Journal of Medicinal Herbs, "J. Med Herb"(Formerly known as Journal of Herbal Drugs or J. Herb Drug): 1 (4)

Open Access Article

1 - Effect of oven and shade drying methods on essential oil yield and chemical composition of Kelussia odoratissima Mozaff.
فرنام میرحسینی مهدی رحیم ملک عبدالله قاسمی پیربلوطی

Background & Aim: Kelussiaodoratissima Mozaff is a valuable plant of Apiaceae family that is used as medicinal and aromatic herb. According to the importance of drying treatment on quality and quantity of essential oil, the effect of different drying methods on esse More

Background & Aim: Kelussiaodoratissima Mozaff is a valuable plant of Apiaceae family that is used as medicinal and aromatic herb. According to the importance of drying treatment on quality and quantity of essential oil, the effect of different drying methods on essential oil yield and chemical composition of Kelussia odoratissima Mozaff was examined in this research. Experimental: This research done in completely randomized design with three replications at Research Center for Medicinal Plants, I.A.U., Shahrekord Branch, Iran. Drying methods, included air drying at shade and ambient temperature, oven 45 °C and fresh sample. The hydro-distillation essential oil was analyzed using GC and GC/MS. Results & Discussion: The results indicated that there was significant difference among drying methods on the essential oil yield and chemical composition. The main component was (Z)-ligustilide that significantly increased in oven-drying (68.3%), while this compound significantly decreased in fresh sample (16.6%). The main compound in fresh sample was thymol with 12.3% that had significant difference with drying treatments. Recommended applications/industries: The results indicated the positive effect drying methodology on essential oil content and oil compositions of Kelussiaodoratissima. Manuscript profile

Open Access Article

2 - Effect of the extract from some medicinal plants against Hyalomma marginatum
امیرحسین مهدویان سید رضا حسینی عبدالله قاسمی پیربلوطی رحمان عبدی زاده

Hyalomma marginatumis a hard-bodiedtickfound on animals. This tick has been implicated in the transmission ofBahig virus, apathogenicarboviruspreviously thought to be transmitted only by mosquitoes.

Hyalomma marginatumis a hard-bodiedtickfound on animals. This tick has been implicated in the transmission ofBahig virus, apathogenicarboviruspreviously thought to be transmitted only by mosquitoes. Manuscript profile

Open Access Article

3 - Effect of garlic (Allium sativum L.) extract on some heamatological parameters and immune response of rainbow trout fingerlings
سید پرویز دادوران منصوره قائنی ابوالفضل عسکری ساری

Background & Aim: Continuous use of antibiotics leads to drug resistance and thereby to a reduced efficacy of the drugs. Antibiotics accumulate in the environment and fish pose a potential risk to consumers and to the environment.Increased public awareness of the ne More

Background & Aim: Continuous use of antibiotics leads to drug resistance and thereby to a reduced efficacy of the drugs. Antibiotics accumulate in the environment and fish pose a potential risk to consumers and to the environment.Increased public awareness of the negative effects caused by overexposure to synthetic chemicals has led to the search for ‘‘green drugs’’, such as organic and synthetic chemical-free food products. The main goal this work was effect of Allium sativum on some parameters and immune response of rainbow trout fingerlings. Experimental: A 500 fish with weight 10.47±0.29 g were purchased from a fish farm of Yasoj, Southern Iran. In this study, 15 fiberglass tanks (300 L) were used. Experimental treatments were different levels of A. satinum extract included 0.05, 0.1, 0.15, and 0.2 g/kg that were added to the diet. Control group was no add supplement to the diet. In final, biochemicals and hematologals were analyzed. Results & Discussion: Results indicated that 0.05 g/kg garlic extract no had on some paramteres, including RBC, hematocrite percent, hemoglobin and white blood cell, while other experimental groups had significant effects on the paramters serum. The most of albomin and globulin were obtined from 0.05 g/kg garlic extract trteatment. The highest of lysozyme activity was observed in 0.1 g/kg garlic extract and the lowest lysozyme activity was obtined from control group. Recommended applications/industries: The obtained results indicated that A. sativum extract had immunostimulatory effect on these immunological variables of fingelings of rainbow trout and the best levels of extract effect 0.15 g/kg is recommended. Manuscript profile

Open Access Article

4 - Effects of aluminosilicate zeolite application on morphological traits and chemical compositions of Aloe (Aloe vera L.) under drought stress
سارا یاری پژمان مرادی فرحناز خلیقی سیگارودی

Background & Aim: Aloe vera is used in the food and pharmaceutical as an aid to effective treatment. The purpose of this study is to improve growth, increase production of valuable metabolites and increase the sugars in Aloe vera gel with low cost and high efficienc More

Background & Aim: Aloe vera is used in the food and pharmaceutical as an aid to effective treatment. The purpose of this study is to improve growth, increase production of valuable metabolites and increase the sugars in Aloe vera gel with low cost and high efficiency under water stress conditions. Experimental: In this study, Aloe vera potted in greenhouse conditions with four levels of zeolite including 0, 11, 22, and 44 g in 5 kg pots of soil in three replications. The pots were treated under three irrigation levels for five months. Experimental treatments included irrigation in once a week, once every two weeks, and once every three weeks. Some characteristics, as well as amount of production barbaloin and sugars in the plant were measured by HPLC. The data were analyzed using the MSTATC statistical software. Results & Discussion: The study of simple effects and interactions of zeolite application and levels of irrigation, The best results traits were obtained from 22 g Zeolite treatment in 5 kg pots of soil and once every three weeks irrigation. The highest amount of barbaloin was observed in 44 g Zeolite treatment in 5 kg pots of soil with once a week irrigation. The highest amount different sugars was obtained from 44 g Zeolite treatment in 5 kg pots of soil with once every two weeks irrigation. Recommended applications/industries: Zeolite is effective in improving the morphological traits, which in this study increased amount of barbaloin, and levels of polysaccharides in Aloe vera gel under water stress conditions. Manuscript profile

Open Access Article

5 - Identification of chemical composition of essential oil from the leaves of Achillea millefolium subsp. elbursensis
منصوره قوام

Background & Aim: Achillea millefolium is one of the most valuable medicinal and industrial species, which is available in the Iran pastures, and it belongs to the Asteraceae family. This plant wild grows in plains, roadsides and mountain areas. Therapeutically, it More

Background & Aim: Achillea millefolium is one of the most valuable medicinal and industrial species, which is available in the Iran pastures, and it belongs to the Asteraceae family. This plant wild grows in plains, roadsides and mountain areas. Therapeutically, it has been a healer of wounds, and due to having tannins and bitter and aromatic substances, it has an effect on the nervous system and heart. The plant has two subspecies in Iran, including Achillea millefolium subsp. elbursensis and Achillea millefolium subsp. millefolium. These two subspecies, in terms of the apparent specificities, have been very similar, and only in terms of the height, size and color of the inflorescence, are different from each other. The main aim of this study was to identify chemical composition of essential oil from the leaves of Achillea millefolium subsp. elbursensis. Experimental: The samples of leaves of Achillea millefolium subsp. elbursensis, during flowering, were collected from a natural habitat in Dizin (3350 m a.s.l). The essential oil of the plant was isolated by hydro-distillation. Chemical composition of volatile oil of A. millefolium subsp. elbursensis was analyzed by capillary GC and GC/ MS. Results & Discussion: Results indicated that essential oil yield of A. millefolium subsp. elbursensis was 0.82% (v/w). According to results of GC/MS analysis for the essential oil, 20 compounds identified. The main constituents in the essential oil of A. millefolium subsp. elbursensis was chamazulene (69.2%), 1,8-cineole (4.9%), and E-caryophyllene (4.4%). Recommended applications/industries: Based on the results of this study, the subspecies elbursensis, is a rich and unique source for chamazulene, which should be preserved as an indigenous genetic resource, in the natural environment, and strategies for its culture and building mass, must be provided. Manuscript profile

Open Access Article

6 - Total phenolic contents in sponge cake with different concentrations of the leaves of lemon balm
ندا سادات نوری زاده محمد حجت الاسلامی جواد کرامت

Background & Aim: Nowdays consumers prefer to eat healthier foods, therefore producers and researchers are involved to improve the variety, quality, taste of food products. Lemon balm is a perennial, aromatic, herb that contains many phenolic compounds. In this rese More

Background & Aim: Nowdays consumers prefer to eat healthier foods, therefore producers and researchers are involved to improve the variety, quality, taste of food products. Lemon balm is a perennial, aromatic, herb that contains many phenolic compounds. In this research the effect of additing lemon balm powder (by reducing of wheat flour in formulation, instead) on qualities of sponge cakes were investigated.Experimental: Samples were prepared by different addiing lemon balm powder (2.5, 5, 7.5, 10 percent), the control sample was also prepared according to standard sponge cake formulation.then, phenolic compounds amount were analyzed by HPLC.Results & Discussion: The samples contained up to 7.5 percent lemon balm powder had a good acceptance and it could be considered as a food containing more phenolic compound. Manuscript profile

Open Access Article

7 - Phytochemistry of essential oil from different parts of Artemisia aucheri Boiss collected from Chaharmahal va Bakhtiari province, Iran
سپیده میرزائیان مهدی اورعی عبدالله قاسمی پیربلوطی

Manuscript profile

Open Access Article

8 - Effect of ellagic acid on thiol levels in different brain tissue in an animal model of Parkinson's disease
مریم رفیعی راد زینب عیدی پور

Background & Aim: Parkinson's disease (PD) can be created with loss of dopaminergic substantial nigra neurons which is widely associated with oxidative stress and reduced glutathione (GSH), as the most important and abundant thiol in tissues and one of the antioxida More

Background & Aim: Parkinson's disease (PD) can be created with loss of dopaminergic substantial nigra neurons which is widely associated with oxidative stress and reduced glutathione (GSH), as the most important and abundant thiol in tissues and one of the antioxidant defense, is one of the earliest biochemical events related to Parkinson's and consumption of antioxidants has a protective effect. In the present study, effect of ellagic acid on the rate of thiol groups has been studied within the hippocampus, striatum, cortex and cerebellum tissues in Parkinson's disease. Experimental: In this study were used 40 adult male rats that were divided randomly into eight groups: control, Parkinson's, and three Parkinson groups that once daily for 14 days received the gavage from doses 10, 25, and 50 mg/kg of ellagic acid. Parkinson's disease was induced with injection of 8 µg of 6_ hydroxy dopamine (6-OHDA) nerve toxin in 2 ml of saline containing 1% ascorbic acid in the middle-anterior bundle (MFB) of the left cerebral hemisphere of rats. After 14 days all rat brain were collected for the isolation and measurement of tissue thiol. Results & Discussion: In the PD group, in the all tissues observed a significant decrease in the thiol levels than the control group and administered ellagic acid in particular, 25 and 50 mg/kg was able to induce the effect of increase in the all tissues. This increase was significant in all tissues except cerebellum than PD group. Recommended applications/industries: Ellagic acid with having the ability to increase thiol can be used for treating and preventing progression of Parkinson's disease that created by oxidative stress. Manuscript profile

Open Access Article

9 - Evaluation of the effect of Eucalyptus and Thyme essential oils and aqueous extract of Artemisia annum and synergistic combination of pyrimethamine-sulfadiazine on acute toxoplasmosis in Balb / c mice
سید رضا حسینی آرین اسعدپور بهزادی

Introduction & Objective: Toxoplasmosis is an infection caused by Toxoplasma gondii parasite and is one of the most common parasitic infections in humans and other warm-blooded animals. In this study, the effect of Eucalyptus and Thyme essential oils and aqueous ext More

Introduction & Objective: Toxoplasmosis is an infection caused by Toxoplasma gondii parasite and is one of the most common parasitic infections in humans and other warm-blooded animals. In this study, the effect of Eucalyptus and Thyme essential oils and aqueous extract of Artemisia as well as the synergistic combination of pyrimethamine-sulfadiazine on acute toxoplasmosis in a mouse model was investigated.Materials and Methods: In order to investigate the effect of Eucalyptus and Thyme essential oils and Artemisia aqueous extract as well as the synergistic composition of pyrimethamine-sulfadiazine on acute toxoplasmosis in a mouse model, 44 Balb / c mice with Tuxvit tux Peritoneal infection was divided into 11 groups of 4. To 9 groups of concentrations of 150 mg / kg / day, 300 mg / kg / day and 600 mg / kg / day of eucalyptus and thyme essential oils and aqueous extract of Artemisia 24 hours after infection for 7 days orally Was fed. One group was treated orally with the chemical combination of pyrimethamine (dose 10 mg / kg / day) and sulfadiazine (dose 50 mg / kg / day) for 10 hours after infection for 10 days and another group as The patient's control was considered.Results and Discussion: The results showed that there was no obvious difference in terms of survival time between the groups treated with essential oil and plant extracts and the patient control group and all died by the sixth day, while consuming mice. The chemicals all survived, and after the peritoneal fluid and brain of one of the mice in this group were inoculated separately into two groups of healthy mice intraperitoneally, it was observed that the mice given the peritoneal fluid Inoculated, all survived, while mice inoculated with brain all perished. This result indicated that the combination of pyrimethamine-sulfadiazine in this dose is quite effective on acute toxoplasmosis, but is not able to eradicate and eliminate parasitic cysts in the brain.Practical / Industrial Recommendation: It is better to do more comprehensive research on the effects of different species of these plants on Toxoplasmosis in vitro and in vivo so that an effective and safe drug against Toxoplasmosis can be presented in the world. Manuscript profile

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