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Open Access Article
1 - Investigating the impact of the smart skin according to the location of the user on the amount of energy consumption in cold climate office use (case example of Tabriz city)
zohre salavati majid shahbazi Zohreh TarabiThe shell of the building is one of the most key components of the building. Windows, which are part of the building shell, can play a significant role in reducing energy consumption and increasing the efficiency of natural lighting, which increases the health of the en MoreThe shell of the building is one of the most key components of the building. Windows, which are part of the building shell, can play a significant role in reducing energy consumption and increasing the efficiency of natural lighting, which increases the health of the environment and users. But this does not mean that natural lighting will always reduce energy consumption, but it depends on many parameters. Today, the use of smart and moving facades to improve the light received by residents is known as an effective solution. In this research, the effect of smart facades on the amount of energy consumption in an office room in a cold climate has been investigated. In this research, the goal of the researchers is not to design a shell, but to provide a parametric method to reduce energy consumption. Therefore, the effectiveness or not of this method compared to its traditional mode, i.e. using curtains, has been evaluated. For this purpose, 5 different modes without curtain, closed curtain and three smart shell modes which are arranged in different types have been done. The results show that in the proposed modes of the smart shell, the energy consumption on the south and east fronts has improved by 40% and 65%, respectively, compared to the mode with curtains. Manuscript profile -
Open Access Article
2 - Sensitivity Analysis of Constructional Specifications on Thermal Performance of Naturally Ventilated Box Window Double Skin Facade in Hot Arid Climate of Iran (Tehran)
Faryal sadat Siadati Rima Fayaz Nilofar NikghadamThe function of the double-skin facade with natural ventilation is based on the thermal performance and airflow of the cavity. Structural features of a naturally ventilated double-skin façade that affect its thermal performance and fluid dynamics include geometri MoreThe function of the double-skin facade with natural ventilation is based on the thermal performance and airflow of the cavity. Structural features of a naturally ventilated double-skin façade that affect its thermal performance and fluid dynamics include geometric features such as cavity dimensions, airflow path, air inlet, and outlet areas, shading devices material and their location in the cavity, and material properties that are optical and thermal characteristics of transparent skin. In this research, Fluent Software was used to simulate the computational fluid dynamics, and by sensitivity analysis, the effect of changes in structural properties on thermal performance was evaluated. For this aim, 144 simulation scenarios with cavity depths of 30, 60, 90, and 120 cm, inlet and outlet cross-sections of 0.2, 0.4, and 0.8 m2, louver shadings with 0, 30, 45, 60, and 90 degree angles located at one third distance close to the exterior wall of the façade, the model without shading, exterior glass with regular and low emission layer were investigated, and the following results were obtained:- Cavity Depth: It was observed that as the depth increases, the velocity of airflow in the cavity decreases. Changing the width of the hole changes the surface temperature of the inner glass up to a maximum of 0.80 ° C (up to 2%). As the depth of the cavity increases, the heat flux transmitted through the inner glass surface decreases in most cases (up to 6.5%).- Cross-section: As the cross-section increases, the air velocity in the cavity increases the temperature of the inner glass surface changes irregularly but, in most cases, decreases. In addition, the heat flux passing through the inner glass surface often increases (up to a maximum of 16.3%).- Shading: In the case without shading, the air velocity in the cavity is 0.30 to 0.70 m/s, and in the case with 45 degrees of shading, the air velocity in the cavity is between 0.30 and 0.92 m/s. In the case without shading, the temperature of the inner glass surface changes from 39.3 to 41.0 ° C, and in the case with 45 degrees, changes are between 38.65 to 39.5 ° C. In the case without shading, the heat flux transmitted through the inner glass surface changes from 78.0 to 120.0 W/m2, and in the case with 45 degrees shading, differences between 43.0 to 48.2 W/m2. The sensitivity of the heat flux transmitted through the inner glass surface to the presence or absence of shading can lead to a reduction of the heat flux transmittance through the inner glass surface by up to 61.0%.- Exterior glass type of DSF: In the case without shading, the reduction rate of heat flux from the inner glass surface is 19.44% to 29.78%, and in the case with 45-degree shading is from 17.71% to 24.44%. By changing the exterior glass's material (low emission or regular), the heat flux transmitted through the inner glass surface changes by 32.2 and 120 W/m2. Manuscript profile -
Open Access Article
3 - An intelligent adaptive skin from a biomimetic approach for energy consumption reduction
hossein mahyari Afsaneh Zarkesh Mohammadjavad MahdavinejadAbstractOne of the challenges facing human beings today is the excessive consumption of fossil fuels, which has led to the depletion of non-renewable energy sources and greenhouse gas emissions, as well as global warming and climate change. This challenge has led to the MoreAbstractOne of the challenges facing human beings today is the excessive consumption of fossil fuels, which has led to the depletion of non-renewable energy sources and greenhouse gas emissions, as well as global warming and climate change. This challenge has led to the search for solutions to reduce fossil fuel consumption, such as optimizing and reducing energy consumption and the use of renewable energy. One of the most important areas of energy consumption is man-made in the field of architecture. On the other hand, one of the most important parts of a building that interacts with the outside environment is its outer skin. In this study, the need to pay attention to the outer skin of the building, as one of the most important parts that can manage and control the amount of energy consumption in a building, has been addressed. Its purpose is to achieve appropriate and effective solutions to reduce energy consumption in the building by the adaptive skin. One of the sources of modeling is the study of the process of reaction of living organisms to their external conditions. In this research, general solutions to reduce building consumption in the field of outer skin as well as the convergence of challenges of a building skin and mechanisms in nature for survival are discussed. It can be said that one of the most similar living organisms to adapt behavior to the facade and skin of a building are plants. Because while they do not have much mobility, they have to manage their challenges such as receiving sunlight. By modeling plants, the challenges of using and protecting sunlight in the building can be managed. The method of collecting information and data from libraries and Internet sites and the research method is descriptive-analytical and simulation using simulation software and measuring its efficiency in controlling the entry of sunlight into the inside by climate analysis and light analysis software. By modeling the behavior of a special type of plant called Oxalis oregano and abstracting from it, a concept has been reached whose structural principles have been simulated by GrassHopper plugin in Rhino software 6. This module can be generalized on the facade and can control the amount of sunlight entering the building mass by opening and closing it. Transparent photovoltaic cells (TPV) are used in the body of the module, which in addition to providing energy for opening and closing the modules, does not impede visual vision. Examining the effect of the outer skin on the simulated space, it was found that these skins reduce the total heat load by 28%, reduce cooling load by 56% and the probability of glare from daylight by 23%. By modeling plants due to their static nature and adaptability to their surroundings, a mechanism in the building such as responsive skin can be achieved that control the impact of environmental variables such as sunlight into the building and thus provide visual comfort to residents in the glare of daylight reduced the use of building cooling energy. Manuscript profile -
Open Access Article
4 - A Comparative Study of Façade Samples in Residential Buildings of Tehran by Analytical Hierarchy Process (AHP)
Mohammad-Hosein Shirazian Seyed-Bagher Hosseini Saeid Norouzian-MalekiNowadays, there is a rapid growth in residential construction in Tehran. Part of the growth is related to providing housing for citizen and reconstruction of old urban fabrics. Yet many difficulties and barriers may arise in the future due to the relative paucity of tec MoreNowadays, there is a rapid growth in residential construction in Tehran. Part of the growth is related to providing housing for citizen and reconstruction of old urban fabrics. Yet many difficulties and barriers may arise in the future due to the relative paucity of technical standards. The façade skin is considered as one of the most effective ways in aesthetic elements of the urban landscape. The facade plays a vital role in the distinction between interior and exterior spaces. Additionally, it is one of the most vulnerable elements of structures, when they are subjected to earthquakes. Tehran is placed in the one of the world’s most active seismic belts and has sustained repeated considerabledamages due to high magnitude earthquake activitieshappening in some 150 year cycle. Already 182 years have passed since the last one in 1830. It is feared that a major earthquake in Tehran, a megalopolis of over 8 million inhabitants, situated on among active faults, could well lead to substantial loss of life at some 380,000 in the worst case scenario and considerable financial damages particularly due to rapid urbanization started in the 1950s.The main objective of this research is to determine the most appropriate facade system for residential buildings in Tehran. Two types of double-skin facades (twin wall or incorporated shuttering wall and lightweight 3D sandwich panel) and single-skin facades (insulating concrete form and fiber cement board facade) have been selected based on the available studies of facade systems. Data was gathered through Delphi technique.The Delphi technique is an approach used to gain consensus among a panel of experts. This is normally achieved through a series of rounds where information is fed back to panel members using questionnaires.Fourcriteria were selected in the research. Thesecriteria are as follows: earthquake resistance, cost and speed of performance, heat insulation and architectural aesthetics. Weights of them were analyzed by analytical hierarchy process (AHP) method and the systems are compared. An AHP hierarchy is a structured means of modeling the decision at hand. It consists of an overall goal, a group of options or alternatives for reaching the goal, and a group of factors or criteria that relate the alternatives to the goal.Sincepairwisecomparisons are the keystone of these decision-making processes, correctly quantifying them is the most decisivestep inmulti-criteria decision-making methods which use qualitative data. Pairwise comparisons are quantified by using a scale. Such a scale is an one–to-one mapping between the set of discrete linguistic choices available to the decision maker and a discrete set of numbers which indicate the importance, or weightof the previous linguistic choices.In the final step of the process, numerical priorities are calculated for each of the decision alternatives. These numbers represent the alternatives’ relative ability to attain the decision goal, so they allow a straightforward consideration of the various courses of action.Accordingly, lightweight 3D sandwich panel is suggested as the most appropriate for residential buildings in the earthquakeprone areas of Tehran. Manuscript profile -
Open Access Article
5 - Measuring The Quality of Natural Lighting in A Building with Double Skin Façade (DSF)
A. E. Manubawa LMF Purwanto A. Ardiyanto -
Open Access Article
6 - An Efficient Double Skin Façade for an Office Building in Shiraz City
Ramin movahed pour Maria Kord Jamshidi Mohammadjavad Mahdavinejad -
Open Access Article
7 - Organizational Learning and Knowledge Spillover in Innovation Networks: Agent-Based Approach (Extending SKIN Framework)
M. Mahmoudzadeh M. Alborzi S. Ghazinoori S. Khalili Shavarini -
Open Access Article
8 - The Study of the Beliefs among Literate Citizens in Ashtian City in terms of Urban Development
Mohammad Tahmasbi Ashtiani Ali Roshanaie -
Open Access Article
9 - Architecture Follows Nature(Biotechnology A smart approach to energy conservation in building skins)
saba kheradmand hassan satari sarbangholiSince 1970, a major problem worldwide is energy shortage along with the high consumption of energy in buildings. Architects are attempting to find solutions for managing buildings energy consumption. One innovative approach is Biomimicry. A subcategory of biomimicry is MoreSince 1970, a major problem worldwide is energy shortage along with the high consumption of energy in buildings. Architects are attempting to find solutions for managing buildings energy consumption. One innovative approach is Biomimicry. A subcategory of biomimicry is building skin which forms the entire exterior of the building. It is the boundary through which the buildings interaction with the environment occurs. Proper management of the building skin can significantly reduce the building's energy demand. The main objective of this paper is to investigate the ability of reducing energy consumption by applying the biomimicry approach on buildings skin design. In order To achieve this aim, a research methodology has been designed to accomplish four objectives. First, it will carry out an in depth research on biomimicry, skin, and biomimicry in building skin through the study of existing literature. Second, international case studies will be presented and analyzed in terms of usage of biomimicry, in addition to, the impact it had on reducing the buildings energy consumption. Finally it will conclude with guidelines for building skin biomimicry design for more efficient energy consumption in buildings. Manuscript profile -
Open Access Article
10 - Compare the effect red and green low level laser light accelerates the healing of the incision in the skin after the suturing in hamsters
GH. R. Abedi, احمد Asghari, S. Hesaraki, A. Nasireian, هادی Hajizadeh, نیما Toghani,Accelerated wound healing was the first application for this type of laser. In terms of green lightlaser ability which whether it can enhance wound healing or not there is some disagreement. thisstudy was done in order to compare the green and red light lasers (less pow MoreAccelerated wound healing was the first application for this type of laser. In terms of green lightlaser ability which whether it can enhance wound healing or not there is some disagreement. thisstudy was done in order to compare the green and red light lasers (less powered one) in terms ofaccelerated wound healing which can be done surgically on the skin. In this study thirty healthy,mature hamster from suyrian strain was selected and randomly divided into three different groupas below: A: control group, B: group which was under the radiation of low level red laser, C:group which was under the radiation of low level green laser. After the induction of generalanesthesia, the straight incision at the length of two cm was created in the dorsal zone of animal,then by means of nylon 5-0 was sutured in a simple manner. In the group A the cutted sitewithout any intervention was remained intact in order to proceed first type of wound healing, inthe group B (by red laser) and C (by means of green laser) the cutted site was treated with thevelocity of 0.5 J/cm2 during one minute by constant movement of lasers on the surface of incisionwhich was continued up to six days. Sampling was done in the 3th 7th, and 12th days. Theaverage wound healing in groups B and C were significantly higher than the control group, butbetween the two green and red laser, there was no meaningful difference. Although the red lasera little bit was good during operation compared with the green one. Less powered laseraccelerates the process of wound healing. In those situations which the case is resistance towound healing we can use less powered lasers. Manuscript profile -
Open Access Article
11 - Comparative study on geometric and histopathologic effects of polar, semi polar and non-polar fractions Artemisia absinthium extract in rat
Rezaei, A., Mohajeri, D., Ahmadizadeh, Ch., Jalilzadeh, M. .Recovery of Scars is a treatment challenge in some diseases and chronic disorders. For this reason, new compounds are used for rapid recovery of Scars and conglutination. It is expected that Artemisia absinthium as a galenical and herbal drug, has rapid recovery effects MoreRecovery of Scars is a treatment challenge in some diseases and chronic disorders. For this reason, new compounds are used for rapid recovery of Scars and conglutination. It is expected that Artemisia absinthium as a galenical and herbal drug, has rapid recovery effects in scars and sores because has anti- inflammation effects, activation of fibroblast cells and also antihyaluronidase effects cause the rapid recovery of sores. In this study, effects of Artemisia absinthium on recovery of sores as polar, semi polar and non-polar extractions of it are investigated on the rat as a second recovery. After anesthesia, with use of biopsy punch, Created circular sores with full thickness on the 70 female rats and recovery process were investigated in 5 groups. Drug administration and sores measures performed with analyzing of digital Scans, once a day for 21 days. For microscopic observations, gathered Samplings form this tissue in the 0, 3, 7, 14, 21 days, and microscopic symbols are ranged as edema factors and swelling reactions, hyperemia and bleeding, fibroblast, of Coverage tissue, torsion of sores and maturation of granular tissue. After histopathology and Calculation of recovery of sores scale for each drug, the finding results analyzed with SPSS software 17 versions. On the basis of geometric findings of recovery period, observed that semi polar extract of Artemisia absinthium has maximum Contraction of sores and control group has the least contraction of sores. Also, based on the histopathology results, total recovery in this group is better than other groups. In the second and third week. Recovered tissue has better organization than the other groups. Manuscript profile -
Open Access Article
12 - Study of effect of olive oil on re-epithelialization of epithelial tissue in excision wound healing model in rats
Abooei Mehrizi, M., Eidi A., Mortazavi, P. .Olive oil has been used for medical purposes. It has beneficial effects on cardiovascular and metabolic diseases, inflammatory and autoimmune diseases. The objective of this study was to find out the efficacy of topical administration of olive oil on dermal wound healin MoreOlive oil has been used for medical purposes. It has beneficial effects on cardiovascular and metabolic diseases, inflammatory and autoimmune diseases. The objective of this study was to find out the efficacy of topical administration of olive oil on dermal wound healing in rats. After creating full-thickness skin wounds on the back of 60 male Wistar rats, rats randomly divided into six groups, as control, sham, treatment and standard. Control group was intact. Sham group received eucerin as vehicle. Treated group received the olive oil at doses 2, 5 and 10%, dissolved in eucerin. Standard group were treated with phenytoin ointment 1%. Wound healing rats were calculated on days 3, 7, 11, 14, 18 and 21 post-wounding and the wound tissues were harvested at 3, 7, 14 and 21 days for histological studies. All of rats were sacrificed, and the skin around incision area was dissected and stained by Masson’s trichrome methods for tissue analysis. The results indicated a significant decrease in the diameter of wound in the treated and standard groups comparing to the control groups. A significant increase in the rate of re-epithelialization was observed at 14 days in the treated and standard groups compared to the control group. The results demonstrate that olive oil significantly accelerates cutaneous wound healing and its effect may be due to the increased re-epithelialization. It was concluded that it can be considered as a therapeutic agent for wound healing Manuscript profile -
Open Access Article
13 - Molecular identification of Staphylococcus aureus enterotoxin genes isolated from human skin tissue rashes and ewes milk with subacute mastitis
Kiani salmi, A., Ebrahimi Kahrizsangi, A., Mokhtari, A. .Staphylococcus aureus is a gram-positive coccal bacterium of the micro cocaceae family and by the release of toxins such as enterotoxins provides invasion to the host. The aim of this study was to identify enterotoxin genes of Sea, Seb, Sec and Sed in Staphylococcus aur MoreStaphylococcus aureus is a gram-positive coccal bacterium of the micro cocaceae family and by the release of toxins such as enterotoxins provides invasion to the host. The aim of this study was to identify enterotoxin genes of Sea, Seb, Sec and Sed in Staphylococcus aureus isolates of human skin infections and ewes with subacute mastitis. In this study 110 suspected S. Aureus isolates were collected from Chaharmahal and Bakhtiari province, the isolates were confirmed using microbiological standard methods. Then the PCR test was performed on 67 samples using specific primers to identify mentioned genes. The results showed that within 38 samples of human skin infections 19 cases were positive for Seb and Sea genes. 7 cases had Seb gene (18.42%). And 12 samples (31.58%).) were positive for Seagene. Within29 samples of ewe subacute mastitis 13 cases were positive for Sea, Seb, Sec and Sed genes. 5 samples had Sea gene (17.24%), 4 were positive for Seb (13.79%), 3 were positive for Sec (10.34%) and 1 had Sed gene (3.45%). Results were confirmed by sequencing and showed a high percentage of Staphylococcus aureus isolated from clinical specimens had enterotoxin genes. Given the importance of these toxins produced by pathogenic strains, if the expression of these genes occurs, early treatment of infection would be necessary. Manuscript profile -
Open Access Article
14 - Preparation of Low Calorie Sour Tea Jelly Using Stevia and Gelatin of Chicken Skin- Evaluation of the Product
F. Yazdani Z. Raftani Amiri H. Shahiri TabarestaniIntroduction: The aim of this study was to produce low-calorie jelly using sour tea as a natural coloring agent, gelatin extracted from chicken skin with stevia as sweetener. Materials and Methods: Chicken skin gelatin was extracted by using alkaline-acid pre-treatment MoreIntroduction: The aim of this study was to produce low-calorie jelly using sour tea as a natural coloring agent, gelatin extracted from chicken skin with stevia as sweetener. Materials and Methods: Chicken skin gelatin was extracted by using alkaline-acid pre-treatment with 1 N of NaOH and 0.05 N hydrochloric acid. Gelatin was used at the concentrations of one and two percent (wt.%), Stevia with 0 to 100% replacement rates with sugar and sour tea at 20 wt.% for 100 g of jelly and 48 hours after gel production, pH measurement, Brix, moisture content, acidity, water activity, tissue stiffness, color, sensory analysis and microbial tests were performed. Experiments were conducted in a completely randomized design based on factorial experiment using SPSS software and compared with Duncan's multiple range test at 5% probability level. Results: The results showed that by increasing gelatin concentration and the level of sucrose replacement with stevia did not have a significant effect on pH. By increasing the concentration of gelatin, texture hardness and L*, significantly increased and moisture decreased (p < 0.05), whereas the parameters of brix, water activity, a* and b* of samples were not significantly different (p> 0.05). By increasing the levels of sucrose replacement with stevia and decrease of solids content the moisture, water activity and L *, a *, b * factors were significantly increased and the brix of the samples decreased. Conclusion: Sensory and physicochemical properties of sour jelly samples showed that using chicken skin gelatin and stevia as sweetener could be a good alternative to low-calorie jelly formulation by preserving physical, chemical and sensory properties. Due to medicinal properties, sour tea provides beneficial contribution to sour jelly product Manuscript profile -
Open Access Article
15 - Sequential Solvent Extraction of Red-Onion (Allium cepa L) Skin: Influence of Solvent Polarity on Antioxidant and Radical Scavenging Activity
S. Mahdian Kouchaksarayi S.M. Vahdat M. Hejazi M. Khavarpour Z. Salimi -
Open Access Article
16 - Assessment of the Impacts of Increasing Cavity Depth and Floor Numbers on Energy Performance of Different Types of Double Skin Facade in Office Buildings of Cold Climate in 36 Different Scenarios (Case Study: An Office Building in Tabriz)
Shirin Nourivand Lida Balilan Lida Balilan Maziar AsefiBackground and Objective: As a result of the rising awareness of environmental issues and the increase in the cost of energy, building professionals increasingly have to consider the sustainability and energy performance of their designs by using building energy perform MoreBackground and Objective: As a result of the rising awareness of environmental issues and the increase in the cost of energy, building professionals increasingly have to consider the sustainability and energy performance of their designs by using building energy performance simulation tools. The aim of the current study is to optimize energy consumption of office buildings in cold climate of Tabriz and providing optimal model of double skin façade (DSF) in this climate.Material and Methodology: The research method in this paper is based on causal research and simulation. The research tool in this paper is Design Builder software. The energy performance of DSF is studied in 36 scenarios under 4 types of DSFs in an office building in cold climate of Tabriz in three cavity depths of 0/7, 1 and 1/3m in three modes: 5,10 and 15-story to achieve minimum energy consumption.Findings: The results indicate that, the 5-story box window type with a depth of 1/3m has a minimum electricity consumption and the 15-story multi-story type with a depth of 0/7m has a minimum gas consumption. In a fixed cavity depth, electricity consumption will increase and gas consumption will decrease by increasing the numbers of floors. Electricity consumption also increases with the increase of cavity depth. The 15-story multi-story DSF with a cavity depth of 1m has the lowest total energy consumption and the 5-story corridor DSF with a cavity depth of 0/7m has the highest total energy consumption.Discussion and Conclusion: Due to the high heating needs of the cold climate and energy efficiency of DSF facades, it is necessary to choose the appropriate type for this region. Manuscript profile -
Open Access Article
17 - The Effects of Inner and Outer layers of Double Glazed Facade on the Rate of Energy Consumption in Official and Educational Buildings (Case study: Iran University of Science and Technology)
Fatemeh MehdizadehSeraj Mohammad Mehdi Danesh Haniyeh SanaeiyanIntroduction: The presence of computers and working equipments in official and educational buildings caused the increasing of internal temperature and using glass façade vastly has caused more negative effects of this problem. The question is how to reach to the MoreIntroduction: The presence of computers and working equipments in official and educational buildings caused the increasing of internal temperature and using glass façade vastly has caused more negative effects of this problem. The question is how to reach to the comfort degree of internal temperature without using excessive energy at the same time of benefitting the visual beauty of the glass façade. The aim of this study is to evaluate the effects of the quantity of layers of the internal and external of double skin façade on energy consumption. Methods of study: The method of this research is based on causal modeling and simulation. The used equipment was the software of thermostatic simulator called “Design Builder”. In order to reach to the lowest level of energy consumption, different modes of the layers in the double skin façade were analyzed by using the design builder software. Findings: The results revealed that in double skin facades, changes in the number of inner layer are efficient in reducing energy consumption, while the outer layer of glazing does not play any role. Using the double skin facade in southern side is more effective because of the sun radiation on this side. Results: Due to the heating and cooling degree days in Tehran which is equal to 1610 and 1435°C respectively, in the summer, habitability and comfort level of residents were demanded mostly. So in the summer, change in the number of inner layers is more effective than the outer layer. Manuscript profile -
Open Access Article
18 - Analyzing the double skin facade moving in the efficiency of energy consumption in residential buildings sustainability in Tabriz city
Seyed Mehdi Ghoddosifar Mahsa Faramarzi AslBackground and Objective: Double skin facades (DSF) are an interesting and important architectural element in buildings because they are very visually appealing and at the same time can perform better than single skin facades. Double skin facades must be properly MoreBackground and Objective: Double skin facades (DSF) are an interesting and important architectural element in buildings because they are very visually appealing and at the same time can perform better than single skin facades. Double skin facades must be properly designed and implemented, otherwise their potential benefits may be lost. For this reason, the physical processes occurring in a double skin facade must be well understood and predicted. However, they are very dynamic and static. The aim of the current research is to analyze the double skin facade moving in the efficiency of energy consumption in residential buildings in Tabriz city. Material and Methodology: In this research, the analytical descriptive method as well as numerical equations, Design Builder software, Converge and sensitivity analysis were used. Findings: The results showed that for the double skinned facade in cold seasons, by blocking the top and bottom of the double skinned facade, the air trapped between the double skinned facades is functional insulation and energy loss is reduced. Also, in hot seasons, by leaving the top and bottom of the skin open and creating air flow between the double skin, the heat transfer from the building increases and as a result, the temperature inside it decreases. Discussion and Conclusion: The results of numerical solution of computational fluid dynamics equations in Design Builder software showed that using this method in Tabriz city, the annual cooling load is reduced by 45% and the annual heating load is reduced by 5%. Manuscript profile -
Open Access Article
19 - Moses’ Mīqāt in Quran
Musa Modabber Poor Mahdi Moti’ Mohammad Reza Haji IsmaeliOccasion of approaching Lord is called “Miqat” for gnostic. Moses’ Miqat in Aa’raaf Surah in two forms: “structural: a report on basic Miqat in 30 nights and additional in ten nights” in Verse No. 142 of Aa’raaf Surah and the co MoreOccasion of approaching Lord is called “Miqat” for gnostic. Moses’ Miqat in Aa’raaf Surah in two forms: “structural: a report on basic Miqat in 30 nights and additional in ten nights” in Verse No. 142 of Aa’raaf Surah and the content stage of the report: “asking for Meeting Allah by Moses and Lord’s reply” in Verse No. 143 of mentioned Surah. Three viewpoints are discussed in this regard: 1- asking for meeting Lord by physical eyes on behalf of his tribe. 2- asking for meeting Lord by physical eye for himself. 3- asking for intuitive meeting with no agent for himself; according to his Prophetical dignity and Quranic witness such as “thunderbolt” as Divine doom, he had never asked for meet Lord intuitively and on behalf of his tribe. Based on his insufficient capability for meeting Lord, Allah manifested on a mountain with no agent and Moses got mad and fainted. Manuscript profile -
Open Access Article
20 - Molecular detection of DHA beta-lactamase gene in Pseudomonas aeruginosa isolated from skin samples in Qom
Horisadat Hejazi Mohsen Zargar mehrdad mamarianIntroduction Pseudomonas aeruginosa can infect virtually all tissues in the body. this bacteria can be colonized in burns, wounds, corneal tissue, urinary tract and lungs, and after entering blood, cause septicemia or localized lesions in other parts of the body. Today, MoreIntroduction Pseudomonas aeruginosa can infect virtually all tissues in the body. this bacteria can be colonized in burns, wounds, corneal tissue, urinary tract and lungs, and after entering blood, cause septicemia or localized lesions in other parts of the body. Today, due to the untapped use of effective drugs On the pseudomonas aeruginosa, this bacterium is strongly resistant to antibiotics. The purpose of this study was to find the gene for resistance to beta-lactams in pseudomonas aeruginosa isolated from skin samples. materials and methods: A total of 100 isolates of Pseudomonas were used in Microbiology Bank of Microbiology Research Laboratory of Islamic Azad University of Qom. After cultivation and biochemical confirmation of isolates, genomic extraction was performed first to detect these genes and then detected by PCR with DHA genes. Results: 45 isolates resistant to imipenem; 22 cases were positive in the double-synergistic disks. Six isolates were positive for DHA gene. Conclusion: Increasing resistance to Pseudomonas aeruginosa causes problems in treating patients and a periodic review of drug allergy for inappropriate treatment. Manuscript profile -
Open Access Article
21 - Using a phenotypic method to confirm the presence of the efflux pump associated with resistance to ciprofloxacin in Pseudomonas aeruginosa isolated from skin samples
Ali Rahmati Mohammad Reza zolfagharyIntroduction One of the most important causes of nosocomial infections in patients with skin infections is Pseudomonas aeruginosa. The occurrence of antibiotic resistance with various mechanisms is one of the problems in treating these patients. The main role in the de MoreIntroduction One of the most important causes of nosocomial infections in patients with skin infections is Pseudomonas aeruginosa. The occurrence of antibiotic resistance with various mechanisms is one of the problems in treating these patients. The main role in the development of multiple resistance to antimicrobial drugs is played by the MexAB efflux pumps. The aim of this study was to evaluate the presence of the MexAB efflux pumps in the Pseudomonas aeruginosa isolated from skin samples. Materials and Methods: In this study 200 swab specimens from patients with skin infections were collected in Qom hospitals. Pseudomonas aeruginosa specimens were confirmed by biochemical tests. The drug susceptibility pattern was compared to ciprofloxacin by disk diffusion method and the phenotypic study of the effects of efflux pumps was done using cartwheel method . Results: In this study, 89 (45%) samples were infected with Pseudomonas aeruginosa, of which 19 cases (21%) were resistant to ciprofloxacin and more than 54% of the presence of the pump in the Pseudomonas aeruginosa more than 54% of the presence of the pump in the Pseudomonas aeruginosa. Conclusion: the presence of more than 54% of the presence of the pump in the Pseudomonas aeruginosa, is important in order to suggest a suitable therapeutic model for the infected patients. Keywords: Pseudomonas aeruginosa, skin infections, efflux pump Manuscript profile -
Open Access Article
22 - A comparative study of the effects of hydroalcoholic extracts of purslane (Portulaca oleracea L.) and henna leaves (Lawsonia inermis L.) on wound healing in male Wistar rats
Fatemeh JamallouObjectives: One of the medicinal plants known in traditional medicine, henna with the scientific name Lawsonia inermis L. comes from the Lythraceae family and purslane with the scientific name Portulaca oleracea L. comes from the Portulacaceae family. According to the c MoreObjectives: One of the medicinal plants known in traditional medicine, henna with the scientific name Lawsonia inermis L. comes from the Lythraceae family and purslane with the scientific name Portulaca oleracea L. comes from the Portulacaceae family. According to the compounds present in these plants, many properties such as antimicrobial, anti-inflammatory, wound healing, trypsin inhibitory and antioxidant properties have been reported for them.Materials and Methods: This study was conducted on 24 male rats in the weight range of 200±20 grams, which were divided into 4 groups of six. Wounds 2 cm long were created on the back skin of mice: the first group was kept without treatment as a control, the second group was treated with Esrin (negative control) and the other two groups were treated with ointments made of henna and purslane with a concentration of 50% by weight. -Weight was used in the daily basis of Esrin. The area of the wound was measured daily from the second to the fourteenth day with Autocade software. The data were analyzed using SPSS software at a significance level of p<0.05.Findings: The decrease in wound area was significantly higher in all groups treated with purslane and henna. Purslane showed a better effect.Conclusion: Henna and purslane ointment can be used as effective substances in the treatment of skin wounds by significantly reducing the healing time and wound area. Manuscript profile -
Open Access Article
23 - The Objectives of the Formation of Traditionalism in the Intellectual System of Nasr
seyedsajjad aleseyedghafour masoud moeinipourThe subject of this article is the objective context of the thought of Seyed Hossein Nasr. (Problem) It is therefore important that the traditionalist discourse, along with two fundamentalist and modernist discourses of Islam, has many thinkers and critics. Various meth MoreThe subject of this article is the objective context of the thought of Seyed Hossein Nasr. (Problem) It is therefore important that the traditionalist discourse, along with two fundamentalist and modernist discourses of Islam, has many thinkers and critics. Various methods can be used to study the thoughts of thinkers. In this research, we tried to use the skinner's hermeneutic method to explain the objective fields of Nasr's political thought. First, Skinner's method and its main concepts are explained, which emphasizes the two elements of intention and context. It has also been attempted to draw a perspective on the possibilities of the above methodology for analyzing political thought. Then he explains the life of Nasr as the subject of his thinking. The objective fields of thought of Seyyed Hossein Nasr mean the study of biography and biography of a person from the beginning of life to the attainment of intellectual maturity, and then to better understand how the formation of thoughts and ideas of the author in the context of history, how education in social relations in The opinions of one person are influenced and then they examine the intellectual and political environment of the author, which allows him to understand his work better. (Findings) Manuscript profile -
Open Access Article
24 - Humorous Article on Bahram Sadeghi s Work Based on Robert Delios Theory With Emphasis on (Empty Trench and Thermoses and Heaven)
Fereshte Moradi Navazollah Farhadi Mohammad ShafieiRobert Lillo's Theory of Linguistic Comedy is one of the complete linguistic theories of humor that was first put forward by Robert Raskin under the concept of "semantic paradigm" by Viktor Raskin. It is distinct and distinct from the non-linguistic one, and this is the MoreRobert Lillo's Theory of Linguistic Comedy is one of the complete linguistic theories of humor that was first put forward by Robert Raskin under the concept of "semantic paradigm" by Viktor Raskin. It is distinct and distinct from the non-linguistic one, and this is the only ambiguity that lends humor to the linguistic feature; these ambiguities occur in three phonetic, lexical, syntactic, and cognitive applications. BahramSadeghi also used linguistic paradigms to humorize his anecdotes. The results of this research, obtained by the descriptive-analytical method, show that Robert Lieu's semantic theory of theory and its theoretical framework are largely consistent with Bahram Sadeghi's satirical works.The results of this research, obtained by the descriptive-analytical method, show that Robert Lieu's semantic theory of theory and its theoretical framework are largely consistent with Bahram Sadeghi'ssatiricalworks. Manuscript profile -
Open Access Article
25 - Removal of C.I. Acid red 1 (AR1) dye pollutant from contaminated waters by adsorption method using sunflower seed shells and pine cone as agro waste materials
Samira Alizadeh Kambiz Seyyedi -
Open Access Article
26 - Effects Of Formalin and Copper Sulfate on Skin Tissues Of Khazar White Fish (Rutilus kutum
Massoud Farokhroz Abbas Ali Zamini Elahe MozafariInroduction and Objective: Formalinand copper sulfate are compoundsthanthosewho areconstantly inaquacultureto treatparasitic infectionsandbacterialinfectionsareused. Fishskinare as organsthatareconstantlyexposed tothe external environmentandbecause ofits roleinrespira MoreInroduction and Objective: Formalinand copper sulfate are compoundsthanthosewho areconstantly inaquacultureto treatparasitic infectionsandbacterialinfectionsareused. Fishskinare as organsthatareconstantlyexposed tothe external environmentandbecause ofits roleinrespirationandosmoticbalance ofthese chemicalsandheavy metalare thefirst target. The purpose ofthisstudyis ofhistopathologicaleffectsof copper sulfateandformaldehydeconcentrationsonskintissue ofwhite fishin the Caspian SeaMaterial and Methods: In this research, indication of probable waste for skin tissues of Khazar white fish with average weight of 428 Mg and length weight of 3.5 Cm is addressed after exposing to different compactness of copper sulfate (in 20 minutes short time care and 24 hours long time care,100ppm and 1ppm) and formalin (in short time care and long time care,25ppm and 250ppm). After stabilizing tissues in 10 percent formalin and making 5 micrometer section, it is painted with hematoxylin method and is studied by optical microscope.Results:The results showed that in the consideration of skin histology, there was not any changes in skin cells which was in exposure of lowest compactness of copper, but in compactness of 100ppm disparting epidermis layers was more than basal layer. Keratinocyte layer existent in skin remained without any change and effects of bleeding was not seen.Conclusions:In considerations of skin, individuation of layers is seen in a mild extent and in long time care is seen in Malpigy cells and disparting epidermis layers from basal layers and effects of hyperemia has not been seen. Manuscript profile -
Open Access Article
27 - Effect Of Saccharomyces cerevisiae AT-50 Cell Wall on Growth Of Isolated Coagulase-Positive Cocci from Normal Skin Toe in Diabetics
Azadeh Tofighi Asadirad Mohammad Hosein ArashIntroduction and Objectiv:Diabetes Mellitus is one of the most common endocrine diseases and currently affects 382 million people. One of the problems with diabetes causes skin ulcers leading to amputation. Balancing the indigenous skin micro flora and reducing skin opp MoreIntroduction and Objectiv:Diabetes Mellitus is one of the most common endocrine diseases and currently affects 382 million people. One of the problems with diabetes causes skin ulcers leading to amputation. Balancing the indigenous skin micro flora and reducing skin opportunistic pathogen play an effective role on preventing or reducing skin scars. Prebiotics are used in various industries to increase the resistance against disease and health promotion. The objective is to study the prebiotic effect of Saccharomyces cerevisiae AT-50 cell wall to inhibit the growth of gram+ive, catalase+ive cocci isolated from normal skin between the toes in diabetics. It aims to design a method for prevention of diabetic ulcers.Material andMethods:Healthy skin between the toes in 53 diabetic patients and 50 non- diabetic patients were sampled.Gram +ive, catalase -ive strains were isolated. Saccharomyces cerevisiae AT-50 cell wall prepared by sonicator, followed by evaluating prebiotic effect of 1.5 and 3 percent of the pure cell wall on coagulase +ive isolates using well method. The inhibition zone diameter were measured in millimeters and compared as inhibitory effects.Results:The results showed that the total count ratio of anaerobic and aerobic isolates from diabetic and non diabetic samples was 1.44 and 1.24, and the total count ratio of aerobic and anaerobic isolates from diabetic samples were 1.55 and 1.81, respectively.Also, the number of coagulase +ive gram +ive cocci isolated from skin samples from diabetes, was 75 % more than the control sample.Conclusion:The skin of people with diabetes, regardless of age and sex to non- diabetic healthy skin had more favorable conditions for microbial growth, especially for coagulase +ive cocci. Inhibitory effect of prebiotic Saccharomyces cerevisiae AT-50 cell wall was related to dosage. Inherent resistance was seen in diabetic patients. These results can be used in the future as a model for the prevention, reduction and control of chronic wounds such as diabetic ulcers. Manuscript profile -
Open Access Article
28 - Collagen Turnover in Healing of Cutaneous Wounds by Aloe vera Fresh Gel in Mouse: Involvement of Fibroblast Growth Factor Receptor
Mehran Arabi homeira JafarzadehInroduction & Objective: Using herbal products like Aloe vera (Aloe barbadensis Miller) plays an important role in wound healing. This study aimed to evalutea the curative influence of Aloe vera (AV) fresh gel on healing of open cutaneous wounds in mouse. Material MoreInroduction & Objective: Using herbal products like Aloe vera (Aloe barbadensis Miller) plays an important role in wound healing. This study aimed to evalutea the curative influence of Aloe vera (AV) fresh gel on healing of open cutaneous wounds in mouse. Material and Method: Mice were 1) pseudo-control (sham): wound treated with physiological serum; 2) wound treated with 2 gr AV fresh gel. Two equal full-thickness skin wounds were made on vertebral column in the sacral region. On 8th and 16th post wounding day, skin sampling for the purpose of gene expression of fibroblast growth factor receptor (FGF-R) under RT-PCR evaluation was taken place. Urine samples were used to determine the concentration of hydroxy proline (HP) as a marker of collagen turnover in wounds, using HP assay kit. Results: AV fresh gel could up-regulate the expression of FGF-R gene as compared to negative and pseudo-controls (P<0.05). In addition, HP concentration was incresed in AV gel-treated groups comparing to others. Conclusion: We revealed that AV fresh gel was capable of healing wounds via elevation in collagen turnover and represents a good candidate for a wound healing process in human and animals. Manuscript profile -
Open Access Article
29 - Application of shrimp skin waste in green synthesis of polymer nanocomposite containing iron oxide nanoparticles to remove chemical toxins from water sources
Roya Behrooz Dadkhoda Ghazanfari nahid Rastakhiz Enayatollah Sheikhhosseini Sayed Ali AhmadiThe increase in the production of food waste and their entry into the environment through urban waste has created many problems for biological resources. Therefore, it is very important to present new methods in the elimination and optimal use of food waste. Preparation MoreThe increase in the production of food waste and their entry into the environment through urban waste has created many problems for biological resources. Therefore, it is very important to present new methods in the elimination and optimal use of food waste. Preparation of polymer nanocomposites from food waste is one of the methods of optimal use of these materials. In this research work, chitosan polymer nanocomposite containing iron oxide nanoparticles was prepared using shrimp skin waste and pistachio green skin extract. Also, the effectiveness of this composite as a filter in removing malathion poison from water sources was investigated in different conditions of poison concentration, amount of adsorbent and pH. The results of examining the morphology and surface characteristics of the prepared nanocomposite using electron microscope images show that the average diameter of nanofibers in this structure is about 40 nm. Also, the presence of iron oxide nanometer particles with an average size of 47 nm can be seen in the structure. Also, the results of absorption test by nano adsorbent showed that the maximum amount of absorption of malathion poison is 90% at pH=7 and with 0.7 grams of adsorbent. Manuscript profile -
Open Access Article
30 - Soure orange skin as an Adsorption for Azo dyes removal from aqueous media
Parya Nasehi -
Open Access Article
31 - The effect of volume fraction and size of Al2O3 nanoparticle on heat transfer and flow characteristics in the heat exchanger with louvered strip inserts
Meysam Pouyanian Ashkan GhafouriIn this study, the effect of using louvered strip inserts in heat exchangers on flow and transfer characteristics is numerically investigated. The continuity, momentum, and energy equations have been solved using a finite volume method. The wall of the tube is heated wi MoreIn this study, the effect of using louvered strip inserts in heat exchangers on flow and transfer characteristics is numerically investigated. The continuity, momentum, and energy equations have been solved using a finite volume method. The wall of the tube is heated with a uniform heat flux boundary condition. This paper uses a louvered strip insert arrangement (forward) with a Reynolds number of 10,000. The effects of louvered strip slant angle of and pitch of 50 mm were used for Al2O3 nanoparticles with different volume fractions in the range of 1% to 4% and different nanoparticle diameters in the range of 20 nm to 50 nm, mixed in a base fluid (water) is used. The comparison of numerical analysis results with existing equations has shown a good convergence. The numerical results reveal that the Nusselt number has increased with decreasing the nanoparticle diameter. The results indicate a slight change in the skin friction coefficient when nanoparticle diameters of Al2O3 nanofluid are varied. The Nusselt number increases with increasing nanoparticle volume fraction of Al2O3 /water nanofluid, while it is found that pure water has the lowest Nusselt number value. Also, the nanofluid has reduced the wall's temperature more than the base fluids (water), which indicates the advantage of using nanofluids in improving the system's thermal performance. Manuscript profile -
Open Access Article
32 - Examination of the components of Sayyid Qutb's political approach in Tafsir Fi-Zalal-e-Qur'an; based on Skinner's intentional hermeneutic method
leda madade hosain khoshdel mofrad mohamad nasehiAbstract:The political orientation to the interpretation of the Holy Quran has been one of the interpretation methods and one of the innovations of the commentators of the Holy Quran in recent centuries. According to this trend, the commentators seek to find answers to MoreAbstract:The political orientation to the interpretation of the Holy Quran has been one of the interpretation methods and one of the innovations of the commentators of the Holy Quran in recent centuries. According to this trend, the commentators seek to find answers to the political issues of the societies and seek the solution to the problems and problems from the Holy Quran. Sayyid Qutb's comments regarding political issues in this interpretation are facing challenges, the nature of which is the problem of this article. The method of collecting information in this research is library and documentary and with descriptive and analytical methods. has been placed. In order to achieve this purpose, using Quentin Skinner's hermeneutic intentionalist methodological model, the understanding and decoding of the hidden meaning behind Seyyed Qutb's opinions was discussed. Based on the findings and results of the article, the dual linguistic and intellectual fields such as the influence of the political family, the internal crises of the Islamic world, joining the Muslim Brotherhood, the intellectual influence of the Al-Manar movement, the influence of the contemporary Salafi movement and imprisonment on the one hand, and practical and environmental contexts such as governance Religion, Jahili society, influence on radical groups, instrumental view of religion, strong stance on people of the book and strict criticism of western civilization on the other hand, caused Seyyid Qutb to adopt the method of political interpretation Manuscript profile -
Open Access Article
33 - Systematic Review of Wound Dressings: A Movement from the Past to the Present
Pouriya Norooz Kermanshahi Graça SoaresThis systematic review aims at investigating different wound dressings commonly used for the healing process and skin repair. Five databases, namely SCOPUS, Web of Science, Medline, Google Scholar, and Cochrane Database of Systematic Reviews, up to 2020, were scanned fo MoreThis systematic review aims at investigating different wound dressings commonly used for the healing process and skin repair. Five databases, namely SCOPUS, Web of Science, Medline, Google Scholar, and Cochrane Database of Systematic Reviews, up to 2020, were scanned for papers specific to the topic of concern. The blinded randomized controlled trials, in vivo and in vitro studies comparing common wound dressings, including traditional, natural/biological, and artificial ones were studied in the present review. Finally, the researchers selected 22 studies. From which the data related to the clinical features of wound dressings and their advantages and disadvantages) were derived. The review of literature suggests that many treatment combinations are utilized as wound dressings based on the wound type and hospital guidelines. Nevertheless, there are conflicting views about the most appropriate choice. The findings of the reviewed articles indicate that hydrogels are the most common wound dressing used for wounds and burns due to high thermal/mechanical stability and low water evaporation. However, it is suggested to apply hybrid hydrogel membranes to overcome the low mechanical strength of a single component Manuscript profile -
Open Access Article
34 - Artificial intelligence in cancer diagnosis and treatment methods
javad safaei kuchaksaraei -
Open Access Article
35 - Face Detection with methods based on color by using Artificial Neural Network
Reza Abbasgolizadeh Habib Izadkhah Ramin Meshkabadi -
Open Access Article
36 - Thermal Behavior of Double Skin Facade in Terms of Energy Consumption in the Climate of North of Iran-Rasht
Narges Rezazadeh Hossein Medi -
Open Access Article
37 - surveying and ranking the effective factors on risk taking Entrepreneurs involved in home-based businesses with an emphasis on educating and training the risk taking managers
ebrahim halajeanThe research is concentrated on surveying and ranking the impacts of main factors and elements on entrepreneurs’ risking in urban and rural areas. In process of a descriptive – survery method , data is gathered by questionniare with 35 statements based on th MoreThe research is concentrated on surveying and ranking the impacts of main factors and elements on entrepreneurs’ risking in urban and rural areas. In process of a descriptive – survery method , data is gathered by questionniare with 35 statements based on the “Likert” 5 scales that its validity was sufficient, and the Cronbach's alpha reliability was 816. The research population were the entepreneurs in Mazandaran Province who introduced to receive bank facilities under the protection of Technical &Vocational Education Organization.128 ones as the sample were selected among 200 population according to Kerjesi & Morgan method to perform the reseach questionnaire. The agents and factors have been surveyed,analyzed and stated by Mean Index (X) and T –test , SPSS & EXCELL software model.Results show that the effecting factors that naturally cotain cultural , political, economical, social, training – psychological, managerial – administrative and geometrical have been accepted, emphasized and generalized in eight hypotheses.AS a conclusion the effects of seven factors have been generalized in entreprenueres’ society of home business field. Due to Fridman Test the cultural factor known as having the most effect while the managerial-administrative and geometrical factors have the low impacts. Manuscript profile -
Open Access Article
38 - Machine scheduling for multitask machining
Saleh Yavari Ahmed Azab Mohammed Fazle Baki Mikel Alcelay Justin Britt -
Open Access Article
39 - Effect of extraction time on properties of gelatin from the skin of crucian carp (Carassius carassius)
H. Faghani LangroudiAbstract[1]Crucian carp (Carassius carassius) skin was used for production of gelatin. The gel strength of gelatins extracted for 1, 3 and 6 h was between 106-110 g (P>0.05). Glycine (349.21-350.29 residues/ 1000 residues), alanine (131.15-132.73 residues/ 1000 resid MoreAbstract[1]Crucian carp (Carassius carassius) skin was used for production of gelatin. The gel strength of gelatins extracted for 1, 3 and 6 h was between 106-110 g (P>0.05). Glycine (349.21-350.29 residues/ 1000 residues), alanine (131.15-132.73 residues/ 1000 residues), glutamine (81.76-82.57 residues/ 1000 residues) and proline (89.95-96.48 residues/ 1000 residues) were the main amino acids found in gelatins. Extraction time did not change the amino acid composition of gelatin for most of the amino acids; however the content of proline decreased with increasing extraction time. Gelatin extracted for 3 h had different color compared to other gelatins (P<0.05).Secondary structure of gelatin was influenced by extraction time. AIII/A1450 ratio of extracted gelatins was between 0.85-0.86 which confirmed the loss of triple helix in gelatin. Fourier transform infrared (FTIR) spectroscopy indicated that gelatin extracted for 6 h had significantly higher Δν(νI - νII) (114 cm-1) (114) indicating higher denaturation of α-helix chain. Crusian carp skin could serve as a valuable source for production of gelatin. * Corresponding Authors; Email: hamid.faghani@toniau.ac.ir Manuscript profile -
Open Access Article
40 - Production of functional beverage of grape juice and lemon skin distilment contained Bacillus coagulans
Z.S. Jaddi A. Ahmadi-Dastgerdi R. Sharafati-ChaloshtoriNowadays consumers' interest in processed foods such as probiotic beverages is increasing. Therefore, the purpose of this study was to produce a beverage made from sour grape juice and sour lemon peel containing Bacillus coagulans. In this experimental study, grape juic MoreNowadays consumers' interest in processed foods such as probiotic beverages is increasing. Therefore, the purpose of this study was to produce a beverage made from sour grape juice and sour lemon peel containing Bacillus coagulans. In this experimental study, grape juice and sour lemon peel were prepared. Treatments containing 12 (treatment 1) and 9 (treatment 2) percent grape juice plus 25% lemon peel sweat and 107 CFU/ml of Bacillus coagulans were prepared. The results showed that the acidity decreased during storage and the pH decreased. Brix and alcohol also had a steady trend. Phenolic compounds and antioxidant properties were higher in samples containing 12% grape juice than in samples containing 9% juice (p < 0.05). During the storage period, the amount of phenolic compounds decreased. The antioxidant property also decreased with time, with the effect of treatment 1 from 153.4 to 97.72 mmol Fe+2/g and in treatment 2 from 123.35 to 80.52 mmol Fe+ 2/g. The results showed that after 90 days, the treated beverages were free of microbial contamination (Coliforms, Escherichia coli, mold and yeast). The bacillus coagulans count was not less than 107 CFU/ml. Sensory results showed that the overall acceptance of treatment 1 was more than treatment 2 but there was no significant difference between the two groups. According to the results, our best treatment was 12% grape juice with 25% lemon sour skin and 107 CFU/ml Bacillus coagulans. Manuscript profile -
Open Access Article
41 - Evaluation of clinical efficacy of homologous Lumpy Skin Disease vaccine against challenge with Iran's circulating virus
Amir Javadi Samad Lotfollahzadeh Gholamreza Abdollahpour Arash Ghalyanchilangeroudi Sirous Sadeghian ChaleshtoriLumpy skin disease is a viral disease of cattle and buffaloes which causes skin nodules in susceptible animals. Implementation of mass vaccination is the most effective way for LSD control in endemic countries. LSD vaccine that was used in the current study is a domesti MoreLumpy skin disease is a viral disease of cattle and buffaloes which causes skin nodules in susceptible animals. Implementation of mass vaccination is the most effective way for LSD control in endemic countries. LSD vaccine that was used in the current study is a domestically produced vaccine containing live attenuated Neethling strain. In this clinical trial, 11 male calves aged 6 to 9 months with an approximate weight of 150 to 250 kg and without antibodies against LSDV were used. The calves were divided into three groups: the first group consisted of two animals that were injected with ten times the vaccine dose, the second group comprised of four calves that were injected with one dose of vaccine and the third group consisted of five calves that received the vaccine diluent and assigned as control. On the 21st day after vaccination, the calves were challenged with a pathogenic strain of LSD virus through simultaneous intravenous and intradermal inoculation. All 11 calves were examined clinically daily for 14 days after the challenge and all clinical signs were recorded. None of the vaccinated animals (ten times the dose and one dose) showed any clinical signs of LSD including cutaneous nodules and fever within 14 days after challenge, while all the animals in the control group (non-vaccinated) showed clinical signs of LSD including cutaneous nodules. Therefore, the vaccine used in the present study was effective in protecting against wild LSD virus. Manuscript profile -
Open Access Article
42 - Microscopic study of differentiation of the facial skin in Ghezel sheep
سید سجاد Hejazi ایرج Pousty مسعود Taghizadeh حسین Limouii The aim of this Study is determination of histogenesis of the facial skin in ghezel sheep. The study was in the form of descriptive observation conducted on 100 male sheep fetuses which were collected randomly from pregnant ewes at Tabriz abbatoine. T More The aim of this Study is determination of histogenesis of the facial skin in ghezel sheep. The study was in the form of descriptive observation conducted on 100 male sheep fetuses which were collected randomly from pregnant ewes at Tabriz abbatoine. The length of the collected fetuses were measured and their age calculated by the formula X= 2.1(Y+17) to be between 40 to 130 days old. Following fixation of the fetuses in 10% buffered formalin samples were separated from the face region having individual and tactile hair follicles. They were studied histologically after the histotechnique and H&E staining procedures. In initial stages of facial skin development, the epidermal layer consisted of a row of cuboidal cells (basal layer) covered by a row of squamus cells, the periderm. At the 8th week of gestation the intermediate layer was formed by multiplication of germinal layer cells which was converted to spinosus cell layer at the 14th week of gestation. The skin was cornified at the last trimester of gestation. Formation of hair follicles, sebaceous and sweat glands began at the 9th week of gestation. Sebaceous and sweat glands formed from primary hair follicles and the appearance of myoepithelial cells coincides with the formation of sweet glands. Unlike other mammals in which hair follicle grows obliquely, vertical growth of hair follicle was observed in sheep. It was concluded that the 13th week of gestation is a critical period in the appearance of most ovine fetal akin structures as mellanocytes, myoepithelial cells, sebaceous and sweet glands appear at this time. Based on the results of the present study, the developmental pattern of sheep embryonic skin is similar to that observed in man and other mammals. Manuscript profile -
Open Access Article
43 - Evaluation of wound healing activity of Echinophora platyloba extract on experimental full thickness skin wound in the rat
ahmad asghari maryam Kardooni There are some specific plants used in traditional medicine, one of which is Echinophora platyloba. This study was conducted to evaluate the effects of platyloba (Echinophora platyloba) on the experimental full-thickness wound healing in rats. In this study More There are some specific plants used in traditional medicine, one of which is Echinophora platyloba. This study was conducted to evaluate the effects of platyloba (Echinophora platyloba) on the experimental full-thickness wound healing in rats. In this study 80 adult male Wistar rats were used. They were randomly divided into four groups including control, placebo, therapeutic ointment 1.5% and 3%. Animals were anesthetized and scrubbed from the shoulder to the ilium. Then, a circular wound was made with a diameter of 15 mm on the back between scapula and ischial tuberosity. The control group received no medication, while the placebo group received eucerin, the third and fourth groups received 1.5 and 3% Echinophora platyloba ointment locally. Histological samples were taken on days 3, 7, 14 and 21 in each group, then all samples were sent to the laboratory and processed with H&E staining method. Histopathological evaluations showed better healing results in those groups which had received Echinophora platyloba extract in comparison to other groups. Moreover, wound healing was significantly better in these groups (p<0.05). In conclusion, the results obtained from this study indicate that Echinophora platyloba extract had positive effect on wound healing in rat. Manuscript profile -
Open Access Article
44 - Investigation of skin toxicity in breast cancer patients undergoing radiation therapy
Mohammad Bayatzadeh Sharifeh Shahi -
Open Access Article
45 - Analysis of Love in Lyrical and Epic Literature based on Ferdowsi Shahnameh and Rostavoli Knight in the Panther Skin
Ayda Hayatimehr Fereydoun TahmasbiThe manifestation of love in epic works has caused an inseparable and pleasant connection between epic and Lyric. Ferdowsi's Shahnameh and Rustavi's Leopard Cloth are among the works in which epic and richness are intertwined. "Love" has a high place in these two works. MoreThe manifestation of love in epic works has caused an inseparable and pleasant connection between epic and Lyric. Ferdowsi's Shahnameh and Rustavi's Leopard Cloth are among the works in which epic and richness are intertwined. "Love" has a high place in these two works. In the Knight In The Panther Skin , love and romance topics have a high frequency and the story revolves around love and epic. In such a way that sometimes the story begins with love, or continues with love, or ends with love. In Shahnameh, there is a story of love, a love that can be seen in the service of epic. This article examines the characteristics of love and epic in these two larger works of literature of the two great nations of Iran and Georgia by describing and using library resources. The purpose of this study is to show that a literary work is a good platform for raising various issues that lead to a variety of topics. Manuscript profile -
Open Access Article
46 - Phytochemical Study of Ethanolic Extract of Fraxinus excelsior L. in Different Habitats of Hyrcanian Forests in Mazandaran Province
Masoomeh Soleimany Rahim abadi seyed mohammad hosseini nar hamid jalilvand seyed mohammad hojatti poriya biparvaFraxinus excelsior L. is a forest species with versatile biological and medicinal activities that its extracts are used as a model for making new compounds in the treatment of various human diseases. In this study, in order to investigate how the biochemical characteris MoreFraxinus excelsior L. is a forest species with versatile biological and medicinal activities that its extracts are used as a model for making new compounds in the treatment of various human diseases. In this study, in order to investigate how the biochemical characteristics of this forest species are affected by environmental conditions, four habitats of Perchink, Amreh, Alandan and Qarnsara with an altitude of 200 to 1400 meters, were selected in Tajan and Siahroud watersheds located in Mazandaran province. In each habitat, skin samples were taken from 3 trees (repeated) in summer. Ethanol extracts were obtained by maceration and were analyzed by GC/MS and the physical and chemical properties of the soil samples were measured. The most important compounds of extracts were included: benzeneethanol (30.33-51.35%), d-allose (6.20-31.72%), scopoletin (14.65-26.83%), tyrosol acetate (5.37-9.06%), carvacrol (0-4.93%), homovanillyl alcohol (3.84- 6.53%) which increased with increasing altitude. Also, there was negative relationship between the identified compounds and soil nutrients. Among them, only polyphenol tyrosol acetate behaved differently from the other compounds in a way that showed a negative relationship with the altitude factor and a positive correlation with the amount of carbon and absorbable phosphorus in the soil. Also, the chemical composition of d-allose was not observed in Perchink habitat. These results were showed that the chemical properties of this tree skin are affected by habitat conditions, which caused increases the species' resistance to pathogens. As a result, considering that the amount of active ingredients in this species was higher at higher altitudes and the presence of these compounds increases the resistance to pathogens, it seems planting this species is more productive at higher altitudes to achieve multiple goals in afforestation. Manuscript profile -
Open Access Article
47 - Histopathological effects of zinc oxide (ZnO) nanoparticles on skin and muscle tissues of rats
Sepideh Arbabi-Bidgoli Parisa Saberi-Hasanabadi -
Open Access Article
48 - Histopathological study on acute toxicity of nanochelating based silver nanoparticles in mouse model
Seyedeh Mahsan Hoseinialfatemi Abdollah Karimi Fatemeh Fallah Shahnaz Armin Maryam Hafizi Somaye Kalanaki -
Open Access Article
49 - Histopathological study on acute toxicity of nanochelating based silver nanoparticles in mouse model
Seyedeh Mahsan Hoseini-Alfatemi Fatemeh Fallah Abdollah Karimi Maryam Hafizi Shahnaz Armin Somaye Kalanaki -
Open Access Article
50 - Histopathological effects of zinc oxide nanoparticles (ZnO) on skin and muscle tissues of rats
Parisa Saberi-Hasanabadi Sepideh Arbabi-Bidgoli -
Open Access Article
51 - Skin lesion classification from dermoscopy images using color and shape features
hamid reza javadi Hossein PourghasemIn this study, a new algorithm for dermoscopy image classification into two types of malignant and benign is presented. At first, one preprocessing step to remove noise and also enhance image quality is performed. After that using Otsu thresholding, the lesion is separa MoreIn this study, a new algorithm for dermoscopy image classification into two types of malignant and benign is presented. At first, one preprocessing step to remove noise and also enhance image quality is performed. After that using Otsu thresholding, the lesion is separated from the healthy area. Then color and shape features are extracted from the segmented image. The colored features based on statistical moments of quantized grayscale and quantized color histogram are defined. These features demonastrare distribution of color components. Moreover, the shape features are extracted information of the segmented regions with two scenarios. In the first scenario, the features are represented the expantion of region and in the second scenario, the features are represented the edge variations of the extracted regions. Finally, the classification procedure is performed using K-Neasert Neighbor (KNN), Decision Tree, Support Vector Machine (SVM) and Adaboost. The proposed algorithm is evaluated on a standard database consisting of 200 images. The results show that classification using Adaboost classifier obtains the precision rate, accuracy rate and sensitivity rate of 96%, 96.7% and 95%, respectively. Manuscript profile -
Open Access Article
52 - Modeling, Design and Analysis of a Electrodynamic Levitation System by Considering the Skin Effect
Mohammad Rajabi Sabadani Abbas Najjar Khadabakhsh Ahmad DarabiIn this paper, lift and drag forces of permanent-magnet electrodynamic suspension (PMEDS) System have been studied by considering the skin effect. Electrodynamic suspension is based on repulsive force between two magnetic fields with the same polarity. In this research MoreIn this paper, lift and drag forces of permanent-magnet electrodynamic suspension (PMEDS) System have been studied by considering the skin effect. Electrodynamic suspension is based on repulsive force between two magnetic fields with the same polarity. In this research the electrodynamic suspension system consists of a moving permanent magnet block levitated over a flat conducting plate with 2 mm thickness. At first, the analytical model of the PMEDS is proposed. For this propose, permanent magnet poles are modeled by the current sheets. Then the eddy current is calculated on aluminum sheet by considering the skin effect. Finally, the lift and drag forces are calculated in difference speed. The 2D finite element method is utilized to investigate the effect of speed variations on the performance of PMEDS at two different airgap. Two-dimensional finite element model, the accuracy of proposed analytical model is validated. The results of the finite element method are compared with results obtained by analytical model. It shows the accuracy of the analytical model in the estimation of the lift and drag forces of an electrodynamic suspension system. Manuscript profile -
Open Access Article
53 - Blind Source Separation in Farsi Language by Using Hermitian Angle in Convolutive Enviroment
Atefeh Soltani Seyed Hamid Mahmoodian Seyed Ali HashemiThis paper presents a T-F masking method for convolutive blind source separation based on hermitian angle concept. The hermitian angle is calculated between T-F domain mixture vector and reference vector. Two different reference vectors are assumed for calculating two d MoreThis paper presents a T-F masking method for convolutive blind source separation based on hermitian angle concept. The hermitian angle is calculated between T-F domain mixture vector and reference vector. Two different reference vectors are assumed for calculating two different hermitian angles, and then these angles are clustered with k-means or FCM method to estimate unmixing masks. The well-known permutation problem is solved based on k-means clustering of estimated masks which are partitioned to small groups. The experimental results show an improvement in performance when using two different reference vectors compared to only one. Manuscript profile -
Open Access Article
54 - Study on behavior of Concrete Filled Double Skin Steel Tubular Under Torsion and Cyclic Loading
Ahmad maleki reza khalili Concrete- Filled Double Skin Steel Tubular (CFDST) columns are members of the Concrete- Filled Steel Tubular columns (CFST) family. In CFDST the steel skin and the existing concrete affect each other behavior so that the concrete prevents buckli More Concrete- Filled Double Skin Steel Tubular (CFDST) columns are members of the Concrete- Filled Steel Tubular columns (CFST) family. In CFDST the steel skin and the existing concrete affect each other behavior so that the concrete prevents buckling of the inner and outer steel skins and the both steel skins under load result in the development of the confinement force and subsequently increase the ductility of the concrete and prevent the concrete from brittle damage. To ensure the accuracy of the finite element modeling, the experimental results were compared with the finite element and the accuracy of the modeling was verified. In this research, the section geometry, under monotonic and cyclic loading was investigated. The out-come results show that the CFDST columns have a good ductility, higher energy absorption capacity during an earthquake event and improved behavior under cyclic loading in comparison with CFST columns Manuscript profile -
Open Access Article
55 - The use of peel extract of pomegranate in apple juice as a preservative against Saccharomyces cerevisiae, Lactobacillus plantarum and Alicyclobacillus acidoterrstris
zeinab Rezvanifard mohammad reza Eshaghi Mehdi HasanzadehAbstractThe aim of this work was to study the influence of pomegranate peel methanol extract on the Lactobacillus plantarum PTCC 1058, Saccharomyces cerevisiae PTCC 5269 and Alicyclobacillus acidoterrestris ATCC 49025 in apple juice. Three different concentration of pom MoreAbstractThe aim of this work was to study the influence of pomegranate peel methanol extract on the Lactobacillus plantarum PTCC 1058, Saccharomyces cerevisiae PTCC 5269 and Alicyclobacillus acidoterrestris ATCC 49025 in apple juice. Three different concentration of pomegranate peel extract (250, 500 and 1000 μg /ml) and control sample were prepared. The samples were stored at 4 °C for 60 days and acidity, pH value, microbial analysis, brix value were conducted at zero, 30 and 60 days. Physicochemical properties showed that acidity soured and pH decreased with increasing extract concentration. Turbidity was increased and brix value was decreased in storage time. Turbidity amount in 60th day were increased but treatment with 500 μg /ml had minimum turbidity. These results suggest the potential of pomegranate peel methanol extract as bio preservatives and have effect on decrease of turbidity in apple juice under refrigerated storage. Manuscript profile -
Open Access Article
56 - بررسی هیستومورفومتریک تاثیر صمغ درخت کاج بر ترمیم زخم پوستی موش صحرایی نژاد ویستار
احمد روزبهانی الهام مقتدایی مصطفی نوربخشمقدمه و هدف :از مهمترین خواص درمانی ذکر شده برای گونههای مختلف رده کاج، خاصیت ضد میکروبی، خاصیت ضد التهابی، تسکیندهندگی، برطرف کننده­ی خارش­های پوستی، درمان کننده زخمها، جوشها و بثورات جلدی و بهبود اولسرها و زخمهای مزمن می باشد. در متون طبی کهن ایران از تر Moreمقدمه و هدف :از مهمترین خواص درمانی ذکر شده برای گونههای مختلف رده کاج، خاصیت ضد میکروبی، خاصیت ضد التهابی، تسکیندهندگی، برطرف کننده­ی خارش­های پوستی، درمان کننده زخمها، جوشها و بثورات جلدی و بهبود اولسرها و زخمهای مزمن می باشد. در متون طبی کهن ایران از ترکیبات قسمتهای مختلف انواع رده کاج به خصوص صمغ آن برای درمان زخمهای مزمن استفاده شده است. پژوهش حاضر به منظور بررسی اثر عصاره صمغ درخت کاج تهرانی بر روند ترمیم زخم پوستی در حیوان رت به اجرا درآمد. روش تحقیق : به همین منظور پس از عصارهگیری؛ پماد 40 درصد با پایه اوسرین از این نوع صمغ تهیه شد. پس از آن در مقام مقایسه 24 سر رت نژاد ویستار به 4 گروه 6 تایی تقسیم شدند.گروه دریافت کننده صمغ (گروه تجربی) گروه کنترل مثبت (پماد فنی توئین)،گروه کنترل منفی (گروه اوسرین) و گروه شاهد که تیماری بر روی آنها صورت نگرفت. سپس بر روی ناحیه کمری رت‏ ها زخمی با مساحت حدود 2 در 2 سانتیمتر پس از بیهوشی ایجاد شد. پس از ایجاد زخم عمل ضماد کردن پمادها تا 21 روز پس از برش انجام گردید. نتایج و بحث: در روز 3 ،7 و 21 پس از ایجاد زخم صفات مورفولوژیک و هیستوپاتولوژیک زخمها مورد بررسی قرار گرفتند. نتایج بررسی آماری مساحت زخم در روزهای مختلف حاکی از آن بود که در روزهای مختلف سطح زخم به صورت معناداری کاهش یافت(05/0>p) و مشخص شد که تاثیر فنی توئین و صمغ درخت کاج یکسان میباشد و کاهش زخم در این روش تفاوت معناداری نداشته است. از طرفی کاهش سطح زخم در هر سه روش آزمایش شده از گروه شاهد بیشتر بود. از نظر هیستوپاتولوژیک نیز در گروه صمغ درخت کاج نظم رشتههای کلاژن بهترین شکل و سلولهای التهابی در کمترین میزان خود بودند که احتمالا به دلیل اثر بر روی فیبروبلاستها میباشد. توصیههای کاربردی/صنعتی: با توجه به اثرات مثبت صمغ درخت کاج در التیام زخم می توان از آن در ساخت پمادهای سوختگی استفاده نمود. Manuscript profile -
Open Access Article
57 - گلهای رز ایرانی، یک ضد باکتری طبیعی علیه عامل اصلی عفونت سوختگی پوست، سودوموناس آئروژینوزا
مائده رزقی سید رضا حسینی دوست ژینوس عسگرپناهمقدمه و هدف : رز ایرانی (Rosa foetida) متعلق به تیره گل سرخ می باشد و یکی از گونه های بومی ایرانی به حساب می آید که تاکنون اثرات بیولوژیک گل های آن بررسی نگردیده است. از آنجا که گل های این گیاه در طب سنتی ایران به عنوان مرهم جهت بهبود سوختگی های عفونی پوست به کار می رود Moreمقدمه و هدف : رز ایرانی (Rosa foetida) متعلق به تیره گل سرخ می باشد و یکی از گونه های بومی ایرانی به حساب می آید که تاکنون اثرات بیولوژیک گل های آن بررسی نگردیده است. از آنجا که گل های این گیاه در طب سنتی ایران به عنوان مرهم جهت بهبود سوختگی های عفونی پوست به کار می رود، بر آن شدیم تا برای اولین بار اثر ضد میکروبی عصاره های مختلف گل ها را علیه عامل اصلی عفونت های سوختگی، سودوموناس آئروژینوزا بررسی نماییم. روش تحقیق: بررسی اثر ضد میکروب عصاره ها و تعیین حداقل غلظت مهار رشد باکتری به ترتیب با استفاده از روش چاهک پلیت و روش رقت سازی متوالی در میکروپلیت انجام شد. نتایچ و بحث: تمام عصاره های حاصل از گل ها دارای اثر مهاری بر رشد باکتری بودند که از بین آنها عصاره های آبی و متانولی دارای قوی ترین اثر را نشان دادند. قطر هاله عدم رشد (با غلظت 125 میلی گرم/میلی لیتر) و حداقل غلظت مهار رشد باکتری برای هر دو عصاره فوق نسبتا با اثر داروی استاندارد، ایمیپنم/سیلاستاتین (8/8 میکروگرم/میلی لیتر) یکسان بود. توصیه کاربردی / صنعتی: نتایج مشاهده شده نشان می دهد که گل های رز ایرانی دارای ترکیبات موثره با اثر ضد باکتری علیه سوش های استاندارد و پاتوژن سودوموناس آئروژینوزا جدا شده از پنج بیمار مبتلا به عفونت سوختگی پوست است و کاربرد سنتی این گیاه را در عفونت های سوختگی پوست توجیه می نماید. Manuscript profile -
Open Access Article
58 - بررسی بالینی اثربخشی داروهای یونانی بر بیماری های پوستی
موشیر انصاری نسرین جهان عبید علی تنزیل احمدBackground & Aim: Throughout the past three decades, scientific attention has been increased in examining Unani drugs for a potential therapeutic or preventive agent in the management of a number of health disorders in general and skin disorder in particular. T MoreBackground & Aim: Throughout the past three decades, scientific attention has been increased in examining Unani drugs for a potential therapeutic or preventive agent in the management of a number of health disorders in general and skin disorder in particular. The purpose of this systematic review is to analyze and categorize the current state of scientific evidence from clinical studies regarding the efficacy of Unani drugs in skin diseases. Experimental: Electronic and non-electronic systematic searches were carried out to identify all relevant clinical research on Unani drugs. Reference lists of articles that met the inclusion criteria were searched. Only studies reported in English were reviewed. Studies on single Unani drugs and compound formulations in various skin diseases were included, in accordance with the PRISMA statement that included studies must measure a physiological and/or a behavioral outcome. Results: The studies that met our inclusion criteria are effects of Unani drugs on Acne (n=5), Melasma (n=2), Pityriasis (n=1), Vitiligo (n=2), Urticaria (n=2), Ring worm (n=2), Psoriasis (n= 3), Eczema (n = 2), and Scabies (n = 1). The data from these studies support the efficacy of Unani drugs as compared to placebo and standard drugs in improving Acne, Melasma, Pityriasis, Vitiligo, Urticaria, Ring worm, Psoriasis, Eczema and Scabies. Recommended applications/industries: Findings from initial clinical trials suggest that Unani drugs may improve the clinical manifestations of skin diseases. However, larger multi-site clinical trials are needed to extend these preliminary findings. Manuscript profile -
Open Access Article
59 - The Influences of Adding Polyethylene Glycol and Activated Sodium Bentonite on the Performance, Blood Parameters, and Muscle Mineral Content of Saanen Goats Fed Pistachio Byproducts
M. Kordi A.A. Naserian F. Samadian -
Open Access Article
60 - Thermoregulatory Mechanisms of Jersey Adult Cattle and Calves Based on Different Body Sites Temperature
ی. بدخشان م.ر. محمدآبادی -
Open Access Article
61 - بررسی کیفیت پوست و ویژگیهای فیزیکی چرم براساس سن، جنس و محل قرار گرفتن در بدن در بزهای پرورش دادهشده در مناطق نیمهمرطوب و مرتفع
م. صالحی ا. لواف ط. فرهوشبرای بررسی ویژگی‎های پوست و چرم بزهای موئی با توجه به سن و جنس آنها، تعداد 120 پوست بز از بخش غربی ایران انتخاب شدند. نتایج نشان دهنده معنیدار بودن سن و جنس بر وزن و مساحت پوست و چرم بود. علاوه بر این، سن و جنس، اثرات معنی‎داری برروی ضخامت چرم و پوست در نواحی م Moreبرای بررسی ویژگی‎های پوست و چرم بزهای موئی با توجه به سن و جنس آنها، تعداد 120 پوست بز از بخش غربی ایران انتخاب شدند. نتایج نشان دهنده معنیدار بودن سن و جنس بر وزن و مساحت پوست و چرم بود. علاوه بر این، سن و جنس، اثرات معنی‎داری برروی ضخامت چرم و پوست در نواحی مختلف بدن به جز شکم داشتند. متوسط وزن کل پوست و چرم به ترتیب 9/27 ± 8/1074 و 9/25 ± 2/427 گرم بود. همچنین این صفات ضرایب تغییرات بالائی را نشان دادند (به ترتیب 03/28 و 3/66) که مقدار آن برای نواحی پوست از 30 تا 80 dm2 و برای نواحی چرم از 38 تا 115 dm2 متغیر بود. قسمت‎های مختلف بدن (شانه، لگن و دنده‏ها) و موقعیت نمونه (موازی و عمود) به طور معنی‎داری تحت تاثیر متوسط نیروی شکستگی، استحکام کششی و ازدیاد طول قطعات تست شده قرار داشتند. طیف گسترده‏ای از مقادیر نیروی شکستگی، استحکام کششی و ازدیاد طول در چرم بزها مشاهده شد (به ترتیب 5/4-0/66 kgf، 4/63-3/558 kgf cm-2 و 0/22-3/141 درصد). نتایج این تحقیق نشان داد که بین صفات کمی و کیفی پوست و چرم بزهای مختلف، اختلاف وجود داشته و برای بدست آوردن یک ویژگی بهتر برای کیفیت محصولات بز، بایستی اختلافات ناشی از سن و جنس دام‎ها را مد نظر قرار داد. Manuscript profile -
Open Access Article
62 - Dual variables of government consolidation and decline from Saadi's point of view based on Skinner's hermeneutic theory
Ali Asmand juneganySaadi is one of the poets who has raised the concern of governance in his poetry more than others. In interaction and confrontation with the rulers, he has presented several factors that are effective in stabilizing and consolidating as well as the decline and fall of g MoreSaadi is one of the poets who has raised the concern of governance in his poetry more than others. In interaction and confrontation with the rulers, he has presented several factors that are effective in stabilizing and consolidating as well as the decline and fall of governments. In this article, we tried to investigate the dual variables of the strength of the government and its decline and fall in the textual and extratextual layers of Saadi's works and his deviation from the common and existing customs with the model of Skinner's hermeneutic method in order to get a precise understanding of the foundations of his thought. This research was done with descriptive method and content analysis and hermeneutic study of Skinner's text. In this research, we came to the conclusion that Saadi, being familiar with the fields of theoretical thought, including the norms of the Qur'an and Hadith, and the social norms before him, while understanding the existing practical conditions regarding social political issues, had an avoidance of norms and in many cases, both explicitly and implicitly. He has put practical solutions in front of statesmen and nobles regarding the reasons for the fall of rulers and the reasons for the stabilization of governments. Manuscript profile -
Open Access Article
63 - Proposing a New Speech Enhancement Method based on Spectral Subtraction and Binary Masking With a Bank of 128 Gamma-tone Filters
Mozhgan Monjizade Saeed Ayat -
Open Access Article
64 - Study of the most important skin tumors in domestic animals
somayeh monazzah-harsiniSkin is one of the most important organs in the body, and as the other organs of the body they may be affected by tumor lesion because of various factors. The most significant signs of these tumors including: bumps on the skin, bleeding from the skin, and not recovering MoreSkin is one of the most important organs in the body, and as the other organs of the body they may be affected by tumor lesion because of various factors. The most significant signs of these tumors including: bumps on the skin, bleeding from the skin, and not recovering ulcers, and ultimately alopecia or hairless part of the skin of animals. Most these tumors have a range from benign to malignant. In the most tumors malignancy was found to be relevant with degree of differentiation of tumor cells, so that the more differentiate tumor cells are the less malignant, and the less differentiate tumor cells will be the more malignant. In this paper, the PubMed and Google scholar articles were extracted and studied using electronic articles. Finally, a list of the most important skin tumors, the most important animal species involved, the clinical and histopathologic faces and their treatment are presented. Manuscript profile -
Open Access Article
65 - Report crustacean parasite infection Lernaea in warm water fish breeding farms, the city of Shushtar and treatment method Multiple treatment option
seyed reza mousavi Ali bagherpor Behnaz NickafrazHooked worm or Larnae parasite is a hard-shell skin and in fact most of the parasite is hydrothermal fish, especially carp. Fishlings are most commonly found in hydrotherapeutic swimming pools, especially in carp species. This parasite can be replicated and will be tran MoreHooked worm or Larnae parasite is a hard-shell skin and in fact most of the parasite is hydrothermal fish, especially carp. Fishlings are most commonly found in hydrotherapeutic swimming pools, especially in carp species. This parasite can be replicated and will be transferred from host to host. In November 1396, five common carp species were referred from a fish farm in the Cham area to Shooshtar Shoshtar University College of Veterinary Medicine, Islamic Azad University, Shoushtar Branch. In the sample of samples, They were In a typical observation, your fish can be hatched to different levels. The vivid green field was hanging from the skin of the fish in the abdominal region of the chest wall, while the red and swollen region was visible at their points of attachment, as well as the eyeshadow and the exophthaemia of the eyes. For treatment, the parasite removal method was used with phenocrysts and disinfected solution, then the cannula with methylene blue and salt. After the end of the treatment period, 5 pieces of fish, the number of mortality were 1 piece and 4 units were treated with multiple treatment option. They were positive. Manuscript profile -
Open Access Article
66 - Traditional remedy of local application of raw garlic on the metacarpal region of horse for reduction of tissue inflammation: extensive skin injury creation
Abolfazl Barzegar Bafrouei Moosa Javdani Zahra Nikousefat Jahangir Modaresi Jamshid KabiriA Kurdish 6 year-stallion referred to the Veterinary Clinic of ShahreKord University with complaint of enormous skin and subcutaneous tissue injuries and ulcer in dorsal and palmar side of both metacarpal regions. Based on the patient's history, walking of the stallion MoreA Kurdish 6 year-stallion referred to the Veterinary Clinic of ShahreKord University with complaint of enormous skin and subcutaneous tissue injuries and ulcer in dorsal and palmar side of both metacarpal regions. Based on the patient's history, walking of the stallion on the tarmac path immediately after shoeing caused severe swelling of metacarpal region and traditional remedy were performed by dressing crashed fresh garlic on the affected area for 3 days. Clinical examination and radiographic evaluation showed vast skin and subcutaneous wound and injury, tissue necrosis, massive granulation tissue formation and metacarpal bone involvement. In laboratory investigation of hemogram, severe leukocytosis along with mild left shift, toxic neutrophil and fibrinogen increase were observed. Wound management consisting of second intension of wound healing like as debridement of granulated and necrotic tissue and lastly, dressing the ulcers with local silver sulfadiazine, NSAID prescription and stall resting were ordered. Spite of many advantageous of fresh garlic as an herbal treatment, there were rarely documents of skin burn due to local application of raw garlic in human and the present study would be counted as the first report in horse after traditional remedy. Manuscript profile -
Open Access Article
67 - The Study of skin pathological changes in goldfish (Carassius auratus) in Ahwaz, Iran
S. Peyghan نگین SalamatThe present investigation aimed to study the histological structure of skin and its pathological changes in goldfish (Carassius auratus) without consideration to responsible the agent. 20 goldfish with clinical signs of skin diseases were collected from aquariums in dif MoreThe present investigation aimed to study the histological structure of skin and its pathological changes in goldfish (Carassius auratus) without consideration to responsible the agent. 20 goldfish with clinical signs of skin diseases were collected from aquariums in different part of the city. Skin tissue sections with five-micrometer thickness were prepared to examine by light microscope. The results showed that goldfish normal skin consist of layers including epidermis, dermis and hypodermis. Mucous cells, alarm cells and epithelial cells were observed in epidermis. Damaged skins showed pathological changes such as hyperplasia of epidermal cells, decrease of epidermal cell layers, leukocyte infiltration and epidermal destruction, hypertrophy of epidermal squamous cells, epidermal desquamination, intercellular edema, hemorrhage and transformation of red blood cells. Manuscript profile -
Open Access Article
68 - Therapeutic effect of cold plasma on burnt skin in adult mice
Shadi Dorehlo simin mohamadi Gorji Nasim Hayati RodbariBurn wounds significantly heal the patient and these wounds are prone to infection with electrical energy and scar formation. The use of CO2 laser or nitrogen plasma along with the old methods of sterilization and whisper dressing to accelerate the process of blood clot MoreBurn wounds significantly heal the patient and these wounds are prone to infection with electrical energy and scar formation. The use of CO2 laser or nitrogen plasma along with the old methods of sterilization and whisper dressing to accelerate the process of blood clotting and wound healing. It may repair the natural process and be more effective than other treatments. Therefore, the aim of this study was to evaluate the effect of cold plasma on heat burn wound on the skin of adult Syrian mice in vivo. 24 adult male mice were randomly divided into control, fuel control, sham and experimental groups. After anesthesia and under sterile conditions, a circular wound with a diameter of 8 mm was created on the back of the mice's neck through hot body contact and caused burns as a zero day. Mice in experimental groups 1 to 3 were then treated daily for 30, 60 and 120 seconds, respectively, by cold or plasma irradiation of helium gas for one week. At the end of the treatment period, the sample bed was tested. The samples were tagged in Bowen and after molding with paraffin, 5 micron thick sections were prepared and stained with hematoxylin and stained. Wound healing is achieved by examining parameters such as the thickness of the stratum corneum, epidermis, dermis, hypodermis, the number of hair follicles and the diameter and number of blood vessels in the skin. Macroscopic examination of the wound site showed that the team of mice with cold plasma reduced the diameter of the burned area. Also, the thickness of skin layers (horny layers, epidermis, dermis and hypodermis) in experimental groups increased significantly (P <0.001) compared to the control group of fuel, as well as the number (P <0.001) and diameter of vessels. Dermal (P <0.01) was also increased compared to the control group of the fuel group. Wound area also decreased significantly (p <0.001) compared to the control group of fuel on the seventh day. The results showed that cold plasma irradiation of helium gas is effective in all performance indicators and by inducing it during burns can help accelerate wound healing. Manuscript profile -
Open Access Article
69 - Review of the photodynamic therapy with the approach of different photosensitizers
Parnia Hemmati Seyed Mehdi Tabaie Mina sadat NaderiPhotodynamic therapy is a minimally invasive treatment for diseases such as cancer. The photosensitizer, which acts as a catalyst upon absorption of light, converts oxygen into cytotoxic reactive oxygen species that destroy malignant cells through apoptosis or necrosis, MorePhotodynamic therapy is a minimally invasive treatment for diseases such as cancer. The photosensitizer, which acts as a catalyst upon absorption of light, converts oxygen into cytotoxic reactive oxygen species that destroy malignant cells through apoptosis or necrosis, destroy tumor vasculature, and Stimulate immunity. An active photosensitizer activated by a specific biomarker is able to distinguish healthy from diseased cells, thereby reducing off-target photodamage. The purpose of this study is to introduce and evaluate the performance of different types of photosensitizers in the treatment of various diseases, including skin diseases and skin cancer with the photodynamic therapy method. In this review study, the articles of the last 10 years on the sites google scholar, PubMed, science direct, and Scopus, with the titles of photosensitizers, photodynamic therapy, cancer, skin, and low-power laser were reviewed. There are different treatment methods for cancer, and photodynamic therapy is a promising treatment method for all types of cancer. One of the advantages of this method is the use of non-ionizing radiation, which leads to minimal damage to DNA and surrounding tissues, so this method can improve the method by using different photosensitizers with different optical wavelengths according to the target tissue. treatments with their unique mechanism to have a helpful effect. Manuscript profile -
Open Access Article
70 - Design and manufacture of electrospun wound dressing based on polyvinylpyrrolidone fibers modified with aloe vera compounds for the treatment of skin edema
seyedeh Shadi Amini Dehkordi Nargess Aghamohamadi Javad Shabani ShayehIn this research, a new type of wound dressing based on polyvinyl pyrrolidone polymer (PVP) modified by extracted compounds from aloe vera (Av) was prepared by electrospinning method. After achieving optimal preparation conditions using experimental design method, the p MoreIn this research, a new type of wound dressing based on polyvinyl pyrrolidone polymer (PVP) modified by extracted compounds from aloe vera (Av) was prepared by electrospinning method. After achieving optimal preparation conditions using experimental design method, the prepared material was characterized using infrared Fourier transform spectroscopy, scanning electron microscopy, X-ray diffraction, differential scanning calorimetry analysis, and thermogravimetric analysis. The results of the studies showed that by using the optimal conditions, smooth filament of PVP without node with the diameter of about 100 nm can be achieved. PVP-Av and PVP-Av-Film fiber diameter as well as fibers with a special therapeutic coating were about 105 and 120 nm, respectively with a suitable surface to volume ratio. The results of the investigations showed that the use of polymer coating on the wound dressing not only increase its mechanical resistance, but also increase the hydrophilicity of this wound dressing. In addition, the results of biological investigations showed that this wound dressing has very little toxicity for biological cells and can be used to treat skin edema. Manuscript profile -
Open Access Article
71 - Touba and the Meaning of Night: A Mythical Criticism
Khadijeh Bahrāmi RahnemāMythological criticism is an effective tool for examining early ideas, historical events and human ideals throughout history, and through it can be traced the actions of ancient humans. Various areas can be explored, including mythical criticism, in Touba and the Meanin MoreMythological criticism is an effective tool for examining early ideas, historical events and human ideals throughout history, and through it can be traced the actions of ancient humans. Various areas can be explored, including mythical criticism, in Touba and the Meaning of Night, a novel by Shahrnush Parsipur. The aim of the present research is to study the components of mythical criticism in Touba and the Meaning of Night by using descriptive-analytical method. The results indicate that in the novel, there is a direct and significant relationship between women and the elements of nature, which has given direction and meaning to the mythological actions of women. For example, by using the symbolic and archetypal concept of water, it is possible to explain the placement of Munesan next to the fountainhead and Leila next to the pond, who, respectively, seek to achieve fertility and the process of individuation. We can also mention the influence of the Epic of Gilgamesh on Touba and the Meaning of Night; because Touba, like Gilgamesh, uses the archetype of journey to achieve self-examination and perfection. Manuscript profile -
Open Access Article
72 - The effect of walnut''s green skin on coloration of Oscar fish (Astronotus ocellatus)
M. Abbasi Oghda A. Vosooghi A. MatinfarThe effect of oral green skin of walnuts on the coloration of Oscar fish (Astronotus ocellatus) was studied. Albino Oscar fish with an average weight of 60 grams 5/01 ± 0/18 and 54/84 ± 2/23 mm average length in the form of 3 experimental and one control and each with t MoreThe effect of oral green skin of walnuts on the coloration of Oscar fish (Astronotus ocellatus) was studied. Albino Oscar fish with an average weight of 60 grams 5/01 ± 0/18 and 54/84 ± 2/23 mm average length in the form of 3 experimental and one control and each with three repetitions were divided. Twelve aquariums with dimensions of 50 × 40 × 33 cm was used. Control was fed with no food additives (food stand). For the first treatment food containing 0.1 percent walnut hull was used, 0.2 percent was used for the second treatment with the diet and in the third treatment fish were fed with food containing 0.3 percent walnut hull. The breeding period lasted 8 weeks (56 days). Every 20 days biometrics (Biometry) was carried out. Average water temperature in the aquarium during the study period was 28.07 ± 1.09 °C, with an average of 5.38 ± 0.15 milligrams per liter of dissolved oxygen, average pH was measured to be 8.03 ± 0.33 and average TDS, 33.27 ± 1.32 mg. After the breeding period, 3 fish from each treatment were randomly selected to assess the rate of change of color obtained using L* a* b* colorimetric system using a CHROMA METER CR-40. Colorimetric analysis of fish skin from treatments showed that oral administration of green walnut caused significant skin discoloration. Component b* representing the yellow color, was positive in the treatment 1, showed significant differencecompared to control (P0/05). The results showed that using the green skin of walnuts in the diet can increase the Oscar fish skin color towards yellow. It was shown that the level of 0.1 percent green skin of walnuts in the diet was the best level for increasing the yellow color in fish were detected. Manuscript profile -
Open Access Article
73 - Histological study of the Flower horn fish gills (Flower horn) fed different levels of hydrolyzed cow skin
A. Veisi A. Vosoughi A. DadgarThe present study fulfilled to investigate possible changes in the structure of the gills of Flower horn fishes fed diets containing different levels of cow skin hydrolyze. For this purpose, 216 Flower horn fishes with mean weight of 0.95 ± 0.2 g and the mean len MoreThe present study fulfilled to investigate possible changes in the structure of the gills of Flower horn fishes fed diets containing different levels of cow skin hydrolyze. For this purpose, 216 Flower horn fishes with mean weight of 0.95 ± 0.2 g and the mean length of 3.7 ± 0.2 cm were fed for 100 days with levels of 20 percent (T1), 40 percent (T2), 60 percent (T3), 80 percent (T4), 100 percent (T5) replacement hydrolyzed cow skin instead of fish meal. Control diet (T6) had no hydrolyzed cow skin. The results indicated that the gills of fishes fed with level 0, 20 and 40 percent cow skin hydrolyze were healthy and certain symptoms in the gills were not found. In the gills of fishes fed with diet containing 60 percent cow skin hydrolyze, symptoms such as mild hyperplasia in the secondary lamella and mild skin lesions were observed. In some gill tissue samples from treatment (T4) some secondary lamella were wide. In the gill treatment T5, tissue lesions were more. Cutaneous lesions in the secondary lamella, shortage and lengthening of some secondary strings and Aneurysm (hyperemia) in the secondary lamella, were lesions that were observed in the gill tissue samples of treatment T5. From the above findings, it can be concluded that with the increase in cow skin hydrolyze, from levels of 40%, adverse effects in gill tissue was increased. Manuscript profile -
Open Access Article
74 - The effect of walnut’s green skin on growth of Oscar fish (Astronotus ocellatus)
M. Abbasi Oghda A. Vosooghi A. MatinfarIn this study, the effect of oral green skin of walnuts on the coloration of Oscar fish (Astronotus ocellatus) was studied. Sixty albino Oscar fish with an average weight of 5/01 ± 0/18 g and 54/84 ± 2/23 mm average length were divided in into three MoreIn this study, the effect of oral green skin of walnuts on the coloration of Oscar fish (Astronotus ocellatus) was studied. Sixty albino Oscar fish with an average weight of 5/01 ± 0/18 g and 54/84 ± 2/23 mm average length were divided in into three test experiments and one control and each with three repetitions. Twelve aquariums in the dimensions of 50 × 40 × 33 cm were used. The control was fed with a diet containing no food additives. The fish in treatment number one were fed with food containing %0.1 walnut hulls, the second treatment contained %0.2 walnut hulls in the fish diet and the third treatment was fed with food containing % 0.3 walnut hulls. The breeding period lasted eight weeks (56 days). Every 20 days biometrics (Biometry) were performed which included gravimetric analysis using a digital scale with 0.01g precision and a ruler with an accuracy of 0.1 cm for length analysis. Average water temperature in the aquarium during the study period was 28/07 ± 1/09 ° C. An average of 5/38 ± 0/15 milligrams per liter of dissolved oxygen, average pH of 8/03 ± 0/33 and an average TDS of 33/27 ± 1/32 mg was measured. At the end of the period of investigation, results showed that in terms of growth, the control with an average weight of 17/06 ± 1/21 grams and weight gain of 22/15 ± 1/08 grams had significantly (P<0/05) the highest growth rate compared with the other treatments. The third treatment with an average weight of 6/95 ± 0/56 grams and weight gain of 2/12 ± 0/64 grams showed the lowest growth rates. The control treatment also showed increased body weight and had the highest average of 337/01 ± 38/62 percent and was significantly different (P<0/05) from the other treatments. Treatment no. 3 with an average of 44/60 ± 15/48 percent had the lowest percentage of weight gain. Treatment no. 2 with an average of 95 percent have the highest rateof survival and was significantly different (P<0/05) from treatment no. 1, but was not significantly different (P≥0/05) compared to other treatments. Treatment no. 1 with an average survival of 55 percent had the lowest survival rate.The results showed that using the green skin of walnuts in the diet can reduce the growth factors in Oscar fish. However, 0.3 percent green skin of walnuts in the diet was most effective in slowing the fish growth rate. Manuscript profile -
Open Access Article
75 - The Effect of walnut shell on coloration of Koi fish (Cyprinus carpio)
H. Ghazvini A. Vosoughi A. MatinfarIn this study the effect of oral administration of green skin of walnuts on the growth and color of Koi fish (Cyprinus carpio) has been studied in 60 Koi fishof average weight of 1.50±0.06g and average length of 53.00±1.48mm in 3 treatments and 1 control a MoreIn this study the effect of oral administration of green skin of walnuts on the growth and color of Koi fish (Cyprinus carpio) has been studied in 60 Koi fishof average weight of 1.50±0.06g and average length of 53.00±1.48mm in 3 treatments and 1 control and each with 3 replicates.Twelve aquariumsof 33×40×50 dimension were used. The control group had no food additives (basic food was fed). First treatment with food containing 0.1 percent, second treatment with food containing 0.2 per cent, third treatment with food containing 0.3 percent green skin of walnut was fed for 8 weeks (56day) breeding period. Every 20 days once, biometry including gravimetric and length measurement was done. Also, at the end of the period from each treatment, 3 fish were selected at to random.To asses the color change, the colorimetric system L*a*b* was used, using device CHROMA METER CR_40. There was no significant difference regarding all three factors. Generally, it can be concluded that the use of green skin of walnuts to fish food ration, cause no impact on some growth factors and as well as survival rate and food conversion rate, but the apparent color index impact was significanot(P≥0.05) Manuscript profile -
Open Access Article
76 - Neural Network Performance Analysis for Real Time Hand Gesture Tracking Based on Hu Moment and Hybrid Features
Fardad Farrokhi Mehdi Heydarian Kaveh Kangarloo -
Open Access Article
77 - Diagnosing skin disease using deep features based on artificial intelligence
Hassan Masoumi Fatemeh Mosalanejad Mehdi Taghizadeh Mohammad GhanbarianMisdiagnosis of skin diseases is a common occurrence. Psoriasis is a skin disease that has many similarities with other diseases, and its incorrect diagnosis causes many problems in the treatment process. Misdiagnosis of this disease causes doctors to face problems duri MoreMisdiagnosis of skin diseases is a common occurrence. Psoriasis is a skin disease that has many similarities with other diseases, and its incorrect diagnosis causes many problems in the treatment process. Misdiagnosis of this disease causes doctors to face problems during treatment. The lack of images of the disease and the database of skin diseases reduces the diagnosis and the coordination of diagnostic methods, therefore, diagnosis using different images is very useful. Today, diagnosis methods using deep features in medical images have received much attention. Artificial intelligence is one of the automatic methods of diagnosis. These methods can detect new data entering the system and keep it in memory. Therefore, in this article, two different groups of data have been identified using deep features based on artificial intelligence. In this method, the data of the first group in the form of training and testing and the data of the second group are studied gradually. If they are correctly identified, the next 0.1 chunks of data enter the network without testing. If they are wrongly recognized, they enter the training section and this reduces the training process. In this work, by training 20% of the data, i.e. the first 10% and the fourth 10%, there was no need for training because the accuracy was not less than98%. In this article, deep features of images were first extracted using convolutional neural network, and then psoriasis and eczema were diagnosed with average accuracy of98.3%and sensitivity of 97.9% in skin images using artificial intelligence. Manuscript profile -
Open Access Article
78 - Principles and components of democracy in the thoughts of Mohammad Mojtahed Shabestari; Emphasizing on the methodology of Quentin Skinner
Zekrollah Manafi Ehsan Shakeri Alireza Esmailzad -
Open Access Article
79 - The Investigation and Evaluation of Some Important Mechanical Tests for the Consumed Varieties of Persian Walnut
A.R. Makarichian G.R. Chegini -
Open Access Article
80 - Efficacy of topical application of carvacrol, amitraz, and combination of carvacrol-amitraz for the treatment of dogs with generalized demodicosis
Sina Fereydooni Farnoosh Arfaee Mohammad Reza Youssefi Fatemeh Zahra Gharib Mohaddeseh Abouhosseini-TabariCanine demodicosis is an inflammatory parasitic skin disease caused by an increasing population of Demodex spp. mite. Thus, there will be an urgent need for effective, safe, and available treatment for demodicosis. This study aimed to evaluate the activity of Carvacrol MoreCanine demodicosis is an inflammatory parasitic skin disease caused by an increasing population of Demodex spp. mite. Thus, there will be an urgent need for effective, safe, and available treatment for demodicosis. This study aimed to evaluate the activity of Carvacrol %5, Amitraz %0.05, and Carvacrol-Amitraz combination on killing Demodex canis mites after topical pour-on use and analyzing the improvement in associated dermatologic signs. Fifteen dogs with naturally acquired generalized demodicosis were randomly allocated to 3 equal study groups. The dogs were selected from the animal shelter in Mazandaran province. Treatment groups included a pour-on solution of 50 ml of Carvacrol %5, 50 ml of Amitraz %0.05, and the combined Carvacrol and Amitraz 1:1 mixture at the same concentrations. Evaluation of clinical factors consisted of mite count by skin scraping, hair re-growth, comedones, erythema, crusts, and scales during seven-day intervals over four weeks. Mite counts significantly decreased in all groups during the study, especially in Carvacrol %5 (p0.05). The highest decrease in mite population was associated with Carvacrol %5 from day 14 up to %90 in demodicosis treatment. This clinical field study demonstrated that pour-on administration of Carvacrol %5 is highly effective in the reduction of mite numbers and improvement in associated dermatologic signs of demodicosis Manuscript profile -
Open Access Article
81 - The Effect of Hydroalcoholic Extract of Berberis vulgaris on Wound Healing of Diabetic Wistar Rats
Mansoureh Pashaee Abdolhossein Shiravi Vida Hojati -
Open Access Article
82 - The Study of the Effect of Alcoholic Extract of Triticum sativum, on the Skin Wound Healing in Diabetic Male Wistar Rats
Asma Movaghar Vida Hojati Abdolhossein Shiravi -
Open Access Article
83 - Antibacterial and Antioxidant Properties of Colorant Extracted from Red Onion Skin
Sara Moosazad Peyman Ghajarbeigi Razzagh Mahmoudi Saeed Shahsavari Roghayeh Vahidi Ali Soltani -
Open Access Article
84 - Fabrication and evaluation of (chitosan / poly-vinyl-pyrrolidone) scaffold properties containing gum tragacanth by freeze-drying method
hamed ghomi Azadeh Sepyani Marjan MirhajChitosan as a component of the extracellular matrix is extensively investigated for preparation of porous scaffolds for tissue engineering. In this study, chitosan and (chitosan/polyvinylpyrrolidone) scaffolds as control and (chitosan/polyvinylpyrrolidone) / tragacanth MoreChitosan as a component of the extracellular matrix is extensively investigated for preparation of porous scaffolds for tissue engineering. In this study, chitosan and (chitosan/polyvinylpyrrolidone) scaffolds as control and (chitosan/polyvinylpyrrolidone) / tragacanth composite scaffolds with 25:75, 50:50, and 75:25 ratios were fabricated by the freeze-drying method. The effect of tragacanth on the structural and antibacterial properties of the samples was evaluated. Surface morphology, mechanical properties, porosity and functional groups on the surface of the samples were evaluated by scanning electron microscopy (SEM), compressive strength test, and FTIR. The results showed the porosity of scaffolds with tragacanth increased in comparison to scaffolds without tragacanth. Biodegradable behavior of the scaffolds was examined by retaining the samples in phosphate buffer solution (PBS) for 14 days and the results showed an increase in the degradation of the (chitosan/polyvinylpyrrolidone) / tragacanth scaffold with the ratio of 75:25. The results showed decreased growth of E.coli and Staphylococcus aureus bacteria in the presence of three-component scaffold with tragacanth. Therefore, according to the results of this study, tragacanth containing scaffolds improve antibacterial properties. Manuscript profile -
Open Access Article
85 - Evaluation of the Effect of Sedar (Ziziphus spina-christi) Extract on Biochemical Parameters of Skin Lesion in NMRI Mice
Shokooh Sharbatdar Nasim Hayati Roodbari Parichehr YaghmaeeThe skin is one of the largest organs of the body and acts as a protective barrier against external harmful factors including microorganisms. It can be damaged and sometimes if the damage is too much, the hypoderm is also involved, so more time is needed for restoration MoreThe skin is one of the largest organs of the body and acts as a protective barrier against external harmful factors including microorganisms. It can be damaged and sometimes if the damage is too much, the hypoderm is also involved, so more time is needed for restoration. The purpose of this research is to investigate cedar plant on skin wound healing in NMRI laboratory mice. 24 mice with a weight of approximately 25-35 grams were bought and after wounding the skin on days 3, 6, 12, 21 they were treated with ointment prepared from cedar and oserin. Mice were randomly divided into three groups: sham, experimental 1, experimental 2. These groups were treated with oserin and Cedar ointment with a dose of 2 mg and 4 mg respectively. Wounds were measured after 3 weeks and their tissue was evaluated by hematoxylin-eosin staining. Biochemical indices of SOD, MDA and TAC were also investigated. Data analysis was done by SPSS version 22 software and Tukey's test. The wound size in Cedar 1 and 2 groups had a significant decrease compared to oserin (p < 0.05). The concentration of MDA in cedar groups 1 and 2 had a significant decrease compared to oserin (p < 0.05). In addition, the activity of SOD and TAC were significantly increased in cedar groups 1 and 2 compared to oserin (p < 0.05). Also, there was a significant increase in the thickness of epidermis and dermis in cedar 1 and 2 compared to oserin (p < 0.05). There was a significant increase in the number of fibroblasts and blood vessels in cedar 1 and 2 compared to oserin (p < 0.05). According to the results of the present study, it can be concluded that cedar extract was effective in wound healing by increasing SOD, TAC and decreasing MDA. Manuscript profile -
Open Access Article
86 - Cytotoxicity Effects of Citrus Skin Extract On Cancer Cell Line MCF-7
عباسعلی دهپور جویباری زهرا حسن پورNowadays, cancer is knownas the main cause of death throughout the word. In recent decades, medical and molecular advances have not only been able to find the reasons and mechanisms of cancer, but they were more successful in early diagnosis and treatment of it. Citrus MoreNowadays, cancer is knownas the main cause of death throughout the word. In recent decades, medical and molecular advances have not only been able to find the reasons and mechanisms of cancer, but they were more successful in early diagnosis and treatment of it. Citrus skin is the accumulation center of many antioxidant and enzymes. Flavonoids and limonene are among the important compounds in the citrus skin and their vital rolesin prevention and treatment of cancer is under study these days. In this research, after cultivation and reproduction of MCF-7cancer cells line and in order to determine, the effectof cellular cytotoxicity of citrus skin extract, these cells were put in exposure to different doses of etanolic extract and after 72 hours, MTT test was done. Results indicate that the ethanolic extract of Orange skin at concentrations 7.5,10 (p ≤ 0.05)and the ethanolic extract of Limon skin at concentrations 2.5,5 (p ≤ 0.01)decrease cell growth significantly in comparition with the control group. the effectof cellular cytotoxicity grows with an increase in the concentrationof extract and the highest percentage of growth inhibition in extract of Orange skin and Limon skin is related to the concentrations of 7.5 and 5 respectively. Thus citrus skin extract is suggested as an effective material in curing cancer in medical advances. Manuscript profile -
Open Access Article
87 - Effects of Lactobacillus casei Bacteria Killed by Chloroform on Cutaneous Wound Healing in Rats on Days 3 and 7
سیما مشایخ میترا حیدری نصرآبادی ویدا حجتی مریم تاج آبادی ابراهیمیUlcer healing means to retrieve the whole physical internal and external structures which includes the complex interactions between different cells and factors- plenty of researchers has paid so much attention to shorten the time of healing just due to cost reduction an MoreUlcer healing means to retrieve the whole physical internal and external structures which includes the complex interactions between different cells and factors- plenty of researchers has paid so much attention to shorten the time of healing just due to cost reduction and ulcer infection. They applied different ways to gain this goal so the basic aim of this research is to investigate the effects of cultivated Lactobacillas casei by chloroform on the Cutaneous woundhealing- we used 220-280 g rats- the rats were kept in 20andplusmn;2andCcedil; and food and water provided for the entirely then the rats were divided to five experimental- control and negative control groups. A quadrangle wound 1.5andtimes;1.5 was created. The control and experiment groups were treated topically oserin and the oserin contains cultivated Lactobacillus casei by chloroform but the negative control group has received no treatment rats skin ulcers in rats exposed to pathological sampling and statistical and histology surveying. Findings showed that there are significant differences between ulcer healing percentages of control and experimental groups and negative control. In next phases of healing in experimental group-comparing control and negative control group the number of notrofils reduced. According to findings Lactobacillus casei bacteria which cultivated in chloroform significantly result in decreasing inflammation and accelerating ulcer healing in rats. Manuscript profile -
Open Access Article
88 - The Effect of Extract of Henna Leaves (Lawsonia inermis) on Skin Wound Healing in Wistar Rats
عبدالحسین شیروی مهدی آل بویه ویدا حجتی حسن اکبریWound healingis one of the most basic human issues that are facing the beginning of creation. So trying to find the ingredients in the least adverse impact on the healing of human aspirations, especially in the use of medicinal plants can be important. Henna is native t MoreWound healingis one of the most basic human issues that are facing the beginning of creation. So trying to find the ingredients in the least adverse impact on the healing of human aspirations, especially in the use of medicinal plants can be important. Henna is native to Mediterranean regions, the Near East and India.Hana in Iran in areas south of the country, including Balochistan, Bam Nrmashyr grows. Mostpartsof matureleaves ofhennausedit.Since extracts of Henna (Lawsonia inermis L.) have anti-inflammatory and disinfectant effects, in this research, the effect of hydroalcoholic extract of this plant has been investigated on wound healing. After collecting and drying plant leaves, the hydroalcoholic extract soaking method were prepared and concentrated.Study of 48 male rats Wistar rats weighing 200-210 g were used in the range.Ulcers 3 cm in length on the back of mice were Haayjad and and then were divided into three groups of sixteen: The first group was kept as control without treatment, the second group of Eucerin(negative control), Group III of the ointment made from the henna plant extract based Eucerinwas used once a day. To study wound healing every day was measured during wound And the percentage of wound healing in different groups during all days of treatment based on one way ANOVA and Tukey test were compared. To histological studies, on days 3, 7, 14 and 21 of each group samples of full thickness wounds were removed.Average time of survey complete wound healing in group 3 (treated with henna extract) was lower than of a group 1 (no treatment) and group 2 (treated with Eucerin). Results indicate that the treatment group has the best effect in wound healing in comparison with other groups. It is possible that the components of henna have anti-inflammatory and antibacterial effects, and reduces inflammation, edema and bleeding and also stimulate collagen formation, faster wound contraction, angiogenesis and vasodilatation. Manuscript profile -
Open Access Article
89 - The Effect of Gelatin-aloevera Nanofibers on Collagen I Gene Expression in the Skin of Male Mice after Microneedling
Asadolah Shahrani Maryam Bananej Parvin Mansouri Henghameh Alibeik Nahid NickhahThe skin is prone to mechanical injuries and damage and the skin collagen changes with age. Herbs and aloe vera gel are used experimentally and traditionally in the skin repair and rejuvenation. In this study, the effect of gelatin-aloe vera nanofibers on the expression MoreThe skin is prone to mechanical injuries and damage and the skin collagen changes with age. Herbs and aloe vera gel are used experimentally and traditionally in the skin repair and rejuvenation. In this study, the effect of gelatin-aloe vera nanofibers on the expression of collagen I gene after skin microneedling was investigated in male mice under standard laboratory conditions. Skin microneedling was performed on the backs of the tested mice. Groups were subjected to treatments with saline, aloe vera gel, and gelatin-aloe vera nanofibers for 48 h. The expression of collagen I gene was evaluated through sampling and purification of tissue RNA by Real time PCR method. According to the results, skin injury resulted in a significant reduction in the expression of the collagen I gene in the treatment groups compared to the control group. In comparison, treatment with aloe vera gel and aloe vera/gelatin nanofibers significantly increased gene expression compared to the model group. Furthermore, the existing Glucomannan increased gene expression at the site of injury by passing through pores. Manuscript profile -
Open Access Article
90 - The Effect of Injection of Fibroblast Cells Isolated from Foreskin on Histological Improvement of Diabetic Wound in Animal Model
Abbas Zabihi Rahim Ahmadi Atefe DehghaniDespite a number of experimental studies, the healing effects of stem cells on chronic wounds still face serious challenges. The present study investigated the effect of injection of fibroblasts isolated from foreskin on the histological improvement of diabetic wounds i MoreDespite a number of experimental studies, the healing effects of stem cells on chronic wounds still face serious challenges. The present study investigated the effect of injection of fibroblasts isolated from foreskin on the histological improvement of diabetic wounds in male rats. 24 male Wistar rats were divided into control and treatment groups during this experimental laboratory study. Diabetes was induced in control and treatment groups using streptozotocin. Using a biopsy punch, a wound was created in the dorsal region of the animals Foreskin derived fibroblasts were injected into the dermis layer in the treatment group. On days 7, 14, and 21 after treatment, the wound healing was evaluated using morphologic observation, histological examination through hematoxylin- eosin staining, and measuring the wound size by Image j. On day 14 after treatment, the wound area was significantly smaller in the treated group than the control group (P<0.001). Histological examination showed that the skin thickness significantly increased in the treatment group on days 14 and 21 compared with control group (P<0.01). Besides, no morphologic complications were observed in the skin tissue following the injection of fibroblast cells. Our findings indicated that fibroblast cells are capable of accelerating the process of diabetic wound healing without morphologic complications in the skin tissue; according to which, the foreskin derived fibroblast cells can be used in the field of cell therapy. Manuscript profile -
Open Access Article
91 - Evaluation of the Effect of Ferula gummosa Extract on Biochemical Parameters of a Skin Wound in NMRI Mice
Parisa Seifali Parichehreh Yaghmaei Nasim Hayati RoodbariWound healing is one of the important problems in medicine. Therefore, this study aimed to investigate the effect of Ferula gummosa extract on skin wound healing in NMRI mice. 24 NMRI mice with skin ulcers, were treated with Ferula gummosa ointment on days 3, 6,12, and MoreWound healing is one of the important problems in medicine. Therefore, this study aimed to investigate the effect of Ferula gummosa extract on skin wound healing in NMRI mice. 24 NMRI mice with skin ulcers, were treated with Ferula gummosa ointment on days 3, 6,12, and 21, and randomly divided into three eucerin groups (daily recipient eucerin ointment), the experimental group1(daily treatment with Ferula gummosa ointment at a dose of 2 mg) and the experimental group 2 (daily treatment with Ferula gummosa ointment at a dose of 4 mg and the ulcers were measured with a calliper and the biochemical indexes of superoxide dismutase (SOD), malondialdehyde (MDA) and total antioxidant capacity (TAC) in tissue, were measured. Then, tissue sections were prepared from the wound and evaluated histopathologically by hematoxylin-eosin staining. The data were analyzed by SPSS 22 software and the Tukey test at a significance level of p < 0.05 and the histograms were drawn in excel. wound size in the Ferula gummosa groups compared to the Eucerin group showed a significant decrease (p < 0.05). The concentration of MDA in groups the Ferula gummosa significantly decreased time-dependent compared with the eucerin group (p < 0.05). SOD activity and TAC concentration also showed a significant increase in time-dependent in groups Ferula gummosa compared to the eucerin group (p < 0.05). Based on histopathological findings, epidermal and dermal thickness increased significantly in groups Barijeh compared to eucerin group (p < 0.05), and the number of fibroblasts and blood vessels in the two groups of Barijeh in a time-dependent manner compared to the Eucerin group showed a significant increase (p < 0.05). According to the results, it was shown that Ferula gummosa is effective in wound healing and repair by increasing SOD and TAC activity and decreasing MDA concentration, as well as histopathological results. Therefore, the findings of this study showed a new perspective on this herbal medicine for us wound healing. . Manuscript profile -
Open Access Article
92 - Evaluation of Changes in miR-20a Expression Changes in War Wounded Exposed to Mustard Gas
Mohadese Valizadeh Masoud Soleimani Shiva Irani Mahmood TavallaeiSulfur mustard or mustard gas is a blistering agent that has been used as a war weapon. Chemical veterans are people who have multiple injuries in different organs, especially in the skin. Studies have shown that the side effects of mustard gas are the result of alkylat MoreSulfur mustard or mustard gas is a blistering agent that has been used as a war weapon. Chemical veterans are people who have multiple injuries in different organs, especially in the skin. Studies have shown that the side effects of mustard gas are the result of alkylation with DNA, RNA, protein, and lipids, which leads to metabolic and genetic changes. The respiratory system and the skin are the main targets of mustard gas alkylation. microRNAs are small non-coding and single-stranded RNAs that play a role in the spatial and spatial regulation of protein synthesis and the stability of messenger RNA. The disruption of the expression of any miRNA gene will be equal to the disruption of the expression of several protein-coding genes, each of which can play an essential role in cell biology, so to investigate the changes in the expression of microRNA, miR-20a, in the skin of chemically injured people. In this study, 30 skin biopsy samples were collected, including 10 samples from patients with moderate SM, 10 samples from patients with severe SM, and 10 control samples. RNA extraction and cDNA synthesis were performed. The expression of the miR-20a gene was investigated using the Real-time PCR method. 5s rRNA gene was used as the internal control. GraphPad Prism 6.07 software was used for the statistical analysis of data. Roc curve was used to check the biomarker value of the miR-20a gene. In this study, according to the results of the Roc curve, the miR-20a gene in the skin has a biomarker value, but it needs more study. Manuscript profile -
Open Access Article
93 - Assessment of Human In-vitro Full Thickness Skin Graft Viability and the Use of Gentamicin Antibiotic on This Process
Marjan Mohamadali Ali Ghiaseddin Shiva Irani Mohammad Amir Amirkhani Mostafa DahmardeheiNowadays, skin grafts use to replace lost or damaged skin around the world. Natural contaminants can exist on the skin and this contamination can be a threat to graft recipients. In this study, after obtaining human full thickness skin graft sample and culturing it in-v MoreNowadays, skin grafts use to replace lost or damaged skin around the world. Natural contaminants can exist on the skin and this contamination can be a threat to graft recipients. In this study, after obtaining human full thickness skin graft sample and culturing it in-vitro condition, skin samples were evaluated for cell viability and the presence of bacterial contamination during 72 hr. The amount of microbial contamination in the presence and absence of antibiotic gentamicin 0.02% was also investigated by standard methods. High cell viability during 72 hr in normal skin tissue samples was confirmed by the acridine orange staining. Electron scanning microscope observations, hematoxylin-eosin, and Masson's trichrome staining images clearly showed the difference between the two experimental groups. Skin graft samples lost the layers of dermis and epidermis (except the stratum corneum layer), in the absence of gentamicin due to contamination with bacteria which can be seen in the obtained images. Finally, the obtained results clearly showed the effect of high microbial contamination on the skin tissue structure, which can be caused by various factors. Manuscript profile -
Open Access Article
94 - Investigating the Changes of miR-21 Expression in the Skin Sample of Veterans Exposed to Mustard Gas during Iran-Iraq War
Mohadese Valizadeh Masoud Soleimani Shiva Irani Mohammad Reza Nourani Mahmood TavallaeiMustard sulfur (SM) is a blister and has destructive effects on the lungs, eyes, and skin. MicroRNAs are non-coding RNA molecules that regulate many important cellular pathways. The clear association of microRNA expression changes in a wide range of diseases and their i MoreMustard sulfur (SM) is a blister and has destructive effects on the lungs, eyes, and skin. MicroRNAs are non-coding RNA molecules that regulate many important cellular pathways. The clear association of microRNA expression changes in a wide range of diseases and their interception in various organs of the body, including the skin, has made them a suitable biomarker. This study aims at evaluating the changes in miR-21 gene expression in chemical warfare victims infected with SM. In this study, skin biopsy specimens including 10 veterans exposed to SM with moderate complications, 10 veterans exposed to SM with severe complications, and 10 control samples were collected, and then total RNA was extracted. cDNA synthesis was performed. MiR-21 gene expression was assessed using real-time PCR. 5 s rRNA gene was used as the internal control. Graph Pad Prism software version 6.07 was used for the statistical analysis of data. Roc curve was used to evaluate the biomarker value of the miR-21 gene. Increased expression of the miR-21 gene was observed in samples of SM veterans compared with normal samples. There was a statistically significant difference in the expression of the miR-21 gene in the skin samples of veterans exposed to SM with moderate complications and veterans exposed to SM with severe complications compared with the samples of control skin (P-value 0.0001). The expression of the miR-21 gene in the skin samples of veterans exposed to SM with severe complications and veterans exposed to SM with moderate complications in old age was not significantly related to the control sample (P-value = 0.8049, P-value = 0.3802). This study showed that the relative expression of miR-21 could be a potential biomarker in distinguishing SM veterans from healthy individuals but needs further researches.. Manuscript profile -
Open Access Article
95 - The Effect of Cornus mas Extract on the Wound Healing of the Diabetic Male Wistar Rats
S. Alhooei-Nazari A. Shiravi Vida HojatiDiabetes is one of the reasons for delayed wound healing; as the fruit of blueberries, Cornus mas, possesses high content of antioxidants, therefore, this study aims to investigate the extract of this fruit on wound healing in a male rat of Wistar strain affected by dia MoreDiabetes is one of the reasons for delayed wound healing; as the fruit of blueberries, Cornus mas, possesses high content of antioxidants, therefore, this study aims to investigate the extract of this fruit on wound healing in a male rat of Wistar strain affected by diabetes.In this study, 48 male rats of Wistar strain were divided into 4 groups of 12. After affecting these groups to diabetes (except control group), there was created a wound at the back of the rat in all 4 groups; the length of the wounds in the groups were investigated up to 21 days; (1) control group: with no blueberries extract and ocerin treated on their wounds, called as healthy group; (2) Shem Group: they include a group of diabetics rats who were treated by ocerin (twice per day); (3) Experimental Group 1: they included a group of diabetics rats who received no ocerin and extract; (4) Experimental Group 2: they include the diabetics group who treated by the ointment of blueberries extract (twice a day).Results of comparing the mean of wounds length in the investigated groups indicate that the experimental group 2 had significant reduction up to p ≤ 0.01 than Shem and experimental1 groups. By reducing the blood glucose and modifying some biochemical factors, blueberries makes treatment effect on diabetes. According to the results of this study, blueberries ointment may accelerate skin wound healing in the healthy and diabetic samples. Manuscript profile -
Open Access Article
96 - Effects of Alcoholic Extract of Artemisia inflorescence on Wound Healing of Diabetic Wistar Rats
F. Harasani Gh. Vaezi Vida HojatiSkin ulcers and diabetic foot ulcers are an important issue in medicine. Diabetes is one of the most common metabolic diseases of the endocrine system. Artemisia pharmacological, particularly effects on diabetes. The aim of this study was to compare the healing effects MoreSkin ulcers and diabetic foot ulcers are an important issue in medicine. Diabetes is one of the most common metabolic diseases of the endocrine system. Artemisia pharmacological, particularly effects on diabetes. The aim of this study was to compare the healing effects of alcoholic extract of Artemisia in the process of healing and skin wounds in normal and diabetic rats is quickly closing. Overall, 20 adult male Wistar rats were used. The rats were divided into four groups of five controls (without diabetes and treatment), sham (diabetes treatment Eucerin), Experimental 1 (diabetes without treatment), Experimental 2 (diabetes treated with alcoholic extract of Artemisia) were divided. Three groups of rats were made diabetic using STZ. Over 2 cm wound on the skin of spinous were created in all groups. The experimental group and the experimental group 2 with wormwood extract 1 Eucerin day with a dose of 100 mg Barba topical treatment over a period of 21 d, respectively. Wound healing was evaluated by macroscopic and microscopic. Wound healing in experimental groups 1 and 2 was treated with than the alcoholic extract of Artemisia control group showed the highest rate. Wormwood extract leads to topical wound healing in diabetic rats and material contained in Artemisia cause, faster wound contraction, and the healing. Manuscript profile -
Open Access Article
97 - A Novel Method for Skin Lesion Segmentation
Fatima Rashid Sheykhahmad Navid Razmjooy Mehdi Ramezani -
Open Access Article
98 - Histopathological evaluation of the effects of Intrapretoneal Isotretinoin on skin, kidney and Liver of the NMRI mouse fetus
اعظم Kalantari, رمضان Khanbabaee, B. EslamiSide effects of the drugs on the human body have always been under discussion. One of the most effective andacceptable methods of determination of drugs side effects is testing the medicines on laboratory animals. Despitethe fact that Isotretinoin is widely being used i MoreSide effects of the drugs on the human body have always been under discussion. One of the most effective andacceptable methods of determination of drugs side effects is testing the medicines on laboratory animals. Despitethe fact that Isotretinoin is widely being used in the treatment of severe refractory to treatment nodular acne,Keratinization disorder refractory to common treatments, prevention of skin cancer and especially squamous cellcarcinoma of the head and neck, the adverse effects of the drug on the body have been reported. The drug isstrongly advised not to be used by particularly pregnant women for its teratogenic effects. The side effectsof this drug depends on the duration of the treatment. For example, in humans, the recommended duration oftreatment for acne is 15 to 20 weeks and prolonged treatment often causes some side effects such as increase inserum triglycerides, abnormal moisture on the skin, adverse effects on the eye, elevated blood calcium and otherunwanted disturbances. In this study, the effects of Intrapretoneal Isotretinoin on the development of skin, kidneyand liver of mouse embryos have been examined, during pregnancy. The results showed many dose dependanthistopathological changes such as: decreasing in number of hair follicles in skin, congestion, blood vessel dilation,increasing in permeability of blood vessels in kidneys and accumulation of the bile in the liver. Manuscript profile -
Open Access Article
99 - Histopathological effects of flowering shoot hydroethanol extracts of Hypericumperforatum on experimental full-thickness skin wound healing in rats
, M AsghariehAhary M.R Farahpour,Wound healing has always been of great concern for the surgeon and therefore using different effective biologicalsubstances of either plant or animal origin for a faster and more effcient wound healing (repair) has been considered.The aim of this study was to investigat MoreWound healing has always been of great concern for the surgeon and therefore using different effective biologicalsubstances of either plant or animal origin for a faster and more effcient wound healing (repair) has been considered.The aim of this study was to investigate the accelerating effects of Hypericumperforatumhydroethanolextracton open wound healing in rats. Study design: thirty-six adult male Wistar-albino rats (weight 200±10 g) wererandomly allocated to three groups (one control and two treatment groups). Two seven-mm, circular, fullthicknesses, skin wounds were created on the back of each rat (2 on the left and 2 on the right side). In the controlgroup, wounds were treated by an ointment with no extract. The treatment groups were treated by standardizedointment containing 1% and 2% Hypericumperforatum extract. For histopathological studies, the 3 groups weresubdivided into 4 subgroups with 4 rats in each. Samples were taken from the groups 1 to 4 on days 3, 7, 14, and21, respectively. After taking the sample, the rats were euthanized. The sequential wound biopsies were evaluatedhistopathologically for their heamorrage,neutrophils and lymphocyte, new vascularization and re epithelialization.According to the results of this study, the ointment with 2% extract was much better and slightly better than thecontrol and 1% extract ointments, respectively. Manuscript profile -
Open Access Article
100 - Validity and Validity of Shame Questionnaire (MSRI-21)
Faranak ahmadi parvari zahra bordanThe aim of this study was to evaluate the validity and reliability of the Shame Questionnaire. The statistical population of the present study was the students of the Islamic Azad University of Saveh in the second semester of the academic year 1300-1389 and the statisti MoreThe aim of this study was to evaluate the validity and reliability of the Shame Questionnaire. The statistical population of the present study was the students of the Islamic Azad University of Saveh in the second semester of the academic year 1300-1389 and the statistical sample was 280 of these students who were selected by convenience sampling method and then the shame questionnaire (MSRI-21) on them. Was implemented. The questionnaire assesses shame-related responses in three categories: negative self-esteem, fear of social consequences, and tendency to maladaptive behavior. Data were analyzed using descriptive statistics, exploratory factor analysis and Cronbach's alpha. According to the research findings, this questionnaire is saturated with three factors that together explained 54.296% of the variance and has acceptable validity and reliability. The results show that MSRI-21 is a reliable and valid evaluation of the response. Is related to shame, and is successful for medical research and use. Therefore, therapists, researchers, and all counselors can use it as a valid tool to measure the variable of shame. Manuscript profile -
Open Access Article
101 - An Investigation on the Suitable Features of Double-Skin Façade in Lines with Reducing Energy Consumption in Cold and Arid Climate: A Case Study of Mashhad City
Faranak Farhadi Nasab Fatemeh Mozaffari Ghadikolaei Leila MirsaeediThis research deals with an efficient approach to achieve the optimization of energy consumption by emphasizing the selected and optimized features in the two-shell facade and in the form of a general question under the title that the application of two-shell facades in MoreThis research deals with an efficient approach to achieve the optimization of energy consumption by emphasizing the selected and optimized features in the two-shell facade and in the form of a general question under the title that the application of two-shell facades in towers How multipurpose can lead to reduction of energy consumption and thermal comfort in the cold and dry climate of Mashhad city. The crisis of energy is one of the greatest concerns that the world is facing today, especially in the area of building and architecture. Considering the limitations of determining the areas related to high-rise construction and compiling special construction rules in Mashhad city, in this dissertation, the researcher found the maximum height in the selected sample to be 150 meters with 34 floors as the first. and it is considered the tallest building in Mashhad city, in addition, according to the two tables and considering the most prominent tower in terms of being the tallest and also having the highest number of floors (on average), considering that Some of these towers are older in terms of age and have a lower height, and the towers under construction in Mashhad are on average taller than some of these towers, even though they are famous and prominent, and in addition One reason for choosing the tallest tower with the highest number of floors is that the effect of the variables investigated in this thesis increases with the increase in height, and in this thesis, solutions for the tallest towers are also supposed to be given. Accordingly, in order to investigate the function of double-skin facade and its effect in the climate of Mashhad City and to select a suitable option from amongst four types of double-skin facade, in the current study, first, four types of double-skin façade (multi-story, shaft-box, corridor, box-window) are considered in terms of energy in the climate of Mashhad City which is a cold and arid region, and the study is conducted on a multi-purpose and high-rise building in order to find the most optimal state for the region of Mashhad, and then the speed of wind and the air flow temperature in the façade shall be analyzed and the findings and conclusion of the study shall be presented The results of the study showed that the increase of the depth of middle hole leads to the improvement of the thermal function of the whole double-skin façade with an average of thermal comfort limit. Manuscript profile
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