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1 - Effect of pomegranate peel extract on oocyte shedding and intestinal pathology in experimental Coccidiosis of broiler chickens
مهدی زینلی طالخونچه الهام مقتدایی

Background & Aim: Coccidial infections cause significant economic damage to the poultry industry every year in different parts of the world, whether clinical or subclinical coccidiosis. Therefore, the aim of this study was to compare pomegranate peel extract with to More

Background & Aim: Coccidial infections cause significant economic damage to the poultry industry every year in different parts of the world, whether clinical or subclinical coccidiosis. Therefore, the aim of this study was to compare pomegranate peel extract with toltrazoril on the excretion of Eimeria oocytes and intestinal pathology. Experimental: In this study, 180 Ross day-old chicks were used. After inoculation of chicks with Eimeria oocytes at the age of 21 days and giving time to symptoms appear, treatment with the commercial drug tolterazuril (2 days) and pomegranate peel extract (7 days) at concentrations of 100, 200 and 400 ppm was started. and fecal specimens were counted. At the end of treatment period, stool specimens were randomly collected and examined for cecal oocyte excretion in chicks, and cecum specimens were tested for histological damage after treatment. Finally, histopathological slides and the statistical analysis of data were reviewed. Results. The results indicated a significant decrease in fecal oocyte excretion, reduction of coccidiosis-related pathological lesions, and elimination of parasitic life in the cecum, in the groups treated with pomegranate peel extract (400> 200> 100 ppm). In the infected and untreated group, cecal hemorrhage, necrosis and life stages of the parasite were observed. These symptoms were also observed mildly in the group treated with 100 ppm of extract. None of the mentioned symptoms were observed in the group treated with 400 ppm of the pomegranate peel extract. Recommended applications/ industries: According to the results of this study and also considering the side effects of drugs, pomegranate peel extract can be used as an adjuvant therapy to control coccidiosis in poultry. Manuscript profile
Open Access Article
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2 - Histopathological investigation of the effect of Viola odorata and Pistacia atlantica extract on acute tendonitis in rats
امیرحسین چراغیان الهام مقتدایی
10.30495/medherb.2022.697141

Background & Aim: Tendon is the connective tissue between bone and muscle. Because of poor blood flow and the possibility of adhesions during repair, tendon injury management is particularlyimportant.Therefore, finding a quick way to repair tendon tissue is one of t More

Background & Aim: Tendon is the connective tissue between bone and muscle. Because of poor blood flow and the possibility of adhesions during repair, tendon injury management is particularlyimportant.Therefore, finding a quick way to repair tendon tissue is one of the targets that has been pursued over the years.Experimental: In this study, 24 male rats were divided into 4 groups, including first group without any treatment, second group receiving dexamethasone (1mg/kg), third group receiving 250 mg/kg Viola odorata and Pistacia atlantica extract, fourth group receiving 500 mg/kg and Pistacia atlantica and Viola odorata extract. After anesthesia of rat acute tendonitis developed. Al the mentioned groups were injected subcutaneously on bigining day, 7 and 21 days after surgery and histopathological evaluation was performed on day 21.Results: The results showed no statistical significance in the number of fibroblasts between different groups. However, dexamethasone groups and the one receiving 500 mg/kg of extract differed significantly from the control group in terms of inflammation and bleeding. Furthermore, the number of fibrocytes in the groups receiving 500 mg/kg and 250 mg/kg doses of Viola odorata and Pistacia atlantica extracts was significantly different from the control and dexamethasone groups (P <0.05).Recommended applications/industries: According to the results, the amount of collagen and fibrocytes in the group treated with 500 mg/kg had a significant difference, compared to other groups, probably due to the anti-inflammatory, antibacterial and antioxidant properties of Viola odorata and Pistacia atlantica. They can be used in traditional medicine along with other medicines. Manuscript profile

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