XML
-
-
List of Articles
-
Open Access Article
1 - Comparative Study of Chemical Composition and Antioxidant Activity of Essential Oil Extracted from Acorus calamus L. Leaves
پینکی چابی آرکانا پارکی ام پراکاش راوندرا کومار ای. کا پانتBackground & Aim: Acorus calamus L. is a native herb in India. The herb belongs to family Acoraceae. It is perennial and grows in marshy land with scented rhizomes and tapered reed like leaves with 80-100 cm in height. The leaves generally arise from the rhizomes. I MoreBackground & Aim: Acorus calamus L. is a native herb in India. The herb belongs to family Acoraceae. It is perennial and grows in marshy land with scented rhizomes and tapered reed like leaves with 80-100 cm in height. The leaves generally arise from the rhizomes. It is also known as sweet flag in English and vernacularly as Bach. The present investigation reveals the chemical diversity and antioxidant activity of Acorus calamus leaf essential oils from different altitudinal regions of Uttarakhand. Experimental: The essential oil composition of Acorus calamus (Araceae) leaves, collected from twenty different ecological niches of Uttarakhand, in India with oil yield ranged between 0.2-1.4 percent, were analyzed by GC/MS. DPPH assay were performed for determination of antioxidant activity of each oil. Results: The major component ranging 43.4-60.7% of the total oil was identified as β- asarone. The other predominant constituents were α-asarone (2.6-7.9%), shyobunone (3.4-6.3%) and Z- isoelemicin (3.2-5.4%). The antioxidant activity of essential oil was studied by their ability to scavenge free radicals with different IC50 values (10.79-106.44 μg/ml) in comparison to standard antioxidant. Recommended applications/industries: The vast chemical diversity of the herb essential oil and its antioxidant potential can be good natural source for herbal neutraceuticals and phenyl propanoids, the biologically important class of terpenoids. Manuscript profile -
Open Access Article
2 - Chemical Composition and Bioactivity of the Essential Oil of Melissa officinalis L., Cultivated in Southwestern, Iran
هاله محمدپور عبدالله قاسمی پیربلوطی فاطمه ملک پور بهزاد حامدیBackground & Aim: Melissa officinalis L. (lemon balm) a valuable medicinal plant in herbal medicine is native to the eastern Mediterranean region and western Asia. It is a traditional herbal medicine, which enjoys contemporary usage as a mild sedative, spasmolytic a MoreBackground & Aim: Melissa officinalis L. (lemon balm) a valuable medicinal plant in herbal medicine is native to the eastern Mediterranean region and western Asia. It is a traditional herbal medicine, which enjoys contemporary usage as a mild sedative, spasmolytic and antibacterial agent. The objective of this study was to assess the effects of climate on quality and quantity of the essential oil of M. officinalis at Shahrekord climate, southwestern (Iran) and evaluate the antioxidant activity of the oil. Experimental: Plants were cultivated during 22-25th March 2016 in the greenhouse and transferred to the main site after three months (May), and finally harvested at the full flowering stage during August.Dried plant material (100 g) was powdered and subjected to hydro–distillation for three hours using a Clevenger–type apparatus. The hydrodistillated essential oil analyzed by GC-FID and GC/MS. The antioxidant activity was determined by using DPPH method. Results: Results indicated that the major essential oil constituents of M.officinalis L. were β-caryophyllene (23.06%), E-citral (17.61%), Z-citral (13.64%), and caryophyllene oxide (10.83%). The antioxidant activityof the essential oil showed moderate antioxidant activity (IC50=749.60 µg/g), that was lower compared to butylated hydroxytoluene (BHT). Recommended applications/industries: This potential applicability can be used as antioxidant agents for food and pharmaceutical industries. Manuscript profile -
Open Access Article
3 - Hepatoprotective Properties of Ethanol Seed Extract of Citrus paradisi Macfad (Grape Fruit) Against Paracetamol-Induced Hepatotoxicity in Wistar Rats
گادویل جی اودوم اومونیی کا یمیتان امم ای اومو اچ. او. سی ماگوو اکمینی ای یوکپه پول اس. توماسBackground & Aim: The human body has the liver as one of its largest organs. It serves as the major site for metabolism and excretion. Injury to the liver or impairment of its functions may complicate one’s health and therefore, constitutes one of the serious MoreBackground & Aim: The human body has the liver as one of its largest organs. It serves as the major site for metabolism and excretion. Injury to the liver or impairment of its functions may complicate one’s health and therefore, constitutes one of the serious public health challenges. The ethanol seed extract of Citrus paradisi Macfad (CPE) was carried out to evaluate its protective usefulness on the liver against paracematol-induced liver injury. Experimental: Thirty adult male Wistar rats were randomly allotted to five groups (6/group) and orally-treated daily with 100 mg/kg body weight of silymarin (positive Control), 10 ml/kg body weight of distilled water (negative control) and CPE (200, 400 and 600 mg/kg) body weight, respectively for 7 days. On the eighth day, all groups were administered 2 g/kg body weight of paracetamol. 24 h thereafter, animals were sacrificed under diethyl ether anesthesia and blood samples were collected by cardiac puncture for biochemical and haematological investigations. Results: Compared to the negative control, extract (200 – 600 mg/kg) significantly (p<0.05)reduced the activities of ALP, ALT and AST dose-dependently. Extract significantly (p<0.05) elevated all blood parameters except for neutrophil differentials. Recommended applications/industries: Grapefruit seed extract possesses hepatoprotective potential and can be used as an antidote against paracetamol-induced hepatotoxicity. Manuscript profile -
Open Access Article
4 - Antidepressant activity of methanol stem bark extract of Ficus platyphylla Del (Moraceae) in mice
شیهو آیشاتو نبارا اومی ماگاجی محمد گاربا یو جمیلو احمد ابوبکرBackground &Aim: Depression is a heterogeneous mood disorder affecting both people in developing and developed countries. The drugs used in its management are associated with adverse effects and delayed response which compromise their therapeutic benefits. This make MoreBackground &Aim: Depression is a heterogeneous mood disorder affecting both people in developing and developed countries. The drugs used in its management are associated with adverse effects and delayed response which compromise their therapeutic benefits. This makes it worthwhile to look for antidepressants plants with proven advantage and favourable benefit-to-risk ratio. Ficusplatyphylla is used traditionally in West Africa for the management of mental illnesses.The aim of this study was to evaluate the antidepressant potential of the methanol stem bark extract of F.platyphylla. Experimental: Thin layer chromatographic finger prints of the extract was established. The oral median lethal dose of the extract was estimated using OECD 420 guidelines. Antidepressant activity of the extract at doses of 125-500 mg/kg was evaluated using tail suspension test (TST) and forced swim test (FST). The Effects of the extract on motor co-ordination deficit and locomotion were evaluated using beam walking assay (BWA) and open field test (OFT) respectively. Results and Discussion: The chromatographic profile suggested the presence of steroids, tannins, flavonoids, alkaloids and saponins. The LD50 was found to be ≥2000 mg/kg orally. The extract significantly (p<0.01) and dose dependently (125, 250 and 500 mg/kg) decrease the duration immobility in the TST and FST. There is no significant increase in the number of lines crossed and on the number of foot slips in the OFT and BWA respectively. Industrial and Practical recommendations: The methanol stem bark extract of F.platyphylla possesses antidepressant activity. The phytoconstituents found present in the plant assumed to be responsible for the activity can be characterized and isolated to serve as lead compounds in the treatment of depression. Manuscript profile -
Open Access Article
5 - Comparison of Two Spectrophotometric Methods for Quantifying Total Hydroxycinnamic Acids in Coneflower (Echinacea purpurea) Preparations
حسین مهدوی محمد رضا نادری محمدحسین اسماعیلیBackground & Aim: Hydroxycinnamic acids are one of the most important bioactive substances of Echinacea drugs. These compounds possess immuno-enhancing activity and thus, total hydroxycinnamic acids are mostly used as the main criterion for quality control of Echina MoreBackground & Aim: Hydroxycinnamic acids are one of the most important bioactive substances of Echinacea drugs. These compounds possess immuno-enhancing activity and thus, total hydroxycinnamic acids are mostly used as the main criterion for quality control of Echinacea purpurea and its drugs. Hence, the quality control of Echinacea requires to developing the reliable methods which are simple and also have a suitable accuracy in measuring total hydroxycinnamic acids.The current study was performed in order to sets a simple method for quantifying total hydroxycinnamic acids of Echinacea and then, comparison of this method which named as the AlCl3 method with the method of European pharmacopoeia (EP). Experimental: Total hydroxycinnamic acids of 10 coneflower samples were determined using AlCl3 and EP methods and the amounts obtained by these two methods, were compared using statistical criterion. Results: Accuracy of AlCl3 method in measuring total hydroxycinnamic acids of Echinacea was not suitable, as the relative difference between amounts measured by this method and those measured by EP method was 50-130%. Comparison of this method with EP method indicated that performance of AlCl3 method for quantifying total hydroxycinnamic acids of Echinacea drugs was very poor and low value of willmott index of agreement (d= 0.53) and high value of relative error (RE= 0.83) were obtained. Recommended applications/industries: Due to non-selective reaction of Al(III) with hydroxycinnamic acids, the AlCl3 method is not suitable for measuring the total hydroxycinnamic acids of Echinacea and its preparations. Manuscript profile -
Open Access Article
6 - Antibacterial, Antifungal Properties and Chemical Composition of Essential Oils of Satureja hortensis L. and Satureja khuzestanica Jamzad
احمدرضا گلپرور محمد مهدی قیصری امین هادی پناه مجتبی خرمیBackground & Aim: The aim of this study was to investigate the antibacterial, antifungal properties and chemical composition screening of essential oils of Satureja khuzestanica Jamzad and Satureja hortensis L. Experimental: For determination of antibacterial and an MoreBackground & Aim: The aim of this study was to investigate the antibacterial, antifungal properties and chemical composition screening of essential oils of Satureja khuzestanica Jamzad and Satureja hortensis L. Experimental: For determination of antibacterial and antifungal activity of these essential oils, Staphylococcus aureus and Candida albicans were targeted, respectively. The minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of each essential oil were determined individually. Also, chemical composition of essential oils was identified and characterized by gas chromatography armed by mass spectrometry (GC–MS). Results: The total of 22 and 21 compounds were identified in the essential oils of aerial parts of S. hortensis and S. khuzestanica, respectively. The major components of S. hortensis essence were carvacrol (56.36%), γ-terpinene (24.75%), p-cymene (5.81%) and the major constituents of S. khuzestanica essence was reported carvacrol (69.62%), γ-terpinene (9.25%) and p-cymene (8.36%). The obtained results showed the antibacterial and antifungal activity of both extracted essential oils against the tested pathogens. The MIC and MBC of S. hortensis and S. khuzistanica essential oils against S. aureus were determined 0.1 and 0.5 μl/ml, and 0.1 and 0.2 μl/ml against C. albicans, respectively. Recommended applications/industries: The results showed that S.hortensis oil had higher antimicrobial activity compare to S. khuzistanica. Manuscript profile -
Open Access Article
7 - Antimicrobial Effects of Zataria multiflora Essential Oils on Acinetobacter Strains Isolated from Clinical Specimens
خدیجه رضایی کیخواهی غلامرضا باقری مهدی حسن شاهیان سعیده سعیدیBackground & Aim: The aim of this study was to investigate the antimicrobial effects of Zataria multiflora against some Acinetobacter baumannii strains isolated from clinical samples. Experimental: Twelve strains of Acinetobacter baumannii were isolated from referr MoreBackground & Aim: The aim of this study was to investigate the antimicrobial effects of Zataria multiflora against some Acinetobacter baumannii strains isolated from clinical samples. Experimental: Twelve strains of Acinetobacter baumannii were isolated from referred patients in Zabol hospital. Essential oil of Zataria multifloraspecies was extracted using Clevenger device. Minimum Inhibitory Concentration (MIC) and Minimum Bacterial Concentration (MBC) of essential oil on mentioned bacteria were determined using micro dilution broth method at six different concentrations. Results: The results of this study showed that the lowest inhibitory concentration of essential oil against bacteria was 0.31 mg/ml, and only one strain of bacteria was inhibited. However, the highest inhibitory concentration was estimated 10 mg/ml. Recommended applications/industries: The results showed that the antimicrobial effects increased with increasing in essential oil concentration and the essence showed good antimicrobial activity even at low concentrations. With the use of essential oil of Zataria multiflora against bacterial pathogens, a good antimicrobial agent can be obtained without any side effects. Manuscript profile -
Open Access Article
8 - Antimicrobial Effect of Polylophium involucratum Essential Oil on Oral Bacteria
سامان ایوبی زینب حاجیان حبیب حبیب پور سیده صفا کاظمی جعفر آقاجانی پونه یزدانیBackground & Aim: Due to the prevalence of oral bacteria, their complications and increased microbial resistance and also recognition of the antibacterial properties of Polylophium involucratum, in this study, the antimicrobial properties of this plant essential oil MoreBackground & Aim: Due to the prevalence of oral bacteria, their complications and increased microbial resistance and also recognition of the antibacterial properties of Polylophium involucratum, in this study, the antimicrobial properties of this plant essential oil were tested in different dilutions on oral bacteria at the Faculty of Microbiology of the Islamic Azad University of Lahijan in 2015. Experimental: In this study, the antibacterial properties of Polylophium involucratum essential oil at different concentrations of1: 6, 1: 12, 1: 24, 1: 48 and 1: 96, were tested on oral bacteria including Streptococcus mutans and Streptococcus sanguinis with disk fusion method. Results: According to results, the Polylophium involucratum essential oil had a greater antibacterial effect on the Streptococcus sanguinis than the Streptococcus mutans. The highest inhibition zone values were observed against the Streptococcus sanguinis, ranging from 18mm to 27mm. Also, the antibacterial properties of polylophium involucratum essential oil were higher than other chemical drugs.Recommended applications/ industries: The results of this study indicated the antibacterial effect of the Polylophium involucratum essential oil on some pathogenic bacteria, especially Streptococcus mutans and Streptococcus Sanguis, which can be used as a herbal antibiotic with fewer complications than usual antibiotics for treatment of disease. Manuscript profile
-
The rights to this website are owned by the Raimag Press Management System.
Copyright © 2021-2024