Gholam Reza Bakhshi Khaniki Articles List

List of Articles Gholam Reza Bakhshi Khaniki

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1 - The effects of some ecological factors on essential oil yield and composition of Ziziphora clinopodioides Lam.
غلام رضا بخشی خانیکی فاطمه سفیدکن زینب دهقان

Background & Aim: Different species from mint family (Lamiaceae) are used as spices and fragrance in food or as medicine against viral or microbial diseases in many countries for generation. Lamiaceae family contains 46 genus and 410 species. One of the valuable and More

Background & Aim: Different species from mint family (Lamiaceae) are used as spices and fragrance in food or as medicine against viral or microbial diseases in many countries for generation. Lamiaceae family contains 46 genus and 410 species. One of the valuable and medicinal species of this family is Ziziphora clinopodioides Lam. This species contains the essential oil with pulegone as major compound and used for many medicinal uses.Experimental: In this investigation, the effect of some ecological factors on essential oil content and composition were studied. The aerial parts of Z. clinopodioides were collected at flowering stage from four habitats in Hamedan and Kurdestan provinces. The main parameters from each habitat like altitude, and percentage of slope, soil characters and other plant species were determined. The plant materials were subjected to hydro-distillation in three replications to obtain their essential oils. The essential oils were analyzed by GC and GC/MS.Results & Discussion: The results showed that ecological factors had significant effect (p<0.01) on oil yields. Identification of chemical constituents of the oils showed that main compounds (pulegone and 1, 8-cineole) and minor compounds exist in different percentage in different habitats. So the ecological factors had effect on essential oil composition of Z. clinopodioides. Manuscript profile
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2 - Morphological & anatomical study of Salvia macrosiphon Boiss.
غلام رضا بخشی خانیکی الهام مقسمی

Background & Aim: Salvia macrosiphon is one of the important species of Salvia which belongs to the Lamiaceae family. All 58 Iranian species of Salvia grow in different ecological places. The aim of this research is the investigation of morphological and anatomical More

Background & Aim: Salvia macrosiphon is one of the important species of Salvia which belongs to the Lamiaceae family. All 58 Iranian species of Salvia grow in different ecological places. The aim of this research is the investigation of morphological and anatomical characteristics of S. macrosiphon.Experimental: The above–mentioned species were collected from Zavarijan and Dodangeh region in Borojerd in 2007, and were transferred into a suitable place and then they have been determined systematically and they were used for morphological and anatomical studies by using light microscope.Results & Discussion: The investigation shows the species are mostly similar to the other ones previously studied anatomically. There were many trichomes in epidermal layer of stem. There are also anantomically different bundle sheath in pedicles which is three in middle and two in surrounding area in S. macrosiphon. The collenchyma tissues were observed in corners of stem. Parenchyma cells have chloroplasts and there are also many trichomes in the surface of leaves which seems many of them are secretary.Industrial and practical recommendations: The usage of the extract of different species of Saliva macrosiphon in medicinal and food products and its biological activity totally depends on the chemical compounds of extract. So, according to the importance of these extracts, doing some extensive research on all Iranian species is recommended. Manuscript profile
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3 - Study of un-saturated fatty acids content in Ocimum basilicum L.
غلام رضا بخشی خانیکی

Background & Aim: Ocimum basilicum L. is belong to the Lamiaceae family which is cultivated as a culinary, industrial and medicinal plants in some countries from thousands years ago. The seed of this plant is rich in poly un-saturated fatty acids (PUFA) and produced More

Background & Aim: Ocimum basilicum L. is belong to the Lamiaceae family which is cultivated as a culinary, industrial and medicinal plants in some countries from thousands years ago. The seed of this plant is rich in poly un-saturated fatty acids (PUFA) and produced a large amount of mucilage.Experimental: The oil of seed was extracted separately and converted to fatty acids methyl esters, and composition of fatty acids in seed oil was determined by Gas Chromatography.Results & Discussion: The results show that the highest content of total fat between (A.W.L.P.), (28.98 % of dw) in Ardabil (L.P.) and lowest (17.25 % of dw) in A.G.2 (W.P.). The highest Palmitic acid content is between (A.W.L.P.), (34.81 mol %) in Kermanshah (L.P.) and lowest (2.05 mol %) is in Kerman (L.P.). The highest Stearic acid content is between (A.W.L.P.), (7.56 mol %) in Ahwaz (L.P.) and lowest (1.42 mol %) in Ardabil (W.P.). The highest of Oleic acid between (A.W.L.P.), (22.81 mol %) in Ghom (L.P.) and lowest (11.10 mol %) in A.G.2 (W.P.). The highest Linoleic acid content between (A.W.L.P.), (25.60 mol %) in A.G.1 (L.P.) and lowest (15.55 mol %) in Kermanshah (L.P.). The highest amount of Linolenic acid between (A.W.L.P.), (53.89 mol %) in A.G.1 (W.P.) and lowest (28.08 mol %) in Kermanshah (L.P.). The results also definite clearly that the seed of O. basilicum populations have large amount of un-saturated fatty acids, mucilage and they have a few amount of saturated fatty acids. Manuscript profile
Open Access Article
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4 - Anti-proliferative effect of Trifolium pratense extract on Raji cell line in Burkitt's lymphoma
مرتضی داودی شهریار سعیدیان رضا صغیری زهرا زمانی غلام رضا بخشی خانیکی
10.30495/medherb.2022.693538

Background & Aim: In folk medicine, red clover (Trifolium pratense) use to treat some diseases such as whooping cough, asthma, eczema, and some ophthalmic dysfunction. Due to its phytoestrogens and antioxidant-rich compounds, it is recommended to alleviate some canc More

Background & Aim: In folk medicine, red clover (Trifolium pratense) use to treat some diseases such as whooping cough, asthma, eczema, and some ophthalmic dysfunction. Due to its phytoestrogens and antioxidant-rich compounds, it is recommended to alleviate some cancers. This paper was conducted to study the anti-cancer and apoptosis effects of red clover extract (RCE) on the Raji cell line in Burkitt's lymphoma.Experimental: Red clover lyophilized powder (CAS = 85085-25-2) with a fixed ratio of Formononetin, Biochanin A, Daidzein, and Genistein was acquired from Sigma Aldrich German company. Raji cells were obtained from the Pasteur Institute of Iran-Tehran. Raji cells were treated with different concentrations of RCE, and viable cells were measured at an interval of 24, 48, and 72 hours incubation in three days by MTT assay. Agarose gel electrophoresis was used to determine the DNA degradation. Annexin V-FITC/PI kit and flow cytometry assay were used to determine the percent of apoptotic and necrotic treated Raji cells. Also, expression changes incMYC,ID3, andP53genes were measured by real-time PCR.Results: Red clover extract can prevent in vitro proliferation of the Raji cells in a time and dose-dependent manner. RCE, as well asc-MYCgene suppression and induction ofID3andP53genes, enters the Raji cells in the apoptosis stages with an acceptable percentage and has complication cure potential in Burkitt's lymphoma.Recommended applications/industries: The extract used in this studycombines four components. The individual evaluation effects ofFormononetin, Biochanin A, Daidzein, and Genistein on Raji cells are recommended. Manuscript profile

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List of Articles Gholam Reza Bakhshi Khaniki