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        1 - Evaluation of Kelussia odoratissima Mozaff. extract on serum biochemical parameters and hepatica enzymes in the Persian Shepherd dogs
        اردلان معینی سام ترکان فاطمه ملک پور
        Background & Aim:Nowadays, attention has increasingly been directed toward the treatment of animal’s disease using medicinal herbs. This research was conducted to evaluate the impact of Kelussia odoratissima Mozaff extract on dog serum biochemical parameters a More
        Background & Aim:Nowadays, attention has increasingly been directed toward the treatment of animal’s disease using medicinal herbs. This research was conducted to evaluate the impact of Kelussia odoratissima Mozaff extract on dog serum biochemical parameters and hepatica enzymes over time. Experimental: 32 adult dogs were randomly assigned to four groups. The first (control) group did not receive any pharmaceutical compound. The second group received 150 mg/kg of hydro-alcoholic extract of k.odoratissima. The third and the forth groups received 300 and 450 mg/kg of the extract, respectively. Finally, the blood samples were collected on days 0, 5, 10, and 15 for serum biochemical parameters analysis including the level of blood sugar, cholesterol, triglyceride, LDL and HDL, alanine aminotransferase, aspartate aminotransferases, and alkaline phosphatase. Results: Comparing to the control group, the levels of fast blood sugar, low density lipoprotein, high density lipoprotein, trigliceride, cholesterol, Alanin aminotransferase and aspartate aminotransferase in treated groups were significantly different over time and at various doses of the extract (P<0.05). However, the level of Alkaline-phosphatase (ALP) factor did not change throughout this study (P>0.05). Recommended applications/industries: Considering the results of this study, anti-diabetic, anti-atherosclerotic and antioxidant effects of Kelussia odoratissima can be concluded. Then, the possibility of employing K. odoratissima extract in drugs for the treatment of mentioned diseases can be suggested. Manuscript profile
      • Open Access Article

        2 - Effect of Spirulina platensis on the immunological and hematological factors in comparison with levamisole in Persian shepherd dogs
        سام ترکان محمد جواد عکاشه
        Background & Aim: Spirulina microalgae is known to has beneficial effects in the treatment of many animals diseases. Effects of Spirulina platensis microalgae, singly or in comparison with levamisole drug are not still studied in dogs. Thus, the present study was co More
        Background & Aim: Spirulina microalgae is known to has beneficial effects in the treatment of many animals diseases. Effects of Spirulina platensis microalgae, singly or in comparison with levamisole drug are not still studied in dogs. Thus, the present study was conducted to investigate the effects of this microalgae on hematological and immunological parameters in dogs.Experimental: In this research, 24 native breed dogs were used for 30 days. The dogs were divided into three groups of eight randomly, including a control group, treatment group (received 2 g Spirulina orally) and the third group received 5 mg/kg Levamisole. At the end of mentioned period, hematocrit percent, Hb, RBC, WBC, Neutrophil, Lymphocyte, Eosinophil, monocyte, basophil levels and immunological factors including IgM, total protein and phagocytic precent were measured.Results: Hematocrit in levamisole receiving group increased significantly (P<0.05). Results showed that RBC and Hb levels in Spirulina receiving group were significantly higher than the control and levamisole groups. Alb and Neutrophil levels in Spirulina receiving group were lower than the other two groups. In addition, Eosinophil and WBC levels in control group were significantly lower than the other two groups, but monocyte and Lymphocyte levels in control group increased significantly (P<0.001). Also, on the 30th day, total protein and phagocytic percent in Spirulina receiving group were significantly higher than others groups. In addition, in Spirulina and levamisole groups a significant increase in IgM level was observed (P<0.001).Recommended applications/industries: It can be concluded that the use of Spirulina in dogs for a short time could improve hematological and immunological factors and the effects of Spirulina alga in the most factors is comparable to levamisole drug. Manuscript profile
      • Open Access Article

        3 - The comparison of anti-diarrhea effects of two herbal compounds namely Elaeagnus Angustifolia (Oleaster) and Plantago major powders in Dogs
        علیرضا لطفی سام ترکان محسن جعفریان دهکردی
        Background & Aim:Increasing the tendency in families for taking care of pets makes people pay more attention to their disease especially the common ones. In recent years the tendency to use of herbal drugs has increased in animals. Herbal drugs are plants that on More
        Background & Aim:Increasing the tendency in families for taking care of pets makes people pay more attention to their disease especially the common ones. In recent years the tendency to use of herbal drugs has increased in animals. Herbal drugs are plants that one or some of their members have effective. We supposed that the Elaeagnus angustifolia(oleaster) powder has the plantagel. Therefore, the aim of this study is to compare the oleaster powder herbal compounds and plantagel as anti-diarrhea in dogs. Experimental: This study was done on 12 male dogs collar (3 quadri groups) with the similar approximate weight and similar age in veterinary clinic of Islamic azad university of Shahrekord branch. Sana flower herbal syrup was used to cause the diarrhea in all 3 groups. They received 15 mg/kg every 12 hours and all groups were suffering from diarrhea. Three groups were studied including testifier group without remedy, the first care group that received 5 mg/kg of oleaster and the second care group that received the plantagel powder every day and during this period of time the whole index related to diarrhea were exanimate whether on aspect of clinical or mortal factors. Results: By looking at the mortal indices, it was observed that the percentage of hematocrit in plantagel and oleaster groups in comparison with testifier group in recovery time was significantly different (P>0.05), that shows the recovery of mortal hematocrit index. Also the percentage of neutrophils in oleastergroup with testifier and plantagel groups was observed a meaningful difference which is reducethat is a sample of meaningful increase in comparison with other groups (P>0.05). Also by sampling from excrement, the numbers of the bacteria showed a meaningful difference in oleaster and plantagel group in comparison with testifier group (P>0.05). Recommended applications/ industries: The use of oleaster powder as dose and time dependent causes reducing the duration of diarrhea because of the prehensile materials in oleaster. Manuscript profile
      • Open Access Article

        4 - The examination of the changes in serum biochemical factors caused by the ingestion of oral Sumac in dogs
        حسن میرمحمدی سام ترکان محسن جعفریان دهکردی
        Introduction and goal: Today, the researchers have found that many recent diseases are due to cellular oxidative stress which is caused by the imbalance of the formation and neutralization of free radicals. Including weak immune system, cancers, inflectional diseases, a More
        Introduction and goal: Today, the researchers have found that many recent diseases are due to cellular oxidative stress which is caused by the imbalance of the formation and neutralization of free radicals. Including weak immune system, cancers, inflectional diseases, aging body and Diabetes. Diabetes is the most common endocrine disease in the world that is referred to as the mother of the diseases for affecting the whole body such as digestive system, kidneys, eyes and most importantly cardiovascular system (atherosclerosis) which is the main cause of death in the developed world. Materials and Method: In this research 6 local dogs were used for 10 days and divided into 3 groups of 2:the control group, the group receiving 10 mg/kg of Sumac and the group receiving 5 mg/kg of Sumac. At the end of the oral Sumac ingestion, blood samples were taken and the relevant tests were done. Results and Discussion: The results of the present research indicated that adding Sumac powder in dog feed for 10 days, significantly decreased serum glucose, triglyceride and liver enzymes Aspartate aminotransferase (AST), Alanine aminotransferase (ALT) parameters (p< 0.05). However, there was no significant differences between the cholesterol level of the examined groups during the research specified period of time (p> 0.05). Industrial / Practical recommendation: Considering that the results of the present study are consistent with similar research, anti-diabetic, anti-atherosclerotic and antioxidant effects of Sumac can be concluded. It can also be used as a replacement for chemical drugs. Manuscript profile