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        1 - Effect of some of plant extracts on the growth of two Aspergillus species
        سیما یحیی آبادی الناز زیبانژاد منیر دودی
        Background & Aim: In recent years using from plant product has been considered wildly as main factor for preventing pathogenic diseases cassed by attacking viruses, bacteria, fungi and parasites. There are some funguses which could be the factors for affliction of s More
        Background & Aim: In recent years using from plant product has been considered wildly as main factor for preventing pathogenic diseases cassed by attacking viruses, bacteria, fungi and parasites. There are some funguses which could be the factors for affliction of some diseases in human, plants and animals. Plant extracts are those which could act and be used as preventing from these diseases as product of opposed fungus. The main aim of this article is considering the effects of Anethum graveolens, Thymus vulgaris, Coriandrum sativum and Rosa damascena is on standard strains and separated as Aspergillus flavus and Aspergillus fumigatus. Experimental: The sink was used for preventing the development of plant extract and not growing different density of extract were considered separately. The minimum inhibitory concentration (MIC) was calculated by the serial diluted method. Results & Discussion: The result showed that Aspergillus flavus standard (PTCC 5006), nystatin and extracts of A. graveolens, C. sativum and T. vulgaris in equal amount and finally R. damascena had more effects in opposed fungus. About separated strain of this fungus from the environment, nystatin, T. vulgaris, A. graveolens, C. sativum and finally R. damascena had the most effect against fungus. About standard Aspergillus fumigatus (PTCC 5009), the most effective mixtures against fungus were included extracts of A. graveolens, R. damascena, and C. sativum respectively. About separated strain of this fungus until the most effective mixture of opposed fungus respectively were including nystatin, A. graveolens, T. vulgaris, C. sativum and finally R. damascena. The result of this investigation shows that the existence extracts will be the main cause of reducing the growth of fungi. In this case by increasing the extracts of A. graveolens, T. vulgaris, C. sativum and R. damascena will be increased. Industrial/Practical recommendation: By proving the effect distributing the extracts leaves of Anethum graveolens, Thymus vulgaris, Coriandrum sativum and Rosa damascena on growing of two kinds of Aspergillus containing as Aspergillus flavus and Aspergillus fumigatus, there will be a hope that in future, by delivering the effective substances of above plants, and doing more experiment and investigation we would be able to reach an acceptable effects and having less side effect and complications for curing fungus infection diseases. Manuscript profile
      • Open Access Article

        2 - The effect of ethanolic and aqueous extracts of Berberies vulgaris on multidrug- resistant gram-negative pathogenic bacteria
        زهرا عطائی کچوئی سیما یحیی آبادی منیر دودی
        Background and Aim: In recent years, due to the indiscriminate and irrational use of synthetic drugs, the resistance of pathogenic microorganisms has increased; therefore, new compounds are vitally needed. The purpose of this study was to investigate the effect of ethan More
        Background and Aim: In recent years, due to the indiscriminate and irrational use of synthetic drugs, the resistance of pathogenic microorganisms has increased; therefore, new compounds are vitally needed. The purpose of this study was to investigate the effect of ethanolic and aqueous extracts of Berberis vulgaris on Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, Citrobacter frundi, Enterobacter aerugenes, Pseudomonas aeruginosa and Acinetobacter baumannii in standard conditions. Material and methods: Ethanolic and aqueous extracts of B. vulgaris were prepared by maceration method. After the bacteria were identified, antibiotic resistance was determined by agar disk diffusion method. Antibacterial effect of ethanolic and aqueous extracts of B. vulgaris on multidrug resistant bacteria was examined at four concentrations of 50, 100, 400 and 800 mg/ml, and (MIC) and (MBC) of these extracts on macro dilution method was also used. The collected data were analyzed using SPSS Software and Kruskal-Wallis and Mann-Whitney tests. Results and Conclusion: The results showed that ethanolic and aqueous extracts of B. vulgaris had an antibacterial effect on a multi-drug-resistant bacteria (MDR). The MIC and MBC of the extracts were reported 50 and 100 mg/ml, respectively. Industrial and practical recommendations: After further investigations, extract B. vulgaris was recommended to be utilized as an alternative to antibiotics for treatment. Manuscript profile