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Open Access Article
1 - Fabrication of Au/ZnO/MWCNTs electrode and its characterization for electrochemical cholesterol biosensor
Davood Ghanei Agh Kaariz Elham Darabi Seyed Mohammad Elahi -
Open Access Article
2 - Comparison of three different methods for detection of corn and sunflower oils in adulterated sesame oil
Peyman Mahasti Shotorbani Hassan Hamedi Melika Zandi Maryam Fahimdanesh -
Open Access Article
3 - Evaluation of the effect of different doses of folic acid supplementation on serum lipid profiles in experimental obstructive cholestasis in rat
Mohammadian, Z. *, Eidi, A. , Mortazavi, P. , Tavangar, SM. , Asghari, A. .Hypercholesterolemia was the result of the cholestasis and failure of cholesterol and bile saltsclearance through the bile duct.The main proposal of this study is to investigate the effect offolic acid supplementation on serum lipids composition in a rat model of choles MoreHypercholesterolemia was the result of the cholestasis and failure of cholesterol and bile saltsclearance through the bile duct.The main proposal of this study is to investigate the effect offolic acid supplementation on serum lipids composition in a rat model of cholestasis. 81 maleWistar rats were randomly divided into nine experimental groups with 9 rats in eachgroup.Group 1, normal control rats ,Group 2, sham-operated rats (The rats in this groupunderwent the same procedure except that the bile duct ligation) ,Group 3, cholestatic rats,Groups 4-6, folic acid control rats;Groups 7-9, cholestatic rats treated with folic acid; Folic acidtreated groups were given folic acid (1,5,10 mg/kg) respectively , once a day by gavage for 28days. Cholestasis was produced by Bile Duct Ligation (BDL). Serum samples were analyzedbiochemically and lipids profile were measured according to standard protocols. cholestatic ratsgroup showed higher concentrations of total cholesterol (TC) , triglyceride (TG) and low densitylipoprotein cholesterol (LDL) in serum. Administration of folic acid supplementation ,significantly decreased the serum levels of TC , TG, and LDL and increased the serum level ofhigh-density lipoprotein cholesterol (HDL). Cholestasis induced hypercholesterolemia and Folicacid supplementation showed hypolipidemic and hypocholesterolemic effects in cholestatic rats.These effects on the lipid profile varied with the different concentrations of folic acid. Ourresult suggested that Folic acid can be used an antilipidemic agent in pation with cholestasis. Manuscript profile -
Open Access Article
4 - Effects of thymol on atheroma plaque, concentration of blood lipids and atherogenic indices serum in male NMRI mice fed with a high-cholesterol diet
Karkhaneh, L., Yaghmaei, P.*, Ebrahim-Habibi, A., Parivar, K., Sadeghizadeh, M. .Atherosclerosis is characterized by the accumulation of fat and inflammatory response in the artery intima and can cause narrowing or complete blockage of the artery. Thymol is a phenolic monoterpene with antioxidant and anti-inflammatory properties. The aim of this stu MoreAtherosclerosis is characterized by the accumulation of fat and inflammatory response in the artery intima and can cause narrowing or complete blockage of the artery. Thymol is a phenolic monoterpene with antioxidant and anti-inflammatory properties. The aim of this study was to evaluate the effects of thymol on blood lipids, atherogenic indices and atheroma plaque of NMRI mice fed a high-cholesterol diet (HCD). 45 NMRI male mice were divided into 5 groups (n=9): Animals of the control group received a normal diet. Whiles in the HCD group received a diet containing 2% cholesterol for 18 weeks. Animals of the sham group received HCD for 12 weeks and then normal diet for 6 weeks with a thymol solvent (oil). The experimental groups 1 and 2 received HCD for 12 weeks and then received a normal diet with thymol at doses of 12 mg/kg and 24 mg/kg for 6 weeks, respectively. At the end of study, concentration of serum lipids and atherogenic indices were measured. Also aorta was measured microscopically. In the present study, consumption of HCD resulted in the formation of atheroma plaque, increased serum triglycerides, total cholesterol concentration, atherogenic indices and significantly decreased high density lipoprotein cholesterol (HDL-C). Treatment with both doses of thymol significantly reduced these changes and improves blood lipids, atherogenic indices was normal and atheroma plaques. The results of this study suggest that thymol can be used for treatment of increased total cholesterol and triglycerides and to improve the atheroma plaque. Manuscript profile -
Open Access Article
5 - Effect of hydro-alcoholic extract of Pistacia Vera L. on the severity of hypercholesterolemia lesions in rabbit aorta
Rahmanian, E., Naeimi, S.*, Rassoli, B., Tahmasebi, F. .Atherosclerosis is the leading cause of cardiovascular diseases. The aim of this study is evaluating the effect of Pistacia Vera L. extract of Pistacia Vera L. on the severity of hypercholesterolemia lesions in rabbit aorta. For this purpose, 25 adult female rabbits pas MoreAtherosclerosis is the leading cause of cardiovascular diseases. The aim of this study is evaluating the effect of Pistacia Vera L. extract of Pistacia Vera L. on the severity of hypercholesterolemia lesions in rabbit aorta. For this purpose, 25 adult female rabbits passed adaptation period and they have been divided in to 5 treatment groups of 5 rabbits each, included: scheme, positive control 1, positive control 2, treatment and negative control. Scheme group was fed with normal diet. Positive control 1 and 2 were fed by corn oil and cholesterol as the same amount of treatment respectively. Treatment was fed with Pistachios extract with the amount of 1,000 mg/kg. Furthermore, corn oil with the amount of 1 ml/kg with adding 1 percent cholesterol of total consuming food weight were administrated to treatment by gavage. Negative control was prescribed with 1000 mg/kg oral administration of Pistachios. In this study, no change in aortic tissue was observed in the scheme group. In the positive control 1 (receiving corn oil), there was no precipitation. The treatment compared with negative control (receiving cholesterol) indicated less amount of fatty deposits in aortic tissue. In the negative control (receiving pistachio extract) there was also no precipitation. This study indicates that pistachio extract can help in reduction of atherosclerosis side effects and reducing fat deposits in aortic tissue layer intima and media in hypercholesterolemic rabbits. Manuscript profile -
Open Access Article
6 - Effect of hydro-alcoholic extract of Pistacia Vera L. on the severity of hypercholesterolemia lesions in rabbit aorta
Rahmanian, E., Naeimi, S., Rassoli, B., Tahmasebi, F. .Atherosclerosis is the leading cause of cardiovascular diseases. The aim of this study is evaluating the effect of Pistacia Vera L. extract of Pistacia Vera L. on the severity of hypercholesterolemia lesions in rabbit aorta. For this purpose, 25 adult female rabbits pas MoreAtherosclerosis is the leading cause of cardiovascular diseases. The aim of this study is evaluating the effect of Pistacia Vera L. extract of Pistacia Vera L. on the severity of hypercholesterolemia lesions in rabbit aorta. For this purpose, 25 adult female rabbits passed adaptation period and they have been divided in to 5 treatment groups of 5 rabbits each, included: scheme, positive control 1, positive control 2, treatment and negative control. Scheme group was fed with normal diet. Positive control 1 and 2 were fed by corn oil and cholesterol as the same amount of treatment respectively. Treatment was fed with Pistachios extract with the amount of 1000 mg/kg. Furthermore, corn oil with the amount of 1 ml/kg with adding 1 percent cholesterol of total consuming food weight were administrated to treatment by gavage. Negative control was prescribed with 1000 mg/kg oral administration of Pistachios. In this study, no change in aortic tissue was observed in the scheme group. In the positive control 1 (receiving corn oil), there was no precipitation. The treatment compared with negative control (receiving cholesterol) indicated less amount of fatty deposits in aortic tissue. In the negative control (receiving pistachio extract) There was also no precipitation. This study indicates that pistachio extract can help in reduction of atherosclerosis side effects and reducing fat deposits in aortic tissue layer intima and media in hypercholesterolemic rabbits. Manuscript profile -
Open Access Article
7 - Isolation and Identification of Lactobacillus Acidophilus Probiotic Bacteria from Traditional Tarkhineh Food and Their Ability to Lower Cholesterol and Triglyceride Levels in vitro
P. Afshar K. Amini H. Mohajerani S. Saki Introduction: Isolation and identification of probiotic strains from native foods can lead to finding strains with unique capabilities. The aim of this study was to isolate, identify and evaluate the ability of Lactobacillus acidophilus bacteria isolated from trad More Introduction: Isolation and identification of probiotic strains from native foods can lead to finding strains with unique capabilities. The aim of this study was to isolate, identify and evaluate the ability of Lactobacillus acidophilus bacteria isolated from traditional Tarkhineh food in lowering cholesterol and triglyceride levels in vitro.Materials and Methods: Native strains of Lactobacillus acidophilus were isolated from a local food called Tarkhineh using culture medium and identified based on phenotypic characteristics, standard biochemical tests and 16SrRNA sequencing. In the next step, the strains were examined for probiotic properties such as resistance to acid and bile and sensitivity to antibiotics. Cholesterol and triglyceride lowering activity of isolates in culture medium was also investigated by o-phthaldehyde method.Results: The results showed that 16 strains of Lactobacillus acidophilus were isolated from Tarkhineh samples, among which four strains (S3, S12, S6, S5) showed 30 to 50% resistance, three strains (S7, S4, S10). had 50 to 75% resistance and 2 strains (S11, S1) had 75 to 100% growth in acidic MRS. In addition, strains S7 and S1 showed a growth rate of 0.3 to 0.5% and strains S4, S3, S11 grew at 0.7% bile salt in MRS medium. The highest cholesterol uptake was observed in S11 and S1 strains at 64± 0.23 and 60±0.18 (p<0.01) respectively. Strains S1 and S11 applied 72% ± 0.64 and 61 ± 0.25% triglyceride reduction respectively.Conclusion: The data of this study showed that the native strains of Lactobacillus acidophilus isolated from the local food of Tarkhineh had the potential to absorb and reduce cholesterol and triglycerides of the culture medium. These strains can be studied in laboratory animals as probiotics capable of absorbing and removing fat. Manuscript profile -
Open Access Article
8 - The Effect of Butter Making Procedure on the Nutritional Characteristics and Cardiovascular Risk Factors
L. Roufehgari Nejad M.R. Ehsani M. Mizani M. Tabibi Azar Introduction: In the Northwest part of Iran, a traditional product with high popularity among consumers is produced and is named “Nehre Butter”. This study is concerned to evaluate and compare the nutritional characteristics of this product with the i More Introduction: In the Northwest part of Iran, a traditional product with high popularity among consumers is produced and is named “Nehre Butter”. This study is concerned to evaluate and compare the nutritional characteristics of this product with the industrial products, with a particular emphasis on the risk factors for cardiovascular disease. Materials and Methods: Industrial and traditional butter samples were prepared and fatty acid profile and cholesterol content were measured using gas chromatography and atherogenic and thrombogenic indexes were calculated. In order to investigate the effect of feeding prepared butters, 40 Wistar rats were randomly divided into four groups of ten, including one control group and three groups were treated with fermented cream butter, non-fermented cream butter and traditional butter respectively. The end of the sixty days treatment period, serum cholesterol, triglycerides, LDL-C and HDL-C were measured using colorimetric methods. Results: The most favourable thrombogenic and atherogenic indexes, hypercholesterolemic/ hypocholesterolemic ratio and cholesterol content were found in the traditional butter. The traditional butter also showed a high percentage of conjugated linoleic acid. In the case of the biological model survey, serum lipids were higher in the traditional butter fed rats as compared to the control, but lower than cream butter fed groups. Conclusion: This study showed that the traditional butter due to its mild effects on health in comparison with the industrial ones is recommended, although moderate consumption is advised. Manuscript profile -
Open Access Article
9 - Evaluation of α-Tocopherol and β-Sitosterol in Distillates of Refined Olive Oil
F. Kalateh Seifari M. Ghavami B. Ghiassi TarziIntroduction: Olive oil, as the major source of lipids in the diet, has a high amount of unsaturated fatty acids and biological components such as phenolic antioxidants that could prevent the destructive effect of free radicals and mutation of cell structures. The nonsa MoreIntroduction: Olive oil, as the major source of lipids in the diet, has a high amount of unsaturated fatty acids and biological components such as phenolic antioxidants that could prevent the destructive effect of free radicals and mutation of cell structures. The nonsaponifiable components of vegetable oils are good sources of specific compounds such as sterols, tocopherols, squalene, fatty acids, and other substances. The aim of this investigation is to determine the components in particular α-Tocopherol and β-Sitosterol through deodorization process and have been accumulated in the distillate tank.Materials and Methods: Olive oil and distillates were provided by Roghan-e-Ziton Nabe Tavakoly manufacturing company. Sterols ad tocopherols were evaluated before and after the deodorization process and in the distilled tank. Qualitative and quantitative determination of sterols and tocopherols were conducted using gas chromatography and high-performance liquid chromatography after the extraction of nonsaponifiable matters.Results: The results showed that the deodorization process decreased the nonsaponifiable matters of olive oil such as sterols, tocopherols, hydrocarbons and some other components namely free fatty acids. Due to the lower temperature of the deodorization process for olive oil, in comparison to soyabean or sunflower oils, the accumulation of these components in the distilled tank were lower. There was no significant difference between sterol composition in distilled tank and oil samples.Conclusion: Collected compounds in the distilled tank are valuable sources of vegetable sterols and α-tocopherol which might be employed in food and pharmaceutical formulation and industries. Manuscript profile -
Open Access Article
10 - Effect of Deep Frying on Fatty Aid Composition and Sterol Content of Grape Seed Oil
S. Gholam Saghaee Z. Piravi VanakIntroduction: Grape seed oil is important to human health due to its very pleasant taste, odor, as well as its high nutritional values. Consumption of the grape seed oil in the diet has been increasing in recent years. Long periods of heating will deteriorate the oil an MoreIntroduction: Grape seed oil is important to human health due to its very pleasant taste, odor, as well as its high nutritional values. Consumption of the grape seed oil in the diet has been increasing in recent years. Long periods of heating will deteriorate the oil and fried products due to oxidative and hydrolytic changes and reactions. Therefore, accurate control of the frying processes and changes are quiet essential. Materials and Methods: In this study, the effects of deep frying at 180 °C (24 and 48 hours) on some chemical characteristics of grape seed oil namely sterol profile and fatty acid composition have been studied using chromatography techniques. Results: The results indicated that, the predominant fatty acid was linoleic acid, and by increasing the heating period, more unsaturated fatty acids namely linoleic acid was decreased due to oxidation. The phytosterols study showed that beta-sitosterol was the predominant phytosterol and deep fat frying did not affect its concentration. Conclusion: Due to the high concentration of linoleic acid and beta-sitosterol in grape seed oil, it might be stated that the oil has a high nutritional value, but considering the changes during frying it might not be recommended for frying practices. Manuscript profile -
Open Access Article
11 - Evaluation of the Effect of Refining Operations on Olive Oil Sterols in Iranian Oil Industry
M. Azadeh Ranjbar A. GhavamiIntroduction: Olive oil due to the unique characteristics being monounsaturated, resistant to oxidation, having considerable quantities of phenolic compounds namely α-tocopherol, being liquid at room temperature with excellent taste and aroma might be regarded as MoreIntroduction: Olive oil due to the unique characteristics being monounsaturated, resistant to oxidation, having considerable quantities of phenolic compounds namely α-tocopherol, being liquid at room temperature with excellent taste and aroma might be regarded as a healthy oil. The aim of this study is to investigate the effect of refining operation on the sterol content of olive oil in Iran's oil industry. Materials and Methods: Samples were prepared before and after refining from three brands of olive oil production industries. Each sample was subjected to determination of iodine, saponification values and isolation of non saponifiable mater. The samples were also subjected to fatty acid and sterol analyses and compositions according to the standard methods defined nationally. Results: The results of this study indicated that small changes in fatty acid composition and values related to fatty acids have occurred. The study also indicated that the sterols have been affected by refining operations and has been lost and collected mainly in the distillate. Conclusion: The results of this study confirms that olive oil refining affects the quantities of sterols and these compounds with others namely tocopherols are collected in the distillate. Therefore distillate collected after deodorization of olive oil might be considered as a valuable fraction to be used in industries. Manuscript profile -
Open Access Article
12 - Fatty Acid and Sterol Composition of Oils Extracted from Pistachio, Walnut, Hazelnut and Almond Employing by Cold Press Method
Z. Piravivanak Sh. PoufalatoonIntroduction: Oils extracted from nuts by the cold press might be regarded as valuable oils due to their high yield, unique flavors characteristics. Due to the role of nuts in Iranian society regarding its high consumption, this preliminary study concerned with the fatt MoreIntroduction: Oils extracted from nuts by the cold press might be regarded as valuable oils due to their high yield, unique flavors characteristics. Due to the role of nuts in Iranian society regarding its high consumption, this preliminary study concerned with the fatty acid and sterol compositions of the oils extracted from the related nuts by cold press have been carried out. Materials and Methods: To define the chemical compositions of nut oils, four nuts consisting of pistachio, walnut, hazelnut and almond were collected from Kerman, Tuyserkan, Qazvin and Azarshahr areas respectively and the oils were extracted at 25°C using the cold press methods. Fatty acid and sterol compositions were determined using a gas chromatography equipped with a capillary column and Flame Ionisation Detector according to the defined methods of standard. Results: The results showed that oleic acid was predominant fatty acid in hazelnut (83.3%), almond (67.6%) and pistachio (63.3%) oils while the linoleic acid had the highest concentration in walnut oil (52.5%). The analysis of the sterol fractions of the nonsaponifiable matters of the extracted oils indicated that the apparent β-sitosterol was the predominant sterol and covered 85-91% of the total sterol fractions in all the oils examined. Conclusion: The results showed that the oils extracted from nuts have desirable quantities of oleic and linoleic acids. The results also indicated the absence of trans acids. Due to the presence of high concentrations of oleic acid in hazelnut, almond and pistachio, these oils have a good stability against oxidation chain reactions. Manuscript profile -
Open Access Article
13 - Physicochemical Evaluation of Purslane Seed Oil
Neda Ahmadi Kamazani Maryam AmiriIntroduction: purslane (Portulaca oleracea) is a member of the portulacaceae .Purslane has been described as a power food of the future because of its high nutritive and antioxidant properties. Purslane is listed in the world health organization as one of the most used MoreIntroduction: purslane (Portulaca oleracea) is a member of the portulacaceae .Purslane has been described as a power food of the future because of its high nutritive and antioxidant properties. Purslane is listed in the world health organization as one of the most used medicinal plants and it has been given the term “ Global panacea “. This study is concerned with the evaluation of physicochemical characteristics of the oil extracted from purslane seeds.Materials and Methods: In this research work purslane seeds were subjected to oil extraction. The extracted oils were subjected to a series of physical and chemical tests consisting of fatty acid composition, iodine value, colour measurement, saponification value, nonsaponifiable matter contents, acid value, peroxide value, phospholipids contents, metal contents, sterols and tocopherol compositions and contents.Results: The extracted oils accounted for 13.4% of the total weight of the seeds. The fatty acid profile of the isolated oil indicated that linoleic and V– linolenic acids were the predominant fatty acids present. Examination of the isolated nonsaponifiable matter of the oil showed that V- tocopherol and X- sitosterol were the predominant tocopherol and sterol respectively.Conclusion: It was concluded that purslane seeds oil due to its high nutritive and antioxidant values might be regarded as a valuable oil for human consumption. Manuscript profile -
Open Access Article
14 - Evaluation of Physicochemical and Microbial Properties of Low-Fat Mayonnaise Formulated with a Type of Potato Starch as a Substitute of Egg Yolk
Sh. Ghazaei M. Mizani z. Piravi vanak M. AlimiIntroduction: The consumption of mayonnaise has been increasing worldwide and egg yolk is a key ingredient in mayonnaise which along with its positive functional properties may cause some problems due to its high cholesterol content (186-213 mg). Additionally it might l MoreIntroduction: The consumption of mayonnaise has been increasing worldwide and egg yolk is a key ingredient in mayonnaise which along with its positive functional properties may cause some problems due to its high cholesterol content (186-213 mg). Additionally it might lead to the allergic reactions in consumers and induce microbial contamination in the final product. The main object of this research is to replace egg yolk partially with a type of modified potato starch (Octenyl Succinic Anhydride, OSA) and determine its best quality and concentration in reduced-fat mayonnaise formulation from the physico-chemical and microbial aspects. Materials and Methods: Mayonnaise samples were prepared by replacing 0, 25, 50, 75 and 100% of the weight of egg yolk with OSA starch. Chemical (acidity, pH, fat content), physical (emulsion stability, color) and microbial (total microbial count, mold, yeast, Lactobacillus, E.coli, Staphylococcus aureos and Salmonella) tests have been carried out on all of the samples and the selected sample was analysed for cholesterol content. Results: The results indicated that by reducing the amount of egg yolk, the pH, fat content, yellowness and microbial contamination of the samples were reduced and those with 25 and 50% substituted- egg yolk, showed the lowest emulsion stability and therefore were eliminated from the rest of the research and cholesterol contents of the other samples were determined. Conclusion: According to the results, 84.9% and 1.78% reductions in cholesterol and fat contents were obtained, respectively, by replacing 75% of egg yolk with OSA as compared to the control. Therefore the mentioned sample has been chosen as the best formulation for low fat/low cholesterol mayonnaise. Manuscript profile -
Open Access Article
15 - An Overview of Kermanshahi Oil as a Functional Food
B. Mehraban Kh. Safaei M. Chalabi -
Open Access Article
16 - Detection of Chemical Properties of Ghee Containing Various Levels of Palm Oil and Beef Tallow on RSM
S. H. Erfani M. Ghavami S. Shoeibi H. Rastegar A. Zand Moghaddam -
Open Access Article
17 - The Effects of Refining Operations on Quality and Quantity of Sterols in Canola, Soyabean and Sunflower Seed Oils
M. Azizi A. Ghavami -
Open Access Article
18 - Evaluation and Analysis of the Ultrasound-Assisted Extracted Tomato Seed Oil
N. Ahmadi Kamazani H. Tavakolipour M. Hasani M. Amiri -
Open Access Article
19 - Evaluation of Chemical Characteristics of Extra Virgin Olive Oils Extracted from Three Monovarieties of Mari, Arbequina and Koroneiki in Fadak and Gilvan Regions
M. Homapour M. Ghavami Z. Piravivanak E.S. Hosseini -
Open Access Article
20 - Qualitative and Quantitative Evaluation of Tocopherols and Phytosterols in Soybean Oil Distillate
H. Alighaleh babakhani M. Ghavami M. Gharachorloo -
Open Access Article
21 - Different methods using GnRHa on out of season reproductive efficiency in male goldfish (Carassius auratus, Linnaeus 1758)
احسان احمدی فر محمدرضا ایمانپور کوروش امینی وحید زادمجید طیبه عنایت غلامپورThe present research aims to evaluate effects of different methods of LHRHa implants and injections on some biological properties of semen including sperm density, spermatocrit percentage, pH and duration of sperm motility during spermiogenesis, sperm volume during 21 d MoreThe present research aims to evaluate effects of different methods of LHRHa implants and injections on some biological properties of semen including sperm density, spermatocrit percentage, pH and duration of sperm motility during spermiogenesis, sperm volume during 21 days after treatment and testosterone hormone changes in the days after implant and injection (Spermiogenesis, 7, 14 and 21) after the treatment in male goldfish broodstock in non-reproduction season. Fish were included in 4 treatments (injection of normal saline 0.7%, EVAc 20 mg / kg body weight LHRHa with 40 micrograms / kg body weight Metoclopramide, cholesterol pellets containing 20 micrograms / kg body weight LHRHa with 40 mg / kg body weight Metoclopramide and 100 mg / kg LHRH with 40 mg / kg body weight Metoclopramide. sperm did not differ significantly between treatments (P ≥0.05). highest spermatocrit percentage was found in treatments EVAc and LHRHa (P ≥0.05). EVAc implants significantly increased sperm volume compared with other treatments during the 21 days after treatment (P ≥0.05). Mobility period in different treatments of male fish broodstock was differed significantly (P ≥0.05), so that mobility period in treatment EVAc mobility was higher than other treatments. PH of different treatments with the control group (Physiology serum injection) showed significant difference so that the lowest rate was observed in the control group (P ≥0.05). Changes in hormone testosterone showed that its rate in Spermiogenesis in EVAc and LHRHa injection treatments showed significant difference compared to other treats in off-season reproduction of goldfish Manuscript profile -
Open Access Article
22 - Association of Limbs Lenghts and Circumferences, Waist to Hip Ratio, BMI and other Body Dimensions with Lipid Profile and Blood Glucose
Mohsen Jafari alireza abdollahi nahid bizhehBackground: Health professionals are seeking simple methods for evaluation of atherosclerosis risk. The aim of this study was determination of relationship between body dimensions with atherosclerosis risk factors. Methods: Subjects of this study were inactive middle-ag MoreBackground: Health professionals are seeking simple methods for evaluation of atherosclerosis risk. The aim of this study was determination of relationship between body dimensions with atherosclerosis risk factors. Methods: Subjects of this study were inactive middle-aged men (n=102) and women (n=77). Anthropometric indices (size, breath and circumferences of body segments), lipid profile (blood cholesterol, triglyceride, highdensity lipoprotein and low density lopoprotein) and blood glucose of the subjects were determined using standard methods. Results: Waist circumference, hip circumference, waist to hip ratio (WHR), waist to thigh ratio (WTR), waist to height ratio (WHtR), trunk size, second to fourth digit ratio, suprailiacus skinfold fat and subscapularis to triceps skinfold ratio (STR) in men and body mass index (BMI), waist circumference, hip circumference, trunk size, second and fourth digit lengths, triceps and suprailiacus skinfold fat and WHtR in women were significantly related to the risk of dyslipidemia (P≤0.05). Conclusion: Hip circumference, suprailiacus skinfold fat and WHtR in both sexes have positive relationship with the risk of atherosclerosis. Waist circumference, WTR and WHR in men and BMI in women have stronger correlation with atherosclerosis. Manuscript profile -
Open Access Article
23 - Effect of phytosterol and Bacillus coagulant probiotic in reducing blood cholesterol
Maryam Arjomandi far Bahareh Pakpour Rahebeh Amiri DehkharghaniTarget and background: In recent years, many studies have been conducted on high-risk factors for some blood lipids, which can lead to the development of cardiovascular diseases. The most important goal of this study is to investigate the effect of phytosterol and Bacil MoreTarget and background: In recent years, many studies have been conducted on high-risk factors for some blood lipids, which can lead to the development of cardiovascular diseases. The most important goal of this study is to investigate the effect of phytosterol and Bacillus coagulant probiotic on the reduction of blood cholesterol in adult rats. Material and Methods: 40 Male NMRI mice with a weight of 25-30g were used .The mouse were divided into 5 groups of 8, including: control group, HCD group (1% of the weight of the food consumed cholesterol diet), Experimental group 1 (daily, in addition to cholesterol diet, 0.1g of phytosterol Experimental group 2 (daily, in addition to cholesterol diet, 0.2g of Bacillus coagulant bacteria plus animal oil was gavaged), Experimental group 3 (daily, in addition to cholesterol diet, 0.1g combination of phytosterol and Bacillus coagulants probiotic were digested with germicidal oil). Sperry samples were taken from the blood samples at the end of the experiments, and cholesterol, triglycerides, HDL and LDL blood samples were measured and. Results: Cholesterol, triglyceride, HDL and LDL showed a significant decrease compared to the control group. Conclusion: According to the above results, it can be said that phytosterol and Bacillus coagulant probiotic simultaneously decrease blood lipids, and therefore, it is recommended to use this pump. Manuscript profile -
Open Access Article
24 - Antibacterial activity of Butia odorata extracts against pathogenic bacteria
Darla Maia Bianca Aranha Fabio Chaves Wladimir Silva -
Open Access Article
25 - Evaluation of cholesterol lowering property of selected herbs in ghee (heat clarified milk fat)
Krupaben M. Shingala Rayan V. Lunagariya Bhavbhuti M. Mehta V.B. Darji K.D. Aparnathi -
Open Access Article
26 - Effect of β-sitosterol-enriched walnut oil on blood parameters and liver function in diabetic rats
Monireh Ghorbani عبدالحسین شیروی Gholamhassan Vaezi Vida Hojati Hamid SepehriProblems and complications associated with liver enzyme changes can be regarded as some effects of Diabetes Mellitus. Using a nutritional approach is a significant part of the prevention, control and treatment process. The aim of this study was to investigate the effect MoreProblems and complications associated with liver enzyme changes can be regarded as some effects of Diabetes Mellitus. Using a nutritional approach is a significant part of the prevention, control and treatment process. The aim of this study was to investigate the effect of walnut oil enriched with beta-cytosol on blood parameters of liver function in diabetic rats.The study sample consisted of 30 mice divided into 5 groups of 6 rats, where each group was kept in a separate cage. Five treatments were considered in this experiment, where control group received normal saline, the second treatment were given pure walnut oil without the addition of β-sitosterol and the other three groups were gavaged with 30, 45, 60 mg / kg β-sitosterol. After 4 weeks of gavage, the next stage of blood sampling was performed. Insulin and blood glucose were measured after blood serum separation along with the measurement of blood factors such as cholesterol, triglyceride, high-density cholesterol (HDL), aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP), total bilirubin, direct bilirubin, and albumin. Significant differences existed among the mean values of the tests in the control group and the intervention groups without, with 30 mg/kg, with 45 mg/kg, and with 60 mg/kg β-sitosterol. These significant differences among the treatments were seen in mean fasting blood sugar, cholesterol, triglyceride, high-density cholesterol (HDL), total aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP), total bilirubin, direct bilirubin, and albumin.β-sitosterol-enriched walnut oil can be regarded as a helpful option to control diabetes. Manuscript profile -
Open Access Article
27 - Application of minor compounds in detection of vegetable oils adulteration (Review Article)
F. Hashempour-Baltork M.A. Torbati S. Azadmard-DamirchiOils and fats have important roles in cooking, frying and salad dressings or in food formulations. Adulterants misusing from the oil market in different ways including blending expensive oils with cheaper ones or incorrect labeling to inform variety, geographical origin MoreOils and fats have important roles in cooking, frying and salad dressings or in food formulations. Adulterants misusing from the oil market in different ways including blending expensive oils with cheaper ones or incorrect labeling to inform variety, geographical origin and production process method. In recent years, researchers have suggested several methods for analyzing oils and determination of their minor and major compounds based on the high-performance liquid chromatography (HPLC) and gas chromatography (GC) methods. The oils have a different composition of sterols, tocopherols, hydrocarbons, pigments, lignans and phenolic compounds which can be detected by HPLC and GC methods. The aim of this study was to evaluate and review the application of vegetable oil minor compounds including sterols, tocopherols, hydrocarbons, pigments, lignans, phenolic compounds and volatile compounds to detect of their adulteration. Manuscript profile -
Open Access Article
28 - Detection and quantification of phytosterols in yogurt using gas chromatography
M. Jeddy J. KhandaghiSterols form the largest proportion of the unsaponifiable fraction of lipids. Plant fats and oils contain phytosterol as naturally occurring constituents. The most common types of phytosterols in plants are cytosterol, compressor and stigmometol. Different types of yogu MoreSterols form the largest proportion of the unsaponifiable fraction of lipids. Plant fats and oils contain phytosterol as naturally occurring constituents. The most common types of phytosterols in plants are cytosterol, compressor and stigmometol. Different types of yogurt and especially high-fat types are foods that are likely to contain added phytosterol. In this study, the presence of cholesterol and four phytosterols in 62 different yogurts in Tabriz city was investigated in order to assess the addition of vegetable oils. For this purpose, after saponification and liquid-liquid extraction of the samples, non-absorbent materials were purified by thin layer chromatography. Then, without the derivative step, the compounds were detected by gas chromatography with a flame ionization detector. In the recent study, the saponification process was optimized and validated. According to the results, the method was estimated as easy, fast and repeatable, and had a high efficiency in detecting sterols in our samples. Cholesterol was found as the highest sterolic compound in all samples (65-99%). Among the phytosterols, campesterol was predominated (4.7%) followed by brassicasterol (2.08%). According to the guidelines of Institute of Standards and Industrial Research of Iran, 46 (74.2%) yogurt samples were found unacceptable. Manuscript profile -
Open Access Article
29 - The effect of hydroalcoholic extract of Scrophularia striata on the changes of testis tissue in hypercholesterolemic rats
Ayub Mahdavi Ali Mohammad Bahrami Shahnaz YousefizadehHypercholesterolemia can caused infertility with producing side effects such as the production of free radicals.One of these useful herbal remedies Scrophularia striata which native name is Tashnehdari.This study aimed to investigate the effect of Scrophularia striata e MoreHypercholesterolemia can caused infertility with producing side effects such as the production of free radicals.One of these useful herbal remedies Scrophularia striata which native name is Tashnehdari.This study aimed to investigate the effect of Scrophularia striata extracts on histomorphometric changes of testicular tissue in rats fed a high-calorie diet. In this experimental study, 32 male rats were assigned into 4 groups including control, diet induced hypercholesterolemia (DIH), DIH+S. striata (400 mg/kg) and S.striata group: The animals in this group first received a normal diet for 4 weeks and then were fed with the extract of Scrophularia striata (400 mg /kg) for 4 weeks by the above method. At the end of the period, the rats were first anesthetized with a ketamine-xylazine combination, and after taking blood from the heart to measure blood cholesterol levels, it was euthanized and the right testicles of all animals were isolated and transferred to a tissue laboratory for tissue smear preparation and histomorphometric study. Data were analyzed by SPSS16. The results showed that after consuming a high-calorie diet in the DIH group, body weight, testicular weight, and blood cholesterol level increased significantly compared to the control group (p < 0.05). Also consuming a high-fat diet reduces the number of spermatogonia, primary spermatocytes, and spermatozoid in the DIH groups. After consuming Scrophularia striata, a relative increase in the number of the above cells was observed in the DIH + Scrophularia striata group (p < 0.05). Therefore, oral consumption of Scrophularia striata following a high-calorie diet can have a protective effects Manuscript profile -
Open Access Article
30 - Effect of vitamin E supplementation on serumic levels of lipids and lipoproteins in cholesterol-fed male rat
M.H Khayat Nouri محمد Mashayekhi رضا Jafari M.R Nasirzade جعفر Rahmani Hypercholesterolemia is one of the risk factors of cardiovascular diseases. High blood cholesterol affects the general health and increases the mortality rate of cardiovascular diseases. High levels of cholesterol in the diet increases LDL levels and More Hypercholesterolemia is one of the risk factors of cardiovascular diseases. High blood cholesterol affects the general health and increases the mortality rate of cardiovascular diseases. High levels of cholesterol in the diet increases LDL levels and decreases the activity of LDL receptors in the liver. Oxidation of vascular LDL lipoproteins increases the development of atherosclerosis. Previous studies have indicated that consumption of antioxidants decreases hypercholesterolemia. This study evaluates the effect of vitamin E supplementation on blood lipid levels in high cholesterol-fed rats. In this experimental study, three groups of male rats (n=10 for each group) were used. The control group received basic diet and one of the other two groups received a diet containing one percent cholesterol and while the other received the same diet plus vitamin E supplement (2500 IU/kg in dry matter of the diet) for one month. After determining the values of TC, LDL, VLDL, HDL and TG the results indicated that in rats fed with 1% cholesterol apart from HDL and VLDL the other lipids had increased significantly compared with the control group (p<0.01). Supplementation with vitamin E significantly decreased the TC and LDL levels in comparison with the 1% cholesterol fed group (p<0.01). This effect of vitamin E may be related to its antioxidant and inhibitory effects on lipoprotein synthesis pathway. The validity of these points in humans needs further investigations. Manuscript profile -
Open Access Article
31 - The effect of the additive containing Artichoke extract (APC) on growth performance, blood cholesterol level, carcass characteristics and immune system of broiler chickens
farang Rouzmehr ardeshir mohit mahmoud KoshSekeh mohammad hassanzade In order to investigate the effect of different levels of the additive containing Artichoke premix concentrated (APC) on growth performance, serum cholesterol level, carcass characteristics and immune responses of broilers two separate trials were conducted More In order to investigate the effect of different levels of the additive containing Artichoke premix concentrated (APC) on growth performance, serum cholesterol level, carcass characteristics and immune responses of broilers two separate trials were conducted. In the first trial, APC was added at three levels of 0, 100 and 200 gr/ton diet during the first 21 days of growing period. One hundred and fifty unsexed day old broiler chickens of Ross strain were randomly divided in three groups with 5 replicate of 10 chicks in each cage, by a completely randomized design. At the end of each week, the birds were weighed individually and feed conversion ratios calculated. In order to determine serum cholesterol level, at day 21 blood sample was taken from 15 chickens per treatment. At the end of the 42nd day, 5 birds from each group were randomly selected and slaughtered for investigation of carcass characteristics. In the second trial, the effects of APC at 150gr/ton feed were studied on growth parameters and immune function of broiler chickens in a commercial farm. The results showed that application of APC in a level of 200 gr/ton diet significantly increased body weight of chickens at the first (p<0.01) and sixth weeks (p<0.05) of age. Feed conversion ratio was improved significantly during the 0-7 (p<0.01), 0-21 (p<0.05) and 0-42 (p<0.01) days. The blood cholesterol level significantly (p<0.01) decreased in group of chickens that were fed APC in the diet when compared with the control birds. The carcass characteristics showed a significant increase (p<0.01) in average live weight, carcass weight, thigh and breast weights of Arc fed birds compared with the control birds, as treatment with APC significantly decreased abdominal fat of treated birds (p<0.05). On the other hand in the commercial farm conditions, APC cause improved growth performance and immune responses of broiler chickens but such improvements were not significant. Manuscript profile -
Open Access Article
32 - Study on the effect of Lactobacillus casei o1 fermented milk consumption on lipid pattern of rats nourished with cholesterol enriched diet
حمید Mirzaei بهرام Amouoghli Tabrizi مهدی RafieiThe aim of this study was to evaluate the effects ofconsumption of different amounts of fermented milk by L.casei on serum lipid trends including total cholesterol, LDL-C, HLD-C, VLDL-C and triglyceride in the serum of rats fed 1 and 2% cholesterol enriched diet. For th MoreThe aim of this study was to evaluate the effects ofconsumption of different amounts of fermented milk by L.casei on serum lipid trends including total cholesterol, LDL-C, HLD-C, VLDL-C and triglyceride in the serum of rats fed 1 and 2% cholesterol enriched diet. For this purpose 49 male albino wistar rats with a body weight of 200±15 gr were randomly allocated to seven groups each containing 7 rats and adapted to new conditions during a week. Rats in the first group (control group) received commercial diet and water for 30 days, the second to fourth groups received diet enriched with 1% cholesterol and rats in the fifth to seventh groups received diet enriched with 2% cholesterol. Each rat in the fourth and seventh groups (double dose receiving treatment groups) consumed fermented milk containing 4×108 CFU bacteria per day, rats in the third and sixth groups (single dose receiving treatment groups) consumed fermented milk containing 2×108 CFU bacteria per day and in the second and fifth groups (sham group) consumed sterilized milk instead of fermented milk. According to the statistical tests, one way analysis of variance and Tukey at a level of α= 0.05, mean levels of total cholesterol and LDL-C of rats in the double dose receiving treatment groups and single dose receiving treatment groups were significantly lower and mean level of HDL-C was significantly higher than sham group (p<0.05). In the rats fed 1% enriched cholesterol, mean levels of VLDL-C and triglyceride of rats in the double dose receiving treatment groups were significantly lower than sham group (p<0.05). Long term daily consumption of milk fermented by L.casei improves serum lipid trends by lowering total cholesterol and LDL-C level and by increasing HDL-C level. The effectiveness of this probiotic on lipid trends is dose dependent. Manuscript profile -
Open Access Article
33 - Evaluation of the levels of Leptin, Beta hydroxyl butyrate, Glucose, Cholesterol and Triglyceride in serum of Holstein cows with sub clinical ketosis
سیامک Asri Rezayi بهرام Amouoghli Tabrizi بابک Saber MaroufLeptin hormone is secreted from the white adipocytes of adipose tissue and its levels increase with the increase in size of the adipose tissue. One of the most important actions of this hormone is the regulation of body metabolism by consuming adipose tissue and p MoreLeptin hormone is secreted from the white adipocytes of adipose tissue and its levels increase with the increase in size of the adipose tissue. One of the most important actions of this hormone is the regulation of body metabolism by consuming adipose tissue and production of energy. The objective of this study was determination of Leptin and BHB, glucose, cholesterol and triglyceride levels in healthy Holstein cows and cows with Sub clinical Ketosis and the determination of the prevalence of Sub clinical Ketosis, using BHB level in blood serum as the gold standard. In this survey 7 dairy farms were chosen in Shahriar, (Tehran province), Samples were taken from 100 cows at two periods: 1) last week of pregnancy (dry period), 2) The same cows at 2 months after parturition. Serum samples were harvested and leptin levels were measured using DBC ELISA kit,Canada, BHB levels were measured using RANBUT kits and glucose, cholesterol and triglyceride levels were measured by commercial kits (ziest chem) and spectrophotometer. In this study, the prevalence of Sub clinical Ketosis, using the 1/2, 1/4, 1/7 mmol BHB, as the cut point was calculated as 18%, 14% and 4% respectively. Leptin levels decreased significantly after parturition in healthy cows and those affected by subclinical ketosis. There was a significant correlation between leptin and glucose (r=0.53) and BHB and glucose (r= -0.27) in pre parturient group of cows. In the group of cows 2 month after parturition, there was a significant correlation between leptin and glucose (r=0.65), BHB and triglyceride (r=0.97) and BHB and glucose (r= -0.64). In the group affected by subclinical ketosis, a significant correlation was observed between leptin and glucose (r=0.72), BHB and glucose (r=-0.38), BHB and triglyceride (r=0.85) and BHB and cholesterol (r=0.64). Manuscript profile -
Open Access Article
34 - The antioxidant and anti-inflammatory activities of fatty acids and sterols of Eryngium caucasicum Trautv and Caucalis platycarpos L
sahar mohammadipour Abdollah Hatamzadeh Davood Bakhshi Ardalan PasdaranInflammation and oxidative related disorders consist the most important public health threating diseases. This study investigates the fatty acid and sterol contents of E. caucasicum and C. platycarpos, which are part of the nutrition culture of the Caspian region. Their MoreInflammation and oxidative related disorders consist the most important public health threating diseases. This study investigates the fatty acid and sterol contents of E. caucasicum and C. platycarpos, which are part of the nutrition culture of the Caspian region. Their antioxidant and anti-inflammatory potentials are also tested with regard to preparing supplemental foods. The fatty acid and sterol contents are quantified by gas chromatography–mass spectrometry (GC MS), and are identified by comparison to standard components. All fractions were tested for free radical scavenging properties with respect to 1, 1-diphenyl-1-picrylhydrazyl (DPPH), phosphomolybdenum, 2, 2’-azino-bis (3-ethylbenzothiazoline)-6-sulphonic acid radical cation(ABTS), cupric ion reducing activity (CUPRAC), Ferric reducing antioxidant power (FRAP), and metal chelating activity on ferrous ions methods. Furthermore, the anti-inflammatory activity of the fatty acid and sterol fractions of E. caucasicum and C. platycarpos were assayed by the human red blood cell (HRBC) membrane stabilization method. The total oil content of these plants was 18.21% and 7.39%, respectively, with E. caucasicum yielding a higher percentage of oil. Stigmastanol (21.35%) and β-sitosterol (12.19%) constituted the predominant sterols in E. caucasicum and C. platycarpos, respectively. Manuscript profile -
Open Access Article
35 - Isolation and identification of like Bifidobacterium bacteria from traditional Tarkhineh food and evaluation of their ability to lower cholesterol and triglyceride levels in vitro
nasim afshar kumarss amini Hamidreza Mohajerani Sasan sakiIsolation and identification of bacteria with useful properties from local products can play an important role in introducing unique types of probiotics. The aim of this study was to isolate, identify and evaluation of the ability of Bifidobacterium bacteria isolated fr MoreIsolation and identification of bacteria with useful properties from local products can play an important role in introducing unique types of probiotics. The aim of this study was to isolate, identify and evaluation of the ability of Bifidobacterium bacteria isolated from Tarkhineh traditional food in lowering cholesterol and triglyceride levels of the culture medium. Native strains of Bifidobacterium were isolated from a local food called Tarkhineh using general and specific culture media and identified based on phenotypic characteristics, standard biochemical tests and 16S rRNA sequencing. Then, samples with probiotic properties such as resistance to acid and bile were examined in terms of sensitivity to common antibiotics. Cholesterol and triglyceride lowering activity of their culture medium was also measured by o-phthaldehyde method. During this study, 210 bacteria were isolated from Tarkhineh food, including 13 strains of like Bifidobacterium bacteria. Among them, 10 strains were resistant to acid and bile condition. Antibiotic susceptibility analysis showed that most strains were sensitive to common antibiotics and S4 and S1 strains reduced cholesterol in culture medium by 75 ± 0.58 and 71±0.13%, respectively (p<0.01). Among the strains, strains S4, S10 and S1 applied 65%, 63% and 62% reduction of the medium triglyceride, respectively. The data of this study showed that the probiotics isolated from the local food of Tarkhineh had the potential to absorb and reduce cholesterol and triglycerides of the culture medium to a significant extent. It seems that the potential of these strains to improve the lipid pattern can be further investigated. Manuscript profile -
Open Access Article
36 - اثر عصاره ریشه Suregada zanzibariensis (Baill) بر سطح قند خون، پروفایل لیپیدی و بافت شناسی پانکراس در موش های صحرایی دیابتی ناشی از استرپتوزوتوسین-نیکوتینامید
ژاپت جوزفات سیپریان امپیندا راس ماسوBackground & Aim: Ethnobotanical studies have shown that Suregada zanzibariensis roots are used by traditional healers and the community for the treatment of diabetes mellitus. Therefore, this study was undertaken to investigate the effect of the ethyl acetate extra MoreBackground & Aim: Ethnobotanical studies have shown that Suregada zanzibariensis roots are used by traditional healers and the community for the treatment of diabetes mellitus. Therefore, this study was undertaken to investigate the effect of the ethyl acetate extract of Suregada zanzibariensis roots (EAESZ) on blood sugar levels, lipid profile, and pancreatic histology in streptozotocin-nicotinamide-induced diabetic rats.Experimental: Rats were induced to have diabetes by interstitial injection of streptozotocin nicotinamide, followed by daily oral administration of the ethyl acetate extract of Suregada zanzibariensis roots (EAESZ) for 28 days at doses of 350, 500, and 700 mg/kg body weight. The effect of EAESZ on serum lipid profiles and pancreatic β-cells in diabetic rats were examined after 28 days of administration of the extract. While fasting, blood glucose levels were measured every seven days.Results: The administration of EAESZ at doses of 350, 500, and 750 mg/kg significantly decreased the fasting blood glucose levels compared to the diabetic control rats. Also, total cholesterol (TC), low-density lipoprotein (LDL), and triglyceride (TG) levels decreased while high-density lipoprotein (HDL) levels increased in all treated groups compared to diabetic control rats. Furthermore, there was no significant difference (P>0.05) in body weight of treated diabetic rats compared to standard control diabetic rats, while there was a significant difference (P<0.05) with diabetic control rats.Recommended applications/industries: These results indicate that EAESZ has high antidiabetic potential along with significant hypoglycemic and hypolipidemic effects. However, more studies are needed to identify and isolate compounds responsible for those properties. Manuscript profile -
Open Access Article
37 - اثر پلی کوزانول بر کاهش میزان کلسترول، تری گلیسیرید و سایر متابولیت های چربی در خون موش صحرائی
فاطمه فروهی منصور امرایی هادی زمانیمقدمه و هدف: پلی کوزانول ترکیبی از الکل های اصلی با زنجیره بلند است که از نیشکر استخراج می شود. در پژوهش حاضر، تأثیر پلی کوزانول بر کاهش میزان متابولیت های چربی در خون موش های هایپرکلسترولمیک مورد بررسی قرار گرفت.روش تحقیق: 32 سر موش صحرائی نر بالغ نژاد ویستار با میانگی Moreمقدمه و هدف: پلی کوزانول ترکیبی از الکل های اصلی با زنجیره بلند است که از نیشکر استخراج می شود. در پژوهش حاضر، تأثیر پلی کوزانول بر کاهش میزان متابولیت های چربی در خون موش های هایپرکلسترولمیک مورد بررسی قرار گرفت.روش تحقیق: 32 سر موش صحرائی نر بالغ نژاد ویستار با میانگین وزنی 250 گرم که به چهار گروه شامل شاهد (دریافت تنها رژیم غذایی معمولی)؛ کنترل ( رژیم پر کلسترول 2%)؛ گروه تجربی1 و 2 (رژیم پر کلسترول 2% و دریافت پلی کوزانول با دوز 25/0 و 5/0 میلی­گرم در روز) تقسیم شدند. پس از چهار هفته تیمار، و عمل خون­گیری صفات بیوشیمیایی نظیر کلسترول، تری گلیسرید،LDL-C وHDL-C اندازه گیری شدند.نتایج و بحث: نتایج نشان داد که در گروه تجربی1، کاهش معنی داری (p<0.05) در میزان کلسترول و LDL-C و تری گلیسرید و افزایش معنی داری (p<0.05) در میزان HDL-C در مقایسه با گروه کنترل (Sham) به وجود آمد. هم­چنین در گروه تجربی2، کاهش معنی داری (p<0.01) در میزان کلسترول و LDL-C وتری گلیسرید و افزایش معنی داری (p<0.01) در میزان HDL-C در مقایسه با گروه کنترل (Sham) به وجود آمد.توصیه کاربردی/صنعتی: پلی کوزانول احتمالاً می تواند یک ترکیب مؤثر در کاهش میزان کلسترول، LDL-C و تری گلیسرید و افزایش HDL-C باشد. Manuscript profile -
Open Access Article
38 - استفاده سنتی از ( Efó Wòròwó (Solanecio biafrae برای کاهش وزن و چربی
ماتیو اولانیانBackground & Aim: Èfó Wòròwó (Solanecio biafrae) an important vegetable in Nigeria has many health benefits non-scientific claims in herbal practice. This work was designed to evaluate the traditional application of Èf& MoreBackground & Aim: Èfó Wòròwó (Solanecio biafrae) an important vegetable in Nigeria has many health benefits non-scientific claims in herbal practice. This work was designed to evaluate the traditional application of Èfó Wòròwó (Solanecio biafrae) to reduce weight and fats in pre-obesity. Experimental:31 pre-obese individuals (35-70 years; females – 20; Males - 11) with BMI of 27 ± 4.0 kg/m2 who were not on any fat or weight reduction medication and 45 age-matched non-obese volunteers with BMI of 19 ± 2.0 kg/m2 were investigated as control test and control subjects respectively. Plasma cholesterol and triglycerides were measured by spectrophotometry method while BMI was determined by standard method. Results: There was a significantly lower BMI, plasma Total cholesterol and triglycerides in pre-obese subjects after treatment than before treatment (p<0.05). There was a significantly higher total cholesterol, BMI and plasma total triglycerides in pre-obese subjects before treatment than the results obtained in the control subjects (p<0.05). However, there was no significant difference in plasma total cholesterol, BMI and plasma total triglycerides in pre-obese subjects after treatment compared with the results obtained in the control subjects (p>0.05). Recommended applications/industries: This work confirms the traditional health benefit claim of Èfó Wòròwó (Solaneciobiafrae) at reducing plasma total cholesterol, BMI and plasma total triglycerides in pre-obese subjects. Manuscript profile -
Open Access Article
39 - Egg Yolk Cholesterol of Hens Fed Barley Malt Rootlets
S.M. Hashish L.D. Abd El-Samee -
Open Access Article
40 - Cortisol and Postpartum Luteal Function in Cattle
A. Ezzat Ahmed M.N. Ismail M.S. Aref A. Zain El-Abedin A.Y. Kassab -
Open Access Article
41 - اثرات سطوح مختلف کنجاله گوار و آنزیم بتاماناناز بر عملکرد، غلظت کلسترول زرده و فراسنجههای لیپیدی خون مرغهای تخمگذار در مرحله دوم تولید
م. حسنی م. رضایی ز. انصاری پیرسرایی ک. یوسفی کلاریکلائیدر یک آزمایش فاکتوریل 2 × 3 با طرح پایه کاملاً تصادفی، تعداد 72 قطعه مرغ­های تخمگذار تجاری لگهورن سویه­های لاین (W-36) در دوره دوم تخمگذاری (98 هفته) در 24 قفس سیمی (30×30×7/45 سانتی­متر مکعب) به ­صورت تصادفی توزیع و به مدت 12 هفته با Moreدر یک آزمایش فاکتوریل 2 × 3 با طرح پایه کاملاً تصادفی، تعداد 72 قطعه مرغ­های تخمگذار تجاری لگهورن سویه­های لاین (W-36) در دوره دوم تخمگذاری (98 هفته) در 24 قفس سیمی (30×30×7/45 سانتی­متر مکعب) به ­صورت تصادفی توزیع و به مدت 12 هفته با سه سطح کنجاله گوار (0، 4 و 8 درصد) و دو سطح آنزیم همیسل® (0 و 05/0 درصد) تغذیه شدند. هر گروه آزمایشی دارای 4 تکرار و 3 قطعه مرغ در هر تکرار بود. میزان کلسترول تخم­مرغ و غلظت لیپیدهای خون (تری­گلیسرید، کلسترول، لیپوپروتئین با دانسیته کم، لیپوپروتئین با دانسیته زیاد) در 110 هفتگی اندازه­گیری شد. سطوح مختلف کنجاله گوآر اثر معنی­داری بر تولید تخم­مرغ، مصرف خوراک و ضریب تبدیل غذایی نداشت. استفاده از آنزیم در جیره، باعث کاهش معنی­دار مصرف خوراک و بهبود ضریب تبدیل غذایی شد (05/0P<). وزن تخم­مرغ و وزن توده تخم­مرغ به طور معنی­داری تحت تأثیر اثر متقابل کنجاله گوار و آنزیم قرار گرفت (05/0P<). افزودن آنزیم به جیره در سطح 4 درصد کنجاله گوآر وزن و توده تخم­مرغ را کاهش داد ولی در گروه آزمایشی که با جیره شاهد تغذیه شده بودند اثر معکوس داشت. نتایج این آزمایش نشان داد که استفاده از کنجاله گوار تا سطح 8 درصد در جیره مرحله دوم تولید بدون تأثیر منفی بر عملکرد مرغ­های تخمگذار قابل استفاده است. استفاده از کنجاله گوآر سبب کاهش معنی­دار (05/0P<) تری­گلیسیرید خون و تا حدی کلسترول زرده تخم­مرغ شد. مکمل آنزیمی بتاماناناز با کاهش مصرف خوراک سبب بهبود معنی­دار ضریب تبدیل غذایی شد و همچنین اثر معنی­داری بر کاهش کلسترول زرده تخم­مرغ و تری­گلیسیرید سرم داشت (05/0P<). Manuscript profile -
Open Access Article
42 - اثر عصاره آبی الکلی کاسبرگ و برگ چای ترش بر عملکرد، کیفیت تخم مرغ، سامانه ایمنی و تعادل اکسیدانی مرغ های تخمگذار
ش. ثابت سروستانی س.م. حسینی س.ه. فرهنگ فراین آزمایش با هدف بررسی اثر عصاره آبی-الکلی گیاه چای ترش، بر عملکرد، کیفیت تخم­ مرغ، سامانه ایمنی و تعادل اکسیدانی مرغ­ های تخمگذار در طول شرایط محیطی خنثی طراحی شد. 200 قطعه مرغ تخم­گذار سویه های-لاین W-36 (در سن 23 هفتگی) به صورت پنج تیمار آزمایشی با چهار Moreاین آزمایش با هدف بررسی اثر عصاره آبی-الکلی گیاه چای ترش، بر عملکرد، کیفیت تخم­ مرغ، سامانه ایمنی و تعادل اکسیدانی مرغ­ های تخمگذار در طول شرایط محیطی خنثی طراحی شد. 200 قطعه مرغ تخم­گذار سویه های-لاین W-36 (در سن 23 هفتگی) به صورت پنج تیمار آزمایشی با چهار تکرار و 10 پرنده در هر تکرار تقسیم شدند. پرندگان تیمار یک با جیره بر پایه ذرت-سویا بدون عصاره تغذیه شدند، در حالیکه، تیمارهای دو و سه به ترتیب، 300 و 700 میلی­گرم در کیلوگرم عصاره برگ (HSLE) و تیمارهای چهار و پنج به ترتیب، 300 و 700 میلی­گرم در کیلوگرم عصاره کاسبرگ­ (HSLE) چای ترش را دریافت کردند. داده­ های عملکرد شامل تولید تخم ­مرغ، مصرف خوراک، توده تخم­ مرغ تولیدی و ضریب تبدیل خوراک به طور هفتگی ثبت شدند. شاخص­ های کیفیت تخم ­مرغ در هر 28 روز از دوره آزمایش مورد بررسی قرار گرفتند. از هر تکرار دو پرنده انتخاب و برای تعیین سامانه ایمنی و MDA پلاسما خون­گیری شد. همچنین از دو زرده تخم ­مرغ در هر تکرار برای بررسی MDA، کلسترول و تریگلیسرید زرده استفاده شد. مقایسه نتایج نشان داد، HSCE در سطح 700 میلی­گرم بر کیلوگرم نسبت به گروه شاهد میزان تخمگذاری را در زمان اوج تولید (P<0.05) تا 8 درصد افزایش داد. با این حال، تعادل اکسیدانی و عملکرد ایمنی بین گروه­های آزمایشی متفاوت نبود. مقاومت پوسته، ضخامت پوسته، وزن پوسته و شاخص شکل تخم ­مرغ به وسیله تیمارها تحت تأثیر قرار گرفتند (P<0.05). مرغ­های دریافت­کننده 700 میلی­گرم بر کیلوگرم HSLE نسبت به گروه شاهد (44.74 در برابر 47.67) به ­طور معنی­ داری کلسترول زرده را کاهش دادند (P<0.05). نتایج نشان داد که چای ترش می­ تواند در طول دوره اوج تولید، عملکرد تخمگذاری و ویژگی ­های کیفی تخم ­مرغ را بهبود بخشد و کلسترول زرده تخم ­مرغ را کاهش دهد. اثرات سودمند چای ترش بایستی در شرایط تولید تجاری بیشتر مورد بررسی قرار گیرد. Manuscript profile -
Open Access Article
43 - اثر دمای پلت، پروبیوتیک و دانه گندم بر عملکرد رشد، متغیرهای بیوشیمیایی خون، پاسخ سیستم ایمنی و بیان ژن موسین 2 در جوجه های گوشتی
و. ایقانی ع.ا. صادقی س.ن. موسوی پ. جعفری م. چمنیکاندیشنینگ، یک مرحله اصلی در فرآیند پلت کردن خوراک محسوب می­گردد. پروبیوتیک­ها با داشتن توانایی بهبود عملکرد سیستم ایمنی و عملکرد رشد شناخته می­شوند. گندم می­تواند به عنوان یک جایگزین برای ذرت مورد استفاده قرار گیرد. از این رو، مطالعه حاضر با هدف بررسی د Moreکاندیشنینگ، یک مرحله اصلی در فرآیند پلت کردن خوراک محسوب می­گردد. پروبیوتیک­ها با داشتن توانایی بهبود عملکرد سیستم ایمنی و عملکرد رشد شناخته می­شوند. گندم می­تواند به عنوان یک جایگزین برای ذرت مورد استفاده قرار گیرد. از این رو، مطالعه حاضر با هدف بررسی دمای پلت، پروبیوتیک و دانه گندم بر عملکرد رشد، متغیرهای بیوشیمیایی خون، پاسخ سیستم ایمنی و بیان ژن موسین 2 در جوجه­های گوشتی انجام گرفت. تعداد 800 قطعه جوجه یکروزه گوشتی در قالب هشت تیمار و چهار تکرار برای هر تیمار تقسیم­بندی شدند (به ازای هر تکرار 25 قطعه). طرح آزمایشی کاملا تصادفی به صورت فاکتوریل 2 × 2 × 2 براساس دو سطح مصرف گندم (0 و 500 گرم بر کیلوگرم)، دو سطح مصرف پروبیوتیک (0 و 200 میلی­گرم بر کیلوگرم) و دو دمای کاندیشنینگ (70 و 85 درجه سلسیوس) مورد استفاده قرار گرفت. عملکرد رشد، پاسخ سیستم ایمنی، متغیرهای بیوشیمیایی خون و بیان ژن موسین 2 مورد اندازه­گیری قرار گرفت. در رابطه با عملکرد رشد، پاسخ سیستم ایمنی و متغیرهای بیوشیمیایی خون، اثرات اصلی و متقابل معنی­دار نبودند (P<0.05). جیره­های محتوی پروبیوتیک هم بر پایه ذرت و هم بر پایه گندم، باعث افزایش بیان ژن موسین 2 شدند (P<0.05). گندم می­تواند به عنوان یک جایگزین برای ذرت مورد استفاده قرار بگیرد. Manuscript profile -
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44 - Biochemical and Mineral Profile of South Eastern Algerian Desert Goats (Capra hircus)
N. Hafid T. Meziane B. Maamache M. Belkhiri -
Open Access Article
45 - اثر پودر ضایعات گوجه فرنگی روی عملکرد تخمگذاری، کیفیت تخم مرغ، محتوای پروفایل لیپید و کاروتن تخم مرغ در مرغان تخمگذار
M. Habanabashaka M. Sengabo I.O. Oladunjoyeاین مطالعه در طی 8 هفته و برای بررسی اثرات استفاده از پودر ضایعات گوجه فرنگی در جیره مرغان تخمگذار روی عملکرد تخمگذاری، کیفیت تخم مرغ و پروفایل لیپید تخم مرغ و همچنین برای کاهش هزینه خوراک و تولید انجام شد. چهار جیره تخمگذاری حاوی پودر ضایعات گوجه فرنگی در چهار سطح 0، 3 Moreاین مطالعه در طی 8 هفته و برای بررسی اثرات استفاده از پودر ضایعات گوجه فرنگی در جیره مرغان تخمگذار روی عملکرد تخمگذاری، کیفیت تخم مرغ و پروفایل لیپید تخم مرغ و همچنین برای کاهش هزینه خوراک و تولید انجام شد. چهار جیره تخمگذاری حاوی پودر ضایعات گوجه فرنگی در چهار سطح 0، 3، 6 و 9 درصد به طور تصادفی به چهار گروه 40 قطعهای از مرغان در یک طرح کاملاً تصادفی اختصاص یافتند. هر تیمار شامل چهار تکرار و هر تکرار شامل 10 قطعه مرغ بود. دادههای جمعآوری شده توسط رویه GLM بسته نرمافزاری SASآنالیز شدند. نتایج تفاوت معنیداری برای سطوح 0، 3 و 6 درصد از پودر ضایعات در مورد تولید تخممرغ، پروفایل لیپید زرده و محتوای کاروتن آن نشان نداد (به ترتیب 30/68، 80/67 و 10/68 درصد) اما در سطح 9 درصد استفاده از پودر ضایعات کاهش معنیدار در این تولید (45/63 درصد تولید روز مرغ) مشاهده شد. ضریب تبدیل خوراک در سطح 9 درصد به طور معنیداری بالاتر بود. وزن تخممرغ، واحدهاو و شاخص زرده توسط تیمارهای جیرهای تأثیر نپذیرفتند. رنگ زرده به طور معنیداری با افزایش سطح ضایعات در جیرهها افزایش یافت. محتوای لیپیدزرده (از جمله کلسترول) در کمترین مقدار در سطوح 6 و 9 درصد بود. محتوای کاروتنوئید زرده (از جمله لیکوپن) در مرغان تغذیه شده با پودر ضایعات به طور معنیداری با افزایش محتوای ضایعات افزایش یافت. نتیجه اینکه، استفاده از پودر ضایعات گوجه فرنگی تا سطح 6 درصد میتواند بدون اثر سوء روی کیفیت تخم مرغ و میزان تولید تخم مرغ در جیره مرغان تخمگذار استفاده شود. این سطح از پودر ضایعات همچنین نشان داد که از طریق افزایش شاخص رنگ زرده و غلظلت لیکوپن و همچنین کاهش محتوای کلسترول زرده تخممرغ میتواند مفید نیز باشد. Manuscript profile -
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46 - The Effects of Restaurant Residuals in the Diet on General Performance, Egg Characteristics, Blood Parameters and Intestinal Morphology of Japanese Quails
Y. Karimi A.A. Saki H. Jahanian Najafabadi P. Zamani M. Houshyar -
Open Access Article
47 - آنالیز مقایسهای بین اثرات افزودن خوراک با پودر سیر (Allium sativum) و ریشه زردچوبه (Curcuma longa) روی عملکرد مرغان تخمگذار و کیفیت تخم مرغ
م. حاج آید آ. آیسا م. نومیاین آزمایش، در طول یک دوره 7 هفتهای برای بررسی اثرات استفاده از سطوح متفاوتی از پودر سیر و ریشه زردچوبه، روی عملکرد مرغان تخمگذار، ویژگیهای کیفی تخم مرغ و محتوای کلسترول در زرده انجام شد. 216 مرغ تخمگذار سفید نروژی 27 هفتهای بهطور تصادفی به 9 تیمار با 8 تکرار از هرک Moreاین آزمایش، در طول یک دوره 7 هفتهای برای بررسی اثرات استفاده از سطوح متفاوتی از پودر سیر و ریشه زردچوبه، روی عملکرد مرغان تخمگذار، ویژگیهای کیفی تخم مرغ و محتوای کلسترول در زرده انجام شد. 216 مرغ تخمگذار سفید نروژی 27 هفتهای بهطور تصادفی به 9 تیمار با 8 تکرار از هرکدام 3 پرنده اختصاص یافت. آنها با جیرههای غذایی صفر، 0.5، 1، 1.5 و 2 درصد از پودر سیر یا ریشه زردچوبه تغذیه شدند. دادههای عملکرد تخمگذاری، کیفیت تخم مرغ، و محتوای کلی کلسترول در زرده تخم مرغ در تخم مرغها اندازهگیری شد. وزن زنده نهایی بدن، خوراک مصرفی روزانه و نسبت تبدیل خوراک توسط جیرههای مکملسازی شده با پودر سیر و ریشه زردچوبه تحت تأثیر قرار نگرفتند (P≥0.273). هیچ تفاوت معنیداری در تولید تخم مرغ، نرخ تخم مرغهای بدون پوسته و وزن تخم مرغ شناسایی نشد (P≥0.375). با این حال، اضافه کردن 2 درصد پودر سیر نرخ تخم مرغهای شکسته را کاهش داد (P=0.030). مکملسازی پودر سیر و ریشه زردچوبه اثر معنیداری روی نرخ تخم مرغهای دو زرده داشت (P<0.0001). وزن سفیده، قطر و ارتفاع همچنین توسط پودر سیر و ریشه زردچوبه اضافه شده تحت تأثیر قرار گرفتند (P≤0.007). وزن پوسته تخم مرغ در گروه مرغان 1 درصد ریشه زردچوبه (5.64 گرم) سنگینتر از گروههای شاهد و سیر 5 درصد بود. افزودن خوراکی 1 درصد پودر سیر و ریشه زردچوبه غلظت کلسترول زرده تخم مرغ را کاهش داد (P=0.024). در نتیجه، اضافه کردن خوراکی پودر سیر و ریشه زردچوبه میتواند به عنوان جایگزینی برای بهبود کیفیت تخم مرغ در مرغان تخمگذار استفاده شود. Manuscript profile -
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48 - بررسی ارتباط چندشکلی ژن کاپا-کازئین با برخی فراسنجههای خون در گاو بومی گیلان
A. Sobar Poorrajabi Ghaziyani S.Z. Mirhoseini N. Ghavi Hossein-Zadeh Z. Ansari Pirsaraei H. Dehghanzadehارزیابی فراسنجههای بیوشیمیای خون و شیر همواره به عنوان شاخصهایی برای چگونگی سلامت حیوان و محصولات لبنی مرغوب مورد توجه بودهاند. برای بررسی ارتباط ژنوتیپهای مختلف ژن کاپا-کازئین با فراسنجههای خونی 126 رأس گاو بومی گیلان از هر دو جنس به طور تصادفی و انفرادی خونگیری ب Moreارزیابی فراسنجههای بیوشیمیای خون و شیر همواره به عنوان شاخصهایی برای چگونگی سلامت حیوان و محصولات لبنی مرغوب مورد توجه بودهاند. برای بررسی ارتباط ژنوتیپهای مختلف ژن کاپا-کازئین با فراسنجههای خونی 126 رأس گاو بومی گیلان از هر دو جنس به طور تصادفی و انفرادی خونگیری به عمل آمد. با استفاده از روش بهینه شده نمکی DNA نمونهها استخراج شدند.برای اندازهگیری سطوح گلوکز، اوره، کلسترول، تریگلیسرید و تیروکسین از پلاسمای خون استفاده شد. دو آلل A و B به ترتیب با فراوانیهای 726/0، 274/0 و دو ژنوتیپ AA و AB به ترتیب با فراوانی 452/0، 548/0 در جمعیت مشاهد شد. احتمالاً به دلیل کم بودن تعداد نمونهها و فراوانی کم آلل B، ژنوتیپ BB در جمعیت دیده نشد. جمعیت از نقطه نظر این جایگاه ژنی در تعادل هاردی- واینبرگ قرار نداشت. نتایج تجزیه و تحلیلهای آماری نشان داد که بین سطوح گلوکز، کلسترول و تیروکسین در هر دو جنس اختلاف معنیدار وجود دارد که به میزان بسیار زیادتر غلظت هورمون تستوسترون، هورمونهای تیروئیدی در جنس نر نسبت به جنس ماده مرتبط است، اما سطوح تریگلیسرید و اوره اختلاف معنیداری از خود نشان ندادند (05/0=α). ژنوتیپهای AA و AB ژن کاپا-کازئین در گاو بومی گیلان از نظر غلظت فراسنجههای خونی گلوکز، اوره، کلسترول، تریگلیسرید و تیروکسین تفاوت معنیداری با یکدیگر نداشتند (05/0=α). با توجه به مشاهدات و نتایج حاصل چندشکلی ژن کاپا-کازئین به تنهایی نمیتواند نشانگر مناسبی برای غلضت این قبیل فراسنجههای خونی بر روی گاو بومی گیلان باشد. Manuscript profile -
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49 - Effects of Horsetail (Equisetum arvense), Vitamin C and Organic Zinc Supplements on Growth Performance, Carcass Yield, Serum Biochemical Values and Antioxidant Status of Broiler Chickens
S. Azimi-Youvalari M. Daneshyar S.M. Abtahi-Froushani S. Payvastegan -
Open Access Article
50 - Investigation of Cadmium on Some Biochemical Indices of the Farmed Silver Carp (Hypophthalmichthys molitrix)
Mahzad Shakoori S. Abdali S. ShokohiThe aim of this study was to evaluate the toxicity effect of Cadmium heavy metal on some serological parameters of Silver carp which have been in the vicinity of cadmium for a short term. In this study a total of 135 fish with mean weight of 50±10grand mean lengt MoreThe aim of this study was to evaluate the toxicity effect of Cadmium heavy metal on some serological parameters of Silver carp which have been in the vicinity of cadmium for a short term. In this study a total of 135 fish with mean weight of 50±10grand mean length of 13±1cm were placed in 9 aquariums of 90-liter capacity, in contact with 0.5 and 10 mg/L of CdCl2.Sampling of fishwas done randomly every 12 hours until 96 hours from caudal vein. The results showed that, the level of triglyceride in 24 and 48 hours decreased significantly, but showed no significant increase in 72 hours. The level of cholesterol increased significantly at 72 and 96 hours with increasing the concentration of cadmium (P<0/05). Glucose level increased significantly in 72 hours, but significantly decreased with increasing the concentration of cadmium in 72 and 96 hours (P<0/05). The level of total protein decreased significantly in 24 and 96 hours with increasing the concentration of cadmium, and in 72 hours increased significantly (P<0/05). The level of albumin increased significantly in 96 hours. Based on these results, biochemical parameters are useful for monitoring of cadmium acute toxicity in Silver Carp. Manuscript profile -
Open Access Article
51 - Investigation of Zinc on some biochemical indices of the farmed Silver carp (Hypophthalmichthys molitrix)
M. Shakoori S. Abdali H. Negarestan The aim of this study was to evaluate the toxicity effect of zinc heavy metal on some serological parameters on Silver carp in the vicinity with zinc in short term. In order to do this study a total of 135 fish with mean weight 50±10gr and mean length 13& More The aim of this study was to evaluate the toxicity effect of zinc heavy metal on some serological parameters on Silver carp in the vicinity with zinc in short term. In order to do this study a total of 135 fish with mean weight 50±10gr and mean length 13±1cm were located to adjacent to 0.5 and 10 mg/L of Zn (NO3)2 in 9 Aquarium with 90 liter of capacity.Sampling of fish was done randomly each 12 hours until 96 hours from caudal vein. The result showed that the level of cholesterol in 10 mg/L treatments in 96 hours were significant difference with 5 mg/ L and control treatments (p<0/05). The results showed that the minimum amount of cholesterol in 10 mg/L treatment in 96 hours was (10.83±0.2 mg/ dL) and the maximum amount was found in 5 ppm treatment in 48 hours was (102.7±22.7 mg/dL). Mean triglyceride fluctuated, so that the maximum amount of triglyceride was found in 10 mg/L treatment in 12 hours (93±14) mg/dL) and the minimum in 96 hours in 5 mg/L treatment was (24.4±2 mg dl). By increasing the concentration of zinc. albumin level were increased significantly. The minimum amount was found in control treatment which was (0.73±0.14 g/dL) and the maximum level in 5 m/g/L treatment at 96 hours was (9.03±0.6 g/dL). Total protein levels were decreased significantly (p<0.05). The minimum amount of total proteins in 5 mg/L treatment at 96 hours was (0/043±0/003) g/dL, and the maximum amount was at 12 hours in 10 mg/L treatment at (3/53±0/3)g/dL. Based on results, Hematological and biochemical parameters are useful for monitoring of Zinc acute toxicity in Silver carp. Manuscript profile -
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52 - The Effect of Consumption the Alcoholic Extract of Cedar on Blood Glucose, Urea and Total Cholesterol Diabetic Rats
Mostafa Bahrebar Yadolah Edalatpanah -
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53 - Carvacrol Attenuates Disrupted Lipid Profile Induced by Organophosphates in Male Wistar Rat: a Comparative Toxicity
Ali Salari Kambiz Roshanaei Bahram Rasoulian Javad Khalili Fard -
Open Access Article
54 - Comparison of Six Weeks of Weight Training with a Combination of Beta‑hydroxy‑Beta‑methylbutyrate and Creatinine and Two Weeks of Non-training on the Concentrations of some Blood Biochemical Factors in Male Powerlifting Athletes
Mojtaba Darvishkhadem Tahereh Bagherpour Nematollah Nemati -
Open Access Article
55 - Comparative Study on Cholesterol Content and Physicochemical Properties of Some Branded and Unbranded Commercial Edible Oils in Khulna, Bangladesh
Md. Hasan Md. Hossain Palash Dhar Md. Haque -
Open Access Article
56 - The Effect of Diets Supplemented with Vitamins C and E on Plasma Cholesterol in Adult Sterlet, Acipenser ruthenus
مصطفی تاتینا محمود بهمنی مهدی سلطانی مهتاب قریب خانیThis study was conducted in order to characterize the different levels of dietary vitamin Cand vitamin E on plasma cholesterol of sterlet in propagation center of Sturgeon Research Institute. Nine experimental diet including threelevels of vitamin E, D-alpha-tocopherol, MoreThis study was conducted in order to characterize the different levels of dietary vitamin Cand vitamin E on plasma cholesterol of sterlet in propagation center of Sturgeon Research Institute. Nine experimental diet including threelevels of vitamin E, D-alpha-tocopherol, (0, 100 and 400 mg kg1- diet) andthreelevels of vitamin C, L-ascorbyl-2-polyphosphate, (0, 100 and 400 mg kg1- diet) wereprepared and used for feeding fish in two replicates for 15 weeks. After fish adaptations with artificial food, 15 sterlets (Acipenser ruthenus) with the average weight of 350.92andplusmn;14.28g were divided into 18 tanks. The fish were fed 2% their wet body weighs. Blood samples were obtained from three fish of each tank at the end of week 5 and week 15. The results of blood analysis showed that the highest amount of cholesterol at the end of week 5 was observed in E0 C100 mg/kg and E100 C400 mg/kg treatments (diets 2 and 6) and at the end of week 15 was observed in E100 C0 mg/kg treatment (diet 4) (Pandlt;0.05). On the other hand the lowest amount of cholesterol at the end of week 5 and week 15 was observed in E100 C100 mg/kg (diet 5) and E400 C100 mg/kg (diet 8), respectively (Pandlt;0.05). The results of this study revealed that different levels of vitamin C and vitamin E may have some effects on cholesterol fluctuations of sterlet Manuscript profile -
Open Access Article
57 - Effect of Palmatyn Hydrochloride on Some of Serum Biochemical Parameters in Streptozotocin-induced Diabetic Rats ر
پیراسته نوروزی حمید کلالیان مقدم ویدا حجتیDiabetesis a metabolic disorder that gripped mankind since time immemorial has been the world's top. Oxidative stress is the result of diabetes and its complications in a large amount of communication. Antioxidants, especially of plant origin are very important in the p MoreDiabetesis a metabolic disorder that gripped mankind since time immemorial has been the world's top. Oxidative stress is the result of diabetes and its complications in a large amount of communication. Antioxidants, especially of plant origin are very important in the prevention of diabetes complications.The aim of this study was to evaluate the effect on the Hydrochloride Palmatyn biochemical parameters in streptozotocin-induced diabetic rats is. In this study, 32 male Wistar rats weighing approximately 240 g, were randomly selected and divided into four groups: contro l, non-diabetic Palmatine treated, diabetic and hydrochloride Palmatine diabetic.Intraperitoneal injection of 55 mg/kg streptozotocin diabetes was induced.One week after injection, treated with hydrochloride Palmatine 10mg/kg/Day dose for six weeks and injections were performed. Testicular damage by hematoxylin - eosin specified Vfaktvrhay Vhvrmvny biochemical blood was measured.Data Software prism-5.0-test were analyzed by one way ANOVA and Tukey.The results show that diabetes induced oxidative stress and production of free radicals increase glucose and reducing the secretion in blood insulin, cholesterol and triglyceride abnormalities are disorder.Palmatynin samples treated with these complications improved, the levels of glucose, cholesterol, triglycerides decreased P ≤ 0.001)) Outer hyperinsulinemia (P ≤ 0.001) is. Considering the obtained results, it was found that Palmatine hydrochloride low creators effect on blood glucose and lipid in diabetic rats, the effect can be to reduce the effects of cardio - vascular disease caused by diabetes mellitus be considered. ر Manuscript profile -
Open Access Article
58 - An Investigation of Creatine Kinase Enzyme (CKMB) and Cholesterol in Type 1 and2 Diabetic Mellitus in Gonbad'e Kavoos
N. Arabsarhaddi N. Masoudian H. Abbaspour E. Naghipoor M. FakhreddinnejadThe person who suffered from type 1 and type 2 Diabetics are more deserved to cardiovascular disease. High ratio of morbidity and mortality can be attributed to the cardiovascular diseases. Measuring CKMB's level along with CPK is considered as specialized test to diagn MoreThe person who suffered from type 1 and type 2 Diabetics are more deserved to cardiovascular disease. High ratio of morbidity and mortality can be attributed to the cardiovascular diseases. Measuring CKMB's level along with CPK is considered as specialized test to diagnose the cardiovascular damages and also to determine the possibility of myocardial attacks. The present study aimed to compare the level of CKMB and cholesterol in type 1 with type 2 diabetics. Population is consisted of diabetic's persons in Gonbad Kavoos. One hundred diabetic (50 persons type 1 and fifty person type 2) were selected as experiment group and 50 healthy persons were selected as control group. After separating blood plasma and measuring its level of glucose, cholesterol and CKMB, the spectrophotometer and auto analyzer were used to read the data. The data were analyzed by SAS. The results have shown that the level of cholesterol in type 1 diabetics was higher than type 2. Also, CKMB in type 2 diabetic male is higher than type 1 diabetic male but the level of CKMB in type 1 and type 2diabetics female was nearly the same. The results also have shown that the level of glucose in type 1 diabetics (both male and female) was higher than type 2. According to the obtained result it may be concluded that higher rate of glucose, cholesterol and CKMB in type 1 diabetics than the type 2 is related to the higher rate of morbidity and mortality. Manuscript profile -
Open Access Article
59 - The Efect of Adding Prebiotic, Synbiotic and Phytobiotic Supplements in the Diet on Growth Performance, Carcass Traits, Apparent Digestibility of Nutrients and Some Blood Parameters of Fattening Zell Lambs
Mehdi Saravani Mohsen Hajipour Kaveh Jafari Khorshidi Seyed Makan Mousavi Kashani Parvin ShawrangIn this study, the effect of adding prebiotic, synbiotic and phytobiotic supplements in the diet on growth performance, carcass traits, apparent digestibility of nutrients and some blood parameters of fattening Zell lambs was investigated. For this purpose, 24 Zell male MoreIn this study, the effect of adding prebiotic, synbiotic and phytobiotic supplements in the diet on growth performance, carcass traits, apparent digestibility of nutrients and some blood parameters of fattening Zell lambs was investigated. For this purpose, 24 Zell male lambs with an avrage age of about 5 months and an avrage weight of 25.4±0.50 were used for 90 days. The experimental treatments included 1- control group (no supplement), 2- treatment containing 2 g of A-Max prebiotic supplement, 3- treatment containing 4 g of Biomin IMBO synbiotic supplement, and 4- treatment containing 6 g of Bioherbal phytobiotic supplement per head of lamb per day. The growth performance results showed that there was a significant difference between the experimental treatments in the fattening weight, dry matter intake, daily weight gain and feed conversion ratio (p < 0.05). The highest weight at the end of the fattening period, dry matter intake and daily weight gain were observed in the treatment of 4 g of synbiotic supplement. The treatment with 6 g of phytobiotic supplement had the lowest feed conversion ratio. The highest apparent digestibility of dry matter, NDF and ADF was observed in the treatment of 4 g of synbiotic supplement (p < 0.05). The results of some blood serum parameters showed that there was a significant difference in the concentration of glucose, cholesterol, triglyceride and blood urea nitrogen between the experimental treatments (p < 0.05). The highest concentration of glucose was in the treatment of 4 g of synbiotic supplement, the lowest concentration of cholesterol was in the treatment of 6 g of phytobiotic supplement. Blood urea nitrogen had the lowest concentration in the treatment of 4 g of synbiotic supplement. The treatment with 4 g of synbiotic supplement had the highest hot carcass weight, hot carcass percentage, cold carcass weight, cold carcass percentage, thigh percentage and shoulder percentage (p < 0.05). The present research showed that the addition of 4 g of synbiotic supplement in the diet improved the growth performance, valuable parts of the carcass and the apparent digestibility of nutrients in fattening lambs. Manuscript profile -
Open Access Article
60 - Effects of Eight Weeks of High-Intensity Interval Training (HIIT) on the Expression of GPR120 and AMPK Proteins in the Heart Tissue of Diabetic Male Rats
Ebrahim Hoseini Houri pasand Saeid Dabbagh Nikoo Kheslat Javad VakiliThe reverse cholesterol transfer process has a positive role in reducing atherosclerotic plaques during diabetes. Therefore, the aim of the present study was to evaluate the effect of eight weeks of high-intensity interval training on GPR120 and AMPK proteins in the car MoreThe reverse cholesterol transfer process has a positive role in reducing atherosclerotic plaques during diabetes. Therefore, the aim of the present study was to evaluate the effect of eight weeks of high-intensity interval training on GPR120 and AMPK proteins in the cardiac tissue of mice with type 2 diabetes. In an experimental study, 40 three-month-old adult male Wistar rats with an average weight (250-300 g) were randomly divided into four groups of 10 series including: healthy control (C: intraperitoneal injection of saline), healthy training (T: running at 85-90 % of maximum speed in 6 to 12 bouts in two-minute periods; 5 days per week for eight weeks), diabetic control (D: diabetic on a high-fat diet with intraperitoneal injection of streptozotocin) and trained diabetics (D+T: diabetic with training) were divided. A method based on Western blotting was used to determine changes in the expression profile of GPR120 and AMPK proteins in the heart muscle tissue (left ventricle) of rats. The two-way analysis of variance and Bonferroni post hoc test were used to analyze the data. Induction of diabetes (D) significantly reduced GPR120 and AMPK proteins (p ≤ 0.05). While HIIT training apply in healthy group (T) increased 81% and 47% in GPR120 and AMPK compared to diabetic control group (D) respectively (p = 0.001). Also, training intervention has the ability to prevent a decrease in both of proteins in the trained diabetic group (D+T) compared to the diabetic group (D) (p = 0.023). Based on the findings of this study, it can be stated that eight weeks of high-intensity interval training (HIIT) is a preventive strategy against reducing the activity of GPR120 and AMPK proteins involved in the reverse cholesterol transmission during type 2 diabetes. Manuscript profile -
Open Access Article
61 - Effect of Alcoholic Extract of Artichoke Leaves on Triglyceride and Blood Cholesterol Levels following Inhalation Toxicity in Male Rats
N. Khosravizad Gh. Vaezi N. Hayati RoudbariIncreased levels of blood cholesterol and triglyceride have many implications for humans and sufferers suffer from high costs annually. This research was conducted to investigate the effect of leaf extract of artichoke after lead inhalation in triglyceride and cholester MoreIncreased levels of blood cholesterol and triglyceride have many implications for humans and sufferers suffer from high costs annually. This research was conducted to investigate the effect of leaf extract of artichoke after lead inhalation in triglyceride and cholesterol levels in rats. In the first day, 5 groups of 6 male adult rats were contracted except for the control group under the lead inhalation. From the first day, 5 mg of extract gavage in the experimental groups at concentrations of 25, 50 and 100 mg/kg Mice weight was measured for 10 days. On the 10th day, the blood was collected from the heart and the remaining blood was separated and frozen with triglyceride and cholesterol kits for measurement. In this method (SPSS software, mean ± SD) method and Tukey test were used for data analysis.Blood cholesterol and triglyceride levels were determined by special kit after lead inhalation in the blood and after application of artichoke extract, p≤ 0.001 was statistically significant. The result was a decrease in the blood cholesterol and triglyceride levels in the artichoke leaf extract.due to its high antioxidant properties, leaf extract can reduce blood cholesterol and triglyceride levels. Therefore, Artichoke can be useful for reducing blood glucose in daily diet. Manuscript profile -
Open Access Article
62 - Effects of 8-weeks cinnamon intake with and without high intensity interval training on blood lipids profile in overweight girls of aged-high school
Saber Rezanejad Mina Tarahhomi Akram khani Rozveh Mehdi KargarfardBackground: Obesity and overweight are among the most common complications among high school students, which can be associated with cardiovascular diseases. Modifying the lifestyle through sports activities and herbal medicines is one of the solutions to combat this pro MoreBackground: Obesity and overweight are among the most common complications among high school students, which can be associated with cardiovascular diseases. Modifying the lifestyle through sports activities and herbal medicines is one of the solutions to combat this problem. The purpose of this study was to evaluate the effect of an 8-week cinnamon consumption with and without high-intensity interval training on blood lipid profiles in high school-aged overweight girls.Methods: In this semi-experimental study with a pre-test and post-test design, 36 overweight women aged 15-18 years were randomly assigned to one of the 3 groups: intense interval training (n=12), cinnamon supplementation (n=12) and intense interval training+cinnamon (n=12). The intense interval training program was conducted three times a week for 8 weeks in the two intervention groups. Each session, lasting 30-35 minutes, involved high-intensity exercises at 90-95% of peak oxygen consumption. Diet groups received cinnamon supplements at the rate of 6 grams/day for a period of 8 weeks. Body measurements (weight, body mass index) and serum levels of blood fats (cholesterol, triglyceride, high-density lipoprotein, low-density lipoprotein) were measured before and after the study. The data were analyzed using the dependent t-test and analysis of covariance at a level less than 0.05.Results: After 8 weeks of intervention, a significant decrease in body weight and body mass index and a significant increase in HDL cholesterol were observed in the intense interval training and intense interval training + cinnamon groups compared to the cinnamon alone group (p≤0.05). However, Bonferroni's follow-up test did not show significant differences in cholesterol, triglyceride and low-density lipoprotein levels between the groups (p≥0.05).Conclusion: High-intensity intermittent exercise with cinnamon consumption can reduce body composition and some blood lipids more effectively than cinnamon supplementation in overweight high school girls. Manuscript profile -
Open Access Article
63 - The effects of liposuction surgery on metabolic factors
Nasser sanjar mussavi Ahmad saffari Shahedeh karimi torshizi Arezou FarajpourBackground: Today, obesity has become a common and chronic disease can also endure socio - economic losses and serious health problems brought abundant. Obesity causes various diseases such as diabetes, hypertension, dyslipidemia, coronary heart disease and so on.There MoreBackground: Today, obesity has become a common and chronic disease can also endure socio - economic losses and serious health problems brought abundant. Obesity causes various diseases such as diabetes, hypertension, dyslipidemia, coronary heart disease and so on.There are several treatments for patients suffering from obesity but due to vast changes in life style, the patients look for easier, faster and safer techniques with long lasting results. The liposuction is one of the most popular techniques for treating localized obesity in recent years. In this study, we examined the metabolic changes following liposuction surgery. Materials and methods: This cross-sectional study was done during 2013-2014 on 19 obese- non-diabetic women (BMI≥30 kg/m2). For Eligible patients, history and physical examination were recorded and BMI was calculated. Informed consent was obtained. Fasting blood samples of patients were taken 24 hours before surgery and 4 weeks after surgery for FBS, Total Chol, HDL, LDL, TG and Insulin was measured.Demographic data and laboratory data were analyzed using SPSS 20 software and paired t-test. Results: The findings showed that the FBS and insulin significantly decreased and TG significantly increased after liposuction, while changes in total cholesterol, LDL and HDL were not statistically significant. Conclusion: Due to a decrease in insulin levels and FBS somewhat decreased serum lipids after liposuction, this surgery can improve insulin sensitivity, blood lipid profile and improving the quality of life in these patients. Manuscript profile -
Open Access Article
64 - Studying the Concentration of Glucose, Urea and Cholesterol in Blood Serum and Follicular Fluid of Different-Sized Follicles in Hybrid Cows of Khouzestan Province
کمال Hasanpoor, محمد تقی Tagi Begi Nasiri, منصور Khezri, , M. Asghari Moghadam A. Karamzade, M. Amrai,Improvement of the fertility and reproductive status of cows necessitates having suffcient knowledge of the ovary of this animal species. Ovarian follicular activities play a signifcant role in controlling reproductive cycle, ovulation and pregnancy. The present study MoreImprovement of the fertility and reproductive status of cows necessitates having suffcient knowledge of the ovary of this animal species. Ovarian follicular activities play a signifcant role in controlling reproductive cycle, ovulation and pregnancy. The present study aims to compare the concentration of glucose, urea and cholesterol of ovarian follicular fluid in different-sized follicles with the blood serum of hybrid cows. Blood samples and ovaries of 20 slaughtered cows were examined. The follicular fluid was obtained from 3 follicular groups of small (3-5mm), average (6-9mm) and large (10mm or more) sizes. Concentration of glucose, urea and cholesterol in follicular fluids and blood serum was determined. The results showed that concentration of glucose, urea and cholesterol in blood serum was signifcantly higher than that of the large, average-sized and small follicles. Glucose concentration of large follicles was signifcantly higher than that of the average-sized and small follicles (P < 0.05). However, no signifcant difference was observed between the average-sized and small follicles. Urea level decreased as the follicle size increased. Cholesterol concentration of small follicles was signifcantly higher than that of the large and average-sized follicles (P < 0.05). However, no signifcant difference was observed between the large and average-sized follicles. Overall, the results showed that ovarian follicle size grows and matures in a changing biochemical environment. This environment is associated with the changes in blood glucose level. Moreover, urea and cholesterol levels decrease as the follicle size increases. Manuscript profile
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