Evaluation of cholesterol lowering property of selected herbs in ghee (heat clarified milk fat)

Subject Areas : Phytochemistry: Isolation, Purification, Characterization

Krupaben M.  Shingala ¹ (Dairy Chemistry Department, SMC College of Dairy Science, Anand Agricultural University (AAU), Anand, Gujarat, India)
Rayan V.  Lunagariya ² (Dairy Chemistry Department, SMC College of Dairy Science, Anand Agricultural University (AAU), Anand, Gujarat, India)
Bhavbhuti M.  Mehta ³ (Dairy Chemistry Department, SMC College of Dairy Science, Anand Agricultural University (AAU), Anand, Gujarat, India)
V.B.  Darji ⁴ (Department of Agricultural Science, CAIT, AAU, Anand, Gujarat, India)
K.D.  Aparnathi ⁵ (Dairy Chemistry Department, SMC College of Dairy Science, Anand Agricultural University (AAU), Anand, Gujarat, India)

Received: 2019-04-26 Accepted : 2019-08-26 Published : 2019-09-01

Keywords:

References:

Belichovska, D., Pejkovski, Z., Belichovska, K., Uzunoska, Z., Silovska Nikolova, A. 2017. Effect of Vegetable Oils on Fatty Acid Composition and Cholesterol Content of Chicken Frankfurters. IOP Conference Series: Earth and Environmental Science, 85, pp. 1-6.

Bhatia, P., Sharma, V., Arora, S., Rao, P.S., 2019. Effect of cholesterol removal on compositional and the physicochemical characteristics of anhydrous cow milk fat (cow ghee). Int. J. Food Prop. 22(1), 1-8.

Bhatted, S., Singh, G. 2002. A National Seminar on “Role of Pure Ghee in Health and Nutrition-Exploding Myths. Jointly organized by Indian Dairy Association Gujarat Chapter, Anand and Gujarat Co-operative Milk Marketing Federation Ltd., Anand and J S Ayurveda College, Nadiad, pp. 19-22.

Borradaile, N.M., Carroll, K.K., Kurowska, E.M., 1999. Regulation of HepG2 cell apolipoprotein B metabolism by the citrus flavanones hesperetin and naringenin. Lipids 34,591-598.

Camilo, C.J., Alves Nonato, C.d.F., Galvão-Rodrigues, F.F., Costa, W.D., Clemente, G.G., Sobreira Macedo, M.A.C., Galvão Rodrigues, F.F., da Costa, J.G.M., 2017. Acaricidal activity of essential oils: a review. Trends Phytochem. Res. 1(4), 183-198.

Chandrasekara, N., Shahidi, F., 2011. Effect of roasting on phenolic content and antioxidant activities of whole cashew nuts, kernels, and testa. J. Agric. Food Chem. 59, 5006-5014.

Cook, N.C., Samman, S., 1996. Flavonoids-chemistry, metabolism, cardioprotective effects, and dietary sources. J. Nut. Biochem. 7, 66-76.

Davidson, S., 1990. Low-cholesterol milk and eggs. Rural Res. 148, 27-28.

De, S., 2004. Outlines of Dairy Technology.19^th Ed., Oxford Publishing Company, New Delhi.

Dunkley, W.L., 1982. Reducing fat in milk and dairy products by processing. J. Dairy Sci. 65, 454-458.

Fletouris, D.J., Botsoglou, N.A., Psomas, I.E., Mantis, A.I., 1998. Rapid determination of cholesterol in milk and milk products by direct saponification and capillary gas chromatography. J. Dairy Sci. 81, 2833-2840.

Frezza, C., Venditti, A., Serafini, I., Carassiti, A., Foddai, S., Bianco, A., Serafini, M., 2017. Phytochemical characteristics of Galeopsis ladanum subsp. angustifolia (Ehrh. ex Hoffm.) Gaudin collected in Abruzzo region (Central Italy) with chemotaxonomic and ethnopharmacological implications. Trends Phytochem. Res. 1(2), 61-68.

Fuhrman, B., Volkova, N., Kaplan, M., Presser, D., Attias, J., Hayek, T., Aviram, M., 2002. Antiatherosclerotic effects of licorice extract supplementation on hypercholesterolemic patients: increased resistance of LDL to atherogenic modifications, reduced plasma lipid levels, and decreased systolic blood pressure. Nutrition 18, 268-273.

Ganguli, N.C., Jain, M.K., 1973. Ghee: Its chemistry, processing and technology. J. Dairy Sci. 56, 19-25.

Geetha, K., 2013. Studies on Anti-hyperlipidemic and Anti-atherosclerotic Activities of Selected Indian Medicinal Plants. Doctoral thesis, Andhra University, Visakhapatnam, India.

Gerard, K.A., Roberts, J.S., 2004. Microwave heating of apple mash to improve juice yield and quality. LWT-Food Sci. Technol. 37, 551-557.

Ghasi, S., Nwobodo, E., Ofili, J.O., 2000. Hypocholesterolemic effects of crude extract of leaf of Moringa oleifera Lam in high-fat diet fed Wistar rats. J. Ethnopharmacol. 69, 21-25.

Gulcin, D., 2006. Antioxidant and antiradical activities of L-carnitine. Life Sci. 78, 803-811.

Igara, C.E., Omoboyowa, D.A., Ahuchaogu, A.A., Orji, N.U., Ndukwe, M.K., 2016. Phytochemical and nutritional profile of Murraya koenigii (Linn) Spreng leaf. J. Pharmacogn. Phytochem. 5(5), 07-09.

Igual, M., García-Martínez, E., Camacho, M.M., Martínez-Navarrete, N., 2011. Changes in flavonoid content of grapefruit juice caused by thermal treatment and storage. Innov. Food Sci. Emerg.Technol. 12(2), 153-162.

Irina, I., Mohamed, G., 2012. Biological Activities and Effects of Food Processing on Flavonoids as Phenolic Antioxidants. In: Advances in Applied Biotechnology (Ed. Marian Petre), InTech Europe, Croatia, pp. 101-124.

Jain, P.G., Patil, S.D., Haswani, N.G., Girase, M.V., Surana, S.J., 2010. Hypolipidemic activity of Moringa oleifera Lam., Moringaceae, on high fat diet induced hyperlipidemia in albino rats. Rev. Bras. Farmacogn. 20, 969-973.

James, M.R., Xian-Liu, Z., Najla, G., 2007. Effect of citrus flavonoids and tocotrienols on serum cholesterol levels in hypercholesterolemic subjects. Altern. Ther. Health Med. 13, 44-48.

Kassaian, N., Azadbakht, L., Forghani, B., Amini, M., 2009. Effect of fenugreek seeds on blood glucose and lipid profiles in type 2 diabetic patients. Int. J. Vitam. Nutr. Res. 79, 34-39.

Koriem, K.M.M., 2014. Antihyperlipidemic activity of the medicinal plants among Kadazan and Dusun communities in Sabah, Malaysia: a review. Asian Pac. J. Trop. Biomed. 4, 768-779.

Larsen, J.E., Froning, G.W., 1981. Extraction and processing of various components from egg yolk. J. Poult. Sci. 60, 160-167.

Mohammadhosseini, M., 2017. The ethnobotanical, phytochemical and pharmacological properties and medicinal applications of essential oils and extracts of different Ziziphora species. Ind. Crop Prod. 105, 164-192.

Mohammadhosseini, M., Akbarzadeh, A., Flamini, G., 2017a. Profiling of compositions of essential oils and volatiles of Salvia limbata using traditional and advanced techniques and evaluation for biological activities of their extracts. Chem. Biodivers. 14.

Mohammadhosseini, M., Sarker, S.D., Akbarzadeh, A., 2017b. Chemical composition of the essential oils and extracts of Achillea species and their biological activities: A review. J. Ethnopharmacol. 199, 257-315.

Mohammadhosseini, M., Venditti, A., Sarker, S.D., Nahar, L., Akbarzadeh, A., 2019. The genus Ferula: Ethnobotany, phytochemistry and bioactivities - A review. Ind. Crops Prod. 129, 350-394.

Nicoliy, M.C., Anese, M., Parpine, M., 1999. Influence of processing on the antioxidant properties of fruit and vegetables. Trends Food Sci. Technol. 10, 94-100.

Oakenfull, D.G., Pearce, R.J., Sidhu, G.S., 1991. Low-cholesterol dairy products. Aust. J. Dairy Technol.46,110-112.

Odriozola-Serrano, I., Soliva-Fortuny, R., Martín-Belloso, O., 2008. Phenolic acids, flavonoids, vitamin C and antioxidant capacity of strawberry juices processed by high-intensity pulsed electric fields or heat treatments. Eur. Food Res. Technol. 228(2), 239.

Ong, C.P., Lee, H.K., Li, S.F.Y., 1990. Supercritical fluid extraction and chromatography of cholesterol in food samples.  J. Chromatogr. A, 515, 509-513.

Rasineni, G.K., Siddavattam, D., Reddy, A.R., 2008. Free radical quenching activity and polyphenols in three species of Coleus. J. Med. Plants Res. 2, 285-291.

Risdian, C., Widowati, W., Mozef, T., Wargasetia, T.L., Khiong, K., 2011. Free radical scavenging activity of ethanolic leaves extract and its different solvent fractions of Piper betle L. in vitro. Indones. J. Cancer Chemoprev. 2, 141-145

Rudolf, J.F., Donna, M., William, J.W., 2010. Statistical Methods, 3^rd Ed., Elsevier Inc., UK.

Sadovoy, V.V., Aralina, A.A., Shchedrina, T.V., 2013. Computer simulation of the mechanism of interaction of red grape flavonoids with cholesterol. Russ. Agric. Sci. 39, 370-372.

Shamala, S., Baskaran, G., Noor, A.S., Siti, A.A., Mohd, Y.S., 2014. Antiartherosclerotic effects of plant flavonoids. BioMed Res. Int. 2014, 1-11.

Sharma, R.S., 1981. Ghee: A resume of recent researches. J. Food Sci. Technol. 18(2), 70-77.

Shingla, K.M., Mehta, B.M., 2018. Cholesterol and its oxidation products: occurrence and analysis in milk and milk products. Int. J. Health, Animal Sci. Food Safety 5, 13-39.

Srinivasan, M.R., 1976. Ghee making in the tropical countries and possibilities of its industrial production. Indian Dairyman 28, 279-283.

Sweeney, J.P., Weihrauch, J.L., 1976. Summary of available data for cholesterol in foods and methods for its determination.  Crit. Rev. Food Sci. Nutr. 8, 131-159.

Thirumalai, T., Tamilselvan, N., David, E., 2014. Hypolipidemic activity of Piper betel in high fat diet induced hyperlipidemic rat. J. Acute Dis. 14, 131-135.

Viña, S.Z., Chaves, A.R., 2008. Effect of heat treatment and refrigerated storage on antioxidant properties of pre‐cut celery (Apium graveolens L.). Int. J. Food Sci. Tech. 43, 44-51.

Wansi, J.D., Sewald, N., Nahar, L., Martin, C., Sarker, S.D., 2018. Bioactive essential oils from the Cameroonian rain forest: A review - Part I. Trends Phytochem. Res. 2(4), 187-234.

Wansi, J.D., Sewald, N., Nahar, L., Martin, C., Sarker, S.D., 2019. Bioactive essential oils from the Cameroonian rain forest: A review - Part II. Trends Phytochem. Res. 3(1), 3-52.

Watanabe, K.H., Aihara, H., Nakamura, R., 1989. Properties of the purified extracellular cholesterol oxidase from Rhodococcus equi No. 23. J. Agric. Food Chem. 37, 1178-1182.

Yu, J., Ahmedna, M., Goktepe, I., 2005. Effects of processing methods and extraction solvents on concentration and antioxidant activity of peanut skin phenolics. Food Chem. 90, 199-206.

Zielinski, H., Michalska, A., Amigo-Benavent, M., del Castillo, M.D., Piskula, M.K., 2009. Changes in protein quality and antioxidant properties of buckwheat seeds and groats induced by roasting. J. Agric. Food Chem. 57, 4771-4776.