Evaluation Of the Effects Of Different Concentrations Of Aloe veraExtract on the Proliferation Of Uterus Cervical Cancer Cells(Hela)Of Humans

Subject Areas :

Elahe Ebrahimi ¹ , Masoud Parsania ² , Hamid Hosseini dost ³

1 - گروه میکروبیولوژی، دانشکده علوم و فن آوری‌های نوین، واحد علوم دارویی، دانشگاه آزاد اسلامی، تهران. ایران.
2 - استادیار گروه میکروبیولوژی، واحد تهران پزشکی، دانشگاه آزاد اسلامی، تهران. ایران
3 - استاد گروه میکروبیولوژی، واحد علوم دارویی، دانشگاه آزاد اسلامی، تهران. ایران.

Received: 2015-06-28 Accepted : 2018-08-04 Published : 2015-07-23

Keywords: human, Hela Cell Culture, tissue culture, Tripan Blue and MTT, Aloe veraExtractions, Cytotoxicity,

Abstract :

Inroduction and Objective: Cervical cancer is the second most common cancer in womenHigh incidence ofcerviccancer and the side effects of the treatments with synthetic chemical compounds demonstrated that hazards are immense.Considering the side effects, treatment with extracts of plants such as Aloe vera have proved to be reducing the levels of side effects and can bemuch cheaper alternative. So, anti cancer properties of the extracts of Aloe vera against the Hela cells of humanwas evaluated in tissue culture, in this study.Material and Methods:After gatheringand confirmthe desiredplant species.Extractionwas performed bymacerationThe toxicity effects of different concentrations 16,17,18,19, 20 and 21 mg/ml of extract of Aloe veraon the Hela cells of human, were evaluated using Trypan blue and MTT methods,on 24, 48 and 72 hours after exposure to a mediumcontaining 1serum and extractResults: 20 mg/ml concentration ofAloe veraextract was toxical effects on Hela cells of human based on the results obtained, it was concluded that extracts of Aloe verainhibit the proliferation of Hela cells of human