List of Articles

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  1 - Chemical composition of the essential oil from the leaves of Marrubium vulgare L.from Iran
  احمدرضا گلپرور امین هادی پناه علی مهراز مهرابی آرزو آرمین
  Background & Aim: White horehound (Marrubium vulgare L.) is a perennial medicinal plant of the family Lamiaceae. The aim of this study was to identify of the chemical components of white horehound collected from Isfahan. Experimental: The aerial parts of M. vulgare More

  Background & Aim: White horehound (Marrubium vulgare L.) is a perennial medicinal plant of the family Lamiaceae. The aim of this study was to identify of the chemical components of white horehound collected from Isfahan. Experimental: The aerial parts of M. vulgare were collected from (Kamu Mountain) Isfahan province central of Iran, during 2014. The essential oils of samples were obtained by hydro-distillation, and analyzed using gas chromatography–mass spectrometry (GC–MS). Results & Discussion: Results of GC/MS indicated that 44 compounds were identified in the essential oil from the aerial parts of M. vulgare. The major constituents of the essential oil were β-caryophyllene (32.19%), (E)-β-farnesene(11.39%), 1,8-cineole (8.17%) and α-pinene (6.64%).A comparison of our results with different reports, differences in the volatile composition of the plants could be attributed to genetic (genus, species, and ecotype), chemotype, distinct environmental and climatic conditions, seasonal sampling periods, geographic origins, plant populations, vegetative plant phases, and extraction and quantification methods. Industrial and practical recommendations: The biosynthesis of secondary metabolites, although controlled genetically, is strongly affected by the environmental influences of a particular growing region. Manuscript profile
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  2 - Effects of safflower oil on FBS and lipid profile in alloxan induced diabetic rats and its mechanism
  پریوش رحیمی محبوبه سترکی منیر ویودی
  Background & Aim: Diabetes mellitus often has been referred to as a syndrome of disordered metabolism, usually due to a combination of hereditary and environmental causes, resulting in abnormal of high blood sugar levels (hyperglycemia). Nowadays, no-drug treatments More

  Background & Aim: Diabetes mellitus often has been referred to as a syndrome of disordered metabolism, usually due to a combination of hereditary and environmental causes, resulting in abnormal of high blood sugar levels (hyperglycemia). Nowadays, no-drug treatments (medicinal plants) are novel therapeutic approaches in the treatment of diabetes. Experimental: This study aimed at assessing the effect of Carthamustinctorius L oil on the blood glucose and lipid profile in diabetic rats. Eighteen male rats were divided into 3 groups as follows: control, diabetes treated with glibenclamide and diabetes treated with 200 mg/kg b.wt safflower oil. Diabetes was induced in rats by intraperitoneal administration of single dose of alloxan monohydrate (120 mg/kg body weight). The oil of (Carthamustinctorius L.) at a dose of 200 mg/kg b.wt was administered every other day to the diabetic rats for a period of 30 days. Results: The results show that the safflower oil exhibited significant hypoglycemic and hypolipidemic effect in hyperglycemic rats. In fact, phenolic compounds and free fatty acids in safflower oil play an important role in regulating animal insulin secretion response and glucose homeostasis. Manuscript profile
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  3 - Effects of Jasmonic acid on essential oil yield and chemical compositions of two Iranian landraces of basil (Ocimum basilicum) under reduced irrigation
  فاطمه ملک پور اعظم سلیمی عبدالله قاسمی پیربلوطی
  Background & Aim: Sweet basil (Ocimum basilicum), a plant that is extensively cultivated in some countries, is used to enhance the flavour of salads, sauces, pasta, confectioneries and other products as both a fresh and dried herb. The effect of foliar application o More

  Background & Aim: Sweet basil (Ocimum basilicum), a plant that is extensively cultivated in some countries, is used to enhance the flavour of salads, sauces, pasta, confectioneries and other products as both a fresh and dried herb. The effect of foliar application of Jasmonic acid and reduced irrigation on essential oil yield and chemical components of two Iranian landrace of basil (Ocimum basilicum) were investigated. Experimental: Treatments comprised control, 0.0, 200 and 400 µL Jasmonic acid applied to plants under normal irrigation and stressed conditions (30 and 60% F.C) based on a completely randomized design with three replications. The essential oils from the aerial parts of basil were analyzed by GC-FID and GC/MS. Results & Discussion: Results indicated that the different levels of Jasmonic acid and irrigation had significant effects on oil yield and some main components of the essential oil. The highest value of oil content was obtained from application of 400 µL JA. Percentage of some chemical constituents in the essential oil extracted from the plants under stress was higher than non-stressed plants. Foliar application of Jasmonic acid significantly improved methyl chavicol in the oils, but reduced Germacrene- D, α-Cadinol and δ-Cadinene amounts. Industrial and practical recommendations: Since, essential oil of basil, particularly methyl chavicol component, have many application in pharmaceutical and perfumery industry and has health benefits such as antiviral, antibacterial and antispasmodic activity, we can use Jasmonic acid elicitor to enhance the therapeutic properties of basil and also essential oil content and methyl chavicol of plant. Manuscript profile
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  4 - Chemical Composition of the Volatile oils of three Lamiaceae species growing wild in North of Iran
  سالار حافظ قران بشرا آزادی هدایت حسین
  Background & Aim: The Lamiaceae or Labiatae (commonly referred to as the mint or deadnettle family) are an exceedingly large and widespread of flowering plants (Angiospermae). Most member of Lamiaceae plants are used in Iranian folk medicine as stimulant, antiseptic More

  Background & Aim: The Lamiaceae or Labiatae (commonly referred to as the mint or deadnettle family) are an exceedingly large and widespread of flowering plants (Angiospermae). Most member of Lamiaceae plants are used in Iranian folk medicine as stimulant, antiseptic, aphrodisiac, stomachic, expectorant, carminative, anti-diarrheic and anti-bacterial. The aim of the present work was to obtain a better insight into the nature of essential oil. Experimental: The essences of three Lamiaceae species viz., Satureja macrantha C.A. Mey., Ziziphora persica Bunge, and Lavandula stoechas L. obtained by hydrodistillation method of flowers growing wild in the north of Iran. The study led to the identification of 67 components by a combination HP-5 GC-FID and GC-MS analytical techniques and the oil yields were 1.3 %, 1.64 %, and 1.16 % on fresh flowers, respectively. Results & Discussion: The chemical components of S. macrantha were found to contain mainly: Carvacrol (43.3 %), g-Terpinene (24.1 %) and p-Cymene (21.6 %). On the other hand the major oil components for Z. persica were Isopulegone (46.6 %), followed by p-mentha-1(7),8-diene (16.4 %), 1,8-Cineole (7.0 %), Isomenthol (5.5 %) and Isoledene (3.3 %), accounting for 98.0 % of the total components. Camphor (61.5 %), 1,8-Cineole (10.1 %), Fenchone (4.2 %) and Linalool (3.8 %) were found to be the major constituents of the oil of L. stoechas. The essential oils of S. macrantha, Z. persica, and L. stoechaswere identified by much larger amount of monoterpenes (96.52 %, 89.31 %, and 93.49 %, respectively) and sesquiterpenes (1.87 %, 8.10 %, and 5.04 %, respectively). Industrial and practical recommendations: Based on the results of this study, the chemical variations of threevolatile oils might be correlated with geographical regions and environmental conditions (temperature, humidity, interaction with other species and etc.) play a significant role in biosynthesis of the components of the oil Manuscript profile
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  5 - Folk Herbal Veterinary Medicines of Tehran Watershed (Iran)
  اردوان قربانی فرزاد میرزائی آقجه قشلاق سمیرا کرامتی جبه‌دار
  Background & Aim: The use of medicinal plants is an option for livestock farmers who do not want to use allopathic drugs under certified organic programs or cannot afford to use allopathic drugs for minor health problems of livestock. Thus, the main aim of this stud More

  Background & Aim: The use of medicinal plants is an option for livestock farmers who do not want to use allopathic drugs under certified organic programs or cannot afford to use allopathic drugs for minor health problems of livestock. Thus, the main aim of this study is the identification of some ethnoveterinary medicinal plants of Tehran watershed and their medicinal effects on livestock. Experimental: Initially, plant species were collected from the watershed, and then using reliable literature collected species was identified. After that, medicinal plants from veterinary value perspective by comparison with the published literature were determined. Moreover, identified species with disease therapy value were classified. Results & Discussion: Initially 278 medicinal plant species were identified in this area. From those, 47 species were identified with ethnoveterinary medicinal value, which were belonged to 28 families. Identified species were used for treating different disease and syndromes such as parasites (17%), oestrusovis (7%), gastrointestinal diseases (12%), diarrhea (7%), pain killer (9%), mastitis (7%), skin infection (5%), wounds (17%), lack of some vitamins and nutrients (10%) and some other diseases and syndromes such as theileriosis, immunomodulation and bloat in livestock. Industrial and practical recommendations: This information can be improved our knowledge of native plants that are useful for curing animal disease and attempt to conserve the area and its plant species. Manuscript profile
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  6 - The effects of Thyme extrac (Thymus vulgaris) on systemic antibody responses against Influenza and Newcastle disease vaccine in broiler chickens
  فروغ طلازاده منصور میاحی حسین نجف زاده ورزی حدیث نوروزی زاده
  Background & Aim: The recent study was conducted to investigate the effects of Thyme extract in drinking water on immune response of broiler chickens. Experimental: A total of 245 day-old broiler chicks were purchased and 20 chicks were bled for determination mater More

  Background & Aim: The recent study was conducted to investigate the effects of Thyme extract in drinking water on immune response of broiler chickens. Experimental: A total of 245 day-old broiler chicks were purchased and 20 chicks were bled for determination maternal antibody and remaining chicks divided into 5 equal groups. Chickens of group A, B and C received 0.1%, 0.15% and 0.2% ofThyme extract in drinking water for all of the period of experiment, respectively. Chickens of group D did not receive Thyme extract but vaccinated against Newcastle and Influenza diseases. Chickens of group E were kept as control group and did not receive Thyme extract and Newcastle and Influenza diseases vaccines. Chickens of group A, B, C and D were vaccinated with live Newcastle vaccine (B1 strain) intraocularly and AI-ND killed vaccine (subtype H9N2) subcutaneously of neck back. Blood samples were collected before vaccination as well as on days 14, 28 and 35 after vaccination. Ten chickens of each group were bled randomly and antibody titer against Newcastle and Influenza vaccine virus was determined by HI test. Results & Discussion: The results of present study showed that Thyme extract has no effect on antibody response against Newcastle vaccine virus, but 14 days after vaccination, receiving of 0.2% ofThyme extract, significantly increased the specific antibody response against Influenza vaccine virus compared to all groups. Industrial and practical recommendations: Herbs that are rich in flavonoids such as thyme (Thymus vulgaris) extend the activity of vitamin C, act as antioxidants and may therefore enhance the immune function. Manuscript profile
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  7 - Antiulcerogenic activity of stem extract and fractions of Homalium Letestui
  لوییس آمازو جواد اکوکون لوکی نوییدا
  Background & Aim: Homalium letestui Pellegr (Flacourtiaceae) used traditionally by the Ibibios of Southern Nigeria to treat stomach ulcer, malaria and other inflammatory diseases was evaluated for antiulcer properties. Experimental: The effects of ethanol stem extr More

  Background & Aim: Homalium letestui Pellegr (Flacourtiaceae) used traditionally by the Ibibios of Southern Nigeria to treat stomach ulcer, malaria and other inflammatory diseases was evaluated for antiulcer properties. Experimental: The effects of ethanol stem extract of H. letestui (200 – 600 mg/kg) and fractions (Aqueous and Dichloromethane, 400 mg/kg) on experimentally induced ulcer were studied in rats using ethanol, indomethacin, reserpine and histamine –induced ulcer models. Results & Discussion: The extract (200 – 600 mg/kg) inhibited ethanol, indomethacin, reserpine and histamine –induced ulcer models in a dose dependent fashion. The various degrees of inhibitions were statistically significant (p<0.05, 0.01, 0.001). The effects of the extract/fraction were comparable to that of the standard drugs used in indomethacin and ethanol-induced ulcer models with the dichloromethane fraction having the highest activity. Industrial and practical recommendations: The present study demonstrates that stem extract of Homalium letestui might to be useful for the treatment of ulcer. Manuscript profile
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  8 - Chemical Composition of the Volatile Fraction of Perovskia abrotanoides and Nepeta glomerulosa. Growing Wild in Iran by Different Extraction Methods
  پرویز آبرومند آذز کامبیز لاریجانی نرجس کلانتری
  Background & Aim: Essential oils are isolated from different sections of plants such as flowers, seeds, leaves, stems and roots. Essential oils are applied extensively in producing of perfumes, cosmetics, foods, beverages and confectioneries and as ingredients of di More

  Background & Aim: Essential oils are isolated from different sections of plants such as flowers, seeds, leaves, stems and roots. Essential oils are applied extensively in producing of perfumes, cosmetics, foods, beverages and confectioneries and as ingredients of disinfectants and insecticides. Experimental: Essential oil are obtained by several isolation methods, such as hydrodistillation (HD), steam distillation (SD), solid phase micro extraction (SPME), microwave assisted distillation (MAD) and solvent free microwave extraction (SFME). Hydrodistillation, solvent free microwave extraction (SFME) and solid phase microextraction (SPME) methods has been applied to extraction of essential oil from Perovskia abrotanoides and Nepeta glomerulosa growing in Iran. Results & Discussion: Camphor (15.2, 15.50 and 9.02%), 1,8-cineole (15.03, 14.21 and 9.87%) and §-carene (6.4, 7.19 and 9.78%) were the main compounds in the Perovskia abrotanoides essential oil, respectively. Geraniol(12.74%) and β-caryophyllene (10.05%) identified by hydrodistillation whereas carvacrol (70.52%) and β-caryophyllene (4.13%) identified by solvent free microwave extraction that were the main compounds in the Nepeta glomerulosa essential oil. Industrial and practical recommendations: Hence, it can be High amount of sesquiterpenes and low quantity of hydrocarbon monoterpenes were identified in each essential oil. Manuscript profile