Subject Areas : biology
1 - Assistant Professor, Department of Biology, Qom Branch, Islamic Azad University, Qom, Iran.
Keywords: Lipexan capsule, cholesterol, triglyceride, LDL, Gemfibrozil, Herbal capsules, Mouse.,
Abstract :
Purpose: The role of plants in reducing blood lipids and thus reducing the risk of cardiovascular diseases is known. In this regard, the aim of the current study is to investigate the effect of Lipexan capsules in reducing triglycerides, cholesterol and LDL in an animal model.
Materials and methods: In this research, 40 male Wistar rats with an approximate weight of 200±20 grams were used. Mice were randomly divided into 5 groups of 8, including the control group with diet and the control group with high-fat diet (for 21 days), the treatment group with lipexan capsules with a dose of 90, the treatment group with lipexan capsules with a dose of Min and the treatment group with Fibrozil jam capsules (for 30 days) were divided. Blood sampling was done at the end. Cholesterol, triglyceride and LDL values were measured. One-way analysis of variance was used to analyze the data.
Findings: The serum concentrations of cholesterol, triglyceride and LDL in the groups treated with Lipexan Min and 90 capsules and the Fibrozil Jam group were significantly reduced compared to the control group with standard food and the control group with high-fat food.
Conclusion: Lipexan capsule has an effect on the concentration of cholesterol, triglyceride and LDL in hyperlipidemic rats. Lipexan capsules can be used to reduce the level of blood lipids, as an effective treatment or prevention method for hyperlipidemia.
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