The comparison of anti-diarrhea effects of two herbal compounds namely Elaeagnus Angustifolia (Oleaster) and Plantago major powders in Dogs

Subject Areas : Journal of Medicinal Herbs, "J. Med Herb" (Formerly known as Journal of Herbal Drugs or J. Herb Drug)

علیرضا  لطفی ¹ (Faculty of Veterinary Medicine, Shahrekord Branch, Islamic Azad University, Shahrekord, Iran)
سام  ترکان ² (Department of Small Animal Internal Medicine, Faculty of Veterinary Medicine, Shahrekord Branch, Islamic Azad University, Shahrekord, Iran)
محسن  جعفریان دهکردی ³ (Department of Pathology, Faculty of Veterinary Medicine, Shahrekord Branch, Islamic Azad University, Shahrekord, Iran)

Received: 2016-02-19 Accepted : 2016-04-02 Published : 2016-07-01

Keywords: PET, Herbal drugs, Nutritional diarrhea, Oleaster powder, Plantagel,

Abstract :

Background & Aim:Increasing the tendency in families for taking care of pets makes people pay more attention to their disease especially the common ones. In recent years the tendency to use of herbal drugs has increased in animals. Herbal drugs are plants that one or some of their members have effective. We supposed that the Elaeagnus angustifolia(oleaster) powder has the plantagel. Therefore, the aim of this study is to compare the oleaster powder herbal compounds and plantagel as anti-diarrhea in dogs. Experimental: This study was done on 12 male dogs collar (3 quadri groups) with the similar approximate weight and similar age in veterinary clinic of Islamic azad university of Shahrekord branch. Sana flower herbal syrup was used to cause the diarrhea in all 3 groups. They received 15 mg/kg every 12 hours and all groups were suffering from diarrhea. Three groups were studied including testifier group without remedy, the first care group that received 5 mg/kg of oleaster and the second care group that received the plantagel powder every day and during this period of time the whole index related to diarrhea were exanimate whether on aspect of clinical or mortal factors. Results: By looking at the mortal indices, it was observed that the percentage of hematocrit in plantagel and oleaster groups in comparison with testifier group in recovery time was significantly different (P>0.05), that shows the recovery of mortal hematocrit index. Also the percentage of neutrophils in oleastergroup with testifier and plantagel groups was observed a meaningful difference which is reducethat is a sample of meaningful increase in comparison with other groups (P>0.05). Also by sampling from excrement, the numbers of the bacteria showed a meaningful difference in oleaster and plantagel group in comparison with testifier group (P>0.05). Recommended applications/ industries: The use of oleaster powder as dose and time dependent causes reducing the duration of diarrhea because of the prehensile materials in oleaster.

References:

Asadiar, L.S, Rahmani, F. and Siami, A. 2012. Assessment of genetic variation in Russian olive (Elaeagnus angustifolia) based on morphological traits and random amplified polymorphic DNA (RAPD) genetic markers. Journal of Medicinal Plants Research, 6(9), 1652-1661.

Awe E.O., Kolawole, S.O. Wakeel, K.O. and Abiodun O.O. 2011. Antidiarrheal activity of Pyrenacanthastaudtii Engl. (Iccacinaceae) aqueous leaf extract in rodents. Journal of Ethnopharmacology, 137, 148-153.

Beara, I.N., Lesjak, M. M. Orcic D., Z. Simin, N. D., Cetojevic-Simin,D.D., Bozin, B. N., Mimica-Dukic, N.M. 2012. Comparative analysis of phenolic profile, antioxidant, anti-inflammatory and cytotoxic activity of two closely-related Plantain species: Plantagoaltissima L. and Plantagolanceolata L., LWT-Food Science and Technology. 47, 1, 64-70.

Brooks, G.F., Karen, C. and Caroll, M.D. 2010. Jawetz, Melnick, &Adelberg’s Medical Microbiology. New York, NY: McGraw-Hill, pp. 145-371.

Burkhill, I.H. 1966. A dictionary of the economic products of the Malay Peninsula. Kuala Lumpur: ministry of agriculture and co-operatives, Malaysia. Vol. 2.

Choi J.S., Kim, J.W., Cho, H.R., Kim, K.Y., Lee, J.K., Sohn, J.A. and Ku, S.K. 2014. Laxative effects of fermented rice extract in rats with loperamide-induced constipation. Experimental and Therapeutic Medicine, 8, 1847-1854.

Chopra, R.N, Nayar, S.L. and Chopra, I.C. 1986. Glossary of Indian Medicinal Plants (Including the Supplement). New Delhi, India: Council of Scientific and Industrial Research, pp. 130-133.

Eliassi, A. et al. 2008. Intragastric effect of ElaeagnusangustifoliaL. fruit on gastric acid secretion in a rat pylorusligated model. Journal of Medicinal Plants, 7, 82-91.

Eliassi, A. et al. 2009. Effect of oral (systemic) ElaeagnusangustifoliaL. fruit on stimulated gastric acid secretion in unconscious rat and on basal acid secretion in conscious rat. Journal of Medicinal Plants, 8, 123-130.

Gálvez, M., Martín-Cordero, C., Houghton, P.J., Ayuso, M.J. 2005. Antioxidant activity of methanol extracts obtained from Plantago species. Journal of Agricultural and Food Chemistry, 53(6), 1927-33.

Gorkiewicz G., Thallinger, G.G., Trajanoski, S., Lackner, S., Stocker, G., Hinterleitner, T., Gully and Hogenauer, C. C. (2013). Alterations in the colonic microbiota in response to osmotic diarrhea. PLoS One, 8, p. e55817.

Karimi, G., Hosseinzadeh, H., Rassoulzadeh, M., Razavi, B.M. and Taghiabadi, E. 2010. Antinociceptive effect of Elaeagnus angustifolia fruits on sciatic nerve ligated mice. Iranian Journal of Basic Medical Sciences, 13(3), 97-101.

Katerere, D.R. and Luseba, D. 2010. Ethnoveterinary Botanical Medicine Herbal Medicines for Animal Health. CRC Press; Boca Raton, FL, USA:pp. 1-434.

Mabey, R. 1988. The complete new herbal- A practical guide to herbal gardening. Elm Tree Books. London:

McGaw, L.J. and Eloff, J.N. 2010. Methods for evaluating efficacy of ethnoveterinary medicinal plants. In: Katerere D.R., Luseba D., editors. Ethnoveterinary Botanical Medicine: Herbal Medicines for Animal Health. CRC Press; London, UK: pp. 1-24.

Mpoke, L. and Mathiu, M. 2005. Indigenous knowledge (IK) and practices in traditional animal healthcare in the arid and semi-arid lands (ASALs): The challenges and future on animal health and production services delivery. Kenya Veterinary, 29, 99-103.

Muhamed, Z. and Mustafa, A.M. 1994. Traditional Malay Medicinal Plants. Kuala Lumpur: PenerbitFajarBaktiSdn. Bhd.

Perry, L.M. (1980). Medicinal plants of the east and southeast Asia. London: MIT Press, 131.

Pommerville, J.C. 2011. Alcamo’s Fundamentals of Microbiology. Sudbury, Canada: Jones & Bartlett Publishers, pp. 850-875.

Rahman, K., Barua Islam, S. F., Islam, R., Sayeed Parvin, M.A. and Islam, S. E. 2013. Studies on the anti-diarrheal properties of leaf extract of Desmodiumpuchellum. Asian Pacific Journal of Tropical Biomedicine, 3, 639-643.

Samuelson, A.B. 2000. The traditional uses, chemical constituents and biological activities of Plantagomajor. Journal of Ethnopharmacology, 71(1-2), 1-21.

Sharifa, A. A., Neoh, Y. L., Iswadi, M. I. et al. 2008. Effects of methanol, ethanol and aqueous extract of Plantago major on gram positive bacteria, gram negative bacteria and yeast. Annals of Microscopy, 8, 42-44.

WHO. 2003. Traditional Medicine; Fact Sheet. WHO; Geneva, Switzerland: Number 134.

Xu Q., Shen, Z., Wang,Y., Guo, S. F., Li, Y. and Wang, C. 2013. Zhou Anti-diarrhoeal and anti-microbial activity of Flospopuli (male inflorescence of PopulustomentosaCarrière) aqueous extracts Journal of Ethnopharmacology, 148, 640-64.