List of Articles

• Open Access Article
  • Abstract Page
  • Full-Text
  
  1 - Survey on quality and quantity of essential oil cultivated accessions of Thymus fedtschenkoi Ronneger in province Yazd
  عباس زارع زاده مهدی میرزا ابراهیم شریفی عاشورآبادی علی میرحسینی محمدرضا عرب‌زاده
  Background & Aim: The genus Thymus belonging to the family of lamiaceae and consist over 215 different species throughout the word. Eighteen species grow naturally in Iran of which four species are endemic. Experimental: This reseach has been carried in medicinal p More

  Background & Aim: The genus Thymus belonging to the family of lamiaceae and consist over 215 different species throughout the word. Eighteen species grow naturally in Iran of which four species are endemic. Experimental: This reseach has been carried in medicinal plants research station in Yazd province with the coordinates of longitude and latitude 55 31 49 northly, 27 15 54 east to heigh of 1209 meters above Sea level in the region Gerdefaramarz city of Yazd shahedial. In order to in 2011 year seeds 5 accession of T. fedtschenkoi collected from West Azarbayejan, Semnan and Zanjan provinces, were planted in jifypot. The aeril parts of plants were collected 50% flowering stage and then were dried in shadow and hydro– distilled for obtaining their essential oil. Analysis and identification of chemical composition of the oil were performed by GC and GC/MS. Results & Discussion: The highest amount of oil yield respectively were related to accession TF3 from Semnan (4.2%), and lowest was related to accession TF5 from West Azarbayejan(0.8%). The highest amount of oil production respectively was related to accession TF3 (32/8kg/ha) and lowest was related to TF5 (3kg/ha). Results showed that maximum compositions of essential oil Thymol, P-cymen, carvacrol, borneol, Terpineol, γ-terpinene, 1,8 cineol, E-caryophyllene and linalool, respectively TF1 (70/1%), TF5 (20/2%), TF4 (18/1%), TF4 (10/4%), TF3(4/5%), TF5 (4/1%), TF4 (3/6%), TF3 (3/3%) and TF5 (3/1%) Generally, with regard to oil yield, oil production and main composition of essential oil accession TF3 with 4/2% and rate of oil production 32/8kg/hectare and 66/3% Thymol was selected as superior accession. Recommended applications / industries: Since the accession TF3 yield, oil yield and thymol is high. for planting in the same climate zones is recommended. Manuscript profile
• Open Access Article
  • Abstract Page
  • Full-Text
  
  2 - A review on application of plant essential oils in food packaging films
  الهه امانی امیرپویا قندهاری یزدی لیلا صداقت بروجنی
  Introduction: Active packaging is one of the innovations in food packaging industry that would be a respons to the changing needs of consumers and markets. In this technique, materials such as adsorbents oxygen, moisture, carbon dioxide, ethylene and carbon dioxide-rele More

  Introduction: Active packaging is one of the innovations in food packaging industry that would be a respons to the changing needs of consumers and markets. In this technique, materials such as adsorbents oxygen, moisture, carbon dioxide, ethylene and carbon dioxide-releasing flavor compounds, antimicrobials, antioxidants and various aromatic compounds are used. In the last decade, great attention are paid to application of antimicrobial compounds for food packaging and food contact surfaces, the plant essential oils are one of the active constituents in this area. In this article, different kinds of plant essential oils, constituents, antimicrobial properties, mutagenicity and anti-mutation effect of these compounds and their use in food packaging and its impact on the physicochemical properties of packaging and food packaging are discussed. Results: Plant essential oils and its compounds such as linalool, thymol, cinnamaldehyde, vanillin, carvacrol, and many other compounds because of their characteristics such as anti-microbial, anti-fungal and anti-oxidant activity are acceptable for using in the food industry and increasing shelf life of corruptible materials. Nowadays, many studies have shown that most of these substances are not harmful to human health; therefore, has found considerable acceptability in industry and among consumers. Conclusion: Antimicrobial packaging is a type of active packaging that is effective on shelf life, health and food safety. Various materials such as plant essential oils are used in this type of packaging which increase the shelf life and product quality. However, the safety of these compounds before using in industry must be determined. Manuscript profile
• Open Access Article
  • Abstract Page
  • Full-Text
  
  3 - Compare the effect of ginger extract and aspirin on COX-2 gene expression in colon cancer cell line HT-29
  آرزو حقیقی نوشا ضیا جهرمی
  Background and aim: Colon cancer is the third most prevalent cancer in Iran. Prolonged colon inflammation is an important factor, in the development of colon cancer. Ginger has anti-inflammatory properties due to its content of [6]-gingerol and hence can play a role in More

  Background and aim: Colon cancer is the third most prevalent cancer in Iran. Prolonged colon inflammation is an important factor, in the development of colon cancer. Ginger has anti-inflammatory properties due to its content of [6]-gingerol and hence can play a role in the prevention of colon cancer. In this research the effects of ginger extract on reducing expression of the Cox-2 gene in HT-29 cells was studied in colon cancer. Methodology: In this laboratory research, HT-29 cells of colon cancer were and the cells were trypsinated at the third passage and 5000 of them were cultured in the wells of 96-well plates. Ginger extract at four concentrations (10, 20, 30, and 40 mg/mL) was added to the wells, and the plates were incubated at 37˚C for 24, 48, and 72 hours in a 5% Co2 atmosphere. To study the effects of ginger extract on the cells, the MTT test was performed and the densities of the plates were read using an ELISA instrument. Total cellular RNA was extracted and expression of the COX-2 gene was investigated using the RT-PCR method. Results and Discussion: The measured IC50 concentration of the ginger extract was 20 mg/ml. Determination of the expression of the COX-2 gene using the RT-PCR method indicated that the ginger extract at 20 mg/ml reduced expression of the COX-2 gene compared to using Aspirin. Therefore, ginger extract could be used as an anti-inflammatory drug against the HT-29 cells of colon cancer. Reduction of inflammation is important in patients with colon cancer, and results of this research indicated use of ginger extract could play an important role in decreasing inflammation and in reducing the expression of the COX-2 gene, which has a significant role in the synthesis of prostaglandins and in causing inflammation. Manuscript profile
• Open Access Article
  • Abstract Page
  • Full-Text
  
  4 - The effect of climatic conditions on the concentration of stevioside in Stevia production in different regions of Iran and optimization of stevioside extraction
  آلاله نیکوئی محمد حجت الاسلامی جواد کرامت حسین کیانی
  Background & Aim: According to the increase in diseases such as diabetes and obesity, using of saccharose alternatives for producing of low-calorie and sugar-free alternatives, are taken into consideration of researchers and industrialists. Among them, steviosidewit More

  Background & Aim: According to the increase in diseases such as diabetes and obesity, using of saccharose alternatives for producing of low-calorie and sugar-free alternatives, are taken into consideration of researchers and industrialists. Among them, steviosidewith the 300 times more sweetness than saccharose has special place, due to is a natural. The aim of this study is optimizing of stevioside extraction conditions from leaves of stevia (the solvent, temperature and time) and evaluation the effect of different climates on the stevioside concentration. Experimental: At first, optimizing extraction of stevioside (the solvent, temperature and time) was done. Then, obtained results on the plants in five regions with different climates (Tehran: dry and semi-dry, Kashan: warm and dryIsfahan: temperate and mountainous, Shahrekord : cold and mountainous Shiraz: warm and mountainous) was applied, and finally concentration steviosidewas investigated using high performance liquid chromatography. Results and discussion: According to the results, the best extraction conditions is at the time of 120 minutes, 50 ° C and 160 ml of solvent (ethanol). After that, by applying the results on the cultured plants in five cities: Tehran, Isfahan and Shiraz, Kashan and Shahrekord, results showed climate conditions have effect on product. So that, among them, the cultured plants in Isfahan have the highest level of production efficiency (tons per hectare); although, have the most impurities. Recommended applications/industries: According to rise in consumtion of stevioside sweetener and increase in price of mentioned sweetener, its cultivation is very important in Iran. The survey results indicate that application of it in country can be achieved by solvent. However, more research on the other extraction methods is necessary and important. Manuscript profile
• Open Access Article
  • Abstract Page
  • Full-Text
  
  5 - Hypoglycemic, and hypolipidemic effect of Smyrnium cordifolium Boiss extract in streptozotocin induced diabetic male rats
  فرشته شهرام فر لیلا روحی خدیجه روستایی
  مقدمه و هدف: دیابت یکی از شایع ترین بیماری های قرن حاضر است. در این پژوهش تاثیر عصاره هیدروالکلی گیاه آوندول بر رت‌های دیابتی مورد بررسی قرار گرفت. روش تحقیق:در این مطالعه تجربی، ۴۰ سر رت نژاد ویستار به طور تصادفی به 5 گروه یکسان تقسیم شدند. گروه 1 (کنترل سالم): رت‌هایی More

  مقدمه و هدف: دیابت یکی از شایع ترین بیماری های قرن حاضر است. در این پژوهش تاثیر عصاره هیدروالکلی گیاه آوندول بر رت‌های دیابتی مورد بررسی قرار گرفت. روش تحقیق:در این مطالعه تجربی، ۴۰ سر رت نژاد ویستار به طور تصادفی به 5 گروه یکسان تقسیم شدند. گروه 1 (کنترل سالم): رت‌هایی سالم و غیر دیابتی که در شرایط نوری، آب و غذای یکسان با سایر گروه ها نگهداری شدند. گروه 2 (کنترل دیابتی) رت‌هایی که استرپتوزوتوستین با دوز 6/0 mg/kg به صورت داخل صفاقی دریافت کردند. گروه 3 (گروه دارو) رت‌‌هایی دیابتی که روزانه 5/0 سی‌سی گلی‌بنکلامید با دوز 6/0 mg/kgوزن بدن را به صورت گاواژ دریافت کردند. گروه 4 و 5 (گروه تیمار ۱ و ۲) رت‌هایی که روزانه 5/0 سی‌سی از عصاره هیدروالکلی برگ گیاه آوندول با دوزهای 200 و 400mg/kgوزن بدن را به صورت گاواژ دریافت کردند. در پایان تیمار 28 روزه، از قلب همه رت‌ها خون گرفته شد و سطح گلوکز به روش آنزیمی و کلسترول و تری‌گلیسیرید با کیت‌های شرکت پارس آزمون به روش اسپکتروفتومتری تعیین شد. نتایج و بحث: این مطالعه نشان داد که فاکتورهای گلوکز، تری گلیسیرید و کلسترول در نتیجه تیمار با عصاره هیدروالکلی برگ گیاه آوندول (Smyrnium cordifolium Boiss) به طور معنی داری کاهش یافت (P<0.05). توصیه کاربردی/صنعتی: این گیاه با داشتن اثرات هیپوگلیسمیک و هیپولیپیدمیک و به دلیل عوارض جانبی کم‌تر، در مقایسه با داروهای شیمیایی، در درمان دیابت توصیه می‌شود. Manuscript profile
• Open Access Article
  • Abstract Page
  • Full-Text
  
  6 - The examination of the changes in serum biochemical factors caused by the ingestion of oral Sumac in dogs
  حسن میرمحمدی سام ترکان محسن جعفریان دهکردی
  Introduction and goal: Today, the researchers have found that many recent diseases are due to cellular oxidative stress which is caused by the imbalance of the formation and neutralization of free radicals. Including weak immune system, cancers, inflectional diseases, a More

  Introduction and goal: Today, the researchers have found that many recent diseases are due to cellular oxidative stress which is caused by the imbalance of the formation and neutralization of free radicals. Including weak immune system, cancers, inflectional diseases, aging body and Diabetes. Diabetes is the most common endocrine disease in the world that is referred to as the mother of the diseases for affecting the whole body such as digestive system, kidneys, eyes and most importantly cardiovascular system (atherosclerosis) which is the main cause of death in the developed world. Materials and Method: In this research 6 local dogs were used for 10 days and divided into 3 groups of 2:the control group, the group receiving 10 mg/kg of Sumac and the group receiving 5 mg/kg of Sumac. At the end of the oral Sumac ingestion, blood samples were taken and the relevant tests were done. Results and Discussion: The results of the present research indicated that adding Sumac powder in dog feed for 10 days, significantly decreased serum glucose, triglyceride and liver enzymes Aspartate aminotransferase (AST), Alanine aminotransferase (ALT) parameters (p< 0.05). However, there was no significant differences between the cholesterol level of the examined groups during the research specified period of time (p> 0.05). Industrial / Practical recommendation: Considering that the results of the present study are consistent with similar research, anti-diabetic, anti-atherosclerotic and antioxidant effects of Sumac can be concluded. It can also be used as a replacement for chemical drugs. Manuscript profile
• Open Access Article
  • Abstract Page
  • Full-Text
  
  7 - The effect of using of bitter cucumber fruit powder, Citrullus colocynthis, and probiotic on growth performance and intestinal morphology of broiler chicks
  مجید هاشمی سید محمدعلی جلالی فرشید خیری
  Background & aim: The fruit of Citrullus colocynthis has a bitter taste and antibacterial properties against pathogen factors.The aim of current research was to study the effects of different dietary level of bitter cucumber fruit powderwith and without protexin pro More

  Background & aim: The fruit of Citrullus colocynthis has a bitter taste and antibacterial properties against pathogen factors.The aim of current research was to study the effects of different dietary level of bitter cucumber fruit powderwith and without protexin probiotic supplementation on growth performance, carcass traits and intestinal morphology of broiler chicks. Experimental: Two hundred forty of one-days old of Ross broiler chicks at a 4×2 factorial experiment design (0, 0.2, 0.4 and 0.6%bitter cucumber with 0 and 0.01%protexin) were randomly distributed to eight dietary treatments with three replicates and fed 42 days. Feed intake, body weight gain and feed conversion ratio of birds were measured during the experiment. At the end of experiment the internal organs of chicks were weight and intestinal morphology was evaluated. Results: Feed intake of chicks significantly reduced by 0.4 and 0.6% bitter cucumber fruit treatments and body weight gain of chicks were significantly improved (p<0.05). Feed conversion ratio significantly reduced in bitter cucumber fruit powder treatments (p<0.05) but probiotic supplement didn’t show any effect on this parameter. The bitter cucumber fruit powder significantly increased the yield of carcass, breast meat and heart of chicks. The villus height, width, crypt depth, and thickness of muscle mucosal of intestinal chicks were significantly increased by 0.6% bitter cucumber dietary treatment and probiotic supplement significantly increased villus height and thickness of muscle mucosal of chicks (p<0.05). Recommended applications/industries: The results of this experiment showed that dietary supplementation of bitter cucumber fruit powder at 0.4% with protexin probiotics could be used as a symbiotic supplement in diets of broiler chicks. Manuscript profile
• Open Access Article
  • Abstract Page
  • Full-Text
  
  8 - Quantitative and qualitative changes of essential oil of Artemisia haussckenechtii in different phenological stages
  حمزه امیری مسعود گودرزی
  Background & Aim: Artemisia species with common Persian name of Dermaneh are found all over Iran and are used for treatment in infectious diseases such as malaria, hepatitis and other diseases. Some Artemisia species are used in traditionally as tonic and anti-helmi More

  Background & Aim: Artemisia species with common Persian name of Dermaneh are found all over Iran and are used for treatment in infectious diseases such as malaria, hepatitis and other diseases. Some Artemisia species are used in traditionally as tonic and anti-helmintic in north of Iran. Artemisia haussknechtii is used in dyspepsia and other gastrointestinal disorders by local people in the western part of Iran. Experimental: The plant materials were collected from Chamashk in South of Khoramabad in Lorestan province at three stages including before flowering, full flowering and post flowering stages and subjected to hydrodistillation using a Cleavenger type apparatus for 2 h. Results & Discussion: The results showed that yields of essential oil were 1.2%, 2.5% and 1.6% w/w before flowering, full flowering and fruiting stages, respectively. Thirty three, sixteen and twenty nine compounds were identified in oils before flowering, full flowering and post flowering stages, respectively. Camphor, 1,8-cineol and cis-Davanone and limonene were the main components of essential oil of different growth stages. Also camphor as the main constituent was obtained from flowering stage Recommended applications/industries: Camphor as the main component of essential oil has shown health benefits as a stimulant, antispasmodic, antiseptic, decongestant, anesthetic, sedative, anti-inflammatory, and insecticide substance. Manuscript profile
• Open Access Article
  • Abstract Page
  • Full-Text
  
  9 - Anti bacterial effect , extent of phenol compound, and anti oxidant operate of alcoholic essence of Allium hirtifolium Boiss
  الهه آل ابراهیم دهکردی عبدالله قاسمی پیربلوطی محمود رفیعیان کوپایی
  Introduction: Shallot is a plant which belongs to Alium and Albale family , this is a native plant from Iran which is self – grown in high Zones. By regard to further use of medicine and plant’s product , use of herbal plants has on important nole in medical More

  Introduction: Shallot is a plant which belongs to Alium and Albale family , this is a native plant from Iran which is self – grown in high Zones. By regard to further use of medicine and plant’s product , use of herbal plants has on important nole in medical treatment and preventi of diseale. The purpose of this study is the photo chemistry properties and anti – bacterial effects of this plant. Method and research : In this study we prepared plant’s essence by use of maceration method and specify the extent of phenol and compound by use of folin eiocalteu and Aluminium V method . In order to effect , the DPPH method and in onder to investigate anti – bacterial effect , the method has been used . Analysis of data u(a) done by use of SPSS & dnausing the graphs was done by Excel. Results and discussion : The most amount of phenol and compound in each gnam of dried essence is : 13/5, 0/77 , 9/59 . Moneouer , anti – bacterial results showed that of shallot’s leaf and onion has acceptable fatal and disincentive effects on staphylococcus accrues and Ancinetobacter baumanni The lowest fatal concentatti on staphylococcus bacteria has been observed has been observed in 1280micrognam / ml. Practicable and industrial advices : The results show that Allium hartifolium Boiss has anti – oxidant effect and it’s leaf has more phenol compounds in nelatti to the onion and can disincentive the DDPH free ladical . Also shallot’s leaf and onion has anti – bacterial effect and can be use as anti – bacterial compound. Manuscript profile
• Open Access Article
  • Abstract Page
  • Full-Text
  
  10 - Phytochemical characteristics variation of different populations of Tanacetum parthenium cultivated in Shahrekord climatic
  راضیه عبدالهی ارجنکی
  Background and aim: Tanacetum parthenium L. is herbaceous perennial medicinal plant belonging to the Asteraceae family. Feverfew is used as an analgesic, housing, fever-lowering, anti-rheumatism and migraines in traditional medicine. The most important active ingredient More

  Background and aim: Tanacetum parthenium L. is herbaceous perennial medicinal plant belonging to the Asteraceae family. Feverfew is used as an analgesic, housing, fever-lowering, anti-rheumatism and migraines in traditional medicine. The most important active ingredient of the herb is essential oil. Variation on genetic and environmental conditions play a major role in the growth, development, quality and quantity of active ingredients of medicinal plants, so this study was conducted to evaluate the diversity of phytochemical characteristics of eight different populations of Tanacetum parthenium at 2014 in Shahrekord region, southwestern Iran. Material and methods: In this study, Tanacetum parthenium seeds were collected from eight regions of Iran. After preparing the seedlings in greenhouses at Research Center in Islamic Azad University of Shahrekord, the plantlets were transferred to the field of University in early April 2014. Aerial part of the plants were harvested at two stages (50% and 100%) of flowering. Hydro-distillated essential oils were analyzed by GC and GC/MS. Results & Discussion: The highest essential oil yield was obtained from the Gilan population at 100% flowering and the lowest essential oil yield was obtained from the Ziarat population at 50% flowering. The results showed that the major compounds were camphor and bornyl acetate and the highest percentage of camphor was identified in the Shahrood population with 49.05% at fifty stage of flowering. Recommended applications / industries: According to essential oil yield and composition (especially comphor and bornyl acetate content) results indicated that two populations of Gilan and Shahrood are suitable to cultivate at Shahrekord climate. Manuscript profile