List of Articles

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  1 - Identification of phytochemicals, plant compounds Smirnovia iranica.
  منصوره قوام حسین آذرنیوند مریم اخباری
  Background & Aim: Fabaceae plant family cow tail (Smirnovia iranica) is one of the valuable species of native shrubs and sand dunes in the central region of Iran which is consistent with the production of forage and soil conservation and creating a beautiful landsca More

  Background & Aim: Fabaceae plant family cow tail (Smirnovia iranica) is one of the valuable species of native shrubs and sand dunes in the central region of Iran which is consistent with the production of forage and soil conservation and creating a beautiful landscape; it has the active ingredients of medicinal values. The purpose of this study was to investigate the presence of some phytochemicals in this plant for the first time. Experimental: The habitat of the plant, located in Kashan sand dunes four study sites were chosen from a distance of 30 km. Phytochemical study during the third week of April 1391 flowering branches and leaves collected at each site using soxhlet apparatus for 8 h were extracted by methanol extract of leaves and flowers. Mayer and Wagner's reagent for alkaloids detected the test for determining anthocyanins and flavonoids cyanidin, Chloroferric solution to test for the presence of tannins and test the reaction of anthraquinone Bourne - Tragr was used. Results & Discussion: The results indicate the presence of alkaloids, flavonoids, anthocyanins and tannins, and the presence or absence of low- anthraquinone in both the body and the whole site. The final conclusion in terms of the priority phytochemicals valuable plant in flower organs and the optimum harvest Qasim Abad is the preferred site. Recommended applications/industries: Based on the results of this study , this native plant have worth phytochemicals that preservation and resuscitation and Advantage of its be considered Manuscript profile
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  2 - The effect of Kardeh (Biarum Bovei) Hydro-alcoholic extract on pain threshold in STZ induced diabetic rats
  معصومه سیفی زنگنه مریم رفیعی راد حسین سازگار
  Background & Aim: Diabetes mellitus in long-term through various means such as augmented oxidative stress is associated with disturbances such as pain and cognition in humans and laboratory animals. According to the evidence of anti-diabetic extract of Biarum Bovei More

  Background & Aim: Diabetes mellitus in long-term through various means such as augmented oxidative stress is associated with disturbances such as pain and cognition in humans and laboratory animals. According to the evidence of anti-diabetic extract of Biarum Bovei (BB), Effect of oral administration of this extract was evaluated on blood glucose level and pain threshold in diabetic rats. Experimental: Animals were divided into; Control (intact), diabetic (STZ 70 mg /kg) and diabetic group that received Biarum Bovei Extract (BBE) (50, 100, 200, 400, 800 mg/kg) for two weeks by gavage. Blood glucose was measured from tail blood, then performed tail filick test to measure pain threshold. The results were analyzed statistically through SPSS, One way ANOVA and Tukey's test. Diabetes led to a decrease in blood glucose (p < 0.001) and pain threshold (p <0.001) prescribed doses (100, 200 mg/kg) BBE resulted a decrease in blood glucose (p Results & Discussion: The findings of this study showed that Hydro-alcoholic extract of kadeh (BB) possibly with high-antioxidant property is able to reduce blood glucose and diabetes complications such as pain in animals. Recommended applications/industries: Considering the low side effects of herbal medicines, especially antioxidants including Kardeh can be used to reduce the complications of diabetes with drug therapy. Manuscript profile
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  3 - بررسی اثر خشک کردن بر استخراج اینولین از کاسنی ریشه ای (Cichuriumintybus L.)
  حمیده وکیلی محمد حجت الاسلامی
  مقدمه و هدف: اینولین یک پلی ساکارید ذخیره ای از دسته فروکتون ها با خواص تغذیه‌ای و تکنولوژیکی منحصر بفردی است و ریشه کاسنی ریشه‌ای (چیکوری) حاوی اینولین با زنجیرهای بلند و پایدار بعنوان تنها منبع ریشه ای برای تولید صنعتی اینولین می‌باشد. هدف از این تحقیق بررسی مقایسه مق More

  مقدمه و هدف: اینولین یک پلی ساکارید ذخیره ای از دسته فروکتون ها با خواص تغذیه‌ای و تکنولوژیکی منحصر بفردی است و ریشه کاسنی ریشه‌ای (چیکوری) حاوی اینولین با زنجیرهای بلند و پایدار بعنوان تنها منبع ریشه ای برای تولید صنعتی اینولین می‌باشد. هدف از این تحقیق بررسی مقایسه مقدار و زمان استخراج بیشینه اینولین و رنگ عصاره استخراجی از ریشه چیکوری تازه و خشک در طول زمان استخراج می‌باشد. روش تحقیق: ریشه چیکوری کاشته شده در مجتمع کشت و صنعت قزوین برداشت و برای استخراج عصاره از روش دیفوزیون و نسبت آب به خلال ۵ به ۱ و دمای ۶۰ درجه سانتیگراد و pHبرابر با ۵ استفاده شد. خشک کردن خلال ها در آون سیرکوله دار ودمای ۷۰ درجه سانتیگراد انجام گرفت. برای اندازه گیری اینولین از دستگاه HPLC و برای اندازه گیری رنگ عصاره از دستگاه رنگ سنج در طول موج ۴۲۰ نانومتر استفاده گردید. نتایج و بحث: بیشترین مقدار اینولین برای خلال تازه در زمان ۶۰ و درمورد خلال خشک در زمان ۱۱۰ دقیقه استخراج گردید. اگرچه خشک کردن به طور معنی دار باعث کاهش در میزان اینولین در ریشه چیکوری نمی‌شود اما به طور چشمگیر باعث افزایش زمان استخراج تا ۲ برابر میگردد.همینطورخشک کردن به طور معنادار باعث کاهش رنگ عصاره استخراج شده از خلال چیکوری می‌شود که بدلیل اثر آنزیم بری در حین فرایند خشک کردن می‌باشد. توصیه کاربردی/صنعتی: با توجه به محدود بودن زمان برداشت گیاه و در عین حال محدودیت ظرفیت کارخانه جهت استخراج، خشک کردن روش مناسبی جهت نگهداری ریشه ها برای استفاده در فصول دیگر سال می‌باشد بدون اینکه اثر نامطلوبی بر راندمان استخراج داشته باشد و همچنین خشک کردن ریشه ها در محل کاشت، باعث کاهش حجم ریشه و کاهش هزینه حمل و نقل آن به کارخانه می‌گردد. Manuscript profile
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  4 - Effect of Hydro-alcoholic Extract of Punica Granatum L. Peel on Ethylene Glycol-Induced Kidney Calculi in Wistar Rats
  مصطفی مرتضوی لیلا روحی
  Background & Aim: This study evaluated prevention effect of hydro-alcoholic extract of punica granatum Peel ethylene glycol-induced Nephrolithiasis in wistar rats. Experimental: 20 male Wistar rats were randomly divided into 4 equal groups. Group I animals served a More

  Background & Aim: This study evaluated prevention effect of hydro-alcoholic extract of punica granatum Peel ethylene glycol-induced Nephrolithiasis in wistar rats. Experimental: 20 male Wistar rats were randomly divided into 4 equal groups. Group I animals served as normal control (A) and received distilled water for 28 days. Group II to IV animals received 1% v/v ethylene glycol (EG) in distilled water for 28 days. Group II served as EG or negative control (B). Group III and IV (preventive groups) received hydro-alcoholic extract of punica granatum Peel orally for 28 days in dose of 200 mg/kg (C) and 400 mg/kg (D) respectively. 24-hour urine samples were collected on day 0 and 28. Urine volume and urine parameters levels (oxalate, calcium and citrate) were measured. On day 28, blood was collected for biochemical parameters (craetinine, urea and uric acid). Animals were sacrificed and kidneys were harvested, histopathologically evaluated for calcium oxalate (CaOx) crystals. Results & Discussion: EG significantly increased urine oxalate and calcium, serum creatinine, urea and uric acid levels. It also significantly decreased urine citrate level. In C and D group resulted in lower levels of urine oxalate, calcium and serum creatinine, urea and uric acid as compared to Group II. Also resulted in significantly higher levels citrate as compared to Group II (P<0.05). Industrial and practical recommendations: hydro-alcoholic extract of punica granatum peel is effective in prevention of EG- induced nephrolithiasis in Wistar rats. Manuscript profile
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  5 - Evaluation of two methods of manual and mechanized harvesting Echium Amoenum L. and determine the most appropriate method of harvesting
  عادل رنجی حمید آقا گل زاده محدثه پورعلی اشکلک محمد مهدی امیری خوریه
  Borage herbs, wild herbs and is one year with significant economic value are highly regarded local market Due to the high economic value of borage any study to improve the quality of harvest and increase product seems necessary, Two Rahim Abad (GILAN) district in the pr More

  Borage herbs, wild herbs and is one year with significant economic value are highly regarded local market Due to the high economic value of borage any study to improve the quality of harvest and increase product seems necessary, Two Rahim Abad (GILAN) district in the province Eshkourat the highest level of production as the location of choice, and studies of the factors in determining the best way to harvest borage done, Location and climatic characteristics and parameters measured included plant height, height of flower, plant spacing, colors, flowers, field capacity, accuracy and speed in manual and mechanized methods of harvesting and harvesting costs; The results showed that both the mean density of seven plants per square meter, the average plant height and total height of the match between 9/476 mm and 2/15 mm, respectively measurements; Hand-picked farm capacity in approximately 1/0 kg borage varies in time and is expected to field capacity in mechanized harvesting between 3/0 to 4/0 kg per hour borage Influenced by the density of field capacity, operator skill, the roughness of the area and is Cost per kilogram to about 800 thousand riyals borage manual method and automated method are predicted to be between 300 and 400 thousand riyals; The results indicate that the accuracy and speed of harvest mechanization methods than Manual method is higher, according to the results of the study can be stated that mechanized methods, More appropriately than in the style of hand-picked harvest borage and development of mechanized harvesting methods to increase the acreage of crop production. Manuscript profile
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  6 - Dose-dependent effects of Gundelia Tournefortii root extract on meiosis resumption and in vitro maturation in mouse immature oocytes
  مرضیه خدابنده لیلا روحی عبدالله قاسمی پیربلوطی
  Background & Aim: Oocytes in vitro maturation is an enormously promising technology for the treatment of infertility, yet its clinical application remains limited owing to poor success rates. Therefore this study was designed to determine the effect of Gundelia Tour More

  Background & Aim: Oocytes in vitro maturation is an enormously promising technology for the treatment of infertility, yet its clinical application remains limited owing to poor success rates. Therefore this study was designed to determine the effect of Gundelia Tournefortii root hydro alcoholic extract as a source of antioxidant on in vitro oocyte maturation. Experimental: In this study, the immature oocytes nucleated were obtained from NMRI mice (6-8 weeks). Germinal vesicles (GV) were cultured for 24 hours in maturation medium in MEMα supplemented with 7.5IU/ml hCG, 100mIU/ml rhFSH, 5% FCS (control group) and adding 10µg/ml Gundelia Tournefortii extract (group 1), 20µg/ml Gundelia Tournefortii extract (group 2) and 40µg/ml Gundelia Tournefortii extract (group 3). Then in vitro maturation stages and resumption of meiotic in all groups was recorded by inverted microscope. Results & Discussion: In group 1 that the oocytes were exposed 10µg/ml of Gundelia Tournefortiiroot extract,maturation rates was significantly higher compared with the control group (p<0/05). In group 2, the oocytes were exposed 20µg/ml of Gundelia Tournefortiirootextract, maturation rates showed a significant increase compared to the control group (p<0/05). In group 3 the oocytes were exposed 40 µg/ml of Gundelia Tournefortiirootextract, also maturation rates showed a significant increase compared to the control group (p<0/05). Industrial and practical recommendations: The results of this study showed that the Gundelia Tournefortiirootextract, has a positive doses dependent effect on oocyte maturation. So with increasing concentration of Gundelia Tournefortiirootextract, the rate of maturation immature oocytes is increased. Manuscript profile
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  7 - Gastroprotective effects of Thymus daenensis hydroalcoholic extract against ethanol-induced gastric mucosal ulcers in rats
  فیروزه سقایی محمد صالحی محمد جواد نمازی محمد باقری
  Background & Aim: Ulcer index is one of the most common diseases among people. Current therapies include acid secretion inhibitors which have various side effects. Herbal medicines are considered as adjuvant therapy for this disease. Hydroalcoholic extract of Thymus More

  Background & Aim: Ulcer index is one of the most common diseases among people. Current therapies include acid secretion inhibitors which have various side effects. Herbal medicines are considered as adjuvant therapy for this disease. Hydroalcoholic extract of Thymus daenensis has various components such as flavonoids which contribute to gastroprotection. Experimental: 35 Sprague Dawley rats (200-250 g weight) were randomly divided into 7 groups: Group 1 received salin, Groups 2 and 3 and 4 (experimental groups) received ethanolic extract of Thymus daenensis (500 and 1000 and 1500 mg/kg respectively), Group 5 received omeprazole 20 mg/kg., Group 6 received orally carboxy methyl cellulose (omeprazol vehicle), Group 7(negative control) received saline. One hour later absolute ethanol was given orally to all rats except group 7 to induce gastric mucosal injury. After 4 hrs. the rats were anesthetized and sacrificed. Blood samples were collected through heart and were administrated to SOD measurement and gastric tissues were removed for histopathologic study and MDA assessment. Results & Discussion: The extract of plant was a significant and dose dependent effect to reduce ulcer index and to increase the percentage of ulcer inhibition. The study also indicated a significant increase in SOD activity in serum, whereas a significant decrease in MDA was observed. The ulcer protective effect of this plant may possibly be due to antioxidant effects and reduction of oxidative stress. Manuscript profile
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  8 - Variation in yield and yield components in cultivated accessions of Satureja macrantha in Yazd
  عباس زارع زاده فاطمه سفیدکن سیدرضا طبایی عقدایی علی میرحسینی محمدرضا عرب‌زاده
  Background & Aim: The genus Satureja belonging to the family of lamiaceae and consists of over 235 different species throughout the world. Fourteen species grow naturally in IRAN of which eleven species are endemic. Different species of Satureja are used in food, He More

  Background & Aim: The genus Satureja belonging to the family of lamiaceae and consists of over 235 different species throughout the world. Fourteen species grow naturally in IRAN of which eleven species are endemic. Different species of Satureja are used in food, Healthy, cosmetic and medical industry. This reseach has been carried due to selection and introduction of suitable germplasm in Satureja macrantha accessions. Experimental: This reseach has been carried in medicinal plants research station inYazd province with the coordinates of longitude and latitude 55 31 49 northly, 27 15 54 east to a heigh of 1209 meters above Sea level in the region Gerdefaramarz city of Yazd shahedial. In order to in the first year seeds 3 accession of Satureja macrantha obtained from the research institute of forsts and Rangelands, were planted in jifypot and in the green house. Then seedling in case of randomized complete block with three replication were planted on the main floor. Rate of plant establishment, canopy diameter, plant height, yield, essential oil yield per hectare, percentage of essential oil, were meseared and recorded. Results & Discussion:The results showed, analysis of variance rate of plant establishment at the level of one percent was significant and plant heigh, canopy diameter, yield, essential oil yield per hectare, percentage of essential oil, dry weight of shoot and leaf, were not significant. Regarding to yield, percentage of essential oil, essential oil yield per hectare and amount plant stablishment accessions SM1 with mean of yield(2410 kg/ha), percentage of essential oil(1.03%), oil yield(15.8kg/ha) and amount plant stablishment(42.7%) with origin East Azarbayejan province was selected superior accessions. Recommended applications / industries: Because of that in Satureja macrantha is essential oil and high yield. for planting in the same climate zones is recommended. Manuscript profile