sadat NabaviThe present research which is done with descriptive – analytical method, studies the concept of happiness relationship with Pure Life in Holy Quran. In narrative and interpretive references, Pure Life is mentioned as happiness repeatedly. But the philosophical &nd MoreThe present research which is done with descriptive – analytical method, studies the concept of happiness relationship with Pure Life in Holy Quran. In narrative and interpretive references, Pure Life is mentioned as happiness repeatedly. But the philosophical – religious concept of “happiness” is of ambiguity and various philosophical – religious schools offer different definitions. On the other hand, common aspect of all definitions of “happiness” with Pure Life is in their extremity. It means either Pure Life or all definitions of “happiness” emphasize the extremity of human lives as well as good living. Since based on ideology, human is a creature of both body and spirit and worldly life is a beginning of otherworldly life, thus real happiness contains any affair which meets the main aim of creating: approaching God. Manuscript profile -
Open Access Article
133 - Nationwide resistance against colonialism in the poetry of Lebanese poet Ibrahim al-Munzer
seyyed Aboalfazl Sajadi mohammad jorfi zahra kogheki nyyatThere is no doubt that colonialism forces resistance and protection that the defenders endeavor to achieve freedom; This poem has harmonies and ideas that inspire others to resist and protect against the colonialists.Ibrahim Munzer, a Lebanese poet, is one of the most p MoreThere is no doubt that colonialism forces resistance and protection that the defenders endeavor to achieve freedom; This poem has harmonies and ideas that inspire others to resist and protect against the colonialists.Ibrahim Munzer, a Lebanese poet, is one of the most prominent poets who stood up against the colonialists; he was a superpatriotic poet whose poetry retains the spirit of resistance.The outcomes of this study indicate that this poet is a resolute poet who has the spirit of patriotism and nationalism, irritation and rebellion against the colonialists and communication for brotherhood among the Arabs, and martyrdom for the cause of the motherland and the evolution of science and the conservancy of the Arabic language in There is his poetry.There is no doubt that colonialism forces resistance and protection that the defenders endeavor to achieve freedom; This poem has harmonies and ideas that inspire others to resist and protect against the colonialists.Ibrahim Munzer, a Lebanese poet, is one of the most prominent poets who stood up against the colonialists; he was a superpatriotic poet whose poetry retains the spirit of resistance.The outcomes of this study indicate that this poet is a resolute poet who has the spirit of patriotism and nationalism, irritation and rebellion against the colonialists and communication for brotherhood among the Arabs, and martyrdom for the cause of the motherland and the evolution of science and the conservancy of the Arabic language in There is his poetry. Manuscript profile -
Open Access Article
134 - Charity (Zakat) of His Excellency Ali (puh) in The Committed Literature
Hossein ChoobinCharity (Zakat) has different meanings; one is the literal meaning and the other is the religious one. His Excellency Ali (peace be upon him) paid his Charity (Zakat) while praying when he hears a poor man's words asking for help; he donated his signet. Different poets MoreCharity (Zakat) has different meanings; one is the literal meaning and the other is the religious one. His Excellency Ali (peace be upon him) paid his Charity (Zakat) while praying when he hears a poor man's words asking for help; he donated his signet. Different poets have poems about this event. Manuscript profile -
Open Access Article
135 - مطالعه مولکولی عوامل حدت جدایههای پاستورلا مولتوسیدای مربوط به طیور و بررسی کشندگی جدایههای حاد در جنین و نیمچه ماکیان
رحیم قدیمی پور مسعود قربانپور داریوش غریبی منصور میاحی احمد رضا جباری -
Open Access Article
136 - Analysis of the strategies of creating an entrepreneurial university in Abadeh city: using a mixed approach
somaye aghashiri مرضیه حیدریPurpose: This research was conducted with the aim of analyzing the strategies of creating an entrepreneurial university in line with the transformation and excellence document of Islamic Azad University. Method: The research method was a mixed method (qualitative and q MorePurpose: This research was conducted with the aim of analyzing the strategies of creating an entrepreneurial university in line with the transformation and excellence document of Islamic Azad University. Method: The research method was a mixed method (qualitative and quantitative) which was used in the qualitative part of Meta-analysis and in the quantitative part of the descriptive method of correlation. The statistical population of the qualitative section included numerous domestic and foreign studies, which included 20 studies in the form of targeted sampling after screening the above studies. Also, in the quantitative part, the statistical population includes all active professors and experts in the field of entrepreneurship from the Islamic Azad University of Shiraz branch and its subsidiary units in the province in the number of 111 people who were selected through the entire population. Validity was done in a qualitative way using the triangulation method and in a quantitative way through a formal content method (with the approval of several professors of the university), which were approved after the desired reforms. In order to analyze the findings of this study in the qualitative part of document mining, due to the use of a Meta-analysis approach in the form of extracting concepts and conceptual codes and converting them into the dimensions of the desired model. Findings: The results showed that creative-technological factors, organizational factors, infrastructural-social factors and financial-economic factors were recognized as strategies for creating an entrepreneurial university in line with the transformation and excellence document of Islamic Azad University. Conclusion: Therefore, in order to develop the path of entrepreneurship in entrepreneurial university and in accordance with the transformation and excellence document of Azad University. Manuscript profile -
Open Access Article
137 - identify the components and indicators of organizational excellence management in order to evaluate the performance of public schools
hamidreza Ashrafi Batool Faghiharam Abbas Khorshidi Saeed Moradi Leila SharifianPurpose: The main purpose of this article was to identify the components and indicators of organizational excellence management in order to evaluate the performance of public schools of the second year of high school in Tehran. Method: The research method is mixed (qua MorePurpose: The main purpose of this article was to identify the components and indicators of organizational excellence management in order to evaluate the performance of public schools of the second year of high school in Tehran. Method: The research method is mixed (qualitative-quantitative). In addition to document study, the Delphi technique has been used to identify the components and indicators of organizational excellence management in order to evaluate the performance of public schools. The statistical population in this research was all the experts in the field of professors, elites and experts of the Educational Research and Planning Organization, and 15 interviews were conducted until theoretical saturation. Semi-structured interviews with experts were conducted in the form of a questionnaire with 79 indicators and 19 components and one open-ended question. Findings: According to the semi-structured interviews and finally using the Delphi technique, 19 components and 76 indicators were confirmed. The results of structural equations showed that all indicators confirm their components and the components confirm the main variable. The convergent and divergent validity of the model was also confirmed. Conclusion: Establishment of organizational excellence management system and performance evaluation based on it can be important solutions in improving the quality of public schools. Manuscript profile -
Open Access Article
138 - Jurisprudential investigation of interplay of cancelling of the contract and pre-emption on each other
akbar zakerian سید عبدالمطلب احمدزاده بزارABSTRACT: Dre-emption is a right that lawgiver under a condition has recognized it of an interests for one of the jointly-owned proprietary ,which the source of it ; is a contract of sale that is concluded between the one of the partners and third parties, since this c MoreABSTRACT: Dre-emption is a right that lawgiver under a condition has recognized it of an interests for one of the jointly-owned proprietary ,which the source of it ; is a contract of sale that is concluded between the one of the partners and third parties, since this contract may cancelled of the contract by the affected of mutual agreement , and through sales get returned to the proprietary of the seller and the price go back to the proprietary of the purchaser, there will be two situation, the first situation is a where cancelling of the contract gets before the actions of the per-emption by middleman and in the second situation cancelling of the contract gets after the pre-emption . Most jurisprudents believe that because creation of pre-emption arises as soon as the contract of sale and it as an earned right will be to the middleman ; the next cancelling of the contract can not affect it and causing it to be destroyed rather, it is pre-emption that if it be done after the cancelling of contract causes the resolve of the cancelling of contract .Against this statement , some of jurists also believe that sinse it get returned to the proprietary of the seller object of sale the cancelling of contract ; so does not remain local for the pre-emption because it's the parts of pre-emption that parts of selling owned by the purchaser. KEY WORDS: Pre-emption, Cancelling Of The Contract, Object Of Sale , Purchaser, Middleman. Manuscript profile -
Open Access Article
139 - Jurisprudence study of the relation and its legal effects in human simulation
mostafa ameri siahooyi alireza asgari mohammad mahdi ahmadi ahmad moradkhaniSimulation or cloning is one of the nascent methods of the medical world in the treatment of infertility, which, unlike normal reproduction, is a living creature without fertilization and a combination of a physical cell and a sexual cell. The right to assign the child MoreSimulation or cloning is one of the nascent methods of the medical world in the treatment of infertility, which, unlike normal reproduction, is a living creature without fertilization and a combination of a physical cell and a sexual cell. The right to assign the child to his or her parent is one of the most fundamental human rights. This article attempts to answer the questions and challenges in the jurisprudential review of the status of parental affairs in a child. Here, reproduction of the dual origin (parent) is compared to the genetic characteristics of the child and reproduction simulations of the parent (father or mother), and, moreover, the simulation license in the context of the conjugation relationship or the outside It is also being discussed. Every available ideas gives different results that various aspects of it are considered in the judgments of the Imams, and, finally, it is stated that, firstly, there is a relation in simulation. Secondly, the parent and the owner of the cell Cloned as the child's parent, that is, the owner of the cell and the child derived from the owner of the cell, are also twins. Also, the works of Nasab will be include the respect of marriage, custody of the child, Qahiri province, the obligation to spend, and inheritance. Manuscript profile -
Open Access Article
140 - Civil Responsibility of Abolition and Abolition Condition in Contracts
zahra memaryan Sayyed abolfazl hoseini sirat mehdi mirdadashimCivil responsibility has two common meanings: conventional responsibility and unconventional responsibility. Although conventional responsibility is caused as the result of private contract's violation, unconventional responsibility is not the same. It is the result of MoreCivil responsibility has two common meanings: conventional responsibility and unconventional responsibility. Although conventional responsibility is caused as the result of private contract's violation, unconventional responsibility is not the same. It is the result of damage caused by a person to the other. So, the person is responsible to compensate the damage. Considering condition in contract means its achievement . Therefore, the condition will be null and void if it is impossible. One of the contract's disbandment's reasons is revoker condition. According to this condition, parties agree to cancel the contract if an event, action or inaction happen. In this condition, the contract is cancelled by conditioned issue. This leads to volitional cancellation and the result is appeared compulsorily. The duration of revoker condition should be cleared. Additionally, it is impossible to write it in all contracts. When the revoker condition is applied, parties are not allowed to do something against the other's right. Manuscript profile -
Open Access Article
141 - The Basics of Epistemology of theist Existentialism And Allame Tabatabai
ghazalleh dolati mahmod namazi hadi vasei mohamad hosein irandoostExistentialism is one of the most important contemporary currents in Western philosophy, and it is commonly known as the God-centered and atheistic spectrum, and the most important subject being discussed is human existence and emphasis on its authority. On the other ha MoreExistentialism is one of the most important contemporary currents in Western philosophy, and it is commonly known as the God-centered and atheistic spectrum, and the most important subject being discussed is human existence and emphasis on its authority. On the other hand, in the field of Islamic philosophy, Allameh Tabatabai, in contemporary times, has played a very important role in explaining and completing Islamic philosophy, especially Sadra'i philosophy. Since the foundations of epistemology are one of the most important roots in the formation of any intellectual process, the present article attempts to establish the foundations of the epistemology of theisticist existentialism (based on the views of Kierkegaard, Jaspers and Marcel) in comparison with the foundations of knowledge Allameh Tabatabai's Study. This article states that the foundations of epistemology of existentialism are rooted in humanism, and the problem of knowing is a completely personal event, with mental experience and phenomenological methods, while the epistemology of the Allameh is rooted in the rational and revelatory teachings of Islam It is based on a rational and rational method, and knowledge is truth in accordance with the actual and independent of the perception and perception of ma Manuscript profile -
Open Access Article
142 - Evolution of bovine embryos cleavage in co-cultuer M.S.Cs deried from adipose tissues rat
Mehdi Ahmadifar علی محمدعینی Reihane Nateghi Nazila وحیدی ایریسفلیObjectiveMesenchyme Stem cells (MSCs) are one of the widely used sources in tissue engineering and efficacy of cultural environment. In this survey, rat stem cells are used as coculture. Owing to main obstacle of embryo culture in the lab medium, the survival of embryo MoreObjectiveMesenchyme Stem cells (MSCs) are one of the widely used sources in tissue engineering and efficacy of cultural environment. In this survey, rat stem cells are used as coculture. Owing to main obstacle of embryo culture in the lab medium, the survival of embryo in lab is low in comparison with that of normal conditions. The purpose of this research is the survey of fertilization and culture of bovine embryos in mesenchymal stem cells derived from adipose tissue (ADMCs).ApproachIsolated ADMCs were cultured on 4-well dishes. Three days after cell culture, the bovine immature oocytes were transferred on this mono layer system and the in vitro matured oocytes were fertilized by sperms in another MSCs free environment subsequently. Then in vitro fertilized embryos were co-cultured with the same mono layer of ADMCs for seven days. During oocyte and embryo co-culture, the rates of maturation and cleavage were assessed.AchievementsThis study reveals that co-culture of embryos with mesenchymal stem cells could increase the survival and cleavage of embryos significantly (P<0.05). The maturation rate of bovine co-cultured oocytes (%82) in comparison with that of control group (%78) has increased significantly. Also, the rate of blastocyst formation in co-cultured embryos (%33) was analytically comparable with that of control group (%26).ConclusionWhat bolsters substantially the quality and development of embryo is coculture systems. Manuscript profile -
Open Access Article
143 - Identification and propagation of human spermatogonial stem cells
Zeynab Piravar Shokouh CheginiSpermatogonial stem cells (SSCs) are a self-renewing population of adult stem cells. These cells could restors reproduction throughout the life of the male by sperm production. In non-primate mammals, spermatogonial stem cells named A-single (As), and the A-paired (Apr) MoreSpermatogonial stem cells (SSCs) are a self-renewing population of adult stem cells. These cells could restors reproduction throughout the life of the male by sperm production. In non-primate mammals, spermatogonial stem cells named A-single (As), and the A-paired (Apr) and A-aligned (Aal) are the progenitor spermatogonial population. In human, very little findings is available about SSCs. there are two different types of A spermatogonia, the Adark and Apale spermatogonia. The Adark spermatogonia were referred to as the reserve stem cells, whereas the Apale were considered the renewing stem cells. Regulation of the SSC population includes establishment and maintenance of a niche microenvironment in the seminiferous tubules of the testis. Signaling from somatic cells within the niche determines the fate of SSCs by either supporting self-renewal or initiating differentiation to spermatozoa. Although numerous expression markers have been helpful in isolating and enriching spermatogonial stem cells, no specific marker for this cell type has yet been identified. Culture of testicular cells on various feeder cells has made it possible to culture and expansion of spermatogonial stem cells for a long period of time and hormones and growth factors are investigated for their role in the process of proliferation of spermatogonial stem cells. Manuscript profile -
Open Access Article
144 - Prevalence of bacterial contamination of cord blood stem cells units stored in cord blood bank of the Academic Center for Education, Culture and Research (ACECR), Qom between 2012 to 2015
mohsen sheykhhasan maryam faraji mahdieh ghiasiBackground and Objectives: Umbilical cord blood has been used as a major source of hematopoietic stem cells to treat a variety of blood diseases. There is bacterial contamination risk during sampling from the umbilical cord and the processing related to it. The aim of t MoreBackground and Objectives: Umbilical cord blood has been used as a major source of hematopoietic stem cells to treat a variety of blood diseases. There is bacterial contamination risk during sampling from the umbilical cord and the processing related to it. The aim of this study was to determine the origin and type of bacterial contamination contaminated samples available in cord blood bank of the Academic Center for Education, Culture and Research (ACECR), Qom.Materials and Methods: In this study, 370 units of cord blood were collected and examined for bacterial contamination. In order to identify the source of pollution, preparation and determination culture strains was carry out in both blood sampling and finally to storage levels. Results were analyzed by SPSS software. Results: A total of 370 cord blood units, 5 units had bacterial contamination. The number of units in phase 2 was positive for bacterial cultures and 3 blood samples were also positive after processing.Conclusions: In this study, the rates of bacterial infections were reported as 5% in both the blood sampling and the processing, and the majority of isolated bacteria were of Staphylococcus aureus and Staphylococcus epidermidis, however, due to the high value and importance of blood stem cell cord and the risk of septic transplantation, develop training programs in order to obtain a sterile preparation is necessary. Manuscript profile -
Open Access Article
145 - Immobilization of laccase in nafion and carbon nanotubes biocathode of Biofuel cells and Biosensors
maasome ahmadiNowadays demands for clean power source enhanced. Bio-fuel cell (BFC) can convert chemical energy to electrical energy. The enzyme-based biofuel cell (BFC) is a special fuel cell using enzyme as catalyst and can directly convert chemical energy to electrical energy. Bio MoreNowadays demands for clean power source enhanced. Bio-fuel cell (BFC) can convert chemical energy to electrical energy. The enzyme-based biofuel cell (BFC) is a special fuel cell using enzyme as catalyst and can directly convert chemical energy to electrical energy. Bio-fuel cells are energy conversion devices based on bio-electrocatalysis leveraging on enzymes or microorganisms. Enzymatic fuel cells are promising low cost, compact and flexible energy resources. The basis of enzymatic fuel cells is transfer of electron from enzyme to the electrode surface and vice versa.. The DET of laccase enzyme has been studied using Multi-walled carbon nanotubes (MWCNTs)/Nafion polymer. Laccase was entrapped by nafion polymer . As Nafion is a proton exchange polymer but not an electron conductive, the MWCNTs were also used to facilitate electron transfer of laccase. Cyclic voltammetric results showed a well-defined redox peaks at 170 µA in a solution containing 10 µM o-dianisidine as a substrate for MWCNTs/Nafion composite. The cyclic voltammetric results showed that laccase immobilization on MWCNTs/Nafion is efficient. Therefore, this method can be used to fabricate biocathode of biofuels cellor laccase based biosensors. Manuscript profile -
Open Access Article
146 - Review on Laboratory tests for Diagnosis of Hepatitis C Virus Infection
Abbas Morovvati somayeh dehghani sanij Ashkan Dirbaziyan homa Azadegan shima Aghaei hasan vahidi emamiAbstract Hepatitis C virus (HCV) infection is associated with chronic hepatitis, cirrhosis, and hepatocellular carcinoma. This review summarizes the pathogenesis and significance of serological and molecular-based assays and new methods in the diagnosis and management o MoreAbstract Hepatitis C virus (HCV) infection is associated with chronic hepatitis, cirrhosis, and hepatocellular carcinoma. This review summarizes the pathogenesis and significance of serological and molecular-based assays and new methods in the diagnosis and management of HCV infection after reading this article, readers should be able to describe laboratory tests used in the diagnosis and management of HCV infection. They should also be able to describe the general principles for selecting the most appropriate laboratory test for diagnosis, therapeutic decision making, and assessment of virologic response to therapy. New methods for diagnosis of HCV virus infection could help for HCV detection and virus Genotypes in patient. Molecular methods are very sensitive and specific for RNA diagnosis and uses of this test for HCV genotypes Because HCV genotypes different response to druges.HCV genotypes detection could help for follow up treatment by interferon of patient. Keywords: hepatitis C virus, hepatitis, hepatocellular carcinoma, molecular diagnostics Manuscript profile -
Open Access Article
147 - Studying the effect of co-culture system of Mesenchymal Stem Cells on development of follicles in mice ovary in vitro
Ali Mohammadeini Ahmad Ali Mohammadpour Abbas ParhamObjective: Many researchers are trying to clarify necessary hormonal factors for structural distinguishability and functional activities of ovarian tissue by using cell culture and tissue culture techniques. Hence, in this study, we examined ovarian tissue culture on me MoreObjective: Many researchers are trying to clarify necessary hormonal factors for structural distinguishability and functional activities of ovarian tissue by using cell culture and tissue culture techniques. Hence, in this study, we examined ovarian tissue culture on mesenchymal stem cells isolated from cultured adipose tissue.Materials and methods: In this study, mesenchymal stem cells became isolated from adipose tissue of the mouse. After five days and monolayer formation of Mesenchymal stem cells, obtained ovarian was placed on the cultured Mesenchymal stem cells’ monolayer for 7 days.Results: The results of this study show that numbers of mature follicles for treat group compared to the control group were 61/1±2/2 and 38/1±1/9, respectively which had a significant increase compared to control group (P<0/05). This shows the efficiency of tissue culture in co-culture with Mesenchymal stem cells. The real-time PCR studies also confirmed the decrease in the BAX genes in treatment Groups to compare the control group (P<0/05). According to the results yielded regarding the number and quality of obtained follicles, it seems that this method is efficient and of high importance in producing mature follicles, and subsequently high quality oocytes and embryo. Manuscript profile -
Open Access Article
148 - Identification of volatile compounds and investigation of antioxidant, antimicrobial and anticancer effects of Tribulus longipetalus Viv
Aliakbar ImaniObjectives: The objective of the present study was to identify volatile compounds and investigate the antioxidant, antimicrobial and anticancer effects of Tribulus longipetalus Viv.Materials and methods: In this research, the Tribulus longipetalus Viv, which is an annua MoreObjectives: The objective of the present study was to identify volatile compounds and investigate the antioxidant, antimicrobial and anticancer effects of Tribulus longipetalus Viv.Materials and methods: In this research, the Tribulus longipetalus Viv, which is an annual herbaceous plant, has many branches, lies on the ground, and has stems with soft hairs. The geographical spread of this plant is in the long sand dunes of Aran and Bidgol deserts. Biological properties, including free radical scavenging activity, total amount of phenolic compounds, antimicrobial properties and cytotoxic properties were investigated. Since the whole plant extract showed a high level of inhibition in the saltwater shrimp cell toxicity test (nearly 70 μg/liter), in order to obtain the effective components, solvent extraction using a decanter funnel was on the agenda. The three obtained components of hexane, ethyl acetate and water were analyzed separately. Also, by using a polystyrene divinylbenzene chromatography column, the effective component with higher inhibition ability was isolated. Among the effective components, except ethyl acetate, it had a relatively high inhibitory power, which was identified with the help of Hplc device.Findings: Comparing the antimicrobial power of Tribulus longipetalusViv with antibiotics, showed that this plant has good antimicrobial properties. Also, considering that LC50 was determined as 70 μg/ml. This value indicates the good cytotoxic power of Tribulus longipetalus Viv. Manuscript profile -
Open Access Article
149 - Anticancer effect of digitalis nervosa hydroalcoholic extract on cervical cancer cell line (Hela)
Nazila Ahmadzadeh Nstran Asghari Moghadam Zahra KeshtmandObjective: Today, with the high prevalence of cancer, the need for drugs with fewer side effects and better therapeutic effects has been noticed by researchers, so that a large percentage of anti-cancer compounds are prepared from natural sources. The purpose of this st MoreObjective: Today, with the high prevalence of cancer, the need for drugs with fewer side effects and better therapeutic effects has been noticed by researchers, so that a large percentage of anti-cancer compounds are prepared from natural sources. The purpose of this study is to investigate the anticancer effects of digitalis nervosa hydroalcoholic extract on uterine cancer cell line (Hela).Materials and methods: In this experimental study, the hydroalcoholic extract of the marigold plant was prepared. Then, Hela cancer cell line was treated with different concentrations of the extract (3.125, 6.25, 12.5, 25, 50 and 100 μg/ml) for 24 hours and the cytotoxicity of the extract was evaluated by MTT method. Finally, the expression level of Bax, Bcl2, P53 and CDH1 genes at 50% lethality concentration was investigated by Time-Real PCR method. Data were analyzed using SPSS software and one-way variance test.Findings: According to the results of the MTT test, the hydroalcoholic extract of foxglove has a dose-dependent cytotoxic effect against the cell line, and the concentration of 50% lethality was determined to be 24.67 micrograms per milliliter. Also, at the concentration (24.67 μg/ml), the expression of apoptotic genes Bax, CDH1 and P53 increased and the expression of Bcl2 gene decreased compared to the reference gene.Conclusion: Thimble flower plant extract has cytotoxicity and apoptosis induction effect on Hela cancer cells. Manuscript profile -
Open Access Article
150 - Reading the figurative language of Mathnavi Mowlavi's "Neynameh" based on Celena Kusch's "close reading" method
Abdolhamid Amani Abbas Mohammadian Mahyar Alavi Moghaddam Ahmad KhajehimThe aim of this study is to read the figurative language of Mathnavi Mowlavi's "Neynameh" based­ on Celena Kusch's "close reading" method. An approach that in addition to interpreting linguistic details and their interrelationships also requires the analysis of othe MoreThe aim of this study is to read the figurative language of Mathnavi Mowlavi's "Neynameh" based­ on Celena Kusch's "close reading" method. An approach that in addition to interpreting linguistic details and their interrelationships also requires the analysis of other variables such as context, intertextuality, narrative and text genre. This article tries to answer these questions in a descriptive-analytical way. What is the poet's strategy in using figurative language in Mathnavi's "Neynameh"? What is the function of each figurative in achieving the goals of this text and its overall coherence? The results prove that the figures used in Neynameh fall into two general groups during a coherent process: 1) related to "Beshnow"; 2) related to "Ney"; the first group, with increasing music, urges the audience to "listen"; demonstrates the principle of unity in plurality; and the second group, manifestations of self- empty, the struggle of the soul for freedom from the cage, the virtual of our world; The being incomprehensible of love and so on. Manuscript profile -
Open Access Article
151 - ‘‘Elegance observes but Elegance’’ Sheikh Mahmoud Shabestari’s Vision on the most Elegant System
Majid Noorikhkgkhkg Manuscript profile -
Open Access Article
152 - The Concept of “the Transcendental” and Lack of “Relation” in Plotinus Philosophy
tahere Mesgar Heraviksj -
Open Access Article
153 - The Use of Nanoemulsion-based Strategies to Improve Corrosion inhibition Efficiency of Herbal Extract Inhibitors
Meysam Ahmadi-Zeidabadi Razieh Razavi Mahnaz Amiri Seyed Hamzeh Hosseini Maryam Payandeh -
Open Access Article
154 - Investigations on Optoelectronic Properties of New low Gap Compounds Based on Pyrrole as Solar Cells Materials
O. Ninis S.M. Bouzzine H. Toufik F. Lamchouri M. Abarkan M. Hamidi M. Bouachrine -
Open Access Article
155 - Effect of Solvents on the Synthesis of SrAl2O4 Nanoparticles by Reverse Micelle Process
Azita Moheb Saeid Abedini Khorramie Shahram Moradi Dehagi -
Open Access Article
156 - Investigations of New Low Gap Conjugated Compounds Based on Thiophene-Phenylene as Solar Cells Materials
Mansour Amine Amina Amine Mohammed Hamidi Si Mohammed Bouzzine Mohammed Bouachrine -
Open Access Article
157 - Aging Study of Transformer Oil-Impregnated Repulped and Standard Cellulose by Measuring of 2-furfural Content of the Oil
Ali Ramazani Rana Rahmati Solmaz Bigdeli Sohrab Rahmani Mehrdad Hamidi -
Open Access Article
158 - Investigation of the Drug Delivery Potential of a Transdermal Patch Based on Buprenorphine Templated Molecular Imprinted Polymer
Nasrin Behnia Parviz Aberoomand Azar Maryam Shekarchi Mohammad Saber Tehrani Noushin Adib -
Open Access Article
159 - One-pot Synthesis of Pyrano[2,3-d]Pyrimidines using Nanocellulose-SbCl5 as a Highly Efficient and Bio-based Catalyst
Marziyeh Rouhi Bahareh Sadeghi Mohammad Hosain Moslemin Saleheh Zavar -
Open Access Article
160 - Binuclear Complex of Zinc and Copper with Unsymmetrical Macrocyclic Ligand as Sensitizer in Nanocrystaline TiO2 Solar Cells
Malihe Khalili Mohammad Abedi Davood Sadeghi Fateh Kobra Razmi -
Open Access Article
161 - Synthesis of Sulfonated Polystyrene/acrylate–ionic Liquid (Si-SPS/A–IL) Hybrid Membranes for Methanol Fuel Cells
Mohammad Galehassadi Alireza Khani -
Open Access Article
162 - Antibacterial Activity and Conductivity Properties of Nanocomposites based on Cellulose Acetate Nanofibers and Copper Nanoparticles
Mohsen Sargordan -Arani Elham Alsadat Hoseini Behrooz Mirza -
Open Access Article
163 - Quantum Chemical Investigation of the Photovoltaic Properties of Conjugated Molecules Based Oligothiophene and Carbazole
N. Belghiti M.N. Bennani Si Mohamed Bouzzine Mohamed Hamidi Mohamed Bouachrine -
Open Access Article
164 - Antibacterial and Cytotoxicity Effects of TiO2-Grafted Cellulose Nanocomposite
Zari Fallah Hossein Nasr Isfahani Mahmood Tajbakhsh Mojtaba Mohseni Hamed Tashakkorian Abdoliman Amouei Ebrahim Zabihi Zeinab Abedian -
Open Access Article
165 - Aging Study of Oil Impregnated Repulped and Standard Cellulose through Measuring Viscometric Degree of Polymerization
Sohrab Rahmani Rana Rahmati Ali Ramazani -
Open Access Article
166 - Handoff Optimization for Joint Base Station Association and Power Control with Proportional Fairness in NOMA Small-Cell Networks
Sina Pirnia Hamidreza Bakhshi Mohamad Dosaranian-Moghadam Ramin KhosraviThe handoff rate and load balancing are two important issues that have a great impact on the spectrum and energy efficiency in the small cell networks. This paper investigates the handoff optimization in small cell networks with power-domain non-orthogonal multiple acce MoreThe handoff rate and load balancing are two important issues that have a great impact on the spectrum and energy efficiency in the small cell networks. This paper investigates the handoff optimization in small cell networks with power-domain non-orthogonal multiple access that uses successive interference cancellation, considering the fairness among base stations. We study the joint base station association and power control problem by considering the motion of mobile users and load balancing in the small cell networks. Under the maximum allowable transmit power and minimum average-rate constraints, two optimization problems are formulated using the number of associated mobile users, the number of handoffs, and the transmit power of all MUs. The total power consumption minimization and the system-wide and handoff utility maximization problems are combined into a single-stage optimization problem through the weighted sum method. We solve the formulated problem using a game theory-based algorithm and primal decomposition theory. The simulation results show that our proposed algorithm can significantly reduce the frequent handoffs and bring a fair power-controlled BS association in small cell networks. Manuscript profile -
Open Access Article
167 - Millimeter-Wave Underlay D2D Communications: Channel Assignment, Transmission mode Selection and Power Control for Full-CSI and Limited-CSI Scenarios
Nima ReisiIn this paper, we study relay-assisted underlay D2D communication operating at millimeter-wave (mmWave) band in which half-duplex/full-duplex relays may assist D2D users to improve transmission quality. Our aim is to jointly select D2D transmission mode, assign cellular MoreIn this paper, we study relay-assisted underlay D2D communication operating at millimeter-wave (mmWave) band in which half-duplex/full-duplex relays may assist D2D users to improve transmission quality. Our aim is to jointly select D2D transmission mode, assign cellular resource blocks to D2D users and control the powers of users in order to maximize the aggregate data rate of the D2D users and cellular network. We focus on the main features of mmWave communication including larger bandwidth, directive antenna arrays at BS and users, and more severe path loss and shadowing. As the optimization problem is mixed-integer-non-linear programming, two heuristic algorithms are proposed, assuming full Channel Side Information (CSI) and limited CSI at Base Station, respectively. Simulation results show the superiority of utilizing FD relays over HD relays and direct transmission, especially for non-line-of-sight links, which is the dominant propagation mechanism in mmWave band. The limited CSI algorithm has considerably lower complexity. Moreover, when the number of resource blocks far exceeds the number of D2D users, the gap between full CSI and limited CSI algorithms vanishes. Manuscript profile -
Open Access Article
168 - Resource Management in Hybrid Millimeter-Wave and Microwave Ultra-Dense Networks using TDD Duplexing
Zahra Mahjoobi Nima ReisiMillimeter wave (mW) communication is one of the key enabling technologies for meeting the vast data demand growth and bandwith scarcity. The mmWave band offers higher bandwidth compare with those presently used in commercial wireless systems, which resuls in higher ach MoreMillimeter wave (mW) communication is one of the key enabling technologies for meeting the vast data demand growth and bandwith scarcity. The mmWave band offers higher bandwidth compare with those presently used in commercial wireless systems, which resuls in higher achievable capacity. To improve the user experience in the 5G communication, it is proposed to utilize the composition of microwave (μW) and millimeter wave networks. On the other hand, an ultra-dense network (UDN) has been envisioned as a promising network paradigm for spectrum efficiency enhancement. In this paper, the cellular network using TDD duplexing, consists of both mW and μW base stations. BSs and users are distributed in both indoor and outdoor environments with Poisson point distribution. Our aim is to calculate the spectral efficiency for both mW and μW sysyems, based on the base stations and users distribution. Moreover, the effect of BS density on spectral efficiency is evaluated. Finally, the problem of maximizing the downlink rate is formulated and solved as a linear optimization problem so that the minimum uplink rate is guaranted. The simulation results show that by servicing both mW and μW simultaneously on uplink and downlink, high spectral efficiency can be achieved and with the help of optimal resources allocation, the network’s perfomance is improved about 3dB. Manuscript profile -
Open Access Article
169 - Presentation of hardware method of error reduction in electronic devices of quantum nanosatellites
Mojdeh Mahdavi Mohammad Amin Amiri Vahid sadatpourToday, space technology is recognized as one of the competitive fields among countries and the various achievements of space technology are an accurate basis for comparing countries in terms of industrial development. In the near future, nanosatellites will become the m MoreToday, space technology is recognized as one of the competitive fields among countries and the various achievements of space technology are an accurate basis for comparing countries in terms of industrial development. In the near future, nanosatellites will become the main trend in the development of regional terrestrial monitoring and positioning. The turnover of a satellite is millions of dollars, so a significant part of each country's investment is in the aerospace sector, and in the event of failure, a large cost will be imposed on the manufacturer. For this reason, before launching a satellite, considerations are made so that the satellites can perform the assigned operations without the slightest error. Until now, the use of microelectronic circuits has been common in space applications due to their advantages, including availability and reconfigurability, but these components are vulnerable to the radiation environment. On the other hand, due to the rapid changes in electronics to nanotechnology and the advantages of nanoelectronic circuits, in the not too distant future, nanoelectronics components will be a viable alternative in space applications. As the size of the components decreases, the orbits become more sensitive and the quantum circuits become more vulnerable to radiation from space. In this paper, we present the method of increasing the fault tolerance and their simulation in the binary wire of nanosatellites in quantum cellular automation technology. Manuscript profile -
Open Access Article
170 - Generalize and improve the traditional true proportional navigation guidance law
Roholah Manei Mahdi SiahiUndoubtedly, studying the guidance of tactical nesting missiles without considering proportional navigation is a very difficult task. And researchers have always tried to develop and eliminate the weaknesses of these guidance laws and their various strategies, to preven MoreUndoubtedly, studying the guidance of tactical nesting missiles without considering proportional navigation is a very difficult task. And researchers have always tried to develop and eliminate the weaknesses of these guidance laws and their various strategies, to prevent disturbances in the missile control system. This article also discusses the various strategies for improving the traditional true proportional navigation law and its equations. And then by drawing graphs and comparing their equations, the superior strategy in different modes is introduced. Manuscript profile -
Open Access Article
171 - Synthesis of aerosol spray pyrolysis based on CZTS nanostructures for photovoltaic applications
mojtaba jamiatiAs the detrimental effects of the extraction, treatment and combustion of natural resources for energy production are clearly understood, the need for renewable energy becomes more favorable with economic competition. Solar power generation is a technically viable metho MoreAs the detrimental effects of the extraction, treatment and combustion of natural resources for energy production are clearly understood, the need for renewable energy becomes more favorable with economic competition. Solar power generation is a technically viable method, although the main drawback is the cost. Traditional silicon-based single-crystal photovoltaics are too expensive to compete with non-renewable energy, while alternative materials such as cadmium telluride and copper-indium-gallium-selenide contain expensive and unstable elements, while cadmium is a carcinogen. Za is known. Copper-zinc-tin sulfide (CZTS) is another alternative, although the technology is not yet advanced enough to enter the market. The present work is a study on the synthesis of CZTS nanostructures using aerosol spray pyrolysis based on CZTS nanostructures for photovoltaic applications in an inexpensive, environmentally friendly and industrially extensible manner. We dissolve a precursor solution with air-soluble copper, zinc, and tin compounds and pass the droplets through the furnace, where the precursors dissolve to form CZTS structures thermally. Using this method, we can produce thin films - by placing a substrate inside the furnace - and nanoparticles. Manuscript profile -
Open Access Article
172 - Green Synthesis and Characterization of Fe3O4 Nanoparticles Using Aqueous Extract of Spent Tea Waste and its Application in the Preparation of Fe3O4/Cellulose Nanocomposite
A. Azizi K. Khosravi -
Open Access Article
173 - Synthesis, Characterization and Antibacterial Activity of CNT-TiO2-Ag Ternary Hybrid
M. Fazlollahpour M. Akbarzadeh-Pasha S. Ahmadi-Asbchin -
Open Access Article
174 - Effect of Non-Newtonian Models on Blood Flow in Artery with Different Consecutive Stenosis
Mehdi Jahangiri Ahmad Haghani Reza Ghaderi Seyyed Mohammad Hosseini Harat -
Open Access Article
175 - Numerical simulation of multilayer cellular scaffolds with 3D and 1D elements
Hamid Reza khanaki Sadegh Rahmati Mohammad Nikkhoo Mohammad Haghpanahi Javad Akbari -
Open Access Article
176 - Investigation of the AFM Indenter’s Geometry Effect On Micro/Nano Biological Cells’ Indentation
Yousef Habibi Sooha Moharam Habibnejad Zahra Rastegar -
Open Access Article
177 - Label-Free Perfect Separation of Michigan Cancer Foundation-7 Cells from White Blood Cells using Both Wall-Induced Lift and Dielectrophoresis Forces
Alireza Alaghemand Ali Fattah -
Open Access Article
178 - Mechanical Properties of Materially and Geometrically Gradient Cellular Structures Manufactured with SLS 3D Printer Applicable as a Bone Implant
Ali Salehi Alireza Daneshmehr Kiyarash Aminfar -
Open Access Article
179 - Modelling and Control of Mutation Dynamics of the Cancer Cells Employing Chemotherapy
Hami Tourajizadeh zahra zarandi zakie farbodi ehsan sadeghi -
Open Access Article
180 - Simulation of Friction Stir Extrusion using Smoothed Particle Hydrodynamics (SPH)
Mostafa Akbari Mansour Hakimollahi parviz Asadi Hossein Rahimi Asiabaraki -
Open Access Article
181 - Molecular docking, anti-inflammatory, antimicrobial and antioxidant evaluation of Pterospermum rubiginosum B. Heyne
Rajamohanan Anish Fathima Rumaisa Thankamani Aswathy Velappan Nair Kalpana Arun Rauf -
Open Access Article
182 - Antioxidant activity of phytol dominated stem bark and leaf essential oils of Celtis zenkeri Engl.
Ejike Okpala Patricia Onocha Muhammad Ali -
Open Access Article
183 - Chemical constituents from the leaves of Fraxinus excelsior L., Senna sulfurea (Collad.) H. S. Irwin et Barneby and Prosopis cineraria (L.) Druce
Shahnaz Sultana Mohammed Ali Mohammad Jameel Piyush Sharma -
Open Access Article
184 - Role of Cognitive Flexibility and Emotional Regulation Problems in Prediction of Celebrity WorshipamongUniversity Students
Reza Shabahang Mohammad Ali Besharat mansooreh nikoogoftar Farzin Bagheri SheykhangafsheWorshiping celebrities is a complex and multidimensional issue that cognitive flexibility and emotional regulation are among the most important factors that can be effective in celebrity worship. This study aims to investigate the role of cognitive flexibility and emoti MoreWorshiping celebrities is a complex and multidimensional issue that cognitive flexibility and emotional regulation are among the most important factors that can be effective in celebrity worship. This study aims to investigate the role of cognitive flexibility and emotional regulation problems in predictionof celebrity worshipamonguniversity students.The statistical population of the study consisted of students of faculty of art and architecture of Guilan University in 1397, among which 280 female and male students were selected by convenience sampling method. Celebrity worship attitude scale (McCutcheon et al, 2002), Cognitive flexibility inventory (Dennis & Vander Wal, 2010) and difficulties in emotional regulation scale (Gratz & Roemer, 2004) were presented to the participants. Finally, data analysis was done by SPSS-24 software using multiple regression methods.According to the results, cognitive flexibility and difficulty in emotional regulation significantly predict celebrity worship (p<0/01).According to the findings of the research, applying programs and interventions to increase cognitive flexibility and the ability of emotional regulation can reducecelebrity worship that is associated with many physical and psychological disorders and negative social and cultural consequences. Manuscript profile -
Open Access Article
185 - Study the relationship of Cell-phone Over-use and general heath in students
پریسا یاسمینژاد محسن گلمحمدیان ناصر یوسفیThis research was carried out with the purpose of Study the relationship of Cell-phone Over-use and general heath in students. The sampling group consists of 782 students in Islamic Azad universities were chosen via Cluster sampling method. The research instruments incl MoreThis research was carried out with the purpose of Study the relationship of Cell-phone Over-use and general heath in students. The sampling group consists of 782 students in Islamic Azad universities were chosen via Cluster sampling method. The research instruments including Cell-phone Over-use Scale (Jenaro & et al, 2007) and GHQ-28. multiple regression (stepwise) were used to analyze of this data. Findings indicated that, generally, the General Heath variants (four factors) have significant relationship with Cell-phone Over-use in students. Other results denoted that 4 general health factors are able to predict Cell-phone Over-use (RS=./32). The variant of "social functioning" was a more desirable predictor for Cell-phone Over-use (RS=./28). More results indicated that there is no significant difference between the Cell-phone Over-use level of the technical and humanistic students. But there is a significant difference between married - single, boy and girl students Manuscript profile -
Open Access Article
186 - Development of a psychological capital Training Package (PCTP) based on Islamic values and Assessment of its traning effect on Organizational Exellence
ahmadreza ghanbarinasrabadi Mohammadmahdi Rashidi Jamshid TaghsimiThe main objective of this research was to provide a package of psychological capital training based on Islamic values and its effect on organizational excellence on employees of Isfahan Municipality. To evaluate the statistical assumptions, test and box test were used. MoreThe main objective of this research was to provide a package of psychological capital training based on Islamic values and its effect on organizational excellence on employees of Isfahan Municipality. To evaluate the statistical assumptions, test and box test were used. In order to determine. Multivariate analysis of covariance analysis was used to investigate the effectiveness of Islamic-based psychological capital-based interventions on dependent variables. In the first stage, the research was qualitative and using Delphi technique. The data from interviews with humanities, religious scholars and ethics experts in the field of hope, self-efficacy, resilience, optimism were examined and a package of psychological capital was provided based on Islamic values. In the second stage of the study, quantitative studies were carried out and semi experimental methods were pre-test(n=60) and post-test with control group(N=3000). The results of quantitative research in two groups of control and traning in completing the “Organizational Excellence” questionnaire, Islamic psychological package showed that the mean score of organizational excellence in the experimental group in the post-test phase was more than the control group (P<0/01).Therefore, the study of Islamic psychological capital model has been able to increase the index of organizational excellence. Manuscript profile -
Open Access Article
187 - Mobile learning in environmental impact assessment training using theory of reasoned action
Seyedeh Zahra Shamsi Seyed Mohammad shobeiriIncreasing concern in various environmental issues and the need to respond to global societies transformed the use of information and communication technology into academic and academic systems into an active curriculum and curriculum. But prior to its application, the MoreIncreasing concern in various environmental issues and the need to respond to global societies transformed the use of information and communication technology into academic and academic systems into an active curriculum and curriculum. But prior to its application, the factors that affect the acceptance and use of this phenomenon should be identified. This research studies the provision of environmental education through mobile technology with research methodology, descriptive type of research based on prediction. The statistical population includes 2422905 students in Tehran during the academic year 1394, selected by stratified cluster sampling with proportional assignment. Out of the schools of this region, the 9th grade students were randomly selected to sample 350 people. To collect data, this study was conducted on the adoption of mobile learning from the questionnaire developed by Cheon et al. Validity of the questionnaire was approved by experts and experts. For reliability evaluation, Cronbach's alpha was used, which was more than 0.7 for research variables, indicating the internal reliability of the questionnaire. Data were analyzed by SPSS software and LISREL version 8.8. The findings of path analysis in the research of subjective norm, attitude and behavioral intention showed a significant role in students' desire to use mobile education technology in learning environmental education. Manuscript profile -
Open Access Article
188 - Assessing Enablers at Management Development and Transform Center of Isfahan Medical Sciences University Using Organizational Excellence Model
فرزانه اقبال سید علی سیادت محمد حسین یارمحمدیانEmpowerment in management is a strategy for change in order to improve personal and organizational capabilities. The purpose of this research was to assess the status of enablers at management development and transform center of Isfahan Medical Sciences University using MoreEmpowerment in management is a strategy for change in order to improve personal and organizational capabilities. The purpose of this research was to assess the status of enablers at management development and transform center of Isfahan Medical Sciences University using an organizational excellence model. This research was descriptive and applied which took place intervally . Research population consisted of 32 staff managers and their deputies at management development and transform center of Isfahan Medical Sciences University in the academic year 2007 who were selected randomly. The research instrument was an organizational excellence questionnaire with 26 items with reliability of 0.97. The collected data were analyzed through descriptive statistics using SPSS and RADAR logic for organizational excellence. The findings showed that management development and transform center of Isfahan Medical Sciences University has the following points: leadership (60%), strategy (80%), employees (60%), resources and partners (50%), and processes (60%) and total points gained 238 for all enablers . Manuscript profile -
Open Access Article
189 - Substrate Temperature Effect on Photovoltaic Performance of Lead Sulfide (PbS) Nanostructures Deposited by Chemical Vapor Deposition (CVD) Method
Mohsen Cheraghizade Ramin Yousefi Farid Jamali-Sheini -
Open Access Article
190 - Electrical Discharges: An Emerging Modality in Sterilization, Disinfection, and Therapeutics
Soumyadeep Sarkar Niharika Verma Pawan Tiwari -
Open Access Article
191 - Improving Code Word Interference Cancellation (CWIC) Technique in Heterogeneous Network
Maryam Yahyanezhad Simin Khazraei Shoulaifar -
Open Access Article
192 - Fault Tolerant Design of QCA Binary Wire
Mojdeh Mahdavi Mohammad Amin Amiri -
Open Access Article
193 - A New Coplanar Full Adder/Subtractor in Quantum-Dot Cellular Automata Technology
Mohsen Vahabi Amir Sabbagh Molahosseini -
Open Access Article
194 - High Level Modeling of AES in QCA Technology
Mojdeh Mahdavi Mohammad Amin Amiri -
Open Access Article
195 - A Novel method for assigning Joint power spectrum and Power Selection in device to device networks to improve performance
Anahita Jabbari S. Mahmood Daneshvar Farzanegan -
Open Access Article
196 - Designing Ultra-low-power Cardiac Pacemaker with Quantum Cellular Automation Technology
Mojdeh Mahdavi Mohammad Amin Amiri -
Open Access Article
197 - Comparison of Standards Digital Audio Encoders LPC, CELP, and MELP based on the Quality and Complexity of the Content in the Transmitted
Saeed Talati Pouriya Etezadifar Mohammad Reza Hassani Ahangar Mahdi MolazadeThis article compares the quality and complexity of LPC, CELP, and MELP standard audio encoders. These standards are based on linear predictive and are used in sound (speech) processing. These standards are powerful high-quality speech coding methods that provide highly MoreThis article compares the quality and complexity of LPC, CELP, and MELP standard audio encoders. These standards are based on linear predictive and are used in sound (speech) processing. These standards are powerful high-quality speech coding methods that provide highly accurate estimates of audio parameters and are widely used in the commercial (mobile) and military (NATO) communications industries. To compare LPC, CELP, and MELP audio encoders in two male and female voice modes and four voice models: quiet, Audio recorded without sound by the microphone, MCE, office, and two noise models 1% and 05% were used. The simulation results show the complexity of MELP is higher than LPC and CELP in terms of both processor and memory requirements. The MELP analyzer requires 72% of its total processing time. This additional memory is, of course, due to the vector quantization tables that MELP uses for the linear spectral frequencies (LSFs) and the Fourier magnitude. Also, according to the quality comparison test using the MOS index, MELP has the highest score, followed by CELP and LPC. Manuscript profile -
Open Access Article
198 - Increasing Spectral Efficiency of GFDM with Adaptive Modulation and Coding for Next Generation Cellular Networks
Farzaneh Kheirali Mohammad Hossein Madani -
Open Access Article
199 - Investigation of forest area using support vector machine and provide a model for predicting the level of changes
Armin Hashemi Amin Khademi Morteza Madanipour Kermanshahi Behrouz KordBackground and Objective Due to the increasing degradation at the level of the natural ecosystem, the amount and location of land use changes and predicting its future growth trend, I can provide the information I need to planners and managers. In this study, in order t MoreBackground and Objective Due to the increasing degradation at the level of the natural ecosystem, the amount and location of land use changes and predicting its future growth trend, I can provide the information I need to planners and managers. In this study, in order to change the current changes and predict the future in the Siahkal range, forecasting and changing the nose were done with Landsat images. There are various methods for predicting land use change. Processes for predicting and modelling land use change, such as urban growth and development, deforestation, etc., are considered powerful tools in managing natural resources and changing the state of the environment. This change reflects how humans interact with their environment, and its modelling has had an impact on settlement and macro-planning. In this research, due to the high capabilities of remote sensing and modelling tools and predicting changes in change using automatic-Markov cells in forests in northern Iran.Materials and Methods In this research, Landsat 5 images, 2000 TM sensor, Landsat 7 ETM+ sensor 2010 and Landsat 8 OLI sensor 2018 are used. In the preprocessing stage, errors in raw data such as radiometric, atmospheric, geometric, etc. errors are corrected. Was significant but had a radiometric error. 84 points are used for forest use, 76 points for thin forest water, 31 points for consumption and 2 required sensitivities to indicate a specific level of land cover. Land cover is defined into five classes: dense forest, semi-dense forest, sparse forest, urban area and agricultural area. The ENVI Remote sensing Software defines four types of kernels for the support vector machine in the SVM classification section: Polynomial, Sigmoid torsion, and FBCTION (RBF). According to the best kernel studies for land use classification, the radial kernel (RBF) has been proposed. In the present study, this kernel was used for classification. The classification of the appropriate band composition that you want to separate these classes for visual interpretation was selected by the spectral mean plot. This is done by the complex OIF index. After the extraction of land uses by the method, the results were evaluated accurately. Maps are prepared by land use, then with the GPS position of the earth, the map of the situation in the visible area and using the formed error matrix of kappa weakness and its overall accuracy obtained for this work, 200 points are randomly created on the images. The use of these points was determined by field visits and topographic maps of the surveying organization. Land use classification models are prepared, for modelling and land use changes are entered into office software to design land use changes in the required years. Degree of land use change modelling The LCM model was used in the Idrisi software environment. The Markov-CA model is a combination of automated cells, Markov chains, and multi-purpose land allocation. The Markov model also shows each user by generating a set of status probability images from the transfer probability matrix. In the last step of the structural model, using the transfer area matrix in the CA Markov model, a simulated simulation of future land use can be obtained. In this research, the land use map of 2010 and 2018 was used to predict the 2028 map. And in order to accurately review the forecast by CA Markov using the user map for 2000 and 2010, the map for 2018 has been predicted and increased by the map obtained from the classified level for this year.Results and Discussion The classification accuracy test was obtained using the Kappa coefficient index and overall accuracy. Kappa coefficient and overall accuracy were 0.88 and 0.89 for the image of 2000, 0.91 and 0.92 for the image of 2010, and 0.93 and 0.95 for the image of 2018, respectively. The images are categorized as entered into the software and processed by changing the LCM. Changes in the LCM model showed that during the years 2000 to 2018, more changes were related to the conversion of semi-dense forest land with an area of 42104.27 hectares. Urban land use change has also increased in the years of many studies and amounted to 148.14 hectares. The table of the probability of land use changes in the Markov production model and with the production map at this stage, for the years of Markov forecast studies for 2018 and 2028 showed that in 2028 the urban class area increased to 21293.1 hectares and the valuable land use area of dense forest to 2189.97 hectares will be reduced.Conclusion In order to prevent the uncontrolled expansion of cities, residential areas and the destruction of forest areas and vegetation, management measures should be taken and management decisions should be made. The level of dense and semi-dense forests in areas with high slopes will decrease further by 2028. Urban land use changes have also increased in the study years and amounted to 148.14 hectares. The results of surveying the area of forecasting classes showed that in 2028, the area of urban classrooms will increase to 21293.1 hectares and the valuable land use area of dense forests will decrease to 2189.97. The ability of the vector machine model in determining land cover/land use, vegetation and forest cover in different regions of Iran has been proven by other researchers. Remote sensing tools can be an important arm in information production in natural resource management. Manuscript profile -
Open Access Article
200 - Prediction and trendtion of land use changes and land cover using integrated methods of Markov chain and automated cells and land change modeler in Sistan plain
Zohreh Hashemi Hamid Sodaeizadeh Mohammad hossein Mokhtari Mohammad ali Hakim Zadeh Ardekani Kazem Kamali AliAbadiIn optimal planning and management of natural resources, knowledge of how land cover changes and land use and the factors that cause it are very necessary. In this field, remote sensing data have high potential to study temporal and spatial changes in land cover and lan MoreIn optimal planning and management of natural resources, knowledge of how land cover changes and land use and the factors that cause it are very necessary. In this field, remote sensing data have high potential to study temporal and spatial changes in land cover and land use. The purpose of presence study is prediction and assessment of the trend of land use changes and land cover in Zahak area of Sistan plain. For this purpose, land use and cover maps were prepared from landsat satellite images using support vector machine method of supervised classification in 1987, 2001 and 2018. Then, using the land use map in 1987 and 2001, land cover in 2018 was predicted. Land use maps for 2001 and 2018 and land cover for 2030 was predicted using integrated method of Markov chain and automated cells. To analyze the trend of land use changes and land cover since 1987- 2001, 2001- 2018 and 2018- 2030, Land change modeler was used. Results indicated that areas of watery agriculture 2013 hectares, tree cover 1117 hectares, water areas 2391 hectares and barren lands 9535 hectares has decreased since 1987- 2001. Also, the mulching area uses area 192 hectares, and sand dunes 14864 hectares were increased. During the period 2001- 2018, the areas of watery agriculture land uses 3533 hectares and barren lands 3707 hectares has decreased and uses area tree cover 313 hectares, water areas 5385, mulching area 247 hectares, and sand dunes 1295 hectares were increased. In the forecasting the time period 2018- 2030, the area of uses watery agriculture will be 1098 hectares, sand dunes 527 hectares, and barren lands 2020 hectares are reduced. In this forecast, land use of tree cover 16 hectares, water area 3607 hectares, and mulching area 23 hectares will increase. Manuscript profile -
Open Access Article
201 - Anti-Oxidative and Anti-Leukemic Effects of Methanolic Extracts of Lithospermum officinale’s Callus on Human Acute Promyelocytic Leukemia NB4 Cell Line
Parvaneh Yavari saiyed Mohammad Amin Moosavi Tahereh NajiInroduction & Objective: Although chemotherapy isa current treatment strategy for leukemia, it is usually accompanied with development of drug resistance and severe side effects. One of the possible therapeutic approaches is reducing ROS (Reactive Oxygen Species) in mal MoreInroduction & Objective: Although chemotherapy isa current treatment strategy for leukemia, it is usually accompanied with development of drug resistance and severe side effects. One of the possible therapeutic approaches is reducing ROS (Reactive Oxygen Species) in malignant cells (as anti-oxidant therapy) to inhibitproliferation of cancer cellsLOLithospermumofficinaleas an Iranian medicinal plant, has been reported as a rich source of anti-oxidantsHere, we studied anti-oxidative and anti-leukemic effects of methanol extract of this plant NB4 cell line.Material and MethodNB4 cell line was cultured and treated with different concentrations of LO extract with methanol (25-100µg/ml) in various time intervals (12-48 hours). Trypan blue exclusion test was used to evaluate growth inhibitory and viability effects of the extract on NB4 cells. Fluorescent microscopy and DNA fragmentation assay were used to study apoptosis.Results: The results showed that LOcaused growth inhibition but not apoptosis in a time- and dose-dependent manner in NB4 cells. The methanol extract of the plant could inhibit oxidative stress induced by hydrogen peroxide in NB4 cellsConclusions:Attain to anti-oxidant properties of LO, suggesting that anti-leukemic effects of the plant may mediate inhibiting ROS generationso this plant may be proposed as chemo-preventive candidate for further evaluation in cancer therapeutic approaches. Manuscript profile -
Open Access Article
202 - Comparative Evaluation Of Inhibitory Effect Of Phycocyanin (AnabaenaSp. ISC 55) and Paclitaxel on Growth 4T1 Breast Cancer Cells
Farnaz Dabbagh Moghaddam Somayeh Hamedi Mahrouz DezfulianInroduction and Objective:Breast cancer is the most common malignancy in women worldwide including Iran. Several studies have demonstrated anti-cancer and apoptotic properties of phycobili proteins from different strains of cyanobacteria phycocyanin. For the first time MoreInroduction and Objective:Breast cancer is the most common malignancy in women worldwide including Iran. Several studies have demonstrated anti-cancer and apoptotic properties of phycobili proteins from different strains of cyanobacteria phycocyanin. For the first time the aim of this study was to investigate anti-cancer effects of Anabaena sp.ISC55 phycocyanin and to compare with paclitaxel, on breast cancer 4T1cell line. Materials and Methods:After culturing cyanobacteria, phycocyanin was specifically extracted. 4T1 breast cancer cells were cultured. Colony forming assaywas performed and cytotoxicity of different concentrations (250- 200- 175-150- 125-100- 75-50- 25-20- 15-10)mg/ml of phycocyanin and paclitaxel was tested by MTT assay and adhesion test after 24 hours incubation with cultured cells. The effects of these concentrations on the morphological features of cells was evaluated under inverted microscope. Data were analyzed using one-way ANOVA followed by Tukey's multiple comparison test as post hoc. Results:The results indicate an increase in anti-cancer properties phycocyanin in high concentrations by increasing apoptosis with a significance level of P Conclusion:According to the results, Anabaena sp.ISC55 phycocyanin has dose dependent anti-cancer properties. Manuscript profile -
Open Access Article
203 - Resistance training with nanocurcumin on IL-4 and STAT-6 gene expression in muscle cells of healthy male rats
Sadra Sheidaei Shahin Riyahi Malayeri Masoumeh Hosseiniزمینه و هدف: محور پیامدهی IL4/STAT-6 یکی از مهم‏ترین مسیرهای مهم درگیر در رشد و توسعه سرطان میباشد. هدف از پژوهش حاضر بررسی تاثیر تمرین مقاومتی همراه با مصرف نانوکورکومین بر IL-4 و STAT-6 در سلول های ضلانی رت های نر سالم بود. مواد و روش ها: در این مطالعه تجربی، 32 Moreزمینه و هدف: محور پیامدهی IL4/STAT-6 یکی از مهم‏ترین مسیرهای مهم درگیر در رشد و توسعه سرطان میباشد. هدف از پژوهش حاضر بررسی تاثیر تمرین مقاومتی همراه با مصرف نانوکورکومین بر IL-4 و STAT-6 در سلول های ضلانی رت های نر سالم بود. مواد و روش ها: در این مطالعه تجربی، 32 سر رت نر نژاد ویستار به طور تصادفی به چهار گروه (کنترل، تمرین مقاومتی، نانوکورکومین، تمرین مقاومتی+ نانوکورکومین) تقسیم شدند. برنامه تمرینی به مدت 4 هفته و 3 جلسه در هر هفته اجرا شد. گروه های دریافت کننده مکمل روزانه 80 میلی گرم نانوکورکومین به ازای هر کیلوگرم وزن بدن به مدت 4 هفته به صورت خوراکی (گاواژ) دریافت کردند. بیان ژنIL-4 و STAT-6 با روش Real-time PCR اندازه گیری شد. داده ها با استفاده از آزمون تحلیل واریانس یک طرفه مورد بررسی قرار گرفتند.یافته ها: نتایج نشان داد تمرین مقاومتی همراه با مصرف نانوکورکومین موجب افزایش معنادار IL-4 نسبت به سایر گروه ها و کاهش STAT-6 نسبت به گروه تمرین سلول عضلانی رت های نر سالم شد(05/0>P ).نتیجه گیری: به نظر می‏ رسد چهار هفته تمرین مقاومتی همراه با مصرف مکمل نانوکورکومین احتمالا با تاثیر بر محور پیام دهی IL-4/STAT-6 می تواند به تنهایی در روند کاهش آن موثرتر باشد. Manuscript profile -
Open Access Article
204 - Protective effects of Silymarin on Cell-Phone Induced Liver Damage in Rats
ََAmir Ashkan MahjoorInroduction & Objective: Different studies have demonstrated the effects of cell phone induced electromagnetic field on hepatic cells. The aim of this study was to investigate the hrpatoprotective effects of silymarin on this kind of damagesMaterial and MethodsSeventy r MoreInroduction & Objective: Different studies have demonstrated the effects of cell phone induced electromagnetic field on hepatic cells. The aim of this study was to investigate the hrpatoprotective effects of silymarin on this kind of damagesMaterial and MethodsSeventy rats were divided in five groups. One control group and four exposure groups that were exposed to cell phone radiation 5 times a day for 30 days each time 10 minutes. At the end of the study all of the rats were sacrificed and Alanine Aminotransferase (ALT), aspartate aminotransferase (AST) and Alkaline Phosphatase (ALP), total proptein, total bilirubin and albumin were measured. Liver samples were obtained for histopathological studiesResults: Cell phone radiation significantly (P≤005) increased levels of ALT, AST, ALP, total bilirubin and decreased levels of total protein and albumin. In groups treated with silymarin improve in biochemical factors were noted. Histopathological findings were consistent with biochemical findingsConclusion:Our results suggest that silymarin has hepatoprotective effects on cell phone induced liver damaged due to free radical scavenger and antioxidant Manuscript profile -
Open Access Article
205 - Evaluation Of Cytotoxic Effect Of Aqueous andHydroalcoholic Extracts Of Guava Fruit Psidium guajava L on Cell Line DU-145
Sholeh Zaeemi Baravati کهین شاهانی پور Ramesh MonajemiInroduction and Objective:Prostate cancer is the second most common cancer in men after skin cancer. Guava Fruit with scientific name Psidium guajava L. are considered as an important source of phenolic compounds and antioxidant effect.In this study, the cytotoxic effec MoreInroduction and Objective:Prostate cancer is the second most common cancer in men after skin cancer. Guava Fruit with scientific name Psidium guajava L. are considered as an important source of phenolic compounds and antioxidant effect.In this study, the cytotoxic effect of aqueous and hydroalcoholic extracts of Guava fruit and effect of the extracts on DU-145 cell line was and its effect on prostate cancer cells was studied. Materials and Methods:Guava fruit was collected from Sistan and Baluchestan region. The aqueous and hydroalcoholic extracts were prepared from this plant. Class of DU-145 cells was cultured in RPMI-1640 medium containing 10% bovine serum in a 5% CO2 incubator, and under different concentrations of aqueous extract of 24, 48 and 72 hours were incubated. MTT assay for cell survival in the presence and absence of extract was used to calculate the percentage and absorbance at 540 nm was measured by ELISA. Data were assessed using SPSS software(* = P-value Results:The results showed that the aqueous and alcoholic extract Guava fruit is a cytotoxic effect. Further studies showed that the cytotoxic effect of aqueous extracts of the ethanol extract is much stronger. Manuscript profile -
Open Access Article
206 - Isolation Of Bacillus cereus from Foods and Studying the Cytotoxicity Of Them on Vero Cells
Zahra Deilami Khiabani Shahrzad Nasiri SemnaniInroduction and Objective:Bacillus cereusis an important enterotoxigenic food borne pathogen. It contains NHE and HBL complex enterotoxins. The genes of these complex can be used for characterization of enterotoxin production in B. cereus. The objective of this study MoreInroduction and Objective:Bacillus cereusis an important enterotoxigenic food borne pathogen. It contains NHE and HBL complex enterotoxins. The genes of these complex can be used for characterization of enterotoxin production in B. cereus. The objective of this study is to detect enterotoxigenic B. cereus and assessing the incidence of it in foods.Material and Methods:220 food samples including; 80 meat products, 20 dairy, 20 rice and 100 salad samples, have been collected in the years 2012-2014. Using biochemical and molecular tests, the B. cereus positive food samples has been detected. B.cereus isolates checked for NHE and HBL complex by specific primers. B. cereus isolates which contain both NHE and HBL have been used for cytotoxic assay on Vero cells.Results: Among 100 B.cereus isolates, 40 contain NHE, 23 contain HBL and 17 isolates contain both complexes. The recent isolates have been used for cytotoxic assay on Vero cells.Conclusion: PCR is a prompt, reliable method for detection of enterotoxigenic bacteria. Enhancing awareness about virulence and prevalence of genes involved in food poisoning would be effective in prevention of food poisoning. Manuscript profile -
Open Access Article
207 - Assessment of CXCL12 Gene Expression in HumanLung Adenocarcinoma Cell Line A549by Real Time PCR Method
Rayhaneh Mahbubi Jalil Fallah Mehrabadi Elaheh Ali AsgariInroduction & Objective: Lung cancer is the most common malignancy and the leading cause of cancer related mortality among women and men worldwide, in such a way that the 5-year survival of patients is about 15%. According to the invasive role of CXCL12, challenges in v MoreInroduction & Objective: Lung cancer is the most common malignancy and the leading cause of cancer related mortality among women and men worldwide, in such a way that the 5-year survival of patients is about 15%. According to the invasive role of CXCL12, challenges in various studies about expression and non-expression of CXCL12 and the presence of metastasis in early stages of lung adenocarcinoma, the A549 cell line is selected in order to investigate CXCL12 gene expression in it.Material and Methods:In this study A549 cell line was cultured in a DMEM medium contain 10% fetal serum bovine and 1% penicillin- streptomycin. RNA extraction was performed from the mentioned cell line and after qualitative and quantitative evaluation of extracted total RNA, cDNA was synthesized. Then CXCL12 expression was measured using Real time PCR.Results: CXCL12 low expression in lung adenocarcinoma A549 Cell line shows that it can be considered as a potential markerfor predictive and therapeutic purposes.Conclusion:CXCLL12 has a low expression in A549 cell line. Manuscript profile -
Open Access Article
208 - Effects Of Different Levels Of Bactocell Supplemented with Diet on Some Immunological Parameters in Rainbow Trout (Oncorhynchus mykiss
Mohammad Reza Behroz Khoshghalb Ghobad Azari Takami Hossein Khara Rezvanollah KhazemiInroduction and Objective:The effects of the probiotic, Pediococcus acidilactici, commercially known as Bactocell on some immunological parameters in the fingerlings of rainbow trout, Oncorhynchus mykissMaterials andMethods:A total of 3600 fingerlings with an average we MoreInroduction and Objective:The effects of the probiotic, Pediococcus acidilactici, commercially known as Bactocell on some immunological parameters in the fingerlings of rainbow trout, Oncorhynchus mykissMaterials andMethods:A total of 3600 fingerlings with an average weight between 3 and 5 g were randomly stocked in equal numbers in 12 channels. Three experimental feeds comprising 100, 200 and 300 g of bactocell per ton feed and one control feed were tested in three replicates while the experiment lasted 8 weeks. Fish were fed three times a day and feeding rates were adjusted to their body weight and water temperature. Five fish were randomly selected from each group at the end of the forth week and at the end of the eighth week and blood samples were collected and analyzed for Biochemical analyses and also conducted to determine levels of lyzozyme enzyme (lgM), total protein, complement CH50, SGOT, SGPT and glucose .Results:Results obtained from this study indicate that increase in concentration of levels of lyzozyme enzyme, immune globulin and compliment CH50 , Albumin and total protein in treatments which contain probiotic Bactocell than those found in the controls treatments .Conclusion:Increasing of those enzymes in blood serum of fingerlings is an indicator of immune system activities that could cause increase in the resistance of rainbow trout fingerings towards pathogenic factors and environmental stimuli Manuscript profile -
Open Access Article
209 - The Synergic Effects Of Shell Extract Of Persian Gulf ChitonLamyiand Acellular Brain on Angiogenesis in Chick Embryo Chorioallantoic Membrane
جواد بهارآرا تکتم جوان جعفری بجنوردی ناصر مهدوی شهری سعیده ظفربالا نژادInroduction and Objective: Chitons are important for medical research because exist of chitosan and chitin in itʼs shell. Because of importance of angiogenesis and since Angiogenesis is a complex process involving extensive interplay between cell soluble factors and ext MoreInroduction and Objective: Chitons are important for medical research because exist of chitosan and chitin in itʼs shell. Because of importance of angiogenesis and since Angiogenesis is a complex process involving extensive interplay between cell soluble factors and extra cellular matrix (ECM) components. In this study, we investigated the angiogenic response induced by Synergic effects of chitonʼs shell extract and acellular brain scaffolds implanted onto the chick chorioallantoic membrane.Materials and Methods In this experimental study, the rat brain was decellularized. we used 50 fertilized eggs that were divided into 5 groups: control, sham-exposed1, sham-exposed2, experimental 1,and experimental 2. In the 12nd day of incubation, the numbers and lengths of vessels around the sponges were measured by Image J software, data were analyzed with SPSS (version 16) and by statistic test such as ANOVA and Tukey results in significant level PResults: Mean number(10/34 ± 1/85) and length(13/12±2/04mm) of vessels in the control with number(6/06±1/36) and length(9/76±1/21mm) of vessels in the experimental group 1 showed a significant decrease (p Conclusion:Results indicate that synergic usage of shell extract of Chiton Lamyi and acellular brain decrease angiogenesis in chorioallantoic membrane Manuscript profile -
Open Access Article
210 - Effect Of Intraperitoneal Injection Of Quince Seed’s Extracts on Biochemical and Hematological Parameters in Mouse
حسین حمزه ئی حامد علیزاده عطیه مهدوی نرمین جاورIntroduction and Objectiv:Recently herbal plants were used extensively in various fields, especially in the control of bacterial infections. But the toxicity of probably side effects caused very concern in the use of these materials in various fields of medicine. The ai MoreIntroduction and Objectiv:Recently herbal plants were used extensively in various fields, especially in the control of bacterial infections. But the toxicity of probably side effects caused very concern in the use of these materials in various fields of medicine. The aim of this study was clarify some of these ambiguities and investigation the effect of injection of Quince seed’s extracts on mouse biochemical and hematological parameters.Material andMethods:Recently herbal plants were used extensively in various fields, especially in the control of bacterial infections. But the toxicity of probably side effects caused very concern in the use of these materials in various fields of medicine. The aim of this study was clarify some of these ambiguities and investigation the effect of injection of Quince seed’s extracts on mouse biochemical and hematological parameters.Results:The results showed no significant changes in biochemical factors. Blood parameters includes: white blood cells, red blood cells, platelets, hemoglobin and hematocrit percent don’t show any variation. Platelet levels increased slightly in the experimental mice.Conclusion:Intraperitoneal injection of Quince seed’s extracts in mice does not affect biochemical and hematological factors Manuscript profile -
Open Access Article
211 - The Study Of the effect Of ovine bladder scaffold Of sheep, ِDomesticated breed, on blastema cells in vitro
نگار صغیری هاشم راستی جواد بهارآرا ناصر مهدوی شهری مهدی مرجانی سید حسن علوی فاطمه علویIntroduction and ObjectiveBiological scaffolds, composed of Extra Cellular Matrix (ECM), are capable of facilitating the restructuring of a large number of tissues. The objective of this study was to investigate the effect of ovine bladder scaffold of sheep, domesticate MoreIntroduction and ObjectiveBiological scaffolds, composed of Extra Cellular Matrix (ECM), are capable of facilitating the restructuring of a large number of tissues. The objective of this study was to investigate the effect of ovine bladder scaffold of sheep, domesticated breedon blastema cells in vitroMaterials and Methods: At first, ovine bladder o the sheep was decellularized by putting in 1% wt/vol solution of sodium dodecyl sulfate (SDS) for 24 hours. Then to prepare the blastema tissue, the pinna of New Zealand rabbit was manually punched-hole with a special puncher and a circular blastema was separated. There after, the decellularized samples were put in the middle of blastema ring and were transfered to the culture medium. To continue the study, microscope with lights of hematoxylin and eosin and pick indigo and Toluidine blue staining was used. Some samples on the day 15 and 20 of culture were studied by transitional electron microscope.Results: Collagen fibers were preserved after decellularized in matrix of bladder. Most migration of blastema cells occurred on days 15 and 20 of culture. On the day 10 and 15, some immature cells were differentiation in the pathway of adipocyte and fibroblast. On the day 15th and 20th, more blastema cells were migrated to the ovine scaffold. On the 10th and 15 day immature cell culture was seen to be differentiated from fibroblast and adipocyte cells. On the 15 th day blastema cell culture differentiated from covering cells and on the 20th day from fibroblast and adipocyte cells were seen.Conclusion: Bladder scaffold has ability to induce blastema cells and causes not only blastoma cells’ migration but also to be changed to different cells. This phenomenon is very important because of no growth factor and inducer was used in culture medium. Manuscript profile -
Open Access Article
212 - The study Of the effects Of Probiotic Yeast Cell Wall (Saccharomyces cerevisia) on Changes in blood indices and Immunity Of Rainbow Trout Fry (Oncorhynchusmykiss
محمد اعتصامی پور عباسعلی زمینی مسعود فرخ روزInroduction and Objective: Prebioticdietary supplements that have the potential to reduce the harmful effects of infectious agents and have beneficial effects on host health. In this study, the prebiotic of yeast cell wall Saccharomyces cerevisiaat different levels to e MoreInroduction and Objective: Prebioticdietary supplements that have the potential to reduce the harmful effects of infectious agents and have beneficial effects on host health. In this study, the prebiotic of yeast cell wall Saccharomyces cerevisiaat different levels to evaluate the blood indices and immune indices in rainbow trout juveniles were used.Materials and Methods:To conduct this study, 120 rainbow trout fry with a mean weight 3.61± 0.12 gr were randomly assigned into 12 fiberglass tub drainage volume of 100 ml distribution and breeding were given. An experiment to determine the optimum level of prebiotic effect of dietary yeast cell wall in the diet of rainbow trout fry in 1% prebiotic treatments, 1.5% prebiotic, 2% prebiotic prebiotic-free control, in a balanced design with three replications each were studied. At the end of the period rearing, blood indices and immune indices juveniles were studied.Results:The results of some blood indices such as levels of White blood cells, Red blood cells, hemoglobin and hematocrit levels and neutrophil counts were not significantly different between the treatment and control groups were observed in 2% and other treatments (P0.05). The results showed that non-specific immune indices in blood, such as lysozyme and specific immune IgM and Ig statistically significant difference between treatment groups fed with 2 % prebiotic yeast cell wall with the other treatments and the control group (PConclusion: Based onthese results it can be stated that the level of 2% prebiotic yeast cell wallused in thediet caused a significant increase in immune indices , andsomeblood parametersof studied, An important rolein immune function and improve blood indices of rainbow trout fry can play Manuscript profile -
Open Access Article
213 - Effects Of Bactocell Probiotic (Pediococcus acidilactici) and Folic AcidonImmune System onShip Sturgeon Fingerling
Neghin Delsoz Khaki Hossein Kara Mahmoud Mohseni ََAlireza Shenavar MasolehInroduction and ObjectiveShip sturgeon is belonged to sturgeon species which is suitable for cultivation. Probiotics are useful effects on the health and the growth of host. This study was conducted to determine different levels of one commercial probiotic (pediococcus MoreInroduction and ObjectiveShip sturgeon is belonged to sturgeon species which is suitable for cultivation. Probiotics are useful effects on the health and the growth of host. This study was conducted to determine different levels of one commercial probiotic (pediococcus accidilactici) in the thesis, also the effect of folic acid on immune system (Acipenser nudiventirisMaterials and Methods:210 fish of this breeding kind with the dentisty of 10 pertub fiber glass in 7 dietary treatments for 8 weeks fedup for third times, respectively, treatment 1(4mg acid folic in mercury), treatment 2(probiotics of 300 g of per tone of food), treatment 3(4mg acid folic, 200g probiotics), treatment 4(2mg acid folic,300g probiotics), treatment 5(2 mg acid folic,200g probiotics), treatment 6(4mg acid folic,300g probiotcs).treatment7 (control).Results:The numbers of control leukocyte, in control to other treatment had significant change or difference, and its maximum was for treatment 6. Eosinophils had no significant change or difference in all treatments, but the minimum amount of neutrophils and the maximum of lymphocyte amount were observed in host. The maximum numbers of RBC and hemoglobin, hematocrit were seen in treatments regards to treatment 6, which had significant difference from others, and the least index was observed in host, which had significant difference from other treatments. MCH, MCHC of treatments showed no significant difference, but the maximum of MCV for treatment 4 was seen which had significant difference. The average amount of lysozyme for treatment6 and 5, was the maximum amount, which had statistical difference from others treatments. the maximum amountof immunoglobulins was, respectively, treatment 4and6 and the maximum amount of IgM for treatments 5and6 were observed, which had significant difference from others.Conclusion:According to these result, we can acknowledge that adding treatment 6 in per ton food, cause breeding growth and the effectiveness of food which plays a positive role Manuscript profile -
Open Access Article
214 - Study Of Cytotoxisity Effects Of Aqueous Extract Of Physalis. alkekengi Against U937 Cell Line
Parvin Torabzadeh Mahroz DezfulianIntroduction and Objective:Physalis-alkekengiof Solanaceace has been recommended as a traditional antipyretic, antineoplastic, anti inflammation, analgestic, anti bacterial, anti virus and anti tumor drug by herbalist in Iran. For this purpose we decided to study cytoto MoreIntroduction and Objective:Physalis-alkekengiof Solanaceace has been recommended as a traditional antipyretic, antineoplastic, anti inflammation, analgestic, anti bacterial, anti virus and anti tumor drug by herbalist in Iran. For this purpose we decided to study cytotoxic effects of the aqueous extract of it on the U937 Cell.Materials and Methods:At first, the aqueous extracts of the plant were obtained. Then three different doses of this extract (low, medium and high) were effected on U937, Hela and L929 cell cultures, and by MTT Assay viability of this cells were evaluated.Results:The results show that significant difference was observed in surviving of U937, Hela and L929 cells, when control group and treated group was compared.The LC50 for the U937 cells was28.125 mg/ml.ConclusionThe results discovered that aqueous extracts of the Physalis-alkekengi have good cytotoxic effects on U937 cells. Manuscript profile -
Open Access Article
215 - Evaluation Of the Effects Of Different Concentrations Of Aloe veraExtract on the Proliferation Of Uterus Cervical Cancer Cells(Hela)Of Humans
Elahe Ebrahimi Masoud Parsania Hamid Hosseini dostInroduction and Objective: Cervical cancer is the second most common cancer in womenHigh incidence ofcerviccancer and the side effects of the treatments with synthetic chemical compounds demonstrated that hazards are immense.Considering the side effects, treatment with MoreInroduction and Objective: Cervical cancer is the second most common cancer in womenHigh incidence ofcerviccancer and the side effects of the treatments with synthetic chemical compounds demonstrated that hazards are immense.Considering the side effects, treatment with extracts of plants such as Aloe vera have proved to be reducing the levels of side effects and can bemuch cheaper alternative. So, anti cancer properties of the extracts of Aloe vera against the Hela cells of humanwas evaluated in tissue culture, in this study.Material and Methods:After gatheringand confirmthe desiredplant species.Extractionwas performed bymacerationThe toxicity effects of different concentrations 16,17,18,19, 20 and 21 mg/ml of extract of Aloe veraon the Hela cells of human, were evaluated using Trypan blue and MTT methods,on 24, 48 and 72 hours after exposure to a mediumcontaining 1serum and extractResults: 20 mg/ml concentration ofAloe veraextract was toxical effects on Hela cells of human based on the results obtained, it was concluded that extracts of Aloe verainhibit the proliferation of Hela cells of human Manuscript profile -
Open Access Article
216 - Amplification Of vh and vl Gene Fragments from RNA Source Of Single Human Plasma Cell
Laya Esmati Jalil Fallah Mehrabadi Hamideh Rouhaninejad Masomeh BazazInroduction and ObjectiveThe first generation of therapeutic monoclonal antibodies was isolated from mouse. One of the disadvantages of them was stimulating immune response in human. Fully human monoclonal antibodies are significantly considered due to their high effici MoreInroduction and ObjectiveThe first generation of therapeutic monoclonal antibodies was isolated from mouse. One of the disadvantages of them was stimulating immune response in human. Fully human monoclonal antibodies are significantly considered due to their high efficiency and low immunogenic potential. Nowadays different kind of techniques such as phage display and single B cell technology are used to produce fully human mAb. The aim of this project was amplification of VH and VL genes from RNA source of Human plasma cell.Materials and Methods:With the aim of isolation and amplification of VH and VL regions, single cell RT-PCR reaction was performed. Single plasma cells were lysed by using cell lysis buffer. By using synthesized cDNA from plasma cells and antibody specific primers, antibody genes were amplified. Six pair of primers utilized to amplify the variable region of heavy chain (VH) and light chain (VL). Restriction sites and the linker sequences were placed on primer sequences due to respectively cloned in target plasmid and to link VH and VL. Results: Electrophoresis represented VH and VL fragments with 400 bp length were amplified by PCR. The VH and VL gene sequences were BLAST separately and showed 97% similarity among other antibodies gene sequence.Conclusion: Primer sets were selected and designed which contain linker sequence for ScFv construction, NcoI and NotI restriction sites in order to clone directly into an expression vector. Manuscript profile -
Open Access Article
217 - The Role Of TNF-α in the Pattern Of CXCR4 Gene Expression in Human Bone Marrow-Derived Mesenchymal Stem Cells
Rozita Ziaei Maryam Ayatollahi رامین یعقوبی زینب صحرائیان نصرت الله ضرغامیInroduction and ObjectiveMigration and engraftment have a vital role in tissue regeneration and transplantation and CXCR4 is a known chemokin receptor in making and increasing homing and engraftment of cells into damaged tissue or wounds. CXCR4 expresses in low level on MoreInroduction and ObjectiveMigration and engraftment have a vital role in tissue regeneration and transplantation and CXCR4 is a known chemokin receptor in making and increasing homing and engraftment of cells into damaged tissue or wounds. CXCR4 expresses in low level on human MSCs, but we show here that CXCR4 expression by hBM MSCs up-regulates through exposure to TNF-α in a dose and time dependent manner.Materials and Methods:Cultured hBM MSCs were divided into 9 groups. One group was un treated and the others treated with 1 ng/ml and 10 ng/ml TNF- α in 2, 10, 24 and48 hours. Total mRNA was extracted and cDNA synthesized. Then rate of CXCR4 expression compared with housekeeping gene (β-actin) by Real Time PCR.Results: In untreated hMSCs CXCR4 expressed in low level. In treated hMSCs with 1ng/ml TNF-α in 2, 10, 24 and 48 hours CXCR4 expression was increased respectively 32, 64, 256,32 fold and with 10ng/ml increased 16, 32, 512, 32 fold. The highest level of CXCR4 gene expression found after treatment with 10ng/ml TNF-a in 24h was highly increased(2-∆∆Ct = 512 ).Conclusion:These finding indicate that in vitro control of both dose and time factors may be important in future-stem cell transplantation therapies Manuscript profile -
Open Access Article
218 - The Study Of the Effects Of Dexamethasone during Pregnancy on development and Function Of Ovary Tissue Of adult in Offspring Of First Lineage Rats
مریم مشفقی سید ابراهیم حسینی اکبر وحدتی زینب مشفقیIntroduction and Objective: Dexamethasone is a synthetic glucocorticoid that is used in medical sciences for treating many disorders suchovulation. Therefore, the present study investigates, the effect of prescribe of dexamethasone during pregnancy on function of pi MoreIntroduction and Objective: Dexamethasone is a synthetic glucocorticoid that is used in medical sciences for treating many disorders suchovulation. Therefore, the present study investigates, the effect of prescribe of dexamethasone during pregnancy on function of pituitary-gonadal axis and number of ovary follicles of offspring of female rats.Materials and Methods: In this study, the researcher selected 40 pregnant rats that divided into control groups, sham group, and 3 experimental groups receiving 0.5, 1, and 2 mg/kg doses of dexamethasone, administered from the eighth day until the end of pregnancy QOD. After delivery, niether infants nor mothers received not no treatment. After puberty of female one, heart sampling was done and their ovary was separated and tissue section was taken, then plasma rate of strogen, progestron, FSH, LH and the number of ovary follicle were measured. Results were analysed with the SPSS software (V. 20) and ANOVA and Duncan test. (p≤0.05).Results: Results of statistical analysisshowed that dose dependent dexamethson causes decreases estrogen, LH and increases progesterone, FSH and decreases the number of ovary follicle.Conclusion: Dexamethasone via inhibition of LH secretion and impairment of fetal ovarian development causes stable reproductive disorders in female rats. Manuscript profile -
Open Access Article
219 - The Expression Of Neurogenin-3 in Adult Pancreas human
Anahita ُShaer Neghar Azarpira Mohammad Hosain Karimi Mehrdad ShariatiInroduction and Objective: Neurogenin-3 is a protein that in humans is encoded by the NEUROG3 gene. Neurogenin-3 is expressed in endocrine progenitor cells and is required for endocrine cell development in the pancreas and intestine. Ngn3 expression peaks during the maj MoreInroduction and Objective: Neurogenin-3 is a protein that in humans is encoded by the NEUROG3 gene. Neurogenin-3 is expressed in endocrine progenitor cells and is required for endocrine cell development in the pancreas and intestine. Ngn3 expression peaks during the major wave of endocrine cell genesis is greatly diminished at birth and is largely absent from the mature pancreas.Materials and Methods: Total RNA was extracted from adult human pancreatic tissue using Mini-RNease RNA extract kit. PCR was used to identify the gene expression on Neurogenin-3 in adult Pancreas.Results: RT-PCR analysis showed Neurogenin-3 gene expression.Conclusion:NGN3 is transiently expressed in endocrine progenitor cells when the pancreas developed in the human embryo. But in this study we showed that NGN3gene expresses in adult human Pancreas. Probably the endocrine progenitor cells present within human adult pancreas and maybe NGN3gene expresses after any major organ insult. Manuscript profile -
Open Access Article
220 - Gene expression pattern Of insulin-like growth factor–i receptor induced by tumor necrosis factor-αin human bone marrow derived mesenchymal stem cells
Zainab Sahraiyan Maryam Ayatollahi Ramin YaghobiInroduction and ObjectiveAcute liver failure (ALF) is a severe liver injury accompanied by sustained liver damage. It is imperative that new approaches for repairing the liver are developed. Cell-based therapy has been implicated in the treatment of liver diseases. Mese MoreInroduction and ObjectiveAcute liver failure (ALF) is a severe liver injury accompanied by sustained liver damage. It is imperative that new approaches for repairing the liver are developed. Cell-based therapy has been implicated in the treatment of liver diseases. Mesenchymal stemcells (MSCs) from various sources such as bone marrow are available. These cells are one of them ajorcandidates incell therapy.The production of insulin-like growth factor-I (IGF-I) increases in the regenerating liver. The IGF-I in liver regeneration is effective after binding to insulin-like growth factor-I receptor (IGF-IR).We hypothesized that tumor necrosis factor-αstimulate MSCs to cause IGF-IRexpression.Materials and Methods:Bone marrow was aspirated fromhuman normal donor after informing consent. Cells were isolated and cultured. Identification of cells with flow cytometric analysis was performed. Fourth passage cells were treated with tumor necrosis factor-α (TNF-α)at 1 ng/mL doseand incubated at different times (2, 10, 24 and 48 hours).The IGF-IRgene expression was investigatedusing real time-polymerase chain reaction technique.Results: Flow cytometric analysis showed that the human bone marrow MSCs were positive for CD90 and negative for CD45 and CD80.The IGF-IRgene expression was increased in TNF-α treated in comparison with untreated cells.Conclusion:Increase gene expression pattern of IGF-IR in human bone marrow derived MSCs may be used for clinical stem cell therapy in ALF. Manuscript profile -
Open Access Article
221 - Evaluation Effect Of Methanol Extract Of Brittle Stars Persian Gulf In Vitro
Sajjad Farrokhyar Javad Bahar Ara Faredeh Namvar Morteza Behnam Rasoli Tayebe RamazaniInroduction and Objective:Natural products have fewer side effects than synthetic drugs and their preparation is much easier. Brittle sea stars contain ingredients such as saponins, naphtoquinone. This materials are active in inflammatory conditions. In this study the e MoreInroduction and Objective:Natural products have fewer side effects than synthetic drugs and their preparation is much easier. Brittle sea stars contain ingredients such as saponins, naphtoquinone. This materials are active in inflammatory conditions. In this study the effects of methanol extract of Brittle Stars was evaluated.Material and Methods:The anti-inflammatory activity of methanol extract of Brittle star was assessment by denaturation of albumin, erythrocyte membrane stabilization and inhibition of proteinase activity assays. As standard anti-inflammatory drug aspirin was used. Brittle stars extract in concentrations 100, 200, 300, 400 µg / ml was prepared. Data was obtained analyzed using SPSS statistical T test at in significant level of the PResults: The results exhibited that total methanol extract of Persian Gulf Brittle star has anti-inflammatory effects so that suppressed denaturation of albumin at a concentration of 300ug/ml. also it caused cell membrane stability of red blood cells and avoided the proteinase activity at a concentration of 400ug/ml and concentration of 400 ug/ml, respectivelyConclusion: The results showed that the brittle stars have anti-inflammatory effects , thus this marine natural product can consider as a suitable candidate for more study in common inflammatory diseases. Manuscript profile -
Open Access Article
222 - Comparison of the effect of exosomes derived from Sertoli cells with vitamin C on damage induced by electromagnetic field (50 Hz) in spermatogonial stem cells
Farzaneh Salek Javad Baharara Khadijeh Nejad Shahrokhabadi Elaheh AminiIntroduction & Objective: Spermatogonial stem cells (SSCs) as adult stem cells are crucial for spermatogenesis. Electromagnetic fields (EMF) leads to biological activity disruption of these cells and spermatogenesis. Antioxidants like vitamin C can reduce the damage MoreIntroduction & Objective: Spermatogonial stem cells (SSCs) as adult stem cells are crucial for spermatogenesis. Electromagnetic fields (EMF) leads to biological activity disruption of these cells and spermatogenesis. Antioxidants like vitamin C can reduce the damage caused by EMF through oxidative stress reduction. Recent studies also reported the key role of Sertoli cell paracrine signaling in regulating the maintenance and differentiation of SSCs. Thus, we examined and compared the effect of vitamin C and exosomes derived from Sertoli cells on damage induced by EMF in SSCs. Material and Methods: SSCs and Sertoli cells were isolated from the testes of immature male mice. The alkaline phosphatase activity of SSCs was investigated. SSCs were exposed to 50 Hz EMF intensity of 2.5 mT for one hour/five days and were treated with the optimal concentration of vitamin C and various concentrations of exosome. Then the rate of viability, colonization capacity, and apoptosis of these cells were examined. Results: Our results showed the destructive effect of EMF by reducing viability, colonization rate and alteration of SSCs nuclei. Also, these results were confirmed by increasing expression level of Caspase 9 as apoptotic gene and down-regulation of SOD as antioxidant gene. The addition of vitamin C and exosomes improved the alterations induced by EMF in SSCs; however exosomes had more ameliorative effect in comparison with vitamin C on these alterations. Conclusion: These findings demonstrated the capacity and effectiveness of exosomes as a new therapeutic agent that can restore SSCs microenvironment damaged caused by EMF exposure. Manuscript profile -
Open Access Article
223 - The Effects of Wharton's Jelly Mesenchymal Stem Cells Associated with Gum of Pistacia atlanticafor Burn Wound Healing
الهام حویزیBackground: Burn is a common wound in the world and consider the novel methods such as cell therapy can be a helpful strategy in the treatment. The purpose of the present study is investigating the effects of using ointment of animal oil mixed with Gum of Pistacia atlan MoreBackground: Burn is a common wound in the world and consider the novel methods such as cell therapy can be a helpful strategy in the treatment. The purpose of the present study is investigating the effects of using ointment of animal oil mixed with Gum of Pistacia atlantica associated wharton's jelly mesenchymal stem cells (WJMSCs) on rat third-degree burn models. Methods:In this experimental study, WJMSCs were extracted from human umbilical cord. For this study, 28 Wistar rats were burned by heating a metal rod of 1cm in diameter and then randomly divided into the control (7 rats) and treatment (21 rats) groups. The treatment group was divided into three groups (each group of 7 rats) of daily scrubbingof ointment, cell therapy, and cell therapy+ ointment. 106 cells (passage3) were injected into each rat subcutaneously. On day 30 after treatment, animals killed by chloroform and histological sections were prepared by staining Hematoxylsene-Eosin (H&E) and Trichromosone done for microscopic study. Results: Macroscopic and microscopic results indicated that in the experimental groups, the recovery was significantly more than the control. Also, the cell therapy+ ointment was significantly more effective than ointment and cell alone after 30 days. Histological analysis demonstrated a significant increase in angiogenesis, collagen synthesis, number of cells, thickness of skin layers, and totally acceleration wound healing in experimental groups compared to controls. Conclusion: Based on these data, it can be suggested that simultaneous cell-therapy and traditional medicine accelerate the repair of skin burns in the animal models more significantly. Manuscript profile -
Open Access Article
224 - Effect of Tilia platyphyllos L. extract on the sex hormones levels and histopathology index in varicocele-induced infertile rats
Reihaneh Mohebali Akram Eidi Pejman Mortazavi Mohammad Amin EdalatmaneshBackground and Aim: Varicocele is one of the most common causes of infertility in men. Various studies have been performed on the treatment of varicocele and hormonal changes in the testicles. One of the non-invasive treatments for varicocele is treatment with Tilia pla MoreBackground and Aim: Varicocele is one of the most common causes of infertility in men. Various studies have been performed on the treatment of varicocele and hormonal changes in the testicles. One of the non-invasive treatments for varicocele is treatment with Tilia platyphyllos L. as a medicine used to treat stomach ulcers, spasms and sedatives. Chemical compounds such as terpenoids and flavonoids have been identified in the linden. The aim of this study was to evaluate the effect of linden extract on testicular pathology of healthy and varicocele rats.Materials and Methods: In this study, 48 rats were randomly divided into 8 groups: healthy control, healthy groups receiving linden extract (50, 100 and 200 mg / kg intragastrically, daily) alone, infertile control (varicocele surgery), varicocele groups together with linden extract (50, 100 and 200 mg / kg intragastrically, daily). After 60 days, serum was obtained and hormonal assays and histopathological examinations were performed and the data were analyzed using one-way analysis of variance.Results: The results showed that the level of testosterone decreased and levels of LH and FSH increased significantly in varicocele control animals compared with healthy controls. َAlso, administration of linden extract has prevented hormonal changes and has significantly improved the sex hormones level and histological index in varicocele rats.Conclusion: The linden extract acts as a potent antioxidant against varicocele-induced damage in rats. Manuscript profile -
Open Access Article
225 - The effect of intraperitoneal injection of hydroalcoholic extract of flaxseed on biochemical, hematological and liver enzymes in rats
Atefeh PayezBackground: Medicinal plants have a wide range of applications in various fields, especially in the control of microbial infections, but the discussion of their possible toxicity has caused great concern in the use of these substances in various fields of industry and m MoreBackground: Medicinal plants have a wide range of applications in various fields, especially in the control of microbial infections, but the discussion of their possible toxicity has caused great concern in the use of these substances in various fields of industry and medicine. This study was performed to clarify some of these ambiguities and to investigate the effect of intraperitoneal injection of flaxseed extract on biochemical, hematological, and hepatic factors in rats.Materials and Methods: In this experimental study, 15 female spiral rats were randomly divided into 5 groups. The first group was the sham group, the second group was the control group, and the third to fifth groups as experimental groups with concentrations of 200, 400, and 600 mg/ml of flaxseed extract were treated, respectively. The mice were treated for 10 days, then on the eleventh day the mice were anesthetized with ether and blood samples were taken from their hearts. Then biochemical parameters, blood, and lactate dehydrogenase, and plasma levels of liver enzymes were evaluated.Results: The results of this study did not show much change in biochemical factors except cholesterol and triglycerides which showed a significant decrease in the extract-treated groups. Blood factors did not show significant changes but increased in high concentrations of liver enzymes.Conclusion: Intraperitoneal injection of flaxseed extract has no effect on blood factors and many biochemical factors in mice, but high concentrations of the extract can affect liver enzymes. Manuscript profile -
Open Access Article
226 - The Effect of 8 Week of Resistance Training with Licorice and Boldenone Extract on Sperm Cells, Sertoli and Leydig Testicular Tissue of Male Rats
Abdolali Banaeifar Mahnaz Shahrokhian Kermani Sajad Arshadi Bahram AbediInroduction & Objective: Anabolic-androgenic steroids popular among athletes have many beneficial and harmful effects on the body. Therefore, the aim of this study was to explain the effect of 8 hours of moderate intensity resistance training with licorice and Bolde MoreInroduction & Objective: Anabolic-androgenic steroids popular among athletes have many beneficial and harmful effects on the body. Therefore, the aim of this study was to explain the effect of 8 hours of moderate intensity resistance training with licorice and Boldenone extract on sperm cells, Sertoli and Leydig testicular tissue of male rats. Materials and Methods: For the present experimental study, 40 8-week-old male rats weighing 20-220 g were selected and divided into 8 groups of 5, including healthy control, resistance training, and bulldon, Licorice, Boldenone + Licorice, Boldenone, Resistance Training, resistance training + licorice and resistance training + Boldenone + licorice were divided. Then, the resistance training groups performed moderate-intensity training 8 times a week and three times a week, the Boldenone groups received 5 (mg / kg) Boldenone once a week, and the licorice groups received weekly exercise. They received 500 (mg / kg) licorice three times. 48 hours after the last training session, rats were anesthetized by injection of ketamine (70 mg / kg) and xylarine (10 mg / kg) and after incision in the anterior part of the abdominal wall, testicular tissue was removed and tested Stored in refrigerator-80. Finally Data were analyzed using three-way ANOVA and Tukey post hoc tests. Results: The results showed that there was a significant difference between the means of spermatoid, sertoli and testicular tissue of male rats in different groups. Conclusion: According to the results of the present study and the effect of exercise and licorice, it is recommended that athletes use these exercises and licorice in consultation with a physician. Manuscript profile -
Open Access Article
227 - Histophysiological and histochemical study of the intestine in golden hamster (Mesocricetus auratus) with emphasis on Goblet cells
Fatemeh Pourvali seyed Mehdi Banan. Khojasteh Masood DelashoobInroduction & Objective: The intestines are an important organ in the body of rodents due to the digestion and absorption of food and water, digestive digestion, microbial activity, production of immunoglobulin. The aim of this study was to investigate the histology MoreInroduction & Objective: The intestines are an important organ in the body of rodents due to the digestion and absorption of food and water, digestive digestion, microbial activity, production of immunoglobulin. The aim of this study was to investigate the histology of the golden hamster intestine and its goblet cells using histological and histochemical techniques.Material and Methods: Five adult and healthy male golden hamsters with an average weight of 120 g were prepared from experimental animal. After sampling from different parts of the intestine and preparing tissue sections, tissue samples were stained by Hematoxylin-Eosin, Periodic Acid Schiff and Alcian Blue methods and then studied by light microscope and the necessary micrographs for Histological studies were prepared .Results:In histopathological study, small and large intestine have 4 layers of mucosa, submucosa, muscular layer and serosa. The intestinal epithelium was consisted of simple columnar cells with a basal oval nucleus, that Mucus secreting goblet cells were seen among the columnar cells which both acidic and neutral mucus were secreted by these cells. It should be noted that the number of goblet cells increased from duodenum to colon and it was positive in PAS and Alcian Blue.Conclusion: The results show that the anatomical and histological structure of the golden hamster intestine, despite minor differences, is very similar to that other rodents. Manuscript profile -
Open Access Article
228 - Evaluation of the cytotoxic effect of chamomile ethanol extract on Hela and MCF-7 cancer cell lines
Morteza Maleky Forouzan Ghasemian RodsariBackground & Aims: Cancer remains a leading cause of mortality worldwide and breast (MCF-7) and cervical (Hela) cancers rank among the most prevalent malignancies in women. The search for natural compounds with extended shelf life and reduced side effects has prompt MoreBackground & Aims: Cancer remains a leading cause of mortality worldwide and breast (MCF-7) and cervical (Hela) cancers rank among the most prevalent malignancies in women. The search for natural compounds with extended shelf life and reduced side effects has prompted plants for cancer investigations into the potential use of medicinal pretreatment. This study aimed to evaluate the impact of chamomile ethanol extract on the viability of MCF-7 and Hela cancer cell lines using the methyl thiazole tetrazolium test.Materials & Methods: The cell lines were exposed to chamomile ethanol extract for 48 hours, to varying concentrations of chamomile the results were analyzed based on the inhibitory concentration (IC50) for cell growth.Results: The IC50 value was calculated as 1420 μg/ml for the Hela cell line and 1760 μg/ml for MCF-7 cancer cells. Chamomile ethanolic extract decreased cell survival in a dose-dependent manner in both cell lines and the growth inhibition percentage of both cell lines increased with increasing extract concentration. Notably, the findings revealed that MCF-7 cancer cells are more resistant to treatment with chamomile extract than cervical cell lines.Conclusion: Moreover, the chamomile extract demonstrated a more candidate anticancer effect on Hela cancer than on the MCF-7 cancer cell line. Manuscript profile -
Open Access Article
229 - study the effect of Ziziphora Extract on Claudin1 Gene Expression in Cancerous Cell line AGS.
Zahra Deilami Khiabani Sara NayyeriBackground & Aims: Claudins are the main structural and functional proteins of tight junctions in epithelial cells. The altered expression patterns of differ­ent claudin members have been demonstrated in a variety of diseases, particularly in cancers. It h MoreBackground & Aims: Claudins are the main structural and functional proteins of tight junctions in epithelial cells. The altered expression patterns of differ­ent claudin members have been demonstrated in a variety of diseases, particularly in cancers. It has been reported that claudin 1 is overexpressed 22-fold in gastric adenocarcinoma. Considering the least side effect of herbal extracts, in this study we have evaluated claudin-1 gene expression in AGS cells treated with ziziphora extract.Materials and Methods: The AGS cells were incubated 37°C containing 5% CO2 with 85% humidity DMEM with 10% FBS . The cells were treated with concentrations of 800, 1200, 2000 μg /ml of ziziphora for 48 and 72 hours. Extraction of RNA, synthesis of cDNA has been done using kit. The study of claudin-1 gene expression was performed by Real time PCR and also GAPDH gene was used as the internal control. Data analysis was performed with 2 - ΔΔCT and statistically analyzed by T-Test .Results: The results of Real time PCR data have shown in 48 hours treatment, reduction of 7 and 2.3 fold with concentrations of 800 and 1200 μg /ml of ziziphora respectively and in 72 hours treatment, reduction of 5.8 and 10 fold have seen in concentrations of 800 and 1200μg /ml of ziziphora, respectively and there was no significant change in concentration of 2000μg / ml in both treatments.Conclusion: Ziziphora extract in 1200 μg /ml concentration, reduced the expression of claudin-1 remarkably. Claudin-1 may become therapeutic targets for cancer treatment and ziziphora as a herbal extract decreased the expression rate of claudin1significantly, in lower concentrations treatment. Manuscript profile -
Open Access Article
230 - Evaluation of the Use of Artificial Intelligence (AI) for Low & High-Grade OSCC Diagnosis from Normal Mucosa
Mehran Arshadi Fard Nader Kalbasi -
Open Access Article
231 - Comparison of blood cell factors in patients with pulp calcification
Fatemeh Mehdikhani Nasim Jafari Pozve Seyed Sasan Aryanezhad -
Open Access Article
232 - Sports and social reflections from the perspective of "Marcel Mouss"
Kamal JavanmardObjective: What follows is an overview of the views and ideas of Marcel Mouss, the conqueror of the new land of sports sociology.A land where man is called the product of his body and it is thought that all techniques of the body are the result of the cultural context a MoreObjective: What follows is an overview of the views and ideas of Marcel Mouss, the conqueror of the new land of sports sociology.A land where man is called the product of his body and it is thought that all techniques of the body are the result of the cultural context and the process of socialization, and physical activitys are closely related to culture and social system."Mars Mouss" is the conqueror of a land that heralds the entry of social science into the field of physical activity as well as games and sporting events, thus laying the foundation for the sociology of sport.Methodology: The research method of this study is based on the nature of the subject of documents, and accordingly, the library technique was used to collect information.Results: In this article, first a brief look at the life and works of this French sociologist and then his theoretical application in the field of games and sports is explained and the foundations of his thoughts in the field of emerging science of sports sociology are examined and then the foundation is explained. His ideas about total social realities, including games and sports, are theoretically emphasized by focusing on the article "Techniques crops" and focus on human nature and the nature of physical techniques, as well as human emotions, all of which have a cultural flavor and a common sociological element. He follows the name "habitus", and finally analyzes the games using the" Potlatch" Customs which "Marcel Mouss" borrowed from the natives of the East Coast, and claims that according to this Customs, the primitive tribes have human motivation and purpose.Conclusion: The game is not just about financial gain, but also non-economic goals, including strengthening relationships and promoting social status. Manuscript profile -
Open Access Article
233 - Factors Accelerating Students' Participation in Physical Activities of Schools in Iran
Farahnaz Shams Shahram AroufzadObjective: The purpose of this article was to determine the consequences of student participation in sports activities in Iranian schools.Methodology: The researcher collected information through in-depth interviews using purposive sampling method and snowball sampling MoreObjective: The purpose of this article was to determine the consequences of student participation in sports activities in Iranian schools.Methodology: The researcher collected information through in-depth interviews using purposive sampling method and snowball sampling technique. Then, the data obtained from interviews, articles, physical education instructions of education, books and clips related to the triangulation technique through method and data, are collected and theorized data method with the method of Charms approach, coding and analysis and Was analyzed.Results: The result of grouping the codes showed one main component and four sub-components. The main component included accelerators and sub-components such as cooperation with stakeholders, financial resources, support and incentive resources, political context.Conclusion: According to these accelerators, it can be acknowledged that these factors accelerate the process of student participation in school physical activity; This research can be used as a tool to analyze students' participation in physical activities in Iranian schools.Also, considering the importance of the role of valuation in government policies on the work of physical education teachers, it is therefore suggested that extracurricular trustees in the field of sports, motivating physical education teachers and school principals evaluate the activities of these loved ones at school level. Provide.Accelerators (cooperation with stakeholders, financial resources, supportive-incentive resources and political context) have affected both the process of sports participation and the consequences of sports participation. Therefore, it can be said that value orientation, health promotion policy, policy of paying attention to students 'age, strategic view of participation are among the sub-components affecting the political context, which should be at the top of the importance of paying attention to students' age. Because they are vulnerable and at the same time effective and future-making of society.The results of this study can help the organizations in charge of sports in the country to deal properly with the participation of students in the physical activities of Iranian schools. Also, conducting this research while creating awareness of the current situation for optimal planning and review of accelerators, which refers to the analysis, recognition and scrutiny of the entire system of student participation in physical activities and determining the factors affecting participation, can have benefits such as the possibility of participation. More in school physical activities, diversity in school physical activities, attention to the interests and needs of students, creating an informal and intimate atmosphere, revitalizing the vitality and freshness in students and better identifying sports talents. Manuscript profile -
Open Access Article
234 - A Soft Switching Boost Converter with an Active Coupled Inductor Snubber Circuit
Hadi Faezi Majid Zamani Mohammad Ali LatifzadehIn this paper, a new soft switching boost converter is presented. A lossless active snubber circuit including an auxiliary switch, three diodes, a capacitor and a coupled-inductor provides soft switching conditions for the main switch and the output diode, so that the m MoreIn this paper, a new soft switching boost converter is presented. A lossless active snubber circuit including an auxiliary switch, three diodes, a capacitor and a coupled-inductor provides soft switching conditions for the main switch and the output diode, so that the main switch and the output diode operate under ZCS and ZVS conditions, respectively. They turn on and off under the ZCS condition. The operation of the snubber circuit is associated with low current stress on the main switch and low current and voltage stress on the output diode. The proposed converter is able to maintain the smooth switching condition in a wide range of output load and input voltage variations. Working principles, steady state analysis and design procedure of this converter are discussed in detail. Also, to confirm the theoretical results, a laboratory sample is made and tested. It should be noted that, The laboratory results confirm the theoretical results comprehensively. Manuscript profile -
Open Access Article
235 - The Charging Circuit of the Energy Storage System of the Multi-Input Converter with High Gain (Design, Simulation and Laboratory Investigation)
Donya Taheri Ghazanfar Shahgholian Mohammad Mehdi MirtalaeiIn this article, a multi-input non-isolated converter topology with high gain is proposed for clean energy applications that require an energy storage system. The techniques of voltage multiplier cell and coupling inductor have been used to design the circuit, and by co MoreIn this article, a multi-input non-isolated converter topology with high gain is proposed for clean energy applications that require an energy storage system. The techniques of voltage multiplier cell and coupling inductor have been used to design the circuit, and by combining them, it is possible to use switches with low voltage stress and as a result, low conductivity. The charging performance of the energy storage system is explained and the structure and performance of the proposed converter are investigated for the design of a non-isolated multi-input converter with high voltage gain. The precise design method for the correct operation of the converter is presented and the simulation results of the converter performance are shown. Finally, in order to verify the accuracy of the results obtained from the simulation of the proposed converter, a laboratory sample has been made and a comparison has been made between the results. Manuscript profile -
Open Access Article
236 - Analysis of Celestial Traveling and Sightseeing in Masnawi
Shahriar HassanZadehMaulana's internal circumstances, like the rhetoric of his words and poetry, are full of miracle and charm; so as ascends him to the height of brevity and magic of words in the rank of speech; and with its mental seethings draws him towards the glorious waves of the Mat MoreMaulana's internal circumstances, like the rhetoric of his words and poetry, are full of miracle and charm; so as ascends him to the height of brevity and magic of words in the rank of speech; and with its mental seethings draws him towards the glorious waves of the Mathnawi and he himself is charmed in the appeal of the council of his words. No doubt, journey is one of the most influential discussions in the depth of Maulana's speculations in his noetic culture and was of sensational items in the sociological researches , either customs and science in the foundations of thoughts which appeals the wise and great thinkers' minds. Maulana who is not an exception in this category, has dealt with the itinerary manner, either extrovertly or introvertly in the Mathnawi and has expounded its mystical ranks in the internal and ascersion journey. He also showed his skill in the dignity of spiritual wayfarers of the credo. A part of his mystic traveling and sightseeing is formed in the abstract heaven and poses the ascentation of prophet Mohammad ( p. b. u. H. ) which includes two types of journey: first, specific ascentation which belongs to the prophet and Divine messengers and second, general ascentation which subsumes the spiritual journey of God's aminitrators. Manuscript profile -
Open Access Article
237 - A Comparative Study of the Soul from the Perspective of Hassanzadeh Amoli and Freud
ashraf mikaeili Sadegh SalehiIn psychology, self-knowledge and its levels play a fundamental role in human cognition. On the other hand, in many moral theories, psychology is the basis for the formation of moral virtues. Since the soul in the theories of Islamic philosophical ethics has similaritie MoreIn psychology, self-knowledge and its levels play a fundamental role in human cognition. On the other hand, in many moral theories, psychology is the basis for the formation of moral virtues. Since the soul in the theories of Islamic philosophical ethics has similarities with personality and psychology in the theories of psychology, a comparative study can be made between the views of Hassanzadeh Amoli and Freud. One of the most important issues in recognizing man and his personality is the discussion of the soul and related theories, and it can be said that what unifies the scattered studies of psychology and gives them a clear meaning and concept, the interpretation of this finding Studies in the shadow of the theory of the soul is coherent that can justify and explain human behavior in all its dimensions. Therefore, in this research, an attempt has been made to comparatively examine the soul from the perspective of Hassanzadeh Amoli and Freud through the method of content analysis. According to Hassanzadeh Amoli’s point of view, soul is an essence that is indefinable due to its unlimited scope of existence. The human soul will be a species under sex, not a person under species; But from Freud's point of view, the concepts of "he", "I" and "I am superior" are both different types of souls and occur at different stages of a person's development Manuscript profile -
Open Access Article
238 - A New Numerical Study Method of Thermal Stress Distribution and Tortuosity Effectiveness in an Anode Porous Electrode for a Planar Solid Oxide Fuel Cell
I.E Fahs M Ghasemi -
Open Access Article
239 - Analytical and Numerical Investigation of Energy Absorption in Graded Aluminum Open Cell Foam under Low Velocity Impact Loading
S Davari S. A Galehdari A AtrianGiven the significance of energy absorption in various industries, light shock absorbers such as structures made of metal foam have been considered. In this study, analytical equation of plateau stress is presented for an open cell foam based on the Gibson-Ashby model, MoreGiven the significance of energy absorption in various industries, light shock absorbers such as structures made of metal foam have been considered. In this study, analytical equation of plateau stress is presented for an open cell foam based on the Gibson-Ashby model, which follows elastic perfectly plastic behavior. For comparison of acquired analytical equations, the problem for a cell and then for three cells that make up an aluminum open cell foam is simulated in ABAQUS/CAE. Using the stress strain diagram, plateau stress and densification strain equations, the specific energy absorbed of the open cell metal foam is extracted. The capacity of absorb energy for an aluminum open cell foam with three cell is obtained once using analytical equations and again by using numerical simulation in ABAQUS/CAE. Numerical results retain an acceptable accordance with analytical equations with less than 3% occurred error for absorbed energy. To ensure the accuracy of numerical simulation, the results of simulating are compared with the results of the simulation of the same foam in a reference whose accuracy is verified by the experiment. Based on the results, the effective cross-sectional area of the foam with Gibson-Ashby cell does not follow the cross-sectional that is used for the calculation of plateau stress in adsorbent structures. Then tow equations are extracted to calculate the effective cross-sectional area and the transfer force. Applying sequential quadratic programming method (SQP) and genetic algorithm (GA), to design a graded metal foam with high specific Energy absorption. Manuscript profile -
Open Access Article
240 - Cell Deformation Modeling Under External Force Using Artificial Neural Network
M.T Ahmadian G.R Vossoughi A.A Abbasi P Raeissi -
Open Access Article
241 - Seismic Analysis of Rectangular Concrete Tanks by Considering Fluid and Tank Interaction
M Yazdanian S.V Razavi M Mashal -
Open Access Article
242 - Effects of Marjoram, wild mint and Summer savory essential oils on mycellial growth of Botrytis cinerea
Ehsan Hasanvand seddiqe mohammadi Tahereh BasirniaThe use of antifungal compounds such as essential oils for the preservation of natural fruits during the storage period has dramatically been rising. In this study, the individual essential oils of Marjoram (Origamum marjorana), wild mint (Mentha longifolia) and Summer MoreThe use of antifungal compounds such as essential oils for the preservation of natural fruits during the storage period has dramatically been rising. In this study, the individual essential oils of Marjoram (Origamum marjorana), wild mint (Mentha longifolia) and Summer savory (Satureja khuzistanica) were employed for the control of corruption of fruits during the storage period. In this study, the antifungal activity of essential oils was investigated on growth a specie of plant pathogenic fungus Botrytis cinerea on PDA medium and fruit tissues. Antifungal activities on PDA medium were measured by disk diffusion and volatile essential oil methods. To evaluate the effects of the essential oils on fungal growth in fruit tissue, the Kiwi were inoculated with 30 µl of spore suspension (106 spore/ml), and then fruits were sprayed with 4 and 20 µl/ml of the essential oils. Seven days after inoculation, fruits were evaluated in terms of pollution. To calculate the percentage of infected fruit was divided into eight parts and the number of infected fruit fungus pathogen contamination in 12.5% multiplication and percentages were calculated. Data were analyzed as a completely randomized design with three replications. Essential oils have showed significant inhibitory effect on fungus growth. The results showed that most inhibition of growth in a paper disk method was in order for fungus B. cinerea related to the essential oil of Summer savory 56.54 percent respectively and volatile essential oil methods was related to the essential oil of Summer savory was 55.97 percent respectively. The results inoculated of the fruit tissue with a spore suspension B. cinerea showed that respectively treatment (20µl/ml) of Marjoram (with 35.42% of disease) had the inhibitoriest effect against the pathogen. Manuscript profile -
Open Access Article
243 - A preliminary study on the biology of Epiblema aquana (Lepidoptera: Tortricidae) in rose gardens of Kashan, Iran
Mohammad Reza NematollahiDamask rose (Rosa damascena Mill.), a plant growing in low water area of Kashan (Iran), has economic importance. One of the pests of the plant is Epiblema aquana (Hubner) [=Notocelia raborana Den. & Sciff.]from Lepidoptera order and Tortricidaefamily. During 2000-20 MoreDamask rose (Rosa damascena Mill.), a plant growing in low water area of Kashan (Iran), has economic importance. One of the pests of the plant is Epiblema aquana (Hubner) [=Notocelia raborana Den. & Sciff.]from Lepidoptera order and Tortricidaefamily. During 2000-2001 some aspects of pest morphology and biology were studied in rose gardens of Kashan region. By inspecting rose gardens in different regions of Isfahan province (Iran), host range of the pest was studied by inspecting different plants inside and margins of the rose gardens and infected regions were recorded. Results showed that the larvae start their feeding from early May. After formation of flower buds, they make a feeding nest, through spinning threads between buds and the nearest leaves. Larval feeding leads to destruction of small buds and damage to larger buds. Adults appeared from late June to early August and females laid the eggs in clusters, under leaves. In addition to damask rose, the pest could feed on other roses and also on fruit trees in the margins of rose gardens. The pest was distributed in different rose gardens of Kashan and Ghamsar regions. The highest density, however, belongs to Barzok region, which has the highest cultivation area of damask rose in the province. Manuscript profile -
Open Access Article
244 - Effect of extracellular fluid of Trichoderma and Talaromyces flavus isolates against Gaeumannomyces graminis var. tritici causal agent of wheat take-all disease
Leila Ghanbari Sedigheh Mohammadi Laleh NaraghiWheat take-all, caused by Gaemannomyces graminis var. tritici,has been observed in recent years in different areas of Iran. In this study, in order to investigate the possibility of biological control of pathogen, seven isolates Trichoderma include T. harzianum S, T. ha MoreWheat take-all, caused by Gaemannomyces graminis var. tritici,has been observed in recent years in different areas of Iran. In this study, in order to investigate the possibility of biological control of pathogen, seven isolates Trichoderma include T. harzianum S, T. harzianum A, T. harzianum M, T. koningi, T. longibrachiatum and T. virens and four isolates of Talaromyces include Talaromyces flavus 134, Talaromyces flavus 136, Talaromyces flavus 75 and Talaromyces flavus 60 used against the pathogen by extracellular fluid method in vitro condition. The experiment was arranged as randomized complete design with 3 replication. The effect of extracellular fluid of antagonistic isolates on mycelia growth of Ggt indicated that the extracellular fluid of Talaromyces flavus 136، T. harzianumand T. harzianum S isolates the rate of 5 ml after 72 hours of rate (41/51, 40/88 and 37/73 %) and T. longibrachiatum isolate at rate of 10 ml at two times of measurement (52/83 and 52/38%) had the most inhibition effect on the growth of pathogen. This study has been the first study related to biological control of wheat take-all by T. flavus. Manuscript profile -
Open Access Article
245 - A study on biology of Parmacella ibera and its damage assessment in citrus orchards of Mazandaran province
Mohammad Fazel Halajisani Elham AhmadiThe slug Parmacella ibera Eichw is one of the most important pests in citrus orchards and nurseries of Mazandaran province. Investigation on the biology of P. ibera was carried out on Thompson navel nurseries in Ramsar during 2006-2007. This species has one generation i MoreThe slug Parmacella ibera Eichw is one of the most important pests in citrus orchards and nurseries of Mazandaran province. Investigation on the biology of P. ibera was carried out on Thompson navel nurseries in Ramsar during 2006-2007. This species has one generation in a year and slugs were coupling in late March and oviposit in the middle of April. It took almost 22 days from coupling to oviposition. Average egg cluster was 52. Mean duration of incubation period was 28 days. The hatchability of eggs was 65 percent. A mean number of 50 newly hatched slugs were counted per adult. For damage evaluation of P. ibera, slugs were released in four (1,5,10,15) density on the single branch of a citrus tree of age 12-15 years in six replications (slug infestation) and compared with the control treatment. Citrus leaves damaged by slug before and after slug releasing were counted at seven day intervals. The citrus fruits available were counted and till the end of sampling their weights were compared with control treatment. The results showed that the mean numbers of leaves and fruits at different treatments for variety and population abundance were statistically meaningful (P≤0.05). The relation between density and damage was found linear and correlation between number of damaged leaves and fruits and total percentage of damages in Thompson navel orange and Unshui mandarin with population abundance of slug were found statistically meaningful. The mean of damages in relation to the slug densities (1, 5, 10, 15) were significant (P≤0.05) for Thompson navel orange and Unshui mandarin respectively. The result indicates that Unshui mandarin variety is more damaged by the slug feeding. Manuscript profile -
Open Access Article
246 - The effect of infection of Arceuthobium oxycedri on Juniperus excels species in North West forests of Iran
Mir Mozaffar Fallahchaei Yousef Torabian Majid Maani Farzaneh AhmadiOne of the most important destruction reasons of Juniperus aged and Long Lived trees in Jaysh Abad sits of Tarom township is a semi-parasitic plant from Dwarf Mistletoes group of viscaceae family. Biological study done in Jaysh Abad area of Tarom Township and other Juni MoreOne of the most important destruction reasons of Juniperus aged and Long Lived trees in Jaysh Abad sits of Tarom township is a semi-parasitic plant from Dwarf Mistletoes group of viscaceae family. Biological study done in Jaysh Abad area of Tarom Township and other Juniperus sits in Zanjan province of Iran revealed that this semi-parasitic plant is Arceuthobium oxycedri. For determining the infection percent, intensity, quality and quantity on the host species half hectare sample pieces were randomly selected in 4 geographical directions. The results of this study showed that Dwarf Mistletoes mostly influences trees with bigger crown size, crown area, height and diameter breast height. Also result showed that Juniperus trees in south directions are more infected in comparison with other directions. Manuscript profile -
Open Access Article
247 - Investigation of Salinity and Moisture on the Germination of Weed Seeds Mallow,Barnyard grass and Johnson grass in Terms of Deterioration of Seeds
Ghodratolah Fatahi Eynolah Hesami Nima ArdalanIn order to evaluate the effects of seed deterioration on capability of seed germination and seedling of three weeds-Malva neglecta L., Echinochloa crus-galli L.and Sorghum halepense L.-under saline stress conditions, an experiment was conducted at university of Ramin i MoreIn order to evaluate the effects of seed deterioration on capability of seed germination and seedling of three weeds-Malva neglecta L., Echinochloa crus-galli L.and Sorghum halepense L.-under saline stress conditions, an experiment was conducted at university of Ramin in Khuzesatan. The arrangement was factrorial in form of a completely randomized design with 4 replications (RCD) in 2012. In this experiment, The first factor was weed seeds at 3 levels (Malva neglecta, Echinochloa crus-galli and Sorghum halepense), the second factor was deterioration treatments at 4 levels (0, 3, 5 and 7 days), and the third factor was salinity (0,4,8 and 12dSm-1), and the forth factor was moisture stress at 3 levels (saturation field capacity(FC) and 50%FC). The results of experiment showed that seed deterioration and saline stress reduce all measured characteristics including time, speed, uniformity, persentage and emergence index, germination percentage, radicle length, plumul length, vigos index, and seedling dry weight. A significant difference was observed at %1 level. Saline stress resulted in reduction of determined characters in the experiment. Whwrase in Wherase in Malva niglecta moisture Stress of 50% FC, FC and saturation reduced percentage of germination, in barnyard grass and johnsongrass the highest germination percentage was observed in saturation tseated seeds and the least percentage of emergences was observed in %50 FC treated seeds. Our results indicated that seed deterioration increased the effect of salinity on weed seedling establishment and seed germination. Manuscript profile -
Open Access Article
248 - Pseudo-Random Number Generation Based on Cellular Automata AndLongton Ants
SeyedMorteza Hosseini Hossein Karimi Majid Vafaei JahanCellular automata with evolutionary and complex behaviors are used in several applications such asgenerating random numbers, cryptography and optimization problems solving. In random numbersgeneration, this structure cannot produce long sequence of random numbers. For i MoreCellular automata with evolutionary and complex behaviors are used in several applications such asgenerating random numbers, cryptography and optimization problems solving. In random numbersgeneration, this structure cannot produce long sequence of random numbers. For increasing thesequence of numbers, heterogeneous cellular automata with variable rules or combination of severalautomata may be used. In this paper combined heterogeneous cellular automata with contribution oflangton's ant as random number generator is presented. Langton's ant is a simple discrete dynamicalsystem, with a surprisingly complex behavior.Cellular automata are considered as generator of randomnumber and langton's ant is considered as stimuli of cellular automata and determiner of automata rule.Experimental results show that, in spite of our expectation, combination of langton's ant and cellularautomata does not have chaos behavior but illustrates pseudo-random behaviorwhich it results incycles of very long period lengths with limited number of cells such that a period length 2 isobtained by n cells. In addition to independence of initial core (initial value), it has been also provedthat generated numbers are independent of each other. Accordingly, some tests of random numbergenerators such as entropy, overlapping, minimum distance and Diehard(set of 17 triple test) havebeen performed and all of them have been successfully passed Manuscript profile -
Open Access Article
249 - پیوند و تنیدگی اندیشههای ناسوتی و لاهوتی ایرانیان در «عید نوروز»
حجت اله غ منیری -
Open Access Article
250 - Effects of lifestyle activity modification on insulin resistance and pancreatic β-cells function in obese men with insulin resistance
Mohadeseh Nematollahzadeh mahani Jalil Ghasemian poor -
Open Access Article
251 - Evaluating the effect of low-intensity eccentric resistance training combined with blood flow restriction on the systematic and genetic indices affecting the activation and proliferation of satellite cells in young non-athlete men
Azam Mousavian Abbas Ali Gaeni Reza Nuri Mohammad Reza Kordi -
Open Access Article
252 - Effects of concurrent training on insulin resistance and pancreatic β-cells function in obese men
Ahmad Ahmadlu Afsaneh Khazari Zahra Momen nasab -
Open Access Article
253 - Regular aerobic training improves insulin resistance but not pancreatic β-cells function in female patients with type 2 diabetes
Mohsen Omidi Mehrzad Moghadasi -
Open Access Article
254 - Providing a hybrid strategy based on the theory of turbulence and price acceleration in the Iranian stock market
Rohollah Hamidi Ali Saeedi Mohammad Khodaei Valazaghard Mehdi Naghavi -
Open Access Article
255 - Determining the appropriate weights of criteria in multi-criteria decision-making using cooperative game: A case study of bank
Seyed Hadi Mousavi-Nasab Jalal Safari Ashkan Hafezalkotob -
Open Access Article
256 - Identification of the egg parasitoids of green pistachio stink bug, and the effect of diet on adult longevity of the two parasitoids, Ooencyrtus pityocampae (Mercet) and Trissolcus agriope (Kozlov and Lê)
M. Mohammadpour M. Ziaaddini M. A. Jalali H. Hashemirad H. LotfalizadehThe green bug, Brachynema signatum Jakovlev (Hem.:Pentatomidae) is one of the most important active pentatomids on pistachio trees, that smudge the nuts with feeding on those that are premature. In this research, the parasitoid wasps of the pistachio green stink bug wer MoreThe green bug, Brachynema signatum Jakovlev (Hem.:Pentatomidae) is one of the most important active pentatomids on pistachio trees, that smudge the nuts with feeding on those that are premature. In this research, the parasitoid wasps of the pistachio green stink bug were collected and identified around the city of Rafsanjan using egg traps. Also, the effect of diet on longevity of two egg parasitoids, Ooencyrtus pityocampae (Hym.:Encyrtidae) and Trissolcus agriope (Hym.: Scelionidae) were determined. Treatments were honey, 10% honey-water, distilled water, B. signatum egg and control (without water and food). Five parasitoids, including Trissolcus agriope (Kozlov and Lê), T. dryope (Kozlov and Lê), T. mitsukurii Ashmead and Psix sp. of the Scelonidae and Ooencyrtus pityocampae (Mercet) and O. telenomicida (Vassiliev)of the Encyrtidae were collected and identified. The average longevity of the O. pityocampae in females were 45.15, 38.5, 9.30, 19.81and 8.23 days and in males were 39.15, 37.5, 7.80, 9.09 and 4.19days, respectively. This period for the T. agriope species in females were 30.93, 30.03, 13.25and 7.28 days and in males were 26.40, 22.38, 8.37 and 5.42days, respectively. The results showed that feeding has an effective role on increasing the longevity of the parasitoids and also a significant difference observed between the average longevity of two mentioned parasitoids. The longevity of female O. pityocampae wasps increased to 45.15±1.37 days in the treatment of honey, but water hadn't effect on the longevity of this species. Also the longevity of this species was reduced to 9.09±0.74 days in the presence of host eggs. The average longevity of Trissolcus parasitoid increased to 30.93±0.79 days in treatment with honey. Therefore, kind of diet can have an important role on increment of parasitoid wasps' longevity. Manuscript profile -
Open Access Article
257 - Effect of active composite coating enriched with Echinacea purpurea L. Moench extract on the shelf life of Oncorhynchuus mykiss fillet during cold storage
mojtaba ghorbani dariush khademi shurmasti Yasaman Fahim DezhbanTo investigate the effect of active composite coating carboxymethyl cellulose-based on the shelf life of rainbow trout (Oncorhynchuus mykiss) fillet during refrigerator temperature storage, an experiment for 12 days with 5 treatments including uncoated (control), carbox MoreTo investigate the effect of active composite coating carboxymethyl cellulose-based on the shelf life of rainbow trout (Oncorhynchuus mykiss) fillet during refrigerator temperature storage, an experiment for 12 days with 5 treatments including uncoated (control), carboxymethyl cellulose 1%, carboxymethyl cellulose-oleic acid 1%, carboxymethyl cellulose-oleic acid-Echinacea extract (0.5% or 1%) and 3 replications was carried out. Chemical (PV, TBARS, and TVN) and microbial (TVC and PTC) tests were performed on the fillets every 3 days. The results showed that oleic acid improved the protective effect of carboxymethyl cellulose coating. The antioxidant and antibacterial effect of Echinacea extract was concentration dependent. At the end of the storage period, the lowest values of PV (3.90±0.11 meq/kg), TBARS (1.24±0.27 mg MDA/kg), TVN (21.90±1.83 mg/100g), TVC (5.10±0.10 log cfu/g) and PTC (5.23±0.06 log cfu/g) were found in fillets containing active composite coating of carboxymethyl cellulose-oleic acid-1% Echinacea extract (P <0.05). Therefore, the composite coating of carboxymethyl cellulose-oleic acid-1% Echinacea extract can be used as an active packaging to maintain the quality and increase the shelf life of rainbow trout fillets during short-term storage at refrigerator temperature. Manuscript profile -
Open Access Article
258 - Effect of carboxymethyl cellulose-based nanocomposite coating on internal quality and eggshell morphology during storage at ambient temperature
ali akbar sharifi dariush khademi shurmastiIn order to investigate the effect of biodegradable nanocomposite edible coatings carboxymethylcellulose-based on the internal quality and morphology of the table eggshell surface an experimental with 120 eggs in a completely randomized design with 4 treatments and 3 re MoreIn order to investigate the effect of biodegradable nanocomposite edible coatings carboxymethylcellulose-based on the internal quality and morphology of the table eggshell surface an experimental with 120 eggs in a completely randomized design with 4 treatments and 3 replicates were performed. Treatments included uncoated eggs (control), eggs containing carboxymethylcellulose coating, eggs containing carboxymethylcellulose-oleic acid coating and eggs containing carboxymethylcellulose-oleic acid-nanoclay nanocomposite coating. Coating was done by immersion method and the eggs were stored at ambient temperature (25±1oc) for 5 weeks. Internal quality parameters were evaluated at the end of weeks 1, 3 and 5 and eggshell surface morphology at the beginning and end of the experimental period. The results showed that eggs containing nanocomposite coating at the end of storage period have the lowest percentage of weight loss and the lowest numerical value of thiobarbituric acid index (P <0.05) and the highest numerical value of albumen pH, the highest numerical values of yolk index and haugh units (P <0.05). In addition, the surface of the eggshell containing nanocomposite coating was more integrated and less porous and fractured than the control group. Therefore, the nanocomposite coating of carboxymethylcellulose-oleic acid-nanoclay can be used as a biocompatible packaging for storage eggs at ambient temperature for 5 weeks without adversely affecting the internal quality and eggshell. Manuscript profile -
Open Access Article
259 - Investigating the chemical and microbial parameters of spoilage and determining the shelf life of Cyprinus carpio fillet Under the influence of carboxymethyl cellulose coating containing Salvia officinalis extract
Moammad Esmaeili Yasaman Fahim DezhbanIn the present study, the effect of carboxymethyl cellulose oral active coating containing salvia officinalis extract on the quality and shelf life of common carp fillet during the storage period in the refrigerator (4±1℃) was investigated. Common carp fillets in MoreIn the present study, the effect of carboxymethyl cellulose oral active coating containing salvia officinalis extract on the quality and shelf life of common carp fillet during the storage period in the refrigerator (4±1℃) was investigated. Common carp fillets in five control groups were treated with carboxymethyl cellulose coating without extract and containing 0.5% and 1% sage extract and kept in refrigerator for 12 days, chemical (pH, TVN, PV, TBA) and microbial (Total and Psychrophilic bacterial load) indicators were investigated. The results of this research confirm the better performance of carboxymethyl cellulose coating containing 1% sage extract compared to other treatments; So that the chemical indices and amounts of total and Psychrophilic bacteria as microbial indices of quality control of had better results than other treatments until the end of the storage period and showed was able to provide acceptable quality by reducing the Total bacterial amount and the amount of Psychrophilic bacteria in the samples. According to the results of the evaluation chemical indicators affecting spoilage, the application of carboxymethyl cellulose coating containing 1% of sage extract can more effectively cause damage by controlling and reducing the oxidation of lipids than other treatments. Maintain the quality of common carp fillets during the storage period. Therefore, Salvia officinalis extract, having antioxidant and antimicrobial properties, as a natural biological preservative in combination with coating of carboxymethyl cellulose, can be used as a method to maintain the quality and increase the shelf life of common carp fillets during storage in the refrigerator. Manuscript profile -
Open Access Article
260 - Green synthesis of cellulose acetate/zinc oxide nanocomposite filter with plant extract and its application in water source pollution removal
Sohrab Hajmohammadi Dadkhoda Ghazanfari Enayatollah Sheikhhosseini Nahid Rastakhiz Hamideh AsadollahzadehWater resources are among the natural capitals of every country, therefore, the preservation of these natural resources is one of the important challenges of all countries. Excessive use of chemical and industrial materials has created many problems for these sources. T MoreWater resources are among the natural capitals of every country, therefore, the preservation of these natural resources is one of the important challenges of all countries. Excessive use of chemical and industrial materials has created many problems for these sources. Therefore, providing new methods to remove water pollutants is very important. The method of green synthesis of nanoparticles has attracted a lot of attention due to its features such as greater safety, compatibility with the environment, simplicity, and low cost. In this research work, the green synthesis of zinc oxide nanoparticles was carried out using the Daphne macronata plant and it was used in the preparation of a cellulose acetate/zinc oxide filter. The electron microscope image of the nano filter shows that the average diameter of nanofibers is about 40 nanometers and the average size of nanoparticles is about 47 nanometers. Also, the effect of this filter in removing methyl orange dye from water sources was investigated in different conditions of dye concentration, amount of adsorbent, and pH. The results showed that the cellulose acetate/zinc oxide nanocomposite filter is able to remove about 90% of methyl orange color in optimal conditions. Also, the results of investigating the antimicrobial effect of this structure on 4 samples of pathogenic bacteria, including Bacillus cereus and Staphylococcus epidermis, Salmonella, and Acinetobacter were carried out. The results showed that the largest diameter of the halo of non-growth is related to the pathogenic bacteria Bacillus cereus and Staphylococcus epidermis and is about 22 mm Manuscript profile -
Open Access Article
261 - The Mesoproterozoic – no “boring billion”
Uwe-M. Troppenz Sven Littkowski -
Open Access Article
262 - Use of Sawdust of Aspen Tree for the Removal of Chromium (VI) from Aqueous Solution
M.T. Hamed Mosavian I. Khazaei M. AliabadiAdsorption capacity of Cr (VI) onto sawdust of aspen tree and activated sawdust, was investigated in a batch system by considering the effects of various parameters like contact time, initial concentration, pH , temperature, agitation speed, absorbent dose and particle MoreAdsorption capacity of Cr (VI) onto sawdust of aspen tree and activated sawdust, was investigated in a batch system by considering the effects of various parameters like contact time, initial concentration, pH , temperature, agitation speed, absorbent dose and particle size. Cr (VI) removal is pH dependent and caused to be maximum at pH 2.0. The amounts of Cr(VI) adsorbed increased with increase in dose of both adsorbents and their contact time. Experimental results show that the low cost biosorbent was effective for the removal of pollutants from aqueous solution. The Langmuir, Freundlich and Temkin isotherm were used to describe the adsorption equilibrium studies of agrowaste. Freundlich isotherm shows better fit than Langmuir and Temkin isotherm in the temperature range studied. Manuscript profile -
Open Access Article
263 - Determination of the Geological Conditions During the Formation of Kaolinite and Bentonite Deposits in NW Alborz Mountains (Pirkoh-Deylaman) of Iran and the Study of Its Practical Properties for Use in the Porcelain Industry
Farzad Asadi Ali Darvishzadeh Ali MontezeriThe area under study is located in northern Iran at 36° 47’ latitude and 50° 12' longitude. It is 15 km from southeastern Deylaman. Petrological study of the kaolin mother rock (Eocene age) under a microscope shows that the rock is vitric tuff with a rhyol MoreThe area under study is located in northern Iran at 36° 47’ latitude and 50° 12' longitude. It is 15 km from southeastern Deylaman. Petrological study of the kaolin mother rock (Eocene age) under a microscope shows that the rock is vitric tuff with a rhyolitic combination containing falcated and embowed glass shards. The thickness of the layer is approximately 20 meters, formed unconformably on a layer of conglomerate with a thickness of approximately 400 meters. Because the shards have a falcated and embowed shape and the percentage of reworked material within them is low, the tuff can be considered a type of pyroclastic airfall. The results of the study prove that ash falling occurred in the water. The stratabound layers show syngenetic deposits to be the main factor in the formation of the clay, bound as a result of alterations. Manuscript profile -
Open Access Article
264 - Optimization of gel formulation containing CMC, HPMC, and PVA enhanced cosmetic, hygiene, and pharmaceutical applications using central composite design (CCD)
Rezvan Ahmadi pour Farzaneh EbrahimzadehIn this study, the characteristics of gels produced from polymers including carboxymethyl cellulose (CMC), hydroxypropyl methylcellulose (HPMC), and polyvinyl alcohol (PVA) were investigated as functions of transparency preservation, pH, and viscosity retention over a p MoreIn this study, the characteristics of gels produced from polymers including carboxymethyl cellulose (CMC), hydroxypropyl methylcellulose (HPMC), and polyvinyl alcohol (PVA) were investigated as functions of transparency preservation, pH, and viscosity retention over a period of 60 days. The investigation was conducted using Design Expert software and by employing a design of experiments based on a Central Composite Design (CCD) model. Changes in the weight ratio of the gel producer's implementation are considered the independent variable, while variations in pH, transparency, and viscosity changes of the produced gels over a 60-day period are recognized as the dependent variables. The variations in viscosity over the course of 60 days, at time intervals of 1, 7, 14, 28, and 60 days, for CMC, HPMC, and PVA individually, indicate that without the presence of a cross-linking agent, viscosity undergoes changes over time. Through a detailed analysis of the results obtained from 16 designed experiments, the optimal gel formulation, which ensures the preservation of structure, transparency, and pH within the neutral range, as well as the retention of viscosity over time, was predicted. This optimal formulation consists of a weight ratio of 9.68% CMC, 1.27% HPMC, and 4% PVA. Manuscript profile -
Open Access Article
265 - Independent Organization Model Based on Managers' Economic and Organizational Policies
Ali Karami Masoumali Salimian Mehran Mokhtari Ghorbanali Agha Ahmadi -
Open Access Article
266 - Designing Cell Production Arrangement Scenarios with the Approach of Artificial Neural Networks
Mahdi Ahmadipanah Kamyar Chalaki Roya Shakeri -
Open Access Article
267 - The Combination of Organizational Factors Affecting the Performance of Organizational Accelerators
Neda Hasanpuor Karam Sina Mojtaba Nasiri -
Open Access Article
268 - The Role Of Her Excellency Zeinab (SA) To Manage The Political- Religious Crisis In Captivity Period
Valiollah Naghipoorfar Mohammad Alizadeh Mohammad Javad Yavari sSartakhtiThis article with the aim to explain the role of Her Excellency Zeinab (SA) in Ashura movement and its crisis management, attempted to introduce a model of success for Muslim woman in the social and political arena. The biography case study of Her Excellency Zeinab (SA) MoreThis article with the aim to explain the role of Her Excellency Zeinab (SA) in Ashura movement and its crisis management, attempted to introduce a model of success for Muslim woman in the social and political arena. The biography case study of Her Excellency Zeinab (SA) as a woman from the prophet family during the captivity, because of the uniqueness of the event and the formation of new crisis in advancing the history of Shi'ism, along with a focusing on political and religious aspect is very important and could be a model for Muslim women. In this regard, referring to reliable sources, the required information was collected and by using descriptive-analytical way the extracted data was analyzed. Diagnosis of the crisis and its fields, underlying beliefs of crisis management, impressive characteristic features and managerial actions before, during, and after the crisis, were the four components of crisis management in the life of Her Excellency Zeinab (SA) that in this research were found and the result was that she could manage this crisis through the above four components, and turn it into an opportunity to expand Shiite political thought. Manuscript profile -
Open Access Article
269 - The Her Holiness Fatimah Zahra (PUH) Profile from Imam Khomeini Gnostic View
Akram Bohlouli Ali Yar HoseiniImam Khomeini discussed facts concerning existential mysteries of Excellency Fatimah Zahra that has been mentioned in religious and Gnostic literature. Imam Khomeini said: “Fatimah Zahra is the manifestation of all human accomplishments and in fact (Her Exce MoreImam Khomeini discussed facts concerning existential mysteries of Excellency Fatimah Zahra that has been mentioned in religious and Gnostic literature. Imam Khomeini said: “Fatimah Zahra is the manifestation of all human accomplishments and in fact (Her Excellency) is celestial existence that avatar in the world alike human.” Due to Her Excellency is a part of perfect comprehensive existence. While His Holiness ascend the natural and supernatural axis (His Holiness) not only surpass celestial existing but also go beyond the heaven so reached Allah. So Imam Khomeini as an Islamic scholar and deep philosopher and true gnostician has introduced Excellency Fatimah Zahra as history miracle and pride of existing world that human identity is manifested in her. Therefore Excellency Fatimah Zahra is the best sample of highest knowledge, virtue, science learning, education and simple living that can be introduced to the world. Manuscript profile -
Open Access Article
270 - Determination of Soil Aggregate Stability in Different Types and Amounts of Organic Matter in Khuzestan Plain, Iran
Mohiaddin Goosheh Mohammad Khayat -
Open Access Article
271 - Static Task Allocation in Distributed System Using Parallel Genetic Algorithm
Monire Taheri SarvetaminOver the past two decades, PC speeds have increased from a few instructions per second to several million instructions per second. The tremendous speed of today's networks as well as the increasing need for high-performance systems has made researchers interested in par MoreOver the past two decades, PC speeds have increased from a few instructions per second to several million instructions per second. The tremendous speed of today's networks as well as the increasing need for high-performance systems has made researchers interested in parallel and distributed computing. The rapid growth of distributed systems has led to a variety of problems. The most important problem that has been addressed by many researchers is the task allocation in such environments in order to obtain effective system efficiency. The task allocation problem is, except in a few specific cases, an NP-complete problem; so, heuristic methods are used to achieve suboptimal solutions in the desired time. Although different methods have been used in research, finding an effective and efficient method for this problem is still needed and desirable. This study used a parallel genetic algorithm to find the optimal solution for allocating a graph of tasks to the processors in a distributed system. The results showed that the proposed algorithm can provide optimal or near-optimal allocations for problems of different sizes. Also, the proposed method was able to solve problems of large and medium-size in a much faster time than traditional genetic algorithm with super linear speedup. Manuscript profile -
Open Access Article
272 - Investigation of the Strategic Thinking Role in Implementation of the EFQM Model through Organizational Learning within the Logistics Department of the Ministry of Energy and the Ministry’s Subsidiary Companies
Mehdi Etemadi Abdosamad KhodamiPresent research intends to look into the role of the strategic thinking in the implementation of the EFQM model through organizational learning within the logistics department of the Ministry of Energy as well as the Ministry’s subsidiary companies. To do this, f MorePresent research intends to look into the role of the strategic thinking in the implementation of the EFQM model through organizational learning within the logistics department of the Ministry of Energy as well as the Ministry’s subsidiary companies. To do this, four hypotheses formulation are presented and tested. The present research is based on the three variables: the strategic thinking as the independent variable, implementation of the EFQM model as the dependent variable and organizational learning as the mediator variable. The current research method in terms of applied objective, strategies and data collection is solidarity, quantitative, and survey questionnaire respectively. In this survey, statistical society includes all managers and field staff working for the Ministry of Energy and subsidiary companies in Iran with the number of 35324 persons, who are serving in 2015. Sampling in this study randomly with stratified kind and using Krejcie and Morgan table was designed for 384 people. Data analysis was conducted by applying the software such as SPSS statistical, Excel and Lisrel. The results of the proposed approach showed that strategic thinking and organizational learning both have a positive impact on the establishment of EFQM. Results of the fitting model indicated that the research data are fitting with the research conceptual model, so the model was verified. Based on the results of the hypotheses tests and given the fact that all the three hypotheses of the research were verified it was concluded that the strategic thinking directly and through the organizational learning affected on the implementation of the desired organizational model. Manuscript profile -
Open Access Article
273 - Solving N-Queen Problem Using Global Parallel Genetic Algorithm
Monire Taheri Sarvetamin Amid Khatibi BardsiriGreat efforts were made to solve uncertain hybrid optimization problems in the past few decades. The n-Queen problem is one of these problems that many solutions have been proposed for. The traditional methods to solve this problem are exponential in terms of runtime an MoreGreat efforts were made to solve uncertain hybrid optimization problems in the past few decades. The n-Queen problem is one of these problems that many solutions have been proposed for. The traditional methods to solve this problem are exponential in terms of runtime and are not acceptable in terms of space and memory complexity. In this study, parallel genetic algorithms are proposed to solve n-Queen problem. Parallelizing island genetic algorithm and the Cellular genetic algorithm was implemented and run. The results show that this algorithm has the ability to find related solutions to this problem. The algorithms are not only faster but also they lead to better performance even without the use of parallel hardware and just running on one core processor. Good comparisons were made between the proposed method and serial genetic algorithms in order to measure the performance of the proposed method. The experimental results show that the algorithm has high efficiency for large-size problems in comparison with genetic algorithms, and, in some cases, it can achieve superlinear speedup. The proposed method, in the present study, can be easily developed to solve other optimization problems. Manuscript profile -
Open Access Article
274 - Increasing the Customers Score through the EFQM Excellence Model in International Inspection Companies
Sanaz Rasouli Kamran Jamali FirouzabadiNowadays customer satisfaction in the service organizations has been found of considerable importance. In this regard, the most competitive index is the quality improvement of services to the customers in International inspection companies. To identify strengths & w MoreNowadays customer satisfaction in the service organizations has been found of considerable importance. In this regard, the most competitive index is the quality improvement of services to the customers in International inspection companies. To identify strengths & weakness points of these organizations for performance improvement, an appropriate system is needed to enable us for obtaining more concessions from the customers. Is this research new conceptual model of attaining more concessions from the customers in EFQM is studied. What in this research will be studied is “the DFD conceptual model is related to which customer based standards & criteria?” that if information transfer of inspection companies is diagramed on the basis of conceptual model, then concessions of points by the customers would be increased which lead to increase the total EFQM points of the companies. After that organizational excellence declaration forms which are filled by the customers would be evaluated by the assessor and desired behavior of organizational excellence would be recognized upon the answers to the questions in the mentioned form. If the questionnaire had been filled documentary, by evaluating answers & their efficient relation, establishing of EFQM conceptual model could be with high extent achievable. Therefore we can conclude that by implementing a DFD conceptual model, points by customers would be increased. Manuscript profile -
Open Access Article
275 - Investigation of the Strategic Thinking Role in Implementation of the EFQM Model through Organizational Learning within the Logistics Department of the Ministry of Energy and the Ministry’s Subsidiary Companies
Mehdi Etemadi Abdosamad KhodamiPresent research intends to look into the role of the strategic thinking in the implementation of the EFQM model through organizational learning within the logistics department of the Ministry of Energy as well as the Ministry's subsidiary companies. For this purpose, f MorePresent research intends to look into the role of the strategic thinking in the implementation of the EFQM model through organizational learning within the logistics department of the Ministry of Energy as well as the Ministry's subsidiary companies. For this purpose, four hypotheses formulation presented and tested. The present research is based on the three variables: The strategic thinking as the independent variable, implementation of the EFQM model as the dependent variable and organizational learning as the mediator variable. The current research method is applied research in terms of objective, strategies and data collection is solidarity, quantitative, and survey questionnaire respectively. In this survey, statistical society includes all managers and field staff working for the Ministry of Energy and subsidiary companies in Iran with the number of 35324 persons, who are serving in 2015. Sampling in this study is done based on random sampling method with stratified kind and Krejcie and Morgan table was designed for 384 people. Data analysis was conducted by applying the software such as SPSS statistical, Excel and Lisrel. The results of the proposed approach showed that strategic thinking and organizational learning both have a positive impact on the establishment of EFQM. Results of the fitting model indicated that the research data are fitting with the research conceptual model, so the model was verified. Based on the results of the hypotheses tests and given the fact that all the three hypotheses of the research were verified it was concluded that the strategic thinking directly and through the organizational learning affected on the implementation of the desired organizational model. Manuscript profile -
Open Access Article
276 - Investigating the spiritual intelligence of student teachers in order to achieve transcendent education
Pari Fahandezh saadi Abbas AnarinejadThe main purpose of this study was to investigate the level of spiritual intelligence of student teachers of Farhangian University of Shiraz to achieve transcendent education. This research is considered as a quantitative research in terms of nature and applied research MoreThe main purpose of this study was to investigate the level of spiritual intelligence of student teachers of Farhangian University of Shiraz to achieve transcendent education. This research is considered as a quantitative research in terms of nature and applied research in terms of purpose. The research method was field survey and the statistical population of the study included students of Shiraz Farhangian University in the academic year of 2019-2020, amongst which 310 people were selected using Cochran's formula by stratified random sampling method. Data were collected using the King Spiritual Intelligence Scale. The validity of the questionnaire was confirmed by experts and the questionnaire had a reliability of 0.87 which was done through Cronbach's alpha. The research data were analyzed using SPSS21 software with one-sample t-test and independent t-test. Students are in a relatively high position in terms of spiritual intelligence and its components (except for the expansion of the state of consciousness), but they are far from the desired level of adequacy. Meanwhile, there is a significant difference between the spiritual intelligence of male and female students. Manuscript profile -
Open Access Article
277 - Transcendent education in the light of the mental model of individual excellence of teachers
Meysam Ghavidel Mahbobeh Montazer AtaeiThe aim of the present study is transcendent education in the light of the mental model of individual excellence of teachers. The research is applied in terms of purpose and descriptive in terms of method and exploratory mixed in terms of analyzed data. Since the goal i MoreThe aim of the present study is transcendent education in the light of the mental model of individual excellence of teachers. The research is applied in terms of purpose and descriptive in terms of method and exploratory mixed in terms of analyzed data. Since the goal is to know the mental patterns of teachers in relation to individual excellence, the Q method has been used in the qualitative part. Participants in the quality section were 10 professors of the faculties of educational sciences, successful principals and deputies of schools in Khorasan Razavi province who were selected by purposive sampling. The participants completing the Q tables are 12 prominent education teachers with a brilliant record who were provided with the tables. In this study, prolonged engagement has been used for credibility in the qualitative part. To assess the validity of the data collection tool in the quantitative part, face validity was used and the researcher made the managers and officials of the company to endorse the Q options. For the reliability of the research tool, Cronbach's alpha method is used which shows the high reliability of Q expressions and their sorting results in Q diagram. The results showed that the highest consensus was on factor one (individual capabilities) as 15,994 and the lowest consensus was on factor three (professional capabilities) as 13,079. It should be noted that psychological capabilities ranked second in categorizing views. Manuscript profile -
Open Access Article
278 - Identification and analysis of factors affecting the performance excellence of the first secondary schools (case study: Abadan city)
Rahman Jalilian Davood Gholamrezaei Leila RajabiIntroduction: The indicators of organizational excellence models that are suitable for schools' conditions can be used as channels to improve schools' performance. Therefore, the purpose of the current research is to identify and analyze the effective factors on the exc MoreIntroduction: The indicators of organizational excellence models that are suitable for schools' conditions can be used as channels to improve schools' performance. Therefore, the purpose of the current research is to identify and analyze the effective factors on the excellence of the performance of the first secondary schools in Abadan city considering the document of fundamental evolution of education. Research methodology: The statistical population is the principals and teachers of the first secondary schools of Abadan city,and according to Morgan's table, the required sample size is 186 people. The methods of collecting information in this research are divided into two categories: library-based method for collecting the subject literature and research background, and field-based method for collecting information to confirm or reject research hypotheses. Findings: The theory test model in this research contains five main factors of leadership, policy and strategy, staff, partnerships and resources, and processes, each of which consists of a number of subscales. The factors of leadership, partnerships and resources each include 6 subscales, processes and staff each include 4 subscales, and policy and strategy includes 7 subscales. The results of the path coefficients between the factors also indicated that the policy and strategy have an effect of 0.193 on the leadership factor and the staff factor has a 0.490 effect on the policy and strategy factor. Conclusion: The factors introduced by the researcher (leadership, policy and strategy, staff, partnerships and resources, processes) with the approach of the document of fundamental evolution of education strongly influence the excellence of school performance. Manuscript profile -
Open Access Article
279 - The investigation of the relationship of identity styles and Cell-phone use in college students
محسن گل محمدیان مسعود برومند نسب علیرضا رشیدی آراس رسولیThis research was carried out with the purpose of investigation of the relationship of Cell-phone use and identity styles (commitment, informational, normative and avoidant) in college students. The sampling group consists of 392 students in Islamic Azad university Dezf MoreThis research was carried out with the purpose of investigation of the relationship of Cell-phone use and identity styles (commitment, informational, normative and avoidant) in college students. The sampling group consists of 392 students in Islamic Azad university Dezful branch were chosen with Cluster sampling method. The research instruments including Cell-phone -use Scale (Jenaro& et al, 2007) and identity styles (Berzonsky, 1989). Pearson correlation and multiple regressions (stepwise) were used to analyzing data. Findings showed that, there are significant negative relationship between identity styles (normative, commitment and informational with Cell-phone use in collegue students (p≤0./01). avoidant- confused identity styles have significant positive relationship with cell phone use. Also multiple regression showed that commitment and avoidant identity styles are able to predict Cell-phone use (RS=./30). Manuscript profile -
Open Access Article
280 - Developing a qualitative model of human capital excellence in Iran's Education and Training
kazhal shahriari Yahya Dadash Karimi Kave teimoornejad Dariush gholamzadHuman capital is considered the main asset and capital for the educational institution, the actions of the managers are in the construction of a transformational view and it is considered as the most fundamental indicator and component in the macro analysis of education MoreHuman capital is considered the main asset and capital for the educational institution, the actions of the managers are in the construction of a transformational view and it is considered as the most fundamental indicator and component in the macro analysis of education. The purpose of this research is to develop a qualitative model of human capital excellence in Iranian Education and Training. The present research is exploratory and fundamental in nature and purposeful in terms of sampling method. The data collection tool was a semi-structured interview, which reached theoretical saturation by conducting 1110 interviews. The data were analyzed using Glazier coding method and software (MAXQDA11). The findings showed that the human capital excellence model in Iran's education based on has 5 main categories and 31 sub-components, which in total constitute the effective components of the human capital excellence components of education and training. The qualitative model resulting from this research, taking into account causal factors such as the results, shows that is content goals (knowledge-cognitive), individual goals (psychological), metacognitive goals, and social goals and organizational structural goals. In the qualitative model of the excellence of human capital of Iran's education and training. Manuscript profile -
Open Access Article
281 - The consequences of self ability of human resources in governmental organizations in Iran
mohsen Gharakhani kumars Ahmadi adel salavatiControl-based approaches in management are becoming empowerment-based approaches that self-empowerment is the newest type of this approach. The aim of this study was to investigate the consequences of human resource self-empowerment in Iranian government agencies. In th MoreControl-based approaches in management are becoming empowerment-based approaches that self-empowerment is the newest type of this approach. The aim of this study was to investigate the consequences of human resource self-empowerment in Iranian government agencies. In this research, two documentary (library) and field methods were used to collect data, so that based on documentary method, the researcher obtained the information through vector jack by reviewing different texts. In order to use the field method, semi-structured interviews and questionnaires were used. The sample size was considered for the qualitative method of 40 individuals, among which 20 managers of governmental organizations who were familiar with the topics of self-empowerment and 20 experts and experts of the initial model were taken into account and in the quantitative method, using Cochran's formula, 72 people including employees of the Economic and Finance Affairs Department of Kurdistan province were selected by simple random sampling. The data collected in the field section, obtained from interviews, were analyzed using the research method of the foundation data and the data obtained from the questionnaire were analyzed using SPSS statistical software. Findings indicated that implications in two individual and organizational levels were identified as the consequences of self-capability phenomenon in Iranian government agencies; In this way, the 'job satisfaction' and 'human resource excellence' are among their individual consequences and 'transformation of the administrative system', 'reducing costs' and 'organizational excellence' are among organizational consequences. The results of measuring the implications of self-empowerment of resources in the formation of resources, outcomes. Manuscript profile -
Open Access Article
282 - Presenting a model of empowering female managers to succeed in crossing the glass ceiling
Elham Maleki Parvaneh Glard Seyed Sobhan Lavasani Seyed Ahmad hosseinigolafshaniThe main purpose of this study is to provide a framework for the transition of female managers through glass celling. Therefore, the present study is a qualitative research that has been done with a content analysis approach. After reviewing the theoretical foundations MoreThe main purpose of this study is to provide a framework for the transition of female managers through glass celling. Therefore, the present study is a qualitative research that has been done with a content analysis approach. After reviewing the theoretical foundations and existing models, a semi-structured interview was conducted with 18 experts in the field of empowerment, and then using an open and centralized coding strategy, the effective factors were counted and finally the framework was presented. Based on the findings, a theoretical model including 6 themes of glass celling effect, understanding of glass roof, effective factors, strategies and characteristics, transformational leadership and easy exit explains the career path of women according to There is a glass roof to reach senior management. The research findings show that female managers show transformative leadership behaviors and most importantly, the female instinct of female managers is in accordance with transformational leadership behaviors. As a result, women are more affected by individual barriers and are able to overcome the barriers of the glass ceiling by relying on their feminine instincts. Decreased productivity in a group that believes in obstacles to their progress; Increased stress and job pressure; Increase the likelihood of resignation and departure of employees who believed in the glass roof; Reduce work and organizational commitment; Decreased work motivation; Feelings of hopelessness are the consequences of believing in a glass celling. Manuscript profile -
Open Access Article
283 - Airport Human Resource Excellence Model (Comparative Approach)
Ali Yaghoubipoor Ali JafariIn the last decade, the aviation industry in the world has been considered as one of the most important axes of development and growth of developed and developing countries and has a special place in the economic, social, cultural and technological development programs MoreIn the last decade, the aviation industry in the world has been considered as one of the most important axes of development and growth of developed and developing countries and has a special place in the economic, social, cultural and technological development programs of developed and developing countries.This study was conducted to develop a model of airport human resource excellence (comparative approach). This research was applied in terms of purpose and in terms of qualitative approach and especially metacombination approach. In terms of research methodology, Sandlowski and Barroso seven-step method has been used and to achieve a comprehensive model of human resource excellence, seven steps must be taken and finally the model of airport human resource excellence (comparative approach) was identified. In order to check the validity of the content validity model based on the opinion of experts and for the reliability of the model, the kappa index was used and reported to an acceptable level. In order to determine the concepts and codes, after reviewing different models in reputable domestic and foreign scientific sites, as well as reviewing different texts and books, after identifying 35 different models, 21 models were selected and analyzed. The results of the analysis are 69 adaptive codes and 15 concepts (airport leadership and specialized management, airport human resource maintenance, airport human resource organization, airport human resource management, airport human resource provision, airport human resource planning and strategy, Development of airport staff career, application of airport human resources, change and integrated use of human resource management, functional results of airport human resource management, environmental and perceptual results of airport staff, safety and health results of airport customers, social results and union reactions, organizational results and productivity Airport, identified the cultural and structural results of airport human resources) and finally the research model was presented. Manuscript profile -
Open Access Article
284 - Interactions between muscle tissue and bone metabolism in arthritic mice model following three treatment methods, exercise, ozone and stem cells.
zahra hadadpor Hajar Abbaszadeh parvin farzanegiAims: Objective: a-actinin3, pgc-1α genes are involved in muscle changes related to bone problems. The aim of the present study was to determine the effect of three treatment methods, exercise, ozone and stem cells on regulatory and inhibitory factors affecting th MoreAims: Objective: a-actinin3, pgc-1α genes are involved in muscle changes related to bone problems. The aim of the present study was to determine the effect of three treatment methods, exercise, ozone and stem cells on regulatory and inhibitory factors affecting the interactions between muscle tissue and bone metabolism in arthritic mice model.Materials and methods: 63 male mice (average age 10 weeks and average weight 250 to 300 grams) into 9 groups; Healthy control, control-patient, patient-saline, patient-exercise, patient-ozone, patient-cell, patient-cell-ozone, patient-exercise-ozone and patient-exercise-cell were divided. Osteoarthritis was induced to mice by surgical method. The training program included 30 minutes of running on the treadmill without a slope at a speed of 16 meters per minute. 1 x 106 cells/kg were injected into mice. Ozone was injected in the tifofemoral joint line of the knee with a concentration of 20 µg/ml. The expression of α-actinin3, pgc-1α gene was measured by real time PCR method.Findings: cell+exercise, exercise+ozone, and cell+ozone groups caused a significant increase in the expression of a-actinin3, pgc-1α genes in the thigh muscle compared to the cell, exercise, and ozone groups (P<0.05). ). In the exercise+cell group, these changes were more evident.Conclusion: The results showed that a combination of exercise and cells with an increase in the expression of a-actinin3, pgc-1α genes of the thigh muscle can probably have beneficial effects on the interactions between muscle and bone in the arthritic rat model, and as a result, the risks of analysis and Reduce muscle weakness caused by the complications of arthritis. Manuscript profile -
Open Access Article
285 - A novel method for magnetic stem cell delivery to the spinal cord injury using magnet combination
majid poladian fatemeh mokhtari amir shamlooMagnetic stem cell delivery is a promising method for imaging and regenerating damaged cells. To increase the accuracy of delivering stem cells to the target tissue, a precise and cost-effective magnetic system is needed. In this research, a method for arranging magnets MoreMagnetic stem cell delivery is a promising method for imaging and regenerating damaged cells. To increase the accuracy of delivering stem cells to the target tissue, a precise and cost-effective magnetic system is needed. In this research, a method for arranging magnets to improve the efficiency of stem cell transfer has been designed. The effects of these magnets on the movement of stem cells have been investigated. Different magnets with different arrangements were used for stem cell transfer and compared with each other. This research focuses on three categories of nerve-producing stem cells: bone marrow mesenchymal stem cells, nerve stem cells, and induced pluripotent stem cells. The results show that the arrangement of four magnets, with the side magnets of opposite poles, is more accurate in bringing all three types of stem cells to the injury site. The designed magnetic system can improve the accuracy of delivery of various stem cells in the spinal cord compared to previous methods. Also, the results show that the proposed method is more efficient in the neural stem cell category than in other categories. This method can be a good alternative to invasive methods including surgery. Manuscript profile -
Open Access Article
286 - Examining the challenges facing the citizen sports of Kurdistan province and presenting the promotion model
mehdi ezati Yusuf Jalali Navid MahtabThe purpose of this study was to examine the challenges facing the citizen sports of Kurdistan province and to present a promotion model. The current research was qualitative and of thematic analysis type. The statistical community of this research was made up of expert MoreThe purpose of this study was to examine the challenges facing the citizen sports of Kurdistan province and to present a promotion model. The current research was qualitative and of thematic analysis type. The statistical community of this research was made up of experts. Purposive sampling method was used for sampling and 17 experts were interviewed based on theoretical saturation. The findings of this study showed: the challenges of advancing citizen sports in Kurdistan province are the focus of a network of themes that include 3 overarching themes and 9 organizing themes (1) contextual challenges (undesirability of sports infrastructure, economic problems prevailing in the society, environmental threats), (2) structural challenges (non-integrated management of citizen sports, weak management and policy-making, weak index and codified statistical system, inappropriate urban governance) and (3) behavioral challenges (dominance of political views on sports, change in citizens' lifestyles). Also, the promotion of citizen sports in Kurdistan province is the center of a thematic network that includes 3 comprehensive themes and 8 organizing themes (1) contextual support (efficient and targeted incentives, increasing the quality and quantity of the province's sports infrastructure), (2) structural support (financial support, health-oriented : The focus of urban design is integration and unity of approach in citizenship sports and the establishment of a modern and codified statistical system) and (3) behavioral support (development of the general culture of sports and awareness of society and attention to citizenship sports in urban management) Manuscript profile -
Open Access Article
287 - Interpretive structural modeling of components of athlete Endorsement
Kaveh Mirani Farshad Tojari Negar ArazeshOne of the most important ways that sports products and services can be introduced to consumers is promotion.Therefore, the aim of this study was to interpret the structural modeling of the components of athlete Endorsement The research method was mixed(qualitative-quan MoreOne of the most important ways that sports products and services can be introduced to consumers is promotion.Therefore, the aim of this study was to interpret the structural modeling of the components of athlete Endorsement The research method was mixed(qualitative-quantitative) and applied in terms of purpose First, the indicators and components of athletes'Endorsement are identified based on literature study and content analysis and comparative related research and interviews with experts and specialists, and then using the methodology of modern structural-interpretive modeling(ISM) analysis of the relationships between indicators. And athletes Endorsement components were determined and analyzed in an integrated manner;Finally, using MICMAC analysis, the type of variables was determined according to the effect on other variables. The results of the analysis showed that the personality type component of effective role, trustworthiness component, influential role and lovely personality components, having the desired grooming, communication ability,ability of appropriate personal characteristics, having the necessary acceptability, responsibility, professional honesty, Attitude, motivation and empathy play both effective and influential roles.In explaining these results, it can be said that Endorsement depends more on the component of personality type.The influential component of personality type is the most critical component, because Endorsement changes depend on the personality type component;Therefore, the amount of control over this variable is very important.On the other hand, this variable is the system input variables. According to the results, it is suggested that companies, organizations use celebrities in the discussion of sports certifiers who have a high personality type to be more effective in Endorsement. Manuscript profile -
Open Access Article
288 - Low Temperature Hydrothermal Synthesis and Characterization and Optical Properties of Sr5Nb4O15 – Nb2O5 Nanocomposite
Sh. Khademinia M. Behzad A. Alemi M. Dolatyari -
Open Access Article
289 - The creativity of the Celebrities in Instagram on the public policy process
mehdi soltanifar Ali Geranmayepour shahnaz HashemiBackground: It is noteworthy that the presence of the Celebrities in politics and Instagram pages provides the conditions to communicate directly with the audience. The benefits of celebrity from Instagram have to be creative and intelligent. According to Giddens' theor MoreBackground: It is noteworthy that the presence of the Celebrities in politics and Instagram pages provides the conditions to communicate directly with the audience. The benefits of celebrity from Instagram have to be creative and intelligent. According to Giddens' theory, creativity emerges with two factors of agency and structure Purpose: The aim of this study is to identify the relationship between the creativity of celebrities and the public policy process. Method: In order to understand the relationship between agency and structure in the emergence of Celebrities creativity, it is highly unlikely that a survey of 384 instagram users following the Celebrities pages would be possible. Conclusion: Respondents say there is an inverse relationship between the agency of the Celebrities and the perceived political problem. The structure and perception of the political problem is reversed, meaning that if the activity of political parties, media, political and intellectual elite decreases, and the presence of Celebrities will increase. But there is no relationship between Creativity in Problem Perception and Solution. At the law implementation stage in the policymaking process, there is a relationship between the effectiveness of Celebrities and law implement. There is a direct relationship between social structure and law implement. The more the function of parties, the media, the political and intellectual elites are used, the more the Celebrities as symbolic capital and the more the tendency of the Celebrities. There is also no correlation between the creativity of the Celebrities and the evaluation of law enforcement Manuscript profile -
Open Access Article
290 - Correction and processing of earthquake accelerograms
حجت اله TorkianAcceleration of ground motion in earthquake is recorded by accelerographs. For analogueaccelerographs (SMA-1), human and instrumental errors and in the case of digital ones (SSA-2), lowand high frequency noises would be included in accelerograms. In order to use the acc MoreAcceleration of ground motion in earthquake is recorded by accelerographs. For analogueaccelerographs (SMA-1), human and instrumental errors and in the case of digital ones (SSA-2), lowand high frequency noises would be included in accelerograms. In order to use the accelerographrecorded data in practical applications both, errors and noises, should be omitted. The main purpose ofthis paper is to find different types of errors and noises which appear in the accelerograms and then tointroduce appropriate methods to remove them as to maintain characteristics of the recordedearthquake. Correction methods are based on mean removal, base line correction, and high and lowfrequency removal by the use of low-pass and high-pass filters. Acceleration, velocity anddisplacement time history were used in processing earthquake signals in the time domain andfrequency content of earthquake was shown using frequency spectrum in frequency domain. All of theabove-mentioned corrections and processings were also applied to a raw accelerogram. The studyindicates that correction of accelerograms before application is inevitable. Besides, selection of cut-offfrequencies in order not to lose earthquake frequency content is not the same for various records andthe filtration process would be better done using the frequency amplitude spectrum related to theparticular accelerogram. Manuscript profile -
Open Access Article
291 - The feasibility study of applying an acid boric and glass infiltrated mica to prevent the leakage and mixture of use gasses for hightemperature fuel cells
Hamid Abdoli Alireza Hosseini Moghadam Seyed Amir RastialhosseiniIn this study, the possibility of using mica for this application was investigated. First, mica gasket includingsmall Phlogopite flakes with organic binders was used and its performance duringas leakage was simulated in asmall set-up simulating fuel cell operating condi MoreIn this study, the possibility of using mica for this application was investigated. First, mica gasket includingsmall Phlogopite flakes with organic binders was used and its performance duringas leakage was simulated in asmall set-up simulating fuel cell operating condition (air atmosphere, temperature of 800 °C and time of 100 h).Due to heating of mica during operation, binders were burned out and remaining pores acted as leakage path.These leakage paths were filled by acid boric and the mica performance was enhanced up to 20%. The majorleakage path (mica and its adjacent interface) was filled by a glass and a successful application of mica-glasslayer was obtained for leakage prevention. Manuscript profile -
Open Access Article
292 - valuation of the optimum dimension of installation pocket for pressure cell using numerical modeling
Kaveh Ahangari Seyed Mohsen Moosavi KojoriPressure cell is used to measure total stress in soil. There is possibility of the rotation of pressure cell duringthe fill compaction and damage due to traffic passage. So, the pressure cell is located in a pocket which isexcavated in soil. Unsuitable pocket dimension MorePressure cell is used to measure total stress in soil. There is possibility of the rotation of pressure cell duringthe fill compaction and damage due to traffic passage. So, the pressure cell is located in a pocket which isexcavated in soil. Unsuitable pocket dimension will prevent accurate measurement of pressure cell. In thisstudy a new model is introduced to determine the optimum dimension of the pocket and investigate theeffects of the pressure cell properties and the installation condition on results of this device in earth dam. Atwo dimensional finite different method, FLAC software, was used for this purpose. Results of modelingshowed that the width of each pocket must be about 3 times more than the diameter of the pressure cell andits height is equal to the diameter of installed cell. Manuscript profile -
Open Access Article
293 - Identification and Investigation of the Status of the Cultural Policy-Making Pattern’s Indicators Based on Islamic Management Philosophy in District Eight’s Payam-e-Noor Universities
Fatemeh Shahabi Nejad Hamdollah Manzari Tavakoli Mohammad Jalal Kamali Sanjar Salajegheh Hamid Reza Molaei -
Open Access Article
294 - Identifying and Prioritizing the Components of Organizational Excellence Model in Bushehr Maritime Command
Mohammad Musa Khorshidi Abdul Mohammad Taheri Alireza Ghasemi Zad -
Open Access Article
295 - Detecting and predicting vegetation cover changes using sentinel 2Data (A Case Study: Andika Region)
sedigheh emami esmail emamiThe earth surface is itself a complex system, and land cover variation is a complexprocess influenced by the interference of variables. In this study, the data of Sentinel 2for 2017 and 2016 were processed and classified to study the changes in the Andikaarea. After dis MoreThe earth surface is itself a complex system, and land cover variation is a complexprocess influenced by the interference of variables. In this study, the data of Sentinel 2for 2017 and 2016 were processed and classified to study the changes in the Andikaarea. After discovering vegetation changes between two images over the mentionedtime, vegetation increased by 661.74 hectares. Multiple regressions have been used toidentify factors affecting vegetation changes. Multiple regressions can explain therelationship between vegetation changes and the factors affecting them. In order toinvestigate the factors affecting vegetation change, altitude data, distance from theroad, distance from residential areas of the village and river were introduced intoregression equation. Since this method uses three parameters such as Pseudo-R2 andRelative Operation Characteristic (ROC(, 0.23, and 0.696 values for the aboveparameters, which indicates that the model is in good agreement. The results ofregression analysis show that linear composition of height variable as independentvariables in comparison with other parameters has been able to estimate vegetationchange. Subsequently, by using two classified pictures of 2017 and 2016, the amountof vegetation changes was calculated, and Markov chain method was used for 2018forecast changes. Manuscript profile -
Open Access Article
296 - Discovering and Recovering the Changes in Land Use and Land Cover Using Remote Sensing and GIS (Case Study Heev Village, Alborz Province)
zahra talebi banizi Zahra Naserian Mohammad Mazrae MolaeiDetecting changes is one of the basic needs in the management and evaluation of natural resources. Modeling the process of land cover changes over time using multi- time data in the GIS environment can act as one of the most important factors in managing the mentioned c MoreDetecting changes is one of the basic needs in the management and evaluation of natural resources. Modeling the process of land cover changes over time using multi- time data in the GIS environment can act as one of the most important factors in managing the mentioned changes. In order to modeling the process of land cover changes and to investigating the possibility of predicting it in the future, land change modeling (lcm) has been used. Therefore, the Landsat TM5 analyzer data of Heev village in Alborz province for the years 1985T 2000 and 2011 were analyzed. Next, using the maximum similarity method, land cover maps of each image for the mentioned years, was extracted and categorized into five layers of vegetation, city, asphalt, barren lands (soil) and rocks and cliffs. The extracted accuracy evaluation coefficients (overall accuracy and kappa coefficient) indicate the high accuracy of this classification method. The analysis of the results obtained from the studies conducted on the two periods of 1985-2000 and 2000-2011 shows an increase in urban construction with a decrease in vegetation, and even in some areas, the disappearance of vegetation, while the village is expanding towards the mountainside. Using the combination of Markov model and automatic cell maps land use prediction maps for the next 16 years were obtained, while the kappa coefficient was used to determine the prediction compliance, and comparing them with the actual map Manuscript profile -
Open Access Article
297 - A Survey of Hazarāt-i Vujūd (the Excellencies of Existence) from the View of Dihlavī and Shankara
zeinab panah Hazarāt-i Vujūd (the excellencies of existence) in the Islamic mysticism of Bīdil Dihlavī- a mystic, poet, and representative of the Indian style- is in a linear and descending system based on the theory of unity of being explained within the framework of the stat More Hazarāt-i Vujūd (the excellencies of existence) in the Islamic mysticism of Bīdil Dihlavī- a mystic, poet, and representative of the Indian style- is in a linear and descending system based on the theory of unity of being explained within the framework of the status of essence, oneness, and uniqueness. Although Bīdil is bought up in India, he is one of the intellectual followers of Muhy id-Dīn ibn Arabī. Shankara is also one of the most notable interpreters of Vedanta’s school or India’s divine philosophy. According to Indian thinking, the four states of Ātman include Jagrat (waking), Swapna (dreaming), Sushupti (deep sleep), and Turiya (unconditional Ātman). These four stages of existence are comparable to Hazarāt-i Vujūd in Islamic mysticism. Using a descriptive-analytic method and library means, the present article makes a comparison between the perspectives of Bīdil and Shankara about the quadruplet worlds of existence. According to the results, the realm of mysticism dealing with the most inner aspects of a human paves the way for a common perception between religious and instinctive instructions of different ethnic groups; and in addition to the similarities between the theories, we can also discern their differences. The most distinction between Hazarāt-i Vujūd in Bīdil’s Islamic mysticism and Shankara’s Indian style is that although both have a linear and descending course, the foundation of Bīdil’s mysticism is based on divinity and genuine oneness of God whereas in Shanka’s Indian mysticism, the emphasis is on Ātman or the real self. Manuscript profile -
Open Access Article
298 - Population fluctuation of egg parasitoids of sunn pest and determining of dominant species in Varamin and vicinity
Hasan GhahariPopulation fluctuation of sunn pests’ parasitoids (Scelionidae and Encyrtidae) was studied in 5 different localities of Varamin including, Javad-Abad, Dehmacin, Gharchak, Asgar-Abad and Pishva. Seven parasitoid species including, Telenomuschloropus, Trissolcusbasa MorePopulation fluctuation of sunn pests’ parasitoids (Scelionidae and Encyrtidae) was studied in 5 different localities of Varamin including, Javad-Abad, Dehmacin, Gharchak, Asgar-Abad and Pishva. Seven parasitoid species including, Telenomuschloropus, Trissolcusbasalis, Tr. grandis, Tr. rufiventris, Tr. semistriatus, Tr. vassilievi and Ooencyrtustelenomicida were collected from the mentioned regions. Upon the samplings in Gharchak, 4 species, T. semistriatus, T. grandis, T. Vassilievi and T. Rufiventris, were collected which of these T. semistriatus and T. grandis were determined as dominant species. Mean percent parasitism of T. semistriatus was higher than the other species and the highest parasitism (44.63%) was obtained in 22 May 2014. In Pishva, 5 parasitoids, T. grandis, T. vassilievi, T. semistriatus, T. chloropus and T. Basalis, were collected, which T. grandisand T. vassilievi were the dominant. The parasitism of these two parasitoids were started in 10 April 2014 and the maximum parasitism of T. grandis(27.89%) in 22 May 2014 and for T. vassilievi (22.39%) in 29 May 2014. Parasitoids of sunn pest in Javad-Abad were identified as T. rufiventris, T. grandis and Telenomus chloropus which of these, T. rufiventris was determined as the dominant species. The beginning of its parasitism activity was observed in 17 April 2014 and its maximum (26.44%) in 7 May 2014. The collected species in Dehmacin were included T. semistriatus, T. vassilievi, T. grandis and O. telenomicida which 2 species T. semistriatus and O. telenomicida were the dominant. The maximum percent parasitism was obtained in 22 May 2014 for T. semistriatus and 29 May 2014 for O. telenomicida. Six parasitoid species including, O. telenomicida, T. rufiventris, T. vassilievi, T. grandis, T. semistriatus and T. simony were collected from Asgar-Abad, which of these 3 first species were the dominant species. The highest percent parasitism for T. vassilievi(16.68%) and T. rufiventris (13.21%) was obtained in 22 May, 2014, and for T. grandis(23.72%)in 5 June 2014. Regarding to sex ratio of parasitoids, mean percent of emerged females was more than the male production in all sampled regions. Manuscript profile -
Open Access Article
299 - Efficacy of the stabilizers of Talaromyces flavus in biological control of sugar beet seedling damping-off disease
Sheedeh Mehraban Booshehri Laleh Naraghi Mohammad TorabiIn the present study, first the superior bioformulations for Talaromyces flavus,containging some chemical stabilizers were determined by measuring the presentage of active spores in bioformulations and then their efficacy in biological control of sugar beet seedli MoreIn the present study, first the superior bioformulations for Talaromyces flavus,containging some chemical stabilizers were determined by measuring the presentage of active spores in bioformulations and then their efficacy in biological control of sugar beet seedling damping-off was investigated in greenhouse. An experiment was performed in split plot based on randomized complete block design with four replications in greenhouse. Three inoculum application methods (soil treatment, seed treatment and combination of both methods) were considered as the main factor and eight different inoculum formulations including six superior bioformulations Dicycloserin-TF-Su-K-1,Dicycloserin-TF-Su-K-2,Dicycloserin-TF-Su-K-3, Carboxymethilcellolose-TF-Su-K-2, Sulfate magnesium-TF-Su-K-3 and Nitratesodium-TF-Su-K-2. together with two control treatments (healthy and infected checks) were considered as the sub-factor.The results indicated that the most effective treatments for biological control of sugar beet damping-off were Dicycloserin stabilizer and isolate TF-Su-K-3, separetely. Results of the interaction effects of inoculum application method and inoculum showed that the treatment of Dicycloserin-TF-Su-K-2 applied as soil treatment or as combination of soil and seed treatment resulted in less disease occurrance. Manuscript profile -
Open Access Article
300 - In vitro of essential oils effects on mycellial growth of Fusarium solani the causal of storage disease Fusarium Dry Rot of potato on their tubers.
Roya Tavousi Mohammad Torabi Hosain VafaeiThe use of antifungal compounds such as essential oils for the preservation of natural fruits during the storage period has dramatically been rising. In this study, the individual essential oils of Majorom (Origamum marjorana), wild mint (Mentha longifolia) and Summer s MoreThe use of antifungal compounds such as essential oils for the preservation of natural fruits during the storage period has dramatically been rising. In this study, the individual essential oils of Majorom (Origamum marjorana), wild mint (Mentha longifolia) and Summer savory (Satureja khuzistanica) were employed for the control of corruption of tubers during the storage period. In this study, the antifungal activity of essential oils was investigated on growth a specie of plant pathogenic fungus (Fusarium solani)on PDA medium and tuber tissues. Antifungal activity on PDA medium were measured by disk diffusion and volatile essential oil methods. To evaluate the effects of the essential oils on fungal growth in tuber tissue, the potato were inoculated with 30 µl of spore suspension (106 spore/ml), and then tubers were sprayed with 4 and 20 µl/ml of the essential oils. Seven days after inoculation, tubers were evaluated in terms of pollution. To calculate the percentage of infected tuber was divided into eight parts and the number of infected tuber fungus pathogen contamination in 12.5% multiplication and percentages were calculated. Data were analyzed as a completely randomized design with three replications. Essential oils has showed Significant inhibitory effect on fungus growth. The results showed that most inhibition of growth in a paper disk method was in order for fungus F. solani related to the essential oil of summer savory 59.41 percent, respectively and volatile essential oil methods was related to the essential oil of Summer savory was 41.12 percent respectively. The results inoculated of the tuber tissue with a spore suspension F. solani showed that respectively treatment (20µl/ml) of Majorom (with 27.08% of disease) had the most inhibitory against pathogen Manuscript profile -
Open Access Article
301 - Comparison of Implicit and Explicit Curriculum in the Development of High School Students’ Personality from Students’ Point of View
Rojina Ahmadpour Hassan Maleki Amir Hossein Mehdizadeh -
Open Access Article
302 - Effects of changes in some electrospinning parameters on fibroin nanofibers morphology
Amirasad Pourabadeh Shaghayegh SadrzadehSilk fibroin (SF) is a natural fibrous protein that has been widely studied for application in the biomedical field as a matrix for tissue engineering. Pure fibroin was extracted from silk cocoon by degumming method using aqueous Na2CO3 solution followed by solubilizing MoreSilk fibroin (SF) is a natural fibrous protein that has been widely studied for application in the biomedical field as a matrix for tissue engineering. Pure fibroin was extracted from silk cocoon by degumming method using aqueous Na2CO3 solution followed by solubilizing in CaCl2-C2H5OH-H2O aqueous solution and frozen in liquid nitrogen, then lyophilized in freeze-dryer. SF fibers with diameters down to the nanometer range are formed by subjecting a fluid jet to a high electric field. The electrospinning of the SF sponge was performed with formic acid, as a spinning solvent, at 7% (w/w) fibroin concentration. In this regard, electrospinning parameters including voltage, flow rate, and distance were used as variable parameters, and the effect of changes in these parameters was investigated. The morphology of SF nanofibers was characterized by SEM. As the flow-rate increased, the available polymer volume was high which increased the nanofiber diameter. Also the lower the solution flow-rate, the smaller the diameter of the resultant electrospun nanofibers and bead defects. With an increase in the distance between the capillary and the collector the nanofiber diameter initially decreased to a minimum and then increased. Manuscript profile -
Open Access Article
303 - A review on single cell oil production from food waste
Nahayeh Najafi Payman RajaeiSCO single cell oil is a suitable alternative source for oils, because it can be used as a raw material in the production of biofuels and also as a suitable option in the production of essential fatty acids suitable for human nutrition or as a supplement in animal feed. MoreSCO single cell oil is a suitable alternative source for oils, because it can be used as a raw material in the production of biofuels and also as a suitable option in the production of essential fatty acids suitable for human nutrition or as a supplement in animal feed. . However, the usability of SCO is limited due to the high price of the raw materials used in it. The fermentation process using inexpensive agricultural and industrial wastes can solve this problem, which are applicable for the production of SCO. The use of these by-products as the main source of carbon in fermentation not only significantly reduces the overall costs of SCO production, but also causes the treatment of produced waste streams, thus reducing the negative effects on the environment. . Because various agricultural and industrial biodegradable by-products can be used in microbial fermentations. The purpose of this review is to classify and compare usable agricultural residues based on their availability. Single-cell oils are lipids from bacteria, fungi, yeasts, microscopic cruciferous algae, and protists. These lipids have different uses depending on their fatty acid composition. SCOs with high saturated fatty acid content are suitable for biodiesel production, while SCOs rich in unsaturated fatty acids are suitable for human and animal nutrition. Manuscript profile -
Open Access Article
304 - Artificial intelligence in cancer diagnosis and treatment methods
javad safaei kuchaksaraei -
Open Access Article
305 - Experimental Investigation of a Hybrid System of Fuel cell/Thermoelectric for Waste Heat Recovery
نادر رهبر مصطفی حسنیIn this article, waste heat recovery from a PEM fuel cell using of thermoelectric generators has been experimentally evaluated. An experimental setup has been constructed which consists of a heat exchanger, thermoelectric modules and heat sink with built-in temperature MoreIn this article, waste heat recovery from a PEM fuel cell using of thermoelectric generators has been experimentally evaluated. An experimental setup has been constructed which consists of a heat exchanger, thermoelectric modules and heat sink with built-in temperature sensors. The setup is evaluated under operating conditions of a 5 kW PEM fuel cell. The results of the experimental setup shows that use of thermoelectric generators can be a good strategy for the recovery of waste heat from PEM fuel cells. For this purpose, the design of the heat exchanger in the hot and cold side of the thermoelectric are very important. Manuscript profile -
Open Access Article
306 - Numerical Simulation of Pollutant Dispersion from an Industrial Stack
Nima Amoozadeh Hadi Kargar Sharif AbadEnvironmental pollution is one of major ahead problems. To know the manner of dispersion of pollution and effecting parameters on it can be so useful to manage and reduce its effects. In the present work a two-dimensional geometry used to simulate a stack and the disper MoreEnvironmental pollution is one of major ahead problems. To know the manner of dispersion of pollution and effecting parameters on it can be so useful to manage and reduce its effects. In the present work a two-dimensional geometry used to simulate a stack and the dispersion domain. A CFD based approach used to investigate the effect of stack height, pollutant’s exit velocity and wind velocity, on the dispersion. Results show that in shorter stack the concentrate of pollutants on earth surface is more than longer one. However pollutants rise is not significant during moving and the maximum concentration is in the stack height limits. The higher wind velocity increases dispersion rate and exit velocity causes more rise of pollutants. Manuscript profile -
Open Access Article
307 - Construction reviewing the performance of a solar cell samples under climatic conditions Sabzevar software scaps
reza mazinani javad baedi mahdi mazinaniModern man is facing two major problems; On the one hand, fossil fuels are running out and the other side, these fuels environmental problems such as air pollution and the greenhouse effect, making them much. Solar cell is the best choice to replace fossil fuels. In thi MoreModern man is facing two major problems; On the one hand, fossil fuels are running out and the other side, these fuels environmental problems such as air pollution and the greenhouse effect, making them much. Solar cell is the best choice to replace fossil fuels. In this study, using the software scaps Initial simulation for solar cells has been considered. The investigation revealed that for best performance, Should be as thin with a thickness of 4 µm tin And zinc oxide used as window that if we can keep constant temperature of the solar cell at 300 K have the highest efficiency. Manuscript profile -
Open Access Article
308 - THE EXPERIMENTAL INVESTIGATION OF ENERGY ABSORBED AND MORPHOLOGICAL PROPERTIES OF ABS.
احسان صائمیAbstract The Microcellular foams are a group of foams which have a lot of micro cells in the size of about 10 microns. In these foams, neutral gases (Nitrogen or Carbon dioxide) are used as a foaming material. Because of their small sizes, these foams have better mecha MoreAbstract The Microcellular foams are a group of foams which have a lot of micro cells in the size of about 10 microns. In these foams, neutral gases (Nitrogen or Carbon dioxide) are used as a foaming material. Because of their small sizes, these foams have better mechanical and physical properties (such as fatigue strength, yield strength and de-electrical and thermal properties) than non-foamed plastics. In this study, the mechanical properties of polystyrene microcellular foams have been studied. The rate of relative density, the size of the cells, the structure of the foams and yield and fatigue strength have been studied and measured. To achieve an optimal structure, the results show that temperature and time of foaming should be controlled carefully. This condition is in the temperature of about 100° c and the time of 100 second. Also, the tensile strength of the foamed sample has been reduced and the rate of energy absorption has been significantly increased. Manuscript profile -
Open Access Article
309 - The study of the Mobility of charge carriers in Gallium Arsenide semiconductor doped with Cr and Co used in solar cell of space shuttles
hassan khaleghiGaAs is a binary III-V compound semiconductor in the periodic table. Having a direct energy gap of 1.42 eV at room temperature, GaAs is one of the widely used semiconductors in the technology and creation of solid state electronic devices such as solar cells. From this MoreGaAs is a binary III-V compound semiconductor in the periodic table. Having a direct energy gap of 1.42 eV at room temperature, GaAs is one of the widely used semiconductors in the technology and creation of solid state electronic devices such as solar cells. From this view point, study of the electronic properties of GaAs single crystals is of prime importance. In this experimental work, transport properties of two kinds of p-type GaAs samples each doped with Cr and Co have been studied in the wide temperature range (100-400) K. Apart from temperature dependency of mobility of charge carriers also different predominant scattering mechanisms occurring in these crystals have been given. Analysis of the temperature dependency of mobility, shows that, two kinds of scattering mechanisms namely, ionic and lattice scatterings are the dominant mechanisms at low and high temperatures, respectively. Manuscript profile -
Open Access Article
310 - Calculation of vehicle’s mass transfer due to road roughness in accelerating and braking maneuvers
Kazem Reza Kashyzadeh Ali Esfandi Seyed Majid Ataei Ardestani Hassan Ghafori VarzanehIn this paper, the main purpose is the calculation of mass transfer due to road roughness in different maneuvers including of the vehicle accelerating and braking. To achieve this goal, the damping model of a full car for 10 degrees of freedom, based on the vibrations i MoreIn this paper, the main purpose is the calculation of mass transfer due to road roughness in different maneuvers including of the vehicle accelerating and braking. To achieve this goal, the damping model of a full car for 10 degrees of freedom, based on the vibrations in MATLAB software was Simulated. Vertical displacement of the wheels on uneven roads based on ISO classification at a constant speed of 70 km per hour and the general direction of the vehicle was 1,000 meters. The following, using inverse dynamics analysis in MATLAB Simulink, the forces acting on each wheel of the vehicle during various maneuvers was obtained. Finally, using of force histories resulting in the wheels of to cross the road roughness, as well as accelerating and braking, rate of mass transfer from back to front in the braking maneuver and rate of mass transfer from the front to the rear of the vehicle in the accelerating maneuvers was obtained. Manuscript profile -
Open Access Article
311 - Study of the vibration behavior of vehicle body due to road roughness during accelerating motion
Kazem Reza Kashyzadeh seyed mohammad saleh mousavi bafrouyi saleh arabIn the present paper, the main purpose is study of the vibration behavior of vehicle body and its passengers due to road roughness during constant acceleration motion. In order to achieve this goal has been used a quarter model of sedan vehicle for both front and rear w MoreIn the present paper, the main purpose is study of the vibration behavior of vehicle body and its passengers due to road roughness during constant acceleration motion. In order to achieve this goal has been used a quarter model of sedan vehicle for both front and rear wheel. In this way, a quarter model of sedan vehicle with constant velocity and also accelerating motion on road of class D, according to ISO8606 standard, has been simulated by utilizing the finite element software. Thus, has been obtained applied forces to vehicle body during accelerating motion and also road roughness for both front and rear wheel. Manuscript profile -
Open Access Article
312 - The Electrical Conductivity of charge carriers in Gallium Arsenide semiconductor doped with Cr and Co used in solar cell and optical fiber detectors
hassan khaleghiGallium arsenide is a compound of the elements gallium and arsenic. It is a III-V direct band gap semiconductor with a zinc blende crystal structure. GaAs is used in the manufacture of devices such as microwave frequency integrated circuits, monolithic microwave integra MoreGallium arsenide is a compound of the elements gallium and arsenic. It is a III-V direct band gap semiconductor with a zinc blende crystal structure. GaAs is used in the manufacture of devices such as microwave frequency integrated circuits, monolithic microwave integrated circuits, infrared light-emitting diodes, laser diodes, solar cells and optical windows. GaAs is often used as a substrate material for the epitaxial growth of other III-V semiconductors including: Indium gallium arsenide, aluminum gallium arsenide and others. From this view point, study of the electronic properties of GaAs single crystals is of prime importance. In this experimental work, electrical conductivity of two kinds of p-type GaAs samples each doped with Cr and Co have been studied in the wide temperature range (100-400) K. Apart from temperature dependency of mobility of charge carriers also different predominant scattering mechanisms occurring in these crystals have been given. Manuscript profile -
Open Access Article
313 - Study of Effective Parameters on Velocity of Projectile Using
ساسان امینیان دهکردی امین کلاهدوز محسن لوح موسویelectromagnetic force is One of the fundamental forces and it is widely used in industry . the use of the electromagnetic force is different for example it can use for Electric engine , Contactor , etc. if it increase can use electromagnetic force in Forming , assemble, Moreelectromagnetic force is One of the fundamental forces and it is widely used in industry . the use of the electromagnetic force is different for example it can use for Electric engine , Contactor , etc. if it increase can use electromagnetic force in Forming , assemble, welding and Acceleration . Acceleration and To speed up of thing is newest Application , when object is in intense field and magnetic moment that is causing the acceleration and speed So this energy is Clean and quite for use to acceleration of airplane , projectile and etc. to do this research at first electromagnetic source was build then with study about effective parameters, chose wire diameter , length of coil , number of layer and tube material .use final element method (J-Mag and Abaqus ) for parameters impact on the theory. The final element test and experimental test had a good match. For analysis the output( velocity ) use minitab program. As result the coil with maximum layer and 150 mm length with wire diameter 2 is the best coil and high speed was achive with this coil and it about 431m/s. Manuscript profile -
Open Access Article
314 - Literature Review carried out in the field of solar Air heater
Ali Heydari mikaeel ForatiTo reduce energy sources, efforts are underway to optimize thermal processes around the world. Solar energy as an important source of renewable energy on Earth, with simple technology cause reduction in air pollution and saving the environment with less fossil fuels con MoreTo reduce energy sources, efforts are underway to optimize thermal processes around the world. Solar energy as an important source of renewable energy on Earth, with simple technology cause reduction in air pollution and saving the environment with less fossil fuels consumption for the future. One application of the solar energy is solar air heaters which different design is done for different application. To ensure the performance of energy systems, analysis of first and second laws of thermodynamics can be more useful to analyze processes undertaken within the system. Exergy is considered as a key concept and it is a fundamental concept of accessible energy. Solar air heaters can be based on its performance cycle was divided into two categories: active and passive. In passive systems mainly based on the difference in specific gravity of air, naturally flow of warm and cold air is formed. But in activated systems a forced convective air flow is derived with external component like fan. Manuscript profile -
Open Access Article
315 - Numerical evaluation of cooling heating system management performance in Lithium Ion batteries
mohammad ali farajollahi Mohammad Hassan Nobakhti morteza khayatThe main cause of failure and significant reduction in battery performance is a rise in temperature, so battery thermal control systems (BTMS) are built to monitor and optimize the thermal status of batteries. In this paper, two series and parallel arrangements for plac MoreThe main cause of failure and significant reduction in battery performance is a rise in temperature, so battery thermal control systems (BTMS) are built to monitor and optimize the thermal status of batteries. In this paper, two series and parallel arrangements for placing battery packs in electric vehicles with the same number of 17,280, 18650 battery cells are proposed and compared to select the best position for placing the battery packs. With the help of the Comsol program, the temperature change of the battery pack in the laminar fluid flow regime and the heat flux changes in the first 700 seconds of discharging the battery cells from the full charge mode and selecting the best design of the battery pack placement are compared. The maximum closed surface temperature of batteries is measured from the initial temperature of 27 degrees in series and parallel arrangement, respectively. The maximum temperature difference in the series of batteries is 10% different from the parallel arrangement. Also, by comparing the total heat flux, the better performance of the parallel arrangement compared to the arrangement of the battery series, makes this type of design a practical and more cost-effective priority than other designs. Manuscript profile -
Open Access Article
316 - Investigation and Prediction of Spatial and Temporal Land Use Changes in New Hashtgerd City by Integrating Remote Sensing Data and Cellular Automata Markov model
Sara SoukhtezariLand use changes due to the physical expansion of the city in most cities in Iran are so rapid, that urban planners and managers are facing a dynamic and complex development as they integrate the planning process in these areas. The purpose of this study is to investiga MoreLand use changes due to the physical expansion of the city in most cities in Iran are so rapid, that urban planners and managers are facing a dynamic and complex development as they integrate the planning process in these areas. The purpose of this study is to investigate land use changes and physical development of Hashtgerd city during the past 19 years and to predict land use change trends for the future. In this study, Landsat multi-time images were used. Using the support vector classification machine algorithm and the algorithm for Cross-Tab change, land use change trends over the past 19 years was evaluated. Also, using the Cellular Automata Markov prediction model, the process of land use change and physical expansion of the city is predicted for the future. The results of this study indicate the unnecessary expansion of the city over the past 19 years. So that the built-up with 736.56% growth have caused excessive destruction of agricultural and bare lands on the outskirts of the city. Investigations show that with increasing distance from land use changes have significantly reduced the amount of land use. Investigation of changes in land uses showed that 564/166 hectares of waste land has become residential land use. Predicting land use changes for 2028 and 2038 showed that residential land use will continue to increase. This highlights the need for special attention of urban planners and managers to the issue of urban development and its consequences in the region. Finally, the evaluation of the accuracy of the automated cell model showed that the percentage of classes area difference was less than 8%. Manuscript profile -
Open Access Article
317 - Prediction of Urban Construction Changes Using Satellite Images Based on CA-MARKOV Models (case study: Sari)
Sahab Bidgoli Kashani Mehran Fadavi Valiollah AzizifarAlong with the ever-increasing urban population, the amount of construction in the city space has been developed. The development of construction in the horizontal space and regardless of the existing restrictions has led to environmental, economic and legal problems fo MoreAlong with the ever-increasing urban population, the amount of construction in the city space has been developed. The development of construction in the horizontal space and regardless of the existing restrictions has led to environmental, economic and legal problems for the citizens. Achieving the amount, intensity and direction of construction development from the past to the present and predicting the construction situation in the future is the first step towards the scientific and practical management of the physical development of urban construction, planning and providing suitable solutions in order to create a balance between allocation Spatial-spatial construction and all kinds of legal, economic and environmental considerations. Data and information extracted from satellite images, while showing the historical changes of urban construction, are used as the main, necessary and necessary input data for models to predict its future state. In this research, satellite images of TM, ETM+ and OLI sensors of Landsat satellite were used in the time periods of 1997-2007 and 2007-2017 related to the city of Sari. After performing geometrical corrections, city area maps were prepared. Then, by using the effective parameters in urban construction changes, using the Cellular Automata(CA) Markov Model, the accuracy of the simulations was checked. Finally, for validation, the simulated maps and the ground reality map were matched with each other. The simulation of the construction development process in 2027 using the CA-Markov model showed that if the existing management regulations continue, this area will decrease from 4617.90 hectares in 2017 to 4357.44 hectares in 2027. But the examination of change maps and stability maps showed that new areas will be under construction between 2017 and 2027, which were mainly used for agriculture and barren land. Manuscript profile -
Open Access Article
318 - Identifying the consequences of implementing marketing excellence
جمال قادری نسب حسن اسماعیلپور منصوره علیقلی داریوش غلامزادهAbstractThe current research was conducted with the aim of identifying the consequences of implementing marketing excellence in the aviation industry. The research method was mixed and conducted in the qualitative phase based on the grounded theory method. The research MoreAbstractThe current research was conducted with the aim of identifying the consequences of implementing marketing excellence in the aviation industry. The research method was mixed and conducted in the qualitative phase based on the grounded theory method. The research community in the qualitative phase consists of aviation industry experts. The tool for collecting information in the qualitative phase is in-depth interview and interview protocol. The sampling method in the qualitative stage is purposeful and the sampling continued until reaching theoretical saturation and finally 20 interviews were conducted to analyze the data in the qualitative stage of the theme analysis method including open, axial and selective coding with soft help. MAXqda software is used. The results of the qualitative phase of the research show that marketing excellence consists of value creation components, being a market driver, marketing efficiency, marketing learning, social responsibility and ethical marketing. Causal conditions affecting marketing excellence include marketing knowledge, marketing strategies, internal marketing, relational marketing, integrated marketing, and performance marketing. Interactions include marketing research, target market strategies, positioning and marketing mix, and marketing excellence outcomes including customer-based achievements and financial, social and environmental achievements. The background conditions include the organization's mission, the organization's marketing culture, the organization's structure and marketing infrastructure.e. Manuscript profile -
Open Access Article
319 - Investigating the relationship between management excellence and the performance of employees of Islamic Azad University, Zahedan branch
نواب سپاهیان علیرضا سرگلزاییAbstractIn terms of method, this research is descriptive and survey type. Based on the purpose, this research is an applied research and in terms of time, it is part of applied research. In terms of the type of data collection, this research is among library and field r MoreAbstractIn terms of method, this research is descriptive and survey type. Based on the purpose, this research is an applied research and in terms of time, it is part of applied research. In terms of the type of data collection, this research is among library and field research. The statistical population in this research, the employees of Islamic Azad University, Zahedan branch, includes 300 people, and a statistical sample was made from this population based on the Morgan table and by the simple random sampling method, which includes 169 employees. The tool for collecting information in this research is a researcher-made questionnaire containing questions on the effectiveness of staff performance and the excellence of university management. In order to check the validity of the questionnaire, the content validity method was used in this research. The CVR method was used to calculate the reliability coefficient of the judges, and the obtained coefficient was 0.89, which indicates the appropriateness of the tool. Also, to determine the reliability of the test, Cronbach's alpha method was used, in which 20 questionnaires were initially measured and the results obtained (0.91) showed the reliability of the tool. In this research, SPSS 24 and Amos software were used for data analysis. The research findings have shown that there is a significant relationship between management excellence and each of the components of employee performance. Manuscript profile -
Open Access Article
320 - Sellectted Mullttiinattiional l Entterpriises:: An Assessmentt iin Phiilliippiine
دکتر علیرضا حبیبی -
Open Access Article
321 - Some Suggestions on Urartian Inscription of Tul-e Talesh Bracelet
Maryam DaraUrartians expanded their kingdom in the area between Lakes Sevan, Van and Urmia for about three centuries from 9th century B.C. The bronze bracelet with Urartian inscription from Tul-e Talesh has been studied by the scholars as a proof of Urartian border expansion and t MoreUrartians expanded their kingdom in the area between Lakes Sevan, Van and Urmia for about three centuries from 9th century B.C. The bronze bracelet with Urartian inscription from Tul-e Talesh has been studied by the scholars as a proof of Urartian border expansion and their effects on the region or even as a looted object. This inscription is known to belong to Argišti I or Sarduri II. But the solder in the bracelet has been the cause of arguments and also distractions from other details. The inscription was written with two sorts of epigraphy and with no sufficient attention. Therefore the era when this inscription was written is hard to be determined. The inscription contains only two words as mar-giš-ti and uš-tú-ú. The second part is incomplete and could be uš-tú-ú-ni or uš-tú-ú-ri or uš-tú-ú-li. The author of this paper suggests that it was possible for this object to be moved from one site to another as an ancient tradition. It is also possible that the inscription was cut from another longer inscription and was made into a bracelet with adornments. The words in the beginning and the end of the inscription are incomplete and it is also possible that the metalworker cut the word Argišti for any reason and used another part (ni-še uš-tú-ú) with no attention or knowledge of Urartian grammar. Therefore, the translation is useless as there are two words of “Argišti” and “dedicate”. “ḫi” as a paternal sign could have possibly been hidden under the solder as well. The poor epigraphy of the inscription is the reason for the author not to accept the idea of the bracelet as a temple dedication. Manuscript profile -
Open Access Article
322 - The effect of intra-myocardial injection of secretion of bone marrow-derived mesenchymal stem cell on Myocardial infarction in male rabbits
narges kakadezfuly maryam naseroleslami nahid aboutalebBackground and Aim: Despite the use of stem cells in the treatment of diseases, especially heart disease, there is a lot of ambiguity about the act of cells and their secretions. Therefore, the purpose of this study was to evaluate the effect of secretion of bone marrow MoreBackground and Aim: Despite the use of stem cells in the treatment of diseases, especially heart disease, there is a lot of ambiguity about the act of cells and their secretions. Therefore, the purpose of this study was to evaluate the effect of secretion of bone marrow-derived mesenchymal stem cells on myocardial infarction in male rabbits. Materials and Methods: After isolating the stem cells from the bone marrow and preparing the conditioned medium, 30 Male rabbits were randomly divided into three groups(n=10). Myocardial Infarction was induction in two groups and in a group conditioned medium was injected into the hearts of rabbits. Then in the first, fourth and eighth weeks, the heart parameters (HF, EF) were measured by echocardiography and then TNF-α factor was measured in the serum. Heart tissue was removed and the level of angiogenesis and fibrosis were investigated. Results: In the treated group with conditioned medium, the heart parameters (HF, EF) and angiogenesis increased significantly and decrease the level of TNF-α factor and fibrosis was significant in comparison with the Myocardial Infarction group (P<0.05). Discussion: Since the cardiac tissue and its function improved in this research, it seems that the secretion of bone marrow-derived mesenchymal stem cells have therapeutic effects on myocardial infarction. Manuscript profile -
Open Access Article
323 - Determining of non-toxic dose of Fe3O4 magnetic nanoparticles on amniotic membrane stem cells
neda mousaviniri maryam naseroleslamiSuperparamagnetic iron oxide nanoparticles (SPIONs) are an Important advancement in the field of nanotechnology. They expand the possibilities of noninvasive analysis for tracking of cells and have many useful properties, making them potential candidates for numerous ap MoreSuperparamagnetic iron oxide nanoparticles (SPIONs) are an Important advancement in the field of nanotechnology. They expand the possibilities of noninvasive analysis for tracking of cells and have many useful properties, making them potential candidates for numerous applications in medicine. However, the possibility of toxicity in cells is reported by these nanoparticles. The goal of this study was to find a concentration of SPIONs that cant induce intracellular levels of Reactive Oxygen Species. For this purpose for the first time amniotic membrane stem cells were incubated with different concentrations of SPIONs coated with polyethylene glycol (PEG). Then intracellular levels of Reactive Oxygen Species was measured By probe Rhodamine 123 . Our results demonstrate that there was no significant generators of Reactive Oxygen Species in cells in concentration range of 0-100 μg/mL of spions. However, at concentrations higher than 100 μg / ml, the production of Reactive Oxygen Species increased. According to the results nanoparticles used in this study at concentrations ≤100 μg/mL are suitable for tracking of this cells. Manuscript profile -
Open Access Article
324 - Investigation on germination and phenolic content of tomato (Solanum lycopersicum) in response to cell phone radiation
Elham Rajabbeigi Mohammadreza RoustaNowadays, the use of cell phone has increased with the modernization. It has led to the increase in the radiations in the environment which further has effect on the plants and animals including human beings. In this research, the grains of tomato (Solanum lycopersicum) MoreNowadays, the use of cell phone has increased with the modernization. It has led to the increase in the radiations in the environment which further has effect on the plants and animals including human beings. In this research, the grains of tomato (Solanum lycopersicum) were placed in petridish and the mobile phone set was placed over them and it was activated by calling from another phone. The grains under the treatment for 14 days, were radiated for 10 minutes every day. After the treatment, the effects of cell phone waves on tomato (Solanum lycopersicum) seedlings were investigated and the percentage of germination, radical scavengering capacity, and phenolics were examined in compared to control samples. It was observed that radiations emitted from cell phone show considerable increasing in the germination percentage and lipid peroxidation. Radical scavenging activity (RSA) and protein content were declined in response to cell phone radiations. Increasing of seed germination could be caused by inducing gene expression in response to cell phone radiations. It seems that although the decrease in radical scavenging activity, ROS was increased. It could be led to lipid degradation in compare to control ones. Total phenolics decreased in response to phone radiation. It seems that cell phone radiation can affect cells through the membrane degeneration and the production of reactive oxygen species. Manuscript profile -
Open Access Article
325 - Association study of polymorphisms rs3761548 in FOXP3 gene and Migraine disease
Leila Solgi Sedigheh Farahani شهره زارع کاریزیBackground: FOXP3 is required for the generation and function of regulatory T (Treg) cells. The gene is involved in regulation of inflammatory responses and neuronal cell development. Migraine is an inflammatory disease and is considered as a polygenic multifactorial di MoreBackground: FOXP3 is required for the generation and function of regulatory T (Treg) cells. The gene is involved in regulation of inflammatory responses and neuronal cell development. Migraine is an inflammatory disease and is considered as a polygenic multifactorial disease, and it seems that many genes are involved in this disease. The aim of the present study is to determine if any relation exists between foxp3 rs3761548 gene polymorphisms on the individual susceptibility of migraine. Materials and methods: In this study, 148 patients with clinically definite migraine and 149 ethnically-matched healthy controls participated. Genotyping was performed using PCR-RFLP method for the mentioned polymorphisms in the FOXP3 gene. Logistic regression test were used for estimating odd ration and 95% CI by using SPSS ver.16 software. Results: No significant difference in distribution of foxp3 rs3761548 alleles and genotypes was found in females and males with a history of migraine in comparison to control (p=0.08). Conclusion: This is the first report concerning the association between foxp3 gene polymorphisms and migraine. The further study of FOXP3 related pathways and gene networks might result in the better understanding of the pathophysiology of migraine and related symptoms. Manuscript profile -
Open Access Article
326 - The Effect of Tilia platyphyllos extract on Varicocele-Induced Testicular Sperm Parameters in Adult Male Wistar Rats
reyhaneh mohebali Akram Eidi pejman Mortazavi mohamad amin edalatmaneshAbstractThe reproductive system of men with varicocele is affected by the negative effects of oxidative stress on the testicles. In traditional medicine, the linden (Tilia platyphyllos L.) is used as a medicine to treat stomach ulcers, spasms and sedatives. Chemical com MoreAbstractThe reproductive system of men with varicocele is affected by the negative effects of oxidative stress on the testicles. In traditional medicine, the linden (Tilia platyphyllos L.) is used as a medicine to treat stomach ulcers, spasms and sedatives. Chemical compounds such as terpenoids and flavonoids have been identified in the linden. The aim of this study was to evaluate the effect of linden extract on testicular pathology of healthy and varicocele rats. In this study, 48 rats were randomly divided into 8 groups: Healthy control, healthy groups receiving linden extract (50, 100 and 200 mg / kg intragastrically, daily) alone, Infertile control (varicocele surgery), varicocele groups together with linden extract (50, 100 and 200 mg / kg intragastrically, daily). After 60 days, sperm analysis was performed and data were analyzed using one-way analysis of variance.Our results showed that sperm analysis was significantly decreased in infertile control animals compared to the normal control group. linden treatment prevented sperm changes and caused a significant increase in sperm parameters of infertile animals and decreased varicocele damage and protected the natural structure of the testis. Our results suggest that linden acts as a potent antioxidant against varicocele-induced damage in the rat. Manuscript profile -
Open Access Article
327 - The effect of synthetic silver nanoparticle from hydroalcoholic extract Digitalis nervosa on CDH1, Bax , Bcl2 and P53 gene expressions in cervical cancer cell line)Hela(
nazila ahmadzadeh nastran asghari moghaddam zahra keshtmandNowadays, metal nanoparticles, especially silver, due to their special physical properties and anti-cancer effects have been considered.One of the methods of synthesis of these nanoparticles is the use of plant extracts. The aim of this study was to investigate the anti MoreNowadays, metal nanoparticles, especially silver, due to their special physical properties and anti-cancer effects have been considered.One of the methods of synthesis of these nanoparticles is the use of plant extracts. The aim of this study was to investigate the anti-cancer effects of silver nanoparticles synthesized of the hydroalcoholic extract of Digitalis nervosa on the cancer cell line (Hela).In this experimental study,the synthesis of silver nanoparticles was performed by adding the hydroalcoholic extract of Digitalis nervosa to the silver nitrate solution. Physical and chemical properties of synthesized nanoparticles were determined by UV-vis, TEM, SEM, EDX and XRD methods.Viability of Hela cancer cells by MTT method with different concentrations of synthesized silver nanoparticles(3.125 to 100 mg/ml) and the expression of Bax, Bcl2, P53 and CDH1 genes were evaluated using real time PCR technique in 24 hours.Data were analyzed using GraphPad software and one-way ANOVA test.P<0.05 was considered statistically significant.The results showed that the results of cytotoxicity at different concentrations of silver nanoparticles showed that IC50 was16.66 μg /ml, respectively. Also, the expression of Bax, CDH1 and P53 apoptotic genes in concentration-(16.66μg/ml) increased and Bcl2 gene expression decreased compared to the reference gene, which showed the effects of cytotoxicity and changes in nanoparticle concentration. Silver nanoparticles synthesized from the extract of the Digitalis nervosa plant have a cytotoxic effect and possibly induce apoptosis on Hela cancer cells. Manuscript profile -
Open Access Article
328 - Evaluation of the growth regulators, sugars and amino acid tryptophan effect on the rate of tryptophan decarboxylase enzyme on Vinca major L. in tissue culture, cell suspension culture and field culture conditions
Ali Kazemzadeh fariba khosravinejad Amirhossein Kazemzadeh HaghighiThis study was performed to investigate the effect of growth regulatory treatments on the activity of tryptophan decarboxylase (TDC) which is a cytosolic enzyme and a key enzyme in the secondary metabolites Pathway with two subunits,115-118 KDa, molecular mass and depen MoreThis study was performed to investigate the effect of growth regulatory treatments on the activity of tryptophan decarboxylase (TDC) which is a cytosolic enzyme and a key enzyme in the secondary metabolites Pathway with two subunits,115-118 KDa, molecular mass and dependent on pyrodoxal phosphate (B6), Km75µmole for typtophan with optimal activity at alkaline pH of 7.5 in V.major hypocotyl. Some of simultaneous use growth regulators KIN, BA, NAA and IAA in three concentrations (0.1, 0,5, 1,0 mg/L) as well as various treatments of sucrose, fructose and glucose in 3 concentrations (2% , 4% , 6%) and also the amino acid tryptophan in concentrations (100 and 200 mg/L) were used to measure the amount of enzyme TDC activity, which was performed in three replications as a factorial in a completely randomized farm design of Karaj Seed and Plant Breeding Research Institute. In both of IAA and NAA at concentrations of 0.5 mg/L increases the amount of enzyme TDC in It has become about 10%. But in cytokines, KIN and BA at 1,0 mg/L had the greatest effect of about 40%. Sugars such as Sucrose in concentrations 6%, fructose and glucose in 4% and amino acid tryptophan in concentration 100 mg/l had the best effect on the activity of enzyme TDC in three replications as Factorial in the form of a completely randomized design in some cases. Manuscript profile -
Open Access Article
329 - Isolation and molecular identification of yeast cells and their evaluation for producing yeast extract and beta glucan
zohreh ranjbar majid baserisalehiYeast is a unicellular fungus with thick cell wall and nucleus. Nowadays this microorganism considered as important fungi in commercial industry because of their products specially yeast extract and beta glucan. The purpose of this study was isolation and identification MoreYeast is a unicellular fungus with thick cell wall and nucleus. Nowadays this microorganism considered as important fungi in commercial industry because of their products specially yeast extract and beta glucan. The purpose of this study was isolation and identification and screening of yeast cells for production of beta glucan and yeast cells. Yeast cells were isolated from plant and dairy samples and destruction of their cell walls was carried out using acidic condition, kiwi extract and change of osmotic pressure methods. In addition, isolation, purification and verification of beta glucan were done by modified Acid/Alkaline and Callose and Proton nuclear magnetic (H1NMR) methods respectively. The results obtained indicated that yeast cells were isolated from all samples. Two yeast cells based on their sizes and potential of growth were selected for further study. 18SrDNA gene sequencing of isolated strains identified them as Kluyveromyces marxianus and Saccharomyces cerevisiae. Our finding indicated that kiwi extract and change of osmotic pressure were favorable methods (p≤0.05) for production of yeast extract. Furthermore the results of Callose and H1NMR methods verified the production and purification of beta glucan. Hence based on our results production of beta glucan in industry scales is possible in our country Iran. Manuscript profile -
Open Access Article
330 - Investigating the impact of cerium oxide (CeO2) nanoparticles on structural and ultrastructural changes of marigold (Calendula officinalis L.) leaves
Sedighe Jahani Malihe Jahani Sara Saadatmand Homa Mahmoodzadeh Ramazan Ali Khavari-NejadIntroduction: Cerium oxide nanoparticles (CeO2 NPs) are one of the most widely used NPs in the world and their interaction with the ecosystem is unavoidable. Aim: The aim of this study was to investigate structural and ultrastructural changes in marigold leaves under Ce MoreIntroduction: Cerium oxide nanoparticles (CeO2 NPs) are one of the most widely used NPs in the world and their interaction with the ecosystem is unavoidable. Aim: The aim of this study was to investigate structural and ultrastructural changes in marigold leaves under CeO2 NPs. Materials and methods: Seeds were sown in pots under greenhouse conditions and after two weeks, seedlings were exposed to CeO2 NPs (0 and 3200 μg/mL) by leaf spray for five weeks. Then, leaf morphological changes were measured. Also, sampling from the control and NPs treatment leaf were performed to investigate structural and ultrastructural changes. Tissue preparation was performed and samples were examined by light and transmission electron microscopy (TEM). Results: Morphological changes including diminish in the length, width and area of marigold leaf under CeO2 NPs were observed. Also, ultrastructural changes of mesophilic cells of marigold leaf under CeO2 NPs including diminish of chloroplasts number and their swelling, incement of peroxisomes number, disintegration of cell membrane, and accumulation and deposition of NPs in the intercellular spaces, cell wall and membrane, vacuole, peroxisome and chloroplast stroma were observed. In addition, the results of cerium elemental assessment by methods of inductive coupled plasma emission spectrometry (ICP-OES) and energy dispersive X-ray spectroscopy (EDX), in line with TEM results, showed the uptake and accumulation of CeO2 NPs in marigold leaves. Conclusion: Ultrastructural damage in TEM results indicated the toxicity of high dosage of CeO2 NPs at the cellular level. Therefore, potential of hazardous impacts of CeO2 NPs on other medicinal plants and environment should be considered. Manuscript profile -
Open Access Article
331 - Examining GLUT1 mRNA level in tissue samples of non-small cell lung cancer
Fatemeh Saedvand Mehdi Ebrahimi Shohre Zare KariziIntroduction: Lung cancer is a type of malignant lung tumor, which is the most important cause of death caused by cancer in humans. GLUT1 is an important transporter of glucose to cells, and its over expression is involved in increasing the metabolism of cancer cells.Ai MoreIntroduction: Lung cancer is a type of malignant lung tumor, which is the most important cause of death caused by cancer in humans. GLUT1 is an important transporter of glucose to cells, and its over expression is involved in increasing the metabolism of cancer cells.Aim: Investigating changes in GLUT1 gene expression in non-small cell cancer tissue samples.Materials and Methods: Number of 30 tissue samples of non-small cell lung cancer and 30 tissue samples adjacent to the tumor were obtained from patients referred to Masih Deneshvari Hospital after obtaining consent. After sampling, RNA isolation and cDNA production, GLUT1 and GAPDH mRNA level was measured by Real-Time PCR technique. Statistical analysis of gene expression data was done with t test. Results: In 21 samples (70%), GLUT1 mRNA level in non-small cell lung cancer tissue was increased compared to healthy tissue. In addition, the level of mRNA in tumor tissue increased by 3.4 times compared to normal tissue (P = 0.013).Conclusion: The increase in GLUT1 mRNA level in non-small cell lung carcinoma cells can be a sign of changing the metabolic program of these cells to aerobic glycolysis, which results in tumor expansion and malignancy. Manuscript profile -
Open Access Article
332 - The effect of incremental aerobic exercise after injection of bone marrow-derived stem cells on some indicators of oxidative stress and inflammatory of liver tissue in rats model of fatty liver
hamed Namdar Seyed Abdollah Hashemvarzi Abdorreza Jafari ChashmiIntroduction: Non-alcoholic fatty liver disease is one of the most common liver diseases of this century, which is associated with changes in inflammatory cytokines and increased oxidative stress.The purpose of this research was to investigate the effect of an increasin MoreIntroduction: Non-alcoholic fatty liver disease is one of the most common liver diseases of this century, which is associated with changes in inflammatory cytokines and increased oxidative stress.The purpose of this research was to investigate the effect of an increasing aerobic exercise period after bone marrow stem cell injection on some indicators of oxidative and inflammatory stress of liver tissue in rats model of fatty liver. Methods: 60 adult male Wistar rats were divided into two main groups: control (6 rats) and patients with fatty liver (54 rats). The control group used standard rodent food for 6 weeks, while the animals in the diseased groups used high-fat food to induce fatty liver disease. At the end of the sixth week, to confirm the development of fatty liver disease, blood was randomly drawn from the tails of 3 mice and ALT and AST enzymes were measured. Then the animals of the patient group were randomly divided into 5 groups: Saline, Fatty liver, Exercise, Cell, Exercise + Cell. About 105 cells in 2 microliters of medium were injected into the cell receiving groups for each rat through the tail vein. The training program consisted of 8 weeks of incremental treadmill running.Results: The levels of CAT and SOD increased in the treated groups, but the level of the inflammatory index TNF-α decreased, but these changes were significant only in the groups of exercise and exercise + cells compared to the fatty liver group.Conclusion: Incremental aerobic training after the injection of bone marrow-derived stem cells increased the antioxidant levels of CAT and SOD and decreased the inflammatory index of TNF-α in mice with fatty liver. Therefore, it seems that this method can improve liver condition and be considered as a therapeutic solution. Manuscript profile -
Open Access Article
333 - Gait Generation for a Bipedal System By Morris-Lecar Central Pattern Generator
sahar Farshbaf Rashidi Mohammad-Reza Sayyed Noorani Maryam Shoaran Ahmad Ghanbari -
Open Access Article
334 - Lead-Lag Controllers Coefficients
نورالدین قدیمی -
Open Access Article
335 - Fuel Cell Voltage Control for Load Variations Using Neural Networks
Zolekh Teadadi Hassan Changiziyan -
Open Access Article
336 - Raising Power Quality and Improving Reliability by Distribution Network Reconfiguration in the Presence of Renewable Energy Sources
Mohamad Taghi Babajani BaghmisheZad Hosein NasirAghdam -
Open Access Article
337 - Increasing the Efficiency of Photovoltaic Systems by Using Maximum Power Point Tracking (MPPT)
Alireza Tofigh Rihani Majid Ghandchi -
Open Access Article
338 - The Role of Cellars in Reducing Energy Consumption in the Residential Architecture of Iran
Hossein Soltanzadeh Mersa Bideli -
Open Access Article
339 - Investigating the impact of social capital on the organizational excellence of the employees at the Islamic Azad University of Sari
Abolghasem BarimaniAbstract This study examined the impact of social capital on organizational excellence of staffs at Islamic Azad University of Sari. The study adopted an applied descriptive survey as its methodology. The statistical sample of the study comprised all employees at Islam MoreAbstract This study examined the impact of social capital on organizational excellence of staffs at Islamic Azad University of Sari. The study adopted an applied descriptive survey as its methodology. The statistical sample of the study comprised all employees at Islamic Azad University of Sari summing up to 259 subjects. Using Kerjecie and Morgan table, 170 employees were selected through stratified random sampling based on gender. a researcher–made questionnaire was used to collect data the face and content validity of which were determined by experts and certified professionals in the field and the reliability was estimated to be 0/88 using Cronbach's alpha. To analyze the data, descriptive and inferential statistics were used. The results of the study showed that all three dimensions of social capital including structural, cognitive and communication aspects had a positive impact on organizational excellence and the cognitive aspect had the greatest impact on organizational excellence and structural and communication aspects were placed next, respectively Manuscript profile -
Open Access Article
340 - A study on the effect of spiritual leadership and resiliency on organizational excellence among of Islamic Azad Universit’s in Khorasan Razavi Province
مهدی کفاش farshideh zameni Reza Yousefi SaeedabadiThis study aims to investigate the effect of spiritual leadership and resiliency on the organizational excellence among of Islamic Azad Universit’s Khorasan Razavi Province .The survey type ofdescriptive research method was used to conduct the research. The study MoreThis study aims to investigate the effect of spiritual leadership and resiliency on the organizational excellence among of Islamic Azad Universit’s Khorasan Razavi Province .The survey type ofdescriptive research method was used to conduct the research. The study population included all faculty members of Islamic Azad University of Khorasan Razavi Province. totally1,200 people that 291 of them were selected randomly as sample using Morgan table.The required datawere gatheredthrough three standardized questionnaire including Spiritual Leadership Questionnaire byFry et. al (2005), Corner Davidson Resilience Scale (2003) and Muller’s organizational excellence questionnaire (2000) .The validity of the questionnaires was confirmed by the experts in the field based on content validity .The reliability of the instruments was calculated 94% for spiritual leadership questionnaire, 87% for Resiliencequestionnaire and83% for organizational excellencequestionnaire using Cronbach's alpha.Descriptive statistics (frequency, graph ...) and inferential statistics (SEM) were used for data analysis. Analyzing the research results concerning the impact of spiritual leadership and resiliency dimensionson the Excellenceit was found that statistically spiritual leadership and resiliency had positive and direct impact on organizational excellence.So based on the above it can be concluded that the higher the dimensions of spiritual leadership and resiliency in an organization of Islamic Azad Universit’s Khorasan Razavi Province the higher will be the increase in organizational excellence. Manuscript profile -
Open Access Article
341 - The relationship between management by value and organizational excellence in Mazandaran Islamic Azad University
Abolghasem BarimaniThe aim of this study is the investigation of the relationship between management by value and organizational excellence in Mazandaran Islamic Azad University. This study is objectively application AL and methodologically correlational descriptive. Statistical populatio MoreThe aim of this study is the investigation of the relationship between management by value and organizational excellence in Mazandaran Islamic Azad University. This study is objectively application AL and methodologically correlational descriptive. Statistical population of this study includes all faculty members with the rank of Assistant professor Associate professor and professor that were 472. Statistical samples were 212 and selected by the use of Cochran formula and they have been chooser by random stratified sampling. We have used researcher self-made question air of management by value and standard question air of EFQM model. For gathering data congestive and formal validity have been approved by experts and authorities its reliability was achieved by Cronbach's Alpha formula and they were 0/98 and 0/97 respectively. We have used descriptive statistical and deductive statistical (regression and Pearson correlation test) for data analysis. Results showed that there are a significant relationship and positive correlation between management by value and organizational excellence. There is also a positive and significant relationship between management by value dimension (strategic, operational, social and personal) and organizational excellence. These dimensions dedicated 80.6 percent of organizational excellence changes to one personal values have the most important role in predicting organizational excellence, and social, operational and strategic dimensions are respectively in the next ranks. Manuscript profile -
Open Access Article
342 - 2500-year-old kingdom celebration with emphasis on cultural-social review the regim in Iran.
loghman dehghan houra shojaei2500-year-old kingdom celebration which after years of providing propaganda and studying were held in the fall of 1350 in persepolis with a unque glory , was on of the most expensire celebration which cost over 300 million dollars.By holding such a celebration ,shah was More2500-year-old kingdom celebration which after years of providing propaganda and studying were held in the fall of 1350 in persepolis with a unque glory , was on of the most expensire celebration which cost over 300 million dollars.By holding such a celebration ,shah was seeking a way to continue his government and dominance over the pepole of Iran ,so he began to recover Aryan's valuas and arouse animosity towards Islam and develop friendly relation with foreign countries ,hence he began a series of controversial and , in some cases ,useful measures :naming himself "shah", ordering the collection and compiliation if some books about Iran's pre-Islamic culture and civilization ,founding Shahanshahi foundation of Iran Acadmy ,establish-ment of Iran's National Deed Registery ,holding various celebrations during the celebration decade (1345-1355),promoting people to choose their children the original Iranian names ,sending some educational groups callend "Sepahyane Danesh" (knowledge corps)to villages for the aim of making pepole eager to ancient and kigdom culture and informing them of the magnitude of the 2500-year-old kingdom celebrations ,building several schools and many buildings of public interest after the name of cirus the Great,changing the calender from solar to kingdome the cost of these celebrtions was so high and anti-Islamic measurs of regime were so extensive that finally raised the protest of the majority of the pepole of Iran and even foreign press and figures,and Shah and regime were condemned. Manuscript profile -
Open Access Article
343 - Investigating the impact of social capital on the organizational excellence of the employees at the Islamic Azad University of Sari
fatemeh sograsina abolghasem barimani rashid zaheriThis study examined the impact of social capital on organizational excellence of staffs at Islamic Azad University of Sari. The study adopted an applied descriptive survey as its methodology. The statistical sample of the study comprised all employees at Islamic Azad Un MoreThis study examined the impact of social capital on organizational excellence of staffs at Islamic Azad University of Sari. The study adopted an applied descriptive survey as its methodology. The statistical sample of the study comprised all employees at Islamic Azad University of Sari summing up to 259 subjects. Using Kerjecie and Morgan table, 170 employees were selected through stratified random sampling based on gender. a researcher–made questionnaire was used to collect data the face and content validity of which were determined by experts and certified professionals in the field and the reliability was estimated to be 0/88 using Cronbach's alpha. To analyze the data, descriptive and inferential statistics were used. The results of the study showed that all three dimensions of social capital including structural, cognitive and communication aspects had a positive impact on organizational excellence and the cognitive aspect had the greatest impact on organizational excellence and structural and communication aspects were placed next, respectively. Manuscript profile -
Open Access Article
344 - A study on the effect of spiritual leadership and resiliency on organizational excellence among of Islamic Azad Universit’s in Khorasan Resave Province
mehdi kafash farshedeh zameni reza yosefi saedabadiThis study aims to investigate the effect of spiritual leadership and resiliency on the organizational excellence among of Islamic Azad Universit’s Khorasan Razavi Province .The survey type ofdescriptive research method was used to conduct the research. The study MoreThis study aims to investigate the effect of spiritual leadership and resiliency on the organizational excellence among of Islamic Azad Universit’s Khorasan Razavi Province .The survey type ofdescriptive research method was used to conduct the research. The study population included all faculty members of Islamic Azad University of Khorasan Razavi Province. totally1,200 people that 291 of them were selected randomly as sample using Morgan table.The required datawere gatheredthrough three standardized questionnaire including Spiritual Leadership Questionnaire byFry et. al (2005), Corner Davidson Resilience Scale (2003) and Muller’s organizational excellence questionnaire (2000) .The validity of the questionnaires was confirmed by the experts in the field based on content validity .The reliability of the instruments was calculated 94% for spiritual leadership questionnaire, 87% for Resiliencequestionnaire and83% for organizational excellencequestionnaire using Cronbach's alpha.Descriptive statistics (frequency, graph ...) and inferential statistics (SEM) were used for data analysis. Analyzing the research results concerning the impact of spiritual leadership and resiliency dimensionson the Excellenceit was found that statistically spiritual leadership and resiliency had positive and direct impact on organizational excellence.So based on the above it can be concluded that the higher the dimensions of spiritual leadership and resiliency in an organization of Islamic Azad Universit’s Khorasan Razavi Province the higher will be the increase in organizational excellence. Manuscript profile -
Open Access Article
345 - Religious scholars role in educational development in province qahistan
amir koochi Mahmood Kajehmirza ardeshir asadbeigiabstract:Qahistan is a region in the historical geography of Iran that has a huge and inseparable connection with Greater Khorasan. Although today most of it is called South Khorasan and some of its northern regions are part of Khorasan Razavi, but Qahstan has witnessed Moreabstract:Qahistan is a region in the historical geography of Iran that has a huge and inseparable connection with Greater Khorasan. Although today most of it is called South Khorasan and some of its northern regions are part of Khorasan Razavi, but Qahstan has witnessed historical events in its historical course.Due to its geographical location and cultural context in the field of education and training, Qahistan province has played a special role in Islamic culture and civilization from Afshari to the end of Qajar, so that great scholars emerged from this province and important factors such as political, social, economic and cultural The educational situation in Ghohestan has been influential. The method of collecting information in this research is based on the descriptive-analytical method of collecting resources and library documents. It has paved the way for excellence and advancement of education, so that the establishment of public schools politically and economically as a highway and culturally intellectual and ethnic pluralism are the main factors in improving the educational situation of Qahistan and stability in this area. It is possible.Therefore, the position of schools in the quality of education in Qahistan province has played a very important role in promoting the cultural insight of this province, so much so that it has nurtured elders, dignitaries and scientific masters and scholars of religiosity. Manuscript profile -
Open Access Article
346 - Historical role of sects and religions in Genesis jurisprudential schools
ghorban ali esmaileIslamic education began learning the learning of Koran. So it is obvious that there must be a strong connection between Islamic education and religious issues. Emergence of different religions and the demise of Mohammad Rasoul-allah (PBUH), followed the religious, polit MoreIslamic education began learning the learning of Koran. So it is obvious that there must be a strong connection between Islamic education and religious issues. Emergence of different religions and the demise of Mohammad Rasoul-allah (PBUH), followed the religious, political and social rivalries using historical methodology. This study is intended to clarify the influence of religious rivalries emergence of different faiths and the efforts of religious celergymen to develop social-political influence in emergence of schools. Study of the sources and refrences shows that religions political and social rivalries have been effective in emergence of the first schools. Celergymen, sometimes, in the form of ideological defense, and sometimes for developing a large-scale hnfluence, spending their properties or mulem's or using political force as well as financial of statemen have established schools. Manuscript profile -
Open Access Article
347 - The factor of Seljuk’s attention ceremony and ancient traditions
Amir AkbariThe seljuk’sage is one of the important periods of Iran history and Asia minor. Entry this population factor to Asia history area was accompany with major political and cultural developments. The Seljuk were first government among the Islamic states that car MoreThe seljuk’sage is one of the important periods of Iran history and Asia minor. Entry this population factor to Asia history area was accompany with major political and cultural developments. The Seljuk were first government among the Islamic states that carried the their government territorial till Byzantine borders and recovered the greatness of ancient empire. In regard this success, the Seljuk applied multiple effort into cultural look and attention to manner and ancient tradition. Seljuk‘s attention for the creation a great empire must be combined with emphasis on all of the political, administrative and cultural structures. Being BoghazKoy inscription in 1400 B.C into Ankara has the mark of attention to gods and ancient olden rituals in this lands. Nowruz celebration- Sadeh celebration and Mehregan celebration with itself ancient history was people‘s attention of Asia central till Asia minor. So, Seljuk into manage of the wide lands, addition creation a religious unity make efforts to cultural unity and emphasis on ancient traditions. Khayyam‘s effort for foundation an exact calendar without error and complexity was more on necessity return Nowruz to itself real time, namely ,first month Farvardin in per year. All of the efforts can not except, in the Seljuk ‘s power and Seljuk ‘s attention. Manuscript profile -
Open Access Article
348 - 2500-year-old kingdom celebration with emphasis on cultural-social review the regim in Iran.
L. Dehghan Nayyeri H. Shojaei2500-year-old kingdom celebration which after years of providing propaganda and studying were held in the fall of 1350 in persepolis with a unque glory , was on of the most expensire celebration which cost over 300 million dollars.By holding such a celebration ,shah More2500-year-old kingdom celebration which after years of providing propaganda and studying were held in the fall of 1350 in persepolis with a unque glory , was on of the most expensire celebration which cost over 300 million dollars.By holding such a celebration ,shah was seeking a way to continue his government and dominance over the pepole of Iran ,so he began to recover Aryan's valuas and arouse animosity towards Islam and develop friendly relation with foreign countries ,hence he began a series of controversial and , in some cases ,useful measures :naming himself "shah", ordering the collection and compiliation if some books about Iran's pre-Islamic culture and civilization ,founding Shahanshahi foundation of Iran Acadmy ,establish-ment of Iran's National Deed Registery ,holding various celebrations during the celebration decade (1345-1355),promoting people to choose their children the original Iranian names ,sending some educational groups callend "Sepahyane Danesh" (knowledge corps)to villages for the aim of making pepole eager to ancient and kigdom culture and informing them of the magnitude of the 2500-year-old kingdom celebrations ,building several schools and many buildings of public interest after the name of cirus the Great,changing the calender from solar to kingdome the cost of these celebrtions was so high and anti-Islamic measurs of regime were so extensive that finally raised the protest of the majority of the pepole of Iran and even foreign press and figures,and Shah and regime were condemned. Manuscript profile -
Open Access Article
349 - Iranian religious celebrations During the Sassanid
shmsodein najmiZoroastrians are always a celebration, praise and thanksgiving were celebrated today some of them as a national symbol and a symbol of monotheism and the ancient Iranian civilization. The separation of religion from many aspects of life difficult and perhaps impossible MoreZoroastrians are always a celebration, praise and thanksgiving were celebrated today some of them as a national symbol and a symbol of monotheism and the ancient Iranian civilization. The separation of religion from many aspects of life difficult and perhaps impossible ancient Persians and knowledge of the culture and civilization of ancient Iran today strongly intertwined with religion is. Ancient Iranians, happiness and divine gift in religious ceremonies to give thanks for the blessings that they had Ahura Mazda, was celebrated. Some of them have faded over time, and some celebrated as a national aspect and all Iranians from every ethnic and religious are most welcome. In this article, the most important religious feast mentioned Zoroastrians and the nature and cause them to be discussed. Manuscript profile -
Open Access Article
350 - Optimization of carotenoid pigment extraction from tomato using industrial hemicellulase enzyme
arezoo ghadiIn this study, the process of separating lycopene carotenoid pigment from tomato powder by industrial hemicellulose enzyme was studied. For this purpose, the effects of temperature change, enzyme concentration, incubation time, pH were all studied at optimum points. The MoreIn this study, the process of separating lycopene carotenoid pigment from tomato powder by industrial hemicellulose enzyme was studied. For this purpose, the effects of temperature change, enzyme concentration, incubation time, pH were all studied at optimum points. The research is based on the effectiveness of the enzyme in different conditions on the amount of pigments extracted from tomato powder and obtaining the optimal extraction points by statistical analysis of the results. To extract the pigment in this study, solvents of hexane, ethanol, acetone in a ratio of 1: 2:1 and incubation at 30 ° C for 16 hours were used for the full effectiveness of the solvent. For each variable, three levels were defined. In order to target the experiments, Taguchi design was used for the experiment design table and included nine experimental rows. For each experimental row, three replications and a control containing an enzyme-free sample were considered. Pigment-containing solutions were transferred to spectrophotometry at the end of the separation stage and after recording the data and statistical analysis, it was observed that the effectiveness of the enzyme concentration variable was much higher than other variables, so that the highest average pigment extraction concentration at 500 μg = .0.450 Separately, each variable has optimal points for the incubation temperature of 40 degrees and for the incubation time of 60 minutes, for pH = 4, the enzyme concentration is 200 micrograms per liter for every 5 grams of tomato powder. Manuscript profile -
Open Access Article
351 - A New Multi-Wave Cellular Learning Automata and Its Application for Link Prediction Problem in Social Networks
Mozhdeh Khaksar Manshad Mohammad Reza Meybodi Afshin Salajegheh -
Open Access Article
352 - LA-Based Approaches to Infer Urban Structure from Traffic Dynamics Considering Costs
Hamid Yasinian Mansour Esmaeilpour -
Open Access Article
353 - Cluster-Based Image Segmentation Using Fuzzy Markov Random Field
Peyman Rasouli Mohammad Reza Meybodi -
Open Access Article
354 - Fast Cellular Automata Implementation on Graphic Processor Unit (GPU) for Salt and Pepper Noise Removal
Afsaneh Jalalian Babak Karasfi Khairulmizam Samsudin M.Iqbal Saripan Syamsiah Mashohor -
Open Access Article
355 - The Impact of the Indigenous Model of Organizational Excellence (Designed) in Iranian Government Organizations
Mohamad Taherirozbahani Reza Najafbigi seyed Mehdi Alvani Gholamreza MemarzadehAbstract: The main objective of this research is to investigate the native model of organizational excellence in governmental organizations of Iran. The research is descriptive-correlative and purposeful, applied and fundamental, based on field and library research. The MoreAbstract: The main objective of this research is to investigate the native model of organizational excellence in governmental organizations of Iran. The research is descriptive-correlative and purposeful, applied and fundamental, based on field and library research. The statistical population of this study is the official staff of the Ministry of Industry, Mines and Trade (583 persons) and the sample is set at 234 people using the Morgan and Tacman tables. Sampling method in this research was simple random sampling and data on variables were collected through a researcher-made questionnaire (Cronbach's alpha = 988/0). Data were analyzed using software (Spss, Lisrel and PLS), and t-value, chi-square test, correlation coefficients, and least partial second power (PLS) method were used to answer the hypotheses. The results indicate that drives have a significant effect on the systems. Drivers have no significant effect on the results and the systems have a significant effect on the results. Manuscript profile -
Open Access Article
356 - Designing a model of organizational ethics excellence for Iranian government organizations
masoud haghighat shahrestani Ali Asghar pourezzat gholamreza memarzadeh tehran Naser HamidiEthics is one of the phenomena that has emerged from the beginning of the formation of official civilizations in history and has a very long history. The religion of Islam considers a healthy life to depend on the excellence of morality. Along the way, many organization MoreEthics is one of the phenomena that has emerged from the beginning of the formation of official civilizations in history and has a very long history. The religion of Islam considers a healthy life to depend on the excellence of morality. Along the way, many organizations also find goodness and charity as their ladder of development. The existence of all kinds of shortcomings and gaps, as well as the tendency for ethical orientation in organizations, has provided an opportunity to produce and develop models of ethical excellence in organizations. Designing a model of organizational ethics excellence in the light of Nahj al-Balagheh will help meet the needs of Iranian organizations for organizational excellence excellence. The present study is a qualitative research in which content analysis was used to analyze the data. MAXQDA software was used for structured classification of topics. In terms of reliability, ratio and content validity index, it was approved by experts. A distinctive feature of the designed model is the emphasis on spirituality and proper management of organizational ethics excellence. With this view, within the government organization itself, moral excellence has become a task, attention to competence and responsibility, process optimization, ethical auditing, ethical models, professional solution of organizational problems and creating common moral interests with extra-organizational elements. Manuscript profile -
Open Access Article
357 - The pattern of New communication Technologies impact on Media organization agility
Minoo Tashakori mohammad Dadgran Akbar NasrollahiNowaday, in changing and competitive world, one of the essential factors for survival and competitive advantage for agile media organizations is to increase their ability to respond, understand and manage change and use it as an opportunity. New technologies, as an impo MoreNowaday, in changing and competitive world, one of the essential factors for survival and competitive advantage for agile media organizations is to increase their ability to respond, understand and manage change and use it as an opportunity. New technologies, as an important lever, play a key role in developing agility without which it would be impossible to achieve the speed and flexibility that are the concepts of agility. The present study aims at explaining the influence of automation, one of the new technologies, in the agility of media organizations and providing a model for the impact of automation on agility through the use of mixed method (quantitative content + survey analysis). The statistical population of this research is university professors in media and communications management, active and retired staff and managers of IRIB. Data gathering tools are interviews and questionnaires. Quantitative content analysis and descriptive and inferential statistics were used to analyze the data. The research findings indicate: New technologies are an effective tool for “speed”, “flexibility”, “Responsiveness” and “competency”. These four components are the necessities to an organization excellence which have direct effect on agility. Finally, it is hypothesized that the relationship between the use of new technologies and the agility of media organizations has been designed and presented in a new paradigm. Manuscript profile -
Open Access Article
358 - Identifying Key Criteria of Excellence in the Public sector
naser mir sepasi gholam reza memarzadeh akbar alam tabrizToday encouraging quality in both public and private sectors is essential. Models and tools for managing private sector has surpassed those concerning public sectors. Given the fact that public sector has its own characteristics and circumstances, the model of the priva MoreToday encouraging quality in both public and private sectors is essential. Models and tools for managing private sector has surpassed those concerning public sectors. Given the fact that public sector has its own characteristics and circumstances, the model of the private sector will benefit them. So encouraging the organizational excellence, most of the firms use the techniques and tools to measure the excellence of their performance . One of the tools organizations are using is the business excellence model. This Paper Seeks to present an excellence model in the Iran public sector. In the first stage of the research, basics and context of organizational excellence, features of excellent organization and organizational excellence models are reviewed. In the next stage, comprehensive policies of Administrative system of Iran, Administrative system reform Plans of Iran, the civil service management, twenty-year vision of Iran with Qualitative approach using content analysis were analyzed to assess the context factors in excellence model,. The basic model of the research drew on the literature review and context factors in Iran. Sampling was judgmental and purposeful. Public sectors managers comprises the statistical sample. The instrument of the research was Questionnaire. Content Validity test and Cronbach’s alpha for reliability were used. Statistical analysis methods was explorative factor analysis. This study shows that main criteria of organizational excellence model of the research are seen in two areas (enterprise resources management and citizen relationship management) and core values are in three areas (human dignity, wisdom orientation and vision orientation). Manuscript profile -
Open Access Article
359 - An integrated model of cellular manufacturing and supplier selection considering product quality
Habib Heydari Mohammad Mahdi Paydar Iraj Mahdavi -
Open Access Article
360 - Cell forming and cell balancing of virtual cellular manufacturing systems with alternative processing routes using genetic algorithm
Adib Hosseini Mohammad Mahdi Paydar Iraj Mahdavi Javid Jouzdani -
Open Access Article
361 - Trajectory Planning Using High Order Polynomials under Acceleration Constraint
Hossein Barghi Jond Vasif V. Nabiyev Rifat Benveniste -
Open Access Article
362 - A simulated annealing algorithm to determine a group layout and production plan in a dynamic cellular manufacturing system
Reza KiA Nikbakhsh Javadian Reza Tavakkoli-Moghaddam -
Open Access Article
363 - Design of Accelerated Life Testing Plans for Products Exposed to Random Usage
Kamyar Sabri-Laghaie Rassoul Noorossana -
Open Access Article
364 - Developing a Multi-objective Mathematical Model for Dynamic Cellular Manufacturing Systems
Mohammad Saidi-Mehrabad Seyedeh Maryam Mirnezami-ziabari -
Open Access Article
365 - Study and Implementation of Lean Manufacturing in a Garment Manufacturing Company: Bangladesh Perspective
Ripon Kumar Chakrabortty Sanjoy Kumar Paul -
Open Access Article
366 - Designing Stochastic Cell Formation Problem Using Queuing Theory
Parviz fattahi Bahman Esmailnezhad Amir Saman Kheirkhah -
Open Access Article
367 - A Benders� Decomposition Approach for Dynamic Cellular Manufacturing System in the Presence of Unreliable Machines
Masoud Bagheri Saeed Sadeghi Mohammad Saidi-Mehrabad -
Open Access Article
368 - Layout of Cellular Manufacturing System in Dynamic Condition
amir hossein kamali dolatabadi seyed hamid reza pasandideh mehrzad abdi khalife -
Open Access Article
369 - Seismic Hazard Analysis of Golsar district in Rasht Metropolis.
Fatemeh Fekri Kateh Sari Mir Mohammad Seyed Hashemi Seyed Ali Razavian Amrei -
Open Access Article
370 - Performance of Mid-rise Buildings with Tubular Structure Under the Effect of Near Field Earthquakes
Hooman Mazlooma Maryam Firoozi Nezamabadi -
Open Access Article
371 - An Investigation into a Geocell-reinforced Slope in the Unsaturated Numerical Model
Behnam Mehdipour Hamid Hashemalhosseini Bahram Nadi Masoud Mirmohammad Sadeghi -
Open Access Article
372 - Numerical Modeling of the Effect of Geocell Elements’ Dimensions on Behavior of Circular Footings
Soheil Ghareh -
Open Access Article
373 - The Generation of Earthquake PGA Using Stochastic Finite Fault Method in Alborz Region
Ali Delnavaz Mohammad Ali Habibzadeh Ali Hajsayedtaghiya -
Open Access Article
374 - The Effect of Compressive Strength Reduction of Column Section Expose due to Freezing-Thawing Cycles on the Seismic Performance of Bridges
Saeideh Alsadat Mousavi Mehran Seyed Razzaghi -
Open Access Article
375 - Confirmatory Factor Analysis of Dimensions and Components of Organizational Excellence in Mazandaran Islamic Azad University
Abolghasem BarimaniThe aim of this study is dimensions confirmatory factor analysis and organizational excellence components in Mazandaran Islamic Azad University. This study is objectively applicational and methodologically correlational descriptive. Statistical sample has been selected MoreThe aim of this study is dimensions confirmatory factor analysis and organizational excellence components in Mazandaran Islamic Azad University. This study is objectively applicational and methodologically correlational descriptive. Statistical sample has been selected by random stratified sampling in terms of university campus and they were 212 of full-time faculty members with the rank of assistant professor, associate professor and professor. EFQM model standard questionnaire has been used to gather data. Congestive and formal validity has been approved by experts and authors. Questionnaire validity has been estimated as 0/97 by Cronbach's Alpha coefficient. Data analysis has been done by descriptive and deductive statistics methods, confirmatory factor analysis and structural equation modeling in SPSS software and smart PLS. confirmatory factor analysis results showed that there is a positive and meaningful relationship between organizational excellence components and dimensions in Mazandaran Islamic Azad University. It can also be stated by the factor that 96/7 percent of organizational excellence can be explained by enablers dimension and 96/5 percent by results dimension. Manuscript profile -
Open Access Article
376 - The Study of Guidance School and Biology High School Teachers’ Awareness of Modern Scientific Technology
Tahereh Khanjani Kamyan Khazaei Hosseinali Taghipour This study aimed to investigate the knowledge of modern descriptive-cross-sectional technologies in secondary and high school teachers in western Mazandaran. Thel science. nuclear power, and fundeta is a questionare consisting of 37 questions on internet science, More This study aimed to investigate the knowledge of modern descriptive-cross-sectional technologies in secondary and high school teachers in western Mazandaran. Thel science. nuclear power, and fundeta is a questionare consisting of 37 questions on internet science, it, nano technology, b population included all 116 science and biology teachers in Nowshahr, Chalous, and Tonekabon. The data collection instrument was a questionnaire consisting of 37 questions on Internet Science, IT, Nano Technology, Biotechnology, Nuclear Power, and Fundamental Cell Science. The data were analyzed by means of collective tables, X² test. The results showed the poor knowledge of the above technologies all over the country. On the contrast, teachers liked to have the subjects in curriculums. Moreover, their lack of presenting the subject could be traced in their fear to get involved in it due to their poor knowledge of them. Manuscript profile -
Open Access Article
377 - Evaluation of Grain Yield and Some Agronomic Traits of Tow Corn (Zea mays) Varieties as a Second Crop under Drought Stress and Application of Cycocel
M. Roshdi M. Yarnia F. HashemzadehTo evaluate grain yield and some agronomic traits of tow corn varieties as a second crop under drought stress and application of cycocel an experiment was conducted at Agricultural Research Station of Jahad-Keshavarsi of Khoy during summer growing season of 2005. MoreTo evaluate grain yield and some agronomic traits of tow corn varieties as a second crop under drought stress and application of cycocel an experiment was conducted at Agricultural Research Station of Jahad-Keshavarsi of Khoy during summer growing season of 2005. Experimental design was a split-split plot based on RCBD with four replications. The factors consisted of irrigation as the main factor with three levels (irrigation after 70±5, 100±5 and 130±5 mm evaporation from class A pan), varieties 260 and 301 of corn as subfactor and application of different rates of cycocel (with and without application) as sub-subfactor. Results showed that drought stress reduced plant height, stem diameter, number of leaves and the leaf area index, biological yield and grain yield. Application of cycocel increased the stem diameter, biological yield and grain yield as compared with not application of cycocel. Generally, It can be concluded that irrigation after 70 mm evaporation and the application of cycocel can play major roles in increasing corn grain yield. Manuscript profile -
Open Access Article
378 - Evaluation of 20 Barley Genotypes under the Terminal Drought Condition
H. Tajalli S.G. Mousavi R. Baradaran M.H. Saberi E. ArazmjooTo study the response of barley genotypes to terminal drought stress, 20 promising barley genotypes were compared under two stress and non-stress conditions, in a split plot experiment based on randomized complete block design with three replications at the Agricultural MoreTo study the response of barley genotypes to terminal drought stress, 20 promising barley genotypes were compared under two stress and non-stress conditions, in a split plot experiment based on randomized complete block design with three replications at the Agricultural Research Center of Southern Khorasan during 2007-2008 growing season. Drought stress levels consist of control (complete irrigation) and irrigation up to the 50% heading stage. Results showed that skipping irrigation at 50% heading stage resulted in 14.64 reduction in seed yield and 8.12 percent in biological yield compared to control condition. Spike length, plant height and flag leaf area in drought condition decreased by 12.4, 7.65 and 24 percent against complete irrigation treatment. Also, irrigation up to the 50% heading caused increasing of chlorophyll index and cell membrane permeability and declining of relative water content of flag leaf. There weren’t any significant differences among barley genotypes in terms of biological yield but the highest and lowest grain yield achieved from genotype number 18 (5997.2 kg.ha-1) and genotype number 16 (3420.8 kg.ha-1) respectively. Cultivar number 5 and 13 had the highest rate of chlorophyll index, and also number 8 had the highest relative water content (80.7%) in flag leaf. Based on the results of this study, genotypes number 18 and 20 had higher yields in both normal and drought stress conditions. Manuscript profile -
Open Access Article
379 - Evaluation of Electrical Conductivity, Chlorophyll and Seed Yield of Wheat under Water Stress with Zeolite Application
‎ Mohammad Mirzakhani ‎Electrical conductivity of wheat cell sap and chlorophyll concentration of its leaves under drought stress and application of zeolite were evaluated in a split plot experiment, by using a RCBD with three at Arak Payam-Noor University in 2010. Treatments were four levels MoreElectrical conductivity of wheat cell sap and chlorophyll concentration of its leaves under drought stress and application of zeolite were evaluated in a split plot experiment, by using a RCBD with three at Arak Payam-Noor University in 2010. Treatments were four levels of water stress (I0= control irrigation, I1= irrigation at 85% of I0, I2= irrigation at 70% of I0, I3= irrigation at 55% of I0) assigned to the main plots and four levels of zeolite applications (Z0= without zeolite application, Z1= 3 t.ha-1, Z2= 6 t.ha-1, Z3= 9 t. ha-1) to the sub plots. Sub plots consisted of 4 rows of 5 m long spaced 50 cm apart and 20 plants per meter on the rows. In this study traits like peduncle length, awn length, number of spike per m-2, grain yield, electrical conductivity by using water with 50and 60oC were assessed. Results indicated that intraction effect of water stress and zeolit application on number of spike per m2, seed yield, and electrical conductivity at 50and 60oC water were significant. Mean comparisons of intraction effects showed that electrical conductivity of water with 50 and 60 oC (447 and 476 respectively) resulted in the least detrimental effect on cell membrane. Results also revealed that electrical conductivity at control irrigation (554 µs.cm-1) and application of 9 t.ha-1 of zeolit produced highest seed yield (4901 kg.ha-1) at wheat. Manuscript profile -
Open Access Article
380 - The Effect of Plant Growth Regulators and Different Explants on the Response of Tissue Culture and Cell Suspension Cultures of German Chamomile (Matricaria chamomilla L.)
L. Koohi, N. Zare R. Asghari-Zakaria P. SheikhZadeh-MosaddeghGerman chamomile (Matricaria chamomilla L.) is one of the most important medicinal plants that its essential oils used in different medicinal industries. In this study which was carried out in 2013 growing season at the Faculty of Agricultural Sciences of the University MoreGerman chamomile (Matricaria chamomilla L.) is one of the most important medicinal plants that its essential oils used in different medicinal industries. In this study which was carried out in 2013 growing season at the Faculty of Agricultural Sciences of the University of Mohaghegh Ardabili, the in vitro response of leaf and hypocotyl explants of German Chamomile in B5 medium supplemented with different levels of plant growth regulators including 2,4-D, naphthalene acetic acid (NAA), kinetin and 6-benzylaminopurine (BAP) were investigated in a factorial experiment based on completely randomized design (CRD).In addition, cell suspension cultures were established and characterized. Hypocotyl and leaf explants exhibited cell proliferation and produced callus within 1-2 weeks. The highest fresh weight of the callus (264.1 mg) was produced by leaf explants in the medium supplemented with 0.5 mg/l 2,4-D and 1 mg/l BAP. However, the leaf explants cultured on medium containing 1.5 mg/l 2,4-D showed the lowest cell proliferation and callus yield (40.42 mg). The highest percentage of root induction from leaf explants (58.73%) was observed on the medium containing 4 mg/l 2,4-D and 1 mg/l Kin, and from hypocotyl explants (48.61%) was observed on medium supplemented with 1.5 mg/l NAA. The 42.22% of calli derived from hypocotyl explants on B5 medium supplemented with 4 mg/l NAA and 3 mg/l BAP, were friable. Cell suspension cultures of German chamomile were established by transferring of hypocotyl-derived friable calli into the MS medium supplemented with 1.5 mg/l 2,4-D and 1 mg/l kinetin. The growth curve of cell proliferations started 4 days after culture and continued to grow until day 13th, where the cells entered stationary phase. Manuscript profile -
Open Access Article
381 - Effect of Water Deficit Stress and Seed Biopriming on the Physiological Indices and Antioxidant Activity of Tansey (Tanacetum persicum (Boiss.) Mozaff)
Fatemeh Bahmeh Abdolrazagh Danesh-Shahraki Zahra Lorigooini Mahdi GhobadiniaGrowing medicinal plants is important for utilizing their drug precursors, and preserving the genetic resources and diversity in the ecosystem. Tansyis one of the medicinal plants with its valuable therapeutic and antioxidant properties. To investigate the effect of pla MoreGrowing medicinal plants is important for utilizing their drug precursors, and preserving the genetic resources and diversity in the ecosystem. Tansyis one of the medicinal plants with its valuable therapeutic and antioxidant properties. To investigate the effect of plant growth promoting rhizobacteria on the physiological indices and antioxidant activity of tansyunder water deficit stress, a factorial pot experiment was conducted in a randomized complete block design at the Experimental Farm of Shahrekord University in 2016. The factors consisted at water deficit at three levels: full irrigation (control), 75% full irrigation and 50% full irrigation; and seed biopriming treatments at seven levels: non-bacterial inoculation (control), Azotobacter chroococcum, Bacillus amyloliquefaciens, Bacillus sp. strain A., Bacillus sp. strain B., Pseudomonas fluorescens and Pseudomonas putida. The results showed that bacterial inoculation treatments had a significant effect on all of the analyzed traits (p≤0.01). Azotobacter chroococcum inoculation had the most significant effect on chlorophyll a and carotenoids contents, biological yield, essential oil yield, and anthocyanin contents (0.020 µmol.ml-1). Bacillus sp. strain A showed a 2.5-fold increase in proline content compared to that of control, and Bacillus sp. strain B had the greatest effect on antioxidant activity (IC50 5.32 μg.ml-1). Moreover, Pseudomonas fluorescence increased the carotenoids content in 50% full irrigation treatment, and Pseudomonas putida had the highest effect on chlorophyll b and total chlorophyll contents, membrane stability, and leaf relative water content. The results revealed that the inoculation of Tansyseeds with Azotobacter and Pseudomonas bacteria, especially in deficit irrigation practices, is recommended to alleviate the adverse effects of water stress. Manuscript profile -
Open Access Article
382 - Effects of Potassium and Nitrogen Fertilizer Applications on Yield and Lodging of Rice (Oryza sativa L.) under Different Irrigation Regimes
Zahra Rabiei Naser Mohammadin Roshan Seyyed Mostafa Sadeghi Ebrahim Amiri HamidReza DoroudianTo evaluate the effects of potassium and nitrogen fertilizers on yield and lodging characteristics of Gilaneh rice cultivar under two irrigation regimes (permanent flooding and irrigation with to 10 days interval) a field split split plot experiment based on complete ra MoreTo evaluate the effects of potassium and nitrogen fertilizers on yield and lodging characteristics of Gilaneh rice cultivar under two irrigation regimes (permanent flooding and irrigation with to 10 days interval) a field split split plot experiment based on complete randomized block design with 3 replications in Rasht. Nitrogen and potassium fertilizers used were at the 0, 60 and 120 kg.ha-1 and 0, 80 and 160 kg.ha-1 as sub and sub sub factor, respectively. The results showed that the highest seed yield obtained about 3713 kg.ha-1 from permanent flooding with the application of 120 kg.ha-1 of nitrogen fertilizer and 80 kg.ha-1 of potassium fertilizer and the lowest yield 634 kg.ha-1 from 10 days irrigation interval, without using of potassium and nitrogen fertilizers. The 10-day irrigation interval reduced the bending moment of the internode 4 by 40%. With increasing the rate of potassium fertilizer, the lodging index of intermediate 4 decreased, which was due to the increase of cellulose content by 60% in this intermediate. Increasing nitrogen and potassium fertilizers decreased the lodging index at internodes 3 and 4. Irrigation at 10 days intervals decreased plant height, internode bending moment, cellulose and hemicellulose and seed yield It increased lodging index of intermediate, butincreasing fertilizer levels in both irrigation regimes had adverse effect on the traits under study. Manuscript profile -
Open Access Article
383 - Evaluation of Quality Traits of Forage Maize Cultivars as Affected by Different Plant Densities
Hamdollah Eskandari Abdollah Javanmard Fariborz ShekariMaize has an important role in livestock nutrition. Thus, improving its forage quality through agronomical managements seems to be of high importance. To evaluate quality traits of forage maize cultivars in response to plant densities, a factorial experiment based on RC MoreMaize has an important role in livestock nutrition. Thus, improving its forage quality through agronomical managements seems to be of high importance. To evaluate quality traits of forage maize cultivars in response to plant densities, a factorial experiment based on RCBD with three replications was carried out at the Research Station of Faculty of Agriculture, University of Maragheh during 2013-2014 growing season. The first factor was plant density with three levels (93000, 105000 and 119000 plant.ha-1) and the second factor was maize cultivars with five levels (Zola, Simon, NS, 540 and 370). Results of the experiment indicated that dry matter production was affected by the interaction of plant density and cultivar, where cultivar 540 produced the highest dry forage (980 g.m-2) by density of 119000 plant.h-1 and cultivar NS the lowest (933 g.m-2) dry forage by density of 93000 plant.m-2. However, all cultivars under study produced higher dry matter under higher plant densities. It was also observed that Zola cultivar, with 638 g.kg-1 of hemicellulose, had the lowest forage quality. Other cultivars were in the same statistical group. Phosphorous content of forage was in its highest value in 93000 plant density, while calcium content was not affected by plant density. Lower plant densities resulted in higher crude protein content. Cultivar no. 540 produced the highest crude protein yield (kg.ha-1) suggesting its superiority to the other cultivar. This cultivar can be recommended for growing in this region and other regions with same climatic conditions for producing high quality and quantity of maize forage production. Manuscript profile -
Open Access Article
384 - Potassium Humate as a Factor for Decreasing Deterioration of Wheat’s Seed
Ali Tamjid Reza ShahryariSeeds could be deteriorated during storage. Treatment of seeds by humic acid induces metabolic and biochemical changes which accelerate seed germination and its emergence. This research was carried out to evaluate the effect of seed pretreatment potassium humate on its MoreSeeds could be deteriorated during storage. Treatment of seeds by humic acid induces metabolic and biochemical changes which accelerate seed germination and its emergence. This research was carried out to evaluate the effect of seed pretreatment potassium humate on its deterioration under laboratory and greenhouse conditions. The experiment was carried out in a 5 × 4 × 3 factorial experiment using completely randomized design with three replications. Experimental factors were three levels of potassium humate (control, one and two parts per 1000 potassium humate), four wheat varieties (Shirodi, Darya, Morvarid and Chamran) and five heating times (zero, 48, 72, 96 and 144 hours). Results showed significant differences in simple effect of variety and effect of potassium humate × heating times for shoot length; simple effect of heating times and effect of potassium humate × varieties for germination percent; effect of potassium humate × varieties × heating times for radicle length, shoot dry weight, seminal roots dry weight and seedling dry weight. Pretreatment of seeds by using 2/1000 potassium humate produced × longest radicle roots in Shirodi, Darya, Morvarid and Chamran respectively with 72, 72, 144 and 96 hours heating times. The highest root dry weight was produced by 2/1000 potassium humate and 48 and 72 hours of heating times on Shirodi and Chamran, respectively. Application of 1/1000 of potassium humate produced the highest seedling dry weight in Shirodi, Darya and Morvarid with 48, 72 hours of heating times and without heating, respectively. Results also revealed that different varieties responded differently to potassium humate treatment at different heating times. It can be concluded that longer heating durations affected wheat characters at early growth stages and pretreatment of seeds by potassium humate can decrease seed deterioration. Manuscript profile -
Open Access Article
385 - Optimization of mixotrophic culture medium for maximum production of extracellular polysaccharides and bioactive compounds Aliinostoc oryzae cyanobacteria isolated from saline water of Golestan province
بهاره NowruziAbstractThe synthesis of extracellular polysaccharides in microorganisms, especially cyanobacteria, plays a major role in protecting the cell against many stresses in different habitats. In recent years, cyanobacterial strains belonging to the Nostocaceae family are of MoreAbstractThe synthesis of extracellular polysaccharides in microorganisms, especially cyanobacteria, plays a major role in protecting the cell against many stresses in different habitats. In recent years, cyanobacterial strains belonging to the Nostocaceae family are of interest as acceptable sources for polysaccharide production in liquid and solid suspension cultures. Therefore, in this research, the optimization of culture conditions for maximum production of extracellular polysaccharides and bioactive compounds under the influence of mixotrophic environment by filamentous cyanobacteria isolated from salt water has been studied. In the upcoming study, with the aim of investigating the effective factors in optimizing the production of exopolysaccharides and the effect of the mixotrophic environment, the cyanobacterium Aliinostoc oryzae strain was isolated from the salty waters of Golestan province, and after morphological and molecular identification, the amount of polysaccharide produced and its antimicrobial activity was investigated. The findings indicate that the amount of polysaccharide production from cyanobacteria depends on the conditions of the culture environment. The amount of polysaccharide production of cultures grown in nitrate concentration with concentrations of 0.04 and 0.06 g/ml and in light of 150 microns per square meter per second was significantly higher than the control. Antibiogram tests also showed that there was a significant difference in polysaccharide production in the presence of Staphylococcus aureus in nitrate culture. Investigations of the average production of extracellular polysaccharide extraction also showed a significant difference in different culture environments. Extracellular polysaccharide extracted from cyanobacteria has countless uses in the industry, including the pharmaceutical industry, food industry, and agriculture. Therefore, the optimization of the cyanobacterium culture conditions for the maximum production of polysaccharides appears. Since cyanobacterial exopolysaccharides are important from the point of view of biotechnology, it is important to pay attention to many other factors for maximum exopolysaccharide production in this genus of cyanobacteria. Manuscript profile -
Open Access Article
386 - Legal-jurisprudential analysis of civil liability resulting from construction on fault lines (taking into account Article 100 of the Municipal Law)
Sedigheh Riahi Rad Abdullah bahmanpouri mansor gharibpoorForce majeure, or in the interpretation of jurists, heavenly plague, is one of the issues raised in the law of different countries, including Iran, in the field of responsibility. There is no difference of opinion in this issue that the obligee can refer to these incide MoreForce majeure, or in the interpretation of jurists, heavenly plague, is one of the issues raised in the law of different countries, including Iran, in the field of responsibility. There is no difference of opinion in this issue that the obligee can refer to these incidents in order to acquit himself from the damages and as a legal effect, but where the human factor, due to the act or omission of the act, has a role in the occurrence of these incidents or in increasing the damages caused by them. Some differences can be observed. In French law, the committed party must consider the process of fulfilling the obligation by taking into account possible changes and developments. In Iranian law, in spite of being affected, the existence of a traditional view of force majeure (i.e. being heavenly and lack of responsibility) on the one hand, and the effect of the action or omission of the human factor in the occurrence of force majeure or the increase of damages caused by it, force majeure is considered to be a serious challenge in jurisprudence and He has faced legal issues. Issues such as awareness of the existing risk potential caused by an active fault, having the power of prediction, the ability to avoid an accident or damage, realizing the concept of a heavenly disaster and accepting its effects can be considered among these challenges. The present study, while examining the theory of force majeure in French law, Iranian law and jurisprudential sources, deals with the possibility of its application in Iran's legal system, taking into account general and specific jurisprudential evidence. Manuscript profile -
Open Access Article
387 - Contract Cancellation in the Shiite Jurisprudence and Law
Seyyed Ali Jabar Golbaghi MasoulehIn the Jurisprudence and law, there are different legal theories and institutions; They’ll organize a jurisprudence-law system altogether. Yet jurists violate most of these theories and institutions. Hence, according to comparative and simultaneous viewpoint of t MoreIn the Jurisprudence and law, there are different legal theories and institutions; They’ll organize a jurisprudence-law system altogether. Yet jurists violate most of these theories and institutions. Hence, according to comparative and simultaneous viewpoint of the Shiite jurisprudence and law, there are some unknown theories and institutions. In internal law, it is considered civil law of some foreign countries and in international law examination of some treaties concept introduces an institution for cancelling the contract. The present article aims to answer the following questions: -Is this institution of contract cancellation known for shiite’s jurisprudence and law? -What is the policy of shiite’s jurisprunce and law for contract cancellation of this institution? Manuscript profile -
Open Access Article
388 - Thermal stability optimization of the Soybean oil affected by thymus daenensis Celak essential oil by use of response surface methodology
M. Eghbalian Rad A. A. Sari A. Daraei GarmakhanyOxidative stability of oils and fats was affected by various factors such as oxygen, light, heat, metal ions and enzymes. The use of synthetic antioxidant for preventing oxidative deterioration, despite having high performance, due to the possibility of toxicity and car MoreOxidative stability of oils and fats was affected by various factors such as oxygen, light, heat, metal ions and enzymes. The use of synthetic antioxidant for preventing oxidative deterioration, despite having high performance, due to the possibility of toxicity and carcinogenicity, has been under question. The aim of this study was to optimize the thermal stability of soybean oil by the addition ofThymus daenensis Celakessential oil. In this study soybean oil was treated under various conditions of frying temperature (150, 170 and 190 °C), frying time (0, 6 and 12 h) and Thymus daenensis Celak essential oil concentrations (0, 400 and 800 ppm) and different quality attributes of samples such as the acid value, peroxide value, thiobarbituric acid, polar compounds, and conjugated diene value were studied. Results showed that Thymus essential oil due to containing different phenolic compounds increased the thermal stability of soybean oil significantly (p<0.05). The results of the acidic value, peroxide value, thiobarbituric acid, and polar compounds in fried oil samples for 12 hours at 190 °C showed that the addition of essential oil of thyme oil keeps the quality of fried oil after 12 hours frying at 190 °C. This study shows that essential oils can be a good alternative for synthetic antioxidants. Manuscript profile -
Open Access Article
389 - Effect of carboxymethyl cellulose and sodium alginate-based edible coating containing wild garlic (Allium ursinum L.) extract on the shelf-life of lactic cheese
S.M. Mousavi L. , Najafian M. FarsiNowadays, coating by natural materials is one of the novel food preservation methods with extensive applications. Cheese is a popular food, however, its high daily intake due to its high salt content may threaten the health of consumers. In this study, instead of stored MoreNowadays, coating by natural materials is one of the novel food preservation methods with extensive applications. Cheese is a popular food, however, its high daily intake due to its high salt content may threaten the health of consumers. In this study, instead of stored in brine, the novel method for cheese coating was used with the combination of 2% sodium alginate and 3% carboxymethyl cellulose with wild garlic extract at three concentrations of 0.5, 1 and 1.5%. Two uncoated cheese specimens (stored in or out of brine) were considered as the control groups. Physicochemical (pH, acidity and weight loss), microbial (thermophile, psychrophile, mold and yeast count), and sensory properties of the samples were investigated for 21 days at 4 °C. The results showed that during storage, pH decreased significantly (p < 0.05) while acidity, weight loss and microbial load increased. Coating with various ratios affected all of the sensory properties of the cheese samples. So that the highest score of total acceptance was related to the coating with 1.5% wild garlic extract. According to the results, edible coating based on sodium alginate and carboxymethyl cellulose, containing the wild garlic extract, can be used to increase the shelf life of cheese. Manuscript profile -
Open Access Article
390 - Effect of orange waste based nanobiocomposite film containing nettle essential oil and cellulose nanofiber on microbial and chemical characteristics of beef
S.E. Mousavi Kalajahi A. Alizadeh H. Hamishehkar H. Almasi N. AsefiBeef is considered the main source of dietary protein despite being perishable. In this regard, utilization of biodegradable films containing plant essential oils, as antimicrobial compounds, is one of the concepts to prolong the beef shelf life. Accordingly, this study MoreBeef is considered the main source of dietary protein despite being perishable. In this regard, utilization of biodegradable films containing plant essential oils, as antimicrobial compounds, is one of the concepts to prolong the beef shelf life. Accordingly, this study aimed to investigate the effect of the biodegradable film based on orange waste powder (OWP) containing nettle essential oil (NEO) and cellulose nanofiber (CNF) to increase the shelf life of the refrigerated beef samples stored for 12 days. As well, beef samples were divided into three groups of uncovered (control), wrapped with the OWP-based film without essential oil and nanofiber and wrapped with OWP-base film containing 3% NEO and 6% CNF and the microbial (aerobic mesophilic count, psychrophilic count, and coliform count) and chemical (pH, thiobarbituric acid and volatile nitrogen bases) properties were evaluated at regular intervals (0, 4, 8 and 12days). According to the results, the beef sample wrapped with OWP-base film containing 3% NEO and 6% CNF showed the lowest growth rate of the mentioned bacteria after 12 days of storage; Moreover, the samples covered by the film containing NEO and CNF had lower levels of pH, thiobarbituric acid and volatile nitrogen bases values compared to the other two samples at 12th day of storage. The results of this study indicate that wrapping beef samples with an OWP-based nanobiocomposite film containing 3% NEO and 6% CNF could remarkably prolong its shelf life in refrigerated conditions. TRANSLATE with x English Arabic Hebrew Polish Bulgarian Hindi Portuguese Catalan Hmong Daw Romanian Chinese Simplified Hungarian Russian Chinese Traditional Indonesian Slovak Czech Italian Slovenian Danish Japanese Spanish Dutch Klingon Swedish English Korean Thai Estonian Latvian Turkish Finnish Lithuanian Ukrainian French Malay Urdu German Maltese Vietnamese Greek Norwegian Welsh Haitian Creole Persian // TRANSLATE with COPY THE URL BELOW Back EMBED THE SNIPPET BELOW IN YOUR SITE Enable collaborative features and customize widget: Bing Webmaster Portal Back // TRANSLATE with x English Arabic Hebrew Polish Bulgarian Hindi Portuguese Catalan Hmong Daw Romanian Chinese Simplified Hungarian Russian Chinese Traditional Indonesian Slovak Czech Italian Slovenian Danish Japanese Spanish Dutch Klingon Swedish English Korean Thai Estonian Latvian Turkish Finnish Lithuanian Ukrainian French Malay Urdu German Maltese Vietnamese Greek Norwegian Welsh Haitian Creole Persian // TRANSLATE with COPY THE URL BELOW Back EMBED THE SNIPPET BELOW IN YOUR SITE Enable collaborative features and customize widget: Bing Webmaster Portal Back //TRANSLATE with xEnglishArabicHebrewPolishBulgarianHindiPortugueseCatalanHmong DawRomanianChinese SimplifiedHungarianRussianChinese TraditionalIndonesianSlovakCzechItalianSlovenianDanishJapaneseSpanishDutchKlingonSwedishEnglishKoreanThaiEstonianLatvianTurkishFinnishLithuanianUkrainianFrenchMalayUrduGermanMalteseVietnameseGreekNorwegianWelshHaitian CreolePersian // TRANSLATE with COPY THE URL BELOW BackEMBED THE SNIPPET BELOW IN YOUR SITE Enable collaborative features and customize widget: Bing Webmaster PortalBack// Manuscript profile -
Open Access Article
391 - The cytotoxic effect of Spirulina extract on gastric and prostate cancer cell lines
F. Khodaverdipour Ali SharifzadehThe AGS cell line contains gastric cancer cells, which are among the most common cancers in the world. The DU145 cell line also includes prostate cancer cells, the second leading cause of death in men after lung cancer. This study was designed to assess the cytotoxicity MoreThe AGS cell line contains gastric cancer cells, which are among the most common cancers in the world. The DU145 cell line also includes prostate cancer cells, the second leading cause of death in men after lung cancer. This study was designed to assess the cytotoxicity of spirulina extract on AGS and DU145 cell lines. In this in vitro trial, cell lines AGS and DU145 were used. Gastric and prostate cancer cell lines were prepared and cultured from the Iranian Center for Biological and Genetic Resources. The cells were divided into treatment and control groups. The effect of spirulina extract on the treated group was determined using the MTT method. According to MTT results, Spirulina extract has anti-cancer activity and more than 50% reduction in cell density against AGS and DU145 cell lines; While it did not show any significant effect on healthy cells (P< 0.05). The results of this study indicate that Spirulina extract has a good potential to control cancer cells. Manuscript profile -
Open Access Article
392 - Efficacy of microencapsulated nisin with sodium alginate and chitosan on biofilm formation in Listeria monocytogenes
S. Babakhani Farzaneh Hosseini P. Pakzad M. Bikhof TorbatiListeria monocytogenes is a foodborne pathogen the cause of listeriosis that has long-term survival due to biofilm formation. This study aimed to investigate the efficacy of nisin 102 IU/ml, encapsulated nisin with chitosan and sodium alginate on biofilm formation and c MoreListeria monocytogenes is a foodborne pathogen the cause of listeriosis that has long-term survival due to biofilm formation. This study aimed to investigate the efficacy of nisin 102 IU/ml, encapsulated nisin with chitosan and sodium alginate on biofilm formation and changing the expression level of genes related to biofilm formation L. monocytogenes ATCC 19115 (serotype 4b) was treated by nisin 102 IU/ml and microencapsulated nisin with chitosan and sodium alginate solutions. The effectiveness of nisin on cell survival was estimated by calculating the optical absorbance. After proving the presence of prfA, sigB, and agrA genes, the effect of 102 IU/ml nisin dilution on L. monocytogenes biofilm was investigated by the microtiter plate method. The expression level of prfA, sigB, and agrA genes was analyzed using real-time PCR methods (qRT-PCR). The inhibition rate of biofilm formation in L. monocytogenes by nisin 102 IU/ml was 57% at 37°C and pH 5.5. The maximum inhibition of biofilm formation was related to the simultaneous use of nisin 102 IU/ml with chitosan and sodium alginate at 37°C and pH 5.5. Microencapsulated nisin with chitosan and sodium alginate can increase its effectiveness in preventing the biofilm formation of L. monocytogenes to 76% (p<0.0001). Nisin 102 IU/ml decreased the expression level of prfA, sigB, and agrA by -2.313, -2.808, and -1.453-fold compared to the control (p<0.0001). Nisin only had significant inhibitory activity against L. monocytogenes biofilm. Microencapsulated nisin with chitosan and sodium alginate had high efficacy in preventing the biofilm formation of L. monocytogenes.Listeria monocytogenes is a foodborne pathogen the cause of listeriosis that has long-term survival due to biofilm formation. This study aimed to investigate the efficacy of nisin 102 IU/ml, encapsulated nisin with chitosan and sodium alginate on biofilm formation and changing the expression level of genes related to biofilm formation L. monocytogenes ATCC 19115 (serotype 4b) was treated by nisin 102 IU/ml and microencapsulated nisin with chitosan and sodium alginate solutions. The effectiveness of nisin on cell survival was estimated by calculating the optical absorbance. After proving the presence of prfA, sigB, and agrA genes, the effect of 102 IU/ml nisin dilution on L. monocytogenes biofilm was investigated by the microtiter plate method. The expression level of prfA, sigB, and agrA genes was analyzed using real-time PCR methods (qRT-PCR). The inhibition rate of biofilm formation in L. monocytogenes by nisin 102 IU/ml was 57% at 37°C and pH 5.5. The maximum inhibition of biofilm formation was related to the simultaneous use of nisin 102 IU/ml with chitosan and sodium alginate at 37°C and pH 5.5. Microencapsulated nisin with chitosan and sodium alginate can increase its effectiveness in preventing the biofilm formation of L. monocytogenes to 76% (p<0.0001). Nisin 102 IU/ml decreased the expression level of prfA, sigB, and agrA by -2.313, -2.808, and -1.453-fold compared to the control (p<0.0001). Nisin only had significant inhibitory activity against L. monocytogenes biofilm. Microencapsulated nisin with chitosan and sodium alginate had high efficacy in preventing the biofilm formation of L. monocytogenes. Manuscript profile -
Open Access Article
393 - Contamination rate of Brucella in raw sheep milk and the effects of cell-free supernatant of Lactobacillus acidophilus on its biofilm production
M. Parandakhteh M. Neyriz NaghadehiBrucellosis is one of the most important zoonotic bacterial diseases in humans and vertebrate animals. Lactic acid bacteria (LAB) and their production compounds have been proposed as potential biocontrol agents in biofilm formation. The present research aimed to determi MoreBrucellosis is one of the most important zoonotic bacterial diseases in humans and vertebrate animals. Lactic acid bacteria (LAB) and their production compounds have been proposed as potential biocontrol agents in biofilm formation. The present research aimed to determine the effects of cell-free supernatant (CFS) from Lactobacillus acidophilus on the biofilm production of Brucella isolates from raw sheep milk of Mahabad city (Iran). In this study, 100 sheep milk samples were randomly collected from different urban and rural areas of Mahabad. To isolate Brucella, the samples were cultured in Brucella broth and then streaked on Brucella agar with the selective supplement, and to identify the species of Brucella, related metabolic tests were performed. The biofilm production capability of the isolates, as well as the antibiofilm activity of the CFS, were evaluated by the microplate assay method. The results showed that out of 100 milk samples, 3 samples (3%) are contaminated with Brucella melitensis. Also, all three isolates were biofilm-formers. Two isolates were recognized as moderate and one isolate as a strong biofilm-former. Different concentrations of CFS reduced the biofilm production of isolates significantly (P˂ 0.01). Also, the concentration of 10% of CSF showed the highest antibiofilm activity. From the findings, it can be concluded that Brucella contamination in raw sheep milk in the Mahabad region is relatively high. There is a need for a full performance of Brucellosis screening and vaccination programs in livestock herds of the region. It can also be concluded that the CFS of L. acidophilus can remove Brucella biofilm. Therefore, L. acidophilus CFS as an antibiofilm compound can be proposed to control the growth of Brucella. Manuscript profile -
Open Access Article
394 - Retrospective study on the prevalence of Hydatid cyst, Fasciola species and Dicrocelium dendriticum in the liver of sheep and goats slaughtered in Saveh slaughterhouse, Markazi province and the estimation of economic losses caused by their liver condemnation from 2014 to 2020
Nasser HajipourSome zoonotic parasites such as Hydatid cyst, Fasciola species and Dicrocelium dendriticum cause death and economic losses in ruminants. The aim of this study was to investigate the prevalence rate of liver parasites in sheep and goats slaughtered in Saveh slaughterhous MoreSome zoonotic parasites such as Hydatid cyst, Fasciola species and Dicrocelium dendriticum cause death and economic losses in ruminants. The aim of this study was to investigate the prevalence rate of liver parasites in sheep and goats slaughtered in Saveh slaughterhouse and to estimate the economic losses caused by their condemnation. In a retrospective study, from April 2014 to April 2020, a total of 58,699 animals including 13,044 goats and 45,655 sheep were inspected in Saveh slaughterhouse for liver contamination with Hydatid cyst, Fasciola species and Dicrocelium dendriticum. The results showed that 72.85% of the animals were infected with parasites, 41.18%, 28.08%, and, 3.58% were infected with Dicrocelium dendriticum, Hydatid cyst, and Fasciola species, respectively. There was a statistically significant. The rate of infection with Dicrocelium dendriticum, Hydatid cyst and Fasciola species was 21.70%, 17.44%, and 1.33% in sheep and 16.48%, 10.64%, and 2.25% in goats, respectively. Statistically, the prevalence rate of liver infection with seasons was not significant except for 2015. The economic losses caused by the condemnation of the liver of slaughtered sheep and goats were estimated at 23,324,560,000 Rials ($241,330.16). With the high prevalence of parasitic diseases in small ruminants in the region and the economic losses caused by the condemnation of infected livers, and due to the fact that these diseases are zoonotic, it is crucial to use appropriate management methods to prevent or control the disease by competent authorities. Manuscript profile -
Open Access Article
395 - Reduction of acrylamide under different pretreatments in French fries (orginal reserch article)
Tala Rahbar Imani Leila Roufegari-NejadAcrylamide is formed in carbohydrate-rich foods during high temperature thermal processes. There are well-known biological effects from acute exposure to the high levels of acrylamide, so prevention or elimination of its formation is very important to achieve consumer s MoreAcrylamide is formed in carbohydrate-rich foods during high temperature thermal processes. There are well-known biological effects from acute exposure to the high levels of acrylamide, so prevention or elimination of its formation is very important to achieve consumer safety. Due to the ever-increasing consumption of potato and high amount of acrylamide in this product and particularly in French-fried potato, the aim of this study was investigating the effect of different pre-treatments effect [blanching in water, immersion in a calcium chloride solution and coating with carboxymethyl cellulose (CMC)] on reduction of acrylamide content as well as sensory properties of the fried potato. In this regard, the the potato samples were fried in 150°C for 7 min and acrylamide content was measured by gas chromatography with flame ionization detection (GC-FID). The results showed that pre-treatments, either alone or in combination, prevented the formation of acrylamide content varying 27% to 90%, which was statistically significant (p<005). The maximum reduction of acrylamide content was observed in the samples prepared by the combination of three pretreatments. Likewise, the sample blanched, immersed in 0.5% calcium chloride solution and coated with CMC showed the highest score of sensory properties. Consequently, the interaction of the studied pretreatments on the amount of acrylamide content in fried potatoes was significant (p<0.05). It seems that the combination of these pretreatments could possibly results in a healthy product. Manuscript profile -
Open Access Article
396 - Contamination rate of cow's raw milk with Brucella abortus in Parsabad region by Milk Ring Test
M.H Movassagh داور Panahei AzarBrucellosis is a zoonotic disease caused by gram-negative bacteria Brucella that are pathogenic for a wide variety of animals and human beings. Brucellosis, in particular, is easily transmitted via raw milk. Despite its control in many countries, it remains endemic in I MoreBrucellosis is a zoonotic disease caused by gram-negative bacteria Brucella that are pathogenic for a wide variety of animals and human beings. Brucellosis, in particular, is easily transmitted via raw milk. Despite its control in many countries, it remains endemic in Iran. The transmission of brucella from infected animals to humans occurs either by occupational contact or the consumption of contaminated animal products, especially milk, cream and fresh cheese. The purpose of this study was to evaluate the prevalence of cow raw milk contamination by Brucella abortus in Parsabad region. A total of 64 cow's raw milk samples were collected using cluster random sampling method from Parsabad milk collection centers from March to April 2009. Samples were monitored for Brucella abortus antibodies using Milk Ring Test. Based on the results of this study, the occurrence of Brucella abortus was estimated as 37/5% in Parsabad region. It was concluded that the presence of Brucella abortus in bulk raw milks of Parsabad region is very probable. Therefore, it is necessary to determine the prevalence of Brucella abortus in bulk raw milks using the microbiological assays. Manuscript profile -
Open Access Article
397 - The effect of intensive endurance exercise and probiotic yogurt consumption, on aerobic, anaerobic, white blood cells, lymphocytes, monocytes and neutrophils in young Football players
G. R. Jahani ghaeh ghashlagh K. Dehghanpour A. KhaledanThe Aim of this study was to investigate the effect of intensive endurance exercise and probiotic supplementation on aerobic, anaerobic power, white blood cell (WBC), lymphocytes (LYM), monocytes (MON) and neutrophils (NUT) in young Football players. This study was semi MoreThe Aim of this study was to investigate the effect of intensive endurance exercise and probiotic supplementation on aerobic, anaerobic power, white blood cell (WBC), lymphocytes (LYM), monocytes (MON) and neutrophils (NUT) in young Football players. This study was semi-experimental, 36 young Football players with height 172± 0.77 cm, weight 66.76±5.87 kg and BMI 21.27±2.09 kg/m2, randomly assigned into control (n=18) and experimental (n=18) groups. Medical examinations and physical fitness tests were performed before and after training done. They performed a training program for 8 weeks, three times a week, every session 90 to 120 min. Experiment group consumed 400 ml probiotic yoghurt one hour before every session of training. Both groups trained aerobic exercise with 60-75% and anaerobic with 80-100% (MHR). To determine the variables blood samples were taken four times. Initially, before the training program, there were not significantly different amounts of variables. After 8 weeks in the experiment group, the levels of lymphocytes and neutrophils significantly increased. Any report about URTI infection was not observed. Eight weeks training improved the aerobic and anaerobic power, meanwhile reduce the incidence of URTI after ingestion of probiotic yoghurt. As a conclusion, it is recommended to the athletes to consume probiotic supplement before intensive endurance exercises. Manuscript profile -
Open Access Article
398 - The effects of Tilia (Tilia plathyphyllos) extract on gene expression of caspase 3 and caspase 9 in canine mammary gland cancer cell line (CF41.Mg)
Zohreh Mostahsan Pejhman MortazaviMammary gland tumors arethe most common type of cancer in dogs and cats after skin tumors. Any disorder in the process of apoptosis causes the growth of cancer cells. Caspases 3 and 9 play an important role in the process of apoptosis as initiator and executioner caspas MoreMammary gland tumors arethe most common type of cancer in dogs and cats after skin tumors. Any disorder in the process of apoptosis causes the growth of cancer cells. Caspases 3 and 9 play an important role in the process of apoptosis as initiator and executioner caspases. This study was conducted to investigate the effect of Tilia (Tilia plathyphyllos) extract on gene expression of caspase 3 and caspase 9 in canine mammary gland cancer cell line. Canine mammary gland tumor cells (CF41.Mg) were passaged in the presence of 5, 10, 25, 50 and 100 mg/ml of Tilia extract for 24, 48 and 72 hours. Microculture tetrajolium test (MTT) was used after the passage to assay the number of live cells. To understand the mechanisms involved in induction of cell death at previously mentioned intervals, RNA was extracted and cDNA synthetizedand the rate of gene expression of caspase 3 and 9 was evaluated using specific primers with RT-PCR. According to the result, maximum anti-tumor activity of this extract was observed after 48 hours with the dose of 25 mg/ml. RT-PCR results indicated gene expression of caspase 3 and 9 after 24, 48 and 72 hours in the treated samples. The highest extent of gene expression was observed at 10 and 100 mg/ml of extract for caspase 3 and 10 mg/ml of extract for caspase 9. The results of the present study confirmed the inhibitory effects of Tilia extract on growth of canine mammary gland tumor cell line. Manuscript profile -
Open Access Article
399 - Effects of Apium graveolens extract on serum calcium and oxalate in ethylene glycol- induced kidney injury in male Wistar rats
Parisa Mehrparvar Akram Eidi Pejman Mortazavi Shahrbanoo OryanCelery (Apium graveolens) is a biennial plant, belonging to family Apiaceae. Various parts of celeryare used in hepatic and spleen disorders, brain disorders, body pain, and sleep disturbances. The present study was planned to investigate the effect of celery ethanolic MoreCelery (Apium graveolens) is a biennial plant, belonging to family Apiaceae. Various parts of celeryare used in hepatic and spleen disorders, brain disorders, body pain, and sleep disturbances. The present study was planned to investigate the effect of celery ethanolic extract on ethylene glycol induced kidney injury in male Wistar rats. Urolithiasis was induced in hyperoxaluric rat model by giving 0.75% ethylene glycol for 28 days. Animals were divided into 8 groups (n=6) including normal control, urolithiatic control (0.75% ethylene glycol in their drinking water), normal rats receiving celery extract at doses of 50, 100 and 200 mg/kg and urolithiatic rats receiving celery extract at doses of 50, 100 and 200 mg/kg intragastrically. At the end of the experiment (28 days), blood samples were collected by cardiac puncture and serum calcium and oxalate was analyzed. Statistical analysis was performed by one-way analysis of variance followed by Tukey post hoc test (p<0.05). Significant elevation of serum oxalate and reduction of serum calcium was observed in urolithiatic control rats compared with the normal control rats. Administration of celery extract at a dose of 200 mg/kg produced significant elevation in serum calcium and reduction in serum oxalate in urolithiatic rats. Thus, celery extract could ameliorate urolithiasis induced by ethylene glycol. Manuscript profile -
Open Access Article
400 - Evaluation of the effect of local massage on milk production and udder immunity of dairy cows
Ehsan Emamjome Kianoush Khashayar Saeed Azimpour majid fartashvand Hadi PourtaghiMilk somatic cell count (SCC) is a common method of assessing the quality of milk produced and the status of mastitis. Massage improves the level of cellular immunity. This study aimed to evaluate the effect of massage on udder immune system according to SCC and milk pr MoreMilk somatic cell count (SCC) is a common method of assessing the quality of milk produced and the status of mastitis. Massage improves the level of cellular immunity. This study aimed to evaluate the effect of massage on udder immune system according to SCC and milk production. For this purpose, 14 high-producing cows aged about 3 years which had given birth three months ago were chosen. The cows were then divided into control and treatment groups. The treatment group received udder massage twice a day for four weeks. During the investigation, weekly SCC was conducted. The rate of milk production was also recorded on day zero and in the sixth week which was the last week of massaging in the treatment group. The results indicated a dramatic and non-significant (p < /em>>0.05) increase of SCC and a significant decrease of milk production in the treatment group. There was no significant difference in SCC between the two groups except in the third week and no significant correlation was observed between milk production and SCC. But the difference in average milk production between the two groups at the end of the sixth week was significant (p < /em><0.05) in comparison to the first week. The results of the present study indicated that long-term massage is stressful and decreases the level of udder immunity and subsequent milk production. Manuscript profile -
Open Access Article
401 - Alterations in acute phase proteins, hemogram and electrophoretic pattern of equine serum proteins following change of diet from forage to forage mixed with concentrate
Rouhoullah Karampour Mohammad Razi Jalali mohammad rahim haji hajikalaei Alireza Ghadrdan mashhadiDespite extensive studies on the relationship between diet type and its effect on equine biochemical factors, little is known about horse serum and plasma proteins following changes in diet from forage to forage mixed with concentrate. Acute phase proteins are a group o MoreDespite extensive studies on the relationship between diet type and its effect on equine biochemical factors, little is known about horse serum and plasma proteins following changes in diet from forage to forage mixed with concentrate. Acute phase proteins are a group of serum proteins whose concentrations increase in response to infections, inflammation, trauma, and neoplasia. Therefore, in the present study, we evaluated the serum levels of serum biomarkers, fibrinogen and total protein concentration along with the nutritional behavior of horses during diet change. For this purpose, two types of diets, including forage (first treatment) and mixture of forage with concentrate (second treatment) were used for each horse for fifteen consecutive days. Complete blood cell counts as well as serum levels of fibrinogen, haptoglobin and amyloid type A were measured before and after dietary changes. Serum fibrinogen, haptoglobin and amyloid A levels were significantly increased in horses of the second treatment group compared to horses in the first treatment group (p<0.05). There was also a statistically significant difference in the complete blood cell count due to the change of diet from forage to forage mixed with concentrate (p<0.05). It seems that changes in the natural flora of the horse's digestive tract following a change in diet can protect the animal's body against acute inflammatory and traumatic injuries. Manuscript profile -
Open Access Article
402 - Effect of magnesium oxide nanoparticles on varicocele-induced testicular damage in male Wistar rats
Masoumeh Tolu Ghamari Akram Eidi Pejman Mortazavi Ahmad AsghariVaricocele is a pathological dilation of the venous network of the spermatic cord and considering that magnesium oxide nanoparticles play a key role in various physiological functions, the aim of this study was to evaluate the performance of nanoparticles on sperm chara MoreVaricocele is a pathological dilation of the venous network of the spermatic cord and considering that magnesium oxide nanoparticles play a key role in various physiological functions, the aim of this study was to evaluate the performance of nanoparticles on sperm characteristics affected by experimental varicocele. A total of 54 male Wistar rats were randomly divided into 9 equal groups including healthy control group (untouched animals), sham-operated group (underwent sham surgery), three healthy experimental groups (animals in these groups received magnesium oxide nanoparticles at doses of 1.25, 2.5 and 5 mg/kg respectively by gavage for 6 weeks), varicocele control group (varicocele was induced by renal vein ligation) and three experimental varicocele groups (in addition to varicocele induction, magnesium oxide nanoparticles were given at doses of 1.25, 2.5 and 5 mg/kg respectively by gavage for 6 weeks). At the end of the 6th week, the abdomen was opened and semen samples were collected from the tail of the epididymis to determine the indices of concentration, survival and motility of sperm and the data were statistically analyzed (p<0.05). The results showed that magnesium oxide nanoparticles were able to significantly increase the concentration, viability, progressive, moderate and non-progressive movements of sperm compared to the varicocele group (p<0.001) and also caused a significant decrease (p<0.001) in the number of non-moving sperms in the varicocele experimental groups. Therefore, magnesium oxide nanoparticles may possibly reduce the destructive effects of varicocele due to their antioxidant activity and be effective in its treatment by improving sperm properties during varicocele. Manuscript profile -
Open Access Article
403 - media conditioning on the antioxidant and histomorphometry of testis following caffeine consumption in adult male rat
Davoud Rahimi Jabbar Bashiri Alireza NoorAzar رقیه Pouzesh Jadidi Daryoush MohajeriConsidering the consumption of caffeine as a supplement favored by theathletes and the proof of its long-term abuse effects on male fertility, the purpose of this study was to investigate the effect of moderate aerobic training combined with the conditioning of Sertoli MoreConsidering the consumption of caffeine as a supplement favored by theathletes and the proof of its long-term abuse effects on male fertility, the purpose of this study was to investigate the effect of moderate aerobic training combined with the conditioning of Sertoli cell media in testicular damage caused by caffeine consumption.For this purpose,30male Wistar rats were tested in5groups.For4weeks, the groups received caffeine at a dose of200 mg/kg orally and group1received of distilled water.42days after that, the conditioned media of Sertoli cells was injected into the efferent ducts of the rats in the treatment group.After8 weeks, mice were sampled.Tissue samples were studied by histomorphometry andSOD,,GPX, TACand MDA.The group under the influence of caffeine compared to the healthy group, significantly(p<0.01).had lower values of seminiferous tubule diameter, epithelium height, interstitial thickness,TAC, SODandGPXand higher values ofMDA. Respectively, the three groups affected by caffeine along with exercise treatment, treatment with media conditioning and exercise along with media conditioning compared to the group affected with caffeine, have higher values of seminiferous tubule diameter, epithelium height, interstitial thickness,TAC, SODandGPX,and MDA values were lower.In the treatment group with media conditioning and exercise, there was a significant difference in the amount of decrease and increase in the mentioned parameters compared to the other two treatment groups (p<0.05).The results of the present study showed that the use of Sertoli cell media conditioning and aerobic exercise at the same time, with synergistic effects, improves the antioxidant defense indices and reduces the harmful effects of caffeine in the testicular tissue of rats.. Manuscript profile -
Open Access Article
404 - A serological survey of ovine and caprine brucellosis in slaughterhouses of East Azerbaijan province during 2004
Afshin Javadi قهرمان Akrami Nojadeh M.R Javadi مهدی Ahmad KhanliBrucellosis is a zoonotic disease which could be transmitted from animals to humans by ingestion of contaminated raw milk, dairy products or contact with meat or raw animal products. Thus, determination of brucella contaminated sheep and goat meat due to the risk of bru MoreBrucellosis is a zoonotic disease which could be transmitted from animals to humans by ingestion of contaminated raw milk, dairy products or contact with meat or raw animal products. Thus, determination of brucella contaminated sheep and goat meat due to the risk of brucellosis transmission to human was the purpose of the present study. For this study, blood samples were collected directly during slaughtering from 441 female sheep and 300 female goats with an age of over a year slaughtered at abattoirs of East Azarbaijan province. At first, positive samples were separated by Rose Bengal test and then quantited with Wright and 2-ME tests. All the results were compared with standard veterinary tables and the data were analyzed using the Chi-Square test. According to this research, the prevalence rate of brucellosis among sheep and goats was 4.53% and 5.33% respectively. The prevalence rate of sheep and goat brucellosis in Shabestar city was significantly higher than other cities (P<0.01) but there was no significant difference between sheep and goat brucellosis. Manuscript profile -
Open Access Article
405 - Histopathological evaluation of the effect of Sulfamide+Trimethoprim administration on renal tissue in broiler chickens
یوسف Doustar عادل Feizi داریوش Mohajeri M.H Khayat-Nouri M.H Mohammad pour, M.HAdministration of sulfonamides adversely affects renal tissue in human beings and animals. The aim of the present study was to evaluate the histopathological changes in renal tissue of broiler chickens following administration of Sulfamide+Trimethoprim. In this study, 2 MoreAdministration of sulfonamides adversely affects renal tissue in human beings and animals. The aim of the present study was to evaluate the histopathological changes in renal tissue of broiler chickens following administration of Sulfamide+Trimethoprim. In this study, 240 healthy 3 weeks old broiler chickens were randomly assigned to two equal groups. In the treatment groups, sulfonamide +Trimethoprim were administered at a dose of 20ml in 800lit of drinking water for 3 days while no drag was administered in the control group. After 72 hours, tissue samples were collected from the kidneys of the broiler chickens and 5µm thick sections were prepared from specimens fixed in 10% buffered formalin and stained with hematoxylin and eosin and the TUNEL technique. Histopathological examination of the renal tissue in the treatment group indicated the presence of necrosis and apoptosis in renal tubular epithelial cells, congestion, hemorrhage and glomerolopathy. The difference between the treatment and control groups in the severity of renal pathological changes was significant (p<0.001). The result of this study indicates that the drag Sulfamide+Trimethoprim is capable of causing renal tissue damages through induction of apoptosis and necrosis. Manuscript profile -
Open Access Article
406 - Microscopic study of the histogenesis of ependymal cells located in the lateral ventricles of ovine fetal brain
سیدسجاد Hejazi رسول Shahruz محمد Manafi یوسف AngouriThe aim of this study is the determination of the morphogenesis of ependymal tissue cells during the fetal period to beginning of birth in lateral ventricles of sheep`s brain. The study was in the form of descriptive observation conducted on 50 sheep fetuses which were MoreThe aim of this study is the determination of the morphogenesis of ependymal tissue cells during the fetal period to beginning of birth in lateral ventricles of sheep`s brain. The study was in the form of descriptive observation conducted on 50 sheep fetuses which were collected randomly. The length of the collected fetuses were measured and their age calculated by the formula x=2.1 (Y+17). Following fixation of the fetal brains in 10% buffered formalin they were separated from the skull and sectioned transversely caudal to the optic chiasma in order to obtain samples from the lateral ventricles. The samples were studied histologically after the histotechnique and staining procedures. Microscopically the group of neuroblastic cells surrounding the lateral ventricles consisted of ventricular and subventricular zones with intense mitotic activity in the ventricular zone. The ependymal epithelial tissue changed from pseudostratified to simple cuboidal during development. The thickness and mitotic activity of the neuroblastic mass at different parts of the lateral ventricular wall had a direct relationship with development of other parts of the brain. There was also a direct relationship between the retention of cilia in ependymal cells and the extension of the choroids plexus. Manuscript profile -
Open Access Article
407 - Isolation, culture expansion and characterization of canine bone marrow derived mesenchymal stem cells
داود Kazemi کریم Shams Asenjan نیما Dehdilani حامد Parsa A.A Movassagh Pour Akbari پروین AkbarzadehThe purpose of the present study was to isolate, culture expand and characterize canine bone marrow derived mesenchymal stem cells. Bone marrow aspirates of 15 adult male dogs were collected to this end and their mononuclear cells isolated by centrifugation and cultured MoreThe purpose of the present study was to isolate, culture expand and characterize canine bone marrow derived mesenchymal stem cells. Bone marrow aspirates of 15 adult male dogs were collected to this end and their mononuclear cells isolated by centrifugation and cultured in standard media. The adherent cells were isolated and their mesenchymal origin was confirmed at 3rd passage by cellular morphology, expression of surface antigens and differentiation to osteogenic and adipogenic lineage. After 4 days, spindle shaped fibroblast like cells which were apparently bone marrow derived mesenchymal stem cells appeared in culture medium and their numbers increased over time. The cells reached 3rd passage with over 75% confluent after a mean of 22.89±5.75 days. Flow cytometric analysis revealed that the cells negatively expressed CD34 and CD45 antigens while positively expressing CD44 and CD105 antigens. Differentiation into osteogenic and adipogenic lineage had taken place after one month culture in induction medium. VDR, COL1A1, BGLAP and SPARC gene expression indicated that mesenchymal stem cells isolated from canine bone marrow had differentiated into osteogenic lineage. These findings can form the basis of any forthcoming clinical studies involving the use of canine mesenchymal stem cells particularly in the field of bone and cartilage regeneration. Manuscript profile -
Open Access Article
408 - Changes of rabbits’ red blood cell counts in experimentally-induced pulmonary embolism confirmed using scintigraphy
gholamreza assadnassab The purpose of this study was to determine the changes in red blood cell counts after experimentally induced pulmonary embolism in rabbits which was confirmed by scintigraphy. Red blood cell count is important in health and diseases because these cells tran More The purpose of this study was to determine the changes in red blood cell counts after experimentally induced pulmonary embolism in rabbits which was confirmed by scintigraphy. Red blood cell count is important in health and diseases because these cells transfer oxygen from lung to tissues. One of the practical methods for diagnosis of pulmonary embolism is scintigraphy. Twelve adult male rabbits were selected. A group of six rabbits was used as control. In another group of six rabbits pulmonary embolism was experimentally induced by injection of autologous blood clots through right jugular vein. Pulmonary embolisms were confirmed by scintigraphy operations. At 0, 30, 60 min, 24, 48 and 72 hours after induced pulmonary embolism, blood samples were collected from rabbits of both groups and the red blood cell counts were determined. The technetium was milked from molybdenum- technetium generator and then added to macroaggregated albumin (MAA) kit. In all rabbits, 1.5 mCi of prepared 99mTC–MAA was injected into the marginal ear vein. In control group, 1ml of normal saline was injected via the margin ear vein. In this study, increases in red blood cell counts of the diseased rabbits were observed in the first and second days. These counts returned to normal status in the third day. These changes may reflect the performance of the body's immune system and response of physical reflexes to reduce the complications of pulmonary embolism. Therefore it is recommended that in patients with pulmonary embolism, more attention to red blood cell counts is required due to their specific performance along with other measurements. Manuscript profile -
Open Access Article
409 - Study counts of white blood cell counts following injection of technetium-99m in the cat
gholamreza assadnassab shahram dabirioskouie seyyedali shabestariasl babak mahmoudian aytak assadnassabThe purpose of this study was count the white blood cells following injection of technetium-99m in the cat. Radioactive materials can be used in diagnostic and therapeutic procedures. Technetium is used in most labeling and nuclear medicine diagnostic studies because of MoreThe purpose of this study was count the white blood cells following injection of technetium-99m in the cat. Radioactive materials can be used in diagnostic and therapeutic procedures. Technetium is used in most labeling and nuclear medicine diagnostic studies because of its favorable conditions in the body. In this study, injection of technetium-99m was used to evaluate the possible changes in the number of white blood cells because these cells are used in labeling and tracing of radioactive materials in the body and their alterations are important in many operations. In the present study, technetium was milked from Molybdenum to technetium generator and it was rapidly injected in 1.5 mCi into six cats through the femoral vein. A group of four other cats were used as controls after injection of saline. At 0, 30, 60 minutes, 24 and 48 hours after injection, blood samples were collected from all cats and the number of white blood cells were counted. This study did not show any significant changes in the amount of white blood cells in the two groups. Thus, the results of this study outlines the advantage of using technetium-99m as a radio-drug in treatment and diagnostic procedures. Manuscript profile -
Open Access Article
410 - Ultrastructural study of primordial germ cells, oogonia and oocytes in goat fetus
S.M Banan Khojasteh رضا Ranjbar نعیم Alboghobeish A.A Farshid محبوبه Salehi According to morphological evidences, primordial germ cells (PGCs) are derived from the caudal endoderm of the yolk sac and migrate to embryonic gonads. After entering the gonads, first they differentiate to oogonia and then to oocytes. In the presen More According to morphological evidences, primordial germ cells (PGCs) are derived from the caudal endoderm of the yolk sac and migrate to embryonic gonads. After entering the gonads, first they differentiate to oogonia and then to oocytes. In the present study, ultrastructure of PGCs, oogonia and oocytes has been examined. Tissue samples were collected from posterior parts of the yolk sacs of fetuses in the early stages of development (with age of less than 1 month), and also gonads of fetuses at later developmental stages (with age of more than 1 month). Samples were studied using transmission electron microscopy after fixation, washing with buffers, dehydration, embedding and staining with uranyl acetate and lead citrate. The Results indicated that PGCs were large with oval to spherical nuclei, reticular chromatin with nucleoli, and there were plenty of glycogen and also different organelles in their cytoplasm. Oogonia showed active mitotic divisions. These cells had regular plasma membranes and were observed as cellular clusters with spherical shape, euchromatin nucleus containing one or more nucleoli, round mitochondria and vacuoles with different sizes in cytoplasm. Oocytes had larger sizes in comparison with oogonia but didn't show cellular clusters. Manuscript profile -
Open Access Article
411 - Effects of somatic cell count in subclinical mastitis on raw milk quality in dairy farms of Khuzestan province
mohammad Hossieni nejad zohreh Mashak Mastitis is an infectious disease that is spread in livestock and can cause cattle mortality. Generally a cow with mastitis has a 15 per cent decrease in milk production. In addition, losses from changes in some components of milk should also be considered. More Mastitis is an infectious disease that is spread in livestock and can cause cattle mortality. Generally a cow with mastitis has a 15 per cent decrease in milk production. In addition, losses from changes in some components of milk should also be considered. Any change in milk properties can be severe hazard for milk producers, dairy factories and consumers. In this study, the effect of somatic cell count on row milk quality of cows affected by subclinical mastitis was studied. For this purpose 240 milk samples were collected from dairy farms with subclinical mastitis (traditional and industrial) of Khuzestan province in 2014 and their somatic cell count, protein and lipid contact and acidity determined. The mean±SD for somatic cells, acidity, protein and fat were 3.20×105±1.37×105 SCC/ml, 14.50±0.62 D°, 3.12±0.06% and 3.23±0.14% respectively. After statistical analysis, reverse correlation were found between somatic cell count with milk fat and protein. However, direct correlation was observed between range of milk fat and protein (p>0.01). Furthermore the results indicated that the range of acidity in spring and winter, protein and fat in winter and somatic cell in summer and autumn were more than the other seasons. According to statistical analysis, protein percent of milk samples in industrial farms were higher than traditional farms although the range of somatic cells was higher for traditional milk samples ‏)p>0.05) According to the result, it seems that the somatic cell count of milk influences raw milk fat and protein content and acidity. Manuscript profile -
Open Access Article
412 - Report of chewing louse, infestation Philopterus ocellatus (Mallophaga: Ischnocera) from Black Crows (Corvus corone) in Miandoab region, West Azerbaijan province in 2010
abbas imanibaran During summer 2010, in order to investigate ectoparasites infestation, a total of 12 carrion crows (Corvus corone) were caught from Miandoab region. Thereafter, a total of 32 lice (19 female, 13 male) were collected on feathers of seven infested crows and d More During summer 2010, in order to investigate ectoparasites infestation, a total of 12 carrion crows (Corvus corone) were caught from Miandoab region. Thereafter, a total of 32 lice (19 female, 13 male) were collected on feathers of seven infested crows and dehydrated, cleared and mounted. Measurements of different body parts of mounted specimens were made. The identification of lice indicated that they belong to Philopterus ocellatus. Morphologically, body is elongated, brown in color, measured about 2-3 mm in length and ≤1 mm in width. Head is triangular in shape, measured 0.7-0.8 mm in length and 0.3-0.4 mm in width, expanded in the caudal region. Five-segmented, very short antennae with initial long segment lie posterior to conus. It has large buccal cavity having 3-4 pairs of very prominent lateral sensory hairs as pre and postconal setae in which postconal setae are longer than preconal setae. The legs are short ending in a stout single claw. Third pair of legs is relatively sturdy and longer than two other pairs. The abdomen has 9 abdominal segments with abundant setae and quite evident respiratory pores on marginal plates. In females, the ovipositor and in males genitalia with characterizations related to reported species are clearly seen. According to the obtained results, the infestation rates varied from 3 lice in lowest to 8 lice in highest rate. The prevalence of infestation was determinated as 58.33%. Regarding the lack of comprehensive research on bird lice infestation in this study area, it is essential to conduct further extensive studies on various aspects of lice infestation. Manuscript profile -
Open Access Article
413 - Alterations in body weight and blood glucose level of female hamsters exposed to electromagnetic fields of cell phones
A.R Lotfi حبیب Aghdam ShahryarMicrowaves such as those emitted from electromagnetic fields of cell phones can penetrate live tissues and results in changes of ion distribution in membranes and may interfere with metabolic reactions. Considering the increasing use of cell phones, in the present study MoreMicrowaves such as those emitted from electromagnetic fields of cell phones can penetrate live tissues and results in changes of ion distribution in membranes and may interfere with metabolic reactions. Considering the increasing use of cell phones, in the present study the effects of 900 MHz electromagnetic fields of cell phones on body weight and blood glucose concentration of adult hamsters were investigated. Seventy two female hamsters were randomly allocated into three experimental groups. Group 1 served as the control group without the effect of electromagnetic field. Group 2 was exposed to electromagnetic field emitted by cell phones for 10 days (short term) and group 3 for 50 day (long term). In the latter groups, the exposure was 1 hour per day. At the end of the experimental period, the animals were weighed and blood glucose concentrations were determined by obtaining blood samples from 8 randomly selected hamsters in each group. The blood glucose level was significantly higher in long-term exposed group in comparison with the control and short-term exposed groups (175, 11.6 and 107 mg/dl, respectively) (p<0.01). Also, long-term exposed group had more weight gain compared with the control and short-term exposed groups (114.5, 11.6 and 101 gr, respectively) (p<0.01). In this study, long term (50 day period) exposure to electromagnetic fields emitted by cell phones resulted in significant increase in body weight and blood glucose levels of hamsters. Therefore, in long term, exposure to these fields could increase blood glucose levels and body weight of rodents. Manuscript profile -
Open Access Article
414 - The comparative effect of prebiotic, growth promoter antibiotic, probiotic, yeast cell wall and acid fire on broiler chickens performance
افشین Zakeri مهدی Taghi Nejad Roudbaneh آیدین Azizpour وحید HajiabalooIn this study 600 Cobb 500 broiler chickens were divided in six similar groups (A, B, C, D, E&F) with 100 chickens in each group (with four replicates of 25 chickens in each group). 100 g/ton growth promoter antibiotic in experimental group (B), 100 g/ton Prebiotic MoreIn this study 600 Cobb 500 broiler chickens were divided in six similar groups (A, B, C, D, E&F) with 100 chickens in each group (with four replicates of 25 chickens in each group). 100 g/ton growth promoter antibiotic in experimental group (B), 100 g/ton Prebiotic in experimental group (C), 800 g/ton Acid fires in experimental group (D), 1 kg/ton MOS in experimental group (E) and 4 kg/ton Yeast cell wall in experimental group (F) were added to the basic diets however the control group (A) chickens were fed only with the basic diet. Every week 100 chickens from each group were selected randomly and productive parameters such as weight gain, FCR, EEF, mortality, feed intake (FI) were calculated. On days 9, 17 and 25 of growth (1 day before and 7, 14 days after first Newcastle B1 vaccination), from each groups, each time 20 chickens were chosen randomly and serum antibody titres of these chickens were measured against Newcastle vaccine by HI test. The results obtained from statistical analysis indicated that using natural growth promoting substances not only increases humoral immunity but it also leads to improvement of productive parameters (p<0.05). Manuscript profile -
Open Access Article
415 - Evaluation of the effect of adding different levels of n-3 fatty acids to the Bioxcell® extender on freezing ability of goat semen
مهدی Ansari آرمین Towhidi محمد Moradi ShahrbabakThe objective of this study was to investigate adding different levels of a n-3 fatty acid source to the Bioxcell® extender on freezing ability of goat semen. Six mature Mahabadi bucks were selected and semen was collected using an artificial vagina. Semen samples w MoreThe objective of this study was to investigate adding different levels of a n-3 fatty acid source to the Bioxcell® extender on freezing ability of goat semen. Six mature Mahabadi bucks were selected and semen was collected using an artificial vagina. Semen samples were pooled together and divided into four equal groups, after evaluating for qualitative characteristics. Treatment groups were supplemented by 0, 0.1, 1 and10 ng/ml levels of n-3 fatty acid, respectively. The rates of motility, progressive motility, viability and sperm abnormality were evaluated and recovery rate was calculated. Data were analyzed using proc GLM of SAS. Percentage of motility and recovery rate were significantly higher in 10 ng/ml group than the other groups. Percentage of progressive motility was significantly higher in 10 and 0.1ng/ml than the other groups. Percentage of viability was significantly lower in 1ng/ml group than the other groups. Percentage of abnormality was not significant between the levels of n-3 fatty acid. The results indicated that adding of 10 ng/ml n-3 fatty acids to extender could improve freezing ability of goat semen. Manuscript profile -
Open Access Article
416 - Preventive effects of Cetrorelix on the changes induced by Cisplatin on spermatogenic and myoid cells and basal lamina of seminiferous ducts in the testis of Balb/C mouse
dariyoush mohammadneja jafar soleymanirad ameneh mohammadiroshandehCisplatin used in chemotherapy can have side effect on spermatogenesis. As it is known Gonadotropine hormones (LH, FSH) affect spermatogenesis. It seems by suppressing secretion of LH and FSH during chemotherapy, spermatogenesis could stopped which could result in prote MoreCisplatin used in chemotherapy can have side effect on spermatogenesis. As it is known Gonadotropine hormones (LH, FSH) affect spermatogenesis. It seems by suppressing secretion of LH and FSH during chemotherapy, spermatogenesis could stopped which could result in protection of the cells from cisplatin side effects. The aim of the present study is to investigate the preventive effect of cetrorelix (GnRH antagonist) on spermatogenic defect produced by Cisplatin. In the present study thirty adult male mice aging 6-8 weeks were divided into 3 groups as: Control, Experimental 1 and Experimental 2. Experimental 1 received Cisplatin for 5 days as 2.5 mg/kg intraperitoneally and Experimental 2 received 0.25 mg/kg cetrorelix (GnRH antagonist) one week before cisplatin treatment and continued for 3 weeks. After 35 days from last injection, testicular specimens were removed and prepared for light and electron microscopic study. The data were analyzed using ANOVA (Tukey) in all 3 groups. Histological results showed that nucleus of spermatogonia cells were more condensed and diameter of seminiferous tubules were reduced, in the group which received cisplatin in comparison with the control group. Histochemical studies showed an increase of apoptotic cells in the group which received cisplatin. Electron microscopy showed that in Experimental 1 group basment membrane was morphologically irregular and wavey and Myoid cells were thickened and contracted, but in Experimental 2 group the condition was similar to the control group. These results showed that injection of cetrorelix with cisplatin can protect spermatogenic cells against the side effects of cisplatin. Manuscript profile -
Open Access Article
417 - A brief overview on the application of cellulose as an efficient and effective catalyst in organic reactions
Abdulhamid Dehghani Milad Ghezelsofloo Yousef Delshad Soheil Dehghani SiyahakiThe production of renewable and valuable chemicals from renewable biomass sources such as cellulose has attracted global attention in order to create sustainable societies. Cellulose is the most abundant non-food biomass and is of great economic importance. Unlike tradi MoreThe production of renewable and valuable chemicals from renewable biomass sources such as cellulose has attracted global attention in order to create sustainable societies. Cellulose is the most abundant non-food biomass and is of great economic importance. Unlike traditional catalysts derived from petroleum sources, cellulose offers several advantages such as renewability, biodegradability and compatibility with the principles of green chemistry. The use of heterogeneous catalysis can allow researchers to develop environmentally safe processes. Cellulose-based catalysts have shown significant activity in a wide range of reactions including hydrogenation, oxidation and polymerization. Their versatility is due to their ability to support all kinds of metal nanoparticles that act as active catalysis sites. Stabilization of metal nanoparticles on cellulose brings several advantages, including improving stability, preventing the accumulation of nanoparticles, and increasing their dispersibility. Cellulose shows its potential to create a great revolution in green chemistry. Therefore, cellulose's versatility, sustainability, and tunable properties make it an essential catalyst for a greener future. The purpose of this review is to provide an overview of the use of cellulose as a catalyst in organic reactions by Iranian researchers. Manuscript profile -
Open Access Article
418 - Investigating Social Capital Level and its Regression Equation with the Organizational Excellence at the Islamic Azad University Organization
Maryam MousivandThe purpose of this study was to assess the level of social capital and its regression equation with the organizational excellence at the Azad University organization. This research was an applied research with a descriptive-correlational design in which 375 employees o MoreThe purpose of this study was to assess the level of social capital and its regression equation with the organizational excellence at the Azad University organization. This research was an applied research with a descriptive-correlational design in which 375 employees of the Islamic Azad University were randomly selected as the sample of the study. The social capital and organizational excellence questionnaires were used for collecting the data. Based on Cronbach''s alpha, the validity of the social capital (0.84) and organizational excellence (0.88) questionnaires were calculated. The data analysis was done using Pearson correlation, multiple linear regression, ANOVA and structural equations model in SPSS and Lisrel softwares. The results showed that cognitive, communicative and structural aspects have the most significant impact on social capital of the Islamic Azad University, respectively. The level of social capital and organizational excellence at Islamic Azad University was assessed as being "average" and "poor", respectively. The results also indicated a significant and positive relationship (0.79) between social capital and organizational excellence at Islamic Azad University (p=0.000). The cognitive, communicative and structural aspects of social capital had the highest regression effect on organizational excellence, respectively, and all were significant predictors of organizational excellence at the Islamic Azad University (p Manuscript profile -
Open Access Article
419 - Assessing the performance of education management in Miandoab township based on EFQM in 2011
Sadegh Maleki Avarsin Behnam Talebi Hossein BabazadehThe present study aimed at assessing the performance of education management in the city of Miandoab based on EFQM in 2011. The research method was descriptive survey. The sample size was selected through simple random sampling included 28 people. To test the hypotheses MoreThe present study aimed at assessing the performance of education management in the city of Miandoab based on EFQM in 2011. The research method was descriptive survey. The sample size was selected through simple random sampling included 28 people. To test the hypotheses the t-statistic was used. The main instrument utilized for data collection was a standard questionnaire which has been organized based on (EFQM) model. Each of the sub-criteria included objective examples and guided points, arranged based on the characteristics of education. The sub-criteria posed 264 questions based on RADAR logic. Having participated in a 2-day orientation course, the subjects were given the questions. The performance of the management was assessed through self assessment by the employees. To test the validity of the questions some experts were consulted, and to determine the reliability of the questions Cronbach's alpha was used which was α=0.95. The study consisted of 2 questions. Miandoab's Education Administration gained 506.59 out of 1000 for its performance based on the EFQM. The performance of the administration in empowerment criteria gained 49.83 percent and results criteria 51.48. Accoring to the findings of the study it was suggested to enhance the performance of the organization. The results showed that, the performance of the administration management in Miandoab city based on EFQM model in results criteria was better than empowerment criteria. Manuscript profile -
Open Access Article
420 - Designing and Validating an Excellence Organizational Climate Model in Private Banks in Iran
Alireza Moradisaleh Hassan Rangriz Akbar Hassanpoor Bijan AbdollahiThis mixed-methods research was conducted to identify and design the dimensions, components and factors of an excellence organizational climate and validate it. The qualitative phase of the study was based on the grounded theory and MAXQDA software while the quantitativ MoreThis mixed-methods research was conducted to identify and design the dimensions, components and factors of an excellence organizational climate and validate it. The qualitative phase of the study was based on the grounded theory and MAXQDA software while the quantitative stage was conducted using SPSS software. The research population comprised Iranian private banks from which a convenient sample was selected based on theoretical adequacy and availability during the qualitative phase. Interviews were run with the sample to reach the theoretical saturation. Further, the quantitative phase of the study started with a sample of 318 participants who had been selected based on a multi-stage cluster sampling procedure from 1815 employees using the Cochran formula. The reliability and validity of the qualitative and quantitative phases of the research were checked through Lincoln and Guba evaluation and Cronbach's alpha, respectively. The collected data were analyzed to explain the paradigmatic model of the excellent organizational climate that was then validated via Wilcoxon test. The findings indicated that the main dimensions of the excellence organizational climate include "employee credibility", "employee and management mutual respect" and "employees’ honoring the job and the organization" and that this model can promote organizational efficiency and profits, productivity, quality of professional life and organizational culture, branding and more willingness to work in a competitive environment. Manuscript profile -
Open Access Article
421 - Evaluating the Performance of Management in Engineer Traininig Centers of Iran Based on Fuzzy Approach: A case study
Hassan Khademi Zare Mahnaz zareiOne of the key factors that lead organizations and high education centers to deficieney is that their processes and obtained results are not evaluted well. In the case that high education centers realize their positions well and become aware of their weaknesses, they wi MoreOne of the key factors that lead organizations and high education centers to deficieney is that their processes and obtained results are not evaluted well. In the case that high education centers realize their positions well and become aware of their weaknesses, they will no doubt attempt to eliminate those deficiencies. The purpose of this research, whose implementation scope is one of the technical-engineering complexes, is to present a method for the evalution of the performance of management in engineer training centers based on the European Foundation for Quality Management (EFQM) excellence model. Since the existing decision – making environment of high education centers, like many other organizations, is generally fuzzy and vague, for a further adjustment of the mentioned method with the existing situations of high education centers the proposed model is designed in fuzzy environments so that we would be able to evaluate the management performance of high engineering education centers in a more accurate way. Manuscript profile -
Open Access Article
422 - Determination of Key Employee Dexterity Factors with a Focus on Promoting Social Welfare and Functioning: A Case Study of Iran Health and Cellulose Industry
Reza Aghaee Reza Aghaee Asghar AghaeeEmployee dexterity is a fundamental and functional issue in organizations and industries operating in the present century. Organizations operating actively and dynamically in modern business environments face social functions which have to be taken into account fo MoreEmployee dexterity is a fundamental and functional issue in organizations and industries operating in the present century. Organizations operating actively and dynamically in modern business environments face social functions which have to be taken into account for the organization to survive and to function adequately. Therefore, the present descriptive survey aimed to investigate key employee dexterity factors focused on promoting social welfare and functioning in Iran Health and Cellulose Industry in order to offer a theoretical and conceptual framework. To serve the purpose, the contemporary literature on employee dexterity was reviewed using the Fuzzy Delphi Method to identify key influential factors can promote social functioning and the Fuzzy DEMATEL technique was applied to offer a systematic model explaining the relationships among the identified factors The findings highlighted adaptation to change, flexibility, pace of assigning and carrying out assignments, utilizing appropriate technology, updated skills, capability, multifunctional skills and accountability as the most effective factors. Adaptation to change and the pace of carrying out assignment were identified as the most influential and the most influenced factors, respectively. Manuscript profile -
Open Access Article
423 - Social participation of celebrities in virtual space and factors affecting it among the youth of Mazandaran province
Mohammad Javad Esmaili Aboalghasem Heidarabadi Manouchehr Pahlavan -
Open Access Article
424 - The Effect of Six Weeks of Selected Aerobic Training on Some Physiological Factors in Elderly Men
Mohsen Khodakaramyan Mehran Ghahramani Nahid Mohammadi Javid Parisa BanaeiIntroduction: Aging is a stage of life that is associated with physiological changes. The aim of this study was to investigate the effect of six weeks of selected aerobic training on some physiological factors in elderly men.Materials and methods: In this quasi-experime MoreIntroduction: Aging is a stage of life that is associated with physiological changes. The aim of this study was to investigate the effect of six weeks of selected aerobic training on some physiological factors in elderly men.Materials and methods: In this quasi-experimental and applied study, 48 sedentary male elderly volunteers with the age range of 60 - 70 years were selected as the statistical sample in Gilan-e-Gharb and divided into two groups of aerobic training and control (n= 24, in each group). The training protocol was performed for six weeks, three sessions per week and each session lasted one hour with an intensity of 55% of the maximum heart rate. Aerobic capacity, heart rate, systolic blood pressure, red blood cells and hemoglobin were measured before the study and also 48 hours after the last training session. The Kolmogorov-Smirnov, independent samples t-test and dependent samples t-test were used to analyze the research findings (P≤0.05).Findings: Six weeks of aerobic training had a significant effect on improving aerobic power, heart rate, systolic blood pressure, red blood cells, and hemoglobin in elderly men (P = 0.001).Conclusion: It seems that six weeks of aerobic training can be used to improve cardiovascular risk factors as well as hematological factors in elderly men. Manuscript profile -
Open Access Article
425 - Urban expansion and physical development simulation using fuzzy cellular automata (FCA).Case Study: Ahwaz City
Saaid zangane shahrAki Morteza omidi Pour yousef tazesh ateena moenmehrThis study is proposed a model of urban expansion based on cellular automata principles and fuzzy logic approach. The most effective indicators were first selected using the DEMATEL method. The weight of each indicator was then obtained with the help of the prepared str MoreThis study is proposed a model of urban expansion based on cellular automata principles and fuzzy logic approach. The most effective indicators were first selected using the DEMATEL method. The weight of each indicator was then obtained with the help of the prepared structure using the Analytic Network Process (ANP). Three satellite images of 2003, 2007, and 2013 were used to simulate urban growth of Ahvaz in the year 2020. The selected base year was 2003. After performing preprocessing operations, the images were classified using the maximum likelihood method. The combination of fuzzy logic and the classic cellular automata model was made operational by defining the transition rules using the degrees of fuzzy membership. The Kappa index was employed in two stages to study accuracy of the images. The images of the base year were first classified and their accuracy was examined, and the accuracy of the simulated images with respect to reality was also investigated for the year 2007 and then simulation of the images of the other years was performed. Since the degree of accuracy of the model was considered acceptable, the linear regression model and the matrix of transition probabilities were employed for simulation in 2020. Results indicated the model enjoyed acceptable accuracy. It also yielded more realistic results in urban simulations compared to the classic CA method. Moreover, and growth and development of Ahvaz in different periods did not take place in any specific direction but rather was completely irregular and occurred in all directions. Manuscript profile -
Open Access Article
426 - Prediction of the Peak Ground Acceleration for Zagros Earthquakes Using ANFIS and Data Partitioning Approach
seyyed Mohamadreza tabatabaei Roohollah kimiaefar Alireza Hajian Alireza AkbariIn this research, the prediction of Peak Ground Acceleration (PGA) is investigated through training the Adaptive Neuro Fuzzy Inference System (ANFIS) network using data partitioned into inlier and outlier groups. The partitioning procedure is based on an automated metho MoreIn this research, the prediction of Peak Ground Acceleration (PGA) is investigated through training the Adaptive Neuro Fuzzy Inference System (ANFIS) network using data partitioned into inlier and outlier groups. The partitioning procedure is based on an automated method which uses K Nearest Neighbor (KNN) search and Local Linear Model Tree (LOLIMOT) methods. The mentioned proved to enhance the prediction procedure at least 36 percent with respect to normal training mode with no data partitioning. Hereafter, a PGA catalogue reported by the Iranian ground acceleration network with 1571 records was used and the trained network was used for predicting the PGA map around the Mormori, 2014 earthquake epicenter. We used spatial information of the epicenter and the site, earthquake magnitude, Vs30, depth of the hypocenters and the epicentral distance foe the sites. The resulted map adapts well to the official report of the mentioned earthquake for the PGA analysis published by the International Institute of Earthquake Engineering and Seismology (IIEES). Finally, it is concluded that using machine learning algorithms could be beneficial in the cases where adequate data-sets are not provided by the seismological networks specifically in the concept of the strong ground motion analysis. Manuscript profile -
Open Access Article
427 - Land Use Changes Modeling and Future Predictions Using CA-ANN Simulation in the Watershed of 25 (Shenroud, Siahkal)
Roghayeh JahdiIn this study, we analyzed the spatial–temporal trends of land use dynamics from 2000 to 2021 using remote sensing data. The image classification was based on three main land use classes, i.e. forest, artificial areas (agriculture and built-up), and other natural MoreIn this study, we analyzed the spatial–temporal trends of land use dynamics from 2000 to 2021 using remote sensing data. The image classification was based on three main land use classes, i.e. forest, artificial areas (agriculture and built-up), and other natural areas (bare lands, grassland, plantation, shrubland, water bodies, and woodlands). Maps of land use changes in the area for 2000-2021 show that built-up areas have increased by 9.3%. In contrast, forest and other natural areas decreased by 7.1% and 2.2%, respectively. In addition, an integrated CA-ANN (Artificial Neural Networks- Cellular Automata) model was used to predict land use changes from 2021–2042. The percentage of correctness for the simulation was 91%, and the overall kappa value was 0.86. Similar to the classified maps in 2000-2021, the prediction maps from 2021–2042 illustrated increasing trends in built-up areas by 4.7% and decreasing trends in the forest by 4.26% and other natural areas by 0.4%. In this work, we implemented ordinary least squares (OLS) regression models to predict land cover changes in the study area as a function of explanatory variables [elevation, slope, and proximity variables - distance to the city center, roads, villages, and streams-]. The results of the OLS models showed a relatively good performance for predicting land use changes with an R-squared value greater than 0.5. These results provide important knowledge that can help develop future sustainable management and planning and help managers make informed decisions to improve environmental and ecological conditions. Manuscript profile -
Open Access Article
428 - Forecasting Changes in the Morphology of Sefid Rood River Using Arc GIS
Aghil Madadi Tayebeh Babaei olam Alireza GhodratiConsidering the flood events, especially for the settlements around the rivers, the lack of correct information about the consecutive changes of the river bed and its movement in the coming years is one of the important scientific issues of watershed management, therefo MoreConsidering the flood events, especially for the settlements around the rivers, the lack of correct information about the consecutive changes of the river bed and its movement in the coming years is one of the important scientific issues of watershed management, therefore, due to insufficient information about the behavior of the rivers, the settlements along the rivers in the coastal areas are constantly damaged. The scope of this research is from the border of Konik Kohestan to Jalga. The purpose of this research is to predict the changes in river morphology (channel width and measurement of Pichanroudi and river curvature coefficient) in the coastal areas of the north of the country through the integrated methods of remote sensing with the model of Markov automatic weighing cells. Sefidroud, as the largest and most important river on the southern shores of the Caspian Sea, plays an important role in the life, activities and human capital of the region. The morphological factors of the river and its surroundings and the prediction of future conditions can be effective and necessary in the planning and preparation of coastal plains. In this research, the Landsat 5, 7 and 8 satellite images of 2002, 1987 and 2018, along with the data of changes in the level of the Caspian Sea and Sefidroud Dubai, field surveys and Envi 5.3, ArcGIS 10.4.1 and Idrisi TerrSet software as The research tool was used. First, the probability values of land use conversion in 2018 were obtained based on the integrated model of the Markov chain and automatic cells. The results showed that the integrated model has high precision and accuracy to predict the future pattern. Then, according to the accuracy and accuracy of the model output, the prediction map of land use and river morphology for 2030 was prepared. By fitting the two maps of 2018 and the forecast of 2030, possible changes in the river environment were obtained and analyzed in four areas. Finally, using the data of changes in the level of the Caspian Sea and the annual discharge of the Sefidroud River, the trend of changes and prediction of the model was investigated. The most likely changes are due to man-made facilities. Erosion processes, change of Pichanroodi and flooding in the distance from Sangar Dam to Luman village as lateral displacement of the channel and intensification of Pichanroodi, Kisem village and the city of Astana Ashrafieh and Azadsara to Lichah as flooding of human facilities and in the area of Kiashahr, Bojag wetland and delta Sefidroud is changing the position of the estuary and moving to the west of the river channel, according to the results of the survey of the cross section of the river channel in the three periods of 1987, 2002 and 2018, there has been a decrease in the width of the channel. Manuscript profile -
Open Access Article
429 - Extraction of Hemicellulose and Lignin from Sugarcane Bagasse for Biopolymer Films: Green Process
Sifiso Nkosi Krishnan Kanny -
Open Access Article
430 - Band-Gap Tuning Of Electron Beam Evaporated Cds Thin Films
Mohamad Javad Eshraghi Nima Naderi -
Open Access Article
431 - Effect of Quartz Particle Size on Sintering Behavior and Flexural Strength of Porcelain Tiles Made from Raw Materials in Uganda
Ochen William Florence D&#039;ujanga Bosco Oruru -
Open Access Article
432 - Fabrication of the Ordered Nanocells of Anodic Aluminum Oxide and the Generation of Zn-Mn Ferrite Phase within Them
masoud soltani Zeinab Erfani Gahrouei Saeed Akhavan Ali Shafyei -
Open Access Article
433 - The Effect of Morphology of SOFC Layers Made by 3D Printer on the Electrochemical Properties of the Cell
Keyvan Mirzaee Fashalameh Zahra Sadeghian Ramin Ebrahimi -
Open Access Article
434 - Development and Evaluation of Nanomagnetic Carrier for the Controlled Loading and Release of Celecoxib
Shabnam Ahmadvand Maryam Kargar Razi Babak Sadeghi Seyedeh Sara Mirfazli -
Open Access Article
435 - Cerium Oxide Nanoparticles as an Accelerating Agent for Zinc Phosphate Coatings with Enhanced Corrosion Resistance
Mohammad-mehdi Akbari Behrooz Shayegh Boroujeny Mehdi Raeissi -
Open Access Article
436 - Evolution of Biological Properties of Bioactive Diopside and Wollastonite for Bone Tissue Engineering
Ruhollah Zamani Foroushani Ebrahim karamian Mohammad Rafienia -
Open Access Article
437 - Predicting the growth and development of Bandar-e-Gaz Town Using Fuzzy Cellular Automata (FCA)
دنیائی Donyaiiautomated cell-based models (CAs) are defined based on two-value logic and in a non-flexible manner. Combining fuzzy logic with the classical cellular automata model makes it possible to model the uncertainty governing the urban development simulation process by definin Moreautomated cell-based models (CAs) are defined based on two-value logic and in a non-flexible manner. Combining fuzzy logic with the classical cellular automata model makes it possible to model the uncertainty governing the urban development simulation process by defining the transition rules using the degrees of fuzzy membership. This study presented the model of urban expansion based on the fuzzy cellular automata. The most effective indicators were first selected using the DEMATEL method. The weight of each indicator was then obtained using the Analytic Network Process (ANP). Three satellite images from 2012, 2014 and 2019 were used to simulate urban development in the study area (Bandar-e-Gaz Town) for the year 2100.After preprocessing; the images were classified for all three periods by the maximum likelihood method. The Kappa index was used to check the accuracy of the maps in two steps. The images of the base year were first classified and their accuracy was examined, and then the simulation of the images of the other years was performed and their accuracy again was examined. Since the degree of accuracy of the model was considered acceptable, the linear regression model and matrix of transition probabilities were used for simulation. The results of this study showed that the proposed model is acceptable so that it works better in urban simulation than the classical model of CA. Also, the growth and development of Bandar-e-Gaz town in different periods has been more in the eastern and western parts. Manuscript profile -
Open Access Article
438 - Phytoremediation of Cadmium by using the Cupressus arizonica and Fraxinus excelsior species (case study: Isfahan)
saeed kardar seyed reza Fatemi-talab keyvaan Saeeb amin khademiAbstract Industrial activities cause the arrival of large amounts of heavy metals into the atmosphere and the usages of plant species can be effective in reducing the pollution of heavy metals. This research attempted to evaluate the amount of Cadmium absorption in dif MoreAbstract Industrial activities cause the arrival of large amounts of heavy metals into the atmosphere and the usages of plant species can be effective in reducing the pollution of heavy metals. This research attempted to evaluate the amount of Cadmium absorption in different parts of Cupressus arizonicaand Fraxinus excelsiorin Isfahan. For this reason samples from leaves and surface roots were collected in polluted sites and controlled site at the end of spring and summer and the concentration of Cadmium was measured by Atomic Absorption (AA). The results indicated that the amount of Cadmium absorption in the above ground organs of Cupressus arizonicawas more than the Fraxinus excelsiorspecies. In both species, the trees leaf absorbs Cadmium more than the root. The Azadi Street absorbs Cadmium more than other site. The most and the least amount of cadmium absorption was observed on September and July respectively. Manuscript profile -
Open Access Article
439 - Investigating the Effect of Plant Growth Regulators (GA3 and 2, 4-D) on the Reduction of the Physiological Disease of Thomson-Novel Orange Fruit
shahruz habibi ali ebadi alireza ladan moghadam siavash raytpanahCitrus is a major product of the gardens of the north of the country, and since oranges have better storage, they also have a larger share of the gardens. Oranges have a very good market and have a good market and have the highest production, but because it has thin nav MoreCitrus is a major product of the gardens of the north of the country, and since oranges have better storage, they also have a larger share of the gardens. Oranges have a very good market and have a good market and have the highest production, but because it has thin navel and skin, it is sensitive to tension and has a physiological disorder Fruiting. In order to reduce this complication, a randomized complete block design with 2 and 4 dichlorophenoxy acetic acid (2, 4-D) at concentrations of 0-10 and 20 mg / L and gibberellic acid GA3 (with concentrations of 0- 50 and 100 mg / L at flowering time, petals fell immediately after the physiological fall of fruit for two consecutive years (2016-2017). In this experiment, the percentage of fruit grazing, fruit yield, fruit skin thickness, soluble solids, cellulase and superoxide dismutase enzyme activity were measured. Based on the results obtained from the comparison of the meanings, the maximum thickness of the fruit skin, soluble solids, performance and activity level of the enzyme superoxide dismutase, as well as the lowest activity of the enzyme cellulase Manuscript profile -
Open Access Article
440 - Effect of the growth retardant chlormequat chloride (CCC) and different levels of nitrogen on some physiological and biochemical characteristics and yield of barley (Hordeum vulgare L.) cultivar makuyi
Ahmad Afkari Mitra AbbasiTo study the effects of different concentrations of chlormequat chloride and different levels of nitrogen on some physiological and biochemical characteristics and yield of barley (Hordeum vulgare L.) cultivar makuyi a factorial randomized complete block design was used MoreTo study the effects of different concentrations of chlormequat chloride and different levels of nitrogen on some physiological and biochemical characteristics and yield of barley (Hordeum vulgare L.) cultivar makuyi a factorial randomized complete block design was used with 4 replications in spring 2015. Treatments included chlormequat chloride concentrations (0, 500, 1,000, and 1500 mg/ha) and nitrogen at 3 levels (50, 100, and 150 kg/ha). Results suggest a significant difference between interaction effects of chlormequat chloride and nitrogen fertilizer on chlorophyll content, relative water content, yield and protein percentage, and activity of superoxide dismutase and catalase enzymes at 1% probability level and in the number of seeds per spike, 1000 seed weight, and glutathione peroxidase enzyme activity at 5% probability level. An increase in the consumption of nitrogen fertilizer decreased the relative water content of leaves due to reduced leaf water potential. Chlormequat chloride by transferring sufficient photosynthetic material to the seeds played an important role in their filling and increased seed weight. Also, the activities of superoxide dismutase, catalase, and glutathione peroxidase enzymes were decreased by increasing the consumption of chlormequat chloride concentration and nitrogen uptake. In general, through applying 1500 mg/ha chlormequat chloride and 150 kg/ha nitrogen, the highest chlorophyll content, relative water content, yield components, yield, and protein percent were obtained. Manuscript profile -
Open Access Article
441 - The effect of interval irrigation and growth regulators on some morphophysiological traits of cotton (Gossypium hirsutum L) cultivars
eshaq arekhi Hossein Ajam Noruzi Kamal Ghasemi Bezdi elham faghaniTo study the effect of interval irrigation and growth regulators on morphophysiological traits of cotton cultivars, an experiment was conducted as a split factorial in randomized complete block design in 2017 and 2018 in Hashemabad Cotton Research Station in Gorgan, Ira MoreTo study the effect of interval irrigation and growth regulators on morphophysiological traits of cotton cultivars, an experiment was conducted as a split factorial in randomized complete block design in 2017 and 2018 in Hashemabad Cotton Research Station in Gorgan, Iran. Treatments consisted of intervals of irrigation at two levels (two weeks and four weeks) as the main factor and six-level growth regulator treatments (control, benzyl adenine, abscisic acid, salicylic acid, brassinosteroid, and cycocel) and three cotton cultivars (Golestan, Kashmar, and Shayan) were also considered as sub-factors. The results of this study showed that proline content and relative water content of leaf decreased with water deficit stress. Maximum proline content (3.55 µg/g fresh weight) was obtained from Shayan cultivar with salicylic acid. Benzyl adenine and brassinosteroids increased relative leaf water content. The highest cell membrane stability (2.998%) was observed in Kashmar cotton cultivar and two-week interval irrigation, and Cycocel increased the membrane stability by 15%. Plant height, number of flowers, and number of bolls were affected by growth regulators, irrigation intervals, and cultivars. With increasing irrigation period, plant height, flower number, and boll number decreased in all cultivars, but under drought stress, Golestan cultivar had more flowers and boll number than other cultivars. Cycocel, salicylic acid, and brassinosteroids significantly increased flowering of cultivars at both years and both irrigation intervals. Benzyl adenine and brassinosteroids increased plant height more than 7% and abscisic acid, cycocel, and salicylic acid decreased plant height compared with control. Application of abscisic acid reduced the number of bolls by 22% compared with the control. Overall, growth regulators, especially cycocel and salicylic acid, increased the morphophysiological traits of cotton cultivars indicating their positive effect on drought tolerance and it could play a role in moderating stress effects under stress conditions. Manuscript profile -
Open Access Article
442 - Effect of foliar application of salicylic acid and biofertilizerson on yield and some biochemical traits of basil (Ocimum basilicum L.) under water stress
Ahmad AfkariIn order to study of the effect of foliar application of salicylic acid and biofertilizerson on yield and some biochemical traits of basil (Ocimum basilicum L.) under water stress, was investigated using a factorial experiment based on a randomized complete block design MoreIn order to study of the effect of foliar application of salicylic acid and biofertilizerson on yield and some biochemical traits of basil (Ocimum basilicum L.) under water stress, was investigated using a factorial experiment based on a randomized complete block design in triplicate within the 2019 crop year in the protected area of Horand city of the province of East Azarbaijan. Experimental treatments included the first factor of drought stress at three levels (70, 140 and 210 mm of evaporation from Class A evaporation pan), the second factor of seed inoculation with bacteria at five levels (no inoculation as control, inoculation with Azotobacter, Pseudomonas, Azospirillum and co-inoculation with Azotobacter, Pseudomonas and Azospirillum), and the third factor of salicylic acid foliar application at four levels (0, 0.5, 1 and 1.5 mM). With the application of dehydration, cell membrane stability, maximal photochemical efficiency of photosystem II and grain yield in basil decreased and carbohydrate accumulation, antioxidant enzyme activity, malondialdehyde content and essential oil content increased. The results of comparing the mean interaction of drought stress and biofertilizers showed that the highest grain yield (917.11 kg / ha) and maximum photochemical efficiency of photosystem II (0.713) were obtained from 70 mm evaporation treatment and the co-inoculation of bacteria (Azotobacter, Pseudomonas and Azospirillum). Salicylic acid (SA) foliar application increased 41.33%, 54.17%, 24.43% and 38.98% of glutathione peroxidase activity, leaf soluble carbohydrates, membrane stability index and essential oil content, and decreased the content of MDA by 54.72% respectively. According to the obtained results, foliar application with salicylic acid and the combined use of bacteria (Azotobacter, Pseudomonas and Azospirillum) could partially eliminate the negative effects of drought stress and improve the yield and quality of basil. Manuscript profile -
Open Access Article
443 - Compensate for reduced yield due to late water stress by using growth enhancers in the tillering stage of wheat (Triticum aestivum L.)
Mehrnoush Eskandari Torbaghan sayd fazel fazeli kakhki Mohammad JoleiniThe application of foliar spraying can be practical in critical stages for alleviating plant nutritional needs in the short term. To investigate the effect of growth enhancers in the tillering stage of wheat on the compensation of required compounds from storage sources MoreThe application of foliar spraying can be practical in critical stages for alleviating plant nutritional needs in the short term. To investigate the effect of growth enhancers in the tillering stage of wheat on the compensation of required compounds from storage sources to grain in the remobilization process in the stopping last irrigation, an experiment was carried out in a split-plot arrangement based on a randomized complete block design with three replications at the farm of Kashmar research station in 2020-2021. The main plots were two variety of wheat: V1: Sirvan and V2: Rakhshan, the subplots were growth enhancers including (T1: Control, T2: Urea phosphate (10 kg.ha-1) + solopotas (8 kg.ha-1) + amino acid (2:1000); T3: Urea phosphate (10 kg.ha-1) + solopotas (8 kg.ha-1) + micronutrient (2:1000); T4: Urea phosphate (10 kg.ha-1) + solopotas (8 kg.ha-1) + humic acid (2:1000). The results showed that the highest plant height was obtained from T3 treatment in the Sirvan cultivar. In both Sirvan and Rakhshan varieties, the highest peduncle length was recorded from a foliar spray of T3. The highest plant dry weight (1290 g.m-2) per square meter was also obtained from T2 in Sirvan. Grain weight per square meter in the Sirvan cultivar was 651, 582, and 462 g.m-2 from the application of T2, T3, and T4, respectively, which was higher than the Rakhshan cultivar in these treatments. The highest amount of photosynthesis was 19.1 μCO2mol.m-2. s-1, stomatal conductance, and intercellular CO2 (Ci) were obtained in the Sirvan cultivar by T2 application. In general, the effect of T2 treatment on photosynthesis and yield indicates compensation for the lack of grain yield (52% increase) and biomass (51%) due to the last water stop in the Sirvan cultivar. Manuscript profile -
Open Access Article
444 - The effect of humic acidic and cycocel on yield, yield components, and photosynthetic material remobilization of wheat (Triticum aestivum L.) under end-of-the-season drought stress conditions
Maryam Shirvanian Mani Mojaddam Shahram Lack Mojtaba Alavifazel Seyed Keyvan MarashiIn order to investigate the effect of humic acidic and cycocel on yield, yield components, and remobilization of wheat photosynthetic materials under end-of-the-season drought stress conditions, a split factorial experiment was conducted based on a randomized complete b MoreIn order to investigate the effect of humic acidic and cycocel on yield, yield components, and remobilization of wheat photosynthetic materials under end-of-the-season drought stress conditions, a split factorial experiment was conducted based on a randomized complete block design with three replications in field in Ahvaz during two years (2017-19). The main factor of drought stress at the end of the season with two levels of normal irrigation and cessation of irrigation in the post-pollination stage, cycocel with three levels of water as a control, 1.5 g/l, and 3 g/l, and humic acid with three levels of non-foliar application (water as control), 2 liters per hectare, and 4 liters per hectare were factorial sub-factors. Results showed that the interaction of end-of-the-season drought stress and cycocel on grain yield and number of grains per spike was significant. The highest grain yield (4840.5 kg ha-1) was obtained by applying 3 g/l cycocel under normal irrigation conditions, which did not show a statistically significant difference from the application of 3 g/l cycocel under drought stress at the end of the season. Application of humic acid had a positive and significant effect on all test traits. The highest grain yield, number of grains per spike, and 1000-grain weight were obtained from the application of 3 liters per hectare of humic acid under normal irrigation conditions. Under end-of-the season drought stress, the current photosynthesis and the share of current photosynthesis decreased by 29% and 10%, respectively while remobilization and contribution of remobilization increased by 16% and 34%, respectively. In general, to increase the rate of grain yield under optimal conditions and reduce the drop in stress conditions, growth regulators such as cycocel by a concentration of 3 g/l and organic acid fertilizer by the concentration of 4 liters per hectare are recommended. Manuscript profile -
Open Access Article
445 - Phytochemical assessment and comparison of Thymus daenensis Celak. essential oil in natural habitats and field conditions
jalal khorshidi Majid Shokrpour Vahideh NazeriIn the domestication process of medicinal plants, evaluation of qualitative and quantitative changes of active ingredients is necessary after transfer from natural habitat to field conditions. Thymus daenensis Celak is an endemic vulnerable medicinal plants of Iran, whi MoreIn the domestication process of medicinal plants, evaluation of qualitative and quantitative changes of active ingredients is necessary after transfer from natural habitat to field conditions. Thymus daenensis Celak is an endemic vulnerable medicinal plants of Iran, which become especially important due to high essential oil content. In this study, essential oil quantity and quality of three ecotypes from Hamedan, Markazi and Lorestan provinces were evaluated under natural habitat and field conditions. Aerial parts of plants in natural habitat and field were harvested in full bloom stage and their essential oils were obtained by water distillation method using Clevenger apparatus and analyzed by GC and GC/MS. Results indicated that essential oil content of the ecotypes was significantly different in natural habitat, but this difference was not significant in field. Essential oil of Hamedan province ecotype in field was more than natural habitat, but in two others ecotypes, essential oil content in natural habitat was greater than field conditions. Essential oil components in all ecotypes were almost same in both natural habitat and field, but there were differences in dominant components and their amount in natural habitat and field conditions. Finally, the highest content of essential oil (5 %) and thymol (75.45 %) were observed in Markazi and Lorestan ecotypes under natural habitat, respectively. As the results indicated, essential oil content and thymol of Thymus daenensis Celak was strongly influenced by habitat conditions and therefore study and determine the most appropriate secondary culture medium is necessary for domestication of this plant Manuscript profile -
Open Access Article
446 - Evaluation the effect of elicitors on antioxidant properties and mycelial secondary metabolites of Stereum hirsutum, Hyphodontia paradoxa and Arthrinium arundinis from Golestan province
lazemi golaem vahide payamnoor jamile nazari omran alishahThe aim of this study was to evaluate the effect of elicitors on antioxidant properties and mycelial secondary metabolites of Arthrinium arundinis, Lichen symbiont, and Hyphodontia paradoxa and Stereum hirsutum hosted by Betula pendula . In the summer of 2016 preliminar MoreThe aim of this study was to evaluate the effect of elicitors on antioxidant properties and mycelial secondary metabolites of Arthrinium arundinis, Lichen symbiont, and Hyphodontia paradoxa and Stereum hirsutum hosted by Betula pendula . In the summer of 2016 preliminary sampling was performed from tree barks of Siah-Marzkouh, Golestan province, from an altitude of 2400 m above sea level. Then, fungal purification was achieved. In 2018, biennial mycelial reserves were used to investigate changes in secondary compounds. The following treatments were applied as elicitor: sodium nitrate, nanofibers cellulose and magnesium sulphate. Initial evaluation of triterpenoids was performed by HPLC using standard betulin and betulinic acid, and LC-MS was used to confirm the corresponding peak as triterpenoid. Antioxidant properties in mycelia of these fungi were studied by DPPH method. Based on the results, the highest peak of triterpenoids which are derivatives of betulin was in H. paradoxa treated by nanofibers cellulose, while in S. hirsutum it was by sodium nitrate (6.5 and 6.37 times in comparison to control, respectively). In A. arundinis, elicitors had no effect on triterpenoids amount and significantly reduced it. The antioxidant activity of H. paradoxa in the control treatment was 83.1% and the induction of elicitors had the opposite effect on this activity. The antioxidant activity of A. arundinis decreased from 82.05 to 87.12% with magnesium sulfate elicitor, meanwhile by adding sodium nitrate to the medium it increased from 24.62 to 86.04%. Manuscript profile -
Open Access Article
447 - Phytochemical Study of Ethanolic Extract of Fraxinus excelsior L. in Different Habitats of Hyrcanian Forests in Mazandaran Province
Masoomeh Soleimany Rahim abadi seyed mohammad hosseini nar hamid jalilvand seyed mohammad hojatti poriya biparvaFraxinus excelsior L. is a forest species with versatile biological and medicinal activities that its extracts are used as a model for making new compounds in the treatment of various human diseases. In this study, in order to investigate how the biochemical characteris MoreFraxinus excelsior L. is a forest species with versatile biological and medicinal activities that its extracts are used as a model for making new compounds in the treatment of various human diseases. In this study, in order to investigate how the biochemical characteristics of this forest species are affected by environmental conditions, four habitats of Perchink, Amreh, Alandan and Qarnsara with an altitude of 200 to 1400 meters, were selected in Tajan and Siahroud watersheds located in Mazandaran province. In each habitat, skin samples were taken from 3 trees (repeated) in summer. Ethanol extracts were obtained by maceration and were analyzed by GC/MS and the physical and chemical properties of the soil samples were measured. The most important compounds of extracts were included: benzeneethanol (30.33-51.35%), d-allose (6.20-31.72%), scopoletin (14.65-26.83%), tyrosol acetate (5.37-9.06%), carvacrol (0-4.93%), homovanillyl alcohol (3.84- 6.53%) which increased with increasing altitude. Also, there was negative relationship between the identified compounds and soil nutrients. Among them, only polyphenol tyrosol acetate behaved differently from the other compounds in a way that showed a negative relationship with the altitude factor and a positive correlation with the amount of carbon and absorbable phosphorus in the soil. Also, the chemical composition of d-allose was not observed in Perchink habitat. These results were showed that the chemical properties of this tree skin are affected by habitat conditions, which caused increases the species' resistance to pathogens. As a result, considering that the amount of active ingredients in this species was higher at higher altitudes and the presence of these compounds increases the resistance to pathogens, it seems planting this species is more productive at higher altitudes to achieve multiple goals in afforestation. Manuscript profile -
Open Access Article
448 - بررسی فیتوشیمیایی اسانس گیاه دارویی Phlomis cancellata Bunge. در شمال ایران
مهنا دیلم صالحی محمد مهدوی جلال محمودی محمد اکبرزاده سیدفاضل میراحمدی -
Open Access Article
449 - Preparation of cellulose nanoparticle from cinnamon
golsum afshari Hakimeh Ziyadi -
Open Access Article
450 - The Morphology of Zinc Sulfide Nanocrystals Synthesized by Different Methods
Mina Adibi Sohrab Taghipoor Rava Parhizkar Seyed Mojtaba Mostafavi -
Open Access Article
451 - Synthesis of TiO2 nanorods with a microwave assisted solvothermal method and their application as dye-sensitized solar cells
Hossein Rezvani Nikabadi Saeed Khosroababdi -
Open Access Article
452 - Synergistic effects of Titanium dioxide nanoparticles and Paclitaxel combination on the DNA structure and their antiproliferative role on MDA-MB-231cells
Azadeh Hekmat Masoumeh Afrough Saeed Hesami Tackallou Faizan Ahmad -
Open Access Article
453 - Albumin binding and cytotoxicity assay of nickel oxide nanoparticles against primary hippocampal neural cells
Mojtaba Falahati Pegah Ghoraeian Ghoraeian Sara Haji Hosseinali -
Open Access Article
454 - The Investigation of the Toxicity of Palladium Nanoparticles on Human Lymphocyte
maryam zivari fard majid sharifi arian shojaei Seyed Mahdi Rezayat seyyedeh elaheh mousavi Mojtaba Falahati -
Open Access Article
455 - Green Synthesis and Characterization of Bimetallic (Ag-Cu) Nanoparticles from Leaf extract of Celtis integrifolia (Hackberry) and it’s Antimicrobial Activity
Nasiru Yahaya Wilson Lamayi Sulaiman MuhahammadThe (Ag-Cu) bimetallic nanoparticles was synthesized from the leaf extract of Celtis integrifolia using the silver nitrate (AgNO3) copper chloride (CuCl2) as a metal precursors. The synthesized bimetallic nanoparticles was characterized using UV-visible spectrophotometr MoreThe (Ag-Cu) bimetallic nanoparticles was synthesized from the leaf extract of Celtis integrifolia using the silver nitrate (AgNO3) copper chloride (CuCl2) as a metal precursors. The synthesized bimetallic nanoparticles was characterized using UV-visible spectrophotometry, the celtis extract shows highest peak at 300nm due to plasma vibration and excitation of bio reduction capping agent Ag-CuNPs shows peak at 300nm which is due to surface Plasmon vibration, indicating the formation of bimetallic nanoparticles due to the excitation of the surface Plasmon vibration and phytochemical constituent present in the extract. FT-IR identify the functional groups present, SEM shows the morphology of the bimetallic Ag-CuNPs is partially merely crystalline and spherical in nature. XRD analysis of Ag-CuNPs showed face centered cubic structure (FCC) with average particle size of 54.42. The (Ag-CuNPs) bimetallic nanoparticles shows significant antibacterial and anti-fungal activity when tested against Escherichia-coli, pseudomonas aureginosa (Gram-negative), staphylococcus aures, Klebsella Pneumonia (Gram-positive) bacteria’s and two fungi Aspagillus niger and Candida using Augomentine and Fulcin as control drugs. Manuscript profile -
Open Access Article
456 - The effect of acid/cellulose ratio on the quality of Cellulose Nanocrystal (CNC) suspension
Nasrin Shahmiri Nahid Hassanzadeh Nemati Ahmad Ramazani Saadatabadi Massoud SeifiCellulose nanocrystals are promising materials for application in biomedicine, pharmaceutical and food industry. There are various methods for CNC synthesis, but acid hydrolysis is the most common one. The optimization of acid hydrolysis process is still in progress. In MoreCellulose nanocrystals are promising materials for application in biomedicine, pharmaceutical and food industry. There are various methods for CNC synthesis, but acid hydrolysis is the most common one. The optimization of acid hydrolysis process is still in progress. In the present study, different CNC suspensions were prepared to find out the more efficient acid ratio for CNC production. Whatman #1 filter paper was hydrolyzed via 64 wt% sulfuric acid at acid-to-paper ratio of 10:1 mL/g, 20:1 mL/g, 30:1 mL/g, and 40:1 mL/g. The synthesized CNCs were characterized by DLS, ELS and AFM. The suspensions with acid/cellulose ratio of 20:1 mL/g & 30:1 mL/g resulted in CNCs with more negative surface charge and uniform size. They also represented chiral nematic phase and regular self-organization after layer by layer deposition. It was found that the higher acid-to-paper ratio does not necessarily produce the high quality CNCs. Since the suspension that was prepared at acid/cellulose ratio of 40:1 mL/g had lower negative charge. The size and surface charge of CNCs are highly dependent to acid hydrolysis parameters and ultimately affect their behavior in nano-composites. In spite of many published papers around CNC synthesis by acid hydrolysis, there are still some details that must be addressed and investigated more to prepare the most efficient and applicable CNCs. Manuscript profile -
Open Access Article
457 - Albumin binding and cytotoxicity assay of nickel oxide nanoparticles against primary hippocampal neural cells
Sara Haji Hosseinali Mojtaba Falahati Pegah Ghoraeian -
Open Access Article
458 - Preparation of Symmetrical Tetraphenyl Porphyrin Metal Complexes and Their Spectroscopic Studies
S. Khaliq M. Danish M. Yasin R. Asim -
Open Access Article
459 - Synthesis of TiO2 nanorods with a microwave assisted solvothermal method and their application as dye-sensitized solar cells
Hossein Rezvani Nikabadi Saeed Khosroababdi -
Open Access Article
460 - Synthesis and characterization of Ag-doped TiO2 nanostructure and investigation of its application as dye-sensitized solar cell
Bibi Rahnejat -
Open Access Article
461 - 3D Graphene Biocatalysts for Development of Enzymatic Biofuel Cells: A Short Review
Seyed Mojtaba Mostafavi -
Open Access Article
462 - Preparation of cellulose nanoparticle from cinnamon
Golsoum Afshari Hakimeh Ziyadi -
Open Access Article
463 - Comparative Study of Nanostructured Zr-Fe2O3 and CNT Modified Zr-Fe2O3 Thin Films for Photo Electrochemical Generation of Hydrogen
Vibhuti Yadav Sadhana Tyagi Devbrat Pundhir Saral Kumar Gupta -
Open Access Article
464 - The Investigation of the Toxicity of Palladium Nanoparticles on Human Lymphocyte
Maryam Zivari fard Majid Sharifi Arian Shojaei Seyed Mahdi Rezayat Seyyedeh Elaheh Mousavi Mojtaba Falahati -
Open Access Article
465 - Synergistic effects of Titanium dioxide nanoparticles and Paclitaxel combination on the DNA structure and their antiproliferative role on MDA-MB-231cells
Azadeh Hekmat Masoumeh Afrough Saeed Hesami Tackallou Faizan Ahmad -
Open Access Article
466 - The Morphology of Zinc Sulfide Nanocrystals Synthesized by Different Methods
Mina Adibi Sohrab Taghipoor Rava Parhizkar Seyed Mojtaba Mostafavi -
Open Access Article
467 - Metadiscourse Markers in the Abstract Section of Applied Linguistics Research Articles: Celebrity vs. Non-celebrity Authors
DOR: 20.1001.1.23223898.2021.9.37.10.8
Parisa Ahmadi Javad Gholami Reza Abdi Zila Mohammadnia -
Open Access Article
468 - A Fuel-Cell Based Boost Converter Model Using Euler-Lagrange Equation
Atila Skandarnezhad -
Open Access Article
469 - Improvement of Fuel Cells Dynamic Response in Micro-Grids Using Ultra Capacitors
Pouria Maghouli Hossein Refahi -
Open Access Article
470 - Optimization of Stand-alone Hybrid PV/Wind/Fuel-Cell System Considering Reliability Indices Using Cuckoo Optimization and Firefly Algorithm
Mehdi Rezaei محمود قنبری -
Open Access Article
471 - Technical and Economic and Exergy Feasibility of Combined Production of Electricity and Hydrogen using Photovoltaic Energy
Nima Norouzi -
Open Access Article
472 - Evaluation of Accelerated Vehicles Retirement Program by Game Theory Approach
hosein sadeghi eghlim tamriAir pollution and high consumption of energy carriers have led to perform programs like accelerated vehicle retirement program by the government in recent years. In this study, the researchers have tried to examine this program by Game Theory approach. To achieve the go MoreAir pollution and high consumption of energy carriers have led to perform programs like accelerated vehicle retirement program by the government in recent years. In this study, the researchers have tried to examine this program by Game Theory approach. To achieve the goal, firstly, a static game with complete information is planned by three players involving automaker, transportation and fuel staff and old cars owners. Then, by removing the automaker, the game will be continued by two players through specific strategies for each player. Then, by using existing data of the year 2012, the game is re-written by two players. At the balance of three players, old car owners and automakers tend to retire their old vehicle, but the amount of the facilities and cash payments for this program are low. By removing automaker, the balance happens where the car owners tend to retire their old cars and to implement the project, whereas the credits provided by the government is low. Due to the quick increase of car prices, the authorities must pay attention to develop more facilities for the complete success of the program. Manuscript profile -
Open Access Article
473 - The effect of eight weeks of resistance training after transplantation of stem cells derived from adipose tissue on some apoptotic and anti-apoptotic factors of heart tissue in non-alcoholic fatty liver model rats
Erfan Gholami Seyed Abdollah Hashemvarzi Seyedeh Yasaman AsadiIntroduction: Nonalcoholic fatty liver disease is one of the most common chronic hepatic diseases which may be associated with cardiovascular disease. The study was conducted with the aim of investigating the effect of eight weeks of resistance training after stem cell MoreIntroduction: Nonalcoholic fatty liver disease is one of the most common chronic hepatic diseases which may be associated with cardiovascular disease. The study was conducted with the aim of investigating the effect of eight weeks of resistance training after stem cell transplantation in fatty liver model rats. Methods: 36 rats were divided into two groups: control (6 rats) and patients with fatty liver (30 rats). The control group used standard food for 6 weeks, while the animals in the diseased groups used high-fat food to induce fatty liver disease. At the end of the sixth week, to confirm the development of fatty liver disease, blood was randomly drawn from the tails of 3 rats. Then the animals of the patient group were randomly divided into 5 groups Saline, Fatty liver, Exercise, Cell, Exercise + Cell. About 1.5 x 106 stem cells for each mouse were injected into the cell receiving groups through the tail vein. The training program consisted of 8 weeks of climbing the ladder. Results: The amounts of Bax and Bcl-2 of the heart tissue decreased and increased respectively in the treated groups compared to the patient group, but these changes were significant only in the exercise group and exercise + cells compared to the patient group. Conclusion: Non-alcoholic fatty liver disease is significantly associated with cardiac cell apoptosis. Resistance training after stem cell transplantation decreased the Bax and increased the Bcl-2 in heart tissue. Therefore, it seems that this method can be considered as a therapeutic solution. Manuscript profile -
Open Access Article
474 - Impact of FSP Tool Probe Shape on Reinforcing Particles Dispersion in the Piston Alloy Using CEL Approach
Mostafa Akbari Hossein Rahimi Asiabaraki Ezatollah Hassanzadeh -
Open Access Article
475 - Colloids: Applications and Remaining Challenges
Majid Molaie -
Open Access Article
476 - Scheduling Problem of Virtual Cellular Manufacturing Systems (VCMS); Using Simulated Annealing and Genetic Algorithm based Heuristics
Saeed Taouji Hassanpour Reza Bashirzadeh Abolfazl Adressi Behnam Bahmankhah -
Open Access Article
477 - A Comparison of Job-Shop and Group Technology Using Simulation by ARENA
Siyavash Khaledan Hadi Shirouyehzad -
Open Access Article
478 - Analysis of Unbalanced Photovoltaic Systems Generation on Four-Wire Unbalance Distribution System of Shiraz
Hossein Karimianfard Hossein HaghighatThe use of distributed energy resources in power grids and in particular in the distribution system has gained noticeable popularity and growth in recent years. Given the increasing use of solar energy resources in low voltage grids, an appropriate strategy to coordinat MoreThe use of distributed energy resources in power grids and in particular in the distribution system has gained noticeable popularity and growth in recent years. Given the increasing use of solar energy resources in low voltage grids, an appropriate strategy to coordinate and control these resources is necessary in order to reduce annual grid energy losses and improve grid voltage profiles. In this paper, the optimization and coordination of local photovoltaic resources in a four-wire unbalanced low voltage distribution network is proposed and investigated for a given time horizon. The simulation is performed on a part of Shiraz low voltage network. Two scenarios are investigated: in the first scenario balanced output of three phase energy resources which are dispersed and uncontrolled, is considered. In the second scenario a situation is analyzed in which the output levels of these resources are unbalanced. The effect of these two scenarios on the annual energy losses of the network in question is thoroughly examined and discussed Manuscript profile -
Open Access Article
479 - Optimal Control of Micro-grid (MG) to Improve Voltage Profile Including Combined Heat and Power System
Hesam RahbarimaghamUsually, in the studies of optimal control for the micro-grid with combined heat and power (CHP), economic and environmental goals have been raised. In these studies, the optimization of control devices and compensators that are aimed at improving the technical aspects MoreUsually, in the studies of optimal control for the micro-grid with combined heat and power (CHP), economic and environmental goals have been raised. In these studies, the optimization of control devices and compensators that are aimed at improving the technical aspects of micro-grid has not been considered. Therefore, in this paper, these goals are considered simultaneously. In this paper the shunt capacitor, shunt reactor, static var compensator, load ratio control transformer, step voltage regulator and power generation of DGs are investigated as control variables with the aim of considering costs, losses and voltage profile improvement. The case under study is a distribution test system including 22 buses, which consists of photovoltaic and fuel cell. All network data is extracted from a real system. As a result, the system can completely represent a real system. In order to complete the study of the system, the emissions of fuel cells are considered in the objective function. The efficiency and output electrical and thermal power of the fuel cell are considered related to part load ratio as a real standard model introduced in previous studies. Manuscript profile -
Open Access Article
480 - A New 2-input CNTFET-Based XOR Cell With Ultra-Low Leakage Power For Low-Voltage and Low-Power Full Adders
Amir Baghi Rahin Vahid Baghi RahinThe XOR gate is one of the basic building blocks in the Full Adder (FA) circuit, whose performance improvements can lead to improved Full Adder. For this purpose, in this paper, a new low voltage XOR cell based on Carbon Nanotube Field Effect Transistor (CNTFET) is prop MoreThe XOR gate is one of the basic building blocks in the Full Adder (FA) circuit, whose performance improvements can lead to improved Full Adder. For this purpose, in this paper, a new low voltage XOR cell based on Carbon Nanotube Field Effect Transistor (CNTFET) is proposed. The main design goals for this new circuit are low power dissipation, low leakage current and full voltage swing at a low supply voltage (Vdd = 0.5 V). Several XOR circuits were completely simulated using HSPICE with 32nm CMOS and 32nm CNTFET technologies at a low supply voltage. The proposed XOR circuit is compared with the previously known circuits and its outstanding performance is shown. Simulations show that the new low voltage XOR has lower power dissipation, less leakage current and lower PDP than other XOR circuits, and is resistant to process variations. Based on the results obtained at Vdd=0.5 V ,frequency=250 MHz and Cload=3.5 fF, the proposed XOR shows propagation delay of 149.05 ps, power consumption of 716.72 pW, leakage power of 25.1 pW and PDP of 10.683x10-21 J. The proposed XOR can be used well in low voltage and low power Full Adder circuits. Manuscript profile -
Open Access Article
481 - Increased Light Absorption in CIGS Solar Cells with Plasmonic Ag Nanostructures to Increase Efficiency
Seyed Mohammad Sadegh Hsheminassab Mohsen Imanieh Abbas Kamali Seyyed ali Emamghorashi Saeed HassanhasseiniRecently, environmental problems on a global scale has been increased seriously. To overcome these problems, Solar cells is important as an energy source and free from contamination. Due to the increasing use of renewables, the use of solar cells for obtaining energy is MoreRecently, environmental problems on a global scale has been increased seriously. To overcome these problems, Solar cells is important as an energy source and free from contamination. Due to the increasing use of renewables, the use of solar cells for obtaining energy is growing. The cells convert directly sunlight into electricity by the photovoltaic. Photovoltaic energy research and development is generally done in two areas: cost reduction and increasing efficiency. The efficiency of thin film solar cells canbe increased considerably by coupling the solarcells with plasmonic nanoparticles (NPs). this study investigates, through meticuloussimulations, the effects of plasmonic nanoparticle shapes and size on theimprovement of the energy conversion efficiency of CIGS solar cells. Two different shapes including spheres and cylinders were analyzed in this study.It was revealed that the cylindrical Agnanoparticles, of diameter 50 nm, height 125 nm place on an array with period 215 nm exhibited the most substantialenhancement in the optical absorption and electrical currentgeneration. The conclusion attained in this paper has been made throughoptical and electricalanalysis as well as near field imaging studies. Manuscript profile -
Open Access Article
482 - Investigation of Using Anti-Reflecting Coatings in CZTS Solar Cells to Enhance the Light Absorption: Optimization by FDTD Method
Mina Mirzaei Javas Hasanzadeh Ali Abdolahzadeh Ziabari Mehdi MirzaeiIn the few past years, Solar cells based on Cu2ZnSnS4 (CZTS) are very promising thin-film solar cells due to their appropriate absorption coefficient and optical band gap, low-cost, non-radioactive and environmental friendly behavior. However, CZTS devices show poor eff MoreIn the few past years, Solar cells based on Cu2ZnSnS4 (CZTS) are very promising thin-film solar cells due to their appropriate absorption coefficient and optical band gap, low-cost, non-radioactive and environmental friendly behavior. However, CZTS devices show poor efficiency and identifying deficiencies and making improvements is necessary. In the present study, various anti-reflection coatings at the top surface of the solar cell were proposed. Minimization of the reflectance is carried out to optimize the thickness of ARC layers using Lumerical software. The density of the short-circuit photocurrent increases from 18.4 mA.cm−2 for solar cells without an antireflection coating to 36 mA.cm−2 for those with MgF2 layer coating. Manuscript profile -
Open Access Article
483 - Design and Simulation of 4 Transistors and 2 Memristors Memory with the Least Power and Power-Delay Product
Keramat Karami Sayed Mohammad Ali Zanjani Mehdi DolatshahiMemristor, as a fundamental element of SRAM and DRAM memories, can effectively reduce startup time and power consumption of the circuits. Non-volatility, high density of the final circuit, and reduction of power delay product (PDP) are some of the significant facts of m MoreMemristor, as a fundamental element of SRAM and DRAM memories, can effectively reduce startup time and power consumption of the circuits. Non-volatility, high density of the final circuit, and reduction of power delay product (PDP) are some of the significant facts of memristor circuits, which has led to the suggestion of a memory cell including and four transistors and two memristors (4T2M) in this paper. In order to simulate the proposed memory cell, the length of memristors has been selected 10 nm, and their on/off state resistors have been selected 250 Ω and 10 KΩ respectively. In addition, the proposed memory cell MOS transistors are simulated by the 32 nm CMOS PTM model. Simulation in the HSPICE software with 1V supply voltage and comparison with two conventional six-transistor (6T) and two transistors-two memory (2T2M) cells show that the use of memristors has made the proposed memory cell and 2T2M cell non-volatile. Moreover, the power consumption of the proposed circuit has decreased by 99.8% and 57.2%, compared to the previous two circuits respectively, and the power average delay product has also improved by 99.4% and 26.7%, respectively; however, the writing delay of this cell and 2T2M cell increased by 400% and 218% compared to 6T cell, respectively. Manuscript profile -
Open Access Article
484 - Improving the Performance of Cadmium Telluride-Based Solar Cells Using ZnCdS/NiO and ZnO Compounds for ETL/HTL and TCO Layers
Ebrahim Amoupour Javad Hasanzadeh Ali Abdolahzadeh Ziabari Peyman AzimiCadmium telluride (CdTe) solar cell is known for its high efficiency, low cost and high stability. In this paper, simulation of CdTe based solar cell (ZnO/ZnCdS/CdTe/NiO/Al) has been presented. ZnCdS, NiO and ZnO layers have been used as electron/hole transport layer (E MoreCadmium telluride (CdTe) solar cell is known for its high efficiency, low cost and high stability. In this paper, simulation of CdTe based solar cell (ZnO/ZnCdS/CdTe/NiO/Al) has been presented. ZnCdS, NiO and ZnO layers have been used as electron/hole transport layer (ETL/HTL) and transparent conductive oxide (TCO) layer, respectively. SCAPS-1D simulation software was used to evaluate the performance of the modelled multijunction CdTe solar cell. This software is capable of analyzing the efficiency with different parameters of cadmium telluride solar cell. The impact of thickness, carrier concentration, defect density of the CdTe, and ZnCdS/ CdTe interface defect density on the solar cell performance was also investigated. The optimized solar cell demonstrated a maximum power conversion efficiency (PCE) of 26.3 % with open circuit voltage (VOC) of 1.095 V, short circuit current density (JSC) of 27.22 mA/cm2 and FF of 88.14 % that shows huge promise in low-cost solar energy harvesting. Manuscript profile -
Open Access Article
485 - Design of a Dual-Beam End-Fire Antenna using the proposed Metamaterial Structure for 60 GHz MIMO Applications
Narges Malekpour Mohammad Amin HonarvarIn this paper, a dual-beam end-fire Bow-tie antenna for millimeter-wave applications over 57–64 GHz is designed. By introducing a new structure in the decoration of metamaterial slabs in the horizontal plane of the Bowtie antenna, a dual-beam generated at 60° MoreIn this paper, a dual-beam end-fire Bow-tie antenna for millimeter-wave applications over 57–64 GHz is designed. By introducing a new structure in the decoration of metamaterial slabs in the horizontal plane of the Bowtie antenna, a dual-beam generated at 60° and 120°. The proposed antenna is composed of a 2×3 array of metamaterial unit cells, which leads to a considerable gain enhancement and generates a dual-beam pattern. To create a dual-beam in the E-plane, the array of metamaterial slabs integrated vertically in front of the Bowtie antenna and tilted by 15o with regard to the antenna axis to tailor the radiation beam. These unit cells are capable of creating two resonances that can play an important role to improve the gain in a wide frequency band. The resulting dual-beam radiation in the E-plane has maxima at +60 and 120 degrees with a maximum peak gain of 9.5 dBi at 60 GHz. The final design simulated with a parametric study, and the best configuration provided despite the maintenance of other radiation characteristics of the antenna.Keywords: End-Fire Antenna, dual-beam Antenna, ENZ Metamaterial unit-cell, Millimeter-Wave, High-Gain Antenna. Manuscript profile -
Open Access Article
486 - Introducing an Innovative D Flip-Flop for Designing Quaternary QCA Register
Alireza Navidi Reza Sabbaghi-Nadooshan Massoud DoustiTaking advantage of advances in Nanotechnology, the quantum-dot cellular automata (QCA) has overcome many limitations that complementary metal-oxide-semiconductor (CMOS) had been confronted. Undesirable characteristics such as too many leakage currents limit the CMOS de MoreTaking advantage of advances in Nanotechnology, the quantum-dot cellular automata (QCA) has overcome many limitations that complementary metal-oxide-semiconductor (CMOS) had been confronted. Undesirable characteristics such as too many leakage currents limit the CMOS designs in nano dimensions. The idea of designing multiple-valued logic (MVL) systems rather than standard binary has gotten attractive to many designers. The application of MVL in the design of digital circuits offers so many advantages over traditional methods. D flip-flop is a primary sequential circuit in any register. In this paper, a novel quaternary D flip-flop based on introducing quaternary QCA (QQCA) is presented. The structure of our quaternary model is clarified. Also, we have proposed a 4-qubits register by utilizing the presented quaternary D flip-flop. Both circuits got simulated and evaluated by QCASim (quaternary edition). QCASim can illustrate the simulation result in a truth table and a waveform format. Our work got compared with other published works. The simulation results show that our proposed circuit is efficient in terms of latency and energy consumption. Manuscript profile -
Open Access Article
487 - Design of a High Step-up DC-DC Converter Based on QZSI with Low Voltage Dtress by Using Coupled Inductor Technique
Jafari Hosein Mahdi Shaneh Tohid NouriHigh step-up structures are commonly used to upgrade the low voltage levels generated by renewable energy sources. In this paper, a high step-up structure based on Quasi Z-Source network is presented, which has a simple yet functional structure consisting of two inducto MoreHigh step-up structures are commonly used to upgrade the low voltage levels generated by renewable energy sources. In this paper, a high step-up structure based on Quasi Z-Source network is presented, which has a simple yet functional structure consisting of two inductors and two capacitors. Due to the duty cycle of about 50% for this converter, the problems of reverse recovery of diodes and stability are solved. In addition, the common ground of the power switch and the input source simplifies the control circuit. Using the coupled inductor technique as well as the voltage multiplier cell, the converter voltage gain increases significantly. In addition, the stacked capacitor is used to limit the voltage stress on the switch. The use of the proposed structure increases the voltage gain of the converter. The proposed structure also reduces the level of voltage stress on the semiconductors of the circuit, which reduces the cost and increases the efficiency of the circuit. The converter designed with 25V/ 400V input/ output 100Wouput power is simulated in PSpice software and the results are presented. Manuscript profile -
Open Access Article
488 - Effective Visual Saliency Detection Method Using Reduced Color and Texture Features
Masoud khazaee Fadafen Naser Mehrshad Seyyed Mohammad RazaviIn this study, an effective and efficient algorithm for detection a saliency map is presented based on the modeling of the rapid response of the human visual system to changes in the intensity, texture and color. Some cases such as inspiration from performance of human MoreIn this study, an effective and efficient algorithm for detection a saliency map is presented based on the modeling of the rapid response of the human visual system to changes in the intensity, texture and color. Some cases such as inspiration from performance of human visual system, requiring no training, reduce number of image colors, reduce color channels and Proper use of the least texture information in this algorithm have increased its efficiency. In the proposed method in the first step , Due to sensitivity of the human visual system to higher contrast signals, only higher contrast channel has been used to extract the color saliency map, Then the intensity saliency map as well as the texture saliency map are extracted using the intensity component in lab color space using Simple cell computational model of the visual cortex and finally, with the perfect combination of the saliency maps of the color, the intensity, and the texture, object saliency map is obtained. The proposed method and existing methods have been tested on MSRA10K and ECSSD databases. The results of the implementations show that the proposed hybrid algorithm for the detection saliency map using the dominant color and texture features, On the ECSSD database, the mean absolute error, F-measure score and the area under the ROC curve are 0.173, 0.789 and 0.891, respectively, and on the MSRA10K database are 0.178, 0.790 and 0.919, respectively, compared to other models, it indicates better performance of the proposed method than other methods. Manuscript profile -
Open Access Article
489 - Computational Circuit Design Using a New Seven-Input Majority Gate in Quantum-dot Cellular Automata
Farzaneh Jahanshahi Javaran Somayyeh Jafarali Jassbi Hossein Khademolhosseini Razieh FarazkishThe quantum-dot cellular automata (QCA) technology is a computational technology used to build nano-scale circuits. When the dimensions of the components decrease, the sensitivity of the circuit increases and the quantum circuits become more vulnerable to the occurrence MoreThe quantum-dot cellular automata (QCA) technology is a computational technology used to build nano-scale circuits. When the dimensions of the components decrease, the sensitivity of the circuit increases and the quantum circuits become more vulnerable to the occurrence of defects and radiation in the environment. The two major gates in this technology are inverter and majority gates, and most circuits are built based on these two gates. This paper aimed to design a seven-input majority gate in quantum-dot cellular automata by imposing low overhead on the circuit. Using a majority gate with more inputs reduces cell count, latency, and complexity in the QCA circuit. However, perhaps the need to use the seven-input gate is not yet felt we then design and implement a number of logic circuits. A new 7-input majority gate is designed in this paper, with 19 cells. The proposed structure is single-layer with an occupied area of 24564 nm2 that produces the correct output in one clock phase, then a four-input AND gate, a four-input OR gate, a two-input XOR gate, a two-input XNOR, a three-input XOR gate and a full adder are implemented using the designed seven-input gate. Including all multi-bit full adders, using the proposed seven-input gate. The proposed full adder is designed by the seven-input majority gate proposed and a fault-tolerant three-input majority gate. Therefore, it can be said that the designed full adder is somewhat tolerable, that means, it is somewhat tolerable against the fault that occur in this technology. QCAPro software is used to analyze the energy consumption of the recommended structure. Then, the circuit performance is evaluated using QCADesigner 2.0.3 simulator software for quantum-dot cellular automata. Manuscript profile -
Open Access Article
490 - Designing a New Gate-Diffusion Input in Quantum-Dot Cellular Automata Technology
Hamidreza Sadrarhamii Sayed Mohammadali Zanjani Mehdi Dolatshahi Behrang BarekatainQuantum-dot cellular automata (QCA) is a modern technology, which has higher speed, lower power consumption, higher density, and lower complexity than conventional technologies, such as CMOS. Moreover, the gate diffusion input (GDI) technique has been successful in redu MoreQuantum-dot cellular automata (QCA) is a modern technology, which has higher speed, lower power consumption, higher density, and lower complexity than conventional technologies, such as CMOS. Moreover, the gate diffusion input (GDI) technique has been successful in reducing complexity, area, and energy consumption in low-power circuit designs. In this technique, a wide range of complex logic functions can be implemented using only two transistors as the main block. In this study, a QCA-based GDI block is proposed using only 11 cells as a standard design unit that can be used to implement basic functions such as AND, OR, MUX, BUFFER, NOT and XOR in digital circuits. QCADesigner simulations of the functions in 18 nm technology indicate the superior performance of the proposed block with only one clock cycle delay in performing the operations. Moreover, the power consumption analysis of the designed circuits is performed using QCADesigner. The advantages of the proposed circuit compared to previous designs are 31% reduction in cell count, 50% smaller surface area, and 17% reduction in total energy loss. Manuscript profile -
Open Access Article
491 - Design and Implementation of Soft Switching Three-port High Step-Up DC-DC Converter for Solar Energy Applications
Somaye Gashtasebi Fariborz Haghighatdar Fesharaki Seyed Mohammad Mehdi MirtalaeiIn recent few decades, due to various reasons, including energy crisis and environmental problems, renewable energy sources such as wind energy, solar systems and fuel cells have received much attention. Solar or photovoltaic systems are one of the most widely used rene MoreIn recent few decades, due to various reasons, including energy crisis and environmental problems, renewable energy sources such as wind energy, solar systems and fuel cells have received much attention. Solar or photovoltaic systems are one of the most widely used renewable energy sources that have a low output voltage. For this reason, research on dc-dc converters has increased in recent years. In this paper, a non-isolated high voltage gain converter with three input-output ports is proposed. This converter provides two separate paths for power flow from each input source to the output load. In order to reduce the number of converter components, some components play multiple roles. Therefore, the energy storage device (battery) will charge with the same components used to transfer the power to the load. In this converter, to increase the voltage gain, the coupled inductor technique is used. Moreover, to reduce the leakage inductance as well as achieving the soft switching condition, two active clamps are used. Since the voltage across the switches is limited, the switches can be used with low voltage stress and thus low conduction losses. In this converter, the ripple of the input current will reduce by adding an inductor at its input. This has a significant impact on the performance and the lifespan of the solar cells. The various operational modes of the converter are discussed and the designing considerations are presented. A prototype of the proposed converter is simulated to supply a 130 W, 330 V load with a switching frequency of 50 kHz, in OrCAD software. Finally, a laboratory sample is implemented and the theoretical analysis are validated by the practical results. Manuscript profile -
Open Access Article
492 - Design and Simulation of a New Optimized Full-Adder Using Carbon Nano Tube Technology
Abbas Asadi Aghbolaghi Mehran EmadiThe full adder circuit is one of the most significant and prominent fundamental parts in digital processors and integrated circuits since it can be used for implementing all four basic computational functions including: addition, subtraction, multiplication, and divisio MoreThe full adder circuit is one of the most significant and prominent fundamental parts in digital processors and integrated circuits since it can be used for implementing all four basic computational functions including: addition, subtraction, multiplication, and division. so, in this paper a new low power and high performance full adder cell has been proposed with the benefit of using carbon nano tube field effect transistors. The proposed design contains 12 CNTFET transistors which are connected in pass transistor logic style to make the desired functionality. Carbon Nano Tube Field Effect Transistor (CNTFET) has modified electrical characteristics such as low power consumption and high speed in comparison with MOSFET transistor; The proposed design is simulated using Hspice software based on CNTFET model and 0.65V supply voltage. the simulations are done considering three different frequencies, and three different load capacitors. The simulation results, which demonstrated in tables and diagrams, proved the superiority of proposed design in terms of power consumption and performance (PDP) compared to the existing counterparts. Manuscript profile -
Open Access Article
493 - Fuzzy Control of Polymer Fuel Cell for Attract Maximum Power
Zahra Nejati Farid Sheikholeslam Hamid MahmoodianPolymer fuel cell is one of the most attractive of fuel cell from point of the design and operation and also in comparison with other types of fuel cell, for a weight and size, polymer fuel cell produces more power. But however, one of the problems to use of this system MorePolymer fuel cell is one of the most attractive of fuel cell from point of the design and operation and also in comparison with other types of fuel cell, for a weight and size, polymer fuel cell produces more power. But however, one of the problems to use of this system is its low efficiency .To overcome the low efficiency of the fuel cell polymer in this paper is tried to used from maximum power point tracking. According to the characteristic of the flow –power the fuel cell, which is a non-linear curve and has a maximum point and use of the fuzzy controller and the proper selection of input and output membership functions trying to the System always works at maximum power. For this purpose, a chopper is used between the fuel cell and the load and to adjust the duty cycle of the applied signal to it is applied the fuzzy-TSK type controller that Its inputs are stream slope and slope changes. The results show that this controller has a good performance and that is faster compared with the perturbation and observation method. Manuscript profile -
Open Access Article
494 - Hardware Implementation of LMS-Based Adaptive Noise Cancellation Core with Low Resource Utilization
Omid Sharifi Tehrani Mohsen Ashorian Payman Moallem A hardware implementation of adaptive noise cancellation (ANC) core is proposed. Adaptive filters are widely used in different applications such as adaptive noise cancellation, prediction, equalization, inverse modeling and system identification. FIR adaptive filt More A hardware implementation of adaptive noise cancellation (ANC) core is proposed. Adaptive filters are widely used in different applications such as adaptive noise cancellation, prediction, equalization, inverse modeling and system identification. FIR adaptive filters are mostly used because of their low computation costs and their linear phase. Least mean squared algorithm (LMS) is used to train FIR adaptive filter weights. Advances in semiconductor technology especially in digital signal processors (DSP) and field programmable gate arrays (FPGA) with hundreds of mega hertz in speed, will allow digital designers to embed essential digital signal processing units in small chips. But designing a synthesizable core on an FPGA is not always as simple as DSP chips due to complexity and limitations of FPGAs. In this paper we design anLMS-based FIR adaptive filter for adaptive noise cancellation based on VHDL97 hardware description language (HDL) and Xilinx SPARTAN3E (XC3S500E) which utilizes low resources and is high performance and FPGA-brand independent so can be implemented on different FPGA brands (Xilinx, ALTERA, ACTEL). Simulations are done in MODELSIM and MATLAB and implementation is done with Xilinx ISE. Finally, result are compared with other papers for better judgment. Manuscript profile -
Open Access Article
495 - Effects of Pimpinella saxifraga L. extracts on environmental isolates of Enterococcus faecalis and HeLa cell line
Fatemeh Shams Moattar Mirsassan Mirpour Naghmeh HemmatiPimpinella saxifraga L. is a genus of aromatic plants native to northern Iran. Some of its medicinal benefits are already known. The purpose of this study is to investigate the effect of Pimpinella saxifraga L. plant extract on some environmental isolates of Enterococcu MorePimpinella saxifraga L. is a genus of aromatic plants native to northern Iran. Some of its medicinal benefits are already known. The purpose of this study is to investigate the effect of Pimpinella saxifraga L. plant extract on some environmental isolates of Enterococcus faecalis and the HeLa cell line. After collecting the plant and drying it, methanolic and aqueous extracts were prepared. Since phenolic compounds have multiple effects, the number of phenolic compounds in the methanolic extract was measured by the Folin-ciocalteu method. Antibacterial activity against E. faecalis was first measured by disk diffusion, and then MIC and MBC were measured by the Microdilution method. Finally, the anti-proliferative activity of plant extracts on the cervical cancer cell line (HeLa) was investigated using the MTT method. The volume of phenolic compounds in the methanolic extract was 968.33 mg/ml. The investigation of the antimicrobial effect showed that the methanolic extract has significant effects against E. faecalis. The MIC and MBC of this extract were 25 and 100 mg/ml, respectively, and the growth of the cervical cancer cell line (HeLa) was inhibited by about 13% by using MIC concentration. The results of the experiments demonstrated that the methanolic extract of P. saxifraga L. has an inhibitory effect on the growth and proliferation of Enterococcus faecalis and the HeLa cell line. Manuscript profile -
Open Access Article
496 - Comparison of exploitation criteria and acceleration of diagrid steel structures with tube system based on wind dynamic analysis
mehdi hooshmand Hassan Haji Kazemi Seyed Alireza ZareeiConsidering the widespread use of diagrid systems in high-rise buildings, it seems necessary to investigate the behavior of this structural system against the wind and control comfort criteria based on acceleration. The purpose of this research is to compare the comfort MoreConsidering the widespread use of diagrid systems in high-rise buildings, it seems necessary to investigate the behavior of this structural system against the wind and control comfort criteria based on acceleration. The purpose of this research is to compare the comfort criterion based on acceleration in the diagrid system with the tube system. For this purpose, the effect of various parameters such as the acceleration of floors and base shear under dynamic wind load has been evaluated. It is expected that the performance of the diagonal network will be evaluated with a more detailed understanding of the diagonal network in tall structures and the evaluation of the performance and comfort criteria based on the acceleration against the wind load using the dynamic analysis of time history using Cholsky, ergodic and AP methods. Investigations show that the acceleration of the diagrid system floors, based on the ASCE7 wind dynamic response prediction equations, has exceeded the permissible limit of the ASCE 7 regulation of milli-g20. This article is due to the overestimation of ASCE 7 equations compared to the results of wind time history analysis. So, in the 50-story structure, the maximum acceleration of the roof obtained from the ASCE equation is 71.83 times the results of the dynamic analysis of wind time history, and in the 70-story structure, it is 2 times, and in the 100-story structure, it is 1.87 times the results of the dynamic analysis of the wind time history. Manuscript profile -
Open Access Article
497 - Evaluation of the Peak Ground Acceleration on Seismic Characteristic of Critical Slice Surface on Embankment dams
Mehdi ShirdelAbstract: Usually, safety of slip surfaces in embankment dams have been evaluated with 2 methods: peak ground acceleration increasing method and stuff resistance decreasing method are 2 main methods for evaluation of critical bound. In this research, peak ground accele MoreAbstract: Usually, safety of slip surfaces in embankment dams have been evaluated with 2 methods: peak ground acceleration increasing method and stuff resistance decreasing method are 2 main methods for evaluation of critical bound. In this research, peak ground acceleration increasing method has been used to evaluate stability safety of slip surfaces. In this method, peak ground acceleration has been increased to receiving critical bounds for parameters in time domain (for example permanent deformation, equal dynamic factor of safety, and minimum dynamic factor of safety). To evaluate the effect of this parameter, Masjed Soleiman dam has been selected for a case study. 10 Finite Element model of Masjed Soleiman dam has been constructed considering the Mohr-Coulomb failure criterion for the body of the dam. The 2 earthquake records have been applied horizontally to the bedrock as the input for dynamic analysis without any change in frequency content. Results show that, in critical sliding surface on downstream, with increasing of peak ground acceleration, equal dynamic factor of safety decreased but changing of minimum dynamic factor of safety and permanent deformation have meaningful process. Manuscript profile -
Open Access Article
498 - Comparison of Exploitation Criteria and Acceleration of Long Diagrid Steel Structures with Environmental Frame System Based on Dynamic Wind Analysis
mehdi hooshmand Hassan Haji Kazemi Seyed Alireza ZareeiConsidering the widespread use of diagrid systems in tall buildings, it is necessary to investigate the behavior of this structural system against the wind and control comfort criteria based on acceleration. According to different regulations, it is evident that there i MoreConsidering the widespread use of diagrid systems in tall buildings, it is necessary to investigate the behavior of this structural system against the wind and control comfort criteria based on acceleration. According to different regulations, it is evident that there is not much guidance for the design of this structural system and its requirements have not yet been included in the design regulations. Therefore, one of the most important goals of the current research is to investigate and use the Diagrid structural system as one of the modern structural systems in high-rise buildings. Another goal of this research is to compare the performance of the diagrid system with the environmental pipe system. Accordingly, the effect of various parameters including the acceleration of floors and shear of the base under dynamic wind load has been evaluated. It is expected that the performance of the diagonal network will be evaluated with a more detailed understanding of the diagonal network in tall structures and the evaluation of the operation and comfort criteria based on the acceleration against the wind load using dynamic time history analysis applying Cholesky, ergodic and AP methods. The results have been compared with the formulas of the ASCE7 regulation and the AIJ-GBV-2004 and ISO 10137:2007 comfort criteria and the National Building Code of Canada (NBCC). These investigations indicate that the acceleration of the diagrid system floors based on ASCE7 wind dynamic response prediction equations, has exceeded the permissible limit of ASCE 7 regulation by 20 milli-g (20Gal). This is due to the high estimation of ASCE 7 equations compared to the results of wind time history analysis. In such a way that in the 50-, 70-, and 100-story buildings, the maximum accelerations of the roof obtained from the ASCE 7 equation are 1.83, 2.07, and 1.87 times the results of the dynamic analysis of wind time history, respectively. Manuscript profile -
Open Access Article
499 - Production of Synthetic Seismic Records Using Fuzzy Neural Network
Peyman Shadman Mehdi Amri Mohammad KhorasaniThere is a growing need for dynamic time history analysis and the absence of proper records in different areas has necessitatedthe production of artificiallaccelerograms compatible with the whole plan. This study presents a new approachbased on wavelet packet transform MoreThere is a growing need for dynamic time history analysis and the absence of proper records in different areas has necessitatedthe production of artificiallaccelerograms compatible with the whole plan. This study presents a new approachbased on wavelet packet transform and artificial intelligence techniques to produce artificial earthquake accelerograms compatible with the whole plan. This approachtakes into account the magnitude and the distance from the fault. The study of neural networks and fuzzy wavelet packet analysis has been used to achieve the desired goal. To do so, first earthquake accelerograms have been collected according to specific site conditions, earthquake magnitude and distance from origin.Then all records have been gatehered for training with fuzzy neural network. Attenuation spectra have been developed on the basis of information in the area using nonlinear regression. Then using fuzzy neural networks, the relationship between earthquake records and the devloped spectra from each record is calculated. In this satge, using wavelet packet analysis, mapping acceleration are analyzed and converted intoaccelerograms (wavelet coefficients) Manuscript profile -
Open Access Article
500 - A study on the flexural behavior of fiber-reinforced concrete beams subjected to tensile steel corrosion
iman sadrinejadThis paper presents the results of an experimental study on the flexural performance of reinforced concrete beams made of fibrous concrete under the corrosion of tensile steels. Fifteen reinforced concrete beams were prepared in three groups; in two groups, two types of MoreThis paper presents the results of an experimental study on the flexural performance of reinforced concrete beams made of fibrous concrete under the corrosion of tensile steels. Fifteen reinforced concrete beams were prepared in three groups; in two groups, two types of steel and polyolefin fibers were utilized to construct the beams. Four beams from each group were subjected to accelerated corrosion to create corrosion percentages of 3.5, 7, 15 and 30% in tensile steels. Then the beams were subjected to a four-point bending test, and the parameters of yield strength, ultimate strength, yield deflection, ultimate deflection, failure mode and ductility of the beams were investigated. The results indicated that up to the corrosion level of 15%, with the development of general corrosion, along with the reduction of stiffness and resistance of the beams, the ultimate deflection of the beams increased, and at the corrosion level of 30%, with the development of local corrosion, the ultimate strength and ultimate deflection of the beams were greatly reduced. The level of corrosion in tensile steel of beams containing steel fibers was lower than that of in the other beams, which was caused by the sacrificial anode effect of steel fibers. Under the corrosion conditions of tensile steel, the reduction of strength and stiffness in fibrous concrete beams were less than those in the plain concrete beams, and the performance of steel fibers in this field was significantly better than their polyolefin counterparts. Furthermore, the fibers used for this purpose, had significantly positive effect on the ductility of reinforced concrete beams with tensile steel corrosion. Manuscript profile -
Open Access Article
501 - Cellulose nanocrystal functionalized palladium nanoparticles as an efficient heterogeneous catalyst for the synthesis of α-amino nitriles via Strecker reaction
Atieh Mirosanloo Daryoush Zareyee Mohammad Khalilzadeh -
Open Access Article
502 - Evolution Trends of Cell Phone Usage in Primary School Students
Morteza ManteghiThe goal of this research was to investigate the evolution trend of cell phone usage in primary school children. The research method was qualitative and the type was grounded theory. The study sample included 115 girl and boy cell phone users who studied from 1st to 6th MoreThe goal of this research was to investigate the evolution trend of cell phone usage in primary school children. The research method was qualitative and the type was grounded theory. The study sample included 115 girl and boy cell phone users who studied from 1st to 6th grade in primary school. The sampling of the research was purposeful. The results of the study indicated that girl and boy cell phone users at early grades of primary school, after getting acquainted with some features of cell phones (like communications, entertainment, education and services) use it positively. But at higher grades of primary school, due to lack of necessary cultural grounding in society, school and family for proper usage of cell phones, the application of cell phones gradually drifts towards improper usages (like time wasting, call disturbing, malignity, snobbery, facilitation of girls and boys relationships, SMS loves, call credit exploitation, playing with Bluetooth, disclosure of individuals' private information, improper or pornography photos and videos applications, electronic aggression, finding hidden identity, identity disorientation, and cell phone addiction). Therefore, to avoid these issues, it is necessary for cultural and educational authorities and students’ parents to make a big effort for cultural grounding for proper and useful application of cell phones. Manuscript profile -
Open Access Article
503 - The feasibility of accepting mobile education in higher education in terms of faculty members of Shahid Beheshti University
masomeh jeddizahedThe purpose of this study was to determine the feasibility of accepting mobile phone education in higher education for faculty members of Shahid Beheshti University. This research was applied in terms of purpose and in terms of data collection method, it was a descripti MoreThe purpose of this study was to determine the feasibility of accepting mobile phone education in higher education for faculty members of Shahid Beheshti University. This research was applied in terms of purpose and in terms of data collection method, it was a descriptive-survey study. A researcher-made questionnaire consisting of five components (usefulness, ease, self-efficacy, challenge, attribute) was used for collecting data. The validity of the questionnaire was verified by three experts and the reliability of the questionnaire was verified through a pilot study on a sample of 55 respondents and its value was calculated by Cronbach's alpha (94%), indicating high reliability The statistical population of the study was 841 faculty members of Shahid Beheshti University. 230 students were randomly selected through stratified sampling Also, in order to analyze the data, inferential statistical tests including one-sample T-test and multivariate analysis of variance analysis were used. Finally, the results of the study showed that acceptance of mobile phone education from The faculty members are in a good position and, according to professors, using mobile phones can increase their self-efficacy, but they find that the training is not in a good position and the use of mobile phone training is challenging. Also, faculty members' opinion about acceptance of mobile phone education showed that in general, there is no significant difference between the acceptance of mobile phone education between male and female teachers with different scientific degrees and backgrounds. Manuscript profile -
Open Access Article
504 - The Relationship between Internet and Cell-Phone Addictions and Academic Burnout in University Students
Elham Hosseinpour Ali Asgari Mohsen AyatiThe aim of this study was to investigate the relationship between Internet and cell-phone addictions and academic burnout in Birjand University students. The research method was a descriptive correlational. The research population included all the undergraduate students MoreThe aim of this study was to investigate the relationship between Internet and cell-phone addictions and academic burnout in Birjand University students. The research method was a descriptive correlational. The research population included all the undergraduate students of Birjand University (8591 people) studying during the academic year of 2014-15. Based on Krejcie and Morgan's table, 370 people were chosen as the research samples using a cluster sampling method. To collect the data, Young's Internet addiction questionnaire, Young-Koo's cell-phone addiction questionnaire, and Berso’s academic burnout questionnaire were used. For data analysis, Pearson's correlation and regression were applied. The results were indicative of a positive significant relationship between cell-phone and Internet addictions and academic burnout. Also the regression result revealed that Internet addiction was a predictor of academic burnout and cell-phone addiction was a predictor of academic exhaustion, cynicism, and inefficacy. Manuscript profile -
Open Access Article
505 - The Study of Cell Phone Use and its Relationship with Sleep Quality and Academic Performance of High School Students
Mohsen Fazlali Fereshteh FarshidiNowadays, it seems excessive use of electronic media causes sleep disorders and low academic performance in adolescents. The present study was conducted aimed to investigate the use of cell phone and its relationship with sleep quality and academic performance of second MoreNowadays, it seems excessive use of electronic media causes sleep disorders and low academic performance in adolescents. The present study was conducted aimed to investigate the use of cell phone and its relationship with sleep quality and academic performance of second year high school students. This study was a correlation one. The statistical population was all second year high school students studying in 2015 in district one in Sari. The sample was selected 300 subjects using simple random sampling based on Krejcie and Morgan table. The research instrument includes cell phone application test, Pittsburgh Sleep Quality questionnaire and students' average (GPA). Data were analyzed using Pearson correlation test and independent t-test. The findings showed that a significant relationship was found between the use of cell phone, sleep quality and academic performance of students who have cell phones, in a way that by increasing the use of cell phone among students their sleep disorders are increased and academic performance is reduced. Manuscript profile -
Open Access Article
506 - The Effect of Mobile-Based Arcade Games on Eye and Hand Coordination in Elementary Students
محسن باقری Seyed Roham YadeghariThe purpose of this study was to investigate the effect of mobile-based arcade games on the coordination of the eyes and hands of the first-grade students of the elementary school. The study is based on quasi-experimental method, using a pretest-posttest design with a c MoreThe purpose of this study was to investigate the effect of mobile-based arcade games on the coordination of the eyes and hands of the first-grade students of the elementary school. The study is based on quasi-experimental method, using a pretest-posttest design with a control group. Participants in this study were 48 female and male first-grade students of two elementary schools located in the Kermanshah in the academic year of 2019-2020, who were selected as convenience sampling method and randomly assigned into two groups of treatment (24 students) and control (24 students) in each school. The students of the treatment group played three kinds of arcade games for 6 weeks, including three 45-minute sessions in each week. For data gathering Frostig tests and Lincoln Oseretsky which respectively measure coordination of the eyes and hands were applied. For data analysis, repeated measure ANOVA was used. The results of the study show that cell phone-based arcade games have a significant effect on elementary students’ eye-hand coordination P ( Manuscript profile -
Open Access Article
507 - A Survey of Hidden Identity in Cellular Phone and Internet Users
Morteza Manteghi Ehsan DinparvarThe goal of this research was to investigate creating and deepening hidden and informal identity on students who are users of cellular phones and internet. The method of the research is a survey one. Statistical sample was 450 individuals including girl and boy students MoreThe goal of this research was to investigate creating and deepening hidden and informal identity on students who are users of cellular phones and internet. The method of the research is a survey one. Statistical sample was 450 individuals including girl and boy students of Kharazmi University whose age domain was among 18 to 25. They were selected through random sampling method. A questionnaire having been validated was done in spring 2012 on both male and female students. Data analysis was performed through SPSS software. The results showed that cellular phone and internet technology were effective in the formation of hidden and informal identity of users. Moreover, the amount of the information of the family of students on their way of using hidden features of cellular phone and internet was significantly lower than that of their close friends. The comparison between female and male students on using the hidden features of cellular phones and internets showed that female users welcome these features more significantly than male users. Manuscript profile -
Open Access Article
508 - Comparing Cell Phone-Based and Traditional Lecture-Based Teaching Methods' Effects on Agricultural Students' Learning
Abdolhamid Papzan Adel SulaimanyRegarding the increased speed of creating new knowledge and the development of communication technologies, like cell phone, which makes it possible the access to various unlimited resources and data in an unlimited time and place, and regarding many positive aspects of MoreRegarding the increased speed of creating new knowledge and the development of communication technologies, like cell phone, which makes it possible the access to various unlimited resources and data in an unlimited time and place, and regarding many positive aspects of applying it in schools and the necessity of adjusting with changes and the correct use of this new technology, the present research was conducted to examine the effect of teaching via cell phone on students learning in Khooshehaye Zarin agricultural school in Rawansar, Kermanshah province, and comparing it with traditional lecture method. In a semi-experimental research method, 30 male students were selected through random sampling method as the research sample, divided into two paired groups, 15 for experimental group and 15 for control group, based on age, educational status, previous grade point average and family economical status. Data collection tool was a 10 item test based on behavioral objectives. The experimental group was taught in two sessions of two hours through cell phone, and the control group was taught the same topic through traditional lecture method in exactly the same amount of time. Post–test was performed on two groups through the above-mentioned 10 item test and the results were analyzed through t test method. The results showed that teaching via cell phone has more effects on students learning compared with traditional lecture method. Manuscript profile -
Open Access Article
509 - A Study on the Frequency and Type of Using Cell-Phone by High School Students in Mazandaran Province
Ramezan Hasanzadeh Ali Lotfi Seyed Shamsolah Hoseyni Ahmad EbrahimiThis study aimed at the frequency and type of using cell-phone by high school students. The research method used was a descriptive-survey one. The statistical society included all the high school students in Mazandran in 2010-11 academic year. The sample was chosen thro MoreThis study aimed at the frequency and type of using cell-phone by high school students. The research method used was a descriptive-survey one. The statistical society included all the high school students in Mazandran in 2010-11 academic year. The sample was chosen through multi-stage stratified random sampling method and 383 subjects were selected based on Kerjecie and Morgan's Table. A researcher- made questionnaire was used for collecting data. The content validity of the questionnaire was confirmed by related experts and its reliability was calculated through Cronbach Alpha by SPSS software 0/80. Two statistical methods were use in analyzing the gathered data, namely, descriptive statistics including: frequency, standard deviation and mean along with inferential statistics including: independent t test. The results showed that majority of the students had a cell-phone and consider it as a necessary tool. The girls were reported to use cell-phone and its tools more than the boy students. However, boy students used it more than girls for educational and learning purposes. There was no significant difference between boys and girls in using cell-phone for the sake of fun and social interactions. Manuscript profile -
Open Access Article
510 - Evaluation of possibility of replacing nitrite and Ascorbic acid present sausage using celery powder and barberry juice During storage at 4 ° C
سید ابراهیم حسینی sanaz seifi nofersti mohamdreza khaniThe aim of this study is to introduce processed meat product in the way of minimizing the preservatives substances by using celery powder and barberry juice. In this experiment the production of sausage 55 is designed while substituting the nitrite level of 90, 60, and MoreThe aim of this study is to introduce processed meat product in the way of minimizing the preservatives substances by using celery powder and barberry juice. In this experiment the production of sausage 55 is designed while substituting the nitrite level of 90, 60, and 0 ppm respectively with level of 1, 2 and 4 percent of celery powder and level of 5 percent the mixture of ascorbic acid and barberry juice. The specifications of produced samples have been analyzed through chemical tests (Thiobarbituric acid, residual nitrite, color analysis, and peroxide values), microbiological analysis and sensory analysis in the 1st and the 21st day of production. The analysis of the sample corresponding with 1 percent celery powder and barberry juice resulted in the averages of 12.63 by red color index, 40.76 by residual nitrite, 4.06 by peroxide values, and 0.183 by thiobarbituric value; closed to the control in compare with other produced samples. Microbiological culture of mold and yeast and enterobacteriaceae within 21days confirmed the quality of substances and materials as well as the appropriate condition of production. Admittedly, taking the texture and color into account, the sense evaluation test shows the average of 4.5, compared to the other produced samples, which was closed to the control. According to the healthly benefits of herbal substances and as claimed by unhealthy specification of synthetic preservatives substances; the outcomes of this study confirms that partial replacement of nitrate with powdered celery and barberry juice, affecting the health value of processed meat product. Manuscript profile -
Open Access Article
511 - Review of Brucella contamination in Milk and its products of Iran
Amir Shakerian sahar nouri Mohammad NodargahBrucellosis or Malta-Fever, is a zoonotic disease that cause by gram negative brucella bacteria and is a serious health problem in the Mediterranean area. It usually transmitted to humans from livestock or tainted livestock products. Brucellosis in humans followed by co MoreBrucellosis or Malta-Fever, is a zoonotic disease that cause by gram negative brucella bacteria and is a serious health problem in the Mediterranean area. It usually transmitted to humans from livestock or tainted livestock products. Brucellosis in humans followed by consumption of raw milk, its products and soft cooked meat. It’s endemic as well as in our country and it has increased in recent years. Regarding the health of milk and its products due to the high value in humans food is paramount important and contamination of milk and its products from important ways of disease transferring, therefore in this article provides overview of dairy-products contamination as one the important transfer ways since 1948 to 2016. There are several methods to diagnose, but in recent years, according to the molecular methods such as PCR or serology ones as ELISA due to the sensitivity and a high degree of accuracy are payed attention. Prevention, control and eradicate program of brucellosis have been different according to the economic condition various in countries and broadly eradicate and control of brucellosis is important from tow aspects of health and economic. Raise up awareness of poultry- mans and educating consumers by the mass media and raise up awareness about transferable disease from milk and its products can be useful. Manuscript profile -
Open Access Article
512 - Using micellar casein concentrate (MCC) on efficiency and physicochemical properties of Iranian white brine cheese
somayeh Aghaei Ali Reza Shahab Lavasani peyman RajaeiWhite brined cheese is a very popular traditional cheese which is produced in some parts of Iran, this products is usually made from sheep,s, cow,s milk or mixture of two. Back to past several decades, one of the most challenge was increased yield of cheesemaking accord MoreWhite brined cheese is a very popular traditional cheese which is produced in some parts of Iran, this products is usually made from sheep,s, cow,s milk or mixture of two. Back to past several decades, one of the most challenge was increased yield of cheesemaking according to improved quality including chemical composition and sensory properties. So, the aims of this study were to determine physicochemical and sensory properties of white brined cheese supplemented by Micellar Casein Concentrate (MCC). Five treatments were prepared by adding 0,1,2,3 and 4% of MCC to milk used for cheesemaking and physicochemical properties (pH, acidity(dornic), dry matter%, moisture%, ash%, protein%, fat% and yield of cheesemaking) also sensory properties(flavor, color, texture and acceptability scores) were measured over 30 days of ripening period. Statistical analysis for comparison of data was Completely Randomized Design(CRD). Results showed that in parallel to dry matter%, moisture content of all treatments were decreased during 30 days of ripening period and parallel to pH, acidity of all treatments increased until end of ripening period also ash% of all treatments increased during 30 days of ripening period and the highest yield of cheesemaking , protein% and fat% were attributed to T4(containig 4% of MCC). The highest scores for flavor, color, texture and acceptability were attributed to T4(containig 4% of MCC). According to above mentioned, T1 was the best treatment among others and had high similarity to control sample with due attention to physicochemical and sensory properties. Manuscript profile -
Open Access Article
513 - Effect of different levels of somatic cell count of cow milk and lipase enzyme on free fatty acids composition and sensory properties of White brined cheese
Hamed Zarei Ali Reza Shahab Lavasani -
Open Access Article
514 - The Survey of anticancer and anti Microbial properties of Rosmarinus officinalis L, Peganum harmala L and Coffee Extracts on cell viability of Cancer cells and Pathogenic Bacteria in Foods
Ali Sharifzadeh faranak aali sayeh vahhabiDespite significant advances in radiation therapy and cancer treatments in the past 30 years, resistance to chemotherapy is a major obstacle in the recovery of patients with cancer. Resistance to chemotherapy drugs inhibits the recovery process. This study aims to evalu MoreDespite significant advances in radiation therapy and cancer treatments in the past 30 years, resistance to chemotherapy is a major obstacle in the recovery of patients with cancer. Resistance to chemotherapy drugs inhibits the recovery process. This study aims to evaluate the anticancer activity of the hydroalcolic extracts of Rosemary, Peganum and Coffee on growth inhibition of MCF-7 cell line and determine the rate of growth inhibition of pathogenic bacteria isolated from food.We examined cytotoxicity effects of three different concentrations (60,120,250 μg/ml) of Rosemary, Peganum and Coffee extracts on MCF-7and HDF cell lines. . The standard MTT assay was performed to estimate cell viability after treatment by Rosemary, Peganum and Coffee extracts. The extracts were also used with MIC on Staphylococcus aureus and E. coli bacteria isolated from food.The results of the MTT assay showed that the Rosemary, Peganum and Coffee extracts had time-and concentration-dependent anticancer activities on the MCF-7cell line compared to HDF cells statistically significant (p Manuscript profile -
Open Access Article
515 - T2MC- پلی گیاهی که از پلیمریزاسیون هموگلوبین داسی شکل درون سلولی جلوگیری کرده و بیان کانال کلسیمی فعال شده با +K را در اریتروسیت تنظیم می کند
موجیسولا کریل-اولوتای نوراح آکینولا جوسف ابدانسی< Background & Aim:Telfairia occidentalis, Moringa oleifera and Cnidoscolus aconitifolius are nutritious vegetables used individually, or in different combinations as blood boosters in managing sickle cell anemia in South-Western Nigeria. Inthis study, we evaluat More< Background & Aim:Telfairia occidentalis, Moringa oleifera and Cnidoscolus aconitifolius are nutritious vegetables used individually, or in different combinations as blood boosters in managing sickle cell anemia in South-Western Nigeria. Inthis study, we evaluated the antisickling properties of the polyherbal combination, as well as the mode(s) of action, using molecular biology techniques. < Experimental: T. occidentalis, M. oleifera and C. aconitifolius leaves were extracted separately in ethanol after identification by a taxonomist. The extracts were combined in different ratios (TMC, T2MC, TM2C, TMC2) and evaluated at 4 mg/mL concentration for antisickling properties. Ciklavit®, an antisickling nutraceutical, was utilized as the positive control. We evaluated the combination (T2MC) for the rate of inhibition of polymerization of sickle hemoglobin (HbS), erythrocyte membrane stabilization, and rehydration of dense sickle red cells in vitro. The regulation of the Gardos channel, erythropoietin (EPO), mitogenesis, and antioxidant genes was assessed in vivo by harvesting and analyzing the bone marrows, kidneys, livers of Wistar rats administered with T2MC orally at 50 and 100 mg/kg body weight for 28 days. Folic acid was employed as the positive control. < Results: The T2MC treated samples showed significantly higher (p < 0.05) antisickling activities (95.4 ± 0.15% inhibition and 95.6 ± 0.28% reversal), and cell membrane stabilization (76.8 ± 0.05%) than the positive controls. Additionally, T2MC reduced the density of sickle red cells by 18.2 ± 0.86%, and showed inhibition of polymerization of HBS comparable to positive controls. Finally, T2MC down-regulated the expression of the Gardos-channel and the erythropoietin genes suggesting that T2MC works by inhibiting the activation of Ca2+activated K+ channel, thereby preventing cell dehydration. < Recommended applications/industries: T2MC is a potent antisickling nutraceutical and could be used in the management of sickle cell disease. Manuscript profile -
Open Access Article
516 - مطالعه آزمایشگاهی بر روی فعالیت ضد داسی شدن سلولی در Terminalia arjuna و Terminalia bellirica
آناند دیلید فیرودییا آبین مانی ویجای تاوانیBackground & Aim:Combretaceae family is known for efficacy in the management of sickle cell disorder (SCD). Based on the earlier reports of anti-sickling property of Terminalia genus the study investigates in vitro antisickling properties of Terminalia MoreBackground & Aim:Combretaceae family is known for efficacy in the management of sickle cell disorder (SCD). Based on the earlier reports of anti-sickling property of Terminalia genus the study investigates in vitro antisickling properties of Terminalia arjuna and Terminalia bellirica. Experimental: Anti-sickling assay of methanolic and aqueous extract of T. arjuna and T. bellirica on sickled RBCs were evaluated at different concentrations. The osmotic fragility test was done to explore the effect of extracts on haemoglobin S solubility and sickle cell membrane stability. Additionally antioxidant activity and phytochemical analysis of extracts was evaluated. Results: Treatment with the plant extracts at different concentrations showed decrease in percentage of sickled cells. Extract of T. arjuna had a significantly higher (p < 0.05) antisickling activity at the tested concentrations of 10 mg/ml. The methanolic extract at 10 mg/ml showed the best cell membrane stability as compared to T. bellirica extract. It was observed that, T. bellirica extract was deficient of alkaloid and tannins. Moreover, all extracts/fractions showed antioxidant activity, although lesser as compared to the standard. Recommended applications/industries: It was observed that the leaf extracts of T. arjuna has a significant antisickling effect, hence it can be potentially used in clinical management of SCD. The bioactive compounds can be used to supplement as well as management drug for sickle cell disease. Manuscript profile -
Open Access Article
517 - بررسی تنوع اکوتیپی و شیمیوتیپی آویشن دنایی (Thymus daenensis Celak) در استان های اصفهان و چهارمحال و بختیاری
آبنوس کریمی عبدالله قاسمی پیربلوطی فاطمه ملک پور مهدی یوسفی احمدرضا گل پرورمقدمه و هدف: آویشن دنایی(Thymus daenensis Celak.) یکی از گیاهان دارویی متعلق به خانواده نعناع است. سرشاخه های گلدار این گیاه علفی و چند ساله کاربرد وسیعی در تهیه دارو و درمان انسان در طب سنتی دارد. مهم ترین ماده مؤثره آن، تیمول و کارواکرول می باشد. از آنجایی که شر Moreمقدمه و هدف: آویشن دنایی(Thymus daenensis Celak.) یکی از گیاهان دارویی متعلق به خانواده نعناع است. سرشاخه های گلدار این گیاه علفی و چند ساله کاربرد وسیعی در تهیه دارو و درمان انسان در طب سنتی دارد. مهم ترین ماده مؤثره آن، تیمول و کارواکرول می باشد. از آنجایی که شرایط اکولوژی نقش عمده ای در رشد، نمو، کیفیت و کمیت ماده مؤثره گیاهان دارویی دارد، تحقیق حاضر به منظور بررسی اثر عوامل اکولوژیکی بر میزان ماده مؤثره عصاره این گیاه به مرحله اجرا در آمد. روش تحقیق: در این تحقیق گیاه آویشن دنایی از 22 منطقه استان های اصفهان و چهارمحال و بختیاری جمع آوری گردید. پس از عصاره گیری و تزریق نمونه ها به دستگاه HPLC، کروماتوگرام های حاصل از دستگاه، درصد تیمول و کارواکرول هر منطقه را مشخص نمود. نتایج و بحث: بیشترین میزان تیمول (5/3%) مربوط به نمونه شیخ شبان در ارتفاع 3747 متر از سطح دریا و بیشترین میزان کارواکرول (3/2%) مربوط به نمونه لارک در ارتفاع 2370 متر از سطح دریا به دست آمد. نتایج تجزیه همبستگی نشان داد که ارتفاع از سطح دریا بر میزان تیمول اثر معنی­دار و مثبت دارد و بر میزان کارواکرول اثر معنی­داری ندارد. توصیه کاربردی- صنعتی: با توجه به اهمیت و خاصیت ضدمیکروبی ترکیبات تیمول و کارواکرول در گونه آویشن دنایی و با توجه به این که بهترین منطقه رویشگاه این گیاه با تولید بیشتر ترکیب های مذکور مربوط به منطقه شیخ شبان در استان چهارمحال و بختیاری می باشد، بنابراین استفاده از جمعیت آویشن این منطقه جهت کشت و کار و نیز ایجاد شرایط اکولوژیکی (خاک، آب و هوا، جغرافیایی) شبیه این منطقه برای تولید بیشتر این ترکیبات توصیه می شود. Manuscript profile -
Open Access Article
518 - تاثیر داروی کامپو بر القای CYP3A4 و ABCB1 در سلول های دستگاه گوارش مدل LS180
کانا هاشیموتو دایچی انوموتو شیون اوهساوا ساکی آئوکی کای تاناکا رونا یامائوچی یوکو ناکایاما کوهجی تاکاراBackground & Aim: The clinical use of some Kampo medicines has increased rapidly, and opportunities to be used concomitantly with Western medicines more frequently. Although the inhibition of cytochrome P450(CYP)-mediated drug metabolism and ABCB1-mediated transport MoreBackground & Aim: The clinical use of some Kampo medicines has increased rapidly, and opportunities to be used concomitantly with Western medicines more frequently. Although the inhibition of cytochrome P450(CYP)-mediated drug metabolism and ABCB1-mediated transport by Kampo medicine has been reported, little information is available regarding the induction of CYP enzymes or P-glycoprotein—which is encoded by the highly polymorphic ATP-binding cassette transporter B1 (ABCB1) gene—by Kampo medicine. This study aimed to evaluate the induction of CYP enzymes and ABCB1 using Kampo medicines.Experimental: Four Kampo medicines, namely Saireito, Shosaikoto, Goreisan, and Daikenchuto, were selected. The induction of CYP3A4 and ABCB1mRNA expressionwas evaluated in human-derived colon adenocarcinoma LS180 cells, which are an established model for investigating gene induction mediated by the pregnane X receptor.Results: Exposure to Saireito caused a dose-dependent increase in CYP3A4 mRNA expression. A significant increase in CYP3A4 mRNA expression was also observed with Goreisan and Daikenchuto, but not with Shosaikoto. Exposure to Saireito, Shosaikoto, and Goreisan significantly upregulated the expression of ABCB1 mRNA in a dose-dependent manner, but exposure to Daikenchuto had no such effect. These results indicate the differing induction effects of Kampo medicines and the distinct profiles of CYP3A4 and ABCB1, suggesting the upregulation of CYP3A4 or ABCB1 expression by Kampo medicines in enterocytes.Recommended applications/industries: Collectively, our results show that Kampo medicines can potentially induce the expression of CYP enzymes and ABCB1, and provide useful clinical information on the safety and efficacy of the combined use of Kampo and Western medicines. Manuscript profile -
Open Access Article
519 - بررسی اثر عصاره چند گیاه دارویی بر باکتری بروسلا آبورتوس (Brucella abortus) در شرایط In-vitro و In-vivo
عبدالله قاسمی پیربلوطی محمدرضا قاسمی حسن ممتاز احمدرضا گل پرور بهزاد حامدی سهراب شاهقلیانمقدمه و هدف: تب مالت یک بیماری عفونی باکتریایی است که عامل آن باکتریی به نام بروسلا است که می­تواند به طور مستقیم یا غیر مستقیم از دام آلوده به انسان منتقل شود. به­همین منظور مطالعه حاضر با هدف پیش­گیری و درمان این بیماری در دو شرایط آزمایشگاهی و مدل حیوانی Moreمقدمه و هدف: تب مالت یک بیماری عفونی باکتریایی است که عامل آن باکتریی به نام بروسلا است که می­تواند به طور مستقیم یا غیر مستقیم از دام آلوده به انسان منتقل شود. به­همین منظور مطالعه حاضر با هدف پیش­گیری و درمان این بیماری در دو شرایط آزمایشگاهی و مدل حیوانی انجام شد. روش تحقیق : اثرات ممانعتی برخی عصاره های گیاهان دارویی نظیر خارشتر(Alhagi camelorum Fisch.)، خوشاریزه (Echinophora platyloba DC.)، چز کوهی (Teucrium polium L.)، گل میمونی بیابانی (Scrophularia desertii Del.) و زرشک کوهی (Berberis integerrima Bunge.) بر روی رشد باکتری بروسلا آبورتوس انجام شد. نتایج و بحث: نتایج به دست آمده از روش انتشار دیسک نشان داد که بیش­ترین اثر ممانعت از رشد باکتری مربوط به عصاره آبی گیاه خارشتر با غلظت 500 میکروگرم در میلی لیتر و کمترین اثر ممانعتی مربوط به عصاره اتانولی گیاه گل میمونی بیابانی با غلظت 125 میکروگرم در میلی لیتر بود. در مقایسه دو غلظت ثابت عصاره­ها با آنتی بیوتیک مشخص شد که در غلظت 5/62 میکروگرم در میلی لیتر بیشترین اثر مربوط به آنتی بیوتیک اریترومایسین و بعد از آن استرپتومایسین و عصاره آبی خارشتر بود. در بررسی اثر متقابل دوز و نوع عصاره بر نسبت وزن اولیه به وزن ثانویه موش­های آزمایشگاهی مشخص شد که بهترین اثر مربوط به گروه دریافت کننده عصاره ترکیبی (شاهد مثبت) با دوز 400 mg/kg/day بوده و بعد از آن گروه دریافت کننده عصاره اتانولی ریشه زرشک کوهی با دوز 400 mg/kg/day بود. اثر متقابل دوز ها و عصاره های گیاهان دارویی بر نسبت وزن طحال به وزن بدن نشان داد که گروه دریافت کننده عصاره آبی خار شتر با دوز 200 mg/kg/day و بعد از آن گروه دریافت کننده داروی سنتزی اریترومایسین با دوز200 mg/kg/day بهترین نتیجه را دارا بودند. در بررسی اثر متقابل دوزها و عصاره­های گیاهان دارویی بر تیتر آنتی بادی رایت اختلاف معنی داری بین اثر متقابل دوزها و عصاره­ها بر تیتر آنتی بادی رایت نشان نداد. توصیه کاربردی/ صنعتی: با تلفیق نتایج دو روش، عصاره اندام هوایی گیاه خارشتر و ریشه زرشک کوهی به همراه آنتی بیوتیک ممکن است دارای خاصیت پیش گیری کننده بیماری تب مالت در دام باشند. Manuscript profile -
Open Access Article
520 - انتخاب مقادیر مناسب HLB برای امولسیون پایدار عسل-شی باتر و اثربخشی آن در درمان زخم سوختگی شیمیایی
جانسون ایساک عایشا دابوری کنچوکوو بن- اومه بنت ایفانی فیلیپ بیلدرزBackground & Aim: Since ancient times till today, honey and shea butter are used in wound treatment. This present study aims to determine an effective hydrophile-lipophile balance (HLB) value that will produce a stable W/O honey-shea butter emulsion and to evaluate MoreBackground & Aim: Since ancient times till today, honey and shea butter are used in wound treatment. This present study aims to determine an effective hydrophile-lipophile balance (HLB) value that will produce a stable W/O honey-shea butter emulsion and to evaluate its healing potential on chemical burn wound in mice.Experimental: Using various ratios of span 20/tween 20, 6 formulations of honey-shea butter emulsion were prepared and subjected to accelerated stability study as per ICH guideline. The most stable preparation was further evaluated for its wound healing ability. The animals were sacrificed via chloroform inhalation after treatment for 7 days from wound created by dropping 0.2 ml, hydrochloric acid for 15 sec. The burn area was harvested and subjected to histopathological study.Results: Most stable emulsion was those prepare with ratio 5:5 of span 20/ tween 20. Haematoxylin-eosin and Verhoeff-Van Gieson stain revealed that groups treated with this emulsion had normal fibroblast, fibrocyte, epidermal cells, inflammatory cells, gland cells, collagen and elastic fibres; outperforming honey, shea butter and silver sulfadiazine groups. The present formulation gave a percent wound contraction of 36, while those of honey, shea butter, silver sulfadiazine were 29, 25 and 28, respectively. The occlusive effect of emulsion and the synergistic effect achieved by combining honey and shea butter could also be responsible for its superior wound healing activity.Recommended applications/industries: Our study concluded that honey-shea butter prepared with 5:5 span 20/tween 20 was relatively stable and possesses greater wound healing activity compared to commercial preparation and can safely be utilize as an effective natural therapy for burn wound. Manuscript profile -
Open Access Article
521 - اثر عصاره ریشه Suregada zanzibariensis (Baill) بر سطح قند خون، پروفایل لیپیدی و بافت شناسی پانکراس در موش های صحرایی دیابتی ناشی از استرپتوزوتوسین-نیکوتینامید
ژاپت جوزفات سیپریان امپیندا راس ماسوBackground & Aim: Ethnobotanical studies have shown that Suregada zanzibariensis roots are used by traditional healers and the community for the treatment of diabetes mellitus. Therefore, this study was undertaken to investigate the effect of the ethyl acetate extra MoreBackground & Aim: Ethnobotanical studies have shown that Suregada zanzibariensis roots are used by traditional healers and the community for the treatment of diabetes mellitus. Therefore, this study was undertaken to investigate the effect of the ethyl acetate extract of Suregada zanzibariensis roots (EAESZ) on blood sugar levels, lipid profile, and pancreatic histology in streptozotocin-nicotinamide-induced diabetic rats.Experimental: Rats were induced to have diabetes by interstitial injection of streptozotocin nicotinamide, followed by daily oral administration of the ethyl acetate extract of Suregada zanzibariensis roots (EAESZ) for 28 days at doses of 350, 500, and 700 mg/kg body weight. The effect of EAESZ on serum lipid profiles and pancreatic β-cells in diabetic rats were examined after 28 days of administration of the extract. While fasting, blood glucose levels were measured every seven days.Results: The administration of EAESZ at doses of 350, 500, and 750 mg/kg significantly decreased the fasting blood glucose levels compared to the diabetic control rats. Also, total cholesterol (TC), low-density lipoprotein (LDL), and triglyceride (TG) levels decreased while high-density lipoprotein (HDL) levels increased in all treated groups compared to diabetic control rats. Furthermore, there was no significant difference (P>0.05) in body weight of treated diabetic rats compared to standard control diabetic rats, while there was a significant difference (P<0.05) with diabetic control rats.Recommended applications/industries: These results indicate that EAESZ has high antidiabetic potential along with significant hypoglycemic and hypolipidemic effects. However, more studies are needed to identify and isolate compounds responsible for those properties. Manuscript profile -
Open Access Article
522 - بررسی اثر ضدباکتریایی و فیتوشیمیایی عصاره متانولی و استونی گونههای Cupressus sempervirens و Juniperus excelsa بر برخی بیماریهای مهم غذایی
سیما یزدانی منیر دودی زهرا رضایتمند لادن رحیم زاده ترابیBackground & Aim: The unfettered usage of antibiotics has engendered a mounting resistance of bacteria to these agents, thereby necessitating the discovery and development of novel compounds and medications to a greater extent than previously. The focal point of thi MoreBackground & Aim: The unfettered usage of antibiotics has engendered a mounting resistance of bacteria to these agents, thereby necessitating the discovery and development of novel compounds and medications to a greater extent than previously. The focal point of this research was to explore the chemical constituents of acetone and methanol-extracted samples of Cupressus sempervirens and Juniperus excelsa, as well as their potential inhibitory actions against a prevalent food-borne pathogen.Experimental: This experimental investigation was conducted on standard strains of Staphylococcus aureus (PTCC 1430), Bacillus cereus (PTCC 1431), Listeria monocytogenes (PTCC 1298), Escherichia coli (PTCC 1399), and Shigella dysentery (PTCC 1188). Following the preparation of methanol and acetone extracts derived from Juniperus excelsa and Cupressus sempervirens using Clevenger apparatus, the antimicrobial efficacy was assessed by both qualitative agar well diffusion method and quantitative macrodilution method. The active constituents present in the methanol and acetone extracts of the plants were identified by gas chromatography-mass spectrometry (GC/MS) analytical method. Means were compared with Duncan's test at the 5% probability level.Results: The findings of this investigation pertaining to the antimicrobial potency of the extracts, ascertained via the qualitative agar well diffusion method, indicated its efficacy against Gram-positive strains including S. aureus and B. cereus. The methanol extracts of the J. Excelsa were found to produce smaller inhibition zones on the tested bacteria compared to other plant extracts. The highest sensitivity to the acetone extract of C. sempervirens and J. excelsa observed in S. aureus and B. cereus. The extracts obtained from the two plant did not demonstrate any discernible impact on the Gram-negative bacteria that are commonly associated with foodborne pathogens. The findings obtained through gas chromatography-mass spectrometry (GC/MS) indicated the presence of efficacious components such as Benzene 1,2,4,5-tetramethyl, and Cyclopropane cyclopenta in J. excels extract. The acetone extract of J. excelsa showed more potent antimicrobial constituents than its methanolic counterpart. It is anticipated that in forthcoming times, the acetone extract derived from this botanical specimen may be employed to prevent bacterial-induced foodborne illnesses.Recommended applications/industries: Duo to the existence of a range of bioactive compounds in the acetone extracts obtained from C. sempervirens and J. excels, these extracts have the potential to be used against the development of foodborne infections and diseases caused by bacterial agents. Manuscript profile -
Open Access Article
523 - اثر سمیت سلولی عصاره هیدروالکلی آویشن دنایی بر روی رده سلول های سرطانی MCF-7
فاطمه صادقی سامانی حسین سازگار عبداله قاسمی پیربلوطیمقدمه و هدف: سرطان پستان دومین سرطان شایع در زنان بعد از سرطان ریه می­باشد. با توجه به اینکه ترکیبات گیاهی قرن­هاست که برای درمان سرطان استفاده می­شوند. هدف از این مطالعه بررسی اثر سمیت سلولی عصاره هیدروالکلی آویشن دنایی بر روی رده سلول­های سرطانی MCF- Moreمقدمه و هدف: سرطان پستان دومین سرطان شایع در زنان بعد از سرطان ریه می­باشد. با توجه به اینکه ترکیبات گیاهی قرن­هاست که برای درمان سرطان استفاده می­شوند. هدف از این مطالعه بررسی اثر سمیت سلولی عصاره هیدروالکلی آویشن دنایی بر روی رده سلول­های سرطانی MCF-7 بود. روش تحقیق: سلول­های سرطانی MCF-7 و سلول­های طبیعی فیبروبلاست در محیط کشت DMEM حاوی سرم جنین گاو و آنتی­بیوتیک کشت گردیدند. این سلول­ها در مجاورت دوزهای مختلف عصاره هیدروالکلی آویشن دنایی (156/0، 312/0، 625/0، 25/1، 5/2 میلی­گرم بر میلی­لیتر) قرار گرفتند و به مدت 24، 48 و 72 ساعت انکوبه شدند. پس از پایان انکوباسیون، از روش تغییر یافته آزمون رنگ سنجی MTT جهت تعیین سمیت سلولی عصاره­ استفاده شد. نتایج و بحث: نتایج حاصل از تست MTT نشان داد که عصاره­ هیدروالکلی آویشن دنایی اثر ضد سرطانی وابسته به دوز و زمان بر سلول­های سرطانی MCF-7 دارد، به طوری که با افزایش غلظت عصاره و انکوباسیون 72 ساعت بیشترین درصد مرگ سلولی مشاهده شد ( 05/0 > P). عصاره گیاه سمیت سلولی قابل توجهی را بر روی سلول­های طبیعی فیبروبلاست نشان نداد.لذا به نظر می­رسد با تحقیقات بیشتر در آینده، می­توان از ترکیبات آن در درمان سرطان بهره جست. توصیه­ ی کاربردی/ صنعتی:با توجه به اینکه مصرف داروهای گیاهی برای درمان بسیاری از بیماری­ها در حال افزایش است، عصاره هیدروالکلی آویشن دنایی به دلیل داشتن خاصیت آنتی­اکسیدانی می­تواند در درمان سرطان در کنار دارو درمانی استفاده شود. Manuscript profile -
Open Access Article
524 - اثر باز دارنده رشد عصاره شبدر قرمز بر سلولهای سرطانی راجی در لنفوم بورکیت
مرتضی داودی شهریار سعیدیان رضا صغیری زهرا زمانی غلام رضا بخشی خانیکیBackground & Aim: In folk medicine, red clover (Trifolium pratense) use to treat some diseases such as whooping cough, asthma, eczema, and some ophthalmic dysfunction. Due to its phytoestrogens and antioxidant-rich compounds, it is recommended to alleviate some canc MoreBackground & Aim: In folk medicine, red clover (Trifolium pratense) use to treat some diseases such as whooping cough, asthma, eczema, and some ophthalmic dysfunction. Due to its phytoestrogens and antioxidant-rich compounds, it is recommended to alleviate some cancers. This paper was conducted to study the anti-cancer and apoptosis effects of red clover extract (RCE) on the Raji cell line in Burkitt's lymphoma.Experimental: Red clover lyophilized powder (CAS = 85085-25-2) with a fixed ratio of Formononetin, Biochanin A, Daidzein, and Genistein was acquired from Sigma Aldrich German company. Raji cells were obtained from the Pasteur Institute of Iran-Tehran. Raji cells were treated with different concentrations of RCE, and viable cells were measured at an interval of 24, 48, and 72 hours incubation in three days by MTT assay. Agarose gel electrophoresis was used to determine the DNA degradation. Annexin V-FITC/PI kit and flow cytometry assay were used to determine the percent of apoptotic and necrotic treated Raji cells. Also, expression changes in cMYC, ID3, and P53 genes were measured by real-time PCR. Results: Red clover extract can prevent in vitro proliferation of the Raji cells in a time and dose-dependent manner. RCE, as well as c-MYC gene suppression and induction of ID3 and P53 genes, enters the Raji cells in the apoptosis stages with an acceptable percentage and has complication cure potential in Burkitt's lymphoma. Recommended applications/industries: The extract used in this study combines four components. The individual evaluation effects of Formononetin, Biochanin A, Daidzein, and Genistein on Raji cells are recommended. Manuscript profile -
Open Access Article
525 - تاثیرات عصاره هیدروالکلی گل ختمی (Althaea officinalis L) بر برخی پارامترهای بیوشیمیایی و خونی ماهی کپور معمولی (Cyprinus carpio
فهیمه فلاح پور مهدی بنایی نرگس جوادزادهمقدمه و هدف: گیاه ختمی (Althae officinalis L.) یکی از معروف­ترین گیاهان دارویی است که به دلیل داشتن خواص ضد باکتریایی و آنتی­اکسیدانی در طب سنتی مورد استفاده قرار می­گیرد. هدف از انجام این مطالعه، بررسی تاثیر تجویز عصاره گل ختمی بر پارامترهای خونی و بیوشیمیا Moreمقدمه و هدف: گیاه ختمی (Althae officinalis L.) یکی از معروف­ترین گیاهان دارویی است که به دلیل داشتن خواص ضد باکتریایی و آنتی­اکسیدانی در طب سنتی مورد استفاده قرار می­گیرد. هدف از انجام این مطالعه، بررسی تاثیر تجویز عصاره گل ختمی بر پارامترهای خونی و بیوشیمیایی در ماهی کپور است. روش تحقیق:در این آزمایش 150 عدد ماهی کپور معمولی (با میانگین وزنی 40/4±65/37 ) با جیره­های حاوی 0/0 (کنترل)، 5/2، 5 و 10 گرم عصاره گل ختمی به مدت 60 روز تغذیه شدند. سپس در روزهای 30 و 60 آزمایش، شاخص­های خون­شناسی و بیوشیمیایی ماهی­ها اندازه­گیری شد. نتایج و بحث: هیچ گونه تغییر معنی­داری در تعداد سلول قرمز خون، هموگلوبین، هماتوکریت و میانگین حجم گویچه­ها، تعداد نوتروفیل­ها، بازوفیل­ها و ائوزینوفیل­ها در ماهیانی که با غلظت­های مختلف عصاره گل ختمی به مدت 60 روز تغذیه شدند، مشاهده نگردید. تجویز عصاره ختمی (5 گرم) موجب افزایش معنی­داری در تعداد سلول­های سفید خون و لنفوسیت­ها در روز 60 شد. از سویی دیگر تجویز 5 و 10 گرم عصاره ختمی سبب کاهش معنی­دار منوسیت­ها گردید. تجویز عصاره ختمی در طی 60 روز تاثیر معنی­داری بر فعالیت آنزیم­های آلانین آمینوترانسفراز، آلکالین فسفاتاز و کراتین­فسفوکیناز و نیز سطح کراتینین خون نداشت. فعالیت آنزیم آسپارتات آیمنوترانسفراز و لاکتات دهیدروژناز پلاسما و همچنین سطح پروتئین کل پلاسما و آلبومین به طور معنی­داری در ماهیان تحت تیمار غلظت 10 گرم عصاره ختمی در بالاترین سطح قرار داشت. سح کلسترول و تری­گلیسرید نیز در گروه­های تحت تیمار غلظت­های 5 و 10 گرم عصاره ختمی به طور معنی­داری کاهش یافت. تغییرات معنی­داری مشاهده شده در فاکتورهای خونی و بیوشیمیایی ماهیان تحت تیمار غلظت 10 گرم عصاره ختمی ممکن است به سمیت سلولی نسبت داد؛ در حالی که تجویز 5/2 و 5 گرم عصاره ختمی تاثیر سوئی بر شاخص­های خونی و بیوشیمیایی ماهیان کپور در این مطالعه نداشت. توصیه کاربردی/ صنعتی:براساس این نتایج، تجویز پیش­بالینی غلظت­های مشخصی از عصاره گل ختمی (5/2 و 5 گرم) برای ماهیان کپور معمولی مفید بوده است. Manuscript profile -
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526 - کاربرد الیسیتورها برای افزایش تولید متابولیت های ثانویه در سوسپانسیونهای کشت سلول و اندام گیاهی
مریم محمدی فارسانی عبدالله قاسمی پیربلوطیدر زیست فناوری همواره به بررسی مسیرهای جایگزین برای تولید ترکیبات طبیعی توجه میشود. سیستمهای کشت سلول و اندام گیاهی برای تولید متابولیت های ثانویه ای که اهمیت تجاری در صنایع غذایی و دارویی دارند قابل جایگزینی میباشند. با این حال، تقریباً تعداد کمی از محیطهای کشت این Moreدر زیست فناوری همواره به بررسی مسیرهای جایگزین برای تولید ترکیبات طبیعی توجه میشود. سیستمهای کشت سلول و اندام گیاهی برای تولید متابولیت های ثانویه ای که اهمیت تجاری در صنایع غذایی و دارویی دارند قابل جایگزینی میباشند. با این حال، تقریباً تعداد کمی از محیطهای کشت این ترکیبات را سنتز میکنند و میزان این سنتز و مدت زمانی که صرف میکند قابل مقایسه با استفاده از یک گیاه کامل میباشد. روشهایی شامل تغییر محیط کشت (افزودن مواد مغذی و هورمونی) و شرایط محیطی (تغییرات دما، pH و اسمزی) و همین طور از مواد استخراجی و ترکیبی نیز در این راهبردها استفاده می شده است. امروزه از دستکاری ژنتیکی مسیرهای بیوسنتتیک با استفاده از مهندسی متابولیکی که امروزه برای بهبود تولیدات متابولیت های مورد نیاز تکنیکی قدرتمند شده است استفاده میشود. نتایج مطالعات انجام شده نشان میدهد که هم الیسیتورهای زیستی و هم غیر زیستی سنتز متابولیتهای ثانویه را در محیط کشت سلولهای گیاهی افزایش میدهند. Manuscript profile -
Open Access Article
527 - مقایسه ترکیبات پلی فنلی، خاصیت مهارکنندگی رادیکالهای آزاد و تاثیر بر آدیپوژنز در Chorisia Chodatii و Chorisia Speciosa
جون رفعت ثمر یهیا دسوکی محمد احمد رامادان محمد صالح کامل جونکیو هان هیرکو ایسودامقدمه و هدف: Chorisia گیاهی مهم از خانواده Bombacaceae است که به طور سنتی برای انواع بیماریها استفاده می شود. با توجه به غنی بودن آن از نظر برخی از ترکیبات فیتوشیمیایی زیست فعال، برخی از گونه های Chorisia طیف گسترده ای از اثرات مهم بیولوژیکی را نشان داده اند. بر این اسا Moreمقدمه و هدف: Chorisia گیاهی مهم از خانواده Bombacaceae است که به طور سنتی برای انواع بیماریها استفاده می شود. با توجه به غنی بودن آن از نظر برخی از ترکیبات فیتوشیمیایی زیست فعال، برخی از گونه های Chorisia طیف گسترده ای از اثرات مهم بیولوژیکی را نشان داده اند. بر این اساس، در مطالعه حاضر، به مقایسه پتانسیل آنتی اکسیدانی و اثرات آن بر آدیپوژنز در دو گونهChorisia chodatii و Chorisia speciosa بر اساس مقدار ترکیبات فنولی موجود در آنها پرداخته شده است. روش تحقیق: کل ترکیبات فنلی و پتانسیل مهار رادیکالهای آزاد در عصاره الکلی برگ، گل، میوه و دانه در دو گونه ذکر شده، و فراکشنهای اصلی در عصاره برگ و گل، به ترتیب با استفاده از روش فولین سیوکالتیو و DPPH مورد بررسی قرار گرفتند. به علاوه تاثیر آنها بر آدیپوژنز در مدل سیستمهای آدیپوسیتهای 3T3-L1 مورد ارزیابی قرار گرفت و بررسی ترکیبات مختلف فیتوشیمیایی آن نیز در نظر گرفته شد. نتایج و بحث: کل عصاره اتانولی همراه با فراکشن های به دست آمده از قسمتهای مختلف در هر دو گونه، باعث القای تمایز وابسته به غلظت در آدیپوسیتهای 3T3-L1 شد ولی در کمترین غلظت (µg/ml 10-5) باعث کاهش قابل توجه در اندازه ذرات چربی شد. به علاوه این عصاره ها تاثیرات قوی بر مهار رادیکالهای آزاد از خود نشان دادند. فراکشن های به دست آمده از بخشهای مختلف گیاه با استفاده از اتیل استات، آب و کلروفرم به ترتیب بیشترین تاثیر بر آدیپوژنز، مهار رادیکالهای آزاد و بیشترین مقدار ترکیبات فنلی را نشان دادند. توصیه های کاربردی/ صنعتی: نتایج به دست آمده در مجموع نشان داد که تاثیر هر دو گونه Chorisia بر آدیپوژنز و رادیکالهای آزاد ناشی از میزان قابل توجه فلاونوئیدها و ترکیبات فنلی در آنها است. به علاوه نتایج حاکی از ارزش بالقوه این دو گونه در پیشگیری از اختلالات مرتبط با چاقی و بیماریهای مرتبط با رادیکال های آزاد است. مطالعات بیشتر برای بررسی اساس مولکولی تاثیر آنها بر آدیپوژنز همراه با آنالیزهای فیتوشیمیایی دقیق به خصوص در عصاره های غنی از فلاونوئیدها و ترکیبات قطبی پیشنهاد می شود. Manuscript profile -
Open Access Article
528 - شناسایی ترکیبات شیمیایی و فعالیت ضد باکتری اسانس دو گونه آویشن
امین هادی پناه مجتبی خرمیمقدمه و هدف :استافیلوکوکوس اورئوس (Staphylococcus aureus) ازجمله باکتریهای بیماریزا و از عوامل مهم عفونتهای بیمارستانی درجوامع انسانی می باشد. این باکتری نسبت به داروهای شیمیایی به سرعت درحال مقاوم شدن می باشد و در بسیاری از کشورها تلاش زیادی جهت یافتن ترکیبهای جدید به Moreمقدمه و هدف :استافیلوکوکوس اورئوس (Staphylococcus aureus) ازجمله باکتریهای بیماریزا و از عوامل مهم عفونتهای بیمارستانی درجوامع انسانی می باشد. این باکتری نسبت به داروهای شیمیایی به سرعت درحال مقاوم شدن می باشد و در بسیاری از کشورها تلاش زیادی جهت یافتن ترکیبهای جدید به عنوان جایگزین مناسب این آنتی بیوتیکها انجام می شود. هدف از این تحقیق شناسایی ترکیبات شیمیایی و فعالیت ضد باکتری اسانس 2 گونه آویشن (Thymus vulgaris L.) و (Thymus daenensis Celak)کشت شده در شرایط آب و هوایی استان فارس بود. روش تحقیق: قسمتهای هوایی آویشن باغی و آویشن دنایی در مرحله آغاز گلدهی در منطقه استهبان (استان فارس) در جنوب ایران، در سال 1393 جمع آوری شد. استخراج اسانس به روش تقطیر با آب و به کمک دستگاه اسانس گیری طرح کلونجر صورت گرفت و میزان اسانس به وسیله دستگاه کروماتوگرافی گازی متصل به طیف سنج جرمی (GC/MS) مورد تجزیه و شناسایی قرار گرفت. اسانس استافیلوکوکوساورئوس با سطوح مختلف آنتی بیوتیک وانکومایسین، متیسیلین و اکساسیلین مورد بررسی قرار گرفت. نتایج و بحث:نتایج بدست آمده از این تحقیق نشان داد که به ترتیب 28 و26 ترکیب در اسانس آویشن باغی و آویشن دنایی شناسایی شدند. ترکیبات اصلی اسانس آویشن باغی شامل تیمول (14/63%)، پارا-سیمین (45/9%)، گاما-ترپینن (67/8%) و کارواکرول (14/3%) حاصل شد. ترکیبات اصلی اسانس آویشن دنایی شامل تیمول (2/71%)، گاما-ترپینن (81/8%)، پارا-سیمین (8/3%) و کارواکرول (4/2%) بدست آمد. نتایج حاکی ازآن بود که MIC و MBC اسانس آویشن باغی و آویشن دنایی به ترتیب تاثیر بازدارندگی رشد 1/0 تا 5/0 میکرولیتردر یک میلی لیتر بر باکتری استافیلوکوکوس اورئوس دارند. توصیه کاربردی/صنعتی: اسانس آویشن دنایی به طور محسوسی ویژگی ضدباکتری بارزتری نسبت به اسانس آویشن باغی از خود نشان داد. Manuscript profile -
Open Access Article
529 - تاثیر باکتریهای افزایش دهنده رشد گیاه بر عصاره و فاکتورهای فیزیولوژیکی آویشن دنایی (Thymus daenensis Celak) در شرایط تنش خشکی
علی عبداللهی محمد فیضیان غزاله مهدی پوریانزمینه و هدف: در حال حاضر استفاده از میکروارگانیسم های مفید به عنوان نهاده های کشاورزی پایدار و کارآمد با امیدواری در کاهش اثرات منفی خشکسالی مورد توجه قرار گرفته است. به منظور بررسی تأثیر ریزوباکتری های تقویت کننده رشد گیاه (PGPR) و تنش خشکی بر اسانس (EO) و فاکتورهای فی Moreزمینه و هدف: در حال حاضر استفاده از میکروارگانیسم های مفید به عنوان نهاده های کشاورزی پایدار و کارآمد با امیدواری در کاهش اثرات منفی خشکسالی مورد توجه قرار گرفته است. به منظور بررسی تأثیر ریزوباکتری های تقویت کننده رشد گیاه (PGPR) و تنش خشکی بر اسانس (EO) و فاکتورهای فیزیولوژیکی آویشن دنایی (Thymus daenensis Celak)، یک آزمایش در سال 2017 در شهرکرد انجام شد.شرح آزمایش: آزمایش به صورت فاکتوریل در قالب طرح کاملا تصادفی با سه تکرار انجام شد. فاکتورها چهار رژیم آبیاری و دو تلقیح PGPR بودند. فاکتور اول شامل چهار رژیم آبیاری عبارت بودند از: آبیاری کامل (A: عدم استرس) ، آبیاری پس از کاهش 20-25٪ ظرفیت مزرعه (FC) (L: استرس کم) ، آبیاری پس از کاهش 35-40 FC (M: استرس خفیف) و آبیاری پس از کاهش 60-55٪ FC (S: استرس شدید). فاکتور دوم شامل دو تیمار PGPR ، عدم تلقیح (C: شاهد) و تلقیح با PGPR (M: Pseudomonas fluorescens سویه 187 و Pseudomonas aeruginosa سویه MPFM) بود.یافته ها: نتایج نشان داد که تنش خشکی باعث کاهش وزن خشک ریشه و شاخساره ، محتوای نسبی آب ، رنگدانه های فتوسنتزی و پارامترهای تبادل گازی شد اما تلقیح PGPR باعث بهبود آنها گردید. با افزایش تنش خشکی ، پرولین ، مالون دی آلدئید ، نشت الکترولیت و مقاومت روزنه ای افزایش یافت، اما تلقیح PGPR باعث کاهشاین فاکتورها در تیمارهای مربوطه شد. تلقیح PGPR باعث افزایش تولید اسانس گردید اگرچه این افزایش از نظر آماری معنی دار نبود اما تنش آب تولید اسانس را کاهش داد.توصیه های صنعتی و عملی: نتایج نشان می دهد که تلقیح PGPR می تواند یک استراتژی عالی برای کاهش اثرات منفی تنش خشکی در کشت آویشن دنایی در شرایط تنش خشکی باشد، بنابراین کشاورزان مناطق نیمه خشک می توانند با استفاده از PGPR در تنش کم آب بیشترین مقدار EO در در آویشن دنایی تولید کنند. Manuscript profile -
Open Access Article
530 - اثر زمان های مختلف برداشت بر خصوصیات کمی (مورفولوژیک) و کیفی آویشن دنایی (Thymus daenensis Celak) در منطقه اصفهان
احمدرضا گل پرور عبدالله قاسمی پیربلوطی حسین زینلی امین هادی پناهمقدمه و هدف: آویشن دنایی (Thymus daenensis Celak.) متعلق به خانواده نعناعیان (Lamiaceae) می باشد. این گیاه به عنوان ضد نفخ، هضم کننده غذا، ضداسپاسم، ضد سرفه و خلط آور و به علت داشتن ترکیب اصلی تیمول و کارواکرول در صنایع دارویی، بهداشتی و آرایشی کاربرد فراوانی دارد.  Moreمقدمه و هدف: آویشن دنایی (Thymus daenensis Celak.) متعلق به خانواده نعناعیان (Lamiaceae) می باشد. این گیاه به عنوان ضد نفخ، هضم کننده غذا، ضداسپاسم، ضد سرفه و خلط آور و به علت داشتن ترکیب اصلی تیمول و کارواکرول در صنایع دارویی، بهداشتی و آرایشی کاربرد فراوانی دارد. روش تحقیق: به منظور بررسی اثر زمان برداشت بر صفات مورد نظر آویشن دنایی ‎آزمایشی در قالب طرح بلوک­های کامل تصادفی با سه تکرار در مزرعه تحقیقاتی دانشگاه آزاد اسلامی واحد ‏خوارسگان (اصفهان) در سال های 1388 و 1389 انجام شد. تیمارهای مورد بررسی، دوره های فنولوژیکی (زمان­های ‏برداشت) شامل دوره رویشی، ظهور آغازههای گل، ظهور 50 درصد گل آذینها، گلدهی کامل و ‏زمان تشکیل بذر بود.‏نتایج و بحث: نتایج تجزیه واریانس نشان داد که تأثیر مراحل مختلف برداشت روی صفات ارتفاع بوته، قطر بوته، تعداد شاخه، ارتفاع بلندترین ساقه، وزن تر و خشک بیوماس و میزان تیمول در سطح یک درصد و برای سایر صفات تفاوت­ها معنی دار نبود. نتایج به دست آمده از مقایسه میانگین نشان داد که بیشترین ارتفاع بوته (83/31 سانتی متر) از مرحله بذردهی حاصل شد. بیشترین قطر بوته (50/38 سانتی­متر) از مرحله بذردهی به دست آمد که تفاوت معنی داری با اکثر مراحل، داشت. از طرفی، بیشترین وزن تر بیوماس (10621 کیلوگرم در هکتار) و بیشترین وزن خشک بیوماس (4243 کیلوگرم در هکتار) از مرحله بذردهی و کمترین وزن تر بیوماس (5545 کیلوگرم در هکتار) و کمترین وزن خشک بیوماس (2035 کیلوگرم در هکتار) از مرحله رویشی حاصل شد. بیشترین درصد اسانس (1.41 %) از مرحله 50% گلدهی و بیشترین میزان تیمول (84.1%) از مرحله رویشی حاصل شد.توصیه کاربردی/صنعتی: به طورکلی با توجه به نتایج این تحقیق، می توان مرحله بذردهی را به عنوان مناسب ترین زمان برداشت به منظور حصول حداکثر عملکرد وزن تر و خشک بیوماس آویشن دنایی معرفی نمود اما برای دستیابی به بیشترین میزان تیمول مرحله رویشی را معرفی نمود. Manuscript profile -
Open Access Article
531 - Celebrity diplomacy and Attractiveness and simplification of international politics in public perception
Arash Beidollahkhani Yaser KahrazehCelebrity diplomacy is a key tool in attracting public attention to the public issues and crisis in international politics. Over the past two decades, celebrities have increasingly used their power and fame to draw global attention to important international issues such MoreCelebrity diplomacy is a key tool in attracting public attention to the public issues and crisis in international politics. Over the past two decades, celebrities have increasingly used their power and fame to draw global attention to important international issues such as poverty, debt crisis, infectious diseases, war, etc and based on these activities, they have been recognized as celebrity diplomats. This has led to a widespread use of celebrities in international politics. Diplomatic activity of celebrities broadens the informal political milieus of international politics and it is transferred important issues of international politics to the center of every day life's discourse of ordinary people. Moreover, it is given the Aesthetic dimension to the international politics. Accordingly, the fundamental question of the present research is that how does celebrity diplomacy effect on international politics? In the answer to this question and with a descriptive-analytical method this paper emphasizes that diplomatic activity of celebrities in international politics increases the focus and attraction of public opinion and ordinary citizens on international issues and political crises. The attention that was not possible through state-level and traditional diplomacy. Manuscript profile -
Open Access Article
532 - Synthesis and characterization of Pt3Co bimetallic nanoparticles supported on MWCNT as an electrocatalyst for methanol oxidation
Mohammad Hossein Nobahari Ahmad Nozad Golikand Mojtaba Bagherzadeh -
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533 - None-platinum electrode catalysts and membranes for highly efficient and inexpensive H2 production in microbial electrolysis cells (MECs): A review
Abudukeremu Kadier Washington Logroño Pankaj Kumar Rai Mohd Sahaid Kalil Azah Mohamed Hassimi Abu Hasan Aidil Abdul Hamid -
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534 - Ecofriendly synthesis of biscoumarin derivatives catalyzed by EDTA-modified magnetic animal bone meal nanoparticles in water
Ahmad Reza Momeni Sadegh Bakhtiar -
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535 - Nano-BF3/cellulose as a biodegradable novel catalyst for synthesis of highly functionalized tetrahydropyridines
Seyede Azita Fazeli-Attar Bi Bi Fatemeh Mirjalili -
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536 - Photocatalytic self-cleaning properties of lanthanum and silver co-doped TiO2 nanocomposite on polymeric fibers
Hadi Fallah Moafi -
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537 - Diethylenetriamine supported on cellulose as a biodegradable and recyclable basic heterogeneous catalyst for the synthesis of spirooxindole derivatives
Batol Zakerinasab Mohammad Ali Nasseri Ali Allahresani -
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538 - Modification of silica with 2,4-dinitrophenylhydrazanomethylphenol for monosaccharide productions
Kasim Mohammed Hello Hayder Mihsen Mosa -
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539 - Cellulose sulfuric acid catalyzed multicomponent reaction for efficient synthesis of pyrimido and pyrazolo[4,5-b]quinolines under solvent-free conditions
Seyyedeh Cobra Azimi -
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540 - Synthesis and photocatalytic activity of nanosized modified mesocellulous silica foams (MCFs) with PW12 and vanadium oxide
Leili Shabani Hamid Aliyan -
Open Access Article
541 - Novel and cost-effective biocatalyst consisting of nanofibrillated cellulose and TiCl3 for the synthesis of 2,3'-dihydroquinazolin-4-(1H)-ones
Hannaneh Heidari Kobra Nikoofar Yeganeh Shahedi -
Open Access Article
542 - A Nickel Sublayer: An Improvement in the Electrochemical Performance of Platinum-Based Electrocatalysts as Anodes in Glucose Alkaline Fuel Cells
Behnam Moeini Masoumeh Ghalkhani Tahereh G. Avval Matthew R. Linford Rasol Abdullah Mirzaie -
Open Access Article
543 - Nano-cellulose-OSnCl4-x: Green and natural-based renewable nanocatalyst for one-pot synthesis of 2-amino-3-phenylsulfonyl-4H-pyran derivatives
Sayed Rasul Shafe-Mehrabadi Bahareh Sadeghi Mohammad Hossein Mosslemin Saeedeh Hashemian -
Open Access Article
544 - Mini-Review on Graphene Quantum Dots as an electro-catalyst in fuel cell
Bita Roshanravan Habibollah Younesi -
Open Access Article
545 - A green procedure for synthesis of xanthene derivatives: Micellar solution of sodium dodecylphosphonate catalyzes condensation reaction of aldehydes and β-naphthol in aqueous media
Razieh Ghashghaei Soheila Ghassamipour -
Open Access Article
546 - Cellulose sulfuric acid: an efficient biopolymer-based catalyst for the synthesis of 5H-dibenzo[b,i]xanthene-tetraones and spiro[dibenzo[b,i]xanthene-13,3'-indoline]-pentaones under solvent free conditions
Seyyedeh Cobra Azimi Hassan Kefayati -
Open Access Article
547 - Synthesis and in-vitro antimicrobial screening of 3-cinnamoyl coumarin and 3-[3-(1H-indol-2-yl)-3-aryl-propanoyl]-2H-chromen-2-ones
Somnath Gholap Umesh Deshmukh Macchindra Tambe -
Open Access Article
548 - An Ant-Colony Optimization Clustering Model for Cellular Automata Routing in Wireless Sensor Networks
عارف صفری -
Open Access Article
549 - جواب تقریبی مدلی از عفونت HIVCD4+T از مرتبه کسری غیر خطی با استفاده از روش تابع پایه شعاعی ربع دیفرانسیلی
کوکب چلمبری حمیده ابراهیمی زینب آیاتیIn this research, differential quadrature radial basis functions Method is performed to a fractional order model of HIV infection of CD4+T. Here, Caputo fractional derivative is used and it is approximated by forward finite difference method. Results have been compared MoreIn this research, differential quadrature radial basis functions Method is performed to a fractional order model of HIV infection of CD4+T. Here, Caputo fractional derivative is used and it is approximated by forward finite difference method. Results have been compared with the results of Laplace Adomian decomposition method (LADM), Laplace Adomian decomposition method-pade (LADM-pade), Runge-Kutta, Variational iteration method (VIM) and Variational iteration method-pade (VIM-Pade) for α_1=α_2=α_3 and residual functions have been plotted. And also approximate solutions of suggested method for different order of fractional derivatives have been shown. Manuscript profile -
Open Access Article
550 - پیادهسازی DEA فازی درون مدل PEM جهت ارزیابی عملکرد سازمانهای پروژهمحور: یک مطالعۀ موردی
اویس ترابی محمّدمیلاد احمدی روحالله تولاییسازمان های پروژه محور در صنایع بالادستی سهم زیادی از منابع ملی را در اختیار دارند و نقش مهمی در توسعه یک کشور ایفا می کنند. ارزیابی عملکرد سازمان های پروژه محور می تواند به مدیران کمک کند تا از ورودی ها به طور موثر استفاده کنند و راه خود را برای دستیابی به اهداف هموار ک Moreسازمان های پروژه محور در صنایع بالادستی سهم زیادی از منابع ملی را در اختیار دارند و نقش مهمی در توسعه یک کشور ایفا می کنند. ارزیابی عملکرد سازمان های پروژه محور می تواند به مدیران کمک کند تا از ورودی ها به طور موثر استفاده کنند و راه خود را برای دستیابی به اهداف هموار کنند. برای ارزیابی عملکرد سازمان های پروژه محور، شاخص های کمی و کیفی زیادی وجود دارد. محاسبه کارایی از طریق تحلیل پوششی داده ها (DEA) یک شاخص رایج برای ارزیابی عملکرد در چنین شرکت هایی است. در مدل سنتی DEA دادههای واضح مورد نیاز است در حالی که در دنیای واقعی، بیشتر دادهها نادقیق و نامطمئن هستند. یکی از دلایل اصلی عدم قطعیت مربوط به اطلاعات غیر کمی، ناقص و دست نیافتنی است که باعث ادغام منطق فازی و مجموعه های فازی در مدل های مختلف مانند DEA می شود.ایدۀ اصلی پژوهش حاضر ترکیب رویکردهای کمی و کیفی در ارزیابی عملکرد برای بهرهگیری از هر دو و دستیابی به نتایج دقیقتر است. از این رو، در این مقاله، یک مدل ترکیبی مبتنی بر تحلیل پوششی داده های فازی (FDEA) و مدل تعالی پروژه (PEM) برای ارزیابی عملکرد در سازمان های پروژه محور پیشنهاد شده است. ابتدا ارزیابی عملکرد توسط مدل PEM داده های فازی انجام می شود. سپس پیاده سازی فازی DEA در مدل PEM انجام می شود که در آن ورودی ها و خروجی های مدل FDEA معیارهای مدل PEM هستند. مدل هیبریدی پیشنهادی برای ارزیابی 30 شرکت پتروشیمی در ایران استفاده شده است. مقایسه نتایج هر دو مدل نشاندهنده ضریب همبستگی تقریباً 90/0 در سطح معنیداری 01/0 است که نشاندهنده همبستگی مناسب بین دو مدل است. Manuscript profile -
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551 - On the Picard-Mann approach for hybridizing the double direction method for solving a system of nonlinear equations.
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552 - THE APPLICATION OF DATA ENVELOPMENT ANALYSIS METHODOLOGY TO IMPROVE THE BENCHMARKING PROCESS IN THE EFQM BUSINESS MODEL (CASE STUDY: AUTOMOTIVE INDUSTRY OF IRAN)
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555 - استنباط بیزی مولفههای واریانس–کواریانس و پارامترهای ژنتیکی برای صفات اقتصادی هلشتاینهای ایران از طریق نمونهگیری گیبس
H. Faraji-Arough A.A. Aslaminejad M. Tahmoorespur M. Rokouei M.M. Shariatiهدف از این مطالعه، برآورد پارامترهای ژنتیکی صفات تولید، تولید مثل و بهداشت گاوهای هلشتاین ایران با استفاده از روش بیزی از طریق نمونه­گیری گیبس بود. رکوردهای اولین شیردهی 320666 گاو هلشتاین متولد شده از 7696 نر و 260302 ماده که مابین سالهای 1370 تا 1389 توسط مرکز اص Moreهدف از این مطالعه، برآورد پارامترهای ژنتیکی صفات تولید، تولید مثل و بهداشت گاوهای هلشتاین ایران با استفاده از روش بیزی از طریق نمونه­گیری گیبس بود. رکوردهای اولین شیردهی 320666 گاو هلشتاین متولد شده از 7696 نر و 260302 ماده که مابین سالهای 1370 تا 1389 توسط مرکز اصلاح نژاد دام کشور جمع­آوری شده بود، مورد استفاده قرار گرفت. مولفه­های واریانس- کواریانس با استفاده از مدل حیوانی چند صفتی از طریق نمونهگیری گیبس برآورد شدند. بعد از رسیدن به همگرایی، دامنه تراکم پسین وراثت­پذیری برای شیر (MY305)، چربی (FY305)، پروتئین (PY305)، سن در اولین گوساله ­زایی (AFC)، فاصله گوساله ­زایی (CI) و نمره سلولهای بدنی (SCS) به ترتیب 275/0-255/0، 215/0-195/0، 225/0-195/0، 275/0-260/0، 080/0-065/0 و 075/0-055/0 بود. دامنه همبستگی ژنتیکی بین 121/0- (بین تولید چربی و سن در اولین گوساله زایی) تا 914/0 (بین تولید شیر و پروتئین) و همبستگی فنوتیپبی بین 083/0- (بین تولید شیر و نمره سلولهای بدنی) تا 929/0 (بین تولید شیر و پروتئین) به دست آمد. نتایج این مطالعه نشان داد که صفات تولیدی و سن در اولین گوساله زایی تنوع ژنتیکی کافی برای بهبود در برنامه­های اصلاحی را دارند. همبستگی­های ژنتیکی برآورد شده پیشنهاد کننده این هستند که صفات تولید شیر و فاصله گوساله ­زایی در صورتی که افزایش تولید شیر در اهداف انتخابی مد نظر قرار گیرد می­توانند تحت تأثیر قرار بگیرند. همبستگی ژنتیکی بالا بین فاصله گوساله­ زایی و نمره سلولهای بدنی بیان کننده این است که افزایش فاصله گوساله ­زایی منجر به افزایش نمره سلولهای بدنی می­شود. Manuscript profile -
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556 - Genotyping of Lactoferrin and CXCR1 Genes in Guilan Native Cows and Its Association with Milk Somatic Cell Score
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560 - آثار مکمل جیرهای اسیدهای ارگانیک القاءکننده ایمنی محافظتی بر علیه کوکسیدیوز
آ.ی. عبدوالهی ایکس.جی. یو ی.کیو. فو م.و. وانگ ن.اس. کی م.اچ. گیزا اس. کالون و.د. پان ایکس.ل. شی ی. فانگ اس. ویو و. هو ل.پی. تان کا.ایکس. لی ز. وانگ جی.جی. زو د.ی. فنگ جی.کیو. لیاین مطالعه آثار سه محصول از اسیدهای ارگانیک جیرهای (Acidomix® AFG؛ Activate® AD و Lacplus) روی ایمنی محافظتی بر علیه کوکسیدیوزها را ارزیابی کرد. 280 جوجه 1 روزه گوشتی به طور تصادفی درون 8 گروه شامل 5 تکرار (7 پرنده به ازای هر تکرار)، شامل 2 کنترل (منفی=N؛ مثبت Moreاین مطالعه آثار سه محصول از اسیدهای ارگانیک جیرهای (Acidomix® AFG؛ Activate® AD و Lacplus) روی ایمنی محافظتی بر علیه کوکسیدیوزها را ارزیابی کرد. 280 جوجه 1 روزه گوشتی به طور تصادفی درون 8 گروه شامل 5 تکرار (7 پرنده به ازای هر تکرار)، شامل 2 کنترل (منفی=N؛ مثبت=P) و 6 گروه مکمل اسید ارگانیک (1 درصد AFG، 1 درصد DA، 1 درصد Lacplus، 2 درصد AFG، 2 درصد DA و 2 درصد Lacplus) تقسیم شدند. به استثنای کنترل N (آلوده نشده) ، تمامی 7 گروه به طور خوراکی با 105 × 8 از اووسیتهای هاگآور شده Eimeria tenella در روز 12 بعد از هچ به چالش کشیده شدند. نمونههای خون، طحال و روده کور در روز 22 و 35 بعد از هچ جمعآوری شدند. رشد وزنی بدن، خارج شدن اووسیت مدفوعی، درجه تخریب، نرخ مرگ و میر و pH سکوم بررسی شدند. تست ELISA برای تشخیص خوشه مولکولهای سلول T افتراقی (CD4+ و CD8+) استفاده شده و واکنش زنجیرهای پلیمراز رونوشتبردار معکوس (RT-PCR) برای تشخیص کموکاینهای پیش التهابی (INFγ) و بیان سایتوکاینها (IL-8، IL-15 و IL-17) بکار گرفته شدند. نتیجه نشان داد که مکملسازی اسیدهای ارگانیک به طور معنیداری رشد وزنی بدن را افزایش، ضریب تبدیل خوراک را بهبود، و درجات جراحات و شاخص اووسیت (0.05>P) در مقایسه با گروه کنترل P (آلوده شده غیر مکمل) را کاهش داد. نرخ مرگ و میر در گروه کنترل P بالاتر بود. pH روده کور معنیدار بود (0.05>P) و حداکثر در گروه کنترل P مشاهده شد. جوجههای تغذیه شده با 2 درصد DA و 1 درصد Lacplus درصد بالاتری از مولکولهای سلول T CD4 داشتند، اما مولکولهای سلول T CD8 کمتری داشتند، که ارائه کننده یک عملکرد محافظتی از این زیرمجموعههای سلول T در پاسخ ایمنی ذاتی در مقابل عفونت E. tenella است. کموکاینهای روده کور و طحال و بیان mRNA سایتوکاینها شامل INFγ، IL-8، IL-15 و IL-17 سطوح بالاتری از رونویسی در مقایسه با کنترلهای N و P نشان دادند، که نشان میدهد محصولات اسید ارگانیک ممکن است با بهبود تولید آنها آثار محافظتی خود را اعمال کرده باشند. نتیجه گرفته شده که Activate® DA در سطوح 2 درصد و Laxplus در سطوح 1 درصد هم در روز 22 و هم در روز 35 بعد از هچ بهترین آثار ضدکوکسیدیال را نشان دادهاند. Manuscript profile -
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561 - شرایط منجر به استرس اکسیداتیو در گاوهای شیری
ج. گونزالز-مالدونادو ر. رانگل-سانتوس ر. رودریگز-دلارا گ. رامیرز-والوردهرادیکالهای آزاد به طور طبیعی توسط ارگانیسمهای زنده تولید میشوند، در نرخ تولید کنترل شده آنها عملکردهای فیزیولوژیکی را به عنوان مولکولهای انتقال پیام ایفا میکنند. با این وجود، شرایط منجر به تولید بیش از حد که ظرفیت ضد اکسیداتیو را از بین میبرند استرس اکسیداتیو را Moreرادیکالهای آزاد به طور طبیعی توسط ارگانیسمهای زنده تولید میشوند، در نرخ تولید کنترل شده آنها عملکردهای فیزیولوژیکی را به عنوان مولکولهای انتقال پیام ایفا میکنند. با این وجود، شرایط منجر به تولید بیش از حد که ظرفیت ضد اکسیداتیو را از بین میبرند استرس اکسیداتیو را به وجود میآورند. در نتیجه، صدمه به غشاء سلولی، پروتئین، DNA و مرگ سلول مشاهده میشود. گاوهای شیری به استرس اکسیداتیو حساس هستند. شرایطهایی مانند عفونتها، اختلالات متابولیکی و استرس گرمایی در گاوها با خالیکردن غلظتهای آنتیاکسیدانهای بدنی یا با افزایش تولید رادیکالهای آزاد درونزاد به عنوان ایجادکننده استرس اکسیداتیو شناخته شدهاند. پاسخ ارگانیسم به استرس اکسیداتیو توسط فعال­سازی عوامل سلولی که بعد از ارزیابی صدمه به سلول، یک سیگنال بازیابی یا مرگ برنامهریزی خواهد شد. هدف از این بررسی تقویت دانش مرتبط با استرس اکسیداتیو در خواننده و فراهم آوردن اطلاعات در مورد شرایط منجر به این نوع از استرس و پاسخ سلولی به آن در گاوهای شیری است. Manuscript profile -
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562 - اثر باکتوسل و تویوسرین بهعنوان پروبیوتیک، بر عملکرد رشد، فراسنجههای خونی و مورفومتری روده جوجههای بوقلمون
م. چمنیآزمایشی برای بررسی اثر استفاده از پروبیوتیک­های باکتوسل (پدیوکوکوس اسیدی­لاکتیکی) و تویوسرین (باسیلوس سرئوس) بر عملکرد، لاشه، فراسنجه­های خونی و مورفولوژی روده­ جوجه­های بوقلمون انجام شد. تعداد 240 قطعه جوجه­ بوقلمون نر یکروزه­ نژاد نیکولاس د Moreآزمایشی برای بررسی اثر استفاده از پروبیوتیک­های باکتوسل (پدیوکوکوس اسیدی­لاکتیکی) و تویوسرین (باسیلوس سرئوس) بر عملکرد، لاشه، فراسنجه­های خونی و مورفولوژی روده­ جوجه­های بوقلمون انجام شد. تعداد 240 قطعه جوجه­ بوقلمون نر یکروزه­ نژاد نیکولاس در سه تیمار جیره­ای با چهار تکرار در هر تیمار، مورد استفاده قرار گرفتند. جیره­ پایه بر اساس ذرت-سویا بود. تیمارها عبارت بودند از: 1- گروه کنترل (جیره­ پایه)، 2- جیره­ پایه + باکتوسل (109cfu پدیوکوکوس اسیدی­لاکتیکی به ازای هر گرم جیره) و 3- جیره­ی پایه + باکتوسل (109cfu باسیلوس سرئوس به ازای هر گرم جیره). جوجه بوقلمون­ها در شرایط نرمال از روز اول تا 84 در پن­های جداگانه و روی بستر در شرایط محیطی کنترل شده پرورش یافتند. خوراک و آب به ­طور آزاد در اختیار جوجه­ها قرار داشت. وزن­کشی هفتگی برای تعیین میانگین وزن جوجه­های هر پن انجام شد. مصرف خوراک نیز به ­طور هفتگی اندازه­گیری و ضریب تبدیل خوراک برای کل دوره محاسبه شد. در روز 84 پرورش، 8 جوجه از هر تیمار برای اندازه­گیری فراسنجه­های خونی کلسترول، تری­گلیسیرید، هتروفیل، لنفوسیت و نیز بررسی ویژگی­های مورفولوژیکی روده­ کوچک به­ طور تصادفی انتخاب و کشتار شدند. نتایج این مطالعه نشان داد که استفاده از این دو پروبیوتیک تأثیر معنی­داری بر وزن بدن، مصرف خوراک، ضریب تبدیل خوراک، کلسترول، تری­گلیسرید، HDL و LDL نداشت (05/0P>). نتایج معنی­داری در کاهش ضخامت اپی­تلیوم، افزایش طول پُرزها، و افزایش تعداد سلول­های گابلت روده­ کوچک مشاهده شد (05/0P<). همچنین پرندگانی که از این دو پروبیوتیک استفاده کرده بودند، در محتویات ایلئومی خود دارای تعداد کلی­فرم­های کمتری نسبت به گروه کنترل بودند (05/0P<). بنابراین، با توجه به نتایج این پژوهش می­توان نتیجه گرفت که استفاده از این پروبیوتیک­ها در دوز توصیه شده (109cfu به ازای هر کیلوگرم خوراک) فاقد اثر معنی­دار بر فراسنجه­های خونی و عملکرد جوجه بوقلمون­ها است. نکته­ کلیدی در استفاده از این پروبیوتیک­ها، اثر آنها در حفظ سلامتی دستگاه گوارش و مقاومت به پاتوژن­ها و نیز پیشگیری از اختلالات گوارشی است. Manuscript profile -
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563 - Effects of Thyme Essential Oil and Disodium Fumarate on Ruminal Fermentation Characteristics, Microbial Population and Nutrient Flow in a Dual Flow Continuous Culture System
ه. براز ح. جهانی-عزیزآبادی ع. عزیزی -
Open Access Article
564 - اعتبارسنجی ژنهای خانهدار جهت نرمال کردن Real Time PCR در سلولهای سوماتیکی تلیسهای شیری هلشتاین
م. محقق-دولتآبادی ح. حسینی-دولتآبادی ا. حیدری ارجلو ر. محمودیتکنیک Real time PCR مطمئنترین روش ارزیابی سطوح بیان mRNA میباشد. اگرچه، جهت به دست آوردن نتایج دقیق، انتخاب ژنهای مرجع مناسب جهت نرمال کردن دادههایReal time PCR ضروری است. هدف از این تحقیق بررسی پایداری بیان 3 ژن پتانسیل مرجع (ACTB، GAPDH و UXT) در سلولهای سوم Moreتکنیک Real time PCR مطمئنترین روش ارزیابی سطوح بیان mRNA میباشد. اگرچه، جهت به دست آوردن نتایج دقیق، انتخاب ژنهای مرجع مناسب جهت نرمال کردن دادههایReal time PCR ضروری است. هدف از این تحقیق بررسی پایداری بیان 3 ژن پتانسیل مرجع (ACTB، GAPDH و UXT) در سلولهای سوماتیکی شیر تلیسههای شیری هلشتاین در شرایط متفاوت بود. برای این منظور، دو نوع نمونه شیر از 18 تلیسه شیری سالم در مراحل مختلف شیردهی و 4 تلیسه مبتلا به ورم پستان در این آزمایش در نظر گرفته شد. RNA کل از سلولهای سوماتیکی استخراج شد و سپس cDNA سنتز شد. واکنش Real time PCR برای ژنهای ACTB، GAPDHو UXT به عنوان ژنهای خانهدار کاندیدا انجام شد و نتایج توسط برنامه BestKeepe مورد تجزیه و تحلیل قرار گرفت. ارزیابی ژنهای توسط Real time PCR نشان داد که همه ژن ها در تلیسه های شیری سالم و مبتلا به ورم پستان بیان شده بودند. علاوه بر این، ژنهای UXT و GAPDH به ترتیب دارای کمترین و بیشترین مقدار بیان بودند. ژن ACTB به عنوان مناسبترین کنترل داخلی در نظر گرفته شد و در سلولهای سوماتیکی صرف نظر از شرایط تلیسههای شیری دارای ثبات بیان بود. بر این اساس، نتایج مطالعه ما میتواند در انتخاب ژن مرجع مناسب برای نرمال کردن سطوح بیان در سلولهای سوماتیکی شیر تلیسههای شیری کمک کند. Manuscript profile -
Open Access Article
565 - تولید شکمبهای متان، جمعیت میکروبی و خصوصیات تخمیر شکمبهای در گوسفند تحت تأثیر عصاره برگ پنیرک قرار میگیرد: مطالعه برونتنی
ص. خاموشی ف. کفیلزاده ح. جهانی-عزیزآبادی و. ناصریهدف از این مطالعه بررسی اثر عصاره برگ گیاه پنیرک (به میزان صفر، 25، 50 و 100 میکرولیتر\30 میلی لیتر محیط کشت) بر رشد باکتریهای سلولایتیک و کل باکتریهای زنده، جمعیت پروتوزواها، تولید متان، پتانسیل تجزیه الیاف نامحلول در شوینده خنثی، و بازده تخمیر شکمبه ای علوفه یولاف در Moreهدف از این مطالعه بررسی اثر عصاره برگ گیاه پنیرک (به میزان صفر، 25، 50 و 100 میکرولیتر\30 میلی لیتر محیط کشت) بر رشد باکتریهای سلولایتیک و کل باکتریهای زنده، جمعیت پروتوزواها، تولید متان، پتانسیل تجزیه الیاف نامحلول در شوینده خنثی، و بازده تخمیر شکمبه ای علوفه یولاف در شکمبه گوسفند در شرایط برون تنی بود. افزودن عصاره پنیرک به میزان 25، 50 و 100 میکرولیتر، سبب افزایش خطی(01/0>P) قابلیت هضم حقیقی ماده خشک، الیاف نامحلول در شوینده خنثی و فاکتور تفکیک علوفه یولاف و کاهش (01/0>P) تولید متان بعد از 24 ساعت انکوباسیون در شرایط برونتنی، شد. نسبت به تیمار شاهد، افزودن عصاره برگ پنیرک در مقادیر 25 و 50 میکرولیتر سبب کاهش(01/0>P) پتانسیل تولید گاز و در مقادیر 25، 50 و 100 میکرولیتر سبب افزایش (01/0>P) فاز تأخیر (به ترتیب 95/0، 01/1 و 13/1 نسبت به 61/0 ساعت)، ثابت نرخ تولید گاز (b) و ثابت نرخ تولید گاز در زمان تولید 50 درصد از کل گاز تولیدی (c)، شد. افزایش این عصاره تعداد کل پروتوزواها و گونههای انتودنیومها، ایزوتریشاها، دیپلودنیوم و گونه اوفیروس کولکس را کاهش داد (01/0>P). تعداد کل باکتریها و باکتریهای سلولولایتیک تحت تأثیر افزودن عصاره برگ پنیرک قرار نگرفت. نتایج این مطالعه نشان داد که عصاره برگ پنیرک دارای پتانسیل بهبود تخمیر شکمبهای میباشد. Manuscript profile -
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566 - بررسی پروتئین تک یاختهای به عنوان یک خوراک نامتعارف در تغذیه جوجههای گوشتی
م.ر. پورعلمی س. سیفی ع.ر. عبدالهی کاکرودی ر. خوشبختپروتئین تک یاختهای تعریفی برای سلولهای خشک شدهای است که از ارگانیسمهای تک سلولی تشکیل شدهاند و به عنوان منبع پروتئینی در غذاهای انسان یا خوراک حیوانات مورد استفاده قرار میگیرند. آزمایشی برای ارزیابی اثرات سطوح مختلف پروتئین تک یاختهای بر روی میکروفلور مدفوع و صفا Moreپروتئین تک یاختهای تعریفی برای سلولهای خشک شدهای است که از ارگانیسمهای تک سلولی تشکیل شدهاند و به عنوان منبع پروتئینی در غذاهای انسان یا خوراک حیوانات مورد استفاده قرار میگیرند. آزمایشی برای ارزیابی اثرات سطوح مختلف پروتئین تک یاختهای بر روی میکروفلور مدفوع و صفات تولیدی جوجههای گوشتی انجام شد. در مجموع 192 جوجه یکروزه نر نژاد راس 308، به صورت تصادفی به 4 تیمار تقسیم شدند. هر تیمار شامل 48 پرنده و 4 تکرار 12 قطعهای بود. از روز اول پرورش، جوجهها با یک جیره غذایی بر پایه ذرت و سویا به همراه سطوح مختلف پروتئین تک یاختهای (0، 5، 10 و 15 درصد جیره) تغذیه شدند. در روز 47 دوره پرورش، چهار پرنده از هر تیمار به صورت تصادفی برای کشتار و مطالعه میکروبی انتخاب شدند. تعداد کل باکتریهای هوازی، لاکتوباسیلها و کولی فرمهای روده در تیمارهای مختلف، تفاوت معنیداری نداشت. پروتئین تک یاختهای در سطوح 10 و 15 درصد باعث تلفات بالا شد. همچنین استفاده از پروتئین تک یاختهای، تأثیرات نامطلوبی بر وزنگیری، مصرف غذا و بازده خوراک داشت. در نتیجه، اگر چه استفاده از پروتئین تک یاختهای باعث کاهش قیمت جیره شد، اما تأثیرات نامطلوبی بر عملکرد پرندگان داشت. Manuscript profile -
Open Access Article
567 - Comparative Effect of Different Milking Methods and Udder Hygiene on Somatic Cell Count and Milk Quality in Dairy Cows
Z. Rehman Khalil S. Akhter A. Rahman I. Ahmad S. Khan S.M. Sohail I. Amin Khalil F. Ullah -
Open Access Article
568 - Cryopreservation of Spermatogonial Stem Cells of Native Goat of Iran
M. Mohebbi G. Moghaddam B. Qasemi-Panahi H. Daghigh Kia S.A. Rafat G. Hamidian -
Open Access Article
569 - سلول سوختی میکروبی: روش جدید برای تعیین ارزش غذایی پنبه دانه کامل مورد استفاده در تغذیه نشخوارکنندگان
م. بشارتی ا. تقی زادههدف از این مطالعه، تعیین همبستگی بین تکنیک تولید گاز آزمایشگاهی و سلول­های سوختی میکروبی و معرفی روش جدید برای ارزیابی خوراک مورد استفاده در جیره­های نشخوارکنندگان است. تیمارهای مورد آزمایش: 1) جیره کنترل (بدون پنبه دانه، مننسین و ویتامین E، (CD)؛ 2) جیره حاوی 2 Moreهدف از این مطالعه، تعیین همبستگی بین تکنیک تولید گاز آزمایشگاهی و سلول­های سوختی میکروبی و معرفی روش جدید برای ارزیابی خوراک مورد استفاده در جیره­های نشخوارکنندگان است. تیمارهای مورد آزمایش: 1) جیره کنترل (بدون پنبه دانه، مننسین و ویتامین E، (CD)؛ 2) جیره حاوی 20 درصد پنبه دانه کامل (CSD)؛ 3) تیمار حاوی 20 درصد پنبه دانه کامل به همراه 12000 واحد ویتامین E به ازای هر گاو در روز (CSDE) و 4) تیمار حاوی 20 درصد دانه پنبه کامل به همراه 24 ppm مننسین در کیلوگرم DMI برای هر گاو در روز (CSDM). برای آزمایش سلول­های سوختی میکروبی، پیکربندی خانگی MFC شامل دو سیلندر از نوعPlexiglass بود. نتایج بدست آمده نشان داد که تیمار حاوی ویتامین E تولید گاز بیشتری نسبت به سایر تیمارها داشت. تولید گاز در تیمار حاوی موننسین کمتر از سایر تیمارها بود. تیمار با ویتامین E دارای مقادیر ولتاژ، جریان و قدرت بیشتری در مقایسه با سایر تیمارها بود. داده­های به دست آمده نشان داد که اضافه کردن موننسین در مقایسه با تیمار CSD باعث بهبود عملکرد سلول­های میکروبی گردید. نتایج نشان داد که بین مقادیر تولید گاز و عملکرد سلول­های سوختی میکروبی همبستگی بالایی وجود دارد. Manuscript profile -
Open Access Article
570 - Association of Somatic Cell Score with Production Traits in Iranian Holstein Cows
Z. Ghasemi A.A. Aslaminejad M. Tahmoorespur M. Rokouei H. Faraji Arough -
Open Access Article
571 - Genetic Trends for Milk Yield, Persistency of Milk Yield,Somatic Cell Count and Calving Interval in Holstein Dairy Cows of Iran
A. Chegini A.A. Shadparvar N. Ghavi Hossein-Zadeh -
Open Access Article
572 - The Effects of Sugar Beet Pulp with Tallow and Soybean Oil on Broiler Chicken Performance and Jejunum Morphology
F. Aziz-Aliabadi A. Hassanabadi A. Golian S. Zerehdaran H. Noruzi -
Open Access Article
573 - امکانسنجی تشخیص اولیه بیماری ورم پستان در دامهای شیری با استفاده از پردازش نقشه های گرمایی
م.ر. گلزاریان ح. سلطانعلی ا. دوستی ایرانی س.ه. ابراهیمیبیماری ورم پستان دام به ­عنوان یکی از شایع­ترین بیماری­ها در واحدهای پرورش گاو شیری مطرح می­باشد که از یکسو سلامتی دام­ها را تحت شعاع قرار داده و از سوی دیگر منجر به کاهش پویایی تولید محصولات لبنی شده است. از این ­رو هدف از این مطالعه بررسی تشخیص Moreبیماری ورم پستان دام به ­عنوان یکی از شایع­ترین بیماری­ها در واحدهای پرورش گاو شیری مطرح می­باشد که از یکسو سلامتی دام­ها را تحت شعاع قرار داده و از سوی دیگر منجر به کاهش پویایی تولید محصولات لبنی شده است. از این ­رو هدف از این مطالعه بررسی تشخیص بیماری ورم پستان در گاوهای شیری با نژاد هلشتاین با استفاده از پردازش تصاویر گرمایی بود. به­ منظور قابلیت تفکیکپذیری دام­ها و مقایسه بهتر نتایج حاصل از نقشه­های گرمایی، فاکتورهای چون میزان شیردهی، تعداد سلول­های سوماتیک و نیز تست ورم پستان کالیفرنیایی به عنوان مرجع آزمایش در نظر گرفته شدند. نتایج حاصل از روش همبستگی اسپیرمن نشان داد که یک رابطه معکوسی (97/0R=) بین سلول­های سوماتیک و مقادیر شیر ثبت شده وجود دارد. نتایج قابلیت تشخیص بیماری با کمک پردازش نقشه­های گرمایی حاکی از آن بود که میانگین اختلافات دمایی بین بافت سالم و غیرسالم در پستان دام­ها برابر 44/0 درجه سانتی­گراد بوده است. به ­عبارتی دقت تشخیص این روش برابر 3/57 درصد به دست آمد. به منظور نتایج بهتر حاصل از روش پردازش تصاویر گرمایی، مدیریت پارامترهایی چون کنترل اثرات منفی تابش نور، عدم وجود مو و کرک در ناحیه پستان دام، کنترل دما در ناحیه اتصال پستان با پای دام و مدیریت زایدات پوست، در مطالعات آتی پیشنهاد گردید. Manuscript profile -
Open Access Article
574 - موقعیتیابی گرلین در بیضه گاو
آ. بایزیدی آذر ب. شکرالهیگرلین، پپتید 28 اسید آمینه آسیله شده، به عنوان لیگاند اندوژنوسی برای گیرنده ترشحی هورمون رشد (GH) و نقش آن در تولید­ مثل که اخیراً منتشر شده شناسایی شده است. عقیده بر این است که محل بیان گرلین در بیضهها ممکن است نقش آن را در تنظیم موضعی نشان دهد. در این مطالعه موق Moreگرلین، پپتید 28 اسید آمینه آسیله شده، به عنوان لیگاند اندوژنوسی برای گیرنده ترشحی هورمون رشد (GH) و نقش آن در تولید­ مثل که اخیراً منتشر شده شناسایی شده است. عقیده بر این است که محل بیان گرلین در بیضهها ممکن است نقش آن را در تنظیم موضعی نشان دهد. در این مطالعه موقعیتیابی ایمنوهیستوشیمی (IHC) گرلین در بافت بیضه گاو هلشتاین با استفاده از آنتیبادی مونوکلونال ضد گرلین به عنوان آنتی‎بادی اولیه و آنتی‎بادی پلیکلونال دانکی ضد IgG خرگوشی گونژوگه شده با هورس رادیش پراکسیداز (HRP) به عنوان آنتیبادی ثانویه انجام گرفت. نمونههای بیضه از سه گاو هلشتاین 2-5/1 ساله جمعآوری شدند و جهت قرار گرفتن در پارافین در مرحله بعدی در فرمالین 10 درصد نگهداری شدند. مقاطع بافتی با ضخامت 5 میکرون برای آزمایش IHC تهیه شد. واکنشهای ایمنی برای سلول‎های اسپرماتوژنیک و سلول‎های لایدیگ و سرتولی ارزیابی شدند. عقیده بر این است که محل بیان گرلین در مراحل اسپرماتوژنز، سلولهای لایدیگ و سرتولی ممکن است نقش آن را در تنظیم موضعی نشان دهد. این یکی از اولین تحقیقاتی است که شواهد مولکولی را برای وجود گرلین در سلول‎های بافت بیضه گاو هلشتاین فراهم میکند. Manuscript profile -
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575 - Supplemental Glutathione Improves Post-Thaw Quality of Holstein Bulls Sperm in a Nanomicelle based Extender
T. Nadri A. Towhidi S. Zeinoaldini G. Riazi M. Zhandi M. Sharafi -
Open Access Article
576 - پیشبینی اپی توپهای سلولهایB و Tآنتیژن Omp25 از باکتری بروسلا ملی تنسیس به منظور طراحی واکسن نوترکیب گوسفندی
س. یوسفی م. طهمورثپور م.ه. سخاوتیبروسلوز یکی از رایج ترین بیماریهای دامی است که توسط باکتری گرم منفی بروسلا ایجاد می­شود. با توجه به ضرر­های جدی اقتصادی و درمانی این بیماری که برای دام و انسان همواره به ارمغان دارد تلاش­های بسیاری جهت جلوگیری و درمان این بیماری توسط واکسن­های نوترکیب ب Moreبروسلوز یکی از رایج ترین بیماریهای دامی است که توسط باکتری گرم منفی بروسلا ایجاد می­شود. با توجه به ضرر­های جدی اقتصادی و درمانی این بیماری که برای دام و انسان همواره به ارمغان دارد تلاش­های بسیاری جهت جلوگیری و درمان این بیماری توسط واکسن­های نوترکیب بر پایه آنتیژن­های غشای پروتئینی خارجی صورت می­گیرد. بدین منظور هدف از مطالعه حاضر بررسی خصوصیات بیوانفورماتیکی آنتی ژن Omp25 به عنوان یکی از آنتیژنهای غالب غشای پروتئینی باکتری بروسلا بوده است. در این پژوهش از نرم افزار­های بیوانفورماتیکی مختلفی برای پیشبینی اپی توپ­های B وT، ساختار دوم و سوم پروتئین، خصوصیات ایمنیزایی و ویژگی­های هضم پروتئین استفاده گردید. پیش از استفاده از نرم افزارها میزان دقت آنها توسط دادههای تجربی اعتبار سنجی گردید. نتایج آنالیز بیوانفورماتیکی نشان داد که پنج اپی توپ برای سلولهای B در موقعیتهای 44-26، 79-59، 112-88، 166-146، 202-175 و پنج اپی توپ برای سلولهای T در مکانهای 10-1، 22-14، 132-122، 162-154 و 213-206 وجود دارد. تمامی اپی توپهای شناسایی شده به جز اپی توپهای 10-1 و 22-14 دارای توانایی ایمنیزایی بودند. نهایتاً اپی توپ ناحیه 162-154 به عنوان یک اپی توپ مشترک بین سلولهای B و T جهت طراحی واکسن نوترکیب پیشبینی گردید. Manuscript profile -
Open Access Article
577 - Comparative Expression Analysis of Spermatogonial Stem Cell Markers in Cattle and Sheep
F. Nasri Ahangar M. Zandi M.R. Sanjabi A. Ghaedrahmati -
Open Access Article
578 - برآورد پارامترهای ژنتیکی و روند ژنتیکی نمره سلولهای بدنی گاوهای هلشتاین ایران با استفاده از رکوردهای روز آزمون
K. Kheirabadi S. Alijaniهدف از این پژوهش برآورد پارامترهای ژنتیکی و روند ژنتیکی نمره سلولهای بدنی (SCS) سه دوره شیردهی نخست گاوهای هلشتاین ایران با استفاده از مدل رگرسیون تصادفی و روش حداکثر درست نمایی محدود شده بود. اطلاعات مورد استفاده شامل 340318 رکورد روز آزمون مربوط به 41526 حیوان در 288 Moreهدف از این پژوهش برآورد پارامترهای ژنتیکی و روند ژنتیکی نمره سلولهای بدنی (SCS) سه دوره شیردهی نخست گاوهای هلشتاین ایران با استفاده از مدل رگرسیون تصادفی و روش حداکثر درست نمایی محدود شده بود. اطلاعات مورد استفاده شامل 340318 رکورد روز آزمون مربوط به 41526 حیوان در 288 گله، 89969 رکورد روز آزمون مربوط به 11750 حیوان در 127 گله، و 20010 رکورد روز آزمون مربوط به 2461 حیوان در 60 گله، به ترتیب برای دورههای شیردهی اول، دوم و سوم بین سالهای 2002 تا 2010 بود. اثرات ثابت شامل سال زایش، سن-فصل در هنگام زایش (به صورت رگرسیون ثابت برای هر کلاس از این اثر) و گله-تاریخ رکورد برداری بود. برآورد واریانسهای ژنتیک افزایشی، تنها با تغییرات جزئی، برای همه دورههای شیردهی روند مشابهی را نشان داد. برآوردهای وراثت پذیری برای دوره شیردهی اول (03/0 تا 07/0) کمتر از این مقدار برای دورههای شیردهی دوم (07/0 تا 11/0) و سوم (08/0 تا 17/0) بود. همبستگی-های ژنتیکی بین رکوردهای روز آزمون نمره سلولهای بدنی برای روزهای مجاور بالا و بین دو انتهای دوره شیردهی پائین، و با افزایش دوره شیردهی کاهش یافت. همبستگیهای ژنتیکی بین دورههای شیردهی بالاتر از 70/0، اما برای همبستگیهای محیطی در دامنه 22/0 تا 51/0 بود. همبستگیهای ژنتیکی بین دورههای شیردهی تائید میکند که ژنهای کنترل کننده نمره سلولهای بدنی برای دورههای شیردهی مختلف مشابه بوده و انتخاب حیوان برای نمره سلولهای بدنی دوره شیردهی اول روی نمره سلولهای بدنی دیگر دورههای شیردهی تأثیرگذار خواهد بود. روند ژنتیکی نمره سلولهای بدنی تا سال 1995 مطلوب و بعد از آن نامطلوب بود. سطح نسبتاً بالای نمره سلولهای بدنی و روندهای ژنتیکی مثبت آن (431/0 تا 701/0 سال/میلیلیتر/سلول) نشان میدهند که در ایران بهبود ژنتیکی نمره سلولهای بدنی در سطح قابل قبولی انجام نشده است. Manuscript profile -
Open Access Article
579 - اثر شمارش یاختههای پیکری کُل و افتراقی، مرحله شیردهی و تعداد دورههای شیردهی بر لیپولیز و ترکیب فیزیکوشیمیایی شیر شتر (Camelus dromedaries) و گاو
اچ. حامد آ.ف. ال فکری آ. گرگوریمطالعه حاضر با هدف بررسی اثرات شمارش یاخته­های پیکری (SCC)، SCC افتراقی (ماکروفاژ (MAC)، لیمفوسیت (LYM) و لوکوسیت­های چندهسته­ای (PMN))، تعداد و مرحله شیردهی بر ترکیب شیر در شیر شتر و گاو صورت گرفته است. شیر شتر به طور معنی­داری (05/0>P) حاوی مواد معد Moreمطالعه حاضر با هدف بررسی اثرات شمارش یاخته­های پیکری (SCC)، SCC افتراقی (ماکروفاژ (MAC)، لیمفوسیت (LYM) و لوکوسیت­های چندهسته­ای (PMN))، تعداد و مرحله شیردهی بر ترکیب شیر در شیر شتر و گاو صورت گرفته است. شیر شتر به طور معنی­داری (05/0>P) حاوی مواد معدنی بیشتری است. سطح لیپولیز در شیر شتر مشابه شیر گاو است. سطح لیپولیز همگام با افزایش سطح MAC در شیر شتر افزایش یافته ولی در شیر گاو چنین نیست. نتایج حاصل نشان می­دهد که MAC در تجزیه چربی شیر شتر نقش­آفرینی می­کند. ترکیب مواد معدنی به طور معنی­داری تحت تأثیر SCC در شیر شتر واقع می­شود. ترکیب شیر تحت تأثیر تعداد دوره شیردهی در هر دو گونه قرار نمی­گیرد. سطح کل جامدات شیر، کلسیم و سدیم در شیر شتر همگام با پیشرفت دوره شیردهی، کاهش می­یابد. Manuscript profile -
Open Access Article
580 - Study the effect of cellular dams on upstream conditions of rivers by using the HEC-RAS model (case study: Mared cellular dam on the karoon river)
Mohammadamin Gandomi sara Amirzadeh Nooredin BazgirTides are affected by complex tidal hydraulic conditions. This study is the effect of constructing an upstream cell dam of Bahmanshir on Karun river from Ahvaz hydrometric station as an upstream border to Hafar three-way as a downstream model boundary. HEC-RAS model has MoreTides are affected by complex tidal hydraulic conditions. This study is the effect of constructing an upstream cell dam of Bahmanshir on Karun river from Ahvaz hydrometric station as an upstream border to Hafar three-way as a downstream model boundary. HEC-RAS model has been used to model river conditions in this research. The software output results showed that after the construction of the dam, the trend of changes in the upstream station changed drastically, so that the water level values in Ahvaz, Darkhovin, upstream of the cell dam were measured 4.5, 8, 12 meters, respectively. شد. The average flow velocities in Ahvaz, Darkhovin, upstream and downstream sections of the cell dam are 1.24, 0.87, 1.53, 1.24 m / s, respectively, and the flow velocity after construction and location of thشThis study is the effect of constructing an upstream cell-dam of Bahmanshir on Karoon river from Ahvaz hydrometric station as an upstream border to Hafar three-way as a downstream model boundary. HEC-RAS model has been used to model river conditions in this research. The software output results showed that after the construction of the dam, the trend of changes in the upstream station changed drastically, so that the water level values in Ahvaz, Darkhovin, upstream of the cell dam were measured at 4.5, 8, 12 meters, respectively. The average flow velocities in Ahvaz, Darkhovin, upstream and downstream sections of the cell dam are 1.24, 0.87, 1.53, 1.24 m / s, respectively, Manuscript profile -
Open Access Article
581 - Hormonal priming to overcome drought stress and aging damage in groundnut seed (Arachis hypogaea L.)
Hossein Reza Rouhi Ali Sepehri -
Open Access Article
582 - The role of phenolic compounds in growth improvement of cultured tobacco cells after exposure to 2-D clinorotation
Maryam Soleimani Faezeh Ghanati Zahra Hajebrahimi -
Open Access Article
583 - Enhancement of salt tolerance in black bean variety (Phaseolus vulgaris L.) by silicon nutrition
Fatemeh Heidarian Parto Roshandel -
Open Access Article
584 - Cell suspension culture of yew: an alternative method of taxol production
raheleh gorzi -
Open Access Article
585 - Fuzzy Inference System Approach in Deterministic Seismic Hazard, Case Study: Qom Area, Iran
Atena-Sadat Chavoshy Seyyed Mohammad-Reza Lajevardi Nadia Tahernia -
Open Access Article
586 - A New Design for Two-input XOR Gate in Quantum-dot Cellular Automata
Hossein Khademolhosseini Yaser Nemati -
Open Access Article
587 - Design and Analysis of a Fault Tolerant 3-Input Majority Gate in Quantum-dot Cellular Automata
Somayyeh Jafarali Jassbi Farzaneh Jahanshahi Javaran Hossein Khademolhosseini Amir Sabbagh Molahosseini -
Open Access Article
588 - A Full Adder Cell Based on MOSFET Technology to apply in Arithmetic circuits
Mokhtar Mohammadi Ghanatghestani Fatemeh Mohammadi Ghanatghestani -
Open Access Article
589 - Time-Distance Optimal Trajectory Planning For Mobile Robots On Straight And Circular Paths
Hossein Barghi Jond Adel Akbarimajd Nurhan Gursel Ozmen -
Open Access Article
590 - Designing and Implementing a Fast and Robust Full-Adder in Quantum-Dot Cellular Automata (QCA) Technology
Hojat-allah Bandani Sousan Mohammad Mosleh Saeed Setayeshi -
Open Access Article
591 - Simulation of Landuse Changes and Urban Dynamics using CA-Markov Hybrid Model Case Study: Maragheh City
Hoshang sarvarIn recent decades, along with urbanization, various models have been used to urban growth prediction. In this regard, Urban models based on the automata technique have emerged under the paradigm of a self-organizing system, with cellular automata (CA) being the simplest MoreIn recent decades, along with urbanization, various models have been used to urban growth prediction. In this regard, Urban models based on the automata technique have emerged under the paradigm of a self-organizing system, with cellular automata (CA) being the simplest but most popular in action What happens to each grid cell is defined by a transition rule or transition rules.If the transition rule requires that the state of a grid cell is only dependent on its state at a previous time step, such a model is called a Markov model, and is not considered a CA model. Cellular automata models have one additional feature: the transition rules operate on cells based on the local neighborhood of those cells. In this research, the spatial expansion of Maragheh city was simulated using Cellular automata- Markov chain hybrid model. Satellite images (Landsat) were used for land cover mapping, urban growth monitoring, and modeling land cover changes. Results represent high efficiency of Cellular automata- Markov chain in the urban spatial growth simulation. In the past three decades,development trend of Maragheh city has been more towards barren lands.According to the output of the model,this trend will continue over the next 17 years. So that, the city will be expended due to the transition of barren lands cells state to urban cells state,and 774 hectares from surrounding barren lands will be converted to urban lands. However, with continue of the previous trend, nearly 417 hectares of good agricultural lands will also change to urban lands. Manuscript profile -
Open Access Article
592 - Measuring the Effective Variables on Urban Expansion and Physical Development Simulation of Hamadan City Using Integrated Model of Cellular automata, Logistic Regression and Markov Chain
Saeid Hajibabaei keramatollah ziari kianoosh zakerhaghighiUrban development and irregular migration of rural population to urban areas are significant phenomena that have damaged agricultural lands, natural landscapes, and public open spaces. This issue doubles the need for informed guidance and spatial organization to better MoreUrban development and irregular migration of rural population to urban areas are significant phenomena that have damaged agricultural lands, natural landscapes, and public open spaces. This issue doubles the need for informed guidance and spatial organization to better understand the processes of urban development for future planning. The present study aimed to evaluate the growth of Hamedan city from 1996 to 2019 and then simulate until 2041. The research method is descriptive-analytical, and the cellular automation model was used to simulate physical development, and logistic regression was applied to analyze the impact of different variables on physical growth and the Markov chain was used to analyze user changes. The validity of Landsat satellite images is also evaluated with respect to the kappa value and acceptable overall accuracy. The results indicate that city center and agricultural land variables with ROC of 0.873 and 0.881, respectively, had the most impact on Hamadan urban growth during the last 23 years. The area of urban areas in 1996 was doubled compared to the year 2011, and almost 2.5 times more than in 2019. On the other hand, population growth increased 1.48 times over the past 23 years. This indicates that the growth rate of urban areas exceeded the population growth rate in Hamadan. The results of the model evaluation indicate that the integrated model is able to provide a precise understanding of urban processes and developments such as evaluating past developments and predicting directions and rates of future physical development. Manuscript profile -
Open Access Article
593 - Evaluation and Prediction of Spatial Changes and Urban Growth Using Remote Sensing (Case Study: Qorveh City)
Ebrahim Sami pooran karbasi Peyman Karimi mahtab sanginabadiToday Over the past few decades, the growth of urban societies and population growth have led to the spread of distorted cities into separate regions with its original texture and its development towards agricultural land and its surroundings. This unplanned development MoreToday Over the past few decades, the growth of urban societies and population growth have led to the spread of distorted cities into separate regions with its original texture and its development towards agricultural land and its surroundings. This unplanned development leads to land use changes in the periphery of the city. In the past few decades, the city of Qorveh has encountered with the development of urban and peri-urban settlements, which caused changes in the land use of the city of Qorveh and its surrounding areas. Analysis of land use change in Qorveh city can be effective in planning for future development of the city. Therefore, to attempted to estimate and determine land use change trends, Landsat satellite images with TM, ETM and OLI sensors were used for the three time periods of 1986, 2000 and 2018. These images were categorized, validated and detected by the Neural Network method to five floors; urban lands, arable lands, dry lands, water zones and Bayer lands. Finally, Markov Autoclave was used to calculate land use changes in Qorveh city for 2031. The results indicate that, continued land use change would result in the degradation of agricultural land use. Manuscript profile -
Open Access Article
594 - ارزیابی فعالیت های ضد میکروبی و سمیت سلولی عصاره های متانولی برگ گیاه Sansevieria zeylanica (L.) Willd. روی سرطان سینه در انسان، لاین های سلولی MDA-MB-231
S. Rajashekara S. Chudamani S. Rautela Sharvani Hegde S. Swaroopaگیاه Sansevieria zeylanica یک گونه علفی چند ساله مناطق خشک است که در قسمت­های گرمسیر و نیمه گرمسیر دنیا پراکندگی دارد. این گیاه، یک گیاه شگفت­انگیز دارویی است و مزایای زیادی دارد. هدف این مطالعه تعیین فعالیت­های سمیت سلولی در سرطان سینه در انسان روی لاین­ Moreگیاه Sansevieria zeylanica یک گونه علفی چند ساله مناطق خشک است که در قسمت­های گرمسیر و نیمه گرمسیر دنیا پراکندگی دارد. این گیاه، یک گیاه شگفت­انگیز دارویی است و مزایای زیادی دارد. هدف این مطالعه تعیین فعالیت­های سمیت سلولی در سرطان سینه در انسان روی لاین­های سلولی MDA-MB-231 و نیز ارزیابی خاصیت ضد میکروبی با استفاده از عصاره برگ متانولی گیاه S. zeylanica است. آزمایش اصلی تعیین حساسیت میکروب­ها در برابر عصاره­های متانولی برگ گیاه S. zeylanica است. درصد بازدارندگی رشد اندازه­گیری شد و غلظت نمونه برای ممانعت از رشد سلول تا 50 درصد (IC50) برای درصد زنده­مانی تعیین شد. عصاره­های برگی بدست آمده از گیاه S. zeylanica روی لاین­های سلولیMDA-MB-231 سرطان سینه در انسان اثر سمیت سلولی نشان دادند. شاخص IC50 (78/1167 میکروگرم در میلی­لیتر) پس از تیمار 24 ساعته روی این لاین­ها بدست آمد. افزایش مرگ سلولی روی لاین­های MDA-MB-231 با افزایش غلظت عصاره نشان می­دهد که عصاره متانولی برگ این گیاه فعال است. برای اولین بار، ما تلاش کردیم تا خصوصیات بیولوژیکی عصاره برگ متانولی گیاه S. zeylanica را ارزیابی کنیم. نتایج حاصل کاربرد درمانی را تایید کرد و می­تواند برای کاربرد وسیع به­عنوان ماده­ای ضد میکروب، مدرک معتبری باشد. در این مطالعات نتایج غربال­گری فعالیت­های فایتوشیمیایی، ضد میکروبی و سمیت گیاه S. zeylanica تایید کرد که این گیاه می­تواند به­عنوان منبع گیاهی طبیعی مورد استفاده قرار گیرد. این گیاه می­تواند برای مصارف دارویی و داروشناسی در مقیاس وسیع و بصورت صنعتی استفاده شود. Manuscript profile -
Open Access Article
595 - Use of Palm Waste Cellulose as a Substitute for Common Growing Media in Aglaonema Growing
M. BasiratIn order to evaluate the possibility use of palm waste cellulose as a substitute substrate for growing pot plants, an experiment was conducted in completely randomized block design with 6 replication and six treatments on Aglaonema sp. The treatments were 5 levels inclu MoreIn order to evaluate the possibility use of palm waste cellulose as a substitute substrate for growing pot plants, an experiment was conducted in completely randomized block design with 6 replication and six treatments on Aglaonema sp. The treatments were 5 levels including 0, 25, 50, 75 and 100 palm celluloid wastes mixed with different rates of some amendments such as peat, coconut coir, perlite, vermiculite, rice husk and sugarcane waste compost. The trial was conducted in a research greenhouse at certain environmental condition during 14 month. Before experiment, the chemical and physical properties of organic substrates were measured. To determine superior media the vegetative indexes were measured and data statistically analyzed. Results showed that the palm celluloid wastes had significant impact on the growth and total dry weight of plants that grown in mixing media in comparison with peat and peat- perlite potting media. Also peat and coir had not significant differences in most growth indices but palm celluloid wastes had greater increase in plant dry weight if it used as a 50-50 v/v percent mixing amendment in all treatments. Data indicated that palm celluloid wastes can be used as a media individually, and also as an amendment for other media such as sugarcane compost. Manuscript profile -
Open Access Article
596 - اثر سایکوسل و سایز گلدان بر رشد رویشی و گل دهی آهار (Zinnia elegans)
صدف طاهرپذیر داوود هاشم آبادی گل آهار به علت داشتن تنوع رنگ و طول دوره گلدهی، از گیاهان زینتی بسیار زیبا و جذاب میباشد. به منظور بررسی اثر سایکوسل و سایز گلدانبر رشد رویشی و گلدهی آهار، آزمایش در قالب فاکتوریل بر پایه طرح کاملا تصادفی با دو فاکتور سایکوسل در 3 سطح More گل آهار به علت داشتن تنوع رنگ و طول دوره گلدهی، از گیاهان زینتی بسیار زیبا و جذاب میباشد. به منظور بررسی اثر سایکوسل و سایز گلدانبر رشد رویشی و گلدهی آهار، آزمایش در قالب فاکتوریل بر پایه طرح کاملا تصادفی با دو فاکتور سایکوسل در 3 سطح (0، 1000و2000 میلیگرم در لیتر) و سایز گلدان در 4 سطح (10، 12، 14 و 16 سانتیمتر) با 12 تیمار و3 تکرار انجام شد. نتایج اثر متقابل نشان داد سایکوسل و سایز گلدان تاثیر معنی داری بر تمام صفات مورد بررسی داشته است و تیمار سایکوسل 2000 میلیگرم در لیتر درگلدان 12سانتیمتر کمترین ارتفاع بوته و گلدانهای سایز 16 سانتیمتر با سایکوسل 1000 میلیگرم در لیتر و بدون استفاده از سایکوسل بیشترین ارتفاع بوته را داشتند. بیشترین دوره گلدهی در گلدان سایز 14 سانتیمتر با 1000 میلیگرم در لیتر سایکوسل بود که تفاوت محسوسی با گیاهان مربوط به گلدان سایز 16 سانتیمتر در هر سه غلظت سایکوسل نداشت. کمترین دوره گلدهی آهار در گلدان سایز 10 سانتیمتر در هر سه غلظت سایکوسل بهدست آمد. آهار کاشته شده در گلدان سایز 10 سانتیمتر بدون سایکوسل دارای کمترین وزن تر و گلدان سایز 14 سانتیمتر بدون سایکوسل دارای بیشترین وزن تر ریشه بودند. به طور کلی گلدانهای سایز 14 و 16 در ترکیب با سایکوسل 1000 میلیگرم در لیتر، برترین تیمارها بودند. Manuscript profile -
Open Access Article
597 - انتخاب بستر کشت و روش تغذیه مناسب برای دستیابی به رشد مطلوب آروکاریای زینتی
هاجر عاشورزاده علی محمدی ترکاشوند علی محبوب خمامیبه دلیل عدم دانش علمی اثبات شده در به­کار­گیری بستر کشت و روش بهتر تغذیه، تعیین مناسب­ترین بستر کشت و روش تغذیه برای این گیاه از اهمیت فراوانی برخوردار است. این تحقیق جهت مقایسه روش متداول کوددهی واستفاده ازنانو کودآهن بررشدوعملکرد کاج مطبق با استفاده از &nb Moreبه دلیل عدم دانش علمی اثبات شده در به­کار­گیری بستر کشت و روش بهتر تغذیه، تعیین مناسب­ترین بستر کشت و روش تغذیه برای این گیاه از اهمیت فراوانی برخوردار است. این تحقیق جهت مقایسه روش متداول کوددهی واستفاده ازنانو کودآهن بررشدوعملکرد کاج مطبق با استفاده از 6 روش تغذیه و 3 بستر کشت متفاوت به صورت فاکتوریل در قالب طرح بلوک­های کامل تصادفی در 3 تکرار اجرا گردید. در این آزمایش نشاهای کاج آروکاریای زینتی پس از انتخاب نوع بستر به گلدان­های 4 لیتری انتقال یافتند و در گلخانه­ای مسقف با محدوده دمایی 17 تا 19 درجه سانتی­گراد در شب و 21 تا 23 درجه سانتی­گراد در روز نگهداری شدند. برخی از فاکتور­های رشد نظیر ارتفاع بوته، طول شاخه­های جانبی، قطر ساقه، طول ریشه، وزن تر اندام هوایی و ریشه، وزن خشک اندام هوایی و ریشه و وزن تر و خشک کل بوته و غلظت برخی عناصر غذایی در برگ اندازه­گیری شدند. نتایج نشان داد که از بین تیمارهای بستر کشت تیمار A3 (25% کوکوپیت+ 25% ورمی­کمپوست+ 25% خاک سبک+ 25% پرلیت) در اکثر صفات مورد ارزیابی (طول شاخه جانبی، وزن تر ریشه، وزن خشک ریشه، وزن خشک کل بوته، فسفر و آهن اندام هوایی)، مناسب­ترین بستر کشت برای نهال­های ریشه­دار این گیاه ارزشمند زینتی می­باشد. از نظر تغذیه با ترکیب­های مختلف کودی، تیمار B3 (فریلن)+20-20-20)NPK + فسفات دی آمونیم+ سولفات پتاسیم+ سولفات آمونیم) به دلیل داشتن اکثر عناصر و هم چنین منابع غذایی مورد نیاز در برخی صفات (طول شاخه جانبی، وزن تر اندام هوایی، وزن تر کل بوته، وزن خشک اندام هوایی و وزن خشک کل) دارای برتری می­باشد. نتایج نشان داد که تیمار A3B2 (25% کوکوپیت+ 25% ورمی کمپوست+ 25% خاک سبک+ 25% پرلیت) به همراه فسفات دی آمونیم، سولفات پتاسیم و سولفات آمونیم از نظر برخی فاکتور­های رشد نظیر وزن تر اندام هوایی و ریشه، وزن تر کل و وزن خشک کل نسبت به سایر تیمار­ها دارای برتری می­باشد و برای تولید کنندگان گیاهان زینتی قابل توصیه است. Manuscript profile -
Open Access Article
598 - Comparative Assessment of Leadership Style of Past Three Vice Chancellors of University of Agriculture, Makurdi
Gyanden Kughur Bini Adiel Dennis Tumba -
Open Access Article
599 - Communication Behaviour of Farmers with the Agricultural Extension Agents Using Cell Phone: A Case of Bangladesh
Mohammad Rahman Mohammed Uddin Md. Khan -
Open Access Article
600 - Provide a team learning model based on excellence management in the Islamic Republic of Iran
Aliasghar Mohammadpoor Negin Jabari Mohammad Salehithis research was aimed at providing a team learning model based on excellence management in the islamic republic of iran . the present study was applied with a practical goal and with the approach mixed with the exploratory design . the statistical population in the qu Morethis research was aimed at providing a team learning model based on excellence management in the islamic republic of iran . the present study was applied with a practical goal and with the approach mixed with the exploratory design . the statistical population in the qualitative part consisted of 18 scientific experts and the experience of the naja force that were selected by a targeted sampling method and considering the saturation rule . in the quantitative section , the statistical population of the quantitative part consisted of thousands of naja managers . the grounded theory method is used for qualitative data analysis . in order to analyze qualitative data , the foundation data method has been used . in the deductive statistics section , the kolmogorov - smirnov test was used to investigate the normality of the data from the sample t test and to test sample adequacy of the sampling sample from KMO test , Bartlett and model design using structural equation model . the results showed that with respect to the meaningful and positive coefficients of the coefficients , we can say that all aspects have positive effect on management of organizational excellence and team learning . The largest amount of t corresponds to the dimensions of organization ( and organizational work and diversity in the financial and human resources ) and the least of the dimensions ( compliance with the organization and the smart education ) Manuscript profile -
Open Access Article
601 - The relationship between the amount of new media and the younger generation's commitment to social values (Emphasize the study of Islamic Azad University of Tabriz, East Azarbaijan Science and Research)
منصور ساعی سونیا وطنیThe main objective of this study is "important tool to study the relationship between new media (mobile phones) and the younger generation's commitment to social values" is. This study is the first study to focus Brmtalh students of Islamic Azad University of Tabriz, Ea MoreThe main objective of this study is "important tool to study the relationship between new media (mobile phones) and the younger generation's commitment to social values" is. This study is the first study to focus Brmtalh students of Islamic Azad University of Tabriz, East Azerbaijan Province Science Research has been done. The definitions of the enjoyment, commitment, social values, as well as new media offer and The theory explain Howe's views and values of the social media including cultivation theory, the use and satisfaction, and views .... Jmyzlal, Gerbner and Inglehart and Johnson) as well as internal and external perspectives were discussed. Research among 368 graduate students of Islamic Azad University, Science and Research Branch, Tabriz, East Azerbaijan, which was conducted between 22 and 40 years of age. In this method utilizes a questionnaire survey and research data collection is required. The results showed that the high rate of mobile phone use is increasing importance of the criteria in mate selection. The increasing importance of mobile media usage and social relations between the sexes increases. The rise of mobile phone use increases the importance of responsibility among students. The rate increases the importance placed Particularists added. It can be said as a media phone-cell mass audience Importance has added some social values. Manuscript profile -
Open Access Article
602 - Securing social media: interaction with celebrities as a strategy for preventing dysfunctional behavior of online users
Amirhossein Zarandouz Zahra Alipour darvishi Zohreh Dehdashti Shahrokh Mohammd HaghighiAbstract Background and purpose: In recent years, social media have made profound changes in the behavior of users. Along with the normal behavior in this type of media, misbehavior is happening and the management of such behavior has become a challenge. Therefore, the MoreAbstract Background and purpose: In recent years, social media have made profound changes in the behavior of users. Along with the normal behavior in this type of media, misbehavior is happening and the management of such behavior has become a challenge. Therefore, the aim of this research is how governance systems can use the capacity of the famous to manage this space. Research method: This research was conducted with the foundation data approach. A semi-structured interview was conducted with 13 social media experts until theoretical saturation. Maxwell's 5-factor framework was used for the validity and reliability of the measurement tool. Findings: The coding process was done in 5 sections and 8 main categories. The category of antecedents includes sociological and psychological factors, post-futures include individual, interpersonal and social factors, context includes social media, and conditions include interaction with people, and conditions include environmental considerations. Conclusion: The results indicate that the most important propositions in controlling misbehavior by namesakes are educational interaction, increasing the threshold of tolerance, public security, social capital, and national cohesion, which need to be paid attention to it. Manuscript profile -
Open Access Article
603 - Warning and Rapid Estimation of Earthquake Damage (WARED) system: A New method for Rapid Determination of Earthquakes Damage and Fatality in IRAN
Abbas Kangi -
Open Access Article
604 - Explaining the human capital excellence model in Iran's education and training
kazhal shahriari yahya dadash karimi kaveh teimoornejad Dariush GholamzadehThe aim of the current research is to explain the human capital excellence model in Iran's education and training. This research is of applied type, and in terms of method, descriptive-correlation. The statistical population of the research includes all staff members of MoreThe aim of the current research is to explain the human capital excellence model in Iran's education and training. This research is of applied type, and in terms of method, descriptive-correlation. The statistical population of the research includes all staff members of the Education and Training Organization, numbering 200 people, of which 132 people were selected as a statistical sample based on Morgan's table and selected by simple random. Data were collected through a researcher-made questionnaire. The indicators and items of human capital excellence were tested using the structural equation model. Examining the fit indices of the model indicates that the structural model of the research has a good fitting condition. According to the findings of the research, the validity of all indicators and items of human capital excellence was confirmed. And the results showed that the t value of human capital excellence indicators in Iran's education and training is more than its critical value at the level of 5 percent (1.96) and therefore the validity of human capital excellence indicators and items was confirmed. Also, the results showed that in terms of the greatest effect of the subscale of the excellence of human capital in education and training, it belongs to the components of the content (knowledge-cognitive) and individual (psychological) components with the values of 0.730 and 0.710 on the excellence of human capital in education and training. is. And the lowest direct effect of human capital excellence in education is related to the metacognitive component of 0.350. Manuscript profile -
Open Access Article
605 - Organizational Excellence Model by Examining the Effects of Human Resources Competencies in the Marketing of Educational Services
Saeed Talebi Seyyed Mahmoud Shabgoo Monsef kambiz shahroodi Farzin FarahbodUNESCO considers education to be the key to the development of societies. The current growing competitive environment also made educational institutions compete. Due to the importance of educational institutions that play a fundamental role in society's development, it MoreUNESCO considers education to be the key to the development of societies. The current growing competitive environment also made educational institutions compete. Due to the importance of educational institutions that play a fundamental role in society's development, it is necessary to select competent human resources in these institutions. The current research aims to investigate the effect of human resources competencies on the educational marketing approach in the Organizational excellence model and to present the Organizational excellence model based on competence in educational institutions. The current research is operational in terms of purpose and descriptive in correlation type. Its statistical community consists of experts and specialists in the specialized education field in the water and electricity industry of Iran in the technical education institute of the water and electricity industry number of 60 people; from this population, a sample of 50 people was chosen. The collected data, a questionnaire derived from the criteria and sub-criteria of the EFQM 2020 standard model, was used, whose reliability was determined by calculating Cronbach's alpha formula. The construct questionnaire validity was also selected by confirmatory factor analysis. Smart-PLS statistical software used the partial least squares method to analyze the obtained data and statistical confirmation of the model and its validation. The path coefficients' results indicate a significant relationship between the variables of human resource competence and organizational excellence. Also, the fit indices of the model suggest that the presented model has suitable fitness. Manuscript profile -
Open Access Article
606 - The Effect of Green Human Resource Management and its Practices on Organizational Performance and Excellence with the Mediation of Green Innovation
Saeid Landaran Esfahani Mina Omrani Ghajavarestani Babak MoaleminiaWhen the goals of the organization and human capital are aligned, the green management of human capital by creating constructive communication and internalizing commonalities can create holographic properties in the organization and increase organizational commitment. B MoreWhen the goals of the organization and human capital are aligned, the green management of human capital by creating constructive communication and internalizing commonalities can create holographic properties in the organization and increase organizational commitment. By encouraging learning and question-oriented training, green management increases creativity and, as a result, improves the organization's performance. In this research, a cross-sectional research was conducted based on a questionnaire to collect data from a sample of 207 people, who are employees of Zob Ahan Isfahan Company. Structural equation modeling method and Smart PLS software were used to test research hypotheses. The results of the research indicate that green human resource management and its methods are effective on green organizational creativity and commitment, as well as culture. Also, the influence of commitment and creativity and culture in innovation has also been confirmed. In addition, the results show that the presence of green innovation in the organization can have a significant impact on organizational performance and excellence. Manuscript profile -
Open Access Article
607 - The effects of designing quality management technical standards on product maturity and excellence
Hojjat Moeeni Mehrdad Javadi Sadigh Raissi -
Open Access Article
608 - Robust optimization of a mathematical model to design a dynamic cell formation problem considering labor utilization
Moghadaseh Vafaeinezhad Reza Kia Parisa Shahnazari-Shahrezaei -
Open Access Article
609 - Development of a cell formation heuristic by considering realistic data using principal component analysis and Taguchi’s method
Shailendra Kumar Rajiv Kumar Sharma -
Open Access Article
610 - Developing a cellular manufacturing model considering the alternative routes, tool assignment, and machine reliability
Sayyed Mahdi Sadat Khorasgani Mahdi Ghaffari -
Open Access Article
611 - Monitoring the censored lognormal reliability data in a three-stage process using AFT model
Azam Goodarzi Amirhossein Amiri Shervin Asadzadeh -
Open Access Article
612 - An archived multi-objective simulated annealing for a dynamic cellular manufacturing system
Hossein Shirazi Reza Kia Nikbakhsh Javadian Reza Tavakkoli-Moghaddam -
Open Access Article
613 - Adaptive call admission control and resource allocation in multi server wireless/cellular network
Madhu Jain Ragini Mittal -
Open Access Article
614 - A multi-objective model for designing a group layout of a dynamic cellular manufacturing system
Reza Kia Hossein Shirazi Nikbakhsh Javadian Reza Tavakkoli-Moghaddam -
Open Access Article
615 - Stochastic extension of cellular manufacturing systems: a queuing-based analysis
Fatemeh Fardis Afagh Zandi Vahidreza Ghezavati -
Open Access Article
616 - A genetic algorithm for a bi-objective mathematical model for dynamic virtual cell formation problem
Mostafa Moradgholi Mohammad Mahdi Paydar Iraj Mahdavi Javid Jouzdani -
Open Access Article
617 - A stochastic model for the cell formation problem considering machine reliability
Bahman Esmailnezhad Parviz Fattahi Amir Saman Kheirkhah -
Open Access Article
618 - Mathematical model for dynamic cell formation in fast fashion apparel manufacturing stage
Gayathri Perera Vijitha Ratnayake -
Open Access Article
619 - Dynamic cellular manufacturing system considering machine failure and workload balance
Masoud Rabbani Hamed Farrokhi-Asl Mohammad Ravanbakhsh -
Open Access Article
620 - Two-machine robotic cell considering different loading and unloading times
A.M Kimiagari H Mosadegh -
Open Access Article
621 - A multi agent method for cell formation with uncertain situation, based on information theory
N Javid A Makui -
Open Access Article
622 - Combined Porcelain Ceramic and Recycled Concrete Aggregates Used as Replacement for Coarse Aggregates in Concrete
Sayed Behzad Talaeitaba Maedeh Dehghani -
Open Access Article
623 - Investigate the effect of different Forta Ferro fiber concentrations on the tensile strength of concrete, an experimental study employing the Barcelona and double punch tests
Ehsanollah Zeighami mohsen ghomi mohammad mirhosseini s lajevardiConcrete is highly vulnerable to tensile stress, and the use of rebar is not always practical or cost-effective. Forta Ferro fibers offer an alternative solution for enhancing the tensile strength of concrete. In this study, 36 cylindrical and 36 cubic samples were test MoreConcrete is highly vulnerable to tensile stress, and the use of rebar is not always practical or cost-effective. Forta Ferro fibers offer an alternative solution for enhancing the tensile strength of concrete. In this study, 36 cylindrical and 36 cubic samples were tested using compressive strength, Barcelona, and double punch tests. The samples were aged for 28 days and contained 0, 1, 2, or 3 kg/m3 of Forta Ferro fibers. The results showed that adding 1 to 3 kg/m3 of Forta Ferro fibers to the concrete increased the 28-day tensile strength (BCN test) by 8.40% to 9.04% in cylindrical samples and 8.71% to 8.93% in cubic samples. Similarly, the 28-day tensile strength (DPT) increased by 6.81% to 9.42% in cylindrical specimens and 3.92% to 6.69% in cubic specimens when Forta Ferro fibers were added. The proposed Chen coefficient of 1.08 is suggested as the correction factor for the Forta Ferro fibers. Manuscript profile -
Open Access Article
624 - Cellular Automata in Optimum Shape of Brick Masonry Vault under Dynamic Loads
Kaveh Kumarci Afsaneh Banitalebi Dehkordi Pooya Khosravyan Dehkordi -
Open Access Article
625 - Measuring the relationship between workplace spirituality and organizational excellence in the National Library and Archives of Iran
Fatemeh Nooshinfard Azita KhodabakhshPurpose: The present study examine the relationship between Workplace Spirituality and organizational excellence in the National Library and Archives of the Islamic Republic of Iran. Methodology: Analytical survey method, and research population consists of 160 manager MorePurpose: The present study examine the relationship between Workplace Spirituality and organizational excellence in the National Library and Archives of the Islamic Republic of Iran. Methodology: Analytical survey method, and research population consists of 160 managers and librarians working in national library of Iran. The Questionnaire to measure spirituality in the workplace has been used the Milliman Questionnaire and has been used to determiningthe spirituality in three levels, individual, group and organizational. To set factors of excellence has been used standardized questionnaire that contains nine main criterions: Leadership, People, Policy and Strategy, Partnerships and Resources, Processes, People Results, Customer Results, Society Results and Key Performance Results. The data analysis has been done bySPSS software. Findings: In the case of spirituality at work the highest rate belonged to the “Group Level” with the average 24.04 and the lowest rate also belonged to the “Individual level” with an average of 22.5. Also, the F-test between the two groups in the field of Librarians and Non-librarians shows that there is a difference. Conclusion: There is a significant relationship between the level of organizational excellence and spirituality in the workplace in the National Library. Manuscript profile -
Open Access Article
626 - The effect of umbilical cord stromal cells and chicory extract on the repair process of amputated sciatic nerve in male Wistar rats (Behavioral and electrophysiological study).
amirhosin fazlali Hayati Rodbari nasim gholamreza Kaka kazem parivar homayoon sadraiBackground and purpose: In this study, the therapeutic effect of umbilical cord blood cells with chicory extract on repair of severed sciatic nerve in adult male Wistar rats was evaluated by behavioral, electrophysiological study.Materials and Methods: After sciatic ner MoreBackground and purpose: In this study, the therapeutic effect of umbilical cord blood cells with chicory extract on repair of severed sciatic nerve in adult male Wistar rats was evaluated by behavioral, electrophysiological study.Materials and Methods: After sciatic nerve amputation, adult male rats were randomly divided into 4 groups of 7.Healthy rats, rats with sciatica without treatment intervention, rats with umbilical cord blood cells treated with chicory extract at the site of amputation, rats with umbilical cord blood cells injected at the site of injury.The rate of recovery was assessed by sensory motor activity of the sciatic nerve, electrophysiological studies.Results: Sciatic nerve motor evaluation, no control group returned to normal in the eighth week, cell therapy group was restored with chicory extract in the eighth week. The level of AMP in the eighth week after the restoration of the cell therapy group with a gentle slope indicates the recovery process of the cell therapy group.Counting the number of nerve fibers at an area of 1000 μm, the number of nerve fibers in the cell therapy groups increased in the eighth week after repair, compared with the control group and the PLGA membrane group. By the end of the eighth week, the sciatic nerve index (Hot Plate test), the healing process of the cell therapy group with chicory extract was more evident to other groups.Conclusion: Cord blood cell transplantation repairs sciatic nerve and chicory extract along with umbilical cord blood cells accelerates sciatic nerve repair. Manuscript profile -
Open Access Article
627 - Induction Of NMRI Mice Mesenchymal Stem Cell Differentiation Into Endothelial Progenitor Cells By Placental Extract
maryam sadat Nezhadfazel Kazem Parivar nasim HAYATI mitra heydariStem cells are undifferentiated pluripotent cells, can produce different tissues and organs of the body. Stem cells have two features, self-renewal and differentiation. Of the most important adult stem cells are mesenchymal stem cells. These cells are capable of prolife MoreStem cells are undifferentiated pluripotent cells, can produce different tissues and organs of the body. Stem cells have two features, self-renewal and differentiation. Of the most important adult stem cells are mesenchymal stem cells. These cells are capable of proliferation and differentiation with induction in the presence of variety of growth factors. Since the placenta extract contains a large amount of VEGF, therefore placenta extract was used to induce the differentiation of omentum mesenchymal stem cells.The omentum mesenchymal stem cells were separated and cultured and cell-specific markers CD90, CD44, CD73, CD105 and CD34 markers were tested by flowcytometry on them. The extract of the placenta was prepared and after the MTT test, we selected a 20% viability percentage. After 21 days the presence of mesenchymal stem cells omentum in medium and 20 percent of placenta extract, mesenchymal cells were differentiated into progenitor endothelial cells. The expression of CD90, CD73 and CD105 markers was negative and expression of CD31, FLK1 and CD34 markers was positive. G1 phase of the cell cycle in 2st week of prolonged, compared to the control group, this result showed that the cells were exited from the proliferative phase into differentiation phase.Conclusion: Omental mesenchymal cells in adjacent to the placenta extract, differentiate into endothelial progenitor cells. Manuscript profile -
Open Access Article
628 - Comparison of Rosemary (Rosmarinus officinalis L.) hydroalcoholic extract on the viability of head and neck cancer cells Line HN5 and neuronal progenitor cells of Mouse
Tayebeh Mohammadi Elham HoveiziCancer is a main health problem worldwide and the number of cancer patients is increasing annually. Cancer treatment needs new anticancer medicines because of drug resistance. Rosemary is one of the herbal medicines which its anti-cancer effects have been reported. The MoreCancer is a main health problem worldwide and the number of cancer patients is increasing annually. Cancer treatment needs new anticancer medicines because of drug resistance. Rosemary is one of the herbal medicines which its anti-cancer effects have been reported. The purpose of the present study was to evaluate rosemary extract effect on HN5 cancer cells viability in comparison with neuronal progenitor cells(NPCs). NPCs were obtained from 17 days pregnant mice by enzymatic digestion method. These cells and HN5 cells were treated with 50, 100, 200 and 500 µg/ml of rosemary extract for 24, 48 and 72 hours. Their viability was measured using MTT assay. Results showed that rosemary extract decreased HN5 cells viability in 100, 200 and 500 µg/ml concentrations which were significant in comparison with NPCs. The extract increased NPCs proliferation rate in 50 and 100 µg/ml concentration and decreased their viability in 500 µg/ml concentration. Rosemary extract can decrease cell viability as a dose and time dependent manner but this effect also depends on the cell type such as its killing effect on cancer cells was more. Manuscript profile -
Open Access Article
629 - New Hopes in fertility preservation in women with canser (review article)
Seyedeh Fatemeh Siadat Rouhollah FathiRecent advances in cancer diagnosis and treatment such as radiotherapy, chemotherapy and bone marrow transplantation have increased life expectancy in these patients. Toxic substances and ionizing radiation threaten endocrine activity and reproductive cycle, causing los MoreRecent advances in cancer diagnosis and treatment such as radiotherapy, chemotherapy and bone marrow transplantation have increased life expectancy in these patients. Toxic substances and ionizing radiation threaten endocrine activity and reproductive cycle, causing loss of fertility and early ovarian failure (POF). Common approaches to treating fertility include ovarian Oophoropexy, oocyte and embryo freezing, and freezing of ovarian tissue and transplantation. Cryopreservation of the embryo and oocyte requires hormonal stimuli to increase the number of eggs, but delay the onset of cancer treatment and directly contribute to the development of hormone-dependent tumors. On the other hand, in the freezing of the embryo, there is a need for a sexual partner (the wife or sperm donor) and is not accessible to young girls and children. For this reason, in young patients, in order to preserve fertilization, ovarian tissue cultures and then transplantation are more useful. So far, various methods have been used in ovarian transplantation on different animal and human species. Each of these methods has some advantages and disadvantages. However, many unresolved issues remain with regard to maintaining fertility in cancer patients. On the other hand, hopefuls have been opened to preserve the fertility of cancer patients. The purpose of this study is to update the research on fertility preservation strategies and to summarize the progress made in this regard. Manuscript profile -
Open Access Article
630 - Cytotoxic Effect of Girard-T Reagent-based Schiff Bases and their Dimethyltin (IV) Complexes on Human Colon Cancer Cells
elham hoveizi zynab ansariaslDespite many efforts, no definitive treatment is yet knowing for cancer. Therefore, research on new compounds that have anti-cancer properties is especially important. The aim of this study is investigation the cytotoxic effect of Girard-T reagent-based Schiff bases and MoreDespite many efforts, no definitive treatment is yet knowing for cancer. Therefore, research on new compounds that have anti-cancer properties is especially important. The aim of this study is investigation the cytotoxic effect of Girard-T reagent-based Schiff bases and their complexes on HT29 cancer cells. HT29 cells was cultured in DMEM/F12 medium containing FBS 10% and antibiotics 1% then the effects of ligands and their complexes with the concentration of 0.1, 1 and 5 mg/ml were surveyed on these cells in 1, 2, and 3 days. Growth, proliferation and morphological changes were photographed using an inverted microscope. MTT assay and DAPI staining were used to quantify cell viability. With concentrations of 0.1, 1, and 5 mg/ml of [SnMe2(L2)] (the effective component) the survival were decreased to 34, 24 and 18% after 72h(P<0.05). Encountering cells with complex caused to induce apoptosis in relation with concentration so that, the cell viability of cells treated with concentrations of 5 mg/ml (the effective concentration) of (H2L1) ،(H2L2) ،[SnMe2(L1)]،[SnMe2(L2)] was 22, 18, 29, and 22 respectivly after 72h and the highest apoptosis (82%) happened in 5mg/ml of SnMe2(L2). The synthetic components have a toxic and ant-proliferation effect on HT29 in relation with concentration. Manuscript profile -
Open Access Article
631 - Study of defense mechanism of microalgae Haematococcus pluvialis infected by Paraphysoderma sedebokerensis
Bahareh Nahidian Faezeh Ghanati Maryam Shahbazi neda Soltani Morteza GholamiIn the present study, the first early physiological responses of the green micro algae Haematococcus pluvialis during infection by chytrid Paraphysoderma sedebokerensis was studied. To this end, the palmeloid form of Haematococcus pluvialis was cultivated for two days i MoreIn the present study, the first early physiological responses of the green micro algae Haematococcus pluvialis during infection by chytrid Paraphysoderma sedebokerensis was studied. To this end, the palmeloid form of Haematococcus pluvialis was cultivated for two days in three media including the medium infected with chytrid (chyt) and the culture of chytrid infected (IBS) and uncontaminated (HBS) cells. Then, the activity of antioxidant enzymes, extracellular peroxide, and free intracellular enzymes were determined by UV/Vis spectrophotometry and HPLC techniques. The activity of superoxide dismutase, catalase, and peroxidase in the chytrid infected cells after 24, 24, and 48 h was 2.3, 6.7, and 2.6 times higher those of control. These values for the cells cultivated with the infected media after 12, 12, and 36 h was found to be 2.1, 2.5, and 2.6 times higher than control. The extracellular peroxide content in the algae cultivated with the contaminated media was nearly constant and about 4 fold of the other specimens; while those of chytrid infected cells was slightly increased from 1.3 to 1.8 μM during 48 h cultivation. Amino acids histidine, alanine, asparagine, aspatic acid, arginine, and methionine were of the highest and the phenylalanine and tryptophan were of the lowest content. These results can be attributed to the cells defense response to chytrid infection thorough enhancement of peroxide content and activation of antioxidative pathways. Manuscript profile -
Open Access Article
632 - Evaluation of cytotoxic effect of Ruta graveolens L. Hydro alcoholic extract in human cervical cancer cells (HeLa)
seyed milad mousavi jazayeri elahe ebrahimi Masoud parsaniaAbstract Introduction Cervical cancer is one of the most common cancers in women. In some cases, the lack of appropriate response to treatment with chemical drugs and the side effects of using synthetic drugs show necessary to achieve a natural drug that has minimal si MoreAbstract Introduction Cervical cancer is one of the most common cancers in women. In some cases, the lack of appropriate response to treatment with chemical drugs and the side effects of using synthetic drugs show necessary to achieve a natural drug that has minimal side effects. This study was evaluated effects of Hydroalcoholic extracts Ruta graveolens L. against of HeLa cell. Material and Methods HeLa cells were cultivated in Dulbecco’s Modified Eagle’s Medium (DMEM) supplemented with 10% fetal bovine serum. Preparation of extract were done by maceration technique. This study were assessed the effects of different concentrations (250, 500, 750, 1000 and 1500 μg/ml) of Ruta graveolens L. on the proliferation of HeLa cells at 24, 48 and 72 hours after treatment of cells with extract and medium containing 1% serum by Trypan blue and MTT methods. Finding The cytotoxic concentration 50% (CC50) of the extract was determined on HeLa cell 1500 ug/ml. The results showed that concentrations of 1000 ug/ml of Ruta graveolens L. extract, after 72 hours showed a significant decrease in the proliferation of HeLa cells compared with control. Conclusion: The results of this study showed Ruta graveolens L. extract can inhibit the proliferation of HeLa cells. Keyword: Cytotoxic effect, Ruta graveolens L. extract, HeLa cells. Manuscript profile -
Open Access Article
633 - Comparison of Ginger(Zingiber officinale) Hydroalcoholic Extract on the Viability of Cancer Cells and Embryonic Fibroblast Cells
Elham Hoveizi Tayebeh MohammadiLung cancer is the most common cause of cancer related death. Ginger is an edible and medicinal plant having important health benefits including anticancer activity. The aim of this study was evaluation and comparison of the effect of hydroalcoholic extract of ginger on MoreLung cancer is the most common cause of cancer related death. Ginger is an edible and medicinal plant having important health benefits including anticancer activity. The aim of this study was evaluation and comparison of the effect of hydroalcoholic extract of ginger on lung cancer cells and normal mouse embryonic fibroblasts. Human lung cancer cell line A459 and normal mouse embryonic fibroblasts were cultured in vitro and treated with different concentrations of ginger extract for 24, 48 and 72 hours. The MTT assay was used to determine cell viability. Ginger extract in concentrations of 1800 and 2000 µg/ml had killed both of cells at 72 hours after treatment and caused morphological changes in cells which were more obviously in cancer cells. Ginger extract in concentrations of 1000, 1200, 1400, 1800 and 2000 µg/ml killed cancer cells more than embryonic cells(P<0.05). Cytotoxicity effect of ginger on lung cancer cells was more than its effect on normal mouse embryonic fibroblasts and can be regarded as a safe anticancer medicine. Manuscript profile -
Open Access Article
634 - The effects of different concentrations of CaCL2 and MgSO4 on histological-cellular variation of microtubers in Solanum tuberosum In vitro conditions
zahra zare Alireza Iranbakhsh Mostafa EbadiThe potato (Solanum tuberosum L.) is one of the most important agricultural plants in the world. It is propagated predominantly by asexual methods. The traditional methods for asexual propagation of the plant faced important problems. Therefore, the seed tubers can be r MoreThe potato (Solanum tuberosum L.) is one of the most important agricultural plants in the world. It is propagated predominantly by asexual methods. The traditional methods for asexual propagation of the plant faced important problems. Therefore, the seed tubers can be replaced by micro tubers produced by tissue culture. The aim of this study is search about effect of different concentrations of CaCL2 and MgSO4 in media culture In vitro in histological - cellular variations of the microtubers. In this study solid and liquid MS media were used to prepare sterilized seedlings and micro tuberization.The concentrations of 0, 1/2, 1, 3/2 and 2 times more than standard concentrations of the mentioned compounds in MS medium were used in separate induction media . Induction was done in the alternating photoperiod. In order to the developmental and anatomical studies cross sections of microtubers was prepared and studied by light microscopy.The number of cell rows, the dimensions of the cells and the starch content of the parenchymal tissues of microtuber were analyzed. the results showed significant variations in histological features of the microtubers developed in media containing different concentrations of macronutrients. CaCL2 with concentrations of 0.5 to 1 time more than standard concentration in MS medium yielded maximum number of cell rows and maximum starch granules content. However, the presence of a minimum amount of magnesium is essential for the formation of the micro tubers. But there is no statistically significant effect on cellular changes of microtubers and starch content. Manuscript profile -
Open Access Article
635 - Evaluation of adhession and viability of endometrial stem cells-derived osteoblast-like cells cultured on PLGA/HA scaffold
mojdeh salehi jafar ai nasrin lotfibakhshaiesh shiva irani سمیه ابراهیمی باروقIntroduction: The engineered tissue structure includes three components: cells, signaling pathway and scaffold. The polylactide-co-glycolide/hydroxyapatite (PLGA/HA) has attracted much attention due to their optimal properties because of using PLGA polymer and hydroxyap MoreIntroduction: The engineered tissue structure includes three components: cells, signaling pathway and scaffold. The polylactide-co-glycolide/hydroxyapatite (PLGA/HA) has attracted much attention due to their optimal properties because of using PLGA polymer and hydroxyapatite. The aim of this study was to evaluate the biocompatibility effect of PLGA/HA scafffold on osteoblast differentiated from hEnSCs. We aimed to evallute the adhesin of cells on scaffolds. hEnSCs were isolated from human endometrium tissue and induced the osteogenic differentiation, then the differentiated cells were cultured on PLGA/HA synthetic scaffolds. A nanocomposite scaffolds based on PLGA/HA were fabricated by electrospinning methode and behavior of differentiated osteoblast cells was evaluated after seeding cells on this scaffold. Osteogenesis was investigated in terms of attachment, alkaline phosphatase activity and gene expression. Morphogenic of cells in scaffold was evaluated by SEM and biocampatibility of this scaffold was confirmed by MTT assay. The alkaline phosphatase activity confirmed osteoblast differentiation. SEM studies showed that the surface properties of scaffold were desirable and the cells had the ability to attach and proliferate better on the nanocomposite scaffolds. It has been shown that the nanocomposite scaffolds have appropriate properties to support the attachment of differentiated osteoblast cells. Manuscript profile -
Open Access Article
636 - Stereological study of changes of testicular tissue in Egyptian Fruit bat (Rousettus aegyptiacus) throughout the year
Farangis Ghassemi Esmat Abas FardDue to importance of bats in ecosystem and the limited information about reproduction of this useful organism, the spermatogenesis of the Egyptian Fruit bat (Rousettus aegyptiacus) was studied stereologically in three seasons, spring to autumn, as the first record. For MoreDue to importance of bats in ecosystem and the limited information about reproduction of this useful organism, the spermatogenesis of the Egyptian Fruit bat (Rousettus aegyptiacus) was studied stereologically in three seasons, spring to autumn, as the first record. For this purpose, 7 male bats were captured by mistnet in Sangtārashan Cave (Fars- Jahrom ), and transferred to the laboratory at the end of every season. After anesthetization and dissection of bats, their testicles were removed and fixed after measuring. The sections (5μm) were prepared from fixed samples and stained. The volume of studied parameters was determined by using Cavallier method, and seminiferous diameters and testicular cells number were measured with stereo Lite software. Obtained data were analyzed by Kruskal–Wallis, and compared by Friedman test. According to obtained results, the testicles were in the scrotum out of the body with significant difference of weight and volume in the left and right testis, and the maximum weight (0.7650± 0.19g) and volume (862± 0.41 mm3) were in spring. The germ cells and many sperm were observed in the lumens in all seasons. The diameter of seminiferous tubule were different (P<0.05) between spring (235/90±1.06 µm) and autumn (227.82±1.29 µm) were observed. Maximum mean number of spermatocyt (294.6×106), sertoli (11.59×106) and lydig (39.30×106) were estimated in spring and the lowest of them in autumn, but the maximum number of spermatid (284.2 ×106) were in autumn. According to these results, the peak of sexual activity of this bat species is in spring and summer. Manuscript profile -
Open Access Article
637 - Comparison of Apoptotic Effects of S14161 and Citrus limon Leaves Hydroalcoholic Extracts on Breast Cancer Cells MCF-7
elham hoveizi Kiavash Hoshmndi Saad Gooraninejad Mohammad Reza TabandehBreast cancer is a multifactorial disease in which genetics, hormonal factors and the interaction between individuals and the environment contribute to it. In the present study, we try to compare the effect of lime leaves extract and S14161 small molecule on apoptosis o MoreBreast cancer is a multifactorial disease in which genetics, hormonal factors and the interaction between individuals and the environment contribute to it. In the present study, we try to compare the effect of lime leaves extract and S14161 small molecule on apoptosis of MCF-7 breast cancer cells. Apoptotic effects of S14161 and hydroalcoholic extract of Lime leaves on MCF-7 cells were investigated using MTT method, the morphology of cells with acridine orange staining using the fluorescent microscope. The results showed that the S14161 and Lime leave extract decreases the survival rate and proliferation of MCF-7 cells in a time and dose-dependent manner. Based on the results of the MTT test, 10 μM concentration of S14161 and 6 mM concentration of Lime extract was determined within 24 hours as IC50 concentration of MCF-7 cells. Comparison of Lime extract and S14161 showed that the amount of small molecule cytotoxicity was higher than that of Lime leaves extract and there was a significant difference between survival percentage of cancer cells treated with S14161 and cells treated with lime leaves extracts on day 1, 3 and 5 (P <0.05). Also, there were significant morphological changes such as shrinkage and increasing size of vacuoles, cytoplasmic loss, nucleus pigmentation and fragmentation of chromatin in treated cancer cells. The specific effect of this inhibitor on cell growth, as well as the lack of observation of toxic effects to high concentrations, has been described as a major strategy for treating breast cancers. Manuscript profile -
Open Access Article
638 - Effect of aquatic garlic (Allium sativum L.) extract on the survival of breast cancer cells (MCF-7) and non-cancerous cells of mouse fibroblasts (L929)
Zahra Hassanzadeh Elmira Mikaeili Agah Asadollah Asadi Kobra Bagheri valmiGarlic has been known worldwide as a dietary constituent with many pharmacological effects in humans for centuries. The aim of this study was to compare the cytotoxicity effect of the aqueous extract of garlic on breast cancer cells (MCF-7) and non-cancerous normal cell MoreGarlic has been known worldwide as a dietary constituent with many pharmacological effects in humans for centuries. The aim of this study was to compare the cytotoxicity effect of the aqueous extract of garlic on breast cancer cells (MCF-7) and non-cancerous normal cells (L929). After culture and treatment of cells with different concentrations of extract for 24, 48 and 72 hours, the cell morphology was investigated by invert microscopy and the toxic effect of the extract was determined by MTT (3- 4, 5 dimethylthiazole 2-yl 5,2-diphenyl tetrazolium). Microscopic observations showed no change in both cell lines within 24 hours. These changes appeared after 48 and 72 hours in cancerous cells and increased after 72 hours, but no significant changes were observed in healthy cells. At the same time, the results of MTT showed that the mortality rate was significant at high doses at 24 and 48 hours (P <0.001), and in 72 hours it was very intense and survival rate reached 48% at the highest dose. However, at 24 and 48 hours, we did not see significant death in non-cancerous cells, but at higher doses of 4000 μg/ml in 72 hours, death increased significantly (P <0.001) but did not exceed 19%. Therefore, aqueous extract of garlic has a greater effect on breast cancer cells than normal cells, and can be used to prevent cancer or as a supplement to chemotherapy in the future. Manuscript profile -
Open Access Article
639 - The effect of glucose, sucrose, lactose carbon sources on the growth of Alcaligenes eutrophus for the production of polyhydroxybutyrate
atefeh farjadmanesh seyed ahmad ataeiBackground & Objectives: Polyhydroxyalkanates are a group of polymers that are produced by many bacteria when they enter the growing phase in the presence of mineral sources. The Objective of this study is investigattion of the different culture containing carbon so MoreBackground & Objectives: Polyhydroxyalkanates are a group of polymers that are produced by many bacteria when they enter the growing phase in the presence of mineral sources. The Objective of this study is investigattion of the different culture containing carbon sources of glucose, sucrose, lactose, combination of these carbon sources, on the growth of Alcaligenes eutrophus to produce biodegradable polymers of hydroxy butyrate-valerate. Materials & Methods: In this study Alcaligenes eutrophus was identified In order to producing of hydroxybutyrate-valerate and investigation of the effect of the different carbon sources on the production. To perform experiments, in fed-batch mode, acetic acid and propionic acid combination with acetic acid as a source of volatile fatty acid was added to the culture in a stepwise manner. The culture with inoculated bacteri were transferred to incubator at 32°C, 120 rpm and retention time of 72 hours, for to incubation and polymer production. Results: The results of this study showed that the source of glucose as carbon with acetic acid produced the highest amount of hydroxybutyrate-valerate (HB= 3.4860 g/l and HV=0.7940 g/l). Also, the lowest amount of hydroxybutyrate production (HB= 2.3124 g/l) is Because of using sucrose as the carbon source and the combination of acetic acid and propionic acid. Conclusion: The results showed that Alcaligenes eutrophus used carbon source of glucose and fatty acid source of acetic acid more than other sources of carbon Manuscript profile -
Open Access Article
640 - The effect of exosomes derived from bone marrow stem cells on the levels of estradiol and testosterone secreted from the ovarian granulosa cells of immature NMRI mice
Javad Baharara Sajad Farrokhyar akram eidi nasim HAYATIThe problem of infertility in the world today has become a social concern and can cause severe psychological trauma to couples. One of the most important ovarian cells are granulosa cells that affect the growth and maturation of oocytes. Exosomes are a special class of MoreThe problem of infertility in the world today has become a social concern and can cause severe psychological trauma to couples. One of the most important ovarian cells are granulosa cells that affect the growth and maturation of oocytes. Exosomes are a special class of extracellular vesicles that can trigger cellular responses by signaling to cells. The aim of this experimental study was to evaluate the secretion of estradiol and testosterone in granulosa cells treated with exosomes secreted from bone marrow stem cells. In this study, bone marrow stem cells were cultured and the culture medium of cells containing exosomes was collected. Subsequently, the presence and diameter of exosomes were examined using atomic force microscopy and electron microscopy. Finally, the concentration of hormones secreted from granulosa cells was assessed by ELISA method. The results obtained by atomic force microscopy and electron microscopy confirmed the presence of exosomes with an approximate diameter of 70 nm and also treatment of mice ovarian granulosa cells with exosomes derived from bone marrow mesenchymal stem cells increased the secretion of estradiol and testosterone by these cells. The results of this study confirm the effect of exosomes derived from bone marrow on the secretion of sex hormones and the effect on fertility Manuscript profile -
Open Access Article
641 - Study of the effect of oxidative stress on Nrf-2 cell signaling pathway in mesenchymal stem cells (MSCs)
parisa bostani elnaz khojaste changiz ahmadizadehThe study of mesenchymal stem cells showed that induction of autophagy in MSCs increased sensitivity to oxidative stress Maharatophagy induced resistance of MSCs to oxidative stress and increased survival of MSCs compared to control cells. The aim of this study was to i MoreThe study of mesenchymal stem cells showed that induction of autophagy in MSCs increased sensitivity to oxidative stress Maharatophagy induced resistance of MSCs to oxidative stress and increased survival of MSCs compared to control cells. The aim of this study was to investigate the effect of oxidative stress on the Nrf2 cell signaling pathway in mesenchymal stem cells. The present study was conducted at the Pharmaceutical Micro-Technology Research Center of Tabriz Medical Sciences in 2017. In this experimental study, mesenchymal stem cells were cultured in DMEM-F12 medium and after trypsinization, re-culture was performed and the fourth cell passage was selected. Then it was examined using MTT assay method. DNA extraction was performed from treated cells and DNA Ladder assay was performed. After cDNA preparation, the expression of Nrf2 genes in mesenchymal stem cells was measured by real-time PCR. Data analysis was performed using SPSS software. done. The results showed that oxidative stress could activate the Nrf2-Nngoi cell signaling pathway and that stem cells could inhibit stress through this pathway. Therefore, it is necessary to strengthen this pathway through dietary antioxidants and supplements to increase the effectiveness of cell therapy. Manuscript profile -
Open Access Article
642 - Evaluation of the hormonal treatments effect on biosynthesis of endol alkaloids in tissue culture, suspension culture and field culture
Ali. Kazemzadeh Haghighi. Sobhanian. Hamid.. Bakhshi Khaniki. Gholamreza.. Ebrahimi. Mohammad ali..The plant is a rich source of alkaloids that are distributed in all parts of the plant. The presence of valuable alkaloids in all parts of the plant has led to its introduction as a very important medicinal plant and its properties to be investigated. This study was con MoreThe plant is a rich source of alkaloids that are distributed in all parts of the plant. The presence of valuable alkaloids in all parts of the plant has led to its introduction as a very important medicinal plant and its properties to be investigated. This study was conducted to investigate the effect of growth regulatory treatments on the biosynthesis of indole alkaloids of Parvanesh medicinal plant in culture. Tissue, suspension culture and field culture were performed. The experiment was performed in three separate cultures, including tissue culture, suspension culture, field culture and the effect of simultaneous use of IAA and NAA growth regulators on the amount of alkaloids produced by the butterfly plant. . IAA hormones in three concentrations (0.1, 0.5 mg / L) and NAA (0.1, 0.5 0.5 mg / L) in three replications in a completely randomized field design Karaj Seed and Plant Breeding Research Institute was established in 1398. The experimental results showed that NAA increased the alkaloids of agemalicin, serpentine and increased the total alkaloids by about 20%. Among the growth regulators studied, IAA showed a decreasing effect on changes in alkaloid levels, and in some cases this decrease was about 10%. Also, the use of suspension culture method increased alkaloids and in field cultivation, the amount of total alkaloids increased compared to other methods. Based on the results of this experiment, it seems that the use of method In many cases, suspension cultivation has a relatively better advantage than the other two groups. Manuscript profile -
Open Access Article
643 - Effects of hydroalcoholic extract of Achilla millefolium and Salvia officinalis against human gastric Cancer cells
Omid Sofalian naser zare Saeed Latifi Sara Motalebinia Kobra HasanpourTreatment of cancer by medicinal plants has long been of interest to researchers. In the meantime, some plant species contain substances that, through apoptosis or necrosis, can inhibit or eliminate cancer cells. The family of mint and chicory are among the medicinal pl MoreTreatment of cancer by medicinal plants has long been of interest to researchers. In the meantime, some plant species contain substances that, through apoptosis or necrosis, can inhibit or eliminate cancer cells. The family of mint and chicory are among the medicinal plants that have many biological effects.The purpose of this study was to investigate the effect of Pennyroyal and Artemisia extract on gastric cancer cell line (AGS).In this study, aerial parts of plants were extracted. AGS cells were treated with the concentrations of Hydroatanolic extract (50-1000 g / ml) at 24, 48 and 72 hours intervals. Cell motility was estimated using MTT method and the rate of induction of apoptosis by flow cytometry with The Annexin-V .The results of MTT assay showed strong and dependent inhibitors of the concentration of cancer cell proliferation by various extracts of Achillea and Salvia. These extracts have a doseand time dependent anti cancer effect on AGS cells. In the study of apoptosis in treated cells, the extract of the Pennyroyal was more effective. Due to the cytotoxic effects of hydrotanolic extracts on AGS cells, these plants can be used as potential option for further studies on cancer treatment. Therefore, the purification of the active ingredient in these extracts and the determination of their effect mechanism is recommended. Manuscript profile -
Open Access Article
644 - Fabrication of electrospun silk fibroin scaffold and the effect of its pre-incubation in culture medium on survival and adhesion of rat bone marrow mesenchymal cells
Maryam Janitermi esmail fattahi Seyed Gholam Ali JorsaraiObjective: This study was performed to synthesize electrospun silk fibroin scaffold and to investigate the time-dependent effect of its pre-incubation in culture medium on the adhesion and proliferation of cells seeded on the scaffold. Methods: sericin was removed from MoreObjective: This study was performed to synthesize electrospun silk fibroin scaffold and to investigate the time-dependent effect of its pre-incubation in culture medium on the adhesion and proliferation of cells seeded on the scaffold. Methods: sericin was removed from silk cocoon and fibrin solution (3% w/v) was prepared using formic acid. Then, electrospun silk fibroin scaffold was made using lab-scale electrospinning machine and evaluated by scanning electron microscopy. Pre-incubation of scaffolds in culture medium was performed for 0, 1, 6, and 10 days and the hydrophilicity of scaffolds was evaluated by measuring the water contact angle. Rat bone marrow mesenchymal cells were then isolated, cultured, and seeded on scaffolds. After 21 days of cell seeding, cell viability (MTT method) and genomic DNA concentration of cells attached to the scaffold were evaluated. Results: The results showed that increasing the pre-incubation time in the culture medium decreased the water contact angle and increased the survival and proliferation of cells. In general, the present study showed that pre-incubation of electrospun fibroin scaffold with constant elasticity in culture medium leads to increased scaffold hydrophilicity and consequently increases the proliferation and survival of mesenchymal cells seeded on it. Conclusion: these findings can be used as an effective factor in seeding cartilage cell on scaffolds in tissue engineering. Manuscript profile -
Open Access Article
645 - Effect of irrigation regime on cotton golestan genotype (Gossypium hirsutum) yield, fiber quality and insilico analysis of CesA and XET1 genes involved in fiber quality
مریم kolahi elham faghani mina kazemian sedighe dodangi mohamad habibi omolbanin chekaniStudy of water stress effect in traits of crops is related to stress tolerance, increasing their growth and yield in stress situation.This research was performed to evaluate the impact of different irrigation regimes on cotton yield, fiber quality were conducted using a MoreStudy of water stress effect in traits of crops is related to stress tolerance, increasing their growth and yield in stress situation.This research was performed to evaluate the impact of different irrigation regimes on cotton yield, fiber quality were conducted using a split-plot factorial design with four irrigation levels (rainfed, 33%, 66% and 100%) as the main factor. After physiological maturation, fiber performance and quality traits were evaluated.protein and phylogenetic properties have been evaluated by bioinformatics tools. The results indicated that the highest yield with 1.2 kg was observed in 66% irrigation treatment. The highest fiber weight was observed in 66% treatment and the lowest in rainfed conditions. Seeds grown under 66% irrigation saved more water and produced potential seeds with high quality fibers. Bioinformatics analysis also revealed that the intracellular locations of CesA and XET1 enzymes are plasma membrane and cell wall, respectively. The enzymes CesA and XET1 belong to the protein family of transferases and hydrolase, respectively. Phylogenetic analysis revealed that the sequences of both cotton enzymes with co-family genera were separated in the Malvaceae . It appears that in order to grow cotton seeds with desirable fibers in low water conditions and in dry areas, it is better to use seeds that are irrigated under optimal irrigation conditions (66%). by cultivating cotton seeds with about one third of the water requirement in three years, in addition to reducing the amount of water requirement and irrigation water consumption, better yields can be achieved. Manuscript profile -
Open Access Article
646 - Comparative study and physiological indexation of extracellular polysaccharids in cell culture and cyanobacterial proliferation
rezvan karami borzabad Abolfazl Baghbani- AraniExtracellular Polysaccharides or Extracellular Polymeric Substances, EPS are polyester compounds that are produce in some cyanobacterial genera. In this study, physiological characteristics and extracellular polysaccharides have been investigated and compared in three d MoreExtracellular Polysaccharides or Extracellular Polymeric Substances, EPS are polyester compounds that are produce in some cyanobacterial genera. In this study, physiological characteristics and extracellular polysaccharides have been investigated and compared in three different cyanobacteria; a heterocystic bundled, a nonheterocystic bundled and single cell strain. The results of growth rates and growth curves of these three samples indicate that cyanobacterium unicellular Synechococcus sp. Compared to heterocystic bundled; Nostoc sp. and nonheterocystic bundled Phormidium sp. is growing more. Meanwhile, the polysaccharide measurements of these three samples show that the production of the polysaccharides of all three samples at the end of the growth phase reaches the maximum and that the strain of Phormidium sp. has the ability to produce the highest amount of polysaccharides, especially extracellular, whereas the nitrogenase activity of these strains was also consistent with their growth, so that the strain of Synechococcus sp. has the most nitrogenase activity and Nostoc sp. has a second rank in this regard, with a minor difference. In this way it is concluded that the strain of Phormidium sp. is a prime example that has the ability to produce polysaccharides, especially extracellular polymers, to a large extent scale, and can compete in different sectors with synthetic polymers such as xanthan. Manuscript profile -
Open Access Article
647 - Evaluation of sperm morphology by stereology method in patients with different varicocele grades
Narges ShoohaniZad Shabnam Movassaghi haniyeh Bayat shabnam AbdiIntroduction: Varicocele is one of the most common causes of male infertility in which testicular function and sperm production process are impaired. In this study, sperm parameters and sperm morphology were compared between patients with different varicocele grades.Met MoreIntroduction: Varicocele is one of the most common causes of male infertility in which testicular function and sperm production process are impaired. In this study, sperm parameters and sperm morphology were compared between patients with different varicocele grades.Methods: This study was performed on 55 patients with grade 1, 2 and 3 varicocele as well as 32 fertile individuals (candidates for embryo donation or sex determination) as a control group. After collecting semen from patients, sperm parameters (number, motility and morphology of sperm) and sperm viability in different semen samples were examined. Also, sperm morphology (head, neck and tail length) was evaluated in different groups by stereology technique. Results: Sperm parameters including sperm count, motility and morphology were significantly lower in varicocele patients in comparison to control group and also sperm motility, survival, sperm count in the third degree varicocele group were significantly lower than other groups. There was no significant difference in sperm head volume and midline length between grade 1, 2 and 3 varicocele groups, but tail length in grade 3 varicocele group was significantly shorter than the other groups.Discussion and Conclusion: Varicocele, in all its degrees, is associated with a decrease in morphology and sperm count. Also, our study shows that the degree of varicocele affects sperm motility, morphology and viability, and sperm tail length. Manuscript profile -
Open Access Article
648 - Evaluation of NKP46 gene expression in celiac disease patients on a gluten free diet
Maryam Khodapanah Mohammad Rostami-Nejad Mehrdad Hashemi Hamid Asadzadeh-AghdaeiAccording to the previous studies, natural cytotoxicity receptors including NKP46 can play an important role in strengthening and sustaining immune responses against viral infection, which may have a role in the progression of inflammation in celiac disease. Moreover, I MoreAccording to the previous studies, natural cytotoxicity receptors including NKP46 can play an important role in strengthening and sustaining immune responses against viral infection, which may have a role in the progression of inflammation in celiac disease. Moreover, Interleukin-15, which is one of the most important inflammatory cytokines in celiac disease pathogenesis, can also change the expression of this type of receptors that leads to atrophy of intestinal villi. The aim of this study was to evaluate the intestinal expression of NKP46 gene in patients with celiac disease on a gluten-free diet in comparison with healthy individuals. In this study, 20 small intestinal biopsy samples were collected from patients with celiac disease and 20 samples from healthy subjects. After RNA extraction and cDNA synthesis, gene-specific primer pairs were designed, PCR conducted and NKP46 gene expression was evaluated by real-time PCR method. 8 females (40%) and 12 males (60%) in the patient group and 7 females (35%) and 13 males (65%) in the control group were studied. NKP46 gene expression was not significantly different between celiac patients who were on a gluten-free diet and healthy individuals (Pvalue: 0.4). The lack of significant difference in the expression of this receptor between the patient and control groups can be due to the effects of gluten-free diet adherence. Additional studies are recommended to achieve a more complete expression profile of these receptors and possible mutations affecting their expression in treated and untreated celiac disease patients. Manuscript profile -
Open Access Article
649 - Developmental stages of the pollen grains in Ash tree (Fraxinus excelsiorL.)
Maryam SharifShoushtari Ahmad Majd Mostafa Moin Gholam Ali KardarFraxinus excelsior is a common tree belongs to the Oleaceae family which is commonly found in the vegetation of most areas of Iran, especially Tehran province. According to the reports of allergenicity of olive family and homology between genera and species of this genu MoreFraxinus excelsior is a common tree belongs to the Oleaceae family which is commonly found in the vegetation of most areas of Iran, especially Tehran province. According to the reports of allergenicity of olive family and homology between genera and species of this genus and high level of seasonal sensitivity to ash pollens, accurate knowledge of pollens is essential.In this research we investigated the pollen grains developmental characteristics of pure male flowers F. excelsior. The flowers and buds, in different developmental stages, were removed, fixed in FAA70, stored in 70% ethanol, and following dehydration and embedding in paraffin, the specimens were sliced by a rotary microtome. Staining was carried out with PAS and contrasted with Hematoxylin and prepared specimens were studied under a light microscope. Also, to be observed pollen structure was examined by SEM and FESEM electron microscopy.The results indicated that consist of two stamens and anthers were four pollen sacs and pollen tetrads types were tetragonal and cubic. Pollen grains, when shed had three colpes and Striped-mesh ornaments and/or be observed along with orbicules of different sizes on the surface. The pollen grains, in this plant, are spherical in polar view and fusiform in equatorial view; mature pollens are prolate, tricolporoidate with furrows disposed along polar axis. The disposition of the microspore in the tetrads is tetrahedral. The pollen grains are 2-celled when shed. Scrutiny cell and tissue of pollen grains can help in more thorough investigation on applications of aerobiology and identification of pollen allergens. Manuscript profile -
Open Access Article
650 - Inhibitory Effects of Small Molecule TPSF on Growth and Proliferative of Human Breast Cancer Cell Line MCF-7: A Laboratory Study
Kiavash Hoshmndi elham hoveizi SAAD GOORANI NEJAD mohammadreza TabandehBreast cancer among women cancers has been the first to suffer from mortality and morbidity. Today, small molecules are still dominating the field of drug innovation, because of their special properties. The aim of this study is the investigation of the growth inhibitor MoreBreast cancer among women cancers has been the first to suffer from mortality and morbidity. Today, small molecules are still dominating the field of drug innovation, because of their special properties. The aim of this study is the investigation of the growth inhibitory and anti-proliferation effects of TPSF (4-(4-Fluorophenyl)-4-oxobutyl]thio]-1,3,6,9-tetrahydro-1,3-dimethyl-6-thioxo-2H-purin-2-one) on MCF-7 breast cancer cell line. In this laboratory study, MCF-7 breast cancer cells were cultured in a medium containing serum 10% and the cells were treated with the concentrations of 0.5, 1, 2, 5, and 10 of TPSF in 1, 3, and 5 days. Then the inhibitory effects of TPSF on cell growth and proliferation were assessed by MTT assay. Molecular docking was performed using Molegro software. For data analysis, two-way ANOVA and Tukey's post hoc test were used. According to the results, TPSF significantly (P≤0.001) decreases the survival rate and proliferation of MCF-7 cells in a time and dose-dependent manner. So that, the cell viability of cells treated with concentrations of 0.5, 1, 2, 5, and 10 µM were 90, 79, 68, 50, and 90 % respectively after 24h that confirmed that cell viability significantly decreases (P≤0.001) depended on dose, and the concentration of 5 µM was determined as the IC50 concentration. The study of morphological showed changes consisting of cell shrinkage, nucleotide pigmentation, and fragmentation of chromatin. The docking results also confirmed the interaction of TPSF with HER2 and ER.TPSF inhibits the growth of breast cancer cells and can be regarded as an anticancer medicine. Manuscript profile -
Open Access Article
651 - Behavioral and electrophysiological study on bone marrow stromal cell transplantation with olive extract in repair of severed sciatic nerve in rats
MOSTAFA MOAZAMI GODARZI Nasim Hayati Roodbari Gholamreza Kaka Kazem ParivarBackground and purpose: Behavioral and electrophysiological study on the use of bone marrow stromal cell transplantation along with olive extract in the repair of severed sciatic nerve in rats.Materials and Methods: After sciatic nerve amputation, adult male rats were r MoreBackground and purpose: Behavioral and electrophysiological study on the use of bone marrow stromal cell transplantation along with olive extract in the repair of severed sciatic nerve in rats.Materials and Methods: After sciatic nerve amputation, adult male rats were randomly divided into 4 groups of 7.Healthy rats, rats with sciatica without treatment intervention, rats with bone marrow stromal cells treated with olive extract at the site of amputation, rats with bone marrow stromal cells injected at the site of injury.The rate of recovery was assessed by sensory motor activity of the sciatic nerve, electrophysiological studies.Results: Sciatic nerve motor evaluation, no control group returned to normal in the eighth week, cell therapy group was restored with olive extract in the eighth week. The level of AMP in the eighth week after the restoration of the cell therapy group with a gentle slope indicates the recovery process of the cell therapy group.Counting the number of nerve fibers at an area of 1000 μm, the number of nerve fibers in the cell therapy groups increased in the eighth week after repair, compared with the control group and the PLGA membrane group. By the end of the eighth week, the sciatic nerve index (Hot Plate test), the healing process of the cell therapy group with olive extract was more evident to other groups.Conclusion: bone marrow stromal cell transplantation repairs sciatic nerve and olive extract along with bone marrow stromal cell accelerates sciatic nerve repair. Manuscript profile -
Open Access Article
652 - Assessment of genetic diversity and phylogenetic relationship of some cultivated (Apium graveolens) and wild celery(Kelussia odoratissima) genotypes using SDS-PAGE
fatemeh Mahmoudi kurdi Ardeshir Joodmand sara ghaffarianThe study of proteins is an appreciate model for assessment genetic diversity and similarity between different genomes. Considering to the medicinal and nutritional importance of Apium graveolens and Kelussia odoratissima in this study genetic relationships and diversit MoreThe study of proteins is an appreciate model for assessment genetic diversity and similarity between different genomes. Considering to the medicinal and nutritional importance of Apium graveolens and Kelussia odoratissima in this study genetic relationships and diversity of 6 Kelussia genotypes based on seed proteins and 15 celery based on proteins of seeds and leaves 30, 45 and 60 days after germination were studied by SDS-PAGE. Presence and absence of the protein bands were scored as one and zero, respectively. The total number of bands, number of polymorphic bands, the percentage of polymorphic bands, number of private bands, number of alleles, number of effective alleles, genetic diversity, mean of heterozygosity, polymorphic information content and Nei gene diversity index were estimated. Also analysis of molecular variance, analysis of molecular variance to two first coordinates and grouping of populations based on minimum evolution algorithm and P-distance were done. Results showed high genetic diversity in both populations but higher heterozygosity and within population diversity in celery seed compare to Kelussia. Grouping of populations separated celery and Kelussia populations. Agreement of populations grouping with geographic dispersion was more strong in seeds than leaves Manuscript profile -
Open Access Article
653 - Using stem cells as a new approach for treatment of polycystic ovary syndrome
somayeh ebrahimi-barough fatemeh kouchakzadeh seyyed mahdi kalantar jafar Ai behrooz aflatoonianPolycystic ovary syndrome (PCOS) is a common disorder in women that usually occurs in reproductive age in a number of people around the world. Symptoms include impaired folliculogenesis, hyperandrogenism, menstrual irregularities, numerous small cystic follicles, infert MorePolycystic ovary syndrome (PCOS) is a common disorder in women that usually occurs in reproductive age in a number of people around the world. Symptoms include impaired folliculogenesis, hyperandrogenism, menstrual irregularities, numerous small cystic follicles, infertility, and chronic anovulation. The present review study was conducted with the aim of describing the use of stem cells for the treatment of PCOS, their biological characteristics and mechanism of action. The information related to this review study was collected from 53 papers that searched from databases such as SID, Magiran, PubMed, Google Scholar, Ironed Scopus and clinicaltrials. Currently, only the studies are at the level of pre-clinical studies on bone marrow mesenchymal stem cells, adipose stem cells, cord blood stem cells and exosomes derived mesenchymal stem cells, and there are only two studies on the Clinicaltrials.gov website as clinical studies. Due to the uncertainty of the safety of this method for the purpose of using stem cells in human, more studies in this field should be designed and implemented. Manuscript profile -
Open Access Article
654 - Experimental Study on Evaluation of Effects of Implantation Site of Mesenchymal Stem Cells/scaffold on Recovery of Diabetic in a Rat Model
elham hoveiziDiabetes Mellitus is an autoimmune and chronic disorder that has spread rapidly all over the world due to lifestyle and obesity. In this study, we are trying to find an effective step in controlling diabetes by designing an engineered tissue and grafting it to different MoreDiabetes Mellitus is an autoimmune and chronic disorder that has spread rapidly all over the world due to lifestyle and obesity. In this study, we are trying to find an effective step in controlling diabetes by designing an engineered tissue and grafting it to different sites in the animal model. Uterine endometrial mesenchymal stem cells (EnMSCs) were prepared using the enzymatic extraction method and PAN nanofiber scaffold by electrospinning method. EnMSCs were cultured on the scaffold and transplanted into diabetic rats treated with streptozotocin. The engineered tissue was transplanted in one group peritoneally in the abdominal cavity and the other group subcutaneously. Also, in another group of rats, EnMSCs were injected through the tail. After transplantation, blood glucose, insulin, and weight of rats were measured. The findings of the present study showed that the method and area of stem cell transplantation play an important role in the control of diabetes. In the groups receiving EnMSCs, glucose concentration, blood insulin level, and body weight were improved compared to the control group. Compared to other groups, glucose concentration decreased significantly and blood insulin level and body weight increased significantly in rats receiving a peritoneal transplant. In the subcutaneous transplant group and the injection group, there was no significant difference in the investigated criteria. According to the results of this study, transplantation of EnMSCs using PAN scaffold in the peritoneal site can be suggested for the treatment of diabetes, although more studies are needed in this field to provide a complete treatment. Manuscript profile -
Open Access Article
655 - Comparative investigation of cytotoxicity effects of iron oxide, zinc oxide and silver nanoparticles on white blood cells and leukemic cell line HPB-ALL in Vitro
Zahra Farahani Kazem Parivar nasim HAYATI Mona FarhadiTreatment with nanoparticles has attracted the attention of many researchers. Due to their small size and easy absorption, nanoparticles can be a suitable option for treatment. In this study, a comparative study of the anticancer effect of silver nanoparticles, zinc oxi MoreTreatment with nanoparticles has attracted the attention of many researchers. Due to their small size and easy absorption, nanoparticles can be a suitable option for treatment. In this study, a comparative study of the anticancer effect of silver nanoparticles, zinc oxide and iron oxide on leukemic cell line and white blood cells of HPB-ALL was done.Human white blood cells and leukemia cell line HPB-ALL were passaged. Iron oxide, zinc oxide and silver nanoparticles with different concentrations were added to the microplates containing the cells and the cells were treated with nanoparticles for 24 hours. PI was evaluated. The results obtained for leukemic cell line HPB-ALL and white blood cells were analyzed with the effect of three nanoparticles of silver, zinc oxide and iron oxide at a significant level (P<0.05). All three nanoparticles showed cytotoxic effects in both cell lines. The cytotoxicity effects of nanoparticles were higher in leukemic cell line HPB-ALL than in white blood cells. Among these nanoparticles, silver nanoparticles had a significant cytotoxic effect in HPB-ALL leukemic cell line compared to the other two nanoparticles. Evaluation of IC50, DNA damage and apoptosis induction in HPB-All leukemic cell line by silver nanoparticles was significantly higher than other two nanoparticles. According to the above results and further investigations of the penetration mechanism of each of the nanoparticles, it can be said that silver nanoparticles have the potential for therapeutic applications. Manuscript profile -
Open Access Article
656 - Anti-cancer effect of Artemisia turcomanica extract on breast cancer cell line (MCF-7)
zahra keshtmand Seyede narges naimi , Ardeshir HesampourThe prevalence of cancer and the side effects of treatment methods have provided a growing interest in the use of plants as a promising source of treatment.The use of medicinal plants in traditional medicine has been important for a long time and many of these medicinal MoreThe prevalence of cancer and the side effects of treatment methods have provided a growing interest in the use of plants as a promising source of treatment.The use of medicinal plants in traditional medicine has been important for a long time and many of these medicinal plants have antioxidant and anticancer effects. The purpose of this study is to investigate the anticancer effects of Artemisia turcomanica extract on breast cancer cell line (MCF-7)and its effect on Bcl2 and Bax gene expression.In this experimental study, the effect of the hydroalcoholic extract of Artemisia turcomanica on viability and expression of Bax and Bcl2 genes in MCF-7 breast cancer cells was examined.For this purpose,MCF-7breast cancer cells were cultured and treated with the hydroalcoholic extract of Artemisia turcomanica(with different concentrations)for 24,48 and72 hours.The effect of the extract on cell viability was evaluated by MTT method.Next,RNA extraction was performed and after cDNA synthesis,the expression level of Bax and Bcl2 genes was measured by Real-time PCR method.This research showed that with the increase in concentration and time,the viability of the cells decreased significantly compared to the control samples.Also, the results of real-time PCR showed that the expression of Bax and Bcl2 genes changed significantly compared to the control sample at 48 and72 hours.The results showed that the extract of Artemisia turcomanica has cytotoxic and apoptotic effects on the MCF-7 cell line, so that by conducting more studies, the extract of this plant can be used as an anti-cancer biological product in the treatment of cancer Manuscript profile -
Open Access Article
657 - Histological study of seed development in Tribulus terrestris L. (Zygophyllaceae)
fahimeh mokhtari elham mohajel kazemi mina kazemian mahboubeh aliasgharpour ali movafeghiThe study of embryonic and endosperm development in different plant species is important from a phylogenetic and systematic point of view. The aim of the present study was to investigate the histological evaluation of seed development in Tribulus terrestris L. by micros MoreThe study of embryonic and endosperm development in different plant species is important from a phylogenetic and systematic point of view. The aim of the present study was to investigate the histological evaluation of seed development in Tribulus terrestris L. by microscopic analysis. Samples were studied at different developmental stages after fixation by different histological techniques. The results showed that the ovules were anatropous, bilayer and axially placentation. Endosperm was observed in the early stages, which was a nuclear type that changed to a cell type during embryonic development. In the latest stages, remnants of the endosperm were observed as a net-like structure around the cotyledons. According to histological studies, divisions occurred faster in the basal cell than in the apical cell. The suspender was completely degenerated during the torpedo embryo stage. According to cyto-chemical studies, accumulation of starch grains in the seed coat was observed in the early stages of embryonic development. Moreover in the mature embryo, storage components contained protein bodies and lipid compounds. The seed coat consists of two layers, the outer layer of which contains calcium oxalate crystals. Fluorescent microscopic analysis showed that a cumulative lipid nature of waxes was observed in the grain. It seems that the study of features such as the pattern of organ formation in this plant can be effective in understanding the heterogeneity between species of the Zygophyllaceae family. Manuscript profile -
Open Access Article
658 - Differentiation of amniotic membrane mesenchymal stem cells (hAMSCs) cardiomyocyte on PGS-co-PCL / PGC / PPy / Gelatin scaffold and its effect in the treatment of myocardial ischemia in adult male Wistar rats
mahsa Ale Ebrahim NASTARAN BAHRAMI nooshin barikrow yasin asadi fateme roholah ali salimiAbstractIntroduction: The cardiac ischemia and its subsequent failures have a high prevalence and its treatment is dangerous, expensive and ineffective. With the implant of mesenchymal stem cells, researchers hope to replace the dead tissues and reactivate the damaged p MoreAbstractIntroduction: The cardiac ischemia and its subsequent failures have a high prevalence and its treatment is dangerous, expensive and ineffective. With the implant of mesenchymal stem cells, researchers hope to replace the dead tissues and reactivate the damaged parts of the heart. Materials and methods: After the differentiation of mesenchymal stem cells of the amniotic membrane into heart muscle cells, by closing the left anterior descending coronary artery (LAD) for 45 minutes, acute ischemia was induced in male Wistar rats. Then reperfusion was performed in male rats. Then treatment groups, including: differentiated stem cells, stem cells with PGS-co-PCL/PGC/PPy/Gelatin scaffold and scaffold group, were implanted into the damaged heart. After 2 and 4 weeks, echocardiography was performed and angiogenesis was examined in the heart tissue using the immunohistochemical technique.Results and discussion: In treatment groups with mesenchymal cells and scaffolds + mesenchymal cells compared to the control, the amount of cardiac ejection fraction (EF), ejection fraction (FS) and cardiac stroke volume (SV) increases. Also, by examining the growth of VEGF in different groups and the control group, there was a significant increase in the expression of this angiogenic factor in the group receiving the scaffold + mesenchymal cells compared to other groups, which seems to use the PGS-co-PCL/PGC/PPy./Gel scaffold has created enough and suitable space for growth of vessels in the myocardium. Manuscript profile -
Open Access Article
659 - Evaluation of the growth regulators, sugars and amino acid tryptophan effect on the rate of tryptophan decarboxylase enzyme on Catharanthus roseus (L.) G.Don. in tissue culture, cell suspension culture and field culture conditions
ali kazemzadeh haghighi hamid sobhanian gholamreza bakhshi khaniki mohamadali ebrahimiCatharanthus roseus The most important species from Apocyanaceae contains an important and special group of indole alkaloids with a great medicinal value, which are distributed in all organs of the plant. The presence of valuable alkaloids in all organs of the plant has MoreCatharanthus roseus The most important species from Apocyanaceae contains an important and special group of indole alkaloids with a great medicinal value, which are distributed in all organs of the plant. The presence of valuable alkaloids in all organs of the plant has led to the introduction of this species as very important medicinal plants and their properties to be studied. This study was performed to investigate the effect of growth regulatory treatments on the activity of tryptophan decarboxylase (TDC) which is a cytosolic enzyme and a key enzyme in the secondary metabolite biosynthesis The effects of some growth regulators such as KIN, BA, NAA and IAA in three concentrations (0.1, 0.5, 1.0 mg/L) as well as various sugar treatments like sucrose, fructose and glucose in 3 concentrations (2% , 4% , 6%) and also the amino acid tryptophan (at concentrations 100 and 200 mg/L, were investigated on TDC enzyme activity. The experimant was performed in three replications as a factorial in a completely randomized design in Karaj Seed and Plant Breeding Research Institute. in the applied IAA and NAA at concentrations of 0.1 and 0.5 mg/L respectively, increased the activity of TDC by about 10%. But cytokinins, KIN and BA at 1,0 mg/L had the greatest promotion effect of about 40%. Sugars such as Sucrose in concentrations 6%, fructose and glucose in 4% and amino acid tryptophan in concentration 100 mg/l had the maximal effects on the activity of TDC enzyme Manuscript profile -
Open Access Article
660 - Investigation of hydroalcoholic extract effect of Cordia Myxa fruit on the expression of BCL-2 and BAX genes in the apoptotic pathway and cell proliferation in human lung cancer cell line.
NAHID ASKARI Kian Aghaabbasi elham rezvannejadCancer is one of the most important causes of death worldwide. On the other hand, the therapeutic use of medicinal plants has increased during recent years. For this purpose, the aim of the present research was to investigate the effect of a Cordia myxa fruit extract on MoreCancer is one of the most important causes of death worldwide. On the other hand, the therapeutic use of medicinal plants has increased during recent years. For this purpose, the aim of the present research was to investigate the effect of a Cordia myxa fruit extract on cellular proliferation and apoptosis gene expression (BCL-2 and BAX) in lung cancer cell line (A549). The plant was collected and Hydroalcoholic extract was prepared by macerating method. Various concentrations of Cordia myxa extracts (of 0.25, 0.5, 1, 2, 4 mg/mL) obtained to treat lung cancer and fibroblast cell lines. Cells were examined by MTT-assay and Real Time RT-qPCR to determine the plant extract-induced cytotoxicity in cell lines with and without treatment The results showed that, the concentration of ≥2 mg/ml extract had a significant lethal effect on cancer cells. The expression of BAX gene in the treated cell line increased and the expression of BCL-2 gene decreased compared to the control. The extract of Cordia myxa fruit didn’t show toxicity effects when used in low concentrations. However, this extract demonstrated the lower cytotoxicity against normal fibroblast cells. The combination therapy can be less toxic if both (plant extract and chemotherapeutic agent) use to treat cancers. It can be useful with fewer side effects of chemotherapeutic agents. Manuscript profile -
Open Access Article
661 - A Comparison of Chicken-Derived Fibroblast Cells and Quail Cells Based on Proliferation and Viability Potential
elham hoveizi Ali AghaeiThe avian stem cells are an excellent in vitro model for development and pharmacology educations. These cells have the potential for self-renewal and differentiation and can be considered as a valuable technology in the poultry industry. The purpose of this study was th MoreThe avian stem cells are an excellent in vitro model for development and pharmacology educations. These cells have the potential for self-renewal and differentiation and can be considered as a valuable technology in the poultry industry. The purpose of this study was the derivation, culture, and comparison of chicken fibroblast cells to quail cells, regarding cell doubling time and the rate of cell viability during various cell passages. In this experimental study, fertilized eggs were obtained and fibroblasts were isolated with an enzymatic digestion method and of cultured in DMEM medium including 10% FBS for various passages. Population doubling time (PDT) and cell viability were evaluated by trypan blue staining and MTT assay. Data indicated that both cells had a maximum proliferation when cultured in a DMEM containing 10% FBS at 38 C˚. Based on our results, PDT was measured 16±2 h for both two cells during the first o third passages. But, the population of the chicken fibroblasts was doubled in number each 28±2 h, while this value was 36±2.1 h for quail cell population (p<0.05) during the third to sixth passages. Also, cell viability results were according to PDT results. This study demonstrated a potential of self-renewal and cell viability of quail fibroblast cells as a new avian cell source and suggested to use of these cells in future manufacturing applications. Manuscript profile -
Open Access Article
662 - A comparative study of the therapeutic effects of mesenchymal stem cells on polycystic ovary syndrome in various animal models
Umeh Leila Bakhshi Seyed Gholam Ali Jorsaraei Ramzan Khanbabaeia Maryam Gholamitabar tabari Seyedeh Zahra BabazadehInfertility is a global health problem. One of the main causes of infertility in women is polycystic ovary syndrome (PCOS). Different methods are used to treat such people. Using stem cells and its products can be a good alternative for its treatment. There are differen MoreInfertility is a global health problem. One of the main causes of infertility in women is polycystic ovary syndrome (PCOS). Different methods are used to treat such people. Using stem cells and its products can be a good alternative for its treatment. There are different models for inducing PCOS in animal models. Mesenchymal stem cells reduce ovarian dysfunction in PCOS mice. Tail injection of BM-MSC will improve the process of folliculogenesis. Intraovarian injection of BM-Hmsc and UC-MSC mesenchymal stem cells improves the process of folliculogenesis. AMSCs mesenchymal stem cell injection is associated with a positive result in fertility. MSC-EV stem cells improve fertility and increase folliculogenesis. One of the main causes of infertility in women is polycystic ovary syndrome (PCOS). The use of cell therapy for various diseases including PCOS is considered. The use of MSC in the treatment of infertility is in its preclinical research stages. The safety and efficacy of MSCs in the treatment of infertility needs further investigation. In this study, we have compared the therapeutic effects of mesenchymal stem cells on polycystic ovary syndrome in various animal models. Manuscript profile -
Open Access Article
663 - The consequences of selfability of human resources in governmental organizations in Iran
mohsen garekhani kumars Ahmadi adel salavatiControl-based approaches in management are becoming empowerment-based approaches that self-empowerment is the newest type of this approach. The aim of this study was to investigate the consequences of human resource self-empowerment in Iranian government agencies. In th MoreControl-based approaches in management are becoming empowerment-based approaches that self-empowerment is the newest type of this approach. The aim of this study was to investigate the consequences of human resource self-empowerment in Iranian government agencies. In this research, two documentary (library) and field methods were used to collect data, so that based on documentary method, the researcher obtained the information through vector jack by reviewing different texts. In order to use the field method, semi-structured interviews and questionnaires were used. The sample size was considered for the qualitative method of 40 individuals, among which 20 managers of governmental organizations who were familiar with the topics of self-empowerment and 20 experts and experts of the initial model were taken into account and in the quantitative method, using Cochran's formula, 72 people including employees of the Economic and Finance Affairs Department of Kurdistan province were selected by simple random sampling. The data collected in the field section, obtained from interviews, were analyzed using the research method of the foundation data and the data obtained from the questionnaire were analyzed using SPSS statistical software. Findings indicated that implications in two individual and organizational levels were identified as the consequences of self-capability phenomenon in Iranian government agencies; In this way, the 'job satisfaction' and 'human resource excellence' are among their individual consequences and 'transformation of the administrative system', 'reducing costs' and 'organizational excellence' are among organizational consequences. The results of measuring the implications of self-empowerment of resources in the formation of resources, with the confirmation of the findings, indicate that respondents have evaluated the status of the transformation of the administrative system (with an average of 3.18) and lower costs (with an average of 3.04) better than two other outcomes. Nevertheless, 31 percent of respondents have evaluated the status of the outcomes in the organization at a low level, 47% moderate and 23% high. Regarding the range of changes (5 1) and the mean obtained (2.91), respondents in general have evaluated the status of the implications in the middle-level organization. Manuscript profile -
Open Access Article
664 - The consequences of selfability of human resources in governmental organizations in Iran
Mohsen Gharakhani kumars Ahmadi adel salavatiControl-based approaches in management are becoming empowerment-based approaches that self-empowerment is the newest type of this approach. The aim of this study was to investigate the consequences of human resource self-empowerment in Iranian government agencies. In th MoreControl-based approaches in management are becoming empowerment-based approaches that self-empowerment is the newest type of this approach. The aim of this study was to investigate the consequences of human resource self-empowerment in Iranian government agencies. In this research, two documentary (library) and field methods were used to collect data, so that based on documentary method, the researcher obtained the information through vector jack by reviewing different texts. In order to use the field method, semi-structured interviews and questionnaires were used. The sample size was considered for the qualitative method of 40 individuals, among which 20 managers of governmental organizations who were familiar with the topics of self-empowerment and 20 experts and experts of the initial model were taken into account and in the quantitative method, using Cochran's formula, 72 people including employees of the Economic and Finance Affairs Department of Kurdistan province were selected by simple random sampling. The data collected in the field section, obtained from interviews, were analyzed using the research method of the foundation data and the data obtained from the questionnaire were analyzed using SPSS statistical software. Findings indicated that implications in two individual and organizational levels were identified as the consequences of self-capability phenomenon in Iranian government agencies; In this way, the 'job satisfaction' and 'human resource excellence' are among their individual consequences and 'transformation of the administrative system', 'reducing costs' and 'organizational excellence' are among organizational consequences. The results of measuring the implications of self-empowerment of resources in the formation of resources, with the confirmation of the findings, indicate that respondents have evaluated the status of the transformation of the administrative system (with an average of 3.18) and lower costs (with an average of 3.04) better than two other outcomes. Nevertheless, 31 percent of respondents have evaluated the status of the outcomes in the organization at a low level, 47% moderate and 23% high. Regarding the range of changes (5 1) and the mean obtained (2.91), respondents in general have evaluated the status of the implications in the middle-level organization. Manuscript profile -
Open Access Article
665 - Using human resources on the basis of competence with emphasis on the progressive views of Imam Ali (AS (
Tahereh Hasoumi Soghra Afkaneh Abbas Shakouri Sheldehi Sadaf AkhtariHuman resources is one of the most invaluable assets and assets that are the pillars of an organization and its development is one of the programs and concerns of any organization; identifying, attracting, employing and benefiting from human resources in all organizatio MoreHuman resources is one of the most invaluable assets and assets that are the pillars of an organization and its development is one of the programs and concerns of any organization; identifying, attracting, employing and benefiting from human resources in all organizations is complex. Is the most functional process that managers always strive to achieve with all available capacities; This research aims to understand the use of human resources based on competence, which has been done from the perspective of Imam Ali (AS), is applied and has been mixed with the type of research; The statistical population of this study included 30 education and university experts who were aware of the method, manners and managerial effects of Imam Ali (AS); The researcher-made research tool includes 63 indicators that by performing its validity and validity and through data analysis (T test) and the findings of this study showed that Imam Ali (AS) 's progressive views on the competencies of human resources in two categories of human values And the values of excellence can be an approach in the modern age for all organizations, including education and universities; An approach that highlights the issue of human beings and people more than ever in the local community and organization. Manuscript profile -
Open Access Article
666 - Explaining the Transformational Leadership Model and Renewable Management with an Interpretive Futurology Approach to Iranian Culture and Mysticism
Rahnama Farid Davood Kia Kojouri Mohammad Javad Taghi Pourian Saeed IslamiOrganizational leadership is one of the most important and diverse topics in the field of organization and management. In the future, metaphorical argumentative research is not intended to predict but to gain insight. A new look at the phenomenon of the organization, an MoreOrganizational leadership is one of the most important and diverse topics in the field of organization and management. In the future, metaphorical argumentative research is not intended to predict but to gain insight. A new look at the phenomenon of the organization, an appropriate action and new horizons for its leadership and management is manifested. This research is based on a qualitative-quantitative method with a descriptive-analytical approach that seeks rich and important themes and concepts such as "Nowruz And "Farshkard", which originate from the culture of ancient Iran, should be used in metaphorizing the concepts of transformational leadership and renewed management. To revive and revitalize. Therefore, the metaphor of spring transformational leadership and renewable management based on the Iranian themes of "Nowruz", "Pomegranate and Phoenix" and "Farshkard" can be used based on Iranian themes and a native pattern can be used. Manuscript profile -
Open Access Article
667 - Microwave-assisted synthesis of nickel-copper nanocomposite for methanol electrocatalytic oxidation. An efficient anode material for alcohol fuel cell applications
محمد علی کامیابی Babak JalilianIn this study, the synthesis and application of bimetallic nickel-copper nanocomposites and reduction of graphene oxide simultaneously using microwaves are reported. The proposed synthesis method is a simple, fast and controllable process. The electrochemical behavior o MoreIn this study, the synthesis and application of bimetallic nickel-copper nanocomposites and reduction of graphene oxide simultaneously using microwaves are reported. The proposed synthesis method is a simple, fast and controllable process. The electrochemical behavior of the synthesized catalyst was investigated for methanol oxidation reaction (MOR) in alkaline medium. The effect of melamine on the electrocatalytic activity of the synthesized catalyst was studied by cyclic voltammetry (CV), chronoamperometry (CA) and electrochemical impedance spectroscopy (EIS) methods. Also, investigating the effect of melamine as a source of nitrogen leading to nitrogen doping in the reduced graphene oxide network showed that it partially leads to the formation of NiCu-N structures. And this metal-N bond increases the catalytic activity towards MOR. The promoting effect of melamine was proved by an increase of 203 μA in the current and a decrease of 20 mV in the onset potential compared to other synthesized control catalysts during MOR activity. The results indicate the excellent performance of the synthesized catalyst as an anode in a direct methanol fuel cell. Manuscript profile -
Open Access Article
668 - Synthesis of copper magnetic nanocomposite based on nanofibrillated cellulose and investigation of its catalytic performance in reduction of dyes
Fatemeh Aliramezani Hannaneh HeidariIn this study, nanofibrillated cellulose (NFC) was used as a green and biodegradable material for the synthesis of copper magnetic nanocomposites without the addition of an external reducing agent or toxic solvents. Initially, nanofibrillated cellulose was magnetized fo MoreIn this study, nanofibrillated cellulose (NFC) was used as a green and biodegradable material for the synthesis of copper magnetic nanocomposites without the addition of an external reducing agent or toxic solvents. Initially, nanofibrillated cellulose was magnetized for easy separation using iron chlorides in ammonia medium, then used as a substrate and reducing agent for the formation of copper nanoparticles. The structure of the nanocomposite was characterized by various spectroscopic techniques including X‐ray diffraction (XRD), field emission scanning electron microscopy (FE-SEM), Fourier transforms infrared spectroscopy (FT-IR), Energy dispersive spectroscopy (EDS), and Inductively coupled plasma atomic emission spectroscopy (ICP-OES). The effect of nanocomposite drying methods such as freeze-drying and ambient temperature on catalytic activity was also studied. The results showed that the recyclable magnetic nanocatalyst Fe3O4@NFC/Cu in comparison with other reported catalysts had significant catalytic activity in degradation of three organic dyes (methyl orange, methylene blue, and 4-nitrophenol) with rate constants of 35.1×10-2 s-1 1.48×10-2 s-1 and 5.41×10-2 s-1, respectively. Also, this catalyst was recovered and used 4 times without significant loss of activity. Manuscript profile -
Open Access Article
669 - Evaluation of the influence of using reduced graphene oxide (RGO) on improvement of Cu-MOF performance as electrocatalyst for oxygen reduction reaction in fuel cells
mehdi mehrpouya seyed ali mousaviThe main target of this investigation is to synthesis and introduce several non-metallic electro catalysts with desirable performance and suitable price, for oxygen reduction reaction at cathode side. For this purpose, five electrocatalysts including graphene oxide (GO) MoreThe main target of this investigation is to synthesis and introduce several non-metallic electro catalysts with desirable performance and suitable price, for oxygen reduction reaction at cathode side. For this purpose, five electrocatalysts including graphene oxide (GO), nitrogen and sulfur doped graphene oxide (NS-RGO), copper metal organic framework (Cu-MOF), 6% GO-Cu-MOF, and 8% NS-RGO-Cu-MOF are synthesized by hydrothermal method. In continue, in order to investigate the structure, activity, and performance of synthesized electro catalysts, physical and electrochemical tests are employed, and obtained results are compared to the commercial 20% Pt/C. According to the physical tests outcomes, the structure of the synthesized electrocatalysts is uniform, and the layering is correctly performed. As well as, it was found that the size of electrocatalysts is in the range of nanometer. Based on the electrochemical tests, amongst the synthesized electrocatalysts, 8% NS-RGO-Cu-MOF has the best chemical activity. The onset potential of this catalyst is obtained by -0.06 V vs Ag/AgCl. Also, the peak associated with oxygen reduction reaction is shown in -0.08 V, which the current density in this voltage is -4.8 mA/cm2. Besides, the electron transferred number (n) for 8% NS - RGO - Cu- MOF is computed with the value of 3.53, which it indicates the reaction occurred near to the 4 electron pathway. The onset potential of 6% GO-Cu-MOF is gained by -0.11 V vs Ag/AgCl. Manuscript profile -
Open Access Article
670 - Improving the Performance of N719 Based Dye-Sensitized Solar Cell by Application of Polypyrrole/Polyaniline Conductive Polymers as a Counter Electrode
Mahsa Mahdavinia Gholamreza Kiani Ayub Karimzad GhavidelThe aim of this research is the fabrication of a titanium dioxide nanostructure-based solar cell sensitized with N719 dye, and improving its efficiency with the application of a core-shell structure of polypyrrole/polyaniline as a counter electrode. The solar cells with MoreThe aim of this research is the fabrication of a titanium dioxide nanostructure-based solar cell sensitized with N719 dye, and improving its efficiency with the application of a core-shell structure of polypyrrole/polyaniline as a counter electrode. The solar cells with polymeric counter electrode were fabricated, in variable thicknesses by two spin coating and drop coating methods, and evaluated. In addition, the effect of nanowires and titanium dioxide nanoparticles concentration, present in photo-anode, was investigated on the performance of solar cell. The absorption amount of N719 dye was studied by spectrophotometer, and the maximum absorption was obtained at the wavelengths of 380 and 530 nm. The structural investigation of photo-anode and counter electrode by scanning electron microscope showed that the combination of nanoparticles and titanium dioxide nanowires with 1:9 ratio leads to a porous structure with a high surface-to-volume ratio that has a significant effect on the absorption of the dye and solar cell efficiency. The prepared solar cell by the drop coating method did not have appropriate performance. So, the focus of the research was directed towards the sample prepared by spin coating method. The solar cell sample with the counter electrode, containing polypyrrole/polyaniline, fabricated by spin coating method offers the open circuit voltage of 0.71 V, short circuit current of 2.58 mA, fill factor of 57.38, and efficiency of 1.05, which open circuit voltage and fill factor have been improved by 7.6 and 35 times compared to similar samples, respectively. Manuscript profile -
Open Access Article
671 - A comprehensive review of corrosion prevention methods for perovskite solar cells
Majid Mirzaee Tayyebeh Mohebbi Alimorad rashidiIn recent years, perovskite solar cells (PSCs) have been considered one of the most promising photovoltaic technologies due to their affordability and excellent performance. However, perovskites are sensitive to parameters such as humidity, oxygen, temperature, and elec MoreIn recent years, perovskite solar cells (PSCs) have been considered one of the most promising photovoltaic technologies due to their affordability and excellent performance. However, perovskites are sensitive to parameters such as humidity, oxygen, temperature, and electrical bias. Changes in the composition and structure of materials from the precursor to the resulting perovskite lead to various defects. During long-term operation, these defects often act as the initiation of degradation to deteriorate PSC performance. A series of methods have been developed to prevent contact between the corrosive environment and perovskite. For this purpose, various techniques have been designed to control these parameters, which include removing corrosion sites during construction, eliminating corrosion sites during machine operation, and preventing contact between the corrosive environment and perovskite. In this review, the lifetime of PSC is discussed from the point of view of corrosion science. Finally, the use of a series of anti-corrosion strategies (passivation, surface coating, machining) in corrosion science significantly increases the stability of perovskite cells. Manuscript profile -
Open Access Article
672 - Evaluation of methylcellulose role in thermosensitive hydrogel structure as injectable system for tissue engineering application: fabrication and characterization
Sogol Motalebi Tala Tapeh Mazyar Sharifzadeh Baei Saeed Heydari KeshelOne of the challenges in tissue engineering is polymer material selection and design of a suitable structure for hydrogels. In this study, N-isopropylacrylamide/Acrylic acid/N-Acryloxysuccinicimide/2-Hydroxyethyl methacrylate-poly lactide hydrogel (NIPAAm/AAC/NAS/ MoreOne of the challenges in tissue engineering is polymer material selection and design of a suitable structure for hydrogels. In this study, N-isopropylacrylamide/Acrylic acid/N-Acryloxysuccinicimide/2-Hydroxyethyl methacrylate-poly lactide hydrogel (NIPAAm/AAC/NAS/HEMAPLA) was prepared with various molar ratio by ring-opening polymerization method to fabricate hydrogel substrate with properties of injectability, thermosensitive, physical and mechanical similar of soft tissues. The hydrogel with the ratio of 80/5/5/10 was selected as ideal groups (group 1). Methylcellulose was also used in the hydrogel structure to improve quality of the hydrogel (group 4). Then, the physicochemical, mechanical and biological properties of the hydrogels were evaluated. The results showed, molar ratio of polymers not only plays an important role in enhancing hydrophilicity, porosity, elastic modulus-like soft tissues, and cell proliferation, but also the presence of methyl cellulose lead to the improvement of the mentioned properties. So that, hydrogels of groups 1 and 4 provide an ideal environment for improving cellular activities due to hydrophilicity of more than 51%, elastic modulus-like cardiac tissues (68.1 kPa and 79.22 kPa, respectively), biocompatibility above 90%, with compared to other groups. It seems that the mentioned hydrogels (1 and 4 groups) can imitate soft tissue properties such as cardiac and be effective to regenerate and repair. In the other hand, these thermosensitive and inject ability hydrogels lead to a uniform mixing of cells and growth factors, as well as can apply to the cell therapy of soft tissue. Manuscript profile -
Open Access Article
673 - Evaluation of photovoltaic properties of polymeric solar cell comprising quantum dots with perovskite ligands
رضوان سلطانی علی اصغر کتبابin the present study, attempts have been made for the first time to investigate the influence of lead sulfide (PbS) colloidal quantum dots along with their ligand exchange from long-chain insulating oleic acid )OA) to the short-chain semiconducting methylammonium lead i Morein the present study, attempts have been made for the first time to investigate the influence of lead sulfide (PbS) colloidal quantum dots along with their ligand exchange from long-chain insulating oleic acid )OA) to the short-chain semiconducting methylammonium lead iodide )MA4PbI6), called perovskite, upon the photon harvesting efficiency and photovoltaic characteristics of bulk heterojunction (BHJ) polymeric solar cell comprising ternary photo active layer based on poly )3-hexyl thiophene))rrP3HT) as electron donor and PC61BM as acceptor. According to the photo absorption spectrum obtained within UV-Vis and NIR regions, the ternary cells based on OA and MA4PbI6 capped PbS exhibit enhanced photon harvesting efficiency compared with their binary counterpart cell. The steady state photoluminescence results reveal efficient electron transfer from photoexcited P3HT to QDs and hole transfer from photoexcited QDs to P3HT, leading to the improved power conversion efficiency (PCE) of the ternary cells. However, compared with OA, the semiconducting perovskite )MA4PbI6) ligand shows to be much more effective in increasing power conversion efficiency, so that 6% improvement in PCE is seen by the introduction of 6% PbS QD capped with perovskite ligand unlike PbS QD with OA ligand which had adverse effect on the photovoltaic properties of p 3HT: PC61BM solar cell. This is explained to be due to the insulating characteristic of long chain OA as well as improved charge carrier transport in the case of PbS capped perovskite based ternary solar cells. Manuscript profile -
Open Access Article
674 - Design of a drug intelligent carrier based on carboxymethyl cellulose-acrylamide as a closed loop system in drug delivery and kinetic study of insulin release
لیلا ذوالقدر بهمن واشقانی فراهانی حسین قاسم زادهThe present investigation was aimed to develop an intelligent closed-loop insulin delivery system based on carboxymethyl cellulose-g-polyacrylamide )CMC-g-PAAm( hydro gel. To control the release of insulin in response to the concentration of glucose, glucose oxidase )GO MoreThe present investigation was aimed to develop an intelligent closed-loop insulin delivery system based on carboxymethyl cellulose-g-polyacrylamide )CMC-g-PAAm( hydro gel. To control the release of insulin in response to the concentration of glucose, glucose oxidase )GOx( was immobilized in the hydro gel. The hydro gels were prepared by polymerization of AAm in the presence of CMC via a free radical polymerization method. Fourier-transform infrared spectroscopy )FTIR(, thermo gravimetric analysis )TGA/DTG(, and scanning electron microscope )SEM( were used to characterize the structure of the insulin loaded hydro gels. The sensitivity of the intelligent drug carrier to glucose concentration was investigated by UV-Vis Spectroscopy at 280nm.Optimization of the hydro gels loading characteristics was studied by full factorial design. Finally, insulin release from the synthesized drug delivery system was investigated by various kinetic models Manuscript profile -
Open Access Article
675 - Manganese polymeric sensor based on scanometry
فائزه کائدی شیدا اسمعیلزاده عبدالرضا خواجهزادهIn this study, a new and inexpensive polymeric sensor was developed for determination of Manganese in the aqueous media. The scanometric method was used to measure the color intensities of each polymeric film. In the scanometry, the image of films were transferred into MoreIn this study, a new and inexpensive polymeric sensor was developed for determination of Manganese in the aqueous media. The scanometric method was used to measure the color intensities of each polymeric film. In the scanometry, the image of films were transferred into image analyzing software. In the software any spots of the film were analyzed to red, green, and blue color parameters. For the preparation of polymeric manganese sensor film, triacetylcellulose was chosen as substrate and by using the activation process, Brilliant Cresyl Blue stabilized on inexpensive polymer substrate. After the polymer film made quite active, the experimental parameters including film response time, range of pH, concentration of brilliant cresyl blue was optimized. In this study, linear range and sensitivity of polymeric sensor film for all color parameters were obtained. Maximum linear range was obtained for red and blue (equal) and minimum linear range was obtained for green paremeter. Also, the green parameter had maximum sensitivity in the films. Manuscript profile -
Open Access Article
676 - Evaluation on cross-linked nano microbial cellulose properties as bone scaffold
نیلوفر ادیب عشق ابوسعید رشیدی امین مفتاحی -
Open Access Article
677 - Modification of Bacterial Cellulose Rehydration via Cross-linking with Succinic Acid
امین مفتاحی مهشاد سعادت کاشف صابری سمیه علی بخشی -
Open Access Article
678 - Fire in Iranian and Vietnamese Mythology: A Comparative Study
Elhām Rastād Nāsser Nikoubakht phuong Vo Ti Thanh Fire is one of the most important and mysterious elements of the universe, and it can be said that the human civilization began with its discovery. The myths from different ethnic groups show how man discovered fire and what its significance and status was. The im More Fire is one of the most important and mysterious elements of the universe, and it can be said that the human civilization began with its discovery. The myths from different ethnic groups show how man discovered fire and what its significance and status was. The important place of fire in the myths of Iran and Vietnam and the similarity of some rituals of the two countries in which fire is sanctified and worshiped, show that there are common cultural aspects between the two nations. The purpose of this study is to better understand the myths of Iran and Vietnam, especially the myths related to fire. Using the descriptive-comparative method, in the present article, an attempt has been made to study some myths of the two countries and the narratives related to the element of fire. According to the classification of myths related to gods and rituals and the discovery of fire, the results of the study show cultural similarities between the two countries, as Fire Dancing Festival in Vietnam is similar to the Chaharshanbe Suri and the Azargan festival in Iran. Also, in the myths of the two countries, fire symbolizes victory over the enemy and hell symbolizes the punishment of sinners. The difference between the mythological narratives of Iran and Vietnam is more about the gods and how to discover fire. Manuscript profile -
Open Access Article
679 - Empirical Evidence for Text and Reader Interaction in Fourth Grade Accelerated Students: Is Reading Literacy a Criterion for Academic Acceleration
Hamidreza Hassanabadi Ebrahim Talaei Azadeh Seyed Mirzaei Jahaghi Goalrokh Bararpourthe most important learning needs of students are reading and reading comprehension skills and it is expected that accelerated and gifted students will have an acceptable performance in these skills. In this study, reading comprehension of 3 participants group evaluated Morethe most important learning needs of students are reading and reading comprehension skills and it is expected that accelerated and gifted students will have an acceptable performance in these skills. In this study, reading comprehension of 3 participants group evaluated that including: 1) accelerated students (N=128, females 53 and males 75), 2) non-accelerated students with the same age but in different grade (N=122, females 50 and males 72) and 3) non-accelerated students in the same grade but different age (N=114, females 47 and males 67).participants were matched based on their general intelligence, gender, educational level and occupation of the parents and the social-economic status. Reading comprehension was assessed in two informational and literary domains by two stories, the Ant and the Giraffes, from the International Study on PIRLS Literacy (2001, 2006). The data were analyzed using a mixed-design analysis of variance model. The results indicated that reading and reading comprehension performances were not significantly different between the three groups. There was no sex difference in reading and reading comprehension performances. The implications of the findings for educational policymakers, planners, and users were discussed. Manuscript profile -
Open Access Article
680 - Perceived Childhood Attachment Patterns and Personality Characteristics in Cell phone dependency
Mehdi Keyvankar Majid Pakdaman fatemeh Shahabizadehthis study examined the relation of perceived childhood attachment and personality characteristics with cell phone dependency in high school students. Three hundred and thirty students (205 girls, 125 boys) were selected by multistage cluster sampling method from third Morethis study examined the relation of perceived childhood attachment and personality characteristics with cell phone dependency in high school students. Three hundred and thirty students (205 girls, 125 boys) were selected by multistage cluster sampling method from third and fourth junior high schools of Birjand city and answered Childhood Attachment to Each Parent Scale (Hazan & Shaver, 1986), Cell Phone Dependency Questionnaire (Jafarzade, 2010) and NEO-Personality Characteristics Inventory-Short form (Costa & McCrae, 1992). Path analysis method was used for data analysis. Findings Showed significant relationship between secure attachment styles to parents and personality characteristics (except extroversion and openness) with cell phone dependency in high school students. Furthermore, one's maternal insecure attachment style and neuroticism were predictive of students' vulnerability to cell phone dependency Manuscript profile -
Open Access Article
681 - The effect of walnut''s green skin on coloration of Oscar fish (Astronotus ocellatus)
M. Abbasi Oghda A. Vosooghi A. MatinfarThe effect of oral green skin of walnuts on the coloration of Oscar fish (Astronotus ocellatus) was studied. Albino Oscar fish with an average weight of 60 grams 5/01 ± 0/18 and 54/84 ± 2/23 mm average length in the form of 3 experimental and one control and each with t MoreThe effect of oral green skin of walnuts on the coloration of Oscar fish (Astronotus ocellatus) was studied. Albino Oscar fish with an average weight of 60 grams 5/01 ± 0/18 and 54/84 ± 2/23 mm average length in the form of 3 experimental and one control and each with three repetitions were divided. Twelve aquariums with dimensions of 50 × 40 × 33 cm was used. Control was fed with no food additives (food stand). For the first treatment food containing 0.1 percent walnut hull was used, 0.2 percent was used for the second treatment with the diet and in the third treatment fish were fed with food containing 0.3 percent walnut hull. The breeding period lasted 8 weeks (56 days). Every 20 days biometrics (Biometry) was carried out. Average water temperature in the aquarium during the study period was 28.07 ± 1.09 °C, with an average of 5.38 ± 0.15 milligrams per liter of dissolved oxygen, average pH was measured to be 8.03 ± 0.33 and average TDS, 33.27 ± 1.32 mg. After the breeding period, 3 fish from each treatment were randomly selected to assess the rate of change of color obtained using L* a* b* colorimetric system using a CHROMA METER CR-40. Colorimetric analysis of fish skin from treatments showed that oral administration of green walnut caused significant skin discoloration. Component b* representing the yellow color, was positive in the treatment 1, showed significant differencecompared to control (P0/05). The results showed that using the green skin of walnuts in the diet can increase the Oscar fish skin color towards yellow. It was shown that the level of 0.1 percent green skin of walnuts in the diet was the best level for increasing the yellow color in fish were detected. Manuscript profile -
Open Access Article
682 - Effect of cobalt as blood factors on Oscar fish (Astronatus ocellatus)
H. Emadi A. Mahani B. MokhayerFive groups of royal oscar (Astronatus ocellatus) with mean weight of 0.8±0.02 grams were fed for 90 days in 15 aquariums (30 30 40 cm). Their diet contained different levels of cobalt chloride with concentrations of 2.5, 3, 3.5 and 4 milligrams per kilogram of f MoreFive groups of royal oscar (Astronatus ocellatus) with mean weight of 0.8±0.02 grams were fed for 90 days in 15 aquariums (30 30 40 cm). Their diet contained different levels of cobalt chloride with concentrations of 2.5, 3, 3.5 and 4 milligrams per kilogram of feed. Three replicates were used for each concentration. During the experiment, blood factors including RBC, WBC, glucose and hemoglobin, in different groups were measured and compared with control diet. Results indicated that addition of cobalt as growth promotant, significantly affected RBC no., amount of glucose and hemoglobin in blood in all groups of species comparing those fed with the control diet, having no extra cobalt chloride (P<0.05). The best growth, RBC (0.82+1.69) 106 /mm3, glucose (5.03±129.66 mg/dl) and hemoglobin (1.66±8.01)g/dl were obtained with food 4 milligrams /kgr of cobalt chloride, and the highest WBC (9.0)103 /mL was obtained in diet with 3.5 milligrams/kgr of cobalt chloride. It is concluded that the species fed with most cobalt perforemed better than other fishes considering blood indices. Manuscript profile -
Open Access Article
683 - The effect of walnut’s green skin on growth of Oscar fish (Astronotus ocellatus)
M. Abbasi Oghda A. Vosooghi A. MatinfarIn this study, the effect of oral green skin of walnuts on the coloration of Oscar fish (Astronotus ocellatus) was studied. Sixty albino Oscar fish with an average weight of 5/01 ± 0/18 g and 54/84 ± 2/23 mm average length were divided in into three MoreIn this study, the effect of oral green skin of walnuts on the coloration of Oscar fish (Astronotus ocellatus) was studied. Sixty albino Oscar fish with an average weight of 5/01 ± 0/18 g and 54/84 ± 2/23 mm average length were divided in into three test experiments and one control and each with three repetitions. Twelve aquariums in the dimensions of 50 × 40 × 33 cm were used. The control was fed with a diet containing no food additives. The fish in treatment number one were fed with food containing %0.1 walnut hulls, the second treatment contained %0.2 walnut hulls in the fish diet and the third treatment was fed with food containing % 0.3 walnut hulls. The breeding period lasted eight weeks (56 days). Every 20 days biometrics (Biometry) were performed which included gravimetric analysis using a digital scale with 0.01g precision and a ruler with an accuracy of 0.1 cm for length analysis. Average water temperature in the aquarium during the study period was 28/07 ± 1/09 ° C. An average of 5/38 ± 0/15 milligrams per liter of dissolved oxygen, average pH of 8/03 ± 0/33 and an average TDS of 33/27 ± 1/32 mg was measured. At the end of the period of investigation, results showed that in terms of growth, the control with an average weight of 17/06 ± 1/21 grams and weight gain of 22/15 ± 1/08 grams had significantly (P<0/05) the highest growth rate compared with the other treatments. The third treatment with an average weight of 6/95 ± 0/56 grams and weight gain of 2/12 ± 0/64 grams showed the lowest growth rates. The control treatment also showed increased body weight and had the highest average of 337/01 ± 38/62 percent and was significantly different (P<0/05) from the other treatments. Treatment no. 3 with an average of 44/60 ± 15/48 percent had the lowest percentage of weight gain. Treatment no. 2 with an average of 95 percent have the highest rateof survival and was significantly different (P<0/05) from treatment no. 1, but was not significantly different (P≥0/05) compared to other treatments. Treatment no. 1 with an average survival of 55 percent had the lowest survival rate.The results showed that using the green skin of walnuts in the diet can reduce the growth factors in Oscar fish. However, 0.3 percent green skin of walnuts in the diet was most effective in slowing the fish growth rate. Manuscript profile -
Open Access Article
684 - Effect of Aloe vera extracts on the Growth, Feed Conversion Ratio of Oscar fish (Astronatus ocellatus)
M. A. Saeedi A. Matinfar B. SalimiNutritional needs are important in successful breeding process of the fishes. Aloe vera gel having beneficial compounds such as the eight essential amino acids, monosaccharides and polysaccharides, vitamins C, B12, B6, B2, B1, A, E and minerals, can be used as a valuabl MoreNutritional needs are important in successful breeding process of the fishes. Aloe vera gel having beneficial compounds such as the eight essential amino acids, monosaccharides and polysaccharides, vitamins C, B12, B6, B2, B1, A, E and minerals, can be used as a valuable supplement and food rations used in natural aquatic environment. Effect of prescription of this crude extract of plant Aloe vera in Oscar (Astronotus ocellatus) with an average weight of 17.57 ±2.56 g were studied in this research. Therefore, 54 fish in three treatments, each with 3 repeats were used in this research. Two treatments included a concentration of 2 and 5% crude extract of Aloe vera plant which were added to the Biomar feed size of 0.8 mm used for Carnivore fishes. Samples were fed for 60 days with the fortified feed. The control sample feed were not fortified. The results indicated that feed fortification with plant extracts of Aloe vera makes a significant difference (p<0.05) in weight gain, growth factor and coefficient of obesity and reduced food conversion factor compared with controls, and increase in fortification showed an increased effect. No mortality was observed in both treatments. Fortified feed at 5% showed a better result as a whole. Manuscript profile -
Open Access Article
685 - Study of effect of NAO Index on temperature and precipitation of southern coastal region of Caspian Sea in 1977-2009 periods
S. Tabarestani A. AsgariThe North Atlantic oscillation (NAO) is one of the effective indices in changing atmospheric situation of northern hemisphere .Southern coastal region of Caspian Sea is affected by different atmospheric systems and teleconnections such as NAO because of its special geog MoreThe North Atlantic oscillation (NAO) is one of the effective indices in changing atmospheric situation of northern hemisphere .Southern coastal region of Caspian Sea is affected by different atmospheric systems and teleconnections such as NAO because of its special geographical situation. In this research, precipitation and temperature data of southern coastal region of Caspian Sea are examined for 8 synoptic stations in 1977-2009 period. NAO index data are also received from cpc.noaa.gov website. Precipitation and temperature data were examined with their corresponding NAO indices data by correlation test in monthly and yearly time scales. Furthermore, we found that in this region, when NAO index increases, precipitation will increase and temperature will decrease and vice versa. During recent years, NAO index shows negative trend, so we expect decrease of precipitation and increase of temperature in the region. Manuscript profile -
Open Access Article
686 - Effect of Cu 2+ on cell number and chlorophyll a content of green alga Scenedesmus obliquus
H. Keyhanian F. Rafiee K. Mehdinejad E. ShirvaniAquatic environments are often exposed to heavy metals, this can affect aquatic organisms. The effect of Cu 2+ on cell density and chla content of S.obliquus was studied. The algae were grown for 5 days at temperature of 2± 23 ˚c and light intensity o MoreAquatic environments are often exposed to heavy metals, this can affect aquatic organisms. The effect of Cu 2+ on cell density and chla content of S.obliquus was studied. The algae were grown for 5 days at temperature of 2± 23 ˚c and light intensity of 300 lux on z8 medium .Copper treatment was carried out at a concentration of 0 (control) ,2,4,,6 and 8 mgl-1. Cell counting was performed at 0,24,48,72 and 96 hours using heamocytometer and amount of chla was determined at the same hours. There was a significant difference between time and treatments (p< 0.05). The difference of cell density was significant between control and metal concentrations, 2,4 mgl-1 with 6,8 mgl-1. In control groups, the cell density and chla content were increased with time. On the other hand, the content of chla and cell number reduced with Cu2+ . The concentration of Cu2+ from 2 to 8 mgl-1 inhibited cell density from 72.09% ( 2mg.l-1 , 96 h) to 92.33% ( 8mgl-1,96 h), respectively. In the Cu2+ treatments the death of algal biomass was observed in 24 h, but there was an increase in cell numbers of S.obliquus in control and the algae were still on exponential phase at 96 h. Manuscript profile -
Open Access Article
687 - شبیه سازی کشت سلول توسط Bioreactor بستر بسته بندی شده
مهیار خرم -
Open Access Article
688 - Using Molybdenum Trioxide as a TCO Layer to Improve Performance of CdTe/CdS Thin-film Solar Cell
Bahadour Mozafari Ali Shahhoseini -
Open Access Article
689 - New Fault-Tolerant Majority Gate for Quantum Dots Cellular Automata
Razieh Farazkish -
Open Access Article
690 - New Approach to Design and Implementation XOR Gate in QCA Technology
Somayeh Aghababaei Samira Sayedsalehi -
Open Access Article
691 - New Approach to Decreasing the Number of Quantum Dot Cells in QCA Inverter
Razieh Farazkish -
Open Access Article
692 - Comparative study of optimization algorithms for sizing of Wind Turbine/ Fuel Cell/ Electrolyzer/ Hydrogen Tank in the hybrid stand-alone power system
Hadi Razmi Hasan Doagou-Mojarrad Javad Olamaei -
Open Access Article
693 - Investigating the Effect of Different Penetration of Renewable Energy Resources on Islanded Microgrid Frequency Control Using a Robust Method
Amir Hosein Tayebi Reza Sharifi Amir Hosein Salemi Faramarz Faghihi -
Open Access Article
694 - Fault-Tolerant Techniques for Quantum-dot Cellular Automata Circuits and Systems
Razieh Farazkish Mani Zarei -
Open Access Article
695 - Side Lobe Canceller Structure-Based Spatial Interference Cancellation and performance enhancement of the MIMO wireless systems
Navab Ghaedi Ali Jamshidi Behrad Mahboobi Ramezan Ali Sadeghzadeh -
Open Access Article
696 - Robust Combined Control of Proton Exchange Membrane Fuel Cell Equipped by Boost Converter
Hassan Khosh Kholgh Sima Alireza Sahab Abdolreza Tavakoli Hossein Mahdinia Roudsari -
Open Access Article
697 - Comparison of the sensitivity of colored silica nanoparticle-based immunosensor with culture and PCR methods in detection of Brucella abortus
Arash Shams Bahareh Rahimian Zarif Mojtaba Salouti Reza Shapouri Sako MirzaiieBackground & Objectives: Brucellosis has always been a threat to the health and economy of the community. The limitations of human and animal disease detection methods justify the need for new diagnostic methods. This study was aimed to compare the sensitivity of co MoreBackground & Objectives: Brucellosis has always been a threat to the health and economy of the community. The limitations of human and animal disease detection methods justify the need for new diagnostic methods. This study was aimed to compare the sensitivity of colorimetric strategy based- immunosensors in the diagnosis of Brucella abortus with those of culturing and PCR methods. Materials & Methods: The colored silica nanoparticles and paramagnetic nanoparticles after synthesis were conjugated with polyclonal antibody to form EDC/NHS complexes to form probe sequences, respectively. These probes were collected after being added to serial dilutions of B. abortus and completing the reaction. Then, with releasing organic dye from the silica structure, absorbance intensity was measured at 670 nm. On the other hand, at the time of each dilution, the corresponding chromosomal DNA was extracted by a DNA extraction kit and used for PCR analysis. The results of all three tests were ultimately compared. Results: Based on the results, the detection range of the immunosensor and culture was the same and equal to 1.5×103 - 1.5×108 CFU mL-1. But, the limit of detection for immunosensor and culture was measured as 450 CFU mL-1 and 400 CFU mL-1, respectively. The results of the PCR test exhibited a wide dynamic range of 1.5×104 to1.5×108 CFU mL-1, with LOD of 5000 CFU mL-1.Conclusion: Comparing the results of this study showed that the proposed immunosensor is capable of replacing conventional B. abortus detection methods and can be considered as an on-site diagnostic tool, with high sensitivity. Manuscript profile -
Open Access Article
698 - Simulation of the production process of Aspergillus niger single cell protein base on un-structured kinetic models
Fatemeh Ardestani Roxana KasebkarBackground & Objectives: Design of the production of single cell proteins depends on definition of the growth template of the producer microorganisms. This study was aimed to evaluate the production of Aspergillus niger single cell protein and simulation of cell bio MoreBackground & Objectives: Design of the production of single cell proteins depends on definition of the growth template of the producer microorganisms. This study was aimed to evaluate the production of Aspergillus niger single cell protein and simulation of cell biomass production based on several un-structured models. Materials & Methods: In this experimental study, the fermentative process of single cell protein production was conducted in batch submerged culture with optimum culture medium formulation at 250C, pH 6 and 300 rpm for 200 h in an incubator shaker. At the end of process, the content of shaker flasks was used to analysis glucose concentration, cell dry weight and protein content in cell biomass. Results: The result simulation by Monod, Moser and Logistic models showed 92% 63% and 83% similarity, respectively. Increase in the pH from 3.5 to 6 caused 71% enhancement in protein content in cell biomass. However, pH more than 6 led to decrease in the cell biomass protein content and this values reached to 29% a pH 7. Increases in the initial glucose concentration from 10 to 50 g. L-1 did not show considerable effects on the cell biomass protein content. Cell biomass protein content of the media containing 50 g. L-1 initial glucose was only 5.67% more than the medium contained of 10 g. L-1 initial glucose. Conclusion: The Monod kinetic model was proposed as a suitable model to simulate A. niger behaviour. Furthermore, pH of the media affects cell biomass protein content. However, initial glucose concentration in the media did not show significant effects on the cell biomass protein content. Manuscript profile -
Open Access Article
699 - Transfection of Sf9 insect cells by recombinant Baculovirus containing Core+1 gene of HCV JFH1 genotype 2a in order to express Core+1 protein
Farideh Sadat Sajadian Fard Pooneh RahimiBackground & Objectives: Recently, a new protein, named Core+1, has been reported to be expressed through a +1 ribosomal frame shift in the Core protein coding region of Hepatitis C virus. The purpose of this study was to design a recombinant Baculovirus vector cont MoreBackground & Objectives: Recently, a new protein, named Core+1, has been reported to be expressed through a +1 ribosomal frame shift in the Core protein coding region of Hepatitis C virus. The purpose of this study was to design a recombinant Baculovirus vector containing HCV-2a (JFH1) Core+1 sequence, and also, to verify the production of this recombinant Core+1 protein in Baculovirus expression system. Materials & Methods: Core+1 gene of HCV-2a (JFH1) was synthesized into pUC57 plasmid. The synthesized target gene was sub-cloned into the plasmid pFastBac-HTA. The recombinant vector was used to transform the competent E. coli DH10Bac containing the donor clone. The recombinant Baculovirus bacmid was produced following transposition. Recombinant bacmid was verified by PCR and then was transfected into Sf9 insect cells to package a new recombinant Bbaculovirus. SDS-PAGE and Western blotting was used to confirm the expression of Core+1 protein in insect cells. Results: Sequence analysis and white-blue colony selection confirmed a successful cloning of the Core+1 sequence of HCV (JFH1) into the pFastBac-HTA vector and transformation of E. coli DH10Bac. Production of recombinant Baculovirus. The HCV-2a (JFH1) Core+1 protein was successfully expressed and confirmed in SDS-PAGE and Western blot. Conclusions: Baculovirus expression system provides a high yield post-translational modification tool for HCV Core+1 protein expression, which is similar to Core+1 protein produced during natural infection with HCV. Manuscript profile -
Open Access Article
700 - Molecular characterization and evaluation of the antibacterial properties of Pediococcus pentosaceus isolated from whole barley sourdough
Alireza Sadeghi Mojtaba Raeisi Maryam Ebrahimi Balal SadeghiBackground & Objectives: Usually identification and characterization of ecosystems isolates of lactic acid bacteria (LAB) which have been rarely studied lead to obtaining LAB with unique characteristics. The aims of this study were molecular characterization and eva MoreBackground & Objectives: Usually identification and characterization of ecosystems isolates of lactic acid bacteria (LAB) which have been rarely studied lead to obtaining LAB with unique characteristics. The aims of this study were molecular characterization and evaluation of the antibacterial properties of dominant LAB isolated from whole barley sourdough. Materials & Methods: In this experimental study, first the sourdough was prepared from the whole barley flour, and subsequently its dominant LAB was isolated. LAB isolate was identified by sequencing of PCR products. Antibacterial properties of the isolate and its cell free culture filtrate (CCF) which was obtained from logarithmic and stationary phases as crud and naturalized form were also investigated for some food-borne indicator bacteria using well diffusion and microdilution methods, respectively. Results: Sequencing results of PCR products lead to identification of Pediococcus pentosaceus as the dominant LAB in whole barley sourdough. This LAB isolate had more antagonistic effect (p<0.05) on Listeria monocytogenes than other indicator bacteria. Furthermore, crud CCF obtained from logarithmic phase of the isolate had the highest bacteriocin activity and antibacterial ability in comparison to other CCFs. Conclusion: Whole barley sourdough P. pentosaceus isolate and its CCF have proper antibacterial properties against food-borne indicator bacteria used in this study. Therefore, P. pentosaceus has high potential to be used as microbial starter or adjunct culture in processing fermented foods instead of chemical preservatives or antibiotics in order to increase shelf life and safety of these products. Manuscript profile -
Open Access Article
701 - Investigation of antifungal effect of nanoparticle-encapsulated curcumin on CDR1 gene expression in fluconazole-resistant isolates of Candida albicans
Hadiseh Golpour Najmeh Ranji Seyedeh Hajar SharamiBackground & Objectives: Curcumin as a natural phenolic compound derived from Curcuma longa plant has shown an antifungal property. Candida albicans is the most common opportunistic fungal pathogen. Continuous deployment of antifungals against this pathogen has led MoreBackground & Objectives: Curcumin as a natural phenolic compound derived from Curcuma longa plant has shown an antifungal property. Candida albicans is the most common opportunistic fungal pathogen. Continuous deployment of antifungals against this pathogen has led to the emergence and increasing of the multi-drug resistance. In this study, the effect of nanoparticle-encapsulated curcumin on CDR1 gene expression was evaluated in fluconazole-resistant isolates of C. albicans. Materials & Methods: In this study, 6 fluconazole-resistant isolates of C. albicans were treated just by fluconazole (1/2MIC) as the control sample and in the combination with nanoparticle-encapsulated curcumin as the test sample. After 24h, two cell groups were cultured in Sabouraud Dextrose Agar to estimate cell death percentage. Following RNA extraction and cDNA synthesis, CDR1 gene expression was investigated quantitatively by real-time PCR method in both curcumin-treated and untreated cells. Results: Our findings showed that the combination of fluconazole (1/2MIC) and nanoparticle-encapsulated curcumin treatment reduces the fungal growth by 50% after 24 h. Moreover, quantitative real-time PCR analysis revealed that nanoparticle-encapsulated curcumin decreases the expression level of CDR1. Conclusion: Our findings suggested that curcumin can inhibit fungal growth through different mechanisms such as decreasing the number of ABC efflux pumps at the cell surface and synergically increases the antifungal effect of fluconazole in resistant isolates of C. albicans. Manuscript profile -
Open Access Article
702 - Antimicrobial effects of extracellular copper sulfide nanoparticles synthesized from Bacillus licheniformis
Morahem Ashengroph Maryam Sahami-SoltaniBackground & Objectives: Copper nanoparticles due to unique catalytic properties and electrical and optical conductivity are of great importance. This study was aimed to use the potential of aquatic bacteria as biocatalysts to reduce copper sulfate into copper sulfi MoreBackground & Objectives: Copper nanoparticles due to unique catalytic properties and electrical and optical conductivity are of great importance. This study was aimed to use the potential of aquatic bacteria as biocatalysts to reduce copper sulfate into copper sulfide nanoparticles (CuSNPs) and to assess its antimicrobial properties.Materials & Methods: The CuSNPs produced via bioconversion reaction have been characterized by spectroscopy analysis, electro-micrographs prepared by scanning electron microscopy (SEM) and particle size distribution histogram. The antimicrobial activity of CuSNPs against some bacteria and pathogenic fungi was also investigated by disc diffusion test.Results: 105 Cu-resistant bacterial strains have been isolated according to selective enrichment technique. Based on the results, the only culture supernatant of strain Cu25 was able to reduce copper sulfate into copper sulfide nanoparticles (CuSNPs), extracellular. The cu25 strain was identified as Bacillus licheniformis based on phenotypic and molecular analysis. Subsequently, the extracellular synthesis of CuSNPs was investigated. The results showed that the supernatant of B. licheniformis Cu25 following exposure to 7.5 mM copper sulfate solution and 24 h of incubation can produce spherical CuSNPs with the average diameter of 21.5 nm as extracellular.Conclusion: The current study is the first report on the extracellular synthesis of CuSNPs using B. licheniformis. Also, the produced biological nanoparticles have growth inhibitory effect against some pathogenic bacteria and fungi. Manuscript profile -
Open Access Article
703 - Evaluation of adherence of probiotic Lactobacilus casei to Hep2– cell line
Zeinab Takalloo Mahdi Goudarzvand Zohreh KhodaiiThe first step to choose a strain as probiotic is capability for the bacteria to adhere to mucosal adhesion due to increase the prevention of the adherence of pathogenic bacteria, and the secretion of antimicrobial agents, which produce an appropriate condition of micro MoreThe first step to choose a strain as probiotic is capability for the bacteria to adhere to mucosal adhesion due to increase the prevention of the adherence of pathogenic bacteria, and the secretion of antimicrobial agents, which produce an appropriate condition of microbial growth. This study was aimed to evaluate the adherence ability of Lactobacilus casei to Hep-2 cell line. First, the HEp-2 cells were grown in RPMI medium containing fetal calf serum and antibiotics. The defined numbers of probiotic bacteria grown in MRS broth were added to the HEp-2 cell. Then, the cells were washed after attachment of bacteria to the plates. Thereafter, the cells were stained and fixed with histological methods. The adhesion ability of bacteria and the pattern of adhesion was observed under optical microscope. Our results showed that L. casei was able to adhere to oro- pharyngeal cell line. Also, the optimum time to test the ability was 3 hours. These results indicated that the probiotic bacterium L. casei is suitable for application in health products. Based on these results, we recommend application of L. casei in oral hygiene products. Manuscript profile -
Open Access Article
704 - Applications of iron oxide nanoparticles in microbiology and the effects on microorganisms
Alireza Ebrahiminezhad Aydin Berenjian Seyyed Amin Kohpayeh Yones GhasemiA broad application of nanostructures in various fields of science has led to their commercialization in different industries. For instance, application of the antimicrobial activity of nanosilver is one of the consequences of such these strategies. Furthermore, iron ox MoreA broad application of nanostructures in various fields of science has led to their commercialization in different industries. For instance, application of the antimicrobial activity of nanosilver is one of the consequences of such these strategies. Furthermore, iron oxide nanoparticles is currently employed in microbial cell fixation. In addition, nanoparticles can be used for effective targeted drug delivery to the site of infection. In this term, study on the effect of iron oxide nanoparticles on the physiology of microorganisms is highly demanded. At low concentrations, since iron oxide nanoparticles can act as iron source of microorganisms, they may be eliminated from microbial environment. However, higher concentrations of these particles can result in cell stress and reduction in microbial cell growth. These nanoparticles attach to the microbial cell wall via electrostatic and hydrophobic forces, reducing microbial pathogenicity. The attachment of iron oxide nanoparticles to bacterial cell wall interferes in functionality of cell membrane and thereby increase membranes permeability. These phenomenon increases molecular transportation through the cell membrane and increases productivity in industrial process. Manuscript profile -
Open Access Article
705 - Evaluation of the synergistic effect of bacterial recombinant alginate lyase and therapeutic antibiotics on the growth of planktonic Pseudomonas aeruginosa
Hadis Tavafi Ahya Abdi- Ali Parinaz Ghadam Sara GharaviBackground & Objectives: Alginate is one of the most important virulence factors of Pseudomonas aeruginosa. This study aimed to evaluate the synergistic effect of recombinant alginate lyase and common antibiotics in the treatment of Pseudomonas&n MoreBackground & Objectives: Alginate is one of the most important virulence factors of Pseudomonas aeruginosa. This study aimed to evaluate the synergistic effect of recombinant alginate lyase and common antibiotics in the treatment of Pseudomonas infections on the growth of planktonic cells of P. aeruginosa. Materials & Methods: In this study, P. aeruginosa TAG48 was isolated and identified from the clinical sample. To purify alginate lyase and its effect on planktonic cells, the alginate lyase gene (algL) was isolated, cloned, sequenced and expressed. The resultant enzyme was purified by affinity chromatography. The ciprofloxacin, tobramycin, and cefixime were also used to test the effectiveness of these antibiotics on planktonic cells of P. aeruginosa by carrying out MIC, MBC. The synergistic effects of these antibiotics and the recombinant alginate lyase enzyme on planktonic cells were evaluated. Results: Our results indicated that the antibiotics and the enzyme have shown MIC for ciprofloxacin, tobramycin, cefixime and enzyme in the following concentrations: 4, 16,128 and 9.37 μg/ml, respectively. MBC was also calculated equal to MIC. Also, alginate lyase exhibited synergy with tobramycin and cefixime on the growth of planktonic cells of P. aeruginosa TAG48 but not with ciprofloxacin. Conclusion: Regarding the importance of alginate in the pathogenicity of P. aeruginosa, its degradation could reduce this characteristic of the bacteria. Detection of novel algL genes in bacterial communities can also lead the way for the study of alginate lyases with specific activities against alginates from pathogenic bacteria in microbial samples. Manuscript profile -
Open Access Article
706 - Optimizing the HS medium for the production of microbial cellulose nanofibers using Acetobacter xylinum
Fatemeh Nouri Rouzbahani Fatemeh Ashrafi Soheila Moradi BidhendiBackground & Objectives: Bacterial cellulose synthesized by some microorganisms, including Acetobacter xylinum, has been widely used in various industries due to its specific properties. The purpose of this study was to optimize the cultivation condition for the pro MoreBackground & Objectives: Bacterial cellulose synthesized by some microorganisms, including Acetobacter xylinum, has been widely used in various industries due to its specific properties. The purpose of this study was to optimize the cultivation condition for the production of microbial cellulose in a new culture medium. Materials & Methods: In this experimental study, new sources of carbon and nitrogen were added to the Hestrin-Schramm medium, containing A. xylinum, and incubated for 7 days under static conditions. Carbon sources included glucose, galactose, fructose, lactose, sucrose, maltose, ethanol, methanol, inositol, glycerol, xylose, and mannitol and nitrogen sources included ammonium sulfate, ammonium nitrate, sodium nitrate (1, 3, 6, 9 g/l HS medium), peptone and yeast extract (5, 10, 15, 20 g/l HS medium). Sodium alginate and sodium acetate were used to investigate the viscosity effect and to adjust the medium pH. Scanning electron microscopy, X-ray diffraction, and FTIR spectroscopy technique were used in order to confirm the cellulose production. Sodium alginate and sodium acetate were used to investigate the viscosity effect and determine the pH adjustment. Scanning electron microscope, X-ray diffraction and FTIR spectroscopy technique were used in order to confirm the cellulose production. Results: Four carbon sources including glycerol (without a significant drop in pH), glucose, fructose, and inositol produced the highest amount of cellulose, respectively. Organic nitrogen sources, particularly peptone, had a great impact on cellulose production, unlike mineral nitrogen sources. The optimum amount of sodium alginate as the viscosity agent and sodium acetate as the buffer was 1.2 and 3 gram per liter of culture medium, respectively. X-ray diffraction showed the highest crystallinity index in medium containing glucose, fructose, inositol, and glycerol, respectively. The amount and intensity of infrared absorption in FTIR scanning of the products of culture media containing glucose and glycerol and comparing them with other similar cellulose graphs confirmed the cellulose production. Furthermore, Scanning Electron Microscopy studies clearly showed a nanofiber structure of microbial cellulose in media with better carbon sources. Conclusion: According to our findings, glycerol and peptone have the most impact on microbial cellulose production. It was also indicated that addition of 2.1 g/ L sodium alginate to the culture medium as the viscosity agent along with pH control during the process by adding 3 g/ L sodium acetate can have a significant effect on cellulose production. Manuscript profile -
Open Access Article
707 - Effect of Vincristine on miRNA-15a expression in Epstein‐Barr‐Virus transformed B cell-CO 88BV59-1 LCL
Abdolreza Sotoodeh Jahromi Mohammad Kargar Maliheh Moradzadeh Farshid Kafilzadeh Marzieh JamalidoustBackground: Despite advances in diagnosis and therapy, cancer is still the main cause of death in world. Vincristine is one the major drug in tumor treatment. However, the anti-lymphoma effects of Vincristine on micro-RNA expression are not clear, especially in B cell l MoreBackground: Despite advances in diagnosis and therapy, cancer is still the main cause of death in world. Vincristine is one the major drug in tumor treatment. However, the anti-lymphoma effects of Vincristine on micro-RNA expression are not clear, especially in B cell lymphomas. The aim of the present study was to evaluate the effects of Vincristine on miRNA-15a3p and miRNA-15a5p genes expression Epstein‐Barr‐Virus (EBV)-infected transformed B cell lymphoma.Material and Methods: In this study, the effects of cyclophosphamide on CO 88BV59-1 LCL – an EBV infected transformed B cell was evaluated. The cells were treated with Vincristine (0.05-50 µM), for 24-72 hours. MTT, flow cytometry and real-time PCR techniques were used for cell viability, and cytotoxicity evaluations and miRNA-15a genes expression, respectively. Results: Vincristine significantly inhibited proliferation and induced cell death in EBV infected cell-line in a dose and time-dependent manner (P<0.05). There were no significant changes in the expression of miRNA-15a3p and miRNA-15a5p in treated cells compared to untreated cells (P>0.05).Conclusions: The results showed that cytotoxic effects Vincristine on CO 88BV59-1 LCL is independent on miRNA-15a3p and miRNA-15a5p expressions. Manuscript profile -
Open Access Article
708 - Cloning and expression of H gene of PPRV in baculovirus expression system
Mehdi Taheri Asl majid moghbeli Mohammad Kargar mohsen lotfi Farshid KafilzadehBackground and Objectives: Small ruminant plague is one of the most economically important pathogens in sheep and goats caused by morbilli viruses. Protein H is one of the major proteins for immunity against PPRV. The aim of the present study was to clone and express th MoreBackground and Objectives: Small ruminant plague is one of the most economically important pathogens in sheep and goats caused by morbilli viruses. Protein H is one of the major proteins for immunity against PPRV. The aim of the present study was to clone and express the H gene of this virus by the baculovirus expression system.Materials and Methods: H gene was amplified by RT-PCR and specific primers and then cloned into pFastBac Dual plasmid. The recombinant vector with the gene was transferred to the DH10Bac host cell. By transfection Sf9 cell with recombinant vector, its expression and characteristics were evaluated by SDS-PAGE, western blotting and Bradford methods.Results: The H gene was amplified using specific primers from the PPR virus genome and the specific band was obtained. Cloning of the H gene on the pFastBac Dual vector and baculovirus genome was proved with PCR and enzymatic digestion. By transfection the recombinant vector into Sf9 cells and performing sequential passages, the recombinant protein was shown to be completely pure and specific using SDS-PAGE, Western blotting and Bradford methods. The expression level of this gene was obtained 218 µg/ml.Conclusion: Considering the production of an appropriate amount of recombinant H protein, this protein can be a suitable candidate for the production of recombinant vaccine against PPRV. Manuscript profile -
Open Access Article
709 - Comparing the effect of metronidazole with pyocyanin pigment extracted from Pseudomonas aeruginosa on Trichomonas vaginalis in-vitro
sara abdizadehjavazm zohreh momeni mona farhadiBackground and Objectives: Pyocyanin is a blue pigment with oxidation and reduction potential and metabolically active, which has medicinal effects on eukaryotic and prokaryotic cells. Trichomonas vaginalis is the causative agent of trichomoniasis, the most important no MoreBackground and Objectives: Pyocyanin is a blue pigment with oxidation and reduction potential and metabolically active, which has medicinal effects on eukaryotic and prokaryotic cells. Trichomonas vaginalis is the causative agent of trichomoniasis, the most important non-viral sexually transmitted disease in the world. The aim of this study was to evaluate the effect of pyocyanin extracted from Pseudomonas aeruginosa on Trichomonas vaginalis and PC12cell line. Materials & Methods: This study was carried out by an interventional method. First, pyocyanin was extracted from Pseudomonas aeruginosa strain RTCC1474 with the help of chloroform. The relative purity of the pigment was determined by thin-layer chromatography, spectrophotometry UV-Vis and FTIR. Its effect in different concentrations were investigated on Trichomonas vaginalis and PC12 cell line. Results: Pyocyanin at a concentration of 10,000µg/ml in 24 hours and concentrations of 5,000 and 2,500µg/ml in 48 hours caused 100% inhibition of the parasite growth. Its IC50 (Inhibitory Concentration of 50%) level in 48 hours was 17.44µg/ml and the CC50 of this pigment on the cell line was 930 µg/ml, so pyocyanin is effective against the Trichomonas vaginalis and its toxicity on the cell line is 53 times higher than of the parasite (SI=53/32). Conclusion: Considering the inhibitory effect of pyocyanin on the growth of Trichomonas vaginalis based on the results, it is possible that with further research on the extraction and purification of this pigment from various isolates of Pseudomonas aeruginosa, and with additional tests in vitro and in vivo, a more accurate judgment regarding the antiparasitic power of this pigment can be expressed. Manuscript profile -
Open Access Article
710 - A Comparative study of ICC-RT-PCR and Cell Culture methods for detection of Enteroviruses in Sewage
Mohammad Kargar Sara Sadeghipour Hamideh Tabatabaee Rakhshandeh NateghBackground and objectives: Enteroviruses are one of the most important enteric viruses which produce a broad range of human diseases. But being time consuming and also the necessity to perform confirmed tests for Enteroviruses detection, using molecular direct methods h MoreBackground and objectives: Enteroviruses are one of the most important enteric viruses which produce a broad range of human diseases. But being time consuming and also the necessity to perform confirmed tests for Enteroviruses detection, using molecular direct methods have been recently considered. The aim of this research is evaluation of ICC-RT-PCR and cell culture methods for detection of enteroviruses in sewage system. Materials and methods: In this research 63 specimens were provided through Grab sample method which concentrated by pellet & Two-phase method and cultured in RD and HEp-2 cells respectively. All specimens, then, were inoculated using sensitive cell cultures of RD and HEp-2. After 24 hours incubation at 360C by means of Pan E.V primers and afterwards Pan P.V Primers along with specific sabin primers, test of RT-PCR was carried out on the cell culture specimens. Results: Out of all collected specimens, enteroviruses were isolated from 33 specimens (52.38%) and 41(65.01%) specimens which utilized cell-culture & ICC-RT-PCR methods respectively. Polioviruses were also isolated from 6 specimens. Conclusion: Statistical analysis indicated that there is a significant relationship (p= 0.05) between cell culture and ICC-RT-PCR methods for isolating enteroviruses. Further the sensitivity of ICC-RTPCR method to detect enteroviruses less than 0.01 TCID50 was evaluated, which can indicated the acceptability and sensitivity of this method for detection of enteroviruses in sewages. Manuscript profile -
Open Access Article
711 - Comparison of function of immobilized and free Bacillus licheniformis cells in production of alkaline protease
Mohammad Mashhadi-Karim Mehrdad Azin Seyyed Latif Mousavi Gargari Meysam SarsharAbstract Background and Objective: Proteases are an important group of industrial enzymes, which are widely used in different industries such as detergent, leather tanning, pharmaceutical, and food industries. The aim of this study was to immobilize Bacillus lichenifor MoreAbstract Background and Objective: Proteases are an important group of industrial enzymes, which are widely used in different industries such as detergent, leather tanning, pharmaceutical, and food industries. The aim of this study was to immobilize Bacillus licheniformis cells in calcium alginate beads and study of its effects on the amount of alkaline protease production. Effects of several different conditions on stability of the beads were also examined. Material and Methods: Bacillus licheniformis cells were immobilized in calcium alginate beads and were used for production of alkaline protease. The amount of enzyme production was compared in immobilized and free-cell fermentation. Effect of stuffing rate (%) on the enzyme production was studied. Optimum pH and temperature of enzyme activity were also determined. Furthermore, effects of pH, curing time and treating the beads by glutaraldehyde on stability of the beads were examined. Results: In this study the amount of production and productivity of protease in immobilized cells state showed an increase of 74% and 54% in comparison to free cells state, respectively. The highest amount of the production of the enzyme was obtained in stuffing rate of 5% (v/v). Optimum pH and temperature of the enzyme activity were determined 8 and 65oC, respectively. The highest stability of the beads was observed at curing time of 1 hour at pH of 7.4. Treating the beads by glutaraldehyde was detrimental to their stability. Conclusion: Use of immobilized cells of Bacillus licheniformis in calcium alginate beads on the one hand, can increase productivity of the alkaline protease in comparison to free cells method, and on the other hand, reduces the cost of the enzyme production because of eliminating the need of preparation of inoculum for the new batches. Manuscript profile -
Open Access Article
712 - An analysis for assay role of Nonpolio Entreviruses for cause of AFP in Iran, by five cell lines
Firouz Abbasian Hamideh Tabatabaei Mahboubeh Sarijlou Rakhshande NateghBackground and objectives: AFP (Acute flaccid paralysis) is a suddenly weakness of any organs of body that its symptoms reach to peak after 4-5 day, but it don't progress. AFP has much etiology that Poliovirus is more important than others. At currently, Poliovirus has MoreBackground and objectives: AFP (Acute flaccid paralysis) is a suddenly weakness of any organs of body that its symptoms reach to peak after 4-5 day, but it don't progress. AFP has much etiology that Poliovirus is more important than others. At currently, Poliovirus has been eradicated in most countries, and then we must analysis role of nonpolio agent in this disease. Material and Methods: In this work, all of stool specimens of AFP patient (2003) inoculate to five cell line (L20B, RD, Hep-2, Vero and GMK). And have evaluted with micronutrilization tests. Results: We inoculate two specimens from any 460 case fewer than 15 years AFP patient to these five lines. Ultimately, we isolated 34 different species and serotypes of Entroviruses. Upon this result, 7.1% of all cases were positive for cell culture and isolation of Entroviruses. Sexuality doesn't have an effective role in isolation of Entroviruses. Most of these viruses isolated from less than 0-5 year's children and it decline by increase in age. Echoviruses (12 cases) and Polioviruses (12 cases) have been isolated more than others. Conclusion: We showed a meaningful difference between RP (Residual Paralysis) positive and RP negative cases. Upon this result, we showed nonpolio Entroviruses can cause RP. It doesn't have meaningful difference isolation of Vaccine Poliovirus between RP positive and RP negative patient. Then we showed OPV vaccines used in Iran, have enough safety. The difference in isolation of Coxsacie virus between RP positive and RP negative is not meaningful. We demonstrate Echoviruses can cause AFP in patient fewer 5 years, because the difference in isolation of Echoviruses between RP positive and RP negative patient is meaningful. Manuscript profile -
Open Access Article
713 - Presence of clade D Zooxanthellae in dominant Sclerectinian and soft corals in Larak island, Persian Gulf
Mohammad Hassan Shahhosseiny Pargol Ghavam Mostafavi Gholamhossein Vosughi Sanaz AzadbodyAbstract Background and Objectives: Dominant sclerectinian and soft corals contain the symbiotic single cell called zooxanthel MoreAbstract Background and Objectives: Dominant sclerectinian and soft corals contain the symbiotic single cell called zooxanthellae which have important role in preparing organic material for coral requirements. The coral reefs of this area in the gulf are always under effects of environmental conditions, such as subtropical latitude, temperature and salinity variations, changing symbiotic zooxanthellae. The aims of this study was identification of Symbiodinium clades and presence of clade D in sclerectinian and soft corals of Larak island by molecular methods. Materials and Methods: Three soft coral species and five sclerectinian coral species were collected from north and north east of Larak island, respectively. After DNA extraction, partial 28S ribosomal DNA of Symbidinium were amplified by polymerase chain reaction (PCR). Then PCR products were analyzed by phylogenetic analyses of the partial 28S ribosomal sequence. Results: To follow amplification of 28S large ribosomal subunit gene, the 780 bp PCR products were sequenced and were compared to the gene bank. The results showed that all the symbiotic clades of soft corals in Larak Island belonged to clade D. Conclusion: Dominance of clade D in sclerectinian and soft corals in Larak island due to of high temperature in the Persian Gulf and unstable condition of Hormoz strait is normal and natural. Manuscript profile -
Open Access Article
714 - Study of ability Fusarium oxysporum fungi in extracellular biosynthesis of silver nanoparticle in vitro
Golshid Sajjadi Abolfath Shojaiee Mohammad Reza Fazeli Javid Amini Hossain JamalifarBackground and Objective: Development of methods without using plotant and poisonous material and minimum wastes to produce under control nano structures is of nanotechnologist concerns. In this way biologists, by previous knowledge, nano-scale minerals controlled makin MoreBackground and Objective: Development of methods without using plotant and poisonous material and minimum wastes to produce under control nano structures is of nanotechnologist concerns. In this way biologists, by previous knowledge, nano-scale minerals controlled making by microorganism, seeking organism capable making non-organic nanoparticles. The aim of this study is extracellular production of silver nanoparticles with maximum dimention of 20 nm by Fusarium oxysporum fungi. Materials and methods: After studies to optimize growth condition, Fusarium oxysporum biomass in a medium containing yeast and malt extract is reproduced. After silver nanoparticles production in silver nitrate solution, this nanoparticles are studies by UV-Visible Spectrophotometry and Transmission Electron Microscopy (TEM) methods. Results: Studies showed that when Fusarium oxysporum biomass put in 10-3 M of silver ions, can produce silver nanoparticles in the form of extracellular. Conclusion: Because of physical and chemical particular properties of silver nanoparticles with maximum diameter of 20 nm of Fusarium oxysporum fungi, its industrial production and applied evaluation is offered. Manuscript profile -
Open Access Article
715 - The Inhibitory Effect of Doxycycline- Silver Nanoparticle Conjugate on Brucella melitensis
Mohsen Ajalli Mojtaba Salouti Hamed Alizadeh Zahra Heydari Hossein Hamzehei Aram AlizadehBackground and Objective: Brucellosis is a zoonotic disease caused by Brucella bacteria. According to recent studies, antimicrobial activity of silver nanoparticle was approved. The aim of this study was to investigate the antimicrobial activity of Doxycycline - silver MoreBackground and Objective: Brucellosis is a zoonotic disease caused by Brucella bacteria. According to recent studies, antimicrobial activity of silver nanoparticle was approved. The aim of this study was to investigate the antimicrobial activity of Doxycycline - silver nanoparticles conjugate against Brucella meltensis 16M. Material and Methods: After preparing the doxycycline-silver nanoparticle conjugate, its antimicrobial activity against Brucella meltensis 16M was determined by Well Diffusion Agar method in Muller Hintone Agar media. Also, Minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of Doxycycline-silver nanoparticle conjugate was determined by Macrodilution method in Muller Hintone Broth media. Finally, antibacterial effect of the nanoparticle was assayed in animal model. Results: The results showed that Doxycycline-silver nanoparticle conjugate has antimicrobial activity against Brucella melitensis 16M in laboratory condition. In mouse model, the conjugate of Doxycycline-silver nanoparticle could decrease effectively the Brucella melitensis load in liver. Conclusion: This study demonstrated that Doxycycline-silver nanoparticle conjugate has synergistic effect on Brucella melitensis 16M and can be useful in treatment of brucellosis. Manuscript profile -
Open Access Article
716 - The comparison between molecular and bacteriological detection for identification of abortion agents caused by Brucella and Salmonella in sheep in Shahrekord town
Ali Sharifzadeh Abbas Doosti Mohsen GaafarianBackground and Objective: Brucella spp and Salmonella abortus ovis are important causes of ovine abortion around the world. Both Bacteria can be serologically diagnosed, but many factors may cause false positive and negative results. Direct methods based on bacteriologi MoreBackground and Objective: Brucella spp and Salmonella abortus ovis are important causes of ovine abortion around the world. Both Bacteria can be serologically diagnosed, but many factors may cause false positive and negative results. Direct methods based on bacteriological isolation are usual, but they are difficult, time consuming and dangerous. Polymerase chain reaction (PCR) have been successfully described for the detection of Brucella spp. and Salmonella abortus ovis. Material and Methods: The detection of these agents in aborted ovine fetuses by multiplex PCR is described. The mPCR was applied to 38 fetal stomach contents. 5(13.1%) samples collected from ovine fetus were Brucella spp. Results: 19 (50%) samples collected were salmonella abortus ovis. 10 (26.3%) samples collected were negative and 4 (10.6%) samples collected were Brucella spp. and Salmonella abortus ovis .in Bacteriological examination 5(13.1%)samples collected from ovine fetus were Brucella spp. 9(23.7%)samples collected were salmonella abortus ovis and 24 (63.2%) samples collected were negative. Conclusion: Simplicity and the possibility of detection of both bactera in a single tube reaction support the use of the mPCR in the routine diagnosis. Manuscript profile -
Open Access Article
717 - Suspension culture of Neospora caninum using lymphocyte transformed by Theileria lestoquardi
Shamsi Ezhdahakosh pour Mohammad Mehdi Namavari Nahid Naghshgar Abdollah Rahimian Maryam Mansoorian Masoume HayatiBackground and Objectives: Neospora caninum is one of main etiologic factors of abortion in in cattle. The mass production of protozoa in laboratory conditions is performed based on growing in different cell lines. Since using suspension cell lines are very cost e MoreBackground and Objectives: Neospora caninum is one of main etiologic factors of abortion in in cattle. The mass production of protozoa in laboratory conditions is performed based on growing in different cell lines. Since using suspension cell lines are very cost effective for mass production of biological products, this study aimed to evaluate the suspension cell culturing for production of this protozoan. Materials and Methods: This study was experimentally performed bases on growth of N. caninum tachyzoites on Ka6 cell line (a cell line obtained from cattle infected with Theileria lestoquardi, Razi Institute, Shiraz, Iran. Next, based on MTT assay, ability of this cell culture for production of N. caninum was compared with Vero cell as the best current cell line for this purpose. Results: The results showed that N. caninum tachyzoites could enter into K6a cell lines and after replication released from the cells successfully. Replication of the tachyzoites was significant in both Vero and K6a cell lines in compare to the control. Conclusion: To our knowledge, this is the first and successful report of suspension culture of N. caninum tachyzoites. Although, the rate of N. caninum proliferation on Ka6 cell line did not show any significant difference in compare to Vero cell line, since Ka6 cell line is a transformed lymphocytic cell and it is possible to grow massively this cell line as suspension bioreactors, it is preferred to Vero cell line. Manuscript profile -
Open Access Article
718 - A confocal-microscopic study on HCV core+1 protein expression
Hassan Noorbazargan Atieh Hashemi Mohamadreza Aghasadeghi Arash Memarnejadian Mahdi Assmar Farzin RoohvandBackground and Objectives: Core+1 or F protein is recently identified to be encoded by hepatitis C virus (HCV) genome. Although functional properties of this protein are not still discovered, core+1 seems to play important roles in viral life cycle and pathogenesis. Thi MoreBackground and Objectives: Core+1 or F protein is recently identified to be encoded by hepatitis C virus (HCV) genome. Although functional properties of this protein are not still discovered, core+1 seems to play important roles in viral life cycle and pathogenesis. This study seeks to clone and express HCV core+1 gene in a eukaryotic system with the final aim of evaluating its potential roles in cell signaling pathways and resistance of HCV to therapy. Material and Methods: Core+1 gene corresponding to the amino acids 1-162 was PCR-amplified from the original gene of subtype b that was previously cloned in a prokaryotic vector (14). The amplicon harboring 6xHis-tag at C-terminal was subsequently subcloned in the eukaryotic pCDNA3.1+ vector. The Nhe I / BamHI restriction sites, initiation and stop codons as well as kozak sequences were designed in the primers. Constructed plasmid was verified by restriction enzyme analysis and sequencing reactions. Liver cell line of Huh7 was transfected with this plasmid using electroporation and lipofection techniques. Transfection efficiency was checked by co-transfection of pEGFPN1 plasmid and flowcytometry. Finally expression and localization of core+1 protein was evaluated by means of confocal microscopic technique. Results: Restriction enzyme analysis and sequencing reactions indicated the accuracy of cloning procedure. Flow cytometric analysis showed higher electroporation efficiency for transfection of Huh7 cells, in comparison with lipofection method. Finally, results of confocal microscopic microscopy using anti-His antibody confirmed the transcription and expression of core+1 protein in Huh7 cells. Conclusions: Our study resulted in the eukaryotic expression of core+1 protein in Huh7 cells and provided an appropriate tool for future studies on the potential interference of core+1 with intracellular signaling pathways and cellular protein interaction. Manuscript profile -
Open Access Article
719 - Isolation of Theileria lestoquardi Sporozoite in order to Produce a New Cell Line Buket
Nahid Naghshgar Mohammad Mehdi Namavari Shamsi Ezhdahakosh pour Mohammad Abdi Goodarzi Mohammad Hosein Hoseini Kasra Esmail nia Masoume Hayati Omid Reza Amr abadiIntroduction and Objectives: Malignant sheep and goats theileriosis is one of the most important protozoan diseases of sheeps in Iran. Theileria lestoquardi is the only intracellular eukaryotic pathogen that is able to transform its host cells reversibly. Therefore, des MoreIntroduction and Objectives: Malignant sheep and goats theileriosis is one of the most important protozoan diseases of sheeps in Iran. Theileria lestoquardi is the only intracellular eukaryotic pathogen that is able to transform its host cells reversibly. Therefore, design of a cell line of ovine lymphocyte that is transformed by the T. lestoquardi is very valuable. Materials and Methods: The breeding ticks was infected by feeding on the sheeps that were carrier of Theileria lestoquardi sporozoite in order to obtain homogeneous infected ticks. Then, ovine lymphocytes were infected with Theileria lestoquardi sporozoite stabilate to produce lymphocytic cell line containing T. lestoquardi. Result: This research resulted in the development of a new ovine lymphocytic cell line called as Booket. Molecular study confirmed that the cell lines were transformed by T. lestoquardi. The gene sequence of this isolate has been submitted to GenBank with accession no. GU233776. Conclusion: In this study the second lymphocytic cell line containing T. lestoquardi was established in Iran. Manuscript profile -
Open Access Article
720 - Production of cellulose from native bacterial isolates isolated in Iran
Raheleh Taheri Hatef Ajudanifar Parastoo PouraliBackground and Objectives: The microbial cellulose which is produced by some strains of Acetobacter and Gluconobacter is structurally similar to plant cellulose. Based on this feature, the microbial cellulose has been used in medical and industrial productions as an imp MoreBackground and Objectives: The microbial cellulose which is produced by some strains of Acetobacter and Gluconobacter is structurally similar to plant cellulose. Based on this feature, the microbial cellulose has been used in medical and industrial productions as an important raw material. The aims of this study were to isolate the native bacteria species producing cellulose and to evaluate their production rate. Materials and Methods: In this study, 65 samples were collected from different types of local vinegars, juices and fruits and were cultivated in Hestrin-Schramm's agar medium. Afterward the isolates with maximum ability to produce cellulose were selected and identified using biochemical tests and PCR method. After purification of the cellulose, enzymatic digestions method by cellulase enzyme and scanning electron microscope were used to confirm the presence of cellulose. Results: Totally, 20 strains with the cellulose production ability were isolated, of them 5 strains with maximum production ability were selected for further investigation. Base on biochemical tests and sequencing method, theses isolates were classified as Acromobacter spanius, Pseudomonas luteola and Pseudomonas durifulva. In this study, the wet and dried weight of the cellulose production were measured as 16.6 and 0.1g, respectively. Conclusion: According to the findings, the cellulose can be produced by native isolates other than Acetobacter and Gluconobacter. In this study, the new native strains of produced cellulose were introduced for the first time in Iran. Also, the produced cellulose by these species has suitable traits in comparison with standard strains. Manuscript profile -
Open Access Article
721 - Introduction of the Handwritten Miscellany No. 156 of the Majles Library Regarding its Literary and Research Val
Asghar Bahari Seyyed Mehdi Nourian Atamohammad RadmaneshAlongside the collection of poems and the poets’ biographies, the dictionaries, the Amsal-o-Hekam books, the nonliterary works and poetry miscellany and collections are considered as the most important references of the literature and Farsi language where one can MoreAlongside the collection of poems and the poets’ biographies, the dictionaries, the Amsal-o-Hekam books, the nonliterary works and poetry miscellany and collections are considered as the most important references of the literature and Farsi language where one can come across a lot of samples of poems of the poets. The value of the recent type- that is, the poetry miscellany and poetry collections although not as much as the poetry collections and the poets’ biographies, one can gain access to poems and works that can be counted as the sole trustworthy references in some literary researches. Among these poetry miscellany and collections there is a valuable handwritten miscellany that has been estimated to have been recorded between the tenth and eleventh centuries and its handwritten copy is kept in the library of the majlis of Islamic council under number 156. This manuscript has been written by an unknown scribe and has been probably recorded based on the manuscript belonging to the sixth or seventh hijri century. The most prominent trait of this manuscript is the essence of the poems written by the unknown poets, the recent poems by the famous poets, and the attribution of some poems to the other poets, and some affidavits. The present article introduces this copy fully and tries to unravel its literary and research values for those who are interested in the poetry specially the Farsi poetry in the 5th, 1th, and 7th centuries. Manuscript profile -
Open Access Article
722 - Presenting a team entrepreneurial passion model in accelerators using a grounded theory qualitative method
elham irannejadparizi kambiz talebi jahangir yadollahi farsi hamideh reshadatjooPassion and motivation among entrepreneurial teams can have a significant impact on the performance of businesses. Given the team-based nature of entrepreneurial activities in our modern age, the study of the environment’s role in a team’s emotions and passi MorePassion and motivation among entrepreneurial teams can have a significant impact on the performance of businesses. Given the team-based nature of entrepreneurial activities in our modern age, the study of the environment’s role in a team’s emotions and passion in centers providing services to start-up teams has found particular significance. The present study was conducted to present an entrepreneurial passion model in teams based on accelerators. The present study was conducted within the framework of a qualitative approach, using grounded theory research methodology (the Strauss and Corbin approach). Semi-structured interviews were used to collect data and the theoretical sampling was conducted purposively, where theoretical saturation was reached after 13 interviews. The results of the study were drawn into a paradigm model including team entrepreneurial passion as the main subject and causal circumstances (financial services, locale, training, and mentor), background (team entrepreneurial passion focal point), intervening factors (entrepreneurial orientation and self-efficacy), strategies (external strategies and internal strategies), and consequences (repeatability and scalability of the business model, market development and …).Services provided in accelerator centers providing support for entrepreneur teams have a remarkable impact on the entrepreneurial passion of start-up teams, that can have a great impact on team performance . Manuscript profile -
Open Access Article
723 - Presenting the corporate entrepreneurship process model in businesses active in the Iranian cellulose industry
reza mohammad kazemi kamran NaiknamianPresenting the corporate entrepreneurship process model in businesses active in the Iranian cellulose industryAbstract:Translation types Text translation Source text 1112 / 5000 Translation results The present study aims to provide a corporate entrepreneurship process m MorePresenting the corporate entrepreneurship process model in businesses active in the Iranian cellulose industryAbstract:Translation types Text translation Source text 1112 / 5000 Translation results The present study aims to provide a corporate entrepreneurship process model in businesses active in the Iranian cellulose industry in terms of explanatory purpose in terms of practical results and a mixed approach. Data were collected through a library study of available resources and semi-structured interviews with 20 Iranian cellulose industry experts who were purposefully selected and using the data theory method and three-step coding (re-axis -Optional) 259 open codes, 24 central codes and 5 selected codes were counted. The results showed that the central phenomenon (corporate entrepreneurship process) includes 9 steps of strategy, idea generation, market analysis, idea analysis, idea selection, idea modification, concept and construction, marketing and commercialization, and its causal preconditions, including Business competencies are human resource prerequisites, managerial competencies, market information drivers. Contextual factors including political-legal context, social context, and intervening factors including economic contexts and technical contexts were considered to be effective on strategies (human resource strategies, marketing strategies, knowledge strategies, network strategies), and the consequences of these strategies. Manuscript profile -
Open Access Article
724 - The effect of customers' perception of celebrity online branding on customers' purchase intention with the moderating role of perceived product quality
Arash Beigi Zahra DashtlaaliIn the era of competition, one of the marketing communication strategies is to use celebrity endorsements on social networks. The present study was conducted with the aim of investigating the effect of customers' perception of online branding of celebrities on customers MoreIn the era of competition, one of the marketing communication strategies is to use celebrity endorsements on social networks. The present study was conducted with the aim of investigating the effect of customers' perception of online branding of celebrities on customers' purchase intention with the role of moderator of perceived product quality. This research is applied in terms of purpose and descriptive in nature, survey. The statistical population of the study was Iranian users of the Instagram social network in the whole country, and 384 people were selected in a non-random way through Cochran's formula. The main tool of data collection was a questionnaire, and its validity was confirmed by using scientific components by experts, and its reliability was confirmed by using Cronbach's alpha test. The findings showed: customers' perception of online branding of famous people has an effect on customers' purchase intention with the moderating role of perceived product quality. The effect of virtual interaction, ideal match and actual match with oneself on customers' purchase intention was confirmed. Also, perceived product quality moderates the effect of virtual interaction, ideal self-congruity and actual self-congruity on customers' purchase intention. Manuscript profile -
Open Access Article
725 - Intelligent Power Control of Green Building-Integrated of Fuel Cell and Plug-in Electric Vehicle in Smart Distribution Systems
Iman Ghiasi Masoud Golkar Amin Hajizadeh -
Open Access Article
726 - Application Flatness Technique for Intelligent Control of a New Electric Energy Source
Mohsen Radan -
Open Access Article
727 - Modeling and Improvement of Function of Solar Resources using Comparative Multipurpose Algorithm of PSO
Shahin Bazeghi Shahram Javadi Arsalan Hekmati -
Open Access Article
728 - Energy Management in Photovoltaic Based Micro-Grid Systems
Mojtaba Jamiati -
Open Access Article
729 - Modeling of Maximum Solar Power Tracking by Genetic Algorithm Method
Mojtaba Jamiati -
Open Access Article
730 - Design of Fault-Tolerant XOR/XNOR Gate Using Fault-Tolerant NNI Gate
Fatemeh Kiayi Behnaz Gharekhanlou Alireza Kashaninya -
Open Access Article
731 - A 27-31 GHz CMOS LNA for 5G Application via Improved Noise Cancellation Technique and Gain Boosting
Seyed Alborz Hosseini Mahmoud Mohammad Taheri Ramin Khosravi Gholamreza Moradi -
Open Access Article
732 - Design and Implementation of Tile-shaped Fault-tolerant XOR/XNOR Gates Based on Intercellular Interactions
Fatemeh Kiayi Behnaz Gharekhanlou Alireza Kashaninya -
Open Access Article
733 - Removing High Density Impulse Noise Via a Novel Two Phase Method Using Fuzzy Cellular Automata
Mohammad Mehdi Piroozmandan Fardad Farokhi Kaveh Kangarloo -
Open Access Article
734 - Investigation of Parameters Affecting the Geometry of Red Blood Cell Using Low-Dimension Model in Dissipative Particle Dynamics
Somaye Yaghoubi -
Open Access Article
735 - A Smart Four-Input Minority Gate Based on QCA Technology
Samaneh-Sadat Hashemipour Keivan Navi -
Open Access Article
736 - Genetic algorithm for Echo cancelling
Alireza rezaee -
Open Access Article
737 - Investigating the role of empowering police force employees in organizational excellence
Amir Masoomy mhrdad mohammadian nasrin khodabakhshiAttention to organizational excellence and staff empowerment has increased due to accelerating developments and competition for greater success among military organizations. The aim of this study was to investigate the role of police force employees staff empowerment in MoreAttention to organizational excellence and staff empowerment has increased due to accelerating developments and competition for greater success among military organizations. The aim of this study was to investigate the role of police force employees staff empowerment in organizational excellence by survey method. The statistical population included all police force employees who were serving in Ardabil province in 1400. 320 questionnaires were distributed using multi-stage cluster sampling method. Validity and reliability of the questionnaire were calculated using content validity tests, mean variance extracted, composite reliability and Cronbach's alpha, using Smart Pls software, which confirmed the obtained coefficients, validity and reliability of the assessment tool. It was determined by analyzing the data; The level of organizational excellence and employee empowerment is high and employee empowerment explains 64% of changes in organizational excellence. The results of hypothesis analysis showed that perceived organizational support, management style, work experience and cultural and economic capital have a moderating role in the relationship between employee empowerment and organizational excellence of police force employees. Criteria Z and R2 also showed that the experimental structural model has a suitable fit. Manuscript profile -
Open Access Article
738 - The role of mobile-based virtual networks in reproducing the five dimensions of religious culture among Iranian youth
Yavar Alipoor mollabashi ali jafari shahnaz HashemiThe aim of the present study was to investigate the role of mobile networks based on mobile phones in reproducing the dimensions of religious culture among the young people in Iran. In other words, the main issue of the article is the role of social networks on cultural MoreThe aim of the present study was to investigate the role of mobile networks based on mobile phones in reproducing the dimensions of religious culture among the young people in Iran. In other words, the main issue of the article is the role of social networks on cultural changes and orientations and the reproduction of the dimensions of religious culture among Iranian youth. To do this, Based on Gerbner's views, media social theories were selected as a theoretical framework. The type of research is applied in terms of purpose and survey in terms of implementation. The population of the study was 18-29 year old youths in Tehran, Ardabil, Gorgan, Shiraz and Kermanshah in 2019. The sampling method was cluster sampling and the sample number was 384. To analyze the data, using Amos software, Path analysis and factor analysis were used. The results showed that the use of mobile-based virtual networks in religious insight, duration of membership in mobile-based networks in religious orientation, participation and activation of mobile-based virtual networks in religious value, religious behavior and religious identity are significantly affected among Iranian youth. Therefore, mobile-based virtual networks play an important role in reproducing religious culture among Iranian youths. In other words, taken from Planting theories and social theories it can be claimed that the more the amount of use and duration of membership in social networks, the more the probability of effect on the user. Manuscript profile -
Open Access Article
739 - The Effects of the Cancellation of a Contract on the Alienable Possession from the Standpoints of Iranian Law and Imamieh Jurisprudence
Hossein Jafari Samet Mahshid Sadat Tabaei Javad Niknejad,Although, the contracts are binding, but in some occasions, due to some reasons, one of the parties may decide to cancel a contract. A cancellation of contract results in termination of a contract and its effects. The important point regarding the cancellation of a cont MoreAlthough, the contracts are binding, but in some occasions, due to some reasons, one of the parties may decide to cancel a contract. A cancellation of contract results in termination of a contract and its effects. The important point regarding the cancellation of a contract is that, if, after concluding a contract and before cancellation, a transferee take the possession of an object of transaction as a transferor, for example, if they sell an object of transaction to a third party, what may be the effects of cancellation of the contract on the alienable possession? Dose it results also in cancellation of the selling, or, principally, the transferee might not to do the transferring acts? And, as the consequence, the transaction is invalid? There is some disagreement among the lawyers and jurisprudents on the interpretations of Iranian law and Imamieh jurisprudence. Although, there is less disagreement on the interpretations of legal cancellations of contracts, and, principally, the jurisprudents and lawyers both believe that this cancellation has no effects on the validity of the selling. Then, the transferee should return the object of transaction to the transferor. But, on the contractual powers, including option of condition, there is disagreement between the lawyers and the jurisprudents. Some of them believe that in those options of conditions there is an implicit condition that one against whom an option is stipulated may not take possession of an object, including the possession of the object of a transaction, by violation of conditions, otherwise, the transaction is invalid. Some other believe that, regarding the mentioned options of conditions, unless it is expressly stipulated otherwise, one against whom an option is stipulated may not take possession of an object of transaction. Manuscript profile -
Open Access Article
740 - Technical Analysis indicators calibration using Cellular Automaton Algorithm for use in high-frequency trading
alireza Ahmadi Ali Paytakhti Oskooi Siroos Fakhimi Azar Younes Badavar NahandiThe present study was conducted with the aim of localizing technical analysis indicators in the Tehran Stock Exchange in order to predict stock price movement trends in implementing high frequency trading by the momentum method. In this study, calibration of exponential MoreThe present study was conducted with the aim of localizing technical analysis indicators in the Tehran Stock Exchange in order to predict stock price movement trends in implementing high frequency trading by the momentum method. In this study, calibration of exponential moving average, Bollinger Bands, Relative Strength Index (RSI), degree of difference, stochastic indicator and cash flow index was performed using cellular automata algorithm. The statistical population of this research consists of data obtained from transactions performed in the Tehran Stock Exchange during a three-year period from 7/23/2019 to 7/22/2019. According to the obtained results, there is a need to change the periodicity of the indicators calculations, so that the indicators of exponential moving average, Bollinger Bands, relative strength index, degree of difference, the stochastic indicator, the cash flow index have been changed from 14 to 2 days, 20 to 2 days, 14 to 13 days, 12 to 2 days, 14 to 4 days, and 14 to 20 days, respectively. As a result of the changes made, the increases in predictive power of the above indicators were achieved up to 1.35%, 36.90%, 1.89%, 30.52%, 64.20%, 0.24%, respectively. Manuscript profile -
Open Access Article
741 - The effect of financial friction on the speed of stock price convergence
Sepideh Rajizadeh Amirhossein Taebi Noghondari Hadis ZeinaliAny factor that reduces the positive effects of rising stock prices creates a kind of financial friction for stocks. The role of financial friction in justifying the slowdown in stock price convergence is significant because it interferes with financial transactions and MoreAny factor that reduces the positive effects of rising stock prices creates a kind of financial friction for stocks. The role of financial friction in justifying the slowdown in stock price convergence is significant because it interferes with financial transactions and stock pricing, and investors are unable to completely reduce firm-specific risk through diversification if there is financial friction. The above issue is one of the new issues in the capital market that due to the novelty of the areas of financial friction and the speed of stock price convergence, little research has been done nationally and internationally; Less attention has been paid to this dimension of research variables. Therefore, the purpose of this study is to investigate the effect of financial friction on the speed of stock price convergence. The data of this study consisting of 89 companies listed on the Tehran Stock Exchange during the years 2010 to 2019 were reviewed. To test the research hypotheses, the generalized least squares regression model has been used. The results of the study indicate that there is a negative and significant relationship between financial friction and the speed of stock price convergence. Manuscript profile -
Open Access Article
742 - Strategy of Data Foundation Theory Method with Coding Method and Paradigm Model of Strauss and Corbin to Provide a Model for Accelerating the Cooperation of Macro-Corporate with Micro-Businesses
Vahid Bekhradi NasabMicro-Businesses have resources constraints to start and develop a business and need access to resources beyond the business boundaries through relationships with Macro-Corporate. Macro-Corporate face a lack of flexibility despite access to financial resources. The solu MoreMicro-Businesses have resources constraints to start and develop a business and need access to resources beyond the business boundaries through relationships with Macro-Corporate. Macro-Corporate face a lack of flexibility despite access to financial resources. The solution to this problem is to use the capacity of development intermediary organizations. Accordingly, the present study has presented a model for accelerating the cooperation of Macro-Corporate with Micro-Businesses. The research method is based on the strategy of data foundation theory method with coding method and paradigm model of strauss and corbin. The statistical population of the research is business development experts and the sample of targeted research by snowball method includes 12managers, experts, professors aware of business development in the period of2021. The data collection tool was a structured interview and the focus group continued with the subject matter experts until the theoretical level was reached. The results showed that the basic category of cooperation in the pre-acceleration phase, the agile environment of cooperation in the acceleration phase and the gradual partnership of cooperation in the post-acceleration phase on the cooperation of Macro-Corporate with businesses. Wisdom has a significant effect. Manuscript profile -
Open Access Article
743 - Investigation the Impact of Organizational Excellence Model on Effective Marketing in Azad University
Nassim Heidari Vahidreza MirabiAbstractToday, organizations are seriously facing the change of business environment from a supportive environment to competition and widespread growth in the country's economy. In this research, the effect of organizational excellence on marketing in the field of Azad MoreAbstractToday, organizations are seriously facing the change of business environment from a supportive environment to competition and widespread growth in the country's economy. In this research, the effect of organizational excellence on marketing in the field of Azad University was investigated using structural equations and pls software. The statistical population of this research is all Islamic Azad universities in the whole country. In order to determine the sample size, 350 people were selected from Cochran's formula. The results showed that the components of the organizational excellence model in Islamic Azad University include strategy, leadership, partnerships and resources, processes, products, services, employees, community results, employee results, key results, customer results. The components of effective marketing in Islamic Azad University have included social marketing, ethical marketing, strategy-oriented marketing, internal marketing, green marketing, lean marketing, and innovative marketing. Based on the results, the organizational excellence model is effective on effective marketing. And of the marketing components, green marketing alone is not the key.Keywords: Organizational Effectiveness, Organizational Excellence Model, Effective Marketing Manuscript profile -
Open Access Article
744 - Investigating the Relationship between Transformational Leadership and Psychological Capital with Organizational Excellence (Case Study: Tehran Region 1 Education Organization)
Parastoo Khosravi Setareh Sepehri Fatemeh HamidifarThe purpose of this study was to investigate the relationship between transformational leadership and psychological capital with organizational excellence of the Education Organization of Region 1 of Tehran. This applied research was a field data collection method and i MoreThe purpose of this study was to investigate the relationship between transformational leadership and psychological capital with organizational excellence of the Education Organization of Region 1 of Tehran. This applied research was a field data collection method and in terms of implementation method was descriptive-correlational. The statistical population consisted of 600 employees of Tehran Region 1 Education Organization, who were selected as the sample size using Krejcie and Morgan table and relative stratified random sampling method. Data collection tools were standard questionnaires of transformational leadership Bass and Olivier (2000), Lutans psychological capital (2007), Deming organizational excellence (1979). The validity of these questionnaires was confirmed by experts and the reliability was calculated using Cronbach's alpha coefficient (transformational leadership equal to 0.92 psychological capital equal to 0.91 organizational excellence equal to 0.89 percent). Descriptive (frequency and percentage calculation) and inferential (Kolmogorov-Smirnov, Pearson correlation coefficient and multivariate regression) were used to analyze the data using Spss26 software. The results showed that there is a relationship between transformational leadership and psychological capital with the organizational excellence of education. It also showed between the dimensions of transformational leadership (individual consideration, persuasion, inspirational motivation and ideal influence) with organizational excellence and between the dimensions of psychological capital (hope, resilience, optimism and Self-efficacy) is related to organizational excellence. Manuscript profile -
Open Access Article
745 - Identifying the Main and Sub- Categories of a Business Model Based on Training and Developing Human Resources at the Agricultural Bank of Khuzestan Province
, Aliakbar Karimpour, Leila Bahmaee Mohammad Hosseinpour Mehdi BasiratThis study aimed to identify the main and sub-components of a business model based on training and developing human resources at the Agricultural Bank of Khuzestan province. The research utilized a qualitative approach involving interviews with 15 experts and managers a MoreThis study aimed to identify the main and sub-components of a business model based on training and developing human resources at the Agricultural Bank of Khuzestan province. The research utilized a qualitative approach involving interviews with 15 experts and managers at the Bank. Data was collected through in-depth, semi-structured interviews. Qualitative content analysis using the interview editing method was conducted to extract key concepts and categories from the interviews. The ISM method was also used to analyze relationships between components. The statistical population in the qualitative and ISM sections included 15 experts with relevant scientific background and experience working in the Bank of Agriculture, who were selected using a purposeful and non-probability sampling method. In-depth interviews were conducted with them, which were semi-structured. The first step of the current study was to identify the main and sub-categories of the research using the qualitative content analysis method (interview editing approach, summarizing them, and interpreting concepts and words). MAXQDA software was used for qualitative analysis. By extracting the main and sub-categories of the research using the results of qualitative content analysis and the ISM method, the final model was presented. In total, the pattern obtained consists of 12 main categories and 60 sub-categories. Leadership strategy was identified as the most basic component of business with the approach of human excellence. Manuscript profile -
Open Access Article
746 - An implicit finite difference scheme for analyzing the effect of body acceleration on pulsatile blood flow through a stenosed artery
A. Haghighi N. Aliashrafi N. Asghary -
Open Access Article
747 - Structure of an Adaptive with Memory Method with Efficiency Index 2
Vali Torkashvand -
Open Access Article
748 - An Efficient Method to Solve the Mathematical Model of HIV Infection for CD8+ T-Cells
Samad Noeiaghdam Emran Khoshrouye Ghiasi -
Open Access Article
749 - OPTIMUM GENERALIZED COMPOUND LINEAR PLAN FOR MULTIPLE-STEP STEP-STRESS ACCELERATED LIFE TESTS
Navin Chandra Mashroor Ahmad Kha -
Open Access Article
750 - A NEW TWO STEP CLASS OF METHODS WITH MEMORY FOR SOLVING NONLINEAR EQUATIONS WITH HIGH EFFICIENCY INDEX
Taher Lotfi Paria Assari -
Open Access Article
751 - Modeling charge carrier densities in solid-state nanostructured dye-sensitized solar cells
ُTahmineh Jalali Morteza Sadaghi Shahriar OsfouriDye-sensitized solar cells (DSSCs) are a newer generation of solar cells that, although they have lower efficiency compared to silicon-based solar cells, have a high potential for improved efficiency. Due to their better cost-effectiveness, they can replace silicon-base MoreDye-sensitized solar cells (DSSCs) are a newer generation of solar cells that, although they have lower efficiency compared to silicon-based solar cells, have a high potential for improved efficiency. Due to their better cost-effectiveness, they can replace silicon-based solar cells in the market if their efficiency and stability increase. The design and development of DSSCs have involved not only experimental and laboratory work but also numerical modeling. The aim of this work is to design and numerically model dye-sensitized solar cells based on a nanostructured semiconductor layer with a wide bandgap (titanium dioxide) and zinc oxide as the electron transporter, N719 dye as the absorber layer, and PEDOT:PSS and P3HT as hole transport materials. In this research, the advanced software CAMSOL with extensive capabilities is used for the design of dye-sensitized solar cells, and the current-voltage characteristics and optical absorption of the cell are calculated, which are in agreement with experimental data. Manuscript profile -
Open Access Article
752 - Evaluation of Cell membrane Instability of Oily Sunflower Varieties under Water Deficit and Salicylic Acid Application
Mohammad Sibi Mohammad Mirzakhani Masoud Gomarian Hesamedin YaqobiExperimental treatments comprised of water stress as a major factor in three levels including I0 = irrigation water requirement of crop (control), I1= 80 percent of the amount of irrigation water requirements of crop, I2= 60 percent of the amount of irrigation water req MoreExperimental treatments comprised of water stress as a major factor in three levels including I0 = irrigation water requirement of crop (control), I1= 80 percent of the amount of irrigation water requirements of crop, I2= 60 percent of the amount of irrigation water requirements of crop in the main plots and different varieties of sunflower including V1= Azargol, V2= Alstar, V3= Ariflor and two levels of salicylic acid containing SA0= without salicylic acid and SA1= with salicylic acid (sprayed) as a minor factor in a factorial combination of sub-plots. The results showed the very significant effect (p<0.01) of different levels of water stress and varieties of sunflower on stem diameter, number of leaves, number of hollow grains, biological yield, ion leakage of cell (cell membrane instability), leaf water content, initial water content and ultimate water of leaf. Salicylic acid also had significant effect on number of leaves, cell ion leakage (cell membrane instability), leaf water content, initial water content and leaf ultimate water at a level of statistical significance, whereas stem diameter, number of hollow grains and biological yield did not affected by salicylic acid. Thus, ion leakage cell increased with increasing intensity of water deficit, therefore the highest average of ion leakage (2854.9 μs) obtained from extreme stress (60 percent of the amount of irrigation water requirements of crop). Manuscript profile -
Open Access Article
753 - بررسیفاکتورهایخونیوایمنیدربچهماهیاناسکار(Astronotus ocellatus)تغذیه-شدهباناپلیآرتمیایغنیسازیشده باپربیوتیکمانانالیگوساکاریدوپربیوتیکدیوارهی-سلولیمخمرنانوایی (Saccharomyces cerevisiae)
فائزه سمیع املشی عباسعلی زمینی -
Open Access Article
754 - The Effect of Low Temperatures on Domestic and Wild Pistachio Rootstocks and Interspecific Hybrids Based on Physio-biochemical Indices
Maryam Afrousheh Amir Mohammadi Hojat Hasheminasab Ali Taj Abadi Pour Hasan Arab Alireaz Dabestani -
Open Access Article
755 - Effect of Sulfur on Toxigenic Aspergillus flavus In Vitro
Arezou Kazemi Ebrahim Sedaghati Seyed Reza Fani Mohammad Moradi Marieh Nadi -
Open Access Article
756 - Examination of the Effect of Methylcellulose on the Reduction of Aflatoxin Production during Pistachio Storage
Zeinab Moslehi maryam Araghi Marzie Moslehi -
Open Access Article
757 - Growth Inhibition of Aspergillus flavus Isolated from Pistachio by Secondary Metabolites
s. Alizadeh-Salteh -
Open Access Article
758 - Inhibition of Trichoderma Species from Growth and Zoospore Production of Phytophthora Drechsleri and Their Effects on Hydrolytic Enzymes
S. Jamali N. Panjehkeh A.H. Mohammadi -
Open Access Article
759 - Microwave induced combustion Synthesis of Nano- Codoped Ceria and their electrical properties
Ali Ainirad -
Open Access Article
760 - Synthesis of Nano-Ca doped Ceria by combustion method and investigating of effective factors on process
Ali Ainirad -
Open Access Article
761 - A two-dimensional numerical model of a planar solid oxide fuel cell
Norouz Mohammad Nouri Amin Mirahmadi Majid Kamvar -
Open Access Article
762 - The Effect of Potassium and Zinc Application on Resistant to Lodging of Two Wheat Cultivars
MARYAM ZAHERI ALI GHOLAMI HABIBOLLAH NADIAN EBRAHIM PANAHPOUR -
Open Access Article
763 - آدنوم غده سباسه در یک سگ ماده اورایوهیسترکتومی شده نژاد مخلوط
عبدالرسول نامجو ثنا سادات افضلنئوپلاسمهای غدد سباسئوس بهعنوان یکی از نئوپلاسمهای پوستی در سگ هستند. یک قلاده سگ ماده اواریوهیسترکتومی شده 5 ساله، نژاد تریر آمیخته با مشخصات مورفولوژیک تودهی زیر پوستی محصور، مدور، منفرد به رنگ سفید مایل به زرد، قوام نسبتا نرم و با قطر تقریبی 9 میلی متر در حد واسط Moreنئوپلاسمهای غدد سباسئوس بهعنوان یکی از نئوپلاسمهای پوستی در سگ هستند. یک قلاده سگ ماده اواریوهیسترکتومی شده 5 ساله، نژاد تریر آمیخته با مشخصات مورفولوژیک تودهی زیر پوستی محصور، مدور، منفرد به رنگ سفید مایل به زرد، قوام نسبتا نرم و با قطر تقریبی 9 میلی متر در حد واسط سمت راست منطقه پیشانی و کارواریوم با موریختگی خفیف به کلینیک دانشکده دامپزشکی دانشگاه آزاد اسلامی واحد شهرکرد ارجاع داده شد. سپس به روش جراحی بصورت کامل جهت تشخیص آسیب شناسی برداشته و در داخل فرمالین بافر 10 درصد قرار گرفت. پس از مراحل آب گیری، شفاف سازی و آغشتگی با پارافین، به روش رنگ آمیزی با هماتوکسیلین و ائوزین رنگ آمیزی شد. مشخصات میکروسکوپیک توده توموری دو نوع سلول مختلف شامل سلولهای غدد سباسوس بالغ با سیتوپلاسم واکوئله و هسته کوچک هیپرکروم و چند ردیف سلولهای بازالوئید سل در پیرامون لبولهای سباسئوس بدون تقسیم میتوز که با فولیکول های مو ارتباط نداشت را نشان داد .در داخل چند فولیکول مقاطعی از اجزاء میانی بدن دمودکس مشاهده شد. گزارش ما یک نمونه منحصر به فرد از سباسئوس آدنوما با آلودگی فولیکولهای مو با مایت دمودکس در یک سگ ماده عقیم شده است. Manuscript profile -
Open Access Article
764 - Investigating the effect of mesenchymal stem cells on airway hyper-responsiveness in asthma
Kambiz Moghaddasi Saeed Hesaraki Farnoosh Arfaee Seyyed Shamsadin AthariAsthma is a lung disease characterized by eosinophilic inflammation, mucus secretion, airway hyper-responsiveness (AHR), and airway obstruction. AHR is a crucial factor in asthma. Mesenchymal stem cells (MSCs) have a regulatory effect on the immune response and may be u MoreAsthma is a lung disease characterized by eosinophilic inflammation, mucus secretion, airway hyper-responsiveness (AHR), and airway obstruction. AHR is a crucial factor in asthma. Mesenchymal stem cells (MSCs) have a regulatory effect on the immune response and may be useful in treating asthma. MSCs have low immunogenicity and are considered safe for application. Additionally, a study was conducted to investigate the effect of MSCs on controlling AHR in an asthma model. MSCs were isolated and used to treat asthmatic male BALB/c mice. To produce an animal model of asthma, the mice were sensitized and challenged with OVA. On days 30 and 40, to measure AHR, a Methacholine challenge test was performed to determine the Penh value. AHR was recorded and analyzed. Treatment of asthmatic mice with MSCs resulted in a significant difference (p<0.05) in controlling AHR during the MCh challenge test. MSCs are almost non-immunogenic and can be used to treat asthma and control AHR. The use of MSCs as an anti-asthma treatment presents a new and applicable strategy for controlling AHR in asthma. Manuscript profile -
Open Access Article
765 - Cycocel application effect on barley cultivars (Hordeum vulgar L.) under different sowing date in Mazandaran province
Reza Rahimi Baladezaei Nabi alah Nemati Hamid reza Mobasser Salman DastanIn order to determination of Cycocel applicationeffect on barley cultivars (Hordeum vulgar L.) under different sowingdate, an experiment was carried out at split factorial in randomized completelyblock design with three replications at Mazandaran province in 2009-2010. MoreIn order to determination of Cycocel applicationeffect on barley cultivars (Hordeum vulgar L.) under different sowingdate, an experiment was carried out at split factorial in randomized completelyblock design with three replications at Mazandaran province in 2009-2010. Mainfactor was sowing dates in three levels including 7 and 26 November and 11December and sub factor was three varieties including Sahra, Productive and M12and cycocel rates in two levels including 0 and 2.8 lit/cycocel ha. Resultsshowed maximum and minimum of the spike per plant, grain per spike, and grainyield were obtained on 26 November and 11 December, respectively. Sahra and M12varieties had to most and least of the spike length, tiller per plant, spikeper plant, grain per spike, 1000 grain weight and grain yield, respectively.With application of the cycocel, decreased of the stem length, but increased ofthe spike length, tiller per plant, spike per plant, grain per spike, 1000 grainweight and grain yield. Maximum and minimum of the spike length, tiller perplant and grain yield were obtained in interaction of the 26 November × sahracultivar and 11 December × M12 varieties. Therefore sowing date ofthe 26 November, sahra variety and application of the 2.8 lit/cycocel habecause of the most of increased the yield components and due to grain yieldintroduced the best of treatment. Manuscript profile -
Open Access Article
766 - Effect of cycocel and Zinc Foliar Application on protein content and important elements and water use efficiency on Corn under water defcit condition
ehsan Abbaspour Jafar Masoud Sinaki Zarin taj Alipour Sakine Saeedi Sar To study the effect of water stress and the application of growth regulator (cycocel ) and Zinc spray on the protein rate, the major elements and some physical characteristics in corn (hybrid Ns540) .A split-split plot experime More To study the effect of water stress and the application of growth regulator (cycocel ) and Zinc spray on the protein rate, the major elements and some physical characteristics in corn (hybrid Ns540) .A split-split plot experimental with three replications in a randomized complete block design in Semnan Agricultural Research Station in 2010 in was run. The main factor included three levels of irrigation (irrigation complete, disconnect the water at 71 BBCH and 61 BBCH) in main plots and taking cycocel three levels (without taking cycocel consumption cycocel 1500, and 3000 parts per million) in the subplots and spraying zinc sulfate in three levels (no foliar applications, foliar applications of zinc sulfate at 3 and 5kg per thousands) as the subplots - are considered minor. Analysis of variance showed that the impact of cut irrigation on protein content, major elements such as phosphorus, potash, zinc, copper and iron, and water use efficiency is significantly. With the increased tension of the grain protein content and concentration of phosphorus, potash, zinc, iron and copper were reduced and increased water use efficiency. That results showed, taking cycocel, potash and phosphor decreased and other indicators increased. Zinc spraying the exception of the iron (Fe) increase in other indicators. the Correlation between Important elements and components of protein content and water use efficiency showed that Positive and significant correlation between water use efficiency and a high copper content of 0.474 percent is established And grain protein correlated with leaf phosphorus content of 0.522 percent. The findings can be to corn-growing of Semnan and similar region drought conditions that prohibit the use of certain materials and components that manufacturers offer to achieve good economic performance and quality. Manuscript profile -
Open Access Article
767 - Effect of plant growth regulator Cycocel and different levels of nitrogen fertilizer on some growth characteristics and yield of barley
A. Afkari M. AbbasiThe Effect of plant growth regulator Cycocel and different levels of nitrogen fertilizer on some growth characteristics and yield of barley, factorial experiment was conducted based on randomized complete block design with four replications in Research Station of the fa MoreThe Effect of plant growth regulator Cycocel and different levels of nitrogen fertilizer on some growth characteristics and yield of barley, factorial experiment was conducted based on randomized complete block design with four replications in Research Station of the faculty of Agriculture, Islamic Azad University Branch Ardabil in 2015. Treatments the experiment consisted CCC concentration (zero, 500, 1,000 and 1,500 mg per hectar) and three levels of nitrogen (50, 100 and 150 kg per hectar) was applied in the form of urea on Makuyi spring barley cultivars.The results of this study showed that the concentrations of various nitrogen and cycocel on the number of fertile tillers, spike length and harvest index at 5% and the number of spikes per square meter, number of seeds per plant, grain weight, height plant, seed yield and biological yield were significant at the 1% level. The interaction of different concentrations of nitrogen and cycocel on the number of spikes per square meter, grain yield and biological yield was significant at 1%. In this experiment results mean comparisons showed that the highest number of fertile tillers (1/5), spike length (9/6cm), grain yield (3687kg/ha) and thousand grain weight (34/7 gr) respectively, application CCC (1500 mg/ha). The results of interaction between nitrogen fertilizer and different concentrations of cycele showed that the highest number of fertile tillers (1.8), number of spikes per square meter (383.5), grain yield (3808 kg/ha) and biological yield (3808 kg /ha) (17795/2 kg/ha) using 150 kg of nitrogen per hectare with 1500 mg/ha cycocel was obtained. Manuscript profile -
Open Access Article
768 - Effect of cycocel and micronutrients on antioxidants rates as indices of drought resistance of rapeseed
S. Hamrahi D. Habibi H. Madani M. Mashhadi Akbar BoojarEffect of micronutrients and cycocel in drought tolerance of rapeseed was determined by using split factorial design on RCBD with 12 treatments and 4 replications. Experiment was done in research farm of Arak Islamic Azad University during 2007-2008. The treatments cons MoreEffect of micronutrients and cycocel in drought tolerance of rapeseed was determined by using split factorial design on RCBD with 12 treatments and 4 replications. Experiment was done in research farm of Arak Islamic Azad University during 2007-2008. The treatments considened by irrigation as main factor in 2 levels (normal and drought), 3 levels of micronutrients (0, 1, 1.5 lit/ha) and 2 levels cycocel (0, 1.5lit/ha) as sub factors. 22 variables were determined which were included plant height, full and empty pod number per plant, pod weight per plant, pod number per stem and sub-branch, seed number per pod, stem diameter, seed weight per plant, 1000 seed weight, seed yield, total dry weight, harvest index, relative water content, ionic leakage, SOD, CAT, GPX, MDA , di-Tyro, 8-oh-dg. Result indicated high significant increase in antioxidant enzymes rate in drought condition which means the defensive mechanism of plant in drought condition. Micronutrients caused high significant difference in antioxidant enzymes rate between drought and normal condition so that caused drought tolerance in plant by decreasing the pressure of tension. In addition cycocel consuming resulted in high significant plant height decrease and stem diameter increase due to drought tolerance. Manuscript profile -
Open Access Article
769 - The effect of water deficit stress and manure on quantitative and qualitative yield and some characteristics of physiological (Plantago Ovata Forssk.)
B. Afsharmanesh Gh. Afsharmanesh M. A. Vakili ShahrbabakiIn order to study effect of water deficit stress and manure onon quantitative and qualitative yield and some characteristics of physiologicalof plantago ovate a pot experiment was performed at the greenhouse of Jiroft Islamic Azad University, Iran, in 2009. For this pur MoreIn order to study effect of water deficit stress and manure onon quantitative and qualitative yield and some characteristics of physiologicalof plantago ovate a pot experiment was performed at the greenhouse of Jiroft Islamic Azad University, Iran, in 2009. For this purpose split plot design based on complete randomized block with 3 replication was used. Irrigation treatments consist of 3 level: 75%FC (mild stress), 50%FC (Medium stress) and 25%FC (Sever Stress) were main factors and manure levels (0, 10, 20, 30 and 40 ton/ha) were selected as sub factors. The results showed effect of water deficit stress and manure and also interaction effect between two factor on seed yield were significant (P<5% and p<1%). Highest seed yield (232.3 kg/ha) obtained from mild stress with using 20 ton/ha manure. This two factor had no significant on mucilage. With increasing water deficit stress RWC was decreased. The maximum RWC obtained by using 40 ton/ha. Cell membrane stability was decreased under sever stress. Thus in Jiroft it's necessary for reach high yield in plantago ovata 20 t/ha manure. Manuscript profile -
Open Access Article
770 - Acute Genotoxic Effects of Effluent Water of Thermo-Power Plant “Kosova†In Tradescantia Pallida
I.R. Elezaj L.B. Millaku R.H. Imeri-Millaku Q.I. Selimi K. Rr. Letaj -
Open Access Article
771 - The Effect of Doxorubicin on Viability and Morphology of Human Embryonic Stem Cell-derived Cardiomyocytes
Marziyeh Shalchi Tousi Houri Sepehri -
Open Access Article
772 - The Effects of Environmental Pollution with Heavy Metals in Frequency of Micronuclei in Epithelial Buccal Cells of Human Population in Mitrovica
K. Letaj I. Elezaj Q. Selimi K. Kurteshi -
Open Access Article
773 - Influence of Arsenic (III), Cadmium (II), Chromium (VI), Mercury (II), and Lead (II) Ions on Human Triple Negative Breast Cancer (HCC1806) Cell Cytotoxicity and Cell Viability
Tsdale F. Mehari Checo J. Rorie Sherette S. Godfrey Radiah C. Minor Sayo O. Fakayode -
Open Access Article
774 - Histopathology of Inhalation of Industrial Bleach and Detergent Mixture on Epithelial Layer of Trachea in Mice
Gh. Vaezi F. Aliabadi Ab. shiravi M. pourkazem F. Toosi -
Open Access Article
775 - Molecularly Imprinted Polymers (MIP) for Selective Solid Phase Extraction of Celecoxib in Urine Samples Followed by High Performance Liquid Chromatography
Saeedeh Ansari Azam Ghorbani -
Open Access Article
776 - Cellular Toxicity of Multi-walled Carbon Nanotubes on Human Lung Cells
Nafiseh Nasirzadeh Yahya Rasoulzadeh Mansour Rezazadeh Azari Yousef Mohammadian -
Open Access Article
777 - The Study of Cytotoxicity of an Imidazolium Based Ionic Liquid on MCF-7 Cell Line
Elham Sajadiyeh Masoumeh Tabatabaee SayedMorteza Seifati Zohreh Derikvend -
Open Access Article
778 - The Study of Antioxidant and Cellular Toxicity Effects of Methanol, Ethyl Acetate, Aqueous and n-Hexane Extracts of Symphytum Kurdicum Plant
Shiva Khalil_moghaddam Atousa Aliahmadi Nastaran Jalilian Mohamad Aref Tabad -
Open Access Article
779 - Cytotoxicity Effect of Shigella flexneri Fraction on Breast Cancer Cell as a New Compound for Cancer Therapy
Mehdai Gudarzi Neda Soleimani Mahru Seyyed jafari olia -
Open Access Article
780 - Review of Recent Advances in Treatment of Celiac Disease Using Enzymatic Gluten Degradation
Mansooreh Hooshiyar Gholam Hossein Ebrahimi Pour Mohammad Rostami-Nejad Fahimeh Sadat Gholam-Mostafaei Kaveh Baghaei Alireza Emadi Vahid Khalaj -
Open Access Article
781 - Application of Modified Nanocellulose with 2-aminopyrimidine as a New Sorbent for Separation and Determination of Trace Amounts of Nickel Ions in Human Blood and Urine
Ali Mirabi -
Open Access Article
782 - The Influence of Fish Oil Supplementation on the Adverse Effects of Chemotherapy in Patients with Hepatocellular Carcinoma
Radhwan M. Hussein Adil Tawfeeq Mohammed Duha Mahdi Hussein Ali Abdulhussain Fadhil Muzahem Shallal Al-Ani Suhail Bayati Ahmed Abbas Sahib -
Open Access Article
783 - Synthesis and Cytotoxic Evaluation of 2-Pyrazoline Derivative on Leukemia Cancer Cell Line K562
Masoud Shaabanzadeh Maryam Bikhof Torbati -
Open Access Article
784 - Characterization of functionally graded hydroxyapatite/TiO2 multilayer coating on Ti-6Al-4V titanium alloy by electrophoretic deposition
محمد جعفر هادیان علیرضا عراقی طاهره طلایی مهسا ثانیSingle layer and functionally graded coatings of hydroxyapatite and TiO2 particles were deposited on Ti-6Al-4V titanium alloy substrate by electrophoretic deposition technique (EPD). The coatings chemical composition and morphology were investigated using energy dispers MoreSingle layer and functionally graded coatings of hydroxyapatite and TiO2 particles were deposited on Ti-6Al-4V titanium alloy substrate by electrophoretic deposition technique (EPD). The coatings chemical composition and morphology were investigated using energy dispersive X-ray spectroscopy (EDX), scanning electron microscope (SEM) and X-ray diffraction (XRD) methods. The results showed in HA/TiO2 functionally graded coating, the composition varied from inner layer to top layer as 100 %wt TiO2 to 100 %wt HA. To investigation biocompatibility of the coatings, the culture Wharton’s Mesenchymal Stem Cells was used. The results showed the HA/TiO2 functionally graded coating and HA single layer coating were more biocompatible in comparison to TiO2 single layer coating. The adhesion strengths of the coatings were measured by shear testing and the results showed that the HA/TiO2 functionally graded coating has more adhesion strength (~31 MPa) compare to HA single layer. Manuscript profile -
Open Access Article
785 - Effects of size and type of coating of iron powders and copper additive on the properties of hollow steel spheres
Hamid Sazegaran علیرضا کیانی رشیدMetal hollow spheres are successfully used for manufacturing of cells and porosities in the cellular structures and metallic foams that important production methods of them are based on powder metallurgy. In this paper, steel hollow spheres are produced by powder metall MoreMetal hollow spheres are successfully used for manufacturing of cells and porosities in the cellular structures and metallic foams that important production methods of them are based on powder metallurgy. In this paper, steel hollow spheres are produced by powder metallurgy method and polystyrene beads are used as substrate materials. Polystyrene beads are separated from a polystyrene block and sorted by sieving. Then, mixture of sodium silicate, as binder, and iron powder was sprayed on prepared beads. After drying, a thin layer of iron powder was covered polystyrene beads. Finally, two different heat treatment processes to produce high strength steel hollow spheres was undertaken. These processes are involving the pyrolysis of polystyrene beads and sintering process. For shell thickness measurements, determination of porosity content and flaws evaluation, shell section of hollow spheres were studied by optical microscopy. Produced hollow steel spheres are nearly uniform thickness in shell. Size of iron powder particles, cupper content and type of coating of iron powder are strongly affected on shell thickness, porosity percent and shell flaws. Manuscript profile -
Open Access Article
786 - An investigation of the effect of sintering condition on the strength of Ni foam produced by electroplating method
Akram Salehi Faeze Barzgar احمد مولودیMetal foams are a relatively new class of materials. They provide a high energy absorption ability, large surface to volume ratio, and a high stiffness to weight ratio because of the existence of porosity in their structure. One of the most applicable metal foams is nic MoreMetal foams are a relatively new class of materials. They provide a high energy absorption ability, large surface to volume ratio, and a high stiffness to weight ratio because of the existence of porosity in their structure. One of the most applicable metal foams is nickel foam used as catalysts, filters, and silencers in different industries. In this work, Ni foam has been prepared by electrodeposition technique on a polyurethane sponge substrate. The produced foams were sintered at 600℃ and 1000℃ in the neutral atmosphere to eliminate organic substrate and increase their ductility. EDX analysis showed that carbon atoms have diffused into Ni deposition during sintering at 600 ℃, and also the samples sintered at 1000 ℃ have oxidized. The pressure tests indicated that the samples were ductile after the sintering process. By increasing ductility, plateau strength will reduce from 4.79 MPa to 3.6 MPa and 1.65 MPa for the samples sintered at 600℃ and 1000℃, respectively. Obtained results showed that heat treatments didn’t have any effects on the densification strain, but energy absorption reduced from 1.51 MJ/cm2 to 1.21 MJ/cm2 and 0.55 MJ/cm2 for the sintered samples at 600℃ and 1000℃, respectively. Manuscript profile -
Open Access Article
787 - An investigation on the behavior of manganese cobaltite spinel oxide as the SOFC interconnect coating materials
Pooria Lesani Alireza Babaei Abolghasem AtaieIn this study, Manganese cobaltite (MnCo2O4) spinel powders were synthesized by co-precipitation method. X ray diffraction (XRD) patterns show that the spinel phase was formed at around 350°C. Formation of spinel phase was further completed by increasing temperature MoreIn this study, Manganese cobaltite (MnCo2O4) spinel powders were synthesized by co-precipitation method. X ray diffraction (XRD) patterns show that the spinel phase was formed at around 350°C. Formation of spinel phase was further completed by increasing temperature up to 1000°C. Additionally, XRD patterns prove that MnCo2O4 spinel material has been stable in this temperature range. Field emission scanning electron microscope observations show that plate like particles with an average diameter of 148 and thickness of 18 nm was converted to equiaxed particles with an average particle size of 1.5 µm by increasing calcination temperature from 350 to 1000°C. Investigation of the coating of uncalcined and calcined powder on AISI 430 ferritic stainless steel shows that a proper dense coating is developed on the stainless steel surface by using uncalcined precursor powders. And also, this coating performs well by prohibiting of outward diffusion of Fe from the substrate. In this way, a low thickness chromia layer (Cr2O3) is formed between the coating and the substrate. EDX analysis shows that a mixed spinel zone is formed in the interface of the coating and the substrate due to diffusion of some elements such as Mn, Cr, and Fe from substrate to the coating, as well as Mn and Co from coating to the substrate. Manuscript profile -
Open Access Article
788 - Investigation of Electrochemical and Mechanical Properties of Solid Oxide Fuel Cell Fabrication by 3d Printer
keyvan mirzaei feshalami zahra sadeghiyan Ramin EbrahimiNowadays, various methods have been introduced for the fabrication of solid oxide fuel cells (SOFC). In this research, 3D printing technology has been used to produce oxide fuel cells. First, a 3D printer was constructed that has the ability to print the MoreNowadays, various methods have been introduced for the fabrication of solid oxide fuel cells (SOFC). In this research, 3D printing technology has been used to produce oxide fuel cells. First, a 3D printer was constructed that has the ability to print the slurry of anode, cathode and electrolyte layers with the desired thickness and speed. Then a suitable slurry consisting of NiO-YSZ materials was produced for the anode layer, YSZ for the electrolyte layer and LSM for the cathode, with suitable solvents and additives. After cell formation, drying and then sintering of the layers were performed. The composition and microstructure characterization of layers has been performed by XRD, SEM, Mapping, EDS. The I-V-P curve showed the maximum power is around 0.84 W / cm2 at 800 OC with constant oxygen. The impedance curve values under open-circuit voltage were 0.23 Ωcm-2 and 1.25 Ωcm-2 at high and low frequencies, respectively. The tensile experiments indicated values 111 GPa for Young modulus and 137 MPa and 120 MPa values for the fracture toughness and the yield strength, respectively. Manuscript profile -
Open Access Article
789 - Effect of Hydroxyapatite Nanoparticles on Differentiotion of Mesenchymal Stem Cells into Bone cells in Polycaprolacton/Keratin/Hydroxyapatite Scaffolds
Mahboobeh Mahmoodi Mina Kalantari Marjan MirhajThe human body process can spontaneously repair small bone defects, while large bone defects cannot be repaired without medical interventions. Efforts to eliminate these shortcomings have led to the foundation of bone tissue engineering. In this research, polycaprolacto MoreThe human body process can spontaneously repair small bone defects, while large bone defects cannot be repaired without medical interventions. Efforts to eliminate these shortcomings have led to the foundation of bone tissue engineering. In this research, polycaprolactone/keratin scaffold and Polycaprolactone/keratin/hydroxyapatite scaffold were fabricated using electrospinning method and were evaluated. Then, in order to evaluate the cellular differentiation, adipose tissue-derived mesenchymal stem cells were cultured on scaffolds and the process of differentiation of mesenchymal stem cells into bone cells for 7 and 14 days was investigated by alkaline phosphatase and alizarin red test. Increase of the activity of the enzyme alkaline phosphatase, the presence of the minerals and the red-orange-color extended on the scaffolds containing hydroxyapatite nanoparticles that confirmed the presence of Ca + 2 , demonstrated the differentiation of mesenchymal cells into bone cells. Therefore, the results of this study suggest that the polycaprolactone/keratin/hydroxyapatite scaffold is a suitable substrate for proliferation and differentiation of stem cells for bone tissue engineering. Manuscript profile -
Open Access Article
790 - Synthesis and characterization of hollow mesoporous Silica nanocomposites via polystyrene template
Abolhassan Najafi Mahdi Khoeini Mostafa AmaniIn this study, the synthesis of hollow mesoporous silicate particles was studied using TEOS precursor in the presence of a polystyrene template and CTAB surfactant micelles. The process was carried out in based on alcoholic system with pH control and adding CTAB surface MoreIn this study, the synthesis of hollow mesoporous silicate particles was studied using TEOS precursor in the presence of a polystyrene template and CTAB surfactant micelles. The process was carried out in based on alcoholic system with pH control and adding CTAB surface activator at a suitable concentration. The results of the FTIR analysis showed that the pre-forming particles of TEOS formed surface boundaries during the synthesis process with CTAB surfactant agents. Also the presence of Si-O-Si bonds (range from 600 to 1320 cm-1) indicates the formation of silicate chains on polystyrene molds. Thermal analysis studies showed that using appropriate heat treatment and precise control, all organic compounds can be removed from the system and synthesized hollow mesoporous silica particle with the least structural defects at 380°C. The BET analysis showed that the specific surface of these synthesized mesoporous silicate particles is 1180 m2.g-1 X-ray diffraction results showed that the product obtained was amorphous silica and impurity phases are not formed in this system. The DLS analysis showed that the synthesized particles had dimensions ranging in size from 1 to 10 nm and the distribution of particle size has occurred in a narrow range. SEM images confirm the sphericality of nanoparticles with a mean size of 25-30 nm. Finally, the transmitted electron microscope images showed that the synthesized silicate particles were hollow, so that the diameter of the hollow cavity and its entire total diameter are about 30 and 80 nm, respectively. Manuscript profile -
Open Access Article
791 - Investigating the oxidation and electrical behavior of AISI 304 steel coated with cobalt for the application of solid oxide fuel cell
Mohammad Reza Ashorzadeh Morteza Zandrahimi Hadi EbrahimifarOxidation resistance and electrical conductivity of stainless steels used as interconnects in solid oxide fuel cells can be improved by using a conductive and protective coating layer. In this study, AISI 304 austenitic stainless steel was coated in a cobalt powder base MoreOxidation resistance and electrical conductivity of stainless steels used as interconnects in solid oxide fuel cells can be improved by using a conductive and protective coating layer. In this study, AISI 304 austenitic stainless steel was coated in a cobalt powder base pack mixture. Isothermal oxidation test was used to investigate the oxidation resistance of coated and non-coated steel. Area specific resistance (ASR) was also measured as a function of oxidation time at 800 °C. Microstructure of coated and oxidized samples was studied by scanning electron microscopy (SEM) and X-ray diffraction (XRD) device. The results showed that cobalt coated samples showed better oxidation resistance than non-coated samples. The results showed that increasing the temperature would increase the area specific resistance. The cobalt coating layer also converted to CoFe2O4, Co3O4 and CoCr2O4 spinels during the isothermal oxidation process. Cobalt spinels exhibited less ASR (27.4 mΩ cm2) compared to the uncoated sample (60.5 mΩ cm2). Manuscript profile -
Open Access Article
792 - Continuous electrowinning of nickel from dilute sulfate solutions
Alireza Zakeri Amirreza Sheikh KaramiSignificant amounts of nickel products used in different chemical processes and general applications leave them a valuable source of nickel at the end-of-life. Production of nickel from secondary sources is generally performed through hydro-electrometallurgical methods. MoreSignificant amounts of nickel products used in different chemical processes and general applications leave them a valuable source of nickel at the end-of-life. Production of nickel from secondary sources is generally performed through hydro-electrometallurgical methods. The resulting solutions from treatment of secondary nickeliferous resources are generally of low Ni concentration and electrowinning of them is challenging, particularly since Ni concentration in commercial operations is usually more than 80 g/L. In this paper, the continuous electrowinning of nickel from dilute sulfate solutions has been investigated. The effects of four variables of temperature, specific flow rate of electrolyte, current density, and nickel concentration on current efficiency and specific energy consumption were studied by a two-level full factorial design. From the statistical analysis of the results, it was found that current efficiency increases by rising all variables, while specific energy consumption decreases with specific flow rate of electrolyte, current density, and nickel concentration. By using the obtained statistical models, the optimum conditions to achieve a nickel deposit with high current efficiency as well as lowest energy consumption are determined to be 55 °C of temperature, 3 A/dm2 of current density, 3 h−1 of electrolyte specific flow rate, and 30 g/L of nickel concentration. Manuscript profile -
Open Access Article
793 - Comparative Study of the Effects of Strontium and Magnesium Ions on Physical and Chemical Properties of Calcium Phosphate-Gelatin Biomimetic Scaffolds in Bone Tissue Engineering
Amirhossein Moghanian Majid Raz Fathollah MoztarzadehIn this study, biomimetic scaffolds were designed to study the formation of calcium phosphate deposits by using a double diffusion method into gelatin hydrogel in temperature and pH similar to body conditions. Moreover, the effect of magnesium (Mg) and strontium (Sr) io MoreIn this study, biomimetic scaffolds were designed to study the formation of calcium phosphate deposits by using a double diffusion method into gelatin hydrogel in temperature and pH similar to body conditions. Moreover, the effect of magnesium (Mg) and strontium (Sr) ions on properties was investigated. Five different types of specimens with different Sr and Mg ions percentage were synthesized and then porous scaffolds were prepared by freeze-drying method. The scaffolds microstructures were examined by scanning electron microscopy (SEM), which showed a smooth and needle-shaped surface of specimens. Fourier transform infrared spectroscopy (FTIR) results indicated the presence of phosphate and hydroxyl bonds in the structure of the scaffolds, due to the formation of calcium phosphate phases such as HA. The presence of metal ions in the structure caused the displacement of the peaks in X-ray diffraction (XRD) analysis and lattice parameters. Additionally, osteoblast cell culture results also demonstrated M10 and S10 specimens had proper biocompatibility. Additionally, alkaline phosphate (ALP) activity revealed the optimal amount of 10 mol. % Mg and Sr (M10 and S10), which led to the significantly (**p< 0.01, ***p <0.001) growth, proliferation, and differentiation of 292G osteoblasts cells in scaffolds. Moreover, the presence of calcium phosphate improved the biological properties of the specimens. Finally, the results of various analyses confirmed the high capability of the synthesized scaffold as a promising substitute for bone tissue. Manuscript profile -
Open Access Article
794 - Investigation of the Effect of Strontium Ion Content on Thermal, Bioactivity, Antibacterial Properties and Behavior of MC3T3-E1 Osteoblast Cells in Silicate-Based Bioactive Glass
Noushin Nankali Amirhossein Moghanian Morteza Saghafi YazdiBioactive glass (BG), is able to bind to body tissues, in this regard, it can be considered suitable material for applications such as bone tissue engineering. In this study, we first synthesized and studied the structural changes, biocompatibility, in vitro bioactivity MoreBioactive glass (BG), is able to bind to body tissues, in this regard, it can be considered suitable material for applications such as bone tissue engineering. In this study, we first synthesized and studied the structural changes, biocompatibility, in vitro bioactivity, biological behavior and antibacterial properties of silicate-based BG containing with strontium. To evaluate the bioactivity, the BG powder was placed in a simulated body fluid (SBF) solution for 1, 3, 7 and 14 days and then before and after the mentioned time periods, the changes and the process of forming a hydroxyapatite (HA) layer on their surface was studied by using X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), release rates of various ions elements, pH changes and scanning electron microscopy (SEM). The results of X-ray diffraction tests and infrared spectroscopy studies confirmed the formation of crystalline HA layer on the BG surface. Moreover, the results of live/dead assay, nucleus microstructure and actin microfilaments of MC3T3-E1 osteoblast cells showed that 5% of strontium in silicate-based bioactive glass led to the growth, proliferation and activity of MC3T3-E1 osteoblast cells. The results of cytotoxicity test and evaluation of alkaline phosphate activity showed that substitution of strontium instead of calcium in silicate-based bioactive glass composition not only did not cause cytotoxicity but also caused significant proliferation and activity of MC3T3-E1 osteoblast cells. Meanwhile, improvements in the antibacterial properties of strontium-containing bioactive glass against MRSA bacteria were observed in comparison with strontium-free bioactive glass. Manuscript profile -
Open Access Article
795 - Achillea Santolina Hydroalcoholic Extract Induces Cell Death in Breast Cancer MCF-7 Cells Cultured in Fibrin Gel
Elham Hoveizi Peyman Abdolali nejad It is a continuing effort to develop new anticancer compounds. Some studies have reported that some compounds of Achillea Santolina have inhibitory effects on several cancer cell lines. The present study aims to evaluate the cytotoxic effect of the hydroalcoholic More It is a continuing effort to develop new anticancer compounds. Some studies have reported that some compounds of Achillea Santolina have inhibitory effects on several cancer cell lines. The present study aims to evaluate the cytotoxic effect of the hydroalcoholic extract of Achillea Santolina on MCF-7 human breast cancer cells in fibrin hydrogel. In this experimental study, to prepare the fibrin hydrogel scaffold, an M199 medium containing 10% FBS, 1% penicillin/streptomycin, fibrinogen powder with a concentration of 3 mg/ml, and thrombin with a concentration of 120 u/ml was used. Cultured MCF-7 cells in fibrin gel were treated with hydroalcoholic extract of Achillea Santolina in 25, 50, 100, 250, 500, and 1000 mg/ml concentrations for 24h. Morphology and cellular viability and proliferation were evaluated by DAPI staining and MTT assay at certain days after treatment. Also, the structure of the scaffold and the condition of the cells in the gel were investigated by photographing with a scanning electron microscope.The results of this study showed the cytotoxic effects of Achillea Santolina extract in a dose- and time-dependent manner. The concentration of 500 mg/ml of the extract of A. Santolina was determined as an IC50 concentration. Also, cell viability in the control group and treated group with extract at IC50 concentrations showed significant (P<0.05) differences on days 1, 3, and 5. The hydroalcoholic extract of Achillea Santolina can inhibit MCF-7 cell proliferation and induce cell death in a dose and time-dependent manner. Manuscript profile -
Open Access Article
796 - Cytotoxicity Effects of Citrus Skin Extract On Cancer Cell Line MCF-7
عباسعلی دهپور جویباری زهرا حسن پورNowadays, cancer is knownas the main cause of death throughout the word. In recent decades, medical and molecular advances have not only been able to find the reasons and mechanisms of cancer, but they were more successful in early diagnosis and treatment of it. Citrus MoreNowadays, cancer is knownas the main cause of death throughout the word. In recent decades, medical and molecular advances have not only been able to find the reasons and mechanisms of cancer, but they were more successful in early diagnosis and treatment of it. Citrus skin is the accumulation center of many antioxidant and enzymes. Flavonoids and limonene are among the important compounds in the citrus skin and their vital rolesin prevention and treatment of cancer is under study these days. In this research, after cultivation and reproduction of MCF-7cancer cells line and in order to determine, the effectof cellular cytotoxicity of citrus skin extract, these cells were put in exposure to different doses of etanolic extract and after 72 hours, MTT test was done. Results indicate that the ethanolic extract of Orange skin at concentrations 7.5,10 (p ≤ 0.05)and the ethanolic extract of Limon skin at concentrations 2.5,5 (p ≤ 0.01)decrease cell growth significantly in comparition with the control group. the effectof cellular cytotoxicity grows with an increase in the concentrationof extract and the highest percentage of growth inhibition in extract of Orange skin and Limon skin is related to the concentrations of 7.5 and 5 respectively. Thus citrus skin extract is suggested as an effective material in curing cancer in medical advances. Manuscript profile -
Open Access Article
797 - Effects of Cytotoxicity of Nanoparticles of Ag/Si_O_P /Gelatin on Uterus Cancer Cell Lines (Hela)
سیده مبینا موسوی سروینه باغی عباسعلی دهپور جویباری صدف فرخندهNowadays, cancer is the second cause of mortality in the world and among its variants; the most common cancer in women is the ovary cancer. One of the methods for cancer treatment is chemical therapy. Some nanoparticles can be considered as a sensitizer because they enh MoreNowadays, cancer is the second cause of mortality in the world and among its variants; the most common cancer in women is the ovary cancer. One of the methods for cancer treatment is chemical therapy. Some nanoparticles can be considered as a sensitizer because they enhance the cytotoxicity due to oxidative stress and increase the free radicals, especially reactive oxygen species (ROS), within cells resulting in cell death. In this study, elevated synergistic effect of Ag/Si_O_P /gelatin nanoparticles as radiosensitizer was evaluated in presence of cobalt-60 gamma rays on human ovary cancer cell line. In this experimental and laboratories study ,after duplication and farming the Hela cell class, gelatin silver nanoparticles with10, 20, 40, 60, 80, 160 densities are effected by Hela cancer cells, and after 72 hours of using MTT, the cytotoxicity is evaluated and the data are analyzed by Elisa Reader and Anova. The Results shown that silver nanoparticles of (p≤5%) 20, 40, 80 density after 72hours, the cell growth is significantly decreased according to controlled group. Silver nanoparticles of different sizes and density of this study is shown that gelatinous nanoparticle have effective cell relation or cancer cell (Hela) and highly induced apoptosis in cells and caused the death of cancer cell and have the lower poisonous to natural body cells. Manuscript profile -
Open Access Article
798 - Cytotoxic Effects of Myrtus communis Extract on Hela and MCF7 Cancer Cells
سحر حبیب زاده خامنه فرخنده نعمتی عبدالحسین شیرویThis study aimed to investigate the effects of Myrtus communis extract in 10, 7.5, 5, 2.5, 1.25, 0.625, 0.312, 0.156 mg/ml concentration on Hela and MCF7 cell lines after 72 h using the MTT assay. Hela and MCF7 cells were cultured in RPMI1640 medium containing fetal bov MoreThis study aimed to investigate the effects of Myrtus communis extract in 10, 7.5, 5, 2.5, 1.25, 0.625, 0.312, 0.156 mg/ml concentration on Hela and MCF7 cell lines after 72 h using the MTT assay. Hela and MCF7 cells were cultured in RPMI1640 medium containing fetal bovine serum, penicillin and streptomycin and incubated at 37 anddeg; C atmosphere containing 5% CO2 and 95% humidity in sterile flasks. Results show that ethanolic extract of M. communis in 1.25 mg/ml (p andle; 0.05), and 0.312, 0.156 (p andle; 0.02) concentration, was significantly reduced Hela cell growth compared to control, after 72 h. The highest percentage of growth inhibition at 0.625 mg/ml concentration was % 82.33. For MCF7 cells, ethanolic extract of M. communis in 2.5, 1.25, 0/312 mg/ml (pandle; 0/02) and 0.625 (pandle; 0/001) concentration was significantly reduced MCF7 cell growth compared to control, after 72 h. The highest percentage of growth inhibition at 1.25 mg/ml concentration was 70.64 %. The results suggest that ethanolic extract of M. communis has inhibitory effects on cell growth both on Hela and MCF7 cell line. Manuscript profile -
Open Access Article
799 - Effect of Aloe vera Extract on Spermatogenesis and Reproductive Hormones in Mice
مهرداد مدرسی حمیدرضا خدائی علیرضا خدادادیAloe with the scientific name Aloe vera is a perennial plant that has useful effects in herbal therapy and herbal medicine. In this research the effects of hydroalcoholic extract of Aloe vera gel on the testis and spermatogenesis in mice Balb/C mice were examined. Sampl MoreAloe with the scientific name Aloe vera is a perennial plant that has useful effects in herbal therapy and herbal medicine. In this research the effects of hydroalcoholic extract of Aloe vera gel on the testis and spermatogenesis in mice Balb/C mice were examined. Samples randomly divided into five groups (three treatment groups, placebo and control) and all samples were kept in the same conditions. Aloe vera gel extract in different doses (50, 100 and 200 mg/kg/2day) produced by intraperitoneal (IP) for 20 days was administered to the treatment group. Placebo group was used as the injection of saline. The main parameters that were examined changes in levels of testosterone, LH and FSH levels and changes in stem cell number, number primary spermatocytes, and testis weight compared with the control group. All of hormonal experiments using Radioimmunoassay (RIA) were performed.The results showed that Aloe vera extract caused a significant increase in the number of stem cells and primary spermatocytes in the experimental group compared with the control group. Mean of testicular weights and testosterone levels in group 3 (200 mg/kg) increased significantly, while LH and FSH levels did not show significant changes. The findings indicate Aloe vera extract in a dose-dependent effect on testosterone levels and histological characteristics of male mice. Manuscript profile -
Open Access Article
800 - Cytotoxicity Effects of the Ferula gummosa Extract on the Cancer Cell Line MCF7
بهمن اسلامی جدیدی عباسعلی دهپوری فرخنده نعمتی بشری رضاییBreast cancer is the second most pervasive cancer among women. Breast cancer is a worldwide epidemiological problem which the current remedies cannot heal it effectively and has unwanted side effects. Therefore, attempt to produce more effective medicine with less toxic MoreBreast cancer is the second most pervasive cancer among women. Breast cancer is a worldwide epidemiological problem which the current remedies cannot heal it effectively and has unwanted side effects. Therefore, attempt to produce more effective medicine with less toxicity is essential. Ferula gummosa is anti-cancer, anti-spasm, anti-paroxysm, antiseptic and laxative and it is tonic for stomach, reconstructs surface scars, and causes more milk producing in breasts. Since, its anti-tumorous effects have not been studied on the breast cells; the cellular toxicity effect of its ethanolic extract was investigated in this study. To investigate the preventing effects of F. gummosa ethanolic extract on cellular growth, we have used the MCF7 (Human Caucasian breast adenocarcinoma) cell line which has been cultivated in RPMI environment containing cowand#39;s embryo serum and antibiotic. Then we treated these cells in different concentrations of F. gummosa ethanolic extract (0.165, 0.312, 0.625, 1.25, 2.5, 5, 7.5, and 10 mg/ml) for 72 hours. The amount of cell viability was determined by MTT method. Ethanol extract of F. gummosa has a significant cellular toxicity effect on the MCF7 cell line in 0.625, 1.25, 2.5, 5, 7.5, and 10 mg/ml densities after 72 hours compare with control group, and the calculated IC50 for F. gummosa extract was 1.765 mg/ml. The results suggest that ethanol extract of F. gummosa has preventing effect on the cellular growth of MCF7 cellular class. Manuscript profile -
Open Access Article
801 - The Effect of Embryonic Cartilaginous Tissue Extract on Differentiation of Mesenchymal Stem Cells to Osteoblasts
مرضیه رمضانی رمضان خان بابایی ویدا حجتیAllstem cells are originated from both embryonic stem cells and adult stem cells. The most important adult stemcellsaremesenchymal stem cells. Mesenchymal stem cellsare pluripotentandnon-hematopoietic cellswithahighdifferentiation potential.There arein thebone marrowand MoreAllstem cells are originated from both embryonic stem cells and adult stem cells. The most important adult stemcellsaremesenchymal stem cells. Mesenchymal stem cellsare pluripotentandnon-hematopoietic cellswithahighdifferentiation potential.There arein thebone marrowand otherskeletal tissues.Mesenchymalstem cellsderivedfrombone marroware capabledifferentiationto osteoblast, osteocyte,adipocyte, chondrocyte, tendonsand muscle cells underin vivoandin vitro.In vitro osteoblastic differentiation needs to a variety of factors, which creates condition similar to bone tissue microenvironment. In this study, the effects of embryonic cartilaginous tissue extract was studied to differentiation of bone marrow mesenchymal stem cell into osteoblast. Mesenchymal stem cells were isolated from mice bone marrow and cultured in flasks containing DMEM-F12, 100 andmu;g/ml streptomycin, 100 U/ml penicillin and 10% FBS.Mesenchymal stem cellswerepurifiedbyseveral passages, then cellswere affectedby 15day mouse cartilaginous tissue extraction. After21 days ofculture, Alizarin Red staining was usedfor the detection ofosteoblasticcells.Aftereffect of extraction, spindle-shaped mesenchymal stem cellschange theirshapeAndmany appendages was observedincells. Alizarin Red staining has shown osteoblasticdifferentiation ofmesenchymal stem cells.Also osteoblastic differentiation of mesenchymal stem cells has confirmed morphogenic and osteogenic factors at cartilaginous tissue extracts of 15-day mouse embryo. Theresults express of osteoblastic differentiation of mesenchymal stem cells.Therefore, it is used in vitro models of osteoblast differentiation and genetic diseases of bone. Manuscript profile -
Open Access Article
802 - Cytotoxicity Effects of Bishops Flower (Ammi majus) Extract on the Cancer Cell Lines Hela and MCF-7
فرخنده نعمتی بهمن اسلامی جدیدی مهدیه طالبی دارابیTodaymany of the treatment methods are used to treat cancer. Unfortunately, in most cases very poor response is often associated with undesirable side effects. AlphaLack ofresponse to treatment and the rapid growth of the disease, has been made researchers to achieve mo MoreTodaymany of the treatment methods are used to treat cancer. Unfortunately, in most cases very poor response is often associated with undesirable side effects. AlphaLack ofresponse to treatment and the rapid growth of the disease, has been made researchers to achieve more effective drugs with fewer side effects. In this study the effect of ethanolic extraction of theBishopand#39;s Flower, Ammi majus on the cancer cell lines Hela and MCF-7 were examined. Cells were cultured in cell culture flasks then transferred to 96 well plates with 10,000 cells. Cells were exposed to different concentrations of Ammi majus. The cytotoxicity of Ammi majus was assessed using the MTT assay after 72 hours. The results of this study showed that ethanolic extract of Ammi majus on Hela cells was significantly reduced the cells grow compared with controls after 72 h. The calculated IC50, was 1/922 mg / ml. The cytotoxicity effect this extract on MCF7 showed that Ammi majus was significantly reduced the MCF7 cells grow compared with controls after 72 h. The calculated IC50, was 10 mg / ml. The effect of this extracts on normal cells (lymphocytes and monocytes in blood) is granted, the results show that the concentration of 10 mg / ml extracts had no effect on normal cells. The results suggest that ethanolic extract of the plant Ammi majus inhibits growth of cancer cells MCF7 and Hela. Manuscript profile -
Open Access Article
803 - The Effects of Vitex Agnus Castus and Foeniculum volgare Alcholic Extract on HPG Axis and Spermatogenesis of NMRI Mice
راحله فاضلی عبدالحسین شیرویVitex agnus castusand Foeniculum volgare are phytoestrogeic herbs native to the Middle East and southern Europe. They have clinical usage in so many countries. In this research, the effects of Vitex agnus castus fruit extract and Foeniculum volgare seed extract were inv MoreVitex agnus castusand Foeniculum volgare are phytoestrogeic herbs native to the Middle East and southern Europe. They have clinical usage in so many countries. In this research, the effects of Vitex agnus castus fruit extract and Foeniculum volgare seed extract were investigated on spermatogenesis and Testosterone, LH and FSH Hormon of male NMRI mice.This is an experimental study in which adult male mice were chosen and divided into 3 groups: control, vehicle, and experimental. Animals were daily injected (i.p.) with 100 , 200 mg/kg of Foeniculum volgare seed extract and 200 , 300 mg/kg of Vitex agnus castus and synthetic dos of Vitex agnus castus (300) + Foeniculum volgare (200) for 15 consecutive days. Then the animals were weighed and eventually killed. 2 weeks after the last injection.Testosterone and LH, FSH serum hormone of animal was assayed .The caudal part of the epididymis was used for sperm counting. After macroscopic investigation (weight, diameter and volume of Testes and weight of epididymis) tissues were fixed in Buinand#39;s fixative. Tissues were cut at 5 andmu;m, stained with Hematoxylin and Eosin (Handamp; E).Collected data was analyzed by the SPSS software by using one-way ANOVA. No significant differences in volume, weight and diameter of testes and weight of epididymis was seen. Significant reduction in LH, FSH and Testosterone hormon in all of experimental group was seen. Light microscopic studies showed a significant reductionin in number of germinal cells and several holes that were found scattered in the tubules and Testis also showed a general disarrangement in various germinal elements of seminiferous tubules in doses of 200 , 300 vitex agnus castus and synthetic dose. Result of sperms count indicated a significant decreasing of spermatozoa in all of experimental groups. Vitex agnus castus and Foeniculum volgare contains essential oils, iridoid, glycosides, flavonoids diterpenes, and essential fatty acids. The results suggest that its contraceptive effects is related to its flavonoids and essential fatty acids but further studies is needed to focus on the pharmacokinetics of this plants. Manuscript profile -
Open Access Article
804 - The Effect of Celery (Apium graveolens) Extract on the Pituitary – Gonad Axis in Adult Male Mice
مهرداد مدرسی غلامرضا قلمکاریCelery (Apium graveolens) has many therapeutic effects. This plant has many phytoestrogens that can affect on the reproductive endocrine system and can reduce fertility .In this study, Hydro alcoholic extracts of celery leaves on the pituitary -gonad axis in male mice o MoreCelery (Apium graveolens) has many therapeutic effects. This plant has many phytoestrogens that can affect on the reproductive endocrine system and can reduce fertility .In this study, Hydro alcoholic extracts of celery leaves on the pituitary -gonad axis in male mice of Balb/C was investigated. The samples were randomly divided into 5 groups (three treatment groups, placebo and control). Celery leaves hydro alcoholic extract in different doses (50, 100,150 mg/kg/2day) was injected (IP) for 20 days. The Placebo group was used for injection of normal saline. The samples were randomly divided into 5 groups (three treatment groups, placebo and control). Celery leaves hydro alcoholic extract in different doses (50, 100,150 mg/kg/2day) was injected (IP) for 20 days. The Placebo group was used for injection of normal saline. After 10 injections, samples bloods were analyzed for FSH, LH and testosterone using RIA method and compared with control groups. Concentrations of FSH in 100 and 150 mg/kg decreased significantly while LH and testosterone concentrations in all experimental groups decreased (Pandlt;0.05) .This study showed dose-dependent negative effect of celery extracts in the pituitary - gonad axis in male mice Manuscript profile -
Open Access Article
805 - The Effect of Camphor on Leydig Cells and Concentration of Testosterone and LH Hormones in Adult Male Mice, Balb/C Strain
مریم عابدینی وحید حمایت خواه جهرمی محسن فروزانفر حسین کارگر جهرمیCamphor is a plant from Lauraceae family. Investigations have shown that this plant has probably impression on controlling of sexual power. In this investigation, camphorandrsquo;s effect on spermatogenesis procedure has been worked out.Investigated parameters are the n MoreCamphor is a plant from Lauraceae family. Investigations have shown that this plant has probably impression on controlling of sexual power. In this investigation, camphorandrsquo;s effect on spermatogenesis procedure has been worked out.Investigated parameters are the numbers of Leydig cells, sperm and testosterone concentration and LH. We use 36adult male mice with average weight of 34 andplusmn; 1 gr and age of 10 weeks.The animals divided to 9 groups with 4 animals in each group. The control group received no injection. The sham group received olive oil as camphorandrsquo;s dissolver. The treatment animals received camphor solution in concentration of 5,20 and 50 mg/kg(b.w) each amount 0/02 cc intraperitioneally for 2 weeks. Treatment group were sacrificed 1 day after the last injection and the posttreatment group 1 week after that. After injection, the animals were weighed.Then bloodsampling and sacrificed. The results show significant increase at P andlt; 0/05 in the number of Leydig cells and sperm and concentration of testosterone and LH in treatment animals than control animals. Thus due to increase of the mentioned hormones and the number of Leydig cells and sperm it is concluded that camphor may cause increasing of spermatogenesis. Manuscript profile -
Open Access Article
806 - Evaluation of colonization ability of lactobacilli isolated from traditional cheese and adherence to epithelial cells of human GI tract, Caco-2 cell line
میترا حیدری نصرآبادی مریم تاج آبادی ابراهیمی هدی بهرامیThe aim of this study was to assesandrsquo;colonization ability of 7 lactobacilli strain isolated from traditional cheese in GI[1] trace. So resistance to acidic pH, bile salt and ability to adhere Caco-2 cell line was assessed in vitro. 2 hour acidic treatments lead to MoreThe aim of this study was to assesandrsquo;colonization ability of 7 lactobacilli strain isolated from traditional cheese in GI[1] trace. So resistance to acidic pH, bile salt and ability to adhere Caco-2 cell line was assessed in vitro. 2 hour acidic treatments lead to 0-4 log reduction of tested strains. Isolate B1D2was fully resistance and no reduction in population observed after acid treatment. Bile salt cause growth delay between 25-180 min for all strains and BH1with D= 25 andplusmn; 4.80 min was the most resistance strain. Ability to adhere Caco-2 cell line was strain depended and GI2 and SL2 were less and most adherent strain respectively. In conclusion evaluation of these 3 factor in vitro indicated that SM3, BD2, SM1, SL2 isolated from Semnan and Babol cheese have colonization ability Manuscript profile -
Open Access Article
807 - The effect of electromagnetic field with 50HZ frequency on the count blood cell of NMRI mice
نفیسه پذیره پریچهر یغمایی کاظم پریور وحیده سادات عباس نیا بهمن دلالت داود دورانیانIncreasing applications of electric and electromagnetic fields have caused some anxieties in human health. This research work has been done on the effects of 0.04 T and 0.06 T intensities with 50HZ frequency in blood cell of adult NMRI mice. In this work solenoid coils MoreIncreasing applications of electric and electromagnetic fields have caused some anxieties in human health. This research work has been done on the effects of 0.04 T and 0.06 T intensities with 50HZ frequency in blood cell of adult NMRI mice. In this work solenoid coils to produce electromagnetic fields were used two experimented groups (n=12) were exposed to electromagnetic wave four hours a day for 28 days. The results of experimental groups were compared with sham groups (n=6) and controls (n=6). Electromagnetic investigation of blood cell showed significant decrease of red blood cell(RBC) , white blood cell(WBC) , platelet (Pt) , hemoglobin (Hb) and MCHC (pandlt;0.05) in 0.06 and 0.04 mT electromagnetic field compared with sham and control groups. The amount of MCV and MCH increased at the same field significantly. Mean value of hematocrit in different groups did not show significant change.Results of this research work showed electromagnetic field could effect on the blood cell, As a result of damage on liver cells because of being exposed electromagnetic were this change will happen. Manuscript profile -
Open Access Article
808 - Assessing the levels of CREB after siRNA mediated knockdown in K562 cells
زهرا دیلمی خیابانی مهدی بنان علی محمد اصغریان جلال قره سوران غلامرضا جوادی کیمیا کهریزی حسین نجم آبادیBackground: CREB is an important downstream protein for many signaling pathways. By having efficient siRNAs against CREB, it may be possible to assess the role of molecules involved in signaling pathways in different cell types. In this research the efficiency of CREB k MoreBackground: CREB is an important downstream protein for many signaling pathways. By having efficient siRNAs against CREB, it may be possible to assess the role of molecules involved in signaling pathways in different cell types. In this research the efficiency of CREB knockdown by 2 different siRNAs in HeLa cells has been studied. Materials and methods: HeLa cells were transfected by siRNAs using Lipofectamine 2000. RNA extraction and cDNA synthesis have been done. The efficiency of CREB knockdown has been assessed by quantitative relative real time PCR. According to our results only one of the siRNAs has a high level of inhibitory effect on CREB gene expression in HeLa cells. The expression of CREB by this siRNA was knocked-down by 64.4% in HeLa cells. Conclusion: By using efficient siRNA specifically for knocking down of CREB gene, we can apply this efficient siRNA in different cell types due to study of signaling pathway which CREB may be involved. Manuscript profile -
Open Access Article
809 - Culture and proliferation of dendritic cells from mouse bone marrow progenitors
سمانه عرب معصومه معتمدی جمشید حاجتیDendritic cells (DCs) are the most potent antigen-presenting cells that induce and control the immune responses. These cells have the capacity of stimulation different types immune response (type 1 or 2) in exposure to peripheral signals. The aim of this study was DCs c MoreDendritic cells (DCs) are the most potent antigen-presenting cells that induce and control the immune responses. These cells have the capacity of stimulation different types immune response (type 1 or 2) in exposure to peripheral signals. The aim of this study was DCs culture, proliferation and maturation from mouse bone marrow progenitors. Bone-marrow derived DCs (BMDCs) were cultured in the presence of GM-CSF and IL-4. After 5 days, LPS and cholera toxin were added to the culture for another 2 days. Expression of surface molecules and cytokine production in BMDC culture evaluated. The result shown that LPS stimulated DCs were matured. Exposure with CT induce IL-10 and with LPS induce IL-12 production by DCs. These fundings indicate that 7 days culture of mouce bone marrow progenitors can produce professional dendritic cells and with added different components in DCs culture induce appropriate type 1 or 2 of immune responses. Manuscript profile -
Open Access Article
810 - Effects of (Physalis alkekengi) fruit’s alcoholic extract on development of placentas in pregnant wistar rats
مهناز نسیمی میترا حیدری نصرآبادی عبدالحسین شیرویIn the present study, the teratogenic effects of Physalis alkekengi on the development of placentas at 4th and 6th days of pregnancy had been studied. Material and Methods: Thirty female rats as random divided to 6 groups including control, experimental 1 and experi MoreIn the present study, the teratogenic effects of Physalis alkekengi on the development of placentas at 4th and 6th days of pregnancy had been studied. Material and Methods: Thirty female rats as random divided to 6 groups including control, experimental 1 and experimental 2 groups that each one at the 4th and 6th day of pregnancy received doses 8g/kg body weight and 10g/kg body weight and experimental 3 group that at 6th day pregnancy received dose 12g/kg of Physalis alkekengi fruitandrsquo;s alcoholic extract. All placentas removed from uterus at the 15th day of pregnancy to study according to morphologic and histologic. The present data showed that Physalis alkekengi fruitandrsquo;s alcoholic extract injection intraperitoneal at the 4th and 6th days of pregnant rat caused significant reduction of placentas diameter and weight and volume in experimental groups in comparison with control group and reduction of diameter and weight and volume in experimental 2 group in comparison with control group. Also morphologic studies showed that had been blood corona at the percent out of placentas experimental groups in comparison with control group. In addition tissue Studies showed the significant increase of the hofbauer cells number at placentas experimental groups in comparison with control.Physalis alkekengifruitandrsquo;s alcoholic extract through suppression of cell division and differentiation and function reduction of some of enzymes and hormones, probably can have negative effects on placentas deficiency development and cell differentiation of some cells. According to reported physiological effects of physalins such as physalin F, alcoholic extract teratogenic effects might be related to physalin F. But it is essential to have more quantitative and qualitative researches in order to have conclusive result. Thus it is recommended to pregnant womenfolk than up to researches completion about this medicinal plant have not used this plant in pregnancy period. Manuscript profile -
Open Access Article
811 - Cytotoxicity Effects of Ammi visnaga Extract on Hela and MCF7 Cancer Cell Line vvررررررررررررررر
هدیه پاک فطرت فرخنده نعمتی عبدالحسین شیرویThe discovery of new materials such as anti-microbial and anti-viral and anti-cancer known among plants or those who have recently been discovered can help to treat diseases. In this study, the cytotoxic effect of plant extracts Ammi visnaga extract on Hela and MCF7 cel MoreThe discovery of new materials such as anti-microbial and anti-viral and anti-cancer known among plants or those who have recently been discovered can help to treat diseases. In this study, the cytotoxic effect of plant extracts Ammi visnaga extract on Hela and MCF7 cell lines were analyzed. Different concentrations of ethanolic extract of the Ammi visnaga on cultured blood cells and cancer cell line for 72 hours were examined. The cytotoxicity was evaluated by MTT test. Results are reported as IC50. This study showed that different concentrations of Ammi visnaga extract have cytotoxic effect on Hela and MCF7 cell lines. The percentage of growth inhibition of Hela and MCF7 cells increasing whit whit increasing concentration of test compounds. IC50 value for Hela was 0.57 mg /ml, and for MCF7 was 2mg/ml. The results suggest that ethanolic extract of Ammi visnaga has inhibitory effect on cell growth of MCF7 and Hela cell lines. vv Manuscript profile -
Open Access Article
812 - Cytotoxic Effect of Enteromorpha clatherata Extract on Hela and MCF7 Cancer Cell Lines
ریحانه مهری دیوکلایی فرخنده نعمتی پروین خدارحمی عباسعلی دهپورCancer is the second cause of death in the world. Current therapies for treating cancer are often restricted by short-term efficacy, even lead to the drug resistance. There has been increased interest in the use of natural compounds with chemotherapeutic effects for tre MoreCancer is the second cause of death in the world. Current therapies for treating cancer are often restricted by short-term efficacy, even lead to the drug resistance. There has been increased interest in the use of natural compounds with chemotherapeutic effects for treatment of cancer. In this study, the effects of different concentrations of ethanolic extract of Enteromorpha clatherata, on human breast cancer cell (MCF-7) and cervix cancer cells (Hela) were investigated. Cell were produced in Pasteur Institute and were cultured under controlled conditions with RPMI containing 10% FBS and penicillin streptomycin in cell culture flasks, the cells were transferred to 96 well plates with 10.000 cells. Cells were exposed to different concentrations of extracts (0.156, 0.312, 0.625, 1.25, 2.5, 5, 7.5 and 10 mg/ml) that had been dissolved in RPMI with FBS. Cells cultured with all conditions without the presence of the drug as a control for 72 hours and cell toxicity was assessed with the MTT assay after 72 hours. The result of this study showed that ethanolic extract of Enteromorpha clatherata on both Hela cell and MCF-7 in 0.625 mg/ml concentration consistency reduces the growth of cells significantly in comparison to control group. This extract possesses cytotoxic effects in 0.156, 0.312, 1.25 concentrations and inhibit the growth of cells to 48 %, 66 % and 66 % in Hela and to 56 %, 65% and 70 % in MCF-7 MCF-7 in 0.625 mg/ml. The IC50 is 0.17 mg/ml in Hela and 0.19 mg/ml MCF-7 respectively. The results show that ethanolic extract of Enteromorpha clatherata caused the growth inhibition of cancer cells in Hela and MCF-7. Manuscript profile -
Open Access Article
813 - Histogenesis Study of Fetal Cerebellum in Gezel sheep
سیدسجاد حجازی علی خوش سوداThe purpose of this study is to determine the differentiation time of cerebellum tissue during fetal life. This study is a descriptive observation of 100 fetuses of pregnant sheep uterus that were chosen randomly. After fixation, morphological measurement and preparing MoreThe purpose of this study is to determine the differentiation time of cerebellum tissue during fetal life. This study is a descriptive observation of 100 fetuses of pregnant sheep uterus that were chosen randomly. After fixation, morphological measurement and preparing histological sections, the samples were stained by HandE and were examined under a light microscope. According to microscopic observations of 40th day of gestation, cerebellum tissue had not yet differentiated. Therefore, at this stage, the appearance of cerebellum was like an overlying mass of neuroepithelial cells in metencephalon area of neural tube. At the 50th day of gestation, the initial form of the cerebellum was separable due to the placement of migrating cells in layers and creating initial wrinkle under the pia mater. At the 70th day, great number of wrinkles could be seen on long strips in a way that primary wrinkle was underneath the secondary wrinkle. At the 80th day of gestation, Purkinje cells were observed between granular and molecular layers. At the 90th day of gestation, cerebellum tissue had primary, secondary, and tertiary wrinkles. At the 120th day, the whole tissue structure of cerebellum, in the last month of pregnancy, was seen as a mature form in a way that in the last three months there were no significant changes. This can be concluded that the differentiation of cerebellum tissue from the mass of migrating cells of neural tube starts after the sixth week and the whole cerebellum tissue structure appears in fetal life and a month before birth. Manuscript profile -
Open Access Article
814 - Evaluation of the Differentiation Potential of Human Theca Stem Cells to Oocyte-Like Cells in the Ovary of Women of Different Reproductive Ages
Seyedeh Nasim Mirbahari َAzam Dalman Fatemeh Hasani Mehdi TotonchiThe evidence about the existence and function of ovarian stem cells (OSCs) is increasing. In a previous study, we isolated human theca stem cells (hTSCs) from the ovary of a 19-year-old patient and differentiated them into oocyte-like cells (hOLCs) under induced conditi MoreThe evidence about the existence and function of ovarian stem cells (OSCs) is increasing. In a previous study, we isolated human theca stem cells (hTSCs) from the ovary of a 19-year-old patient and differentiated them into oocyte-like cells (hOLCs) under induced conditions. In this study, in order to prove the repeatability of this experiment as well as the presence of these cells in the ovaries of patients with higher reproductive age and their differentiation potential in-vitro, hTSCs were isolated from the ovaries of 20 and 38-year-old patients and their differentiation potential into hOLCs has been evaluated. In this experimental interventional study, based on the instructions of the previous study, hTSCs were isolated from small antral follicles with a size of 3 to 5 mm. These cells were cultured in six-well plates with A number of 5×104 cells per well in DMEM/F12 induction medium containing FBS, human follicular fluid, glutamine and pyruvate for 40 days. Then their development process was measured by assessing the morphology, size and viability. hTSCs were successfully isolated from ovarian tissue of 20 and 38-year-old patients and cultured in DMEM/F-12 medium containing growth factors (EGF, FGF, GDNF, etc.). After 12 days, hTSCs in both patients started to differentiate into hOLCs and their morphology changed from spindle-shaped to round. The size of hOLCs increased during the differentiation period in both patients (from 20-25 µm to 50 µm). The survival of hOLCs compared to hTSCs was similar in all three patients and did not differ significantly. hTSCs can be isolated from ovaries of women of different reproductive ages and there is no difference in their differentiation pattern to hOLCs in laboratory (in-vitro) conditions. Manuscript profile -
Open Access Article
815 - Morphological Change of Kidney after Injection of the Biological Gold Nanoparticles in Wistar Rats
Behrooz Yahyaei Parastoo Pourali Maryam HassaniGold nanoparticles have different uses in medicine. Since the produced chemical nanoparticle is reviewed but the character of the biological one is not checked sufficiently. Therefore, this study on the poisonous effects of the cells in the produced biological nanoparti MoreGold nanoparticles have different uses in medicine. Since the produced chemical nanoparticle is reviewed but the character of the biological one is not checked sufficiently. Therefore, this study on the poisonous effects of the cells in the produced biological nanoparticles is done on the rat’s kidney. After preparing bio-gold nanoparticles from Bucillus subtilis and sterilization bacteria, the nanoparticles were calculated in toxic and non-toxic doses and injected into rats at two doses in 48 hours. Then, after 24 hours, tissue sampling and histological examination were performed. The nonpoisonous nanoparticle injection caused the glomerulus to be smaller & contracted but the other assumes are normal. Nevertheless, the poison injection caused the glomerulus to be fewer in some parts. Dilatation and enlargement was seen in urine space and some glomeruli are smaller and more compressed. The kidneys tubules had no problems but there was a little hyperemia in interstitial space. The usage of biological nanoparticles via the non-biological one had little poisonous effects and the poisonous effects were dosage related. Manuscript profile -
Open Access Article
816 - The Chemical Inhibitory Effect of G9a Enzyme on Decrease of Proliferative Potential and Increase of the Adipogenic Propensity of Mesenchymal Stem Cells
Hedyeh Khanban Esmaeil Fattahi Mahmoud TalkhabiMesenchymal stem cells (MSCs) have unique properteis such as immunomodulatory function, secretion of cell survival factors, and the potential of bone , cartilage, and fat differentiation. All of the cellular processes including differentiation, proliferation, aging, and MoreMesenchymal stem cells (MSCs) have unique properteis such as immunomodulatory function, secretion of cell survival factors, and the potential of bone , cartilage, and fat differentiation. All of the cellular processes including differentiation, proliferation, aging, and cell death are directly or indirectly regulated by epigenetic mechanisms such as histone methylation. G9a histone methyltransferase is one of the most important enzymes controlling cell behaviors. MSCs were isolated from rat bone marrow (BM-MSCs) and cultured in vitro. Bone marrow-derived MSCs (BM-MSCs) were treated with different doses of A366 (a specific G9a inhibtior) at the passages 1-3 of the primary culture. Then the proliferative capacity of BM-MSCs was analyzed using flowcytometry, assessment of the cell population doubling time, and studying the cell-cycle profile. The rate of adipogenic differentiation of A366-treated BM-MSCs was evaluated using oil red staining and fat gene expression analysis. Assessment of the PDT of BM-MSCs and cell-cycle profile showed that inhibition of G9a using low concentrations of A366 didn’t have any significant effect on BM-MSCs proliferative potential. However, the high doses of A366 increased the PDT and induced cell-cycle arrest. Moreover, A366 increased the adipogenic potential of BM-MSCs. Epigenetic regulators such as A366 that have been suggested for controlling cancers can affect BM-MSCs proliferative and differentiation behaviors. These regulators might also be used as a strategy for a more efficient proliferation and differentiation of MSCs to be used in cell therapy, tissue engineering, regeneration and tissue homeostasis. Manuscript profile -
Open Access Article
817 - The Sertoli Cell Efficiency in Spermatogenesis, A Review Study
Mohammad Javid Akbarian Hossein AziziOver 100 million sperm are daily produced by the male reproductive system for the purpose of reproduction and fertility in male gender. During embryonic development, primordial germ cells migrate to the testes and transform into undifferentiated germ cells called sperma MoreOver 100 million sperm are daily produced by the male reproductive system for the purpose of reproduction and fertility in male gender. During embryonic development, primordial germ cells migrate to the testes and transform into undifferentiated germ cells called spermatogonia, which are destined to develop into mature sperm through a process called spermatogenesis. Successful spermatogenesis and thus efficient fertility are dependent upon various factors, including Sertoli cell efficiency. Studies have reported a direct correlation between the morphology of Sertoli and germ cells indicating the importance of these somatic cells inside the spermatogenic tubes. The first structural investigations and possibilities about the function of these cells date back over 150 years when 23-year-old Enrico Sertoli first assessed the structure of these somatic cells. The results of years of research on various functions and effects of these cells have contributed significantly to studies on infertility. This has drawn more attention to the characteristics and mechanisms of physiological action of Sertoli cells, as well as the analysis of disorders related to them so that an effective step can be taken in the treatment of male fertility problems. Manuscript profile -
Open Access Article
818 - Differentiation Effect of Exosomes Derived from Monocytes and Macrophages on Chitosan Alginate Drip Scaffolds
Nasrin Hosseini Javad Baharara Khadijeh Nejad Shahrokhabadi Saeedeh Zafar BalanezhadBone injuries are one of the challenges of medical science which costs a lot of money in the world for the treatment every year. Exosomes are nanovesicles which carry the proteins and genetic material into the target cell, which in turn, induces the proliferation, cell MoreBone injuries are one of the challenges of medical science which costs a lot of money in the world for the treatment every year. Exosomes are nanovesicles which carry the proteins and genetic material into the target cell, which in turn, induces the proliferation, cell survival, and differentiation in the recipient cell. These features make exosomes a proper differentiation factor. This study aimed to investigate the differentiating effect of exosomes derived from the monocytes and macrophages on chitosan alginate drip scaffolds. Chitosan-alginate scaffolds were made by drip method with fat stem cells. Monocytes were cultured, and the supernatant was collected, and the exosomes were collected by the ultracentrifugation. Exosomes were identified by DLS and SEM methods. The samples were treated, and then MTT and DAPI tests were performed. The osteogenic differentiation was examined by alkaline phosphatase and real-time PCR. MTT results showed that the survival rate of differentiated cells with exosomes on days 7, 14, and 21 was increased compared to control group. Moreover, DAPI results showed no cell death in the treatment groups, and the results of the alkaline phosphatase test showed an increase with the control group, and also the results of real-time PCR increased the expression of genes BMP2/6, SMAD4 and differentiation genes Osc and Opn in the treatment group. This study showed that the exosomes derived from the monocytes and macrophages could cause survival and osteogenic differentiation of the fat mesenchymal cells in the chitosan alginate scaffold. Manuscript profile -
Open Access Article
819 - Anti-tumor effects of Silybum marianum essential oil and 5-fluorouracil combination on Hepatocellular carcinoma cells (HepG2)
Mohammad Jaber Masoud Khooy Mohammadreza Salehi Salmi Massoumeh Farasat Hamed MirzaeiThe present study evaluated the efficacy of combining 5-fluorouracil (5-FU) and Silybum marianum essential oils to suppress in vitro Hepatocellular carcinoma (HCC) growth by influencing the Wnt, NF-κB, angiogenesis, apoptosis and autophagy pathways. Silybum marian MoreThe present study evaluated the efficacy of combining 5-fluorouracil (5-FU) and Silybum marianum essential oils to suppress in vitro Hepatocellular carcinoma (HCC) growth by influencing the Wnt, NF-κB, angiogenesis, apoptosis and autophagy pathways. Silybum marianum essential oils were studied alone and in combination with 5-FU in the HepG2 cell-line. The expression of NF-κB and Wnt signaling pathway genes as well as angiogenesis-, apoptosis- and autophagy-associated genes and proteins were evaluated using Western blot and qRT-PCR techniques. Each treatment decreased the viability of HepG2 cells compared with the control group. Moreover, S. marianum essential oils from Khozestan or Isfahan (Sm-K and Sm-I) in combination with 5-FU reduced the migration and invasion of HepG2 cells. Angiogenesis-related proteins i.e. VEGF, COX-2, Bfgf and HIF-1α were significantly reduced. Apoptosis- and autophagy-related proteins i.e. caspase-8, Bax, Bcl-2, Beclin-1, LC3-I, and LC3-II were modulated by each treatment. Each treatment decreased total NF κB (p65) and phospho NF κB (p65) at protein levels. The expression levels of Wnt pathway-related genes were also decreased. Taken together, these findings revealed that S. marianum, either alone or in combination with 5-Fu, could exert anti-tumor effects via modulating autophagy, apoptosis, angiogenesis, NF κB and Wnt signaling pathways. Manuscript profile -
Open Access Article
820 - Examining the Effect of Curcumin on the Nervous Protection and Movement Disorders in Cell Model of Parkinson's Disease induced by 6-HDOP
Mahdieh Azarshab Ramin Hajikhani Mehdi Rahnama Mohammadreza Bigdeli Jalal SolatiParkinson's disease is one of the most common types of the neurodegenerative disease, which is characterized by the movement disorders such as slowness, lack of movement, muscle stiffness, and resting tremor, and hypophonic. The main reason of disease is the destruction MoreParkinson's disease is one of the most common types of the neurodegenerative disease, which is characterized by the movement disorders such as slowness, lack of movement, muscle stiffness, and resting tremor, and hypophonic. The main reason of disease is the destruction of dopaminergic neurons in the Substantia Nigra in the midbrain and a decrease in dopamine concentration in the striatum terminals. In this study, used culture medium was DMEM with FBS, and the cells under study were catecholaminergic cells.6-Hydroxy dopamine toxin was used on cells to create a Parkinson cell model. Curcumin was used as a drug, and MTT, and BT methods were used to count the living cells. This research was designed to study the curcumin effect on Parkinson's disease with cellular model induced by 6-Hydroxy dopamine toxin with reduced inflammation. This study's results showed that using curcumin can increase the antioxidant power and protect the cell from damage caused by reactive oxygen species. Due to the results of MTT, and curcumin treatment due to its anti-inflammatory properties BT test also showed that cellular protection had increased, the death of aminergic catechol cells by 6-hydroxy dopamine toxin was significantly reduced. It shows the antioxidant and anti-inflammatory effects of curcumin on the damage caused by Parkinson's disease and reducing the progression of symptoms. Treatment withcurcumin to be anti-inflammatory can reduce the death of catecholaminergic cells by 6-hydroxy dopamine toxin. Manuscript profile -
Open Access Article
821 - Effect of Red Clover Leaf Extract on Expression of Genes Involved in Follicogenesis and Proliferation of Ovarian Granulosa Cells of NMRI Mice
Farzaneh Rangamiz Javad Baharara Khadijeh ShahrokhabadiInfertility is one of the major medical problems in today’s world. Today, some studies have addressed the effects of phytoestrogenic compounds in the treatment of infertility. Red clover is one of the herbs containing phytoestrogenic compounds. In the present stud MoreInfertility is one of the major medical problems in today’s world. Today, some studies have addressed the effects of phytoestrogenic compounds in the treatment of infertility. Red clover is one of the herbs containing phytoestrogenic compounds. In the present study, the effect of red clover leaf extract on expression of genes involved in follicogenesis and proliferation of granulosa cells in NMRI mice was investigated. In this experimental in vitro study, 30 NMRI 18-20 immature female rats were used. For experiments, follicular granulosa cells were isolated, and in vitro cells were randomly divided into 6 groups.Control (untreated) and experimental groups with concentrations (10, 15, 20, 40, 80 μg/ml) of treated red clover leaf extract and cell viability were evaluated by trypan blue staining and MTT staining. Expression changes of BMP15 and FOXO1 genes were evaluated by Real Time PCR. The results of trypan blue staining and MTT assay showed that cell viability decreased with increasing concentration and time of treatment with clover leaf extract. Moreover, the expression level of BMP15 and FOXO1 genes was significantly increased in the 10 μg/ml red clover leaf extract compared to the control group (p < 0.05). Due to the effect of red clover leaf extract on granulosa cell proliferation and expression of genes involved in follicogenesis, this plant can be considered as a suitable candidate for clinical studies in infertility treatment. Manuscript profile -
Open Access Article
822 - Evaluation of Antioxidant Effect of Cerium Oxide Nanoparticles on Adipose Tissue Derived Mesenchymal Stem Cell Line
Zahra Valipour Marjan Nouri Kazem Parivar Ehsan EhsaniToday, the use of nanoparticles in various fields is increasing. Cerium oxide nanoparticles are one of the types of nanoparticles that are widely used in the nanomedicine as an antioxidant. The specific antioxidant property of cerium oxide nanoparticles made us investig MoreToday, the use of nanoparticles in various fields is increasing. Cerium oxide nanoparticles are one of the types of nanoparticles that are widely used in the nanomedicine as an antioxidant. The specific antioxidant property of cerium oxide nanoparticles made us investigate its antioxidant effect on mesenchymal stem cell line derived from adipose tissue. After preparation and passage of mesenchymal stem cells derived from adipose tissue, these cells were tested for oxidative stress with different concentrations of hydrogen peroxide, which was checked by MTT test, treated and the amount of free radical ROS was measured. Then, the cells were treated with different concentrations of cerium oxide which checked by MTT test and the cell survival investigated by Annexin 5-propidium iodide test by flow cytometry to check apoptosis and finally the results were statistically analyzed. became. The greatest effect of hydrogen peroxide oxidative stress was calculated in 24 h at a concentration of 200 μM and the results of MTT were calculated to determine the IC50 of cerium oxide nanoparticles at a concentration of 100 μM/ml in 24 h. The results showed that this nanoparticle is not only non-toxic for these cells, but also increases their proliferation in certain concentrations. The results of the flow cytometry tests and the evaluation of the effects of cerium oxide nanoparticles also showed that these nanoparticles have a good antioxidant capacity and the survival of cells treated with cerium oxide was similar to the group treated with vitamin C. This shows the effective and beneficial effects of cerium oxide nanoparticles and the potential of this compound in cell regeneration and survival. Based on these results, cerium oxide can be an improving factor in cell proliferation and cell therapy. Manuscript profile -
Open Access Article
823 - Evaluation of the Effects of Methamphetamine Drug on Cell Growth of Stem cells Derived from Uterine Endometrial Tissue of Rats
Zahra Goudarzi Seyyed Ebrahim Hosseini ,Davood Mehrabani Sara HashemiMethamphetamine is a hallucinogenic substance abused by millions of people all around the world. Cellular toxicity in some cell lines is one of the reported effects of this psychoactive substance. Therefore, this study was conducted to investigate the effect of methamph MoreMethamphetamine is a hallucinogenic substance abused by millions of people all around the world. Cellular toxicity in some cell lines is one of the reported effects of this psychoactive substance. Therefore, this study was conducted to investigate the effect of methamphetamine on the growth of adult mesenchymal stem cells extracted from uterine endometrial tissue in rats. In this experimental study, stem cells were extracted from uterine endometrial tissue in rats, and after cultivation, they were investigated in terms of being mesenchymal using flucytometry method and by CD34, CD90 and CD105 markers. In the third passage of cell culture, the effect of methamphetamine toxicity at a concentration of 0.6 mmol was investigated in a 1-8 day period on the growth of mesenchymal stem cells derived from uterine endometrial tissue by formula PDT= T× . Cells isolated from uterine endometrial tissue adhered completely to the floor of the flask 24 hours after being transferred to the cell culture flask. These cells were positive for non-hematopoietic surface marker expression (CD90, CD105) and negative in terms of hematopoietic marker (CD34) expression, so the mesenchymal identity of these cells was confirmed. The results of the cell count test also showed a significant reduction in the growth of cells treated with 0.6 mmol methamphetamine compared to the control group. The results of this study showed that the cells isolated from the uterine endometrial tissue were of the basic mesenchymal type. The results of cell counting revealed that methamphetamine can inhibit growth by inducing the effects of cell toxicity. Manuscript profile -
Open Access Article
824 - Comparative Study of the Urban Fine Dust’s Effects on Blood Cells of Male Rats in Different Cities of Khuzestan Province (Iran)
Najmeh Soleimani Mohammad Reza Dayer Hassan FaridnouriParticles in fine dust have the first rank of carcinogens, making their study necessary. The previous results showed that particles with aerodynamic diameters of 2.5 and 10 micrometers are more permeable and pass through respiratory filters and are the main cause of dam MoreParticles in fine dust have the first rank of carcinogens, making their study necessary. The previous results showed that particles with aerodynamic diameters of 2.5 and 10 micrometers are more permeable and pass through respiratory filters and are the main cause of damage. In this study, the effect of fine particulate matters in different cities of Khuzestan province of Iran on blood cells of male rats was compared. Thirty adult male rats were divided into six equal groups, including control, Ahvaz, Ramhormoz, Andimeshk, Abadan, and Susangerd and were treated for two months. The results of blood cell analysis showed an increase in the number of white blood cells, especially lymphocytes in Ahvaz group, while the volume of platelets was significantly reduced. In most groups, a significant decrease was observed in RDW and the amount of hematocrit in Ramhormoz and Susangerd groups showed a significant increase compared to the control group. Therefore, given the different heavy metals composition, fine dusts have different effects on blood parameters, depending on their amount and duration of exposure. Manuscript profile -
Open Access Article
825 - Study of Biological, compound and Surface Topography if Granule Scaffold Hydroxyapatite/Ostrich Eggshell for Bone Tissue Engineering
Farideh Alahgahi Esmail Fattahi Mohsen Saeedi Mir Mahmoud Mortazavi RoudmianeThis study aimed to investigate the topography surface and ability of this scaffold in combination with the mesenchymal and fibroblast cells. In this regard, several different ratios of hydroxyapatite / ostrich eggshell scaffold were created to determine the surface pro MoreThis study aimed to investigate the topography surface and ability of this scaffold in combination with the mesenchymal and fibroblast cells. In this regard, several different ratios of hydroxyapatite / ostrich eggshell scaffold were created to determine the surface properties and responsiveness to the cells with different types of hydroxyapatite/ostrich eggshell (OsE/HA) combinations (ratios 0-1, 1-2, 1-1, 2-1, 1-0). Natural biomaterials including ostrich eggshells which contain the minerals such as calcium carbonate, play a major role in the fabrication of hard tissue scaffolds. Surface characterization was investigated using SEM and recognizing the scaffold properties by XRD, FTIR. Finally, direct contact (toxicity) test with fibroblast-like cells (L929) was performed to study the cytotoxicity response. After the scaffold toxicity test, the material was ready for in vitro acceptance test, which mesenchymal stem cells isolated from the adipose tissue of New Zealand white rabbit (RADMSCs) which kept with this bioscaffold. This study's results showed that this scaffold has the best biocompatibility and the highest surface lacuna for cell adsorption and attachment with hydroxyapatite / ostrich eggshell. Bioscaffold OsE/HA with the ratio of 1-2 has the best cell attachment among other groups. Natural biomaterials with synthetic materials can promote the bone tissue engineering in many ways. Manuscript profile -
Open Access Article
826 - Evaluation of Antioxidant and Anticancer Properties of Juniperus polycarpos Fruit Extract on MCF7 Breast Cancer Cell
Soheila Moeini Ehsan Karimi Ehsan OskoueianJuniperus polycarpos contains natural bioactive compounds that are used to produce anti-inflammatory and anti-cancer drugs. For extraction, juniper berries were dried for 7 days, then methanol and HCL were added, stirred with a magnetic stirrer, and filtered through Wha MoreJuniperus polycarpos contains natural bioactive compounds that are used to produce anti-inflammatory and anti-cancer drugs. For extraction, juniper berries were dried for 7 days, then methanol and HCL were added, stirred with a magnetic stirrer, and filtered through Whatman paper after distillation. To evaluate the antioxidant activity of juniper fruit extract, the DPPH method was used, and the adsorption rate of free radicals at 517 nm was read. Vitamin c was used as a standard antioxidant to determine the IC50 value of the extract. MCF7 breast cancer cells were cultured, and the cytotoxic effect of the extract was calculated after 48 hours by MTT assay. To determine the toxicity of the extract, the Balb/c mouse model was used. After treatment with doses of 25, 50, and 100 mg/kg, blood samples were taken to evaluate blood cell count changes. Isolation of the liver, kidney, intestine, and spleen tissues for morphological changes and Histology was performed. The antioxidant inhibitory percentage of juniper fruit extract at a 300 μg/ml concentration with DPPH and FRAP methods was 59.47 ± 2.25 and 63.19 ± 2.09%, respectively, and these values were lower than the standard amount of vitamin C used. 66.9 μg/ml of fruit extract was able to inhibit 50% of the growth of breast cancer cells within 48 hours. Blood and tissue cell analysis did not show significant changes in blood cell count and tissue morphological changes. The results showed the cytotoxic effect of the extract on breast cancer cells. On the other hand, the extract did not cause poisoning in the mouse model and did not significantly affect animal tissues and blood cells. . Manuscript profile -
Open Access Article
827 - Investigating the combined effect of endostatin along with endometrial stem cells expressing TSP-1 anti-angiogenic gene on angiogenic induce factors on the treatment of prostate cancer in rats
hossein Attar shakeri Esmail Fattahi Mohammadreza Nowroozi Seyed Ali Momeni Abbas PiryaiProstate cancer is the second leading cause of cancer deaths in men. Androgen ‎deprivation therapy has been identified to induce oxidative stress in prostate cancer, ‎leading to reactivation of androgen receptor (AR) signaling. Thus, antioxidant therapies ‎h MoreProstate cancer is the second leading cause of cancer deaths in men. Androgen ‎deprivation therapy has been identified to induce oxidative stress in prostate cancer, ‎leading to reactivation of androgen receptor (AR) signaling. Thus, antioxidant therapies ‎have gained attention as adjuvants for this cancer. Here, we report for the first time that ‎endostatin along with endometrial stem cells expressing TSP-1 anti-angiogenic gene ‎improved androgen- phenotype and genotype in rats prostate cancer cells.‎‏ ‏Forty male ‎rats (n=8) weighing approximately 95-100 g were purchased from Pasteur Inistitute of ‎Tehran . Animals were suffered to prostate cancer by injecting LNCaP cell line for 12 ‎weeks. Prostate cancer animals were immediately received endostatin for 28 days. ‎Prostate cancer animals were received stem cell containing the Tsp-1 anti-angiogenesis ‎gene. Histological examinations were measured. The levels of IL8 and VEGF serum ‎were assayed.‎‏ ‏In group receiving cells and drug, amount and height of acinus wall folds ‎decreased compared to the patient group and the shape of the vesicles was clear and the ‎epithelial lining were cohesive and regular. The levels of IL8 and VEGF serum were ‎significantly decreased in combination group than to prostate cancer group (P≤0.01). ‎ Manuscript profile -
Open Access Article
828 - The Effect Of Simvastatin On Nitric oxide Synthase Activity In Vascular Endothelial Cell Line (HUVEC)
Seyede Fatemeh Hosseini Tahereh Naji Rahim AhmadiSimvastatin is a 3-hydroxy-3-methylglutaryl coenzyme-A Reductase inhibitor widely used in lowering cholesterol levels.This study was aimed at assessing the effect of simvastatin on the activity of nitric oxide synthase in the vascular endothelial cell line HUVEC. MTT me MoreSimvastatin is a 3-hydroxy-3-methylglutaryl coenzyme-A Reductase inhibitor widely used in lowering cholesterol levels.This study was aimed at assessing the effect of simvastatin on the activity of nitric oxide synthase in the vascular endothelial cell line HUVEC. MTT method was used to evaluate the effect of simvastatin on HUVEC vascular endothelial cell line. The effect of simvastatin on iNOS gene expression in HUVEC vascular endothelial cell line was investigated using real-time PCR technique. The effect of Simvastatin on the activity of endothelial nitric oxide synthase was investigated using grease colorimetry. With increasing Simvastatin concentration, the survival of HUVEC vascular endothelial cells decreased compared to the control group (P≤0.05). In addition, the expression of INOS enzyme gene in the group receiving 55 µl/ml of simvastatin was significantly different and increased compared to the control group (P≤0.05). Simvastatin at concentrations higher than 125 µl/ml simvastatin was not significantly different from the control group. However, at lower concentrations (62, 31, and 16 µl/ml), a significant difference was observed and increased compared to the control group (P≤0.05). Considering the decrease in the level of endothelial nitric oxide synthase and its effects on human diseases, especially cardiovascular diseases, the use of simvastatin can be helpful in patients exposed to disease due to endothelial nitric oxide dysfunction.. Manuscript profile -
Open Access Article
829 - The Effect of Magnetic Water on Growth Factors, Liver Enzymes and Liver Tissue in Female Dormitories
Moluk sadat Sirani Shahla Roozbehani Alireza NazariDue to the scarcity of sweet water resources in the aquaculture industry to increase production, quality parameters of growth and reproduction are among the measures a farmer can take. Using diets and magnetizing fish water will result in shorter market weight and lower MoreDue to the scarcity of sweet water resources in the aquaculture industry to increase production, quality parameters of growth and reproduction are among the measures a farmer can take. Using diets and magnetizing fish water will result in shorter market weight and lower production cost. The present study was aimed at investigating the effect of magnetization with different cell types on the physiology of the effective factors of fish Koi. In this study, the experiment was conducted in four groups and each group with three replications for 90 days using three different strains (0.015, 0.025, and 0.045) and 72 fish of different sexes. During the experimental period of 12 h light and 12 h dark feeding, every 12 h was fed a pellet feed containing 30% protein of 3% fish weight. Repeated effect of magnetic field on water of tanks was performed once every 48 h. No significant differences were observed between the groups in terms of cholesterol analysis and repeated weight changes. The sex hormone parameters and liver enzymes and tissues of liver, kidney, and sexual organs were not significantly different (p < 0.05). The hepatic enzymes SGOT and LDH were highest in the control group (0.025 Tesla) and SGPT and ALP in the control group. The cortisol hormone in the group (0.025 Tesla) and progesterone and testosterone in the group (0.015 Tesla) were significantly different from the other groups and the group (0.045 Tesla) had the least amount of parameters. According to the best results of performance given the magnetism and high quality of food in the experimental groups, it can be concluded that due to cell membrane structures and cell tolerance threshold, the highest tissue degradation was observed in group C that received the highest magnetization (0.045 Tesla). It can be concluded that the effect of different fields on the fish body was confirmed by the results of different fields on the physiology of the fishes tested. Determining the most appropriate field intensity for use in the aquaculture industry that can both increase and reduce aquaculture costs and have no detrimental effect on aquatic physiological factors and factors will require further research and testing.. Manuscript profile -
Open Access Article
830 - Functional evaluation of EZH2 Gene Silencing Effect on β-catenin Marker Expression in YM-1 Squamous Cell Carcinoma Cell Line of Esophageal Cancer
Fatemeh Nourmohammadi Mohammad Mahdi Forghani Fard Vajihe Zarrinpour Mohammad Reza AbbaszadeganEsophageal cancer is the sixth cause of cancer death in the world and the eighth most common cancer in the world. One of the most characteristic features of this cancer is the resistance to chemo-radiotherapy and the high percentage of recurrence in patients. Beta-caten MoreEsophageal cancer is the sixth cause of cancer death in the world and the eighth most common cancer in the world. One of the most characteristic features of this cancer is the resistance to chemo-radiotherapy and the high percentage of recurrence in patients. Beta-catenin marker is one of the main factors of metastasis and invasion in patients. EZH2 gene is a regulatory factor of gene expression and increases the proliferation of tumor cells and maintains the pluripotency of stem cells. EZH2 is aberrantly expressed in a variety of malignant cancers. β-Catenin is a structural component of adherens junctions along with cadherin and the main signaling agent of the Wnt pathway in the nucleus. Aberrant expression of beta-catenin often leads to cancer and metastasis. In this study, the EZH2 gene silencing vector was cloned in Escherichia coli bacteria and then extracted, and the EZH2 gene was silenced in YM-1 esophageal cancer cells. Then RNA extraction and cDNA synthesis were evaluated after confirming EZH2 gene silencing, beta-catenin expression using Real-time PCR technique. Cell migration test was used to check the invasion rate of cells after genetic manipulation. The results showed a decrease in beta-catenin expression in cell lines induced by EZH2 silencing. EZH2 silencing significantly reduced the growth and migration rate of esophageal cancer cells. The results indicate the role of EZH2 gene in regulating beta-catenin gene expression in esophageal squamous cell cancer. Considering that tumor spread is one of the most important factors in the malignancy of ESCC cancer, and on the other hand, these features of esophageal cancer cause premature death of patients due to metastasis and invasion, finding an effective marker in controlling cancer stem cells can be promising for the treatment of ESCC patients. Manuscript profile -
Open Access Article
831 - The Effect of Endometrial Stem Cells with Pomalidomide on Serum Glutathione and Lipids in 6-OHDA Induced Rat Model of Parkinson
Elham Ghasemi deligani Maryam Khosravi Mahmoud Salami Zavareh Ramin Haji KhaniParkinson’s disease is the second most common age-related neurodegenerative disease with no identified effective treatment. The aim of this study was to evaluate the effects of human endometrial stem cells with the anti-inflammatory drug pomalidomide on glutathion MoreParkinson’s disease is the second most common age-related neurodegenerative disease with no identified effective treatment. The aim of this study was to evaluate the effects of human endometrial stem cells with the anti-inflammatory drug pomalidomide on glutathione (GSH) and serum lipids (total cholesterol,TC and low density lipoprotein, LDL)) in the Parkinson’s model in male Wistar rats. Male rats were randomly assigned to five groups (8 animals in each group) including: control, Parkinson’s, and 3 experimental Parkinson’s groups receiving stem cells, pomalidomide, and a combination of stem cells and pomalidomide. Parkinson’s was induced by injection of 6-hydroxy dopamine (concentration 6 μg) in the striatum by stereotaxic method. In the fourth week after surgery, the three experimental groups were treated with 4 mg/kg/daily of pomalidomide, 100,000 stem cells through intranasal route, and a combination of pomalidomide at a dose of 4 mg/kg/daily and 100,000 stem cells. At the end of day 28, blood samples were taken from the groups and factors were measured. The results revealed a significant increase in glutathione among the treated groups compared to the Parkinson’s group. There was also a significant decrease in glutathione in Parkinson’s group compared to the control group. Comparison between Parkinson’s group and the group treated with pomalidomide and endometrial stem cells showed a significant reduction in cholesterol. Moreover, LDL levels showed a significant decrease in LDL levels in the treated groups compared to the Parkinson’s group. Considering the improvement of the measured factors in Parkinson’s rat, allogeneic stem cells can be used as a potential source along with pomalidomide in future research for the treatment of Parkinson’s disease. Manuscript profile -
Open Access Article
832 - The Effect of Curcumin on Testosterone and Liver Enzyme Levels in Varicocele-induced Rats
Mohamad Reza Sadraie Marzieh Tavalaee Mohammad Hosein Nasr-Esfahani Mohsen ForouzanfarVaricocele is one of the most important causes of infertility in men, which in addition to negatively affecting spermatogenesis, can also affect the endocrine system. The link between varicocele and testosterone production is unclear. The liver is one of the most effect MoreVaricocele is one of the most important causes of infertility in men, which in addition to negatively affecting spermatogenesis, can also affect the endocrine system. The link between varicocele and testosterone production is unclear. The liver is one of the most effective organs in the metabolism of substances and hormones. This study aimed to evaluate serum testosterone levels and their association with liver enzymatic changes. Fifty male Wistar rats were divided into 5 groups, including sham control, varicocele induction, varicocele induction (50 mg/kg curcumin), and varicocele induction (100 mg / kg curcumin). After the treatment period, iron (Fe2 +), testosterone, direct bilirubin, total bilirubin and serum concentrations of ALT, and AST were assessed and liver tissue was isolated and examined. Varicocele caused a significant increase in iron levels (p ≤ 0.05) and a non-significant decrease in testosterone levels (p = 0.242) and total bilirubin (T) (p = 0.639). The treatment resulted in a significant decrease in the levels of iron (p = 0.056) and total bilirubin (p = 0.639), as well as a significant increase in testosterone levels (p < 0.05) compared to the varicocele. While the level of direct bilirubin (p ≥ 0.05) in the varicocele showed a significant increase compared to the sham and control. Using curcumin significantly reduced it compared to the varicocele (p = 0.03). Evaluation of ALT (p = 0.762) and AST (p = 0.367) levels did not show a significant difference among the groups. The levels of iron, testosterone, bilirubin, and liver enzymes are negatively affected by varicocele. Curcumin may lessen the harmful effects of varicocele on biochemical components linked with liver tissue in addition to preventing varicocele damage to testicular tissue. In varicocele rats, greater dosages of curcumin may lower the liver enzyme AST. Manuscript profile -
Open Access Article
833 - Anti-glioblastoma Effects of Nano-micelle Curcumin Plus Erlotinib
Ali Bagherian Hamed Mirzaei Nahid Masoudian Bostan RoudiGlioblastoma is one of the most dangerous types of brain cancer, with a high rate of therapy resistance. Apoptosis, angiogenesis, autophagy, NF-κB, and Wnt pathways are just a few of the molecular and cellular processes that play a role in Glioblastoma development MoreGlioblastoma is one of the most dangerous types of brain cancer, with a high rate of therapy resistance. Apoptosis, angiogenesis, autophagy, NF-κB, and Wnt pathways are just a few of the molecular and cellular processes that play a role in Glioblastoma development. The effectiveness of curcumin and Nano-micell curcumin with Erlotinib to suppress Glioblastoma in vitro was investigated in this study.The suppression is carried out by affecting NF-κB and Wnt signaling pathways, angiogenesis inhibition, and autophagy and apoptosis induction. Curcumin and Nano-micelle Curcumin (50 μM) was investigated alone and with Erlotinib (50 μM) in the U87 glioblastoma cells. The expression of Wnt and NF-κB signaling pathways, apoptosis, angiogenesis, and autophagy-related genes and proteins were assessed by qRT-PCR and Western blot. Compared with the control group, all treatments declined the U87 glioblastoma cells viability. Furthermore, Angiogenesis-associated proteins, i.e., Cox-2, VEGF, HIF-1α & bFGF, were remarkably decreased. Each treatment regulated autophagy and apoptosis-associated proteins, i.e., Bax, Beclin 1, caspase 8, Bcl-2, LC3-II, and LC3-I. Total NF κB (p65) and phospho NF. κB (p65) declined by each treatment at protein levels. Expressions of VEGF, cyclin D1, Twist, ZEB, and Wnt pathway-associated genes were also decreased. In general, our findings demonstrated that curcumin and Nano-micelle Curcumin, either alone or in conjunction with Erlotinib, had anti-Glioblastoma effects via modulating a number of processes including apoptosis, autophagy, angiogenesis, Wnt, and NF. κB signaling pathways. Manuscript profile -
Open Access Article
834 - Anti-proliferative effect of Thymoquinone on Raji cell line in Burkitt's lymphoma
Morteza Davoodi Shahriyar Saeediyan Reza Saghiri Zahra Zamani Gholamreza Bakhshi KhanikiMedicinal plants are of interest due to their cheapness, accessibility and better acceptance by patients. One of these plants is black seed (Nigella sativa). In this study, the anti-proliferative effect of thymoquinone, which is the main component of black seed oil, is MoreMedicinal plants are of interest due to their cheapness, accessibility and better acceptance by patients. One of these plants is black seed (Nigella sativa). In this study, the anti-proliferative effect of thymoquinone, which is the main component of black seed oil, is investigated on Raji cells. Raji cells are cancerous B lymphocytes that are seen in the germinal centers of Burkitt's lymphoma. In present study, Raji cells were treated with different dilutions of thymoquinone from 0 to 1000 μg/ml and the percentage of living cells was determined by trypan blue method and MTT test. Also, flow cytometry and Annexin V-FITC/PI kit were used to show the percentage of cells in different stages of growth. The expression of c-Myc gene, which is the most important altered gene in the development of Burkitt's lymphoma, was investigated by Real Time-PCR method. Statistical analysis was also done using SPSS 2020 software. This study showed that thymoquinone can inhibit the growth of Raji cells in a concentration-dependent and time-dependent manner. Thymoquinone, while suppressing the expression of c-Myc gene with a significant percentage, causes Raji cells to enter the stage of programmed death or apoptosis, and has the potential to be used as an adjunctive treatment for Burkitt's lymphoma. Manuscript profile -
Open Access Article
835 - Effect of different levels of dietary vitamin E, sesamin and thymoquinone supplementation on cellular immune challenges, intestinal microbial population, intestinal morphology and MUC2 gene expression in laying Japanese quails
Yaser Rahimian Farshid Kheiri Mostafa FaghaniIn order to investigate the effect of consuming diets supplemented with different levels of vitamin E, sesamin and thymoquinone on cellular immune system challenges, intestinal morphology, intestinal microbial population and MUC2 gene expression in laying Japanese quail MoreIn order to investigate the effect of consuming diets supplemented with different levels of vitamin E, sesamin and thymoquinone on cellular immune system challenges, intestinal morphology, intestinal microbial population and MUC2 gene expression in laying Japanese quails, 210 female Japanese quails aged 85-35 days with 7 experimental treatments including the control group and those consuming vitamin E, thymoquinone and sesamin at levels of 100 and 200 ml.gram/kg of standard feed was used with 5 repetitions and 6 pieces of laying quail in each repetition. At the end of the period (85 days), after killing two quails from each repetition, the relative weight of thymus, spleen and bursa of fabricius and the liver enzymes activity indices such as albumin, alkaline phosphatase (ALP), alanine transaminase (ALT) and aspartate transaminase (AST) were investigated. Dinitrochlorobenzene sensitization challenge test and response to the injection of mitogen phytohemagglutinin into the left wing web were studied. Sampling was done to evaluate the morphology of the intestinal tissue and the microbial flora population of the small intestine. To investigate the expression of MUC2 gene, samples from jejunum were collected and RT-PCR method was performed. The results showed that the consumption of supplemented diets caused a significant increase in the bursa.f relative weight (p ≤ 0.05) and a non-significant improvement of the liver enzyemes activity (p ≥ 0.05). The significant increase of beneficial microbial flora (Lactobacillus) and decrease of the colony population of (Escherichia coli and Salmonella enterica) bacteria in the intestine along with the increase in the surface of the villi and the density of the number of goblet cells indicated the beneficial effects of the active compounds used in improving the health status of quails (p ≤ 0.05). Consuming supplemented diets with levels of vitamin E, sesamin and thymoquinone caused an increase in MUC2 mRNA expression in the intestine. The results showed the benefits of vitamin E, sesamin and thymoquinone consumption on cell mediated mediated immunity, intestinal morphology, intestinal microbial flora and MUC2 mRNA expression in laying Japanese quails. Manuscript profile -
Open Access Article
836 - The Comparison of Sperm Parameters and DNA Damage among Infertile Men with Varicocele and Obesity
Mahshid Elahi Vida Hojati Mahmoud Hashemitabar Mahsa Afrough Hossain PourkargarVaricocele and obesity are common causes of male infertility that negatively influence spermatogenesis. This study aims at investigating sperm parameters and the correlation between the amount of DNA damage in obese patients and patients with varicocele compared with no MoreVaricocele and obesity are common causes of male infertility that negatively influence spermatogenesis. This study aims at investigating sperm parameters and the correlation between the amount of DNA damage in obese patients and patients with varicocele compared with normal subjects. Generally, there were 210 samples, which respectively included 95 semen samples from obese infertile men, 50 semen samples from infertile men with varicocele, and 65 normal men with an age range from 27 to 50 years who met the conditions to be included in the study. It was separated from other samples and the semen was analyzed based on the parameters of the World Health Organization (WHO). The fragility of sperm DNA was evaluated for the mentioned samples. Compared with normal subjects, obese infertile men showed a significant decrease in sperm count, sperm motility, sperm morphology and a significant increase in DNA damage (p < 0.001). Also, a significant negative correlation was observed between DNA Fragmentation Index (DFI) and sperm parameters in obese infertile men, so that with the increase in DFI, other parameters showed a decrease. In obese infertile subjects, DFI had a negative correlation with sperm parameters including number (r = -0.171), movement (r = -0.467) and sperm morphology (r = -0.314). Infertile people with varicocele compared with normal people, a significant decrease in sperm count, sperm motility, sperm morphology and a significant increase in DNA damage were observed. Also, a significant negative correlation was observed between parameters and DFI. In this way, with the increase in DFI, other parameters decreased. In varicocele patients, DFI had a negative correlation with sperm parameters including number (r = -0.466), movement (r = -0.413) and morphology (r = -0.484). The results showed that varicocele and obesity have a negative effect on the health of sperm DNA in addition to reducing the quality of sperm parameters. Also, a significant negative correlation was observed between the amount of DFI and sperm parameters, which shows that these items may adversely influence the process of spermatogenesis. Manuscript profile -
Open Access Article
837 - Investigation of the Effect of Conditioned Media of Mesenchymal Stem Cells Treated with Ascorbic Acid on Proliferative Behavior of Breast Cancer Cells
Fattane Sam daliri Mahmood Talkhabi Narges Toolabi Farnoosh Attari Mousa KehtariBreast cancer is one of the most common types of cancer in women. Today, researchers are looking for new ways to treat cancer. One of the investigated approaches in the field of cancer is the use of stem cells. This study aimed to evaluate the proliferation and survival MoreBreast cancer is one of the most common types of cancer in women. Today, researchers are looking for new ways to treat cancer. One of the investigated approaches in the field of cancer is the use of stem cells. This study aimed to evaluate the proliferation and survival of 4T1 breast cancer cells in the presence of conditioned medium (CM) of mesenchymal stem cells treated with ascorbic acid (AA). Human adipose-derived mesenchymal stem cells (h-ADMSCs) and 4T1 breast cancer cells were used in this study. 4T1 cells were treated with different concentrations of AA and their viability was checked by MTT test. According to the results of previous studies and MTT test, 1 mM concentration was chosen to collect CM from h-ADMSCs. h-ADMSCs were divided into four groups: groups without FBS with and without AA (-FBS/± 1 mM AA) and groups containing 5% FBS with and without AA (5% FBS/± 1 mM AA). Then, the survival rate, colonization potential, cell cycle profile and apoptosis rate of 4T1 cells treated with different CMs were investigated. The results showed that CM in the -FBS/+AA group causes a decrease in the viability and proliferation of 4T1 cells compared to the -FBS/-AA group. Also, CM in the groups with FBS also showed similar results and the FBS/+AA group +5% decreased the survival and cell proliferation of 4T1 cells compared to the FBS/-AA+5% group. Also, CM caused changes in the cell cycle profile of 4T1 cells and their apoptosis rate in the studied groups. According to the results, it seems that ascorbic acid can decrease the survival and proliferation of 4T1 breast cancer cells by affecting the CM compounds obtained from h-ADMSCs. Manuscript profile -
Open Access Article
838 - Evaluation of the Effect of Low Dose of Methamphetamine on the Human Astrocyte Cell Cycle Exposed to Amyloid Beta
Bita Soltanian Marzieh Dehghan Shasaltaneh Gholam Hossein Riazi Nahid MasoudianAstrocytes are the most important and abundant cells helping neurons. They are involved in the neural survival, ionic, and osmotic homeostasis, as well as in the formation of synapses and growth of the axons and dendrites. Activating markers of the cell cycle increased MoreAstrocytes are the most important and abundant cells helping neurons. They are involved in the neural survival, ionic, and osmotic homeostasis, as well as in the formation of synapses and growth of the axons and dendrites. Activating markers of the cell cycle increased in Alzheimer’s disease. Cyclin dependent kinase 1(Cdk1) and cyclin E2 (CE2) are among the cell cycle markers. Besides, methamphetamine in non-toxic dose reduces the automatic division capacity and leads to cell differentiation. In this study, the human astrocytes exposed to amyloid beta (Aβ) and treated with low doses of methamphetamine (METH) and the cell cycle arrest and expression of the Cdk1 and CE2 were assessed in all groups. Five groups were used: 1- The cells expose to Aβ, 2- The cells exposed to METH, 3- The cells exposed to Aβ and then METH, 4- the cells exposed to METH and then Aβ, 5- The control group. Each group was repeated three times. Cdk1 gene expression decreased in group 3, treatment group, but increased in group 4, prevention group. The CE2 gene expression decreased in both groups. Furthermore, the cell cycle arrest in G1, G2, and S were assessed. In the Group 3, treatment group, G2 decreased; but in group 4, prevention group, it increased. Changes in the cell cycle are the early symptoms of Alzheimer’s disease. The low dose of METH can reduce cell cycle activating markers as well as reducing cell division and leading the cells to death. Manuscript profile -
Open Access Article
839 - The Study of the Viability of Human Wharton's Jelly Mesenchymal Stem Cells in Alginate Capsules
Zahra Poursafavi Saeed Abroun Saeid Kaviani Jebeli Nasim Hayati RoudbariStem cells with high proliferative capacity can be isolated from different tissues of the body. These cells originate from the fetal mesoderm and are found in tissues such as bone marrow, fat tissue, amniotic fluid, and Wharton's jelly. In this study, the survival of Wh MoreStem cells with high proliferative capacity can be isolated from different tissues of the body. These cells originate from the fetal mesoderm and are found in tissues such as bone marrow, fat tissue, amniotic fluid, and Wharton's jelly. In this study, the survival of Wharton's jelly human mesenchymal stem cells inside alginate capsules after 7, 14 and 21 days has been investigated. In this experimental study, 10 umbilical cord samples were obtained from pregnant mothers during caesarean section, and the vessels of the umbilical cord samples were isolated. Then it was cultured in DMEM-HG medium containing 10% FBS serum for 5 days. To show the stemness of these cells, CD73, CD34 and CD45 markers were evaluated by flow cytometry technique. After confirmation, the cells were encapsulated in alginate hydrogels. The viability of encapsulated cells was evaluated by trypan blue and MTT. The results showed that the capsules are spherical and have a uniform border and are homogeneously dispersed throughout the capsule. Wharton jelly encapsulation of mesenchymal stem cells did not change their morphology and viability. After 21 days, the survival of the encapsulated cells was maintained. Alginate as a three-dimensional biodegradable scaffold with suitable cell viability can be used as a suitable option for cell therapy and tissue engineering with the property of non-graft rejection. Manuscript profile -
Open Access Article
840 - A Review on Biological Analysis of of Darwin's Evolutionary Theory on the Origin of Cellular Life on Earth
Naeimeh ShibaeiThe origin of cellular life is still unknown. According to Darwin's evolutionary theory that all species of life, due to the process of natural selection, originated from a common ancestor, some have assumed the origin of life to be a random process during which life ev MoreThe origin of cellular life is still unknown. According to Darwin's evolutionary theory that all species of life, due to the process of natural selection, originated from a common ancestor, some have assumed the origin of life to be a random process during which life evolved from non-living materials such as simple organic compounds to has come into existence. The prevailing hypothesis is that the transition from non-living organisms to living organisms was not a single event, but a complex evolutionary process that began after the formation of the Earth after the Big Bang, as a result of the transformation of inorganic molecules into organic molecules. And then with the spontaneous creation of organic molecules with the ability of self-replication, assembly, autocatalysis and then the emergence of cell membrane, nature has been able to choose the best compounds that have the ability to expand on earth and become prokaryotic cells and in the later stages as The ancestors of eukaryotic cells expanded to live on earth. In this research, the different dimensions of the probability of the random emergence of the primary cell are explained and the challenges related to them are examined from different aspects of the sciences of cell biology and genetics. Manuscript profile -
Open Access Article
841 - Investigating the Behavior of MG63 Cells on Polycaprolactone and Polycaprolactone/Collagen 3D Scaffolds for Bone Regeneration
Zahra Ebrahimi Shiva Irani Abdolreza Ardeshirylajimi Ehsan Seyedjafari3D printing of scaffolds at low temperatures is very promising for making artificial bone graft alternatives with more performance than traditional techniques. One of the most promising strategies in bone tissue engineering has focused on the development of biomimetic s More3D printing of scaffolds at low temperatures is very promising for making artificial bone graft alternatives with more performance than traditional techniques. One of the most promising strategies in bone tissue engineering has focused on the development of biomimetic scaffolds. Ceramic-based scaffolds with osteogenic ability and mechanical properties are promising candidates for bone repair. The aim of this study was to adapt the flexibility and increasing the effect of inducing osteogenesis of Polycaprolactone (PCL) scaffold prepared by fused deposition modeling (FDM) method, using the combination of Collagen (COL) as a natural polymer with synthetic polymer and to investigate the behavior of MG63 cells on it. on it. After preparing the scaffold, scanning electron microscope (SEM), energy dispersive X-ray (EDX) and ATR-FTIR spectroscopy were used. After 1,7,14 days, the ossification process of MG63 cells in different treatments was performed using alizarin red staining and alkaline phosphatase activity. The non-toxicity of scaffolds was also evaluated by MTT assay to ensure cell proliferation. From under a microscope, it was found that tissue engineering scaffolds distributed and connected almost rectangular pores evenly. The PCL/COL scaffold showed a significant difference in terms of viability compared to the polycaprolactone scaffold only in the differential medium (P ≤ 0.0001). The results of evaluating ALP activity in PCL/COL scaffolds were significantly higher than uncoated PCL scaffolds and control (P ≤ 0.0001). The results of this study showed that the use of PCL/COL scaffold can be considered a suitable medium for proliferation and differentiation of MG63 cells in bone tissue engineering. Therefore, the PCL/COL composite scaffold prepared by FDM printer can be widely used in bone tissue engineering due to the cell survival by COL. Manuscript profile -
Open Access Article
842 - An Overview of Application of Diferent Nanoparticles in the Treatment of Various Types of Cancer and Investigation of their Cytotoxicity
Elham RostamiChitosan, made of deacetylated of chitin and the amino polysaccharide, is one of the greatest convenient biopolymers, which has large possibilities to be modified for new features of nano-medicine and being used in biomedical fields. Having responsibility of various fea MoreChitosan, made of deacetylated of chitin and the amino polysaccharide, is one of the greatest convenient biopolymers, which has large possibilities to be modified for new features of nano-medicine and being used in biomedical fields. Having responsibility of various features such as cationic nature and controlled drug release, are to the primary amine functional groups in chitosan. There are great properties, such as biocompatibility, biodegradability, loading capacity and an efficient way to avoid undesirable reactions, since the toxicity and side effects of systemic administration are reduced by adjusting Chitosan NPs, they are commonly synthesized as drug carriers. Achieving targeted delivery of drug is due to using peptides, antibodies, aptamer or small molecules. Mentioned methods lower using dosage of adequate drugs. Additionally, they lead the drugs to the targets. Also, the cytotoxicity studies of various nanoparticles and their pharmacokinetic studies have been carried out. The purpose of this review article is to show the importance of the characteristics of antibody-bound, magnetic, pH-sensitive conjugated chitosan nanoparticles in targeted drug delivery and to investigate the effect of these nanoparticles on different types of cancer cells. Manuscript profile -
Open Access Article
843 - The Comparison of 24 and 48 Hours Culture on In vitro Maturation of Oocyte using Menstrual Blood Stem Cells Secretome in Polycystic Ovary
Hilda Rastegari نسیم حیاتی رودباری Somaieh Kazemnejad Soheila AnsaripourThe application of mesenchymal stem cells is a novel approach in regenerative medicine and infertility. Recently, culture enrichment using the secretome obtained from these cells, as well as the optimal time for culture, have been considered in order to improve the resu MoreThe application of mesenchymal stem cells is a novel approach in regenerative medicine and infertility. Recently, culture enrichment using the secretome obtained from these cells, as well as the optimal time for culture, have been considered in order to improve the results of in vitro maturation (IVM), especially in women with polycystic ovaries (PCOS). The purpose of this study is comparing 24 and 48 timing on IVM using secretome of menstrual blood stem cells (MenSCs) along with follicular fluid and melatonin in PCOS women. 400 germinal vesicle oocytes were collected from 100 PCOS patients, as the best candidates for IVM, and randomly divided into four groups: control, secretome, follicular fluid and melatonin. Oocyte maturation was evaluated at 24 and 48 hours. Also, the effect patient’s age on the results of the study was evaluated in the age groups under 30 and over 30 years old in both time periods. Oocyte maturation rate showed a significant increase in 24 hours in the group enriched with secretome compared to the control (p < 0.05). Also, matured oocytes were noticeably higher in melatonin enriched group, in 48 hours, compared to the control (p < 0.001). Moreover, according to our findings, the age of the women did not have a significant effect on the oocyte maturation rate in the 24-hour culture, while in the younger age group, the oocyte maturation rate increased significantly both in secretome and melatonin groups compared to the control group. As a result, the culture time of 24 hours with IVM medium enriched by secretome is the optimal time in order to increase oocyte maturation in PCOS women. Also, the use of melatonin seems to be an effective strategy to improve egg maturation in extended culture times. Manuscript profile -
Open Access Article
844 - A Comparative Study of Nucleostemin Gene Expression in Two-Dimensional Culture Medium and Multicellular Breast Cancer Spheroids
N. Rezapour Vajiheh zarrinpour mohammad kamalabadi farahani amir atashiBreast cancer mortality is mainly due to metastatic disease caused by cancer stem cells. Nucleostemin is a GTP-bound nuclear cofactor that is highly expressed in normal stem cells and tumors and is thought to play an important role in the pathogenesis and metastasis of MoreBreast cancer mortality is mainly due to metastatic disease caused by cancer stem cells. Nucleostemin is a GTP-bound nuclear cofactor that is highly expressed in normal stem cells and tumors and is thought to play an important role in the pathogenesis and metastasis of breast cancer. This study examines the expression level of this gene in a comparison between primary and metastatic tumor cells in two-dimensional and three-dimensional culture conditions. In this study, after creating a mouse model of breast cancer using 4T1 cell line, primary breast cancer cells and brain and lung metastatic tumor cells were isolated and propagated in two-dimensional and three dimensional culture medium. Using real-time PCR reaction, analysis of nucleostemin gene expression was done comparetively between these two culture media. The findings of this experiment showed that the expression of the nucleostemin gene in the metastasis cycle in a two-dimensional culture medium is increased by 6 and 23 times, respectivly, in lung and brain metastatic tumor tissue compared to primary tumor cells. In the three-dimensional culture medium, which was done to enrich cancer stem cells, the expression level of nucleostemin gene in primary tumor cells and brain and lung metastatic cells compared to the two-dimensional culture medium in all three cell groups showed a significant decrease in expression. These findings provide information about nucleostemin gene expression in breast cancer metastatic cascade and 3D culture environment, which deserves further discussion. In this regard, analyzing the molecular properties of metastatic tumor cells, can be used to design targeted treatment strategies in the fight against breast cancer metastasis. Manuscript profile -
Open Access Article
845 - Utilizing the Transposon Vector to Enhance the Expression of Recombinant Erythropoietin in Chinese Hamster Ovary Cells
Reyhane Lohrasbi Seyede Hoda Jazayeri Abbas Daneshipour Zahra Halfinezhad Robabe Mohammadi Parisa Javidzade Amir Amiri-YektaIn pharmaceutical biotechnology and recombinant protein production, due to the low efficacy of inserting the target gene into the host gene genome and its integration into the heterochromatin regions, which leads to the suppression of transcription as well as the instab MoreIn pharmaceutical biotechnology and recombinant protein production, due to the low efficacy of inserting the target gene into the host gene genome and its integration into the heterochromatin regions, which leads to the suppression of transcription as well as the instability of the expression of the desired sequence, achieving cells with highexpression is a challenge. To overcome the limitations transposons, which are mobile genetic elements and have the ability to cut and insert target fragments in certain regions of the genome with the “Cut and Paste” mechanism, are effective. This research aims to evaluate the effect of the PiggyBac transposon vector on the expression level of recombinant Erythropoietin (rEPO) protein and to find a cell line with high expression. First the optimized rEPO sequence based on CHO codon performance was cloned into the pOptiVECTM plasmid. To create the second expression vector, the EPO-IRES-DHFR fragment was inserted into the PB513B-1 plasmid, and then the homogenization steps in both vectors were confirmed using Colony PCR reaction, enzyme digestion, and Sanger sequencing. In order to create a stable cell line, both vectors were separately transfected into CHO DG44 cells and then screened. After confirming the insertion of the vectors into the genome of the target cell, the level of erythropoietin gene expression at the transcript and protein level was checked using qRT-PCR and western blotting tests, respectively, in two cell lines. The Real-Time PCR data indicate a 188-fold increase in erythropoietin gene transcript in the PB513B-1-EPO cell line compared to pOptiVEC-EPO. Additionally, the western blotting test's result confirmed the correct synthesis and secretion of this protein. Analysis of findings in this research revealed that the transposon element significantly increased the expression of the desired gene at the transcriptional level and had could create a cell line with high expression of the target protein. Manuscript profile -
Open Access Article
846 - Inhibition of Breast Cancer Cells by Microvesicles Containing Doxorubicin
Fatemeh Akhavan Attar Shiva Irani mana oloomi Azam Bolhasani Loabat Geranpayeh Fatemeh AtyabiBreast cancer (BC) is the leading cause of cancer-related death among women in the whole world. Therefore, it is necessary to identify new methods for BC treatment. The purpose of this research is to investigate the effect of microvesicles containing doxorubicin (EV-Dox MoreBreast cancer (BC) is the leading cause of cancer-related death among women in the whole world. Therefore, it is necessary to identify new methods for BC treatment. The purpose of this research is to investigate the effect of microvesicles containing doxorubicin (EV-Dox) on the MCF-7 cell line. Mesenchymal stem cells (MSCs) were isolated from human adipose tissue. Microvesicles secreted from MSCs were extracted by ultracentrifugation. The shape and size of microvesicles were assessed by SEM and DLS, respectively. Doxorubicin (Dox) was loaded into microvesicles by sonication method. MCF-7 cells were treated with different concentrations of Dox (2.5, 5, 10, 20, and 40 µM) for 24 and 48 h and EV-Dox (0.625, 1.25, 2.5, 5, and 10 µM) for 48 and 72h. IC50 was determined based on MTT assay. The findings from SEM and DLS showed that the extracted microvesicles are spherical in shape, with a size of about 592.3 nm. MTT results showed that microvesicles aloan had no significant inhibitory effect on MCF-7 cells, and IC50 of Dox and EV-Dox were reported as 2.2 µM and 2.4 µM, respectively. EV-Dox can be a suitable strategy for treating BC because this study showed that the amount of cell death caused by this type of treatment is higher than the treatment with Dox. Also, the survival assay showed that the amount of apoptosis caused by EV-Dox (56.5%) was significantly higher than Dox (43%) ( p < 0.01). Manuscript profile -
Open Access Article
847 - Effect of Stem Cells Containing TSP-1 Gene along with Letrazole on ROS and VEGF Levels in Polycystic Ovary Syndrome Induced by Estradiol Valproate in Female Wistar Rat Model
masoumeh Rahimi maryam bananaj Ramin Hajikhani maryam akhavantaheriPolycystic ovary syndrome (PCOS) is a complex genetic, endocrine and metabolic heterogeneous disorder and the most common endocrine disease and metabolic disorder in children of reproductive age and the most important cause of infertility due to ovulation in women. Ther MorePolycystic ovary syndrome (PCOS) is a complex genetic, endocrine and metabolic heterogeneous disorder and the most common endocrine disease and metabolic disorder in children of reproductive age and the most important cause of infertility due to ovulation in women. There is a direct and close relationship between systemic and local inflammation and the rate of angiogenesis and PCOS. Stem TSP-1 and mice receiving letrazole and mice receiving concomitant TSP-stem cells and letrazazole were categorized and VEGF was measured by Real Time PCR and ROS by ELISA. Wistar female rats with polycystic ovary syndrome (PCOS) had a significant increase in VEGF gene expression and tissue ROS levels compared to the control group, which was significant. The results showed a significant decrease in VEGF gene expression and ROS levels compared with PCOS mice. The highest reduction was observed in letrrazole-receiving mice with TSP-1-containing stem cells compared to the other two treatments in both VEGF and ROS. ROS and VEGF levels are associated with increased ovarian masses, and increased ovarian masses with hypoxia, androgens, insulin, and AMH may increase VEGF levels. Manuscript profile -
Open Access Article
848 - Investigating the Effect of Alpha-ketoglutarate on Survival and Proliferation of Ovarian Cancer Cells
Hossein Beiranvand MAHMOOD TALKHABI Monireh Mahmoodi Ghamartaj HosseinOvarian cancer is the third most common cancer in women. Recent studies have shown that Alpha-ketoglutarate (AKG) has an important therapeutic role in heart and nervous diseases and cancers. In the curreny study, ovarian cancer cells (OVCAR-3 cell line) were obtained fr MoreOvarian cancer is the third most common cancer in women. Recent studies have shown that Alpha-ketoglutarate (AKG) has an important therapeutic role in heart and nervous diseases and cancers. In the curreny study, ovarian cancer cells (OVCAR-3 cell line) were obtained from the University of Tehran at the second passage, and cultured in a complete culture medium (1640 RPMI medium containing 10% FBS and 1% penicillin / streptomycin antibiotic). MTT technique was used to evaluate cellular viability. Also, the doubling time of cell population, colony formation and migration of cells were investigated using appropriate methods. MTT assay showed that treatment of cells with AKG decreases viability in a concentration-dependent manner. Based on the MTT assay results, 120 and 60 μM AKG were selected for the next expreimets. Evaluation of population doubling time showed that both used concentrations significantly reduce cell growth (P<0.05). Colony forming assay showed that 120 and 60 μM of AKG caused a significant decrease in the number of OVCAR-3 colonies (P<0.01). The study of cell migration showed that the treatment of cells with the mentioned concentrations significantly reduces the migration of cells to the scratch area (P<0.01). The results obtained from this study show that AKG reduces the viability of ovarian cancer cells and has anti-proliferative and anti-migratory effects for this cancer cells. It seems that the use of AKG along with other existing treatments can become an helpful approach for better control and treatment of ovarian cancer. Manuscript profile -
Open Access Article
849 - The effect of resistance training on the expression of cell adhesion molecules and RAGE in left ventricular of diabetes rats induced by high-fat diet and STZ
Mohammad Reza Bagheri Afsariehee Abdolali Banaeifar Sajad Arshadi Shahram SohaeilyIntroduction: Diabetic cardiomyopathy (DCM) is a pathophysiological condition that occurs in response to diabetes and leads to heart failure. The purpose of this study was to the effect of resistance training on ICAM-1, VCAM-1 and RAGE gene expression in left ventricula MoreIntroduction: Diabetic cardiomyopathy (DCM) is a pathophysiological condition that occurs in response to diabetes and leads to heart failure. The purpose of this study was to the effect of resistance training on ICAM-1, VCAM-1 and RAGE gene expression in left ventricular in obese rats with type 2 diabetes.Materials & Methods: In this experimental study, 14 male Wistar (220 ± 10 g) diabetic rats induced by high fat diet and STZ injection were randomly divided into resistance or control groups. The training protocol was performed for 6 weeks in 5 sessions per week in the form of 3 sets with 5 repetitions in each set. Rest intervals between sets and repetitions in each set were 90 and 30 seconds, respectively. All rats were dissected 48 h after the last training session. The independent t-test was used to compare variables at a significance level of alpha less than 5 percent.Results: Resistance training did not lead to a significant change in the expression of ICAM-1 (P = 0.237), VCAM-1 (P = 0.295) and RAGE (P = 0.561) compared to the control group. However, it led to a significant decrease in glucose and insulin resistance and a significant increase in serum insulin (P = 0.001).Conclusion: Based on the findings of the present study, resistance training in the absence of changes in the expression of ICAM-1, VCAM-1 and RAGE in left ventricular is associated with the improvement of glycemic profile and insulin resistance in type 2 diabetic rats. Manuscript profile -
Open Access Article
850 - The Effect of Physiological and Environmental Factors on the Number and Distribution of Lymphoid Cells in Kidney of Chacalburnus chalcodies
Vajiheh Bahrpeyma Azam Moshfegh Akram Tehranifard Mahboubeh SetorkiWe aimed to evaluate the effect of physiological and environmental factors on the number and distribution of lymphoid cells in the kidney of Chacalburnus chalcodies. Overall, 84 fish were collected from three sampling stations (sea, river, and estuary) in the southern c MoreWe aimed to evaluate the effect of physiological and environmental factors on the number and distribution of lymphoid cells in the kidney of Chacalburnus chalcodies. Overall, 84 fish were collected from three sampling stations (sea, river, and estuary) in the southern coast of the Caspian Sea, Gilan Province, northern Iran during 12 months. After biometry and determination of age and sex, the kidney was removed and fixed for histological studies. The highest distribution of lymphoid cells was observed during the summer and the lowest during the winter. Linear regression showed a significant correlation between water temperature and lymphoid cell distribution (P<0.05). Pearson correlation test showed a significant positive correlation between lymphoid cells distribution with water, air temperature and dissolved oxygen (P<0.05). Distribution of lymphoid cells had a significant and negative correlation with salinity so that their distribution in the sea was significantly less than the river and estuary. Distribution of lymphoid cells was not statically significant based on fish gender. Distribution of lymphoid cells in kidney Ch. chalcodies had a reverse correlation with age, total length and weight (P<0.01). Manuscript profile -
Open Access Article
851 - Effect of Zaditen and N-acetyl-L-cysteine on Sperm Parameters and Protamine Content in Infertile Men after Varicocelectomy
R. Aghaee-Boroojeni L. Azadi M. Bahadorani M. Tavalaee M.H. Nasr-EsfahaniVaricocele, dilation in pampiniform vein, is known as one of the most common causes of infertility. Decrease in semen quality and increase of mast cells as cells involved in inflammatory and oxidative stress processes can be among main causes of defects in spermatogenes MoreVaricocele, dilation in pampiniform vein, is known as one of the most common causes of infertility. Decrease in semen quality and increase of mast cells as cells involved in inflammatory and oxidative stress processes can be among main causes of defects in spermatogenesis process in related patients. Varicocelectomy, the surgical correction of varicocele, can be with or without drug treatment. Drug application after surgery may be useful for improvement of semen quality. Therefore we aimed to compare the effects of NAC (N-Acetyl cysteine) as an antioxidant and zaditen drug as mast cell blocker on sperm parameters and protamine content after varicocelectomy in individuals with varicocele. In this retrospective study, infertile men who were candidate for varicocelectomy were divided into three groups: control, treatment with a dose of 1 mg per day of zaditen and treatment with a dose of 200 mg of NAC, for 3 months. Sperm parameters and protamine content according to WHO protocols and chromomycin A3-staining respectively were assessed before surgery and 3 months after surgery. Semen parameters (concentration, motility, and morphology) and protamine content were significantly improved after surgery compared to before surgery in both groups that treated whit NAC or Zaditen (P<0.05). Means of sperm parameters were insignificantly higher while percentage of protamine deficiency was insignificantly lower in zaditen group compared to NAC group. Only, percentage of abnormal sperm morphology was significantly lower in zaditen group compared to NAC group. Therefore, both of these drugs are effective in improving sperm parameters and protamin content. Manuscript profile -
Open Access Article
852 - The Effect of Hypoxia Condition on NMRI Mouse Two-cell Embryo Development
D. Bagheri M. Dashtizad M. Daliri E. Hashemi A. Rahim TayefehMany factors can influence the quality of embryos produced in vitro. Oxygen concentration is one of these environment parameters, which its high level can induce the production of reactive oxygen species (ROS) causing detrimental effects on embryo. Pronuclear stage is t MoreMany factors can influence the quality of embryos produced in vitro. Oxygen concentration is one of these environment parameters, which its high level can induce the production of reactive oxygen species (ROS) causing detrimental effects on embryo. Pronuclear stage is the critical time of embryo development, affected by oxygen toxicity more than other stages, so that destructive impacts of oxygen may disappear when in vitro culture initiates from next stages. The present study was conducted to compare the effects of two-oxygen concentration, atmospheric (20% O2) and hypoxic (5% O2) on development of 2-cell embryos to the blastocyst stage. Two-cell embryos were divided randomly into 2 groups including hypoxic and atmospheric groups and were cultured to the blastocyst stage under mentioned conditions. Finally, the blastocysts quality was evaluated in terms of blastocyst formation, hatching rate, cell number and implantation rate after embryo transfer. The results showed a significant increase in the blastocyst formation, hatching and implantation rates in the hypoxic group compared to atmospheric one (P<0.05). Furthermore, total cell number and inner cell mass (ICM)/total cell number were improved in hypoxic group (P<0.05). Our results not only highlighted the fact that hypoxia condition can support embryo development better than atmospheric one, but also showed that contrary to the last reports, destructive effect of oxygen could affect the quality of mouse embryos during all developmental stages. Manuscript profile -
Open Access Article
853 - Protecting Effect Extracts of Satureja bachtiarica and Thymus daenensis Celak against Hepatic Fibrosis Induced by Thioacetamide on Rat
H. Sazegar F. Fadaei Sh. Mashadizadeh N. Ziajahromi F. Sadeghi Samaninowadays, one of the problems of human societies is liver diseases and using chemical drugs with their side effects, causing the researchers change their approaches towards new sources of herbal drugs .The aim of this study was to investigate the effect of Satureja bach Morenowadays, one of the problems of human societies is liver diseases and using chemical drugs with their side effects, causing the researchers change their approaches towards new sources of herbal drugs .The aim of this study was to investigate the effect of Satureja bachtiarica and Thymus daenesis Celak the liver damage is caused by injection thioacetamide. 54 male wistar rats were randomly selected and divided into 9 groups of 6 each groups the (first sahed, second of positive control, third of negative control, fourth, fifth, sixth extracts of Satureja bachtiarica with 5, 10 and 20 miligram per kilogram ,seven , eight and nine extract of Thymus daenensis Celak with 5, 10 and 20 mg/kg extract were given by gavage.Thioacetamide first for three week and twice weekly a rats of 1cc to all groups except the control group were injection then gavage for 14 days savory and thyme extract groups were treated with the extract and the positive drug control group treated with 8 mg/kg capsule sibilinin slap for 14 days.then the blood samples were taken and liver of rats. Histopathologic study suggests that liver lesions compared to the control group is related to the negative control group .Aspartate aminotransferase and alanine aminotransferase well as in the study were assessed and showed that extracts of thyme daenensis has a positive effect on liver fibrosis. By studying the findings, it seems that Flavonoid compounds and phenolic in Thymus daenesis Celak and Satureja bachtiarica can decrease the toxic effects induced By thioacetamide In liver tissue of Mice. Manuscript profile -
Open Access Article
854 - The Therapeutic Effect of Amniotic Mesenchymal Stem Cell Transplantation in Type-1 Diabetes
Soosan Rostam Pur Yadolah Edalat panah Fariba Enayati parvar Reza HaghighiDiabetes mellitus can occur due to insulin deficiency or environmental tissues resistance to insulin with the reduction of insulin secretion. The present study aimed to investigate the therapeutic effect of amniotic mesenchymal stem cell transplantation in the treatment MoreDiabetes mellitus can occur due to insulin deficiency or environmental tissues resistance to insulin with the reduction of insulin secretion. The present study aimed to investigate the therapeutic effect of amniotic mesenchymal stem cell transplantation in the treatment of type 1 diabetes. This study was of experimental type and the animals were divided into four groups including the control or healthy, the diabetic control group, the group receiving cells with the medium, and the group receiving only supernatant soup. Glucose and blood insulin levels and animal weight were studied by ANOVA and t-test during the study. With the first stage of stem cell transplantation, a significant reduction was found in the animal blood glucose of both groups receiving cell and medium (p = 0.004) and the group receiving supernatant soup (p = 0.014) than the control group. Such results were not observed after the second stage. The insulin levels had no statistically significant difference. The present study indicated that the repeated transplantation of Amniotic Mesenchymal stem cells can decrease the blood glucose but increase the blood insulin level and the injection of supernatant soup alone be solely effective as much as the cell transplantation. Manuscript profile -
Open Access Article
855 - The In Vitro Effect of Methyl Tert-Butyl Ether on DNA of Blood Cells (Rutilus caspicus) by Comet Assay
S. Mohammadzadeh Baran A. Mashinchian moradi E. Sharif pour Sh. Jamili P. Ghavam mostafaviMTBE increases oxygen consumption as well as reducing carbon monoxide and air pollution. It is very dynamic in soil, and its movement in water is a function of water movement in soil. MTBE is resistant to biodegradation, its half-life in water is long, its absorption in MoreMTBE increases oxygen consumption as well as reducing carbon monoxide and air pollution. It is very dynamic in soil, and its movement in water is a function of water movement in soil. MTBE is resistant to biodegradation, its half-life in water is long, its absorption in soil particles is weak, having high solubility in water, and being very dynamic. This research was aimed at investigating DNA blood cells of Rutilus caspicus in concentrations of 50, 100 and 150 mg/L MTBE for 7, 14 and 21 days. The mean temperature of water was 19 ± 1°C, water oxygen was 7.6 ± 0.2 mg/l, and salinity was considered zero. 220 R. caspicus with an average body length of 150 ± 30 mm and a weight of 15 ± 3 grams were prepared from Sijawal multiplication workshop located at the Turkmen port in Golestan Province and transferred to the laboratory by means of bags containing water (1/3) and oxygen (2/3). After the adaptation period, 13 fish were placed in 50-liter aquariums. The total number of control aquariums was three, and the number of treatment aquariums was nine. In the first, second and third weeks of the test, three fish were randomly taken from each aquarium and their blood samples were collected. After performing the determined stages, the blood samples of the fish were fixed on the slide and kept in the refrigerator for observation with a fluorescence microscope. In this study, Casp 1.2.3b1 software was used to evaluate the DNA degradation. In this software, several examples of alkaline comet data are extracted in data form. The results of this study showed that there was a significant difference between the control and other treatments in terms of DNA degradation. Furthermore, with increasing exposure time, the amount of DNA damage significantly increased (p < 0.01). Manuscript profile -
Open Access Article
856 - The Effect of Stem Cell Factor and Retinoids in Spermatogonial Cell Differentiation of Testicular Tissue of Obstructive Azoospermia Model Adult Rats
Mahnaz Nasimi Esmaeil Fattahi Sayed Gholamali Jorsaraei Maryam Gholamitabar Tabari Ebrahim Zabihi NeyshabouriRetinoids and stem cell factor play an important role in the stem cells proliferation, survival, and differentiation into sperm. Therefore, in this study, the effect of stem cell factor and retinoids on the proliferation and differentiation of spermatogonial cells in te MoreRetinoids and stem cell factor play an important role in the stem cells proliferation, survival, and differentiation into sperm. Therefore, in this study, the effect of stem cell factor and retinoids on the proliferation and differentiation of spermatogonial cells in testis seminiferous tubules of obstructive azoospermia model adult rats was investigated using the tissue culture system. The testicular tissue fragments were cultured in the culture medium supplement with retinoids or stem cell factor, or a combination of both at the temperature of 34.5 °C and 5% CO2 for 25, 30, and 35 days. Then, the stained tissue sections prepared at the mentioned times were evaluated using PAS and hematoxylin staining methods. The cell counting per unit area was done using ImageJ software, and the statistical analysis was performed by one-way ANOVA and Tukey's post hoc test. The number of spermatogonia, spermatocyte, and Leydig cells increased significantly on day 25, 30 and 35 of culture; additionally, the number of round and elongated spermatid increased significantly on day 35 of culture in the testicular tissue of the obstructive azoospermia compared to the experimental and control groups (p < 0.001). Histological examination of testicular tissue in different culture conditions revealed pathological changes in the epithelialmaking cells. Retinoids played a more effective role on day 35 of culture compared to other factors in maintaining and proliferation of cell lines of the spermatogenesis process. As these factors are not alone the cause of proliferation and differentiation induction, therefore optimizing the culture medium is recommended to achieve adult sperm. Manuscript profile -
Open Access Article
857 - Tradition of Gala Ceremony in Nezami's Eskandarnameh
Jilla Serati Mahdieh AhmadpourAbstract Nezami's Eskandarnameh is of great importance from presenting different traditions and customs. The aim of this investigation is to proceed on one of the most significant traditions of that time i. e. celebration. Nez MoreAbstract Nezami's Eskandarnameh is of great importance from presenting different traditions and customs. The aim of this investigation is to proceed on one of the most significant traditions of that time i. e. celebration. Nezami, in his Sharafnameh, in some cases, presents some customs and traditions related to gala ceremonies of Iranian of that time and in some cases those of other lands with subtle language. In Egbalnameh, the wisest discussions go on between Eskandar and other wise men such as Socrates and Aristotle to purify the treasure of speech. Only in some limited cases, Nezami proceeds on some cases of celebration and hilarities briefly and concisely. Manuscript profile -
Open Access Article
858 - Criticism and Studying of Newly Found Miscellany from the 7th c. A. H.( Kashi Miscellany )
Mojtaba Safarali ZadehAbstract The present article, based on the intra and extra textual documentaries, is to reveal that the writer and author of the present transcription is Ezzoddin Abdolaziz Kashi who was the poet, writer and author of that wor MoreAbstract The present article, based on the intra and extra textual documentaries, is to reveal that the writer and author of the present transcription is Ezzoddin Abdolaziz Kashi who was the poet, writer and author of that work in the late 7th and early 8th c A.H. By investigating the author's poetry in the miscellanies and numerous books of prose and verse, we encountered some of his poems in the Rozatonnazer, the Nozhatolkhater, and in the introduction of the Ghalamiyeh Thsis and we became ensured that this transcript had been written by Ezzoddin Abdolaziz Kashi. A few pages of the beginning and the ending of the book are missing. In this literary miscellany, the works of some famous poets such as Ferdowsi, Daghighi, Assadi Toosi, Khaghani, Hafez, Motanabbi, Abu Novas … and also some unknown poets as Shams Kashi, Sayenaddin Tabrizi, Sadroddin Oshnavaei, Tooreh Poshti, Yusefi and Rortami have been written which are newly found in their genre and unprecedency; and also there are poems with their composers that can be utilized by literary researchers in critical correction of the verses as a dependable source. Manuscript profile -
Open Access Article
859 - بررسی تأثیر طول و گام رزوه بر توزیع تنش در ایمپلنت دندان و استخوان اطراف به کمک روش المان محدود
مسیح فیروزبخت حامد عجبی نائینی مصطفی پیرمرادیان طول عمر ایمپلنت­های درگیر در استخوان تحت تأثیر عوامل بیومکانیکی هستند. کنترل این عوامل، از عوارض مکانیکی که شامل شکستگی پیچ، اجزاء و یا مواد سازنده چهارچوب روکش دندان می­شود جلوگیری می­کند. در این مطالعه، تأثیر تغییرات طول وگام رزوه­های ایمپلنت دن More طول عمر ایمپلنت­های درگیر در استخوان تحت تأثیر عوامل بیومکانیکی هستند. کنترل این عوامل، از عوارض مکانیکی که شامل شکستگی پیچ، اجزاء و یا مواد سازنده چهارچوب روکش دندان می­شود جلوگیری می­کند. در این مطالعه، تأثیر تغییرات طول وگام رزوه­های ایمپلنت دندان بر چگونگی توزیع تنش و بیشینه­ی تنش ون­­میزز، در مجموعه ایمپلنت-اباتمنت و استخوان فک­ به روش المان محدود مورد مطالعه و بررسی قرار می­گیرد. تغییر طول ایمپلنت از مقدار 5/8­ میلی­متر تا 13 میلی­متر و گام رزوه­های ایمپلنت از مقدار 6/0 میلی­متر تا 1 میلی­متر در نظرگرفته می­شود. بیشترین تنش­ها به ترتیب در مجموعه ایمپلنت-اباتمنت، استخوان کورتیکال و استخوان اسفنجی مشاهده می­شود و طول 13 میلی­متر در گام 7/0 میلی­متر به عنوان حالت بهینه معرفی می­گردد. همچنین در این مطالعه نسبت گام به طول بهینه­ای برای ایمپلنت پیشنهاد شده است Manuscript profile -
Open Access Article
860 - An Agglomerate Model for Evaluating the Electrochemical and Hydrodynamic Characteristics of a Proton Exchange Membrane Fuel Cell
Pouya Barnoon Davood Toghraie Babak Mehmandosut Mohammad Ali Fazilati S. Ali Eftekhari -
Open Access Article
861 - Investigation of cell biomechanics and the effect of biomechanical stimuli on cancer and their characteristics
Atefeh Ghorbani Sheyda Shahriari Amir Mohammad Gholami -
Open Access Article
862 - Advancing biomedical, food, and industrial applications through carbon nanomaterials: current status and future perspectives
A. Abdollahpour Ayda Ranjbar Azadeh Asefnejad Bahareh Kamyab Moghadas Yashar Ghaffari David Otasowie Ogbemudia Mehid Taheri -
Open Access Article
863 - Design of Fuzzy Scenario-Based Cognitive Map of Environmental Indicators of Performance Excellence Model (Case Study: Yazd Steel Industries)
omid golshan tafti seyed heidar mirfakhradini davood endelib ardakani habib zare ahmadabadiEconomic activities use and depend on natural resources, and the nature of their processes is such that they potentially pollute the environment. Therefore, environmental evaluation practices in various industries, including the steel industries, should be reviewed. The MoreEconomic activities use and depend on natural resources, and the nature of their processes is such that they potentially pollute the environment. Therefore, environmental evaluation practices in various industries, including the steel industries, should be reviewed. The purpose of this study is to identify the environmental indicators of performance excellence model of Yazd Steel Industries and design the relationships between them through fuzzy cognitive map. This study is applied in terms of purpose and descriptive-survey in terms of type and data collection. At first, with the meta-synthesis approach, 40 articles were reviewed as samples and in order to identify complementary indicators, environmental activists in the steel industry were interviewed, in which 269 environmental indicators, 36 concepts and 9 categories of performance excellence model were identified. In order to collect data and examine the relationship between environmental concepts, industrial and academic experts have completed the questionnaires and with the fuzzy cognitive map technique and FCMapper and Pajek softwares, a linking model between factors and scenario making has been designed. The research findings from the designed fuzzy cognitive map show 157 relationships between 36 concepts, of which six scenarios are obtained in two ways, backward scenario and forward scenario Manuscript profile -
Open Access Article
864 - Designing and Specifying the Indicators of Pattern Excellence in the Strategic Knowledge Management Excellence
mohamadreza hamidizadeh Iraj Soltani maryam gholizadehNowadays most organizations seek for excellence indicators to implement and gain promotion of quality level of services and products and ultimately, value creation for stakeholders. Hence, excellence indicators are considered as an operational framework in the context o MoreNowadays most organizations seek for excellence indicators to implement and gain promotion of quality level of services and products and ultimately, value creation for stakeholders. Hence, excellence indicators are considered as an operational framework in the context of improvement of organizations performance. The objective of this study is specifying the excellence indicators of strategic knowledge management. Thus having used the literature review, fuzzy Delphi approach has been applied to refine and select desired indicators of strategic knowledge management. The used methodology is consisted of four stages and has been refined by Cheng and Lin approach. The population of the study includes 30 industrial and academic experts. In order to analyze the indicators, the initial 52 indicators derived from literature review and five models of excellence model has been selected and by means of fuzzy Delphi method the experts’ ideas and open question in questionnaires has been refined. The result was 80 verified indicators. As a result, by using the indexes extracted, there will be an Excellence route for the organizations and can be achieved as soon as possible in the organization's achievements. Manuscript profile -
Open Access Article
865 - Investigating the Internal Structure of EFQM Excellence Model by Combined Approach Fuzzy Cognitive Mapping and Structural Equation Modeling in Ceramics and Tile Industries of Yazd
Seyed Heidar Mirfakhraddini davood endelib ardakani nasrin jamshidiIn today's competitive and complex world, it is absolutely essential to use a comprehensive and appropriate system such the EFQM excellence model in order to evaluate performance, identify strengths and weaknesses, and improve performance of organizations. Since no orga MoreIn today's competitive and complex world, it is absolutely essential to use a comprehensive and appropriate system such the EFQM excellence model in order to evaluate performance, identify strengths and weaknesses, and improve performance of organizations. Since no organization can reach its goals without paying attention to the relationship between components and the feedback, the purpose of this study is to quantitatively determine and confirm the feedback relationships and loops in EFQM model in ceramics and tile industries of Yazd. In this regard, a combination of two approaches is used fuzzy cognitive mapping and structural equation modeling. In the first step, 7 experts identify 22 relationships among 9 criteria of the EFQM model. In the second step, the accuracy of these relationships is tested by80 senior managers of ceramics and tile industries through two conceptual models. These models are formed based on two EFQM model principles namely the effect of enablers on the results and impact of the results on enablers in feedback, through learning, creativity, and innovation. Determination of the type and intensity of these relationships and quantitative verification helps managers to identify the strengths and weaknesses, introduce continuous improvement projects, and increase self-assessment scores in the above industries. Manuscript profile -
Open Access Article
866 - Model for the credibility of the organization's strategy (audit strategy) to its rating
akbar seyfi amirhassan zarei nima eskandarinia mohammad vasheghaniThe purpose of this study is to provide an organization evaluation model in the process of strategic management. In other words, The proposed model of this study is going to Evaluate the performance of organization’s strategy(validation or verification of or MoreThe purpose of this study is to provide an organization evaluation model in the process of strategic management. In other words, The proposed model of this study is going to Evaluate the performance of organization’s strategy(validation or verification of organizations strategy). The issue ahead is that no comprehensive model which can rate the performance of the organization's strategy or verify the process of collection, implementation and evaluation of the strategy has been developed up to now. There is a vital gap in the issue of strategy verification. The existing models for strategy verification of an organization include some weak points: First of all, they are qualitative; so so they can't present verification result in the form of tangible numbers. Secondly, these models are not comprehensive, and concentrate only on the part of strategy concept. For example, one model evaluates human recourses strategies, and the other model focus on verification of information technology strategy (IT); other concentrates on organization resources as well as creation of competitive advantage. This research discusses an empirical model for assessing the validity of the strategy with the help of library studies, content analysis and interviews with the experts (Delphi method). in order to measure this model validity, it has been implemented in a glass manufacturing company. The results indicate that the proposed model would present necessary standards for quantifying strategy validity. In comparison with the existing models, this model is more comprehensive model covers more dimensions. In this model, verification of competitive advantage and strategic thinking has also been a matter of concern Manuscript profile -
Open Access Article
867 - Studying the Role of Zoroastrians in the Promotion and Excellence of Iranian Culture
shabahang mohajerani aliakbar amini sayed ali mortazavyanThe ancient Iran has had a wide variety of races and minorities since the past. Hence, it is possible to refer to the substantial evidence with regard to the impact of various subcultures on Iranian culture. Thus, the aim of this study is to investigate the role of Zoro MoreThe ancient Iran has had a wide variety of races and minorities since the past. Hence, it is possible to refer to the substantial evidence with regard to the impact of various subcultures on Iranian culture. Thus, the aim of this study is to investigate the role of Zoroastrians in the promotion and excellence of Iranian culture. The premise of this study is that the Zoroastrian activities and practices in the years after the arrival of Islam in Iran to the contemporary period were influenced by the Islamic culture and belief system which contributed to the promotion and excellence of Iranian culture. The data collection technique was desk-and documentary-based research. The descriptive-analytical research method was used. The result of this study suggests that the conformity of the Zoroastrianism practices with cultural and ethical basis of their religion, struggling to preserve and safeguard the national identity, as well as striving for social development, has led to the promotion and excellence of Iranian culture. Finally, the impact of the culture on a nation’s individual and social performance is inevitable. The study of historical procedure and social action of nations confirms this. Manuscript profile -
Open Access Article
868 - Studying the Concerns of Celebrities on Instagram and its Consequences for Fans
Hasan Asadzadeh shahir Taher Roshandel Akbar Nasrollahi Ismail SaadipourIncreasing access to virtual social networks, including Instagram, in Iran has created a unique opportunity for the growth of celebrity culture and their support due to creating an informal media environment and increasing the power of users to share their photos, video MoreIncreasing access to virtual social networks, including Instagram, in Iran has created a unique opportunity for the growth of celebrity culture and their support due to creating an informal media environment and increasing the power of users to share their photos, videos, ideas, emotions, feelings and concerns. In this regard, the aim of this research is to study the concerns of celebrities on Instagram cyberspace and its consequences for fans. The research method used in this research is a qualitative method and the content analysis approach has been used as the operational research method. The participants of the present study include 21 followers of celebrities (with more followers) on the Instagram social network who were selected using a purposive sampling method. In-depth semi-structured interviews were used to collect the data. Also, portability, reliability and verifiability approaches were used to test the validity of the data. The research findings indicate that the concerns of celebrities on Instagram include the representation of social issues, charitable activities, personal branding, and earning the money. The consequences of being the virtual fan of celebrities on Instagram include influencing and changing the people's tastes, influencing people's political interests, exacerbating the social distrust, civil disobedience, and isolating the thought-provoking personalities. Manuscript profile -
Open Access Article
869 - A Comparative Study on the Effect of Different Levels of Carnivorous Chrysomya Larvae Powder on Growth, Feeding and Survival Indicators in Astronotus Ocellatusâs Diet
Mojtaba Ghorbanpour Delavar Reza Changizi Hamed ManouchehriThis Research is conducted to study the effects of using Carnivorous Chrysomya larvae powder as an appropriate alternative to fish meal on the growth indicators of Astronotus Ocellatus and determining the proper replacement amount as totally random designs. The designs MoreThis Research is conducted to study the effects of using Carnivorous Chrysomya larvae powder as an appropriate alternative to fish meal on the growth indicators of Astronotus Ocellatus and determining the proper replacement amount as totally random designs. The designs included four diets(M25, M50, M75, M100) with increasing levels of replacement of 25, 50, 75 and 100% of the insect powder instead of the fish meal for 12 weeks. During the experimental period, biometry of fish and water physico-chemical parameters (dissolved oxygen, temperature and pH) were measured every 15 days. The results showed that diets containing Carnivorous Chrysomya larvae powder had a significant effect on feed conversion ratio (FCR), protein efficiency ratio (PER), percent of weight gain (PWBI), weight gain (WBI), specific growth rate (SGR) and average daily gain (ADG) (P<0.05) and although no significant difference was observed in the survival percentage of the fish with different treatments (P>0.05), the survival was increased by increasing the amount of Carnivorous Chrysomya larvae powder. The best growth and survival results were observed at the replacement treatment of 100% fish meal with Carnivorous Chrysomya larvae powder. Manuscript profile -
Open Access Article
870 - The impact of cobalt in the food of some existing amino acids in Astronatus ocellatus
Hossein Emadi Baba Mokhayer Arezo MahaniFive groups of Astronatus ocellatus were fed with the average mean of 0/8 gr in 90 days in aquariums 30×30×60. The amount of amino acids existing in the muscle of the fish for control treatment and treatment 4 ml/gr was compared. The result showed that there MoreFive groups of Astronatus ocellatus were fed with the average mean of 0/8 gr in 90 days in aquariums 30×30×60. The amount of amino acids existing in the muscle of the fish for control treatment and treatment 4 ml/gr was compared. The result showed that there was a meaningful difference between control treatment and treatment 5 (p<0/05). The amount of Lysine, Methionine, Valine, Phenylalanine, proline, glycine, threonine, glutamic acid was respectively 14/95, 3/14, 9/54, 30/84, 7/01, 11/31, 8/74, 30/18.ml/gr of the muscle of the fish with 4 ml Cobalt chloride in 1 kg of food which was more than the other rations such as treatment ration. Manuscript profile -
Open Access Article
871 - Edge Detection Based On Nearest Neighbor Linear Cellular Automata Rules and Fuzzy Rule Based System
Rahil hosseini -
Open Access Article
872 - Effect of psychocell growth regulator on yield and yield components of wheat under drought stress conditions
علی Noshirvani Sh Mehri حسین Soleymanzade سعید AkbarimehrIn order to investigate the effect of Sykocel foliar application on the yield and yield components of wheat variety (Kohdasht) under drought stress conditions, An experiment was carried out at the station of the agricultural research, education and extension center of A MoreIn order to investigate the effect of Sykocel foliar application on the yield and yield components of wheat variety (Kohdasht) under drought stress conditions, An experiment was carried out at the station of the agricultural research, education and extension center of Ardabil province (Maghan) during the crop year of 2019-2019. The experiment was conducted as a factorial in the form of a randomized complete block design with three replications. The first factor includes psychocel with concentrations of zero (S1), 400 (S2), 800 (S3) and 1200 (S1) mg/liter and drought stress in 3 levels of full irrigation or control (D1), interruption of irrigation in Spikeing (D2) and stopping irrigation were in the seed filling stage (D3). The results showed that with the increase in the concentration of Psychocell, the height of the plant, the number of spikes per plant, the number of seeds per spike, the biological yield, the weight of one thousand seeds and the weight of the stem increased. In the condition of drought stress, the highest number of seeds per spike, spike per plant, 1000 seed weight and stem weight were obtained in the spike stage. In the stress of water shortage in the seed filling stage, the highest plant and stem height was obtained. The lowest number of seeds per spike, spike per plant, plant height, thousand seed weight, leaf weight and stem weight were observed in foliar spraying with a concentration of 0 mg/liter with the control treatment. Psychocel caused a significant increase in all traits compared to the control, which indicates an increase in plant resistance with the use of Psychocel, finally it seems that with foliar spraying with a concentration of 800 mg/liter and drought stress A higher yield can be achieved in the seed filling stage. Manuscript profile -
Open Access Article
873 - Evaluation of sugar beet various cultivars some seed germination and seedling vigor traits by accelerated ageing test
الهه Azadi آیدین Hamidi Sh Shoai فلورا NazariIn order to evaluation of some related to seed germination and seedling vigor traits of six mono germ sugar beet cultivars by accelerated ageing test, a research was conducted as factorial 4×6 (6 cultivars and 4 seed size) by 4 replications based on completely ran MoreIn order to evaluation of some related to seed germination and seedling vigor traits of six mono germ sugar beet cultivars by accelerated ageing test, a research was conducted as factorial 4×6 (6 cultivars and 4 seed size) by 4 replications based on completely randomized design in seed quality analysis laboratory of Seed and Plant Certification and Registration Institute (SPCRI) at Karaj during 2019. Experiment treatments were including, Toucan, Dorotea, Rasta, Sharif (006), Pars (005) and Torbat (004) cultivars and seed width sizes, including 2, 3, 3.25 and 3.5 mm. By standard germination test conducting, after seeds accelerated ageing, final germination and normal seedlings percent, germination rate, germination meantime, coefficient of germination uniformity, seedling dry weight and length and seedling weight and length vigour indices determined. Results revealed that cultivar× seed size interaction effect was significant for all measured traits. The most final germination and normal seedlings percent and belonged to Sharifcultivar3.5 mm size seeds. AlsoTorbatcultivar3.5 mm size seeds had the most germination rate and the lowest mean germination time. Sharif cultivar 2 and 3 mm size seeds had highest coefficient of germination uniformity. The highest seedling dry weight belonged to Rasta and Doreata cultivars 3.5 size seeds. Rasta cultivar 3.5 mm size also had the most seedling length. Pars, Rasta and Toucan cultivars 3.5 mm size seeds had the most seedling weight vigour index and the most seedling length vigour index investigated in 3.5 and 3.2 mm size seeds of Torbat cultivar 3.5 mm size seeds. Generally, Sharif cultivar and 3.5 mm size seeds had more germinability and strong vigour. Manuscript profile -
Open Access Article
874 - The effect of foliar application of cycocel and iron and zinc micronutrient elements on yield and physiological traits of wheat under different irrigation regimes.
سعید Sayfzadeh ناصر Shahsavari سعید AkbarimehrCycocel as a growth regulator and micronutrient elements can moderate the effects of drought stress. This research was conducted in order to investigate the effect of foliar spraying of cycocel and iron and zinc micronutrient elements on the yield and physiological trai MoreCycocel as a growth regulator and micronutrient elements can moderate the effects of drought stress. This research was conducted in order to investigate the effect of foliar spraying of cycocel and iron and zinc micronutrient elements on the yield and physiological traits of wheat pishgam cultivar under drought stress conditions in a private farm in Rabat Karim, Tehran, during the cropping years of 2016-2017 and 2017-2018. The experiment was carried out in the form of split plots in the form of a randomized complete block design in three replications. In this experiment, irrigation at two levels (I1: full irrigation (custom of the region) and I2: interruption of irrigation at the beginning of the spike emergence stage or 51 Zadoks) As the main factor, cycocel at two levels (C1: no use (spraying solution with pure water) and C2: consumption of cycocel at the rate of 0.5 liters per hectare) and foliar application of micronutrient elements in two stages of stem formation and spike emergence at four levels (F1: no use (pure water spray solution), F2: iron foliar application, F3: zinc foliar application, and F4: iron foliar application + zinc (each at a ratio of 3 per thousand) As sub-factors, they were factorial placed in sub-plots. The results of composite data analysis showed that the main effect of irrigation, cycocel foliar application and the interaction effect of irrigation × cycocel at the level of five percent and foliar application of micronutrient elements at the level of one percent was significant on grain yield. The results of comparing the averages of the effect of irrigation and cycocel on grain yield showed that the highest grain yield belonged to the cycocel application treatment under normal irrigation conditions with an average of 7077 kg/ha. The use of cycocel in normal irrigation conditions and also in stress conditions in the spike stage or 51 Zadoks increased grain yield. This increase was more evident under normal irrigation conditions. The results of comparing the averages of the effect of foliar application of micronutrients on grain yield showed that iron + zinc foliar application had the highest grain yield with an average of 5543 kg/ha, and the lowest grain yield belonged to the control treatment with an average of 4638 kg/ha. According to the obtained results, although the drought is causing damage to wheat, but cycocel, iron and Zinc foliar application partially compensated the damage caused by drought stress. Manuscript profile -
Open Access Article
875 - Study on different maize hybrid KSC 704 seed shapes/size germination and vigor by accelerated ageing test
عاطفه Jamalzade ahvazi آیدین Hamidi محمد Nasri In order to study the effect of seed primary germination ability and various seed shapes/size ofhybrid maize (Zea mays L.) single cross KSC 704 some related to germination and vigour traitsby accelerated ageing test, a factorial experiment based on completely rand More In order to study the effect of seed primary germination ability and various seed shapes/size ofhybrid maize (Zea mays L.) single cross KSC 704 some related to germination and vigour traitsby accelerated ageing test, a factorial experiment based on completely randomized design with4 replications was conducted in 2020 in seed quality analysis laboratory of seed and plantcertification and registration institute (SPCRI) at Karaj. Experiment treatments including seedsflat and round shapes and medium sizes having 3 primary germination ability, 92% (abovestandard), 88% (standard) and 85 % (below standard). After accelerated ageing test, standardgermination test was conducted and final germination percent, normal seedlings percent, meangermination time, coefficient of velocity of germination, seedling length, seedling dry weight,seedling length vigor index and seedling weight vigor index determined. Results revealed thatflat seeds and 92 % primary germination ability of studied seed shapes/size seeds had the mostnormal seedlings percent (91 %), mean germination time (1.16-1.18 day) and flat seeds with92% primary germination ability coefficient of velocity of germination (0.865). Also, the mostseedling length belonged to and 92% primary germination ability (30.24) and medium sizeseeds (20.27 cm). Medium size seeds with 92% primary germination ability had the mostseedling dry weight (0.873 gr.) and seeds with 885 and 92% primary germination abilityrespectively had the most seedling length and weight vigor indices (2618 and 70). Thereforebased on this research results revealed that hybrid maize single cross KSC 704 medium size andflat shape standard and above standard primary germination ability seeds for purposes ofgermination ability and seedling vigor had high quality. Manuscript profile -
Open Access Article
876 - Evaluation of Radiological Features in Discospondylitis with Infected Tuberculosis and Brucellosis in German Shepherd Dogs
Kiana Rasouli Siamak AlizadehBackground: Spondylitis is actually vertebral osteomyelitis, and if the infection also involves discs, it is called discospondylitis, which is a complication of diseases such as tuberculosis and Brucellosis. Aims: This study aimed to determine radiological properties of MoreBackground: Spondylitis is actually vertebral osteomyelitis, and if the infection also involves discs, it is called discospondylitis, which is a complication of diseases such as tuberculosis and Brucellosis. Aims: This study aimed to determine radiological properties of discospondylitis due to tuberculosis and brucellosis infections differentially in German Shepherd dogs. Methods: This retrospective cross-sectional study was carried out in affected German Shepherd dogs with chronic discospondylitis due to tuberculosis (TB) and Brucellosis. Data were collected based on clinical and laboratory symptoms, as well as plain radiography and myelography findings. : In total, 13 dogs were studied, of which 9, including 5 males (55.6%) and 4 females (44.4%), were affected with Brucellosis, and 4, including 2 males (50%) and 2 females (50%), were infected with TB. In the diagnostic imaging of the vertebrae, degenerative lesions in affected dogs with TB were significantly more than those affected with brucellosis (with a significant level P=0.026<0.05). Sclerotic lesions were observed in 44.4% of the brucellosis patients and 25% of the TB patients, while lytic lesions were found in less than 50% of brucellosis patients and more than 70% of TB patients. Conclusion: Based on this study, degenerative and lytic lesions in TB cases were more than brucellosis patients; however, sclerotic lesions in TB patients were less than brucellosis patients. The severity of each of these complications and the site of involvement of the vertebrae can be differential features for diagnosing the radiology of TB from Brucellosis in this breed of dogs. Manuscript profile -
Open Access Article
877 - Determination of oxidative stress indicator in dairy cattle with subclinical mastitis
ام البنین GHasemian karik SH Safi The most important and common disease among dairy cows is mastitis and it is still a big challenge for the dairy industry all over the world.Oxidative stress induced by reactive oxygen species(ROS) is a major cause of different diseases especially mastitis in ca More The most important and common disease among dairy cows is mastitis and it is still a big challenge for the dairy industry all over the world.Oxidative stress induced by reactive oxygen species(ROS) is a major cause of different diseases especially mastitis in cattle.there are few studies on the role of ROS in occurrence of subclinical mastitis.the objective of the persent study was to evaluate the changes in plasma malondialdehyde concentrations as a marker of lipid peroxidation of red blood cells and its relationship with somatic cell count(SCC) in milk as the marker of mammary inflammation in cattle.Heparinized blood and milk samples were collected from 45 healthy cows and 45 cows with subclinical mastitis from dairy farms in Tehran province,Iran.No significant difference (p>0.05) was seen between concentrations of malondialdehyde in the studied groups.there was a significant difference (p<0.001) between SCCs in the healthy cows with subclinical mastitis.the concentration of plasma malondialdehyde was higher in cows with subclinical mastitis which indicates mild increase in production of ROS in response to invading pathogens. Manuscript profile -
Open Access Article
878 - Survey on immunogenicity effcacy of a dual vaccine, Combined Rev. 1 and Sheep Pox Vaccine
احسان Gharib Mambini, , M. Gharib Mambini مراد Moradi Maravand, A. Rezaie محسن Mashkuh, مصطفی Kenarkuhi, داراب Abdolahi, , K Amiri محمد Antikchi, افشین Gharib Mambini, N. Soltanisedeh,The diseases, brucellosis and sheep pox, are endemic in Iran and they cause serious losses to the production andhealth of livestock. Susceptible livestock have been vaccinated against these two diseases in appropriate seasonswith a vaccine from Razi Institute vaccine fo MoreThe diseases, brucellosis and sheep pox, are endemic in Iran and they cause serious losses to the production andhealth of livestock. Susceptible livestock have been vaccinated against these two diseases in appropriate seasonswith a vaccine from Razi Institute vaccine for several years. But these diseases, especially the dangerous zoonosisbrucellosis, have not been eradicated after all these years. In this case-control study, 40 lambs within the age rangeof 3.5 - 6 months were selected from a native sheep flock. Vaccines and materials used in this survey were obtainedfrom Razi Institute. This study revealed that the administration of dual vaccine contained of bacterial vaccinesFDRev. 1 with sheep pox vaccine with one injection produced antibody titration as the same as FDRev.1 vaccineseparately. It would be cost beneft to conduct this research for the whole country as it will save lots of money inthe context of staff administration and vaccination. It can also decrease the side effects of multiple vaccinationssuch as stress. Manuscript profile -
Open Access Article
879 - Acinic cell adenocarcinoma in sublingual salivary gland of a cat
سروش Mohit mafi فریبرز Moaeir S.A Razavi مجید Mehri Salivary glands are the most important of the mouth internal secretory.saliva contains many useful enzymes that help in the digestive process.there are for major salinery glands in cats,including the mandibular,sublingual,parotid,and zygomatic galnd. Adeno More Salivary glands are the most important of the mouth internal secretory.saliva contains many useful enzymes that help in the digestive process.there are for major salinery glands in cats,including the mandibular,sublingual,parotid,and zygomatic galnd. Adenocarinomacan affect any of these salivary glands in cats,but the major target of this tomur in cats in the parotid gland.sublingual mass of a cat with clinical sign such as dysphagia,saliva drooling, anorexia and weight loss removed by surgical operation and sent for the histopathological evaluation. in microscopic observation:tumor of a glandular epithelium was seen.acinar cells had been established a solid and adenoid pattern.Malignansy sings,including mitotic formation,hyperchromatism and pleomorphism were clearly visible in nucleus of the neoplastic cells.clinical and histopathological finding reveals an acinic cell adenocarcinoma and in our knowledge,this is the first report of this kind of tumor in salivary gland of a cat. Manuscript profile -
Open Access Article
880 - Changes of somatic cell count, somatic cell score and total bacterial count of raw milk in a dairy herd of Khuzestan province
مهرداد Yadegari پیروز Babamiri sh Nejat M.R Afshar zadeh Bulk milk somatic cell count(SCC), somatic cell score(SCS) and total bacterial count (TBC)are the most important milk health parameters.the aim of this study was to investigate SCC,SCS and TBC in a dairy herd of Khuzestan province.a general linear model(GL More Bulk milk somatic cell count(SCC), somatic cell score(SCS) and total bacterial count (TBC)are the most important milk health parameters.the aim of this study was to investigate SCC,SCS and TBC in a dairy herd of Khuzestan province.a general linear model(GLM) procedure was used for analyzing of data.the result showed effects of year and month are significant on variation of SCC,SCS, and TBC.the highest and lowest SCC and SCS were observed in September and January respectively and the highest and lowest TBC was observed in January and May.the result showed SCC,SCS and TBC increased significantly over time,and it implies the quality of milk decreased in mentioned years.it seems to control this upward movement applying new policies is necessary.in addition,high total bacterial count showed pasteurization is necessary to produce more healthy milk. Manuscript profile -
Open Access Article
881 - The study of Effects of aqueous extract of flaxseed on feta, placental and Hofbauer cell in BALB/c mice on days 3�6 of pregnancy
نرجس Mirab پروین Torabzade منیره MovahediFlaxseed (Linum usitatissimum) is an example of the herbs that has been under investigation of including lignin,fber, α-linolenic acid (ALA), omega-3, phytoestrogen and suggested to be used for the treatment of menopausalhot flashes, depression, decrease blood gluc MoreFlaxseed (Linum usitatissimum) is an example of the herbs that has been under investigation of including lignin,fber, α-linolenic acid (ALA), omega-3, phytoestrogen and suggested to be used for the treatment of menopausalhot flashes, depression, decrease blood glucose levels, blood lipids level. Since estrogen is one of the factorsin pregnancy and the normal concentration of this hormone during pregnancy is essential in the successfulcopletio. According to the high levels of phytoestrogens in flaxseed, the use of this plant in early pregnancy causesdisturbances. That’s why, the effect of aqueous extract of flaxseed on fetal weight, placental weight and the numberof hofbauer cell was determined.Nine groups of Balb/c, each includes ten adult females were selected. The experimental groups received(0.05،0.1،0.2،3.75،7.5،15، 21 mg/kg. b. w) of flaxseed. The control group received no medication, and the shamgroup received only distilled water. The samples were taken at 15 of gestation. Weight of Fetal, placental weightand the number of hofbauer cell measured and analyzed as well. The results were analyzed by Duncan, ANOVAand TUKY test between the control and experimental group. Weight of fetal and placenta in the experimentalgroups showed statistically signifcant decrease comparing with control group (P<0.05). Flaxseed probably causeddecreasing in developmental of fetal and placenta. The increasing number of hofbauer cell confrmed that flaxseedis an external factor. Manuscript profile -
Open Access Article
882 - Comparison optimization Computational model between Cellular Automata and Genetic programming in dynamic response of guyed tower under vibration force
kaveh kumarciIn the telecommunication industry, guyed towers are one of the important structural subsystems. They support a variety of antenna systems at great heights to transmit radio, television and telephone signals over long distance, thus preserving them in events of natural d MoreIn the telecommunication industry, guyed towers are one of the important structural subsystems. They support a variety of antenna systems at great heights to transmit radio, television and telephone signals over long distance, thus preserving them in events of natural disasters such as earthquake is of high priority. Also, domes and transmission stations functions depend on transmitted information by guyed towers. In this paper, seismic behavior of guyed towers are studied. For that, one guyed tower in 9 clusters of guys is studied under earthquake force. This research was accomplished on the base of wind and earthquake forces and tower interaction to these forces. Here, the effect of earthquake force and tower response to seismic events are studied. At first, time history analysis is used in determination of towers vibration natural modes, then, under time- acceleration components of El-Centro earthquake, spectral analysis are accomplished. Analysis outputs are two parameters including frequency and maximum lateral displacement which are provided using ANSYS software. The results are used in comparing two different calculation models: genetic programming and cellular automata. Manuscript profile -
Open Access Article
883 - The effect of mycorrhizal fungi, water stress and year on flower yield and some characteristics of medicinal plant of Borage (Borago officinalis L.) in Yasouj region
Ali RahimiIdentifying the critical time and timing of plant irrigation based on a precise and basic plan is the key to water conservation, improvement of irrigation operations and plant tolerance to water shortage in agriculture. In recent years, vesicular arbuscular mycorrhizal MoreIdentifying the critical time and timing of plant irrigation based on a precise and basic plan is the key to water conservation, improvement of irrigation operations and plant tolerance to water shortage in agriculture. In recent years, vesicular arbuscular mycorrhizal fungi have been used in many plants to deal with dehydration and drought stress. In this regard, an experiment was conducted as split-plot in the form of randomized complete block design with 3 replications in the Yasuj region at years 2015 and 2016. Water stress was considered as the main factor in the form of irrigation after 30, 60, 90, 120 and 150 mm of evaporation from the evaporation pan class A and mycorrhizal fungus was considered as a secondary factor in the form of no application, application of Glomus mosseae and application of Glomus intraradices. The results showed that the interaction of irrigation and mycorrhizal fungi on flower phosphorus, flower yield, biological yield and water use efficiency of Borage was significant. In irrigation levels after 60, 90, 120 and 150 mm of water evaporation from the evaporation pan, the use of mycorrhizal fungi Glomus mosseae and Glomus intraradices compared to the absence of fungi respectively increased the yield of plant flowers (30.04% and 27.35 %), (90.2% and 90.98%), (93.21% and 94.1%) and (81.73% and 78.86%), also, at these levels of irrigation, biological yield and water use efficiency of Borage flower achieved a significant increase in the presence of mycorrhizal fungus, compared to the absence of mycorrhizal fungus application. Application of both strains of mycorrhizal fungus Glomus mosseae and Glomus intraradices in irrigation levels after 90, 120 and 150 mm of water evaporation from the evaporation pan compared to no application of mycorrhizal fungus, respectively, resulted in a significant increase in the harvest index of Borage flower (44.55% and 43.36%), (13.21% and 15.96%) and (5.6% and 5.41%) and flower phosphorus (44.69% and 20.45%), (150% and 125%) and ( 267.74% and 235.48%). Mycorrhizal fungus was able to moderate the negative effects of drought stress and increase the above-mentioned traits in those irrigation levels, and based on the results of this study, irrigation treatment after 90 mm of water evaporation from the evaporation pan + the use of Glomus mosseae mycorrhizal fungi is recommended. Manuscript profile -
Open Access Article
884 - A Comparative Analysis of Digital Audio Encoders: LPC, CELP, and MELP, Evaluating Quality and Complexity of Transmitted Content
Saeed Talati Pouria Etezadifar Mohammad Reza Hassani Ahangar Mahdi MolazadeThis article compares the quality and complexity of LPC, CELP, and MELP standard audio encoders. These standards are based on linear predictive and are used in sound (speech) processing. These standards are powerful high-quality speech coding methods that provide highly MoreThis article compares the quality and complexity of LPC, CELP, and MELP standard audio encoders. These standards are based on linear predictive and are used in sound (speech) processing. These standards are powerful high-quality speech coding methods that provide highly accurate estimates of audio parameters and are widely used in the commercial (mobile) and military (NATO) communications industries. To compare LPC, CELP, and MELP audio encoders in two male and female voice modes and four voice models: quiet, Audio recorded without sound by the microphone, MCE, office, and two noise models 1% and 05% were used. The simulation results show the complexity of MELP is higher than LPC and CELP in terms of both processor and memory requirements. The MELP analyzer requires 72% of its total processing time. This additional memory is, due to the vector quantization tables MELP uses for the linear spectral frequencies (LSFs) and the Fourier magnitude. Also, According to the quality comparison test using the MOS index, MELP has the highest score, followed by CELP and LPC Manuscript profile -
Open Access Article
885 - The Effect of Growth Regulators on Some Photosynthetic Traits and Maintenance of Cell Membrane Structure of Flag Leaf of Two Wheat Cultivars under Rainfed Conditions
Ali Rasaei Saeid Jalali-Honarmand Mohsen Saeidi Mohammad-Eghbal GhobadiWhen the plant is exposed to abiotic stresses, the cell membrane is the first part of the cell to be affected by stress, and the relationships of the many of physiological and biochemical cell of the plant are disrupted. The effect of three growth hormones (3 indoleacet MoreWhen the plant is exposed to abiotic stresses, the cell membrane is the first part of the cell to be affected by stress, and the relationships of the many of physiological and biochemical cell of the plant are disrupted. The effect of three growth hormones (3 indoleacetic acid [IAA], gibberellic acid [GA3] and 6 benzylaminopurine [6 BAP]) with a control (distilled water) was evaluated at booting stage of two wheat cultivars (Rijaw and Azar 2). A factorial experiment using a randomized complete block design (RCBD) with three replications was setup at Campus of Agriculture and Natural Resources, Razi University, Kermanshah, Iran in 2013-14 and 2014-15. Based on the results, the effect of different growth hormones on SPAD, relative water content, Fv/Fm, performance index, leaf cell membrane stability and photosynthetic rate of both cultivars were significant. Among growth hormones, foliar application of Cytokinin and Auxin had the greatest effect on the measured leaf traits and the lowest mean of the traits was obtained in non-spraying treatment (control). Between the two cultivars, Rijaw cultivar was superior to Azar-2. There was also a positive and significant correlation between cell membrane stability and photosynthesis rate, Fv/Fm and performance index. In general, in dryland conditions (water deficiency) with external application of cytokinin in booting stage in superior wheat cultivar (Rijaw) cell membrane stability, relative water content, photosynthetic rate and Fv/Fm were 16, 18, 38 and 45 percent higher than the control, respectively. Manuscript profile -
Open Access Article
886 - The effect of eight weeks of swimming training, cell and laser therapy on the expression of IL-2, IL-10 and STAT-3 genes in testicular tissue in azoospermia model rat.
seyed sasan Hoseyni Habib Asgharpour پروین فرزانگیpurpose: Azoospermia means lack of sperm in semen. One percent of all men and ten percent of infertile men suffer from azoospermia, the purpose of this study is to investigate the effects of eight weeks of swimming training, cell and laser therapy on the expression of I Morepurpose: Azoospermia means lack of sperm in semen. One percent of all men and ten percent of infertile men suffer from azoospermia, the purpose of this study is to investigate the effects of eight weeks of swimming training, cell and laser therapy on the expression of IL-2, IL-10 and STAT-3 genes in testicular tissue. It is azoospermia in rats. Methods: Forty 6- to 8-week-old rats were randomly selected, and then the azoospermia model was induced with Busulfan at a dose of 40 mg in mice. One month after induction of the model, stem cells were transplanted once in the vas deferens at the rate of one million cells per mouse. Then, one week after cell transplantation, a laser with a wavelength of 632.8 nm and a power of 10 mW and energy 3 joules were applied in three repetitions throughout the study period with an interval of once a week, and after improving the effects of surgery, swimming training were performed for 30 minutes and 5 days a week for 8 weeks. Results: The results showed that induction of azoospermia model caused a significant increase in IL-2, IL-10 and STAT-3 genes compared to healthy group rats (P≤0.05). Also, performing the interventional methods of laser therapy, cell therapy and exercise significantly reduced the expression of these genes in the testicular tissue of rats compared to the patient group (P≤0.05). Conclusion: Swimming exercise in combination with cell and laser therapy may help the fertility of azoospermia model rats by reducing testicular tissue inflammation signaling. Manuscript profile -
Open Access Article
887 - The Role of Talent Management and its Triple Strategies Among High School Teachers in Hamadan Province on Organizational Excellence
Dr. Morteza Moradi Rabeah ZandipakIn the competitive environment between organizations, every organization strives to improve the quality of its performance and is moving towards excellence; on the other hand, it is very difficult for organizations to be tempted to achieve their goals of excellence with MoreIn the competitive environment between organizations, every organization strives to improve the quality of its performance and is moving towards excellence; on the other hand, it is very difficult for organizations to be tempted to achieve their goals of excellence without a dedicated and committed workforce. will be. The purpose of the present study is to investigate the role of talent management and its three strategies on organizational efficiency. The purpose of this study is applied, in terms of nature and method, is a descriptive-correlational survey. To test the hypotheses, a questionnaire consisting of 30 questions, adjusted according to the 5-point Likert scale, was used. The statistical population of the study consisted of high school teachers of Hamadan province with more than 6000 people. Sample size was 361 people who were selected as the sample based on Krejcie and Morgan table using Spss software, Cronbach's alpha coefficient and confirmatory factor analysis using Lisrel software The path analysis model was used to analyze the findings. The results show that talent management and its strategies can have a positive and significant impact on the organizational performance directly. Manuscript profile -
Open Access Article
888 - Identifying the Dimensions of Accelerators of Science Production in Scientific Development and Management of Education and Research in Iranian Public Universities: The Grounded Theory Study
Marjan Arab-Rahmatipour Zohreh Mirhosseini Ahmad SaeediProviding appropriate mechanisms to accelerate the production of science that is sufficiently accurate and the required infrastructure has been determined, is always considered an important issue in the country's educational system. The aim of this study was to identify MoreProviding appropriate mechanisms to accelerate the production of science that is sufficiently accurate and the required infrastructure has been determined, is always considered an important issue in the country's educational system. The aim of this study was to identify the dimensions of accelerators of science production in scientific development and management of education and research in Iranian public universities in order to improve the current situation. This applied study is qualitative in terms of data type and grounded theory in terms of research method. The statistical population consisted of 15 faculty members of Iranian public universities, experts in information science and epistemology who had scientific writings and articles in the field and were selected by purposive sampling method. Data collection tool was semi-structured interview and data analysis was performed using MAXQDA software. Based on the research findings, the dimensions and factors affecting the accelerators of science production from the perspective of the above statistical population were identified in 6 dimensions, which include the following: Central phenomenon (qualified educational system, effective research system, comprehensive support system, optimal and efficient financial system); Causal conditions (leadership and management, communications and networks, organizational culture); Strategies (human resource management, infrastructure development, adequate financing); Underlying conditions (legal framework, interdisciplinary communication, interaction with the environment, talent-capturing system, economic issues); Interfering factors (reward and incentive system, position, technology); And consequences (alignment with the environment, improving scientific and organizational performance, human capital development, social and economic development). The results showed that in order to achieve balanced and effective scientific development in the direction of education and research management of public universities, serious and systematic attention to all aspects of science acceleration systems presented in this study is necessary. Manuscript profile -
Open Access Article
889 - Identifying the Managerial Competencies in Future Universities in order to provide an Appropriate Model for Islamic Azad Universities of Iran
Badri Shahtalebi badri shahtalebi mohammadhoseini yarmohamadiyanThe purpose of this study was to identify the dimensions of managerial competencies in future universities in order to provide an appropriate model for Islamic Azad Universities of Iran (AUI). The methodological approach taken in this practical study is a mixed method b MoreThe purpose of this study was to identify the dimensions of managerial competencies in future universities in order to provide an appropriate model for Islamic Azad Universities of Iran (AUI). The methodological approach taken in this practical study is a mixed method based on sequential exploratory strategy. The qualitative phase was done by using thematic analysis based on inductive approach, the statistical population was all articles and theses listed in international databases in the field of managers’ competencies in future between 2000-2017. A total of 134 samples were chosen by using purposeful criterion-based sampling and with this number, theoretical saturation was achieved. 100 primary themes were found and the content validity checked in two ways of qualitative and quantitative. The reliability was estimated 0.85 by Holistic coefficient. The themes network was drawn up including 3 global Themes, 9 organizing themes and 29 basic themes. In the quantitative phase the statistical population was all 11554 faculty members of the comprehensive universities in AUI in 17 geographical zones in 2016-2017, and then by using Cochran formula, 373 people were chosen via non-random sampling: availability sampling as a sample size. The 100-item researcher-made questionnaire was based on 5-point Likert scale. Face and content validity were confirmed by experts, and construct validity was assessed by using factor analysis and the reliability of questionnaire was estimated by using Cronbach's alpha which were higher than 0.75 that showed high internal correlations between basic themes. In order to analyze the data, the confirmatory factor analysis method and structural equation modeling of covariance axis were used. According to the Chi-square, comparative fit indices, parsimonious fit indices and Hoelter’s fit indices the research model was perfect fit. Among them, value creator, excellence-oriented and driver force with factor load of 0.97, 0.94 and 0.92 had the most explanatory effect respectively. Manuscript profile -
Open Access Article
890 - Providing a Model For servant leadership For the Excellence of Education Organization in Tehran Province
Jafar Askary Dafe Mohammad Salehi Reza UosefiThe purpose of this study was to present a model of servant leadership style for education excellence in Tehran province. The research method was applied-foundational in terms of purpose, and combined exploratory in terms of the research method. The statistical populati MoreThe purpose of this study was to present a model of servant leadership style for education excellence in Tehran province. The research method was applied-foundational in terms of purpose, and combined exploratory in terms of the research method. The statistical population of the research in the qualitative part included academic experts and education officials. Also, the statistical population in the quantitative part of the research included all the bosses and deputies and officials of the education and training departments of Tehran schools. Among them, 780 people were selected using Cochran formula and multi-stage random cluster sampling method. In this study, the library method, semi-structured interview (qualitative part) and researcher-made questionnaire (quantitative part) were used to collect data. Validity and reliability of the tools were approved. Content analysis was used to analyze the qualitative data of the research. Structural equation modeling, exploratory factor analysis and one-sample t-test were used in the quantitative part. The results showed that the components of servant leadership including serving, modesty and humility, reliability, altruism, interaction, work-life balance, prosperity and ethics, and components of organizational excellence including leadership, policy; staff; participation; processes; customer outcomes; employee outcomes; social outcomes; key outcomes based on performance; learning; innovation; productivity; were identified. Manuscript profile -
Open Access Article
891 - Identifying Dimensions of Organizational Excellence with Emphasis on EFQM Model in Islamic Azad University
Mohammad Reza Imani Geleh Pordesari Fattah Nazem samad karimzadehThe purpose of this study was to Identifying dimensions of organizational excellence with emphasis on EFQM model in Islamic Azad University. The research method was fundamental in terms of purpose and in terms of data type it was a combination (qualitative-quantitative) MoreThe purpose of this study was to Identifying dimensions of organizational excellence with emphasis on EFQM model in Islamic Azad University. The research method was fundamental in terms of purpose and in terms of data type it was a combination (qualitative-quantitative) one. The statistical population of the qualitative research part included academic experts and managers of the Central Organization of Islamic Azad University. In the quantitative part, all the staff of the Central Organization of Islamic Azad University were 1535 people participated in the study. The sample size in the qualitative part was determined using the theoretical principle of saturation. Twenty people were selected by purposeful method. In the quantitative part, 320 people were selected as the sample using Cochran's formula and by random sampling method. The data collection instrument was a semi-structured interview in the qualitative part. In a quantitative part, a researcher-made questionnaire which had 97 organizational excellence questions with an emphasis on EFQM. The method of data analysis in qualitative part, was data based; also, in the quantitative part, descriptive statistics methods were used and in the inferential part of the factor analysis methods exploration were used. The results showed that the components of organizational excellence in Islamic Azad University, with emphasis on the model of European Quality Management Foundation, including learning, employee productivity, customer results, employee innovation, leadership, policy and strategy, partnerships and resources, processes, key performance results, employees, staff results and Community result were identified. Manuscript profile -
Open Access Article
892 - Provide Damage Model of the Technical Education System Based on the Organizational Excellence Model by Identifying the EFQM Indicators and Components in Empowerment and Results
pari hemmati mahmud safari معصومه اولادیانThe purpose of this study was to investigate the pathology of a professional technical education system based on the EFQM organizational excellence model. In this research, in order to better understand the issue in terms of organizational excellence, as well as to iden MoreThe purpose of this study was to investigate the pathology of a professional technical education system based on the EFQM organizational excellence model. In this research, in order to better understand the issue in terms of organizational excellence, as well as to identify its dimensions and components, and identify the factors affecting it, through in-depth and exploratory interviews with individual key stakeholders and selected experts Technical and professional staffs including heads of departments and deputies of the organization, human resources and education departments, heads of provincial departments and managers and teaching staff of formal education and training institutes with more than 5 years of experience in the college of technical and professional staff and academic experts. These people were chosen purposefully. The necessary qualitative data were collected and analyzed using content analysis method as research technique, concepts, categories and main and secondary factors. These concepts, factors and categories are the basis for developing a tool (questionnaire) to identify the dimensions and components of organizational excellence among the employees of the technical and professional organization of Tehran. In order to ensure the validity of the qualitative part of the research, the valuable ideas of the professors familiar with this field and the university experts who were well-known in this field were used. The reliability of the retest and the intra-subject agreement method were used to calculate the reliability of the interviews conducted Manuscript profile -
Open Access Article
893 - Determining Structural Relationships and Ranking of Factors Affecting Entrepreneurship Education in Knowledge-Based Businesses in Accelerators Based in Academic Growth Centers
Tahereh Abuie Samereh Shojaeei Fereydoon Azma Hassan Ali AghajaniThe purpose of this study was to determine and rank the factors affecting entrepreneurship education of knowledge-based businesses in accelerators based in academic growth centers. The purpose of this study is applied and developmental and it is a descriptive survey and MoreThe purpose of this study was to determine and rank the factors affecting entrepreneurship education of knowledge-based businesses in accelerators based in academic growth centers. The purpose of this study is applied and developmental and it is a descriptive survey and qualitative research. The statistical population consisted of specialists, experts and experts in education and entrepreneurship in the country. Using non-random and purposive sampling method, this study was conducted in year 1398. Data collection was done by library and field research. Semi-structured interviewing tool was used in field study, data analysis in Delphi method. Fuzzy was done Factor analysis was confirmed to rank the factors influencing entrepreneurship education hierarchical method is used. The results showed that industry relevance indexes, facilities and equipment, content of training courses, training courses, processes and processes, structural factors, development factors, financial system, behavioral factors, research system and graduates' activities respectively in entrepreneurship training centers. Academic growth is a priority. Based on the research findings, it can be concluded that appropriate entrepreneurship education requires Developing an Appropriate Approach to University-Industry Relationships supportive policies for start-up students, updated labels, an entrepreneurial approach to teaching, research, culture, and entrepreneurship. Change themselves according to the need and lack of environmental certainty Manuscript profile -
Open Access Article
894 - Investigating the Effective Factors of Elementary School Management Excellence Model in District 15 of Tehran
Baharak Shirzad Kebria Gholam Ali Shabani Nejad parastoo khosraviThe purpose of this study was to determine the effective factors of School Management Excellence Model of District 15 and determine the priority and delay of effective factors of School Management Excellence Model of District 15 based on Organizational Excellence Model MoreThe purpose of this study was to determine the effective factors of School Management Excellence Model of District 15 and determine the priority and delay of effective factors of School Management Excellence Model of District 15 based on Organizational Excellence Model in 1397. This research was conducted using descriptive survey method. The sample size was selected from the population of 204 using Cochran formula. The research tool of this study, which measures the advanced variables questionnaire, consists of 10 criteria, each of which has guidance and objective points that are adjusted based on the characteristics of education. The validity of the questionnaire was used by professors and experts and Cronbach's alpha test was used for reliability of the questionnaire with a value of 0.93. Data from the sample size were analyzed using one-sample t-test. The following scores were obtained for teaching and learning (78%), first degree development of parent and community institutions (72%), second degree development, and human resources development (70%) and third degree, and Executive and administrative affairs (70%), fourth degree, extracurricular activities (69%), fifth degree, and action plan development (67%), sixth and creativity (66%), seventh degree, motivational growth system (60%). Eighth Grade Health, Prevention and Safety Education (34%) is ninth, and the lowest score is in the area of school administration results by student participation (30%). Manuscript profile -
Open Access Article
895 - A Survey on Excellence Management and Component Factors of it in Private High Schools of Tehran Education
hamid haft javaherian Seyed farhad Eftekharzade Abbas KhorshidiThe major goal of this research is A Survey on Excellence Management and Component Factors of it in Private High Schools of Tehran Education. The research method is a cross-sectional survey. The statistical population contains 12,000 from all of the administrator, staff MoreThe major goal of this research is A Survey on Excellence Management and Component Factors of it in Private High Schools of Tehran Education. The research method is a cross-sectional survey. The statistical population contains 12,000 from all of the administrator, staff, expert and specialist in the schools of Tehran which have certificate of license or upper of it. The volume of research sample consist of 375 member of school employments. The tools of data collection is questionnaire that contain 174 question which extract from 2013 EFQM excellence model. 70 people were randomly selected. The reliability of the questionnaire for the 9 factors was calculated using Cronbach's alpha coefficients. To analyze the data in the inferential statistics section, the confirmatory factor analysis test (using LISREL software) was used. The results showed that the standard parameter values t >2 for each of these factors were related to their factor load on the latent variable. Manuscript profile -
Open Access Article
896 - The Impact of Organizational Excellence and Development on Human Resource Development (Case Study: Meteorological Organization)
Hajar Shiri Kamran Mohammadkhani Babak NasiriThe purpose of this study was to investigate the impact of organizational excellence and Maturity on human resource development. The present study is applied in nature by descriptive-survey method. The statistical population consisted of 400 members, including fac MoreThe purpose of this study was to investigate the impact of organizational excellence and Maturity on human resource development. The present study is applied in nature by descriptive-survey method. The statistical population consisted of 400 members, including faculty members of Tehran Free and State Universities and Meteorological Organization staff. The sample was selected using Morgan table. Research tools included library studies and questionnaires. The research questionnaire was a combination of the researcher-made questionnaire of human resources developed by Flint et al. (2002), the Strauss and Corbin Questionnaire, and the standard component model validation questionnaire. The validity and reliability of the instruments were assessed and confirmed. Data analysis was performed in two parts: descriptive and inferential (including software Structural Equation Method (PLS) and single group t test). The results of this study showed that maturity and excellence have an impact on the development of human resources in the Iranian Meteorological Organization. Manuscript profile -
Open Access Article
897 - National and Patriotic functions in Ra’di Azarakhshi’s poetry using epic approach
Faramarz Ahmadi Mehdi Mahoozi Mahmoud TavoosiIn every society there exists a kind of collective consciousness known as national awareness and it is expressed in Persian literature as national patriotic theme. The purpose of this article is to discuss and evaluate Gholam Ali Ra’di Azarakhshi’s vie MoreIn every society there exists a kind of collective consciousness known as national awareness and it is expressed in Persian literature as national patriotic theme. The purpose of this article is to discuss and evaluate Gholam Ali Ra’di Azarakhshi’s viewpoints regarding Persian language, culture, civilization, and social values of Iran and to study and analyze national and patriotic themes in his compositions. Furthermore, the application of contemporary epic literature in his compositions is studied. Using descriptive analytic and library approach the attempt is made in this article to study themes such as patriotism, antagonism towards enemy, also to study national and historical characters. The results obtained show that Ra’di paid special attention towards contemporary epic functions such as anti-colonialism, national identity and language, preservation of independence and territorial integrity. His attitude towards the concept of homeland and patriotism is to a large extent different from that of other poets. The vastness of his thoughts in celebrating national and historical figures spans past till present characters. Manuscript profile -
Open Access Article
898 - Mowlana’s cry, Masnavi’s gem
Ali SanayeiThis article aims at discussing the main concepts in Masnavi. An analysis of the content is also offered from the point of view of Molla Sadra’s three principle and Mowlana’s Gnosticism.This article aims at discussing the main concepts in Masnavi. An analysis of the content is also offered from the point of view of Molla Sadra’s three principle and Mowlana’s Gnosticism. Manuscript profile -
Open Access Article
899 - Preconcentration and Determination of Theophylline in Water Samples using Magnetic Nano-Cellulose with Dispersive Solid Phase Extraction
Parastoo Molaei ali moghimi Shahin Ahmadi seyedali sobhanianTheophylline (1,3-dimethyl-2,3,6,7-tetrahydro-1-hydrogen-purine-6,2-dione) is a bronchodilator drug used in the treatment of asthma and chronic obstructive pulmonary disease (COPD). Due to the narrow therapeutic strip of this drug, it is important to measure its blood l MoreTheophylline (1,3-dimethyl-2,3,6,7-tetrahydro-1-hydrogen-purine-6,2-dione) is a bronchodilator drug used in the treatment of asthma and chronic obstructive pulmonary disease (COPD). Due to the narrow therapeutic strip of this drug, it is important to measure its blood level.To achieve a simple, safe and sensitive method based on dispersive solid phase extraction (DSPE) using magnetite nanoparticles covered with nanocellulose and beta-cyclodextrin for preconcentration and measurement of theophylline in aqueous samples and its validation, this method was used. In this research, variables affecting the extraction such as pH, ionic strength, and amount of adsorbent, temperature, time, limit volume and type of solvent were optimized. After extraction, the adsorbent was easily separated from the aqueous sample using an external magnetic field without filtration or centrifugation. The results showed that optimum conditions were obtained with pH=5, 1 mg of sodium chloride, 0.2 g of adsorbent with a capacity of 0.53 mg/g, temperature of 40 degrees Celsius, 20 minutes of contact between the adsorbent and the sample and 5 mL of methanol as the desorption solvent. In optimal conditions, the suitable concentration factor is 12, low detection limit (0.17 mg/L), wide linear range and in accordance with the therapeutic strip of the drug (5-50 mg/L), good correlation coefficient (R2=0.9991) and good accuracy (RSD=1.03%) was obtained.Urine sample was used to validate the above method. Also, it was found that the proposed method is suitable, efficient and usable for measuring of theophylline. Manuscript profile -
Open Access Article
900 - Recent Advances in the Development of Quantum Materials for the Construction of Solar Cells: A Mini Review
O. Ashkani B. Abedi-Ravan Y. YarahmadiSolar cells are one of the most important equipment’s in the field of clean and novel energy that can be used without chemical pollution. Solar cells are very valuable equipment that by using them, in addition to reducing environmental pollution, can benefit from clean MoreSolar cells are one of the most important equipment’s in the field of clean and novel energy that can be used without chemical pollution. Solar cells are very valuable equipment that by using them, in addition to reducing environmental pollution, can benefit from clean energy. Solar cells are generally used in various industries, including aerospace, clean energy and even transportation. In the meantime, increasing the efficiency of solar cells is of great importance, and the development of quantum science has made a significant contribution to this issue. The use of quantum dots containing different materials such as graphene, carbon, gallium, lead and similar materials can increase the efficiency of solar cells from 3 to more than 50% on average. Also, the power conversion efficiency in solar cells developed with quantum dot technology reports from 1 to more than 15% improvements compared to conventional solar cells. In this research, to summarize the latest achievements in this field, an overview of the importance of quantum dots about the development of solar cells has been done. Manuscript profile -
Open Access Article
901 - Examining the verdict of simulation therapy from the point of view of Shia and Hanafi jurisprudents
sayed askari Hosseini Moghadam alireza safari عباس عرب خزائلی Sayed Ali Hashmi Khan AbbasiAmong the evolving human achievements are therapeutic simulation and the technique of obtaining stem cells from the embryo. In this technology, embryos are created in the laboratory to use the stem cells of those embryos to treat diseases. In the meantime, obtaining ste MoreAmong the evolving human achievements are therapeutic simulation and the technique of obtaining stem cells from the embryo. In this technology, embryos are created in the laboratory to use the stem cells of those embryos to treat diseases. In the meantime, obtaining stem cells from laboratory embryos, which is the basis of therapeutic simulation, is desirable in Islamic jurisprudence for some and rejected by others. Accordingly, in this study, we intend to use the Islamic rules in a comparative comparison to analyze and analyze therapeutic simulation in terms of the jurisprudence of Islamic religions. The research method of this article is descriptive analysis. Research information has also been collected in a library. Findings show that famous Shiite and Sunni jurists agree in this regard and consider the use of this treatment technique as a step towards a deeper understanding of the hidden traditions of the universe and based on the principle of immorality and permission, accept it according to the principles. And they consider the claim of impermissibility to be justified. Manuscript profile
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