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Open Access Article
1 - Effect of polyethylene glycol and propyltrimethoxysilane on structural and optical properties of zinc oxide nanoparticles synthesized by sol–gel process
Djahnit Leila López-González Mar Belhadj Fatima Naitbouda Abddelyamine Benosmane Ali Haddaoui Nacereddine -
Open Access Article
2 - Give a Pattern for Designing Marketing Information System (MkIS) in Tehran Pegah Milk Factories
H. Mehrani A. Sarafizadeh F. HafthangiQuick changes in marketing medium make it more and more necessary for companies to monitor the environment. In fact more competitive conditions would make it necessary for companies to obtain and process the information. To get more and correct informatio MoreQuick changes in marketing medium make it more and more necessary for companies to monitor the environment. In fact more competitive conditions would make it necessary for companies to obtain and process the information. To get more and correct information about inside and outside, companies should use modern technologies and information systems. Marketing information management by technology tools is one of the main and major procedures for applying effective marketing. mar Marketing information systems (MkIS) would help managers through collecting and distribution of marketing information for better and quicker decision making and would led to improvement of efficiency inside the company. In fact MkIS is a supportive system for marketing managers while making any decision. In producing industries especially diary industries, for redundancy of information related to domestic and international markets, competitors and customers and manufactured products, senior and marketing managers need on time, comprehensive and correct information for quick and better decision making proportional to the market conditions and environmental events. As one of the objectives for MkIS is to collect such information, it is necessary for such industries to be equipped with such a comprehensive system. So, this paper is trying to give a correct pattern for designing marketing information system in Tehran Pegah Milk Factories in order to facilitate the process of decision making for senior and marketing managers of this complex. To this end recognition of major information sources, determination of required information for data collection from these sources, finding the new capabilities created in marketing decision making by applying such procedures would be the main objective in this research. Relying on theoretical basis and principals and using experts and managers’ view points in this company, the suitable conceptual model of this research work (Kotler Model) was extracted. This model would show certain parts, determination and evaluation of the required information, collection of information from domestic record of the company, marketing news, marketing researches, decision making supportive system and finally distribution of information. As the view points from relative authorities of Pegah Milk Company in the fields of commercial affairs, marketing, sales and market research are considered for drawing the final pattern for such a system, we discovered information needs and accessible sources for such information through interviews with experts in these sections. Then for testing the results and to determine the relative priorities in terms of the importance of any one, a questionnaire was designed and sent to all relative commercial, marketing, sale and market research authorities of Pegah Milk Company, consisted from such information needs, accessible sources and potentials from using marketing information system. This questionnaire was analyzed in this research as a means of data collection in this research. To analyze data the importance index was used to show the importance of any sources of information needs and statistical clustering analysis was used for their classification with the following results: Determination of the critical sources of the company including domestic and outsourcing, requirement of marketing information of the company and recognizing the potentials created in marketing decision making process for using such marketing information system. Results from the current research are given as a basis for designing the marketing information system of Tehran Pegah Milk Company. Manuscript profile -
Open Access Article
3 - Assessment of the Function of the Health, Safety and Environmental Management System (HSE) in the Dry Milk Factory of Pegah Shahr E Kord with the Balanced Scorecard Approach
Rouhollah Molavi Vardanjani Maryam Rafati Mojgan ZaeimdarBackground and Objectives: Functional evaluation models are the basis for measuring and improving management systems. The purpose of this research was to meet the needs of dry milk factory in Pegah Shahr E Kord to assess the performance of the HSE system in terms of com MoreBackground and Objectives: Functional evaluation models are the basis for measuring and improving management systems. The purpose of this research was to meet the needs of dry milk factory in Pegah Shahr E Kord to assess the performance of the HSE system in terms of compliance considering the company's strategies. Methodology and Materials: In this research, with close investigation on standards and models in the field of performance of the HSE management system, the functional evaluation model of this factory was designed in the framework of a Balanced Scorecard Card (BSC). In this model, four layers of Financial, Customer, Internal business processes and Learning- growth were identified and classified with 14 function evaluation criteria and 43 sub-indicators. Results: The results of the balanced scorecard model showed that the highest and lowest scores among the studied layers were internal processes with an average of 69.28 and learning-growth with an average of 56.66 respectively. Also, the overall average score of the company in all four layers calculated 64.2 out of 100 which, according to a standard score, the scores over 60, reflects the relatively good Function of the organization in the field of HSE management. Conclusion: According to the results, Value Indicators presentable for Customers, Audit and Improvement of HSE Performance Indicators, Policy Development and Strategic goals, organization and provision of resources for HSE management, risk management for HSE, system planning and designing in order to establish the principles of HSE in the organization, are the most important strengths and information sources, also human capital and presentable value to society and government are the most important improvable parts of the HSE system in studied organization. Manuscript profile -
Open Access Article
4 - Predicting of Equity Premium: Empirical Evidence from PEG Models
Ali Rahmani Mohammad Tasharofi Ali Saghafi Saber SheriPricing of financial assets and identify important risk factors is one of the fundamental issues of finance theory. In this study, using insights of CAPM and three-factor model (Fama and French, 1993), PEG and four-factor models was developed. Using financial data of 27 MorePricing of financial assets and identify important risk factors is one of the fundamental issues of finance theory. In this study, using insights of CAPM and three-factor model (Fama and French, 1993), PEG and four-factor models was developed. Using financial data of 270 companies traded in TSE during the beginning of 2006 to the end of 2014, three-stage methodology and the portfolio study methodology used to calculate the risk factor. The results show that first, there are inverse size effects, inverse value effects and PEG effects, second, PEG model cannot explain stock risk premium, But the four-factor model compared with other models, has higher power for explaining of the risk premium. Market participants can use these results to improve investment performance and academics recommended that test models of the study. Manuscript profile -
Open Access Article
5 - Study effect of methanolic extract of Peganum Harmala and Harmine on Kidney tissue damage of diabetes mellitus in male Wistar rats
Forough Kajbaf Shahrbanoo Oryan Ramesh Ahmadi Akram EidiIntroduction: The dangerous side effects of diabetes are diabetic nephropathy, which has a relatively high prevalence in diabetic patients and causes renal failure. Investigating the process of destruction and the mechanisms that prevent it, in order to reduce the tissu MoreIntroduction: The dangerous side effects of diabetes are diabetic nephropathy, which has a relatively high prevalence in diabetic patients and causes renal failure. Investigating the process of destruction and the mechanisms that prevent it, in order to reduce the tissue damage, especially with the treatment of plants, can be a significant issue. Material and methods: In this research, Espand with scientific name of Peganum harmala, a plant of the Zygophyllaceae family and its effective substance called harmine in diabetes-induced renal injury, were studied on 80 male Wistar rats in experimental and diabetic groups. Rats were treated with methanolic extract of seeds and leaves of Peganum Harmala and Harmine. After tissue passage and fixation, Microscopic slides were prepared and studied. In tissue studies, four factors of epithelial changes, tubular destruction, leukocyte inflammation and capillary obstruction were detected in the kidneys. Results: The diabetic rat group received harmine and the diabetic rats receiving the extract of the seed were less damaged, while in the diabetic rats recieveing the leaf extract these lesions was higher and it was interesting to note that there was no difference in the experimental groups with the positive control group. Conclusion: According to the tissue results in our study, seed extract and harmine have the ability to prevent tissue damage caused by diabetes, which can be attributed to the harmine alkaloid in the seed. Manuscript profile -
Open Access Article
6 - Provide steganography using the recursive method in JPEG images
seyed ali akbar hashemi Alireza Malahzadeh Hamid Dehghani Increasing communication through digital media has made the issue of security very important. Steganography is a way to hide communication through cover media. Hiding information in JPEG images is very attractive because these types of images are the most widely u More Increasing communication through digital media has made the issue of security very important. Steganography is a way to hide communication through cover media. Hiding information in JPEG images is very attractive because these types of images are the most widely used images on the Internet. There are many ways to detect the presence of hidden information in JPEG format, which are also very accurate, and so far there is no method that can be called secure. Due to the loss of JPEG compression and the effects that this type of compression has on images, it has become impossible to use the spatial field for embedding easily. Embedding in the DCT coefficients of the JPEG algorithm has also been discovered in any of the proposed methods. This paper presents a recursive method for embedding in the conversion domain before JPEG compression, which uses blocking other than the usual JPEG blocking. Embedding is done in such a way that JPEG compression does not cause any errors when extracting data. These properties make the security and capacity of the method good. Manuscript profile -
Open Access Article
7 - A novel face images compression scheme using sparse signal representation and RLS_DLA dictionary learning algorithm
Amir Masoud Taheri Homayoun Mahdavi-NasabDue to the rapid growth of information technology and exponential increasing of information the need for more and more storage capacity and efficiency has increased. Image compression is an important tool to reduce the redundancy of images data in order to be able to st MoreDue to the rapid growth of information technology and exponential increasing of information the need for more and more storage capacity and efficiency has increased. Image compression is an important tool to reduce the redundancy of images data in order to be able to store or transmit them in an efficient manner. When images are limited to a specific and limited family of images like MRI databases of a hospital or facial image database of a university or an organization or fingerprint image databases, this limitation increases the total spatial redundancy. Thus, efficient storage of such images is beneficial, and their compression becomes an appealing application, and this urges algorithms specially tailored for the task of content base image compression to surpass general purpose compression algorithms. The facial images, due to their wide application as the most common images in the organizations and companies are more considerable for image compression. In this paper a new image compression scheme using sparse coding and RLS-DLA redundant dictionary learning is proposed that can be used for compressing of face image databases. In the proposed method, several dictionaries are exploited adaptively based on the required image quality to enhance the overall rate-distortion. The simulation results show that this scheme outperforms the state-of-art algorithms like JPEG2000 by about 0.5 to 1.2 dB for reconstructed images PSNR. Manuscript profile -
Open Access Article
8 - A Novel protocol for synthesis of Hantzsch 1, 4- dihydropyridines using PEG-400 as a reaction medium and under catalyst-free condition
Ali Ezabadi Fatemeh Tosan -
Open Access Article
9 - Novel procedure for preparation of Hantzsch 1, 4- dihydropyridines using PEG-400 as a reaction medium and under catalyst-free condition
Ali Ezabadi Fatemeh Tosan -
Open Access Article
10 - Investigating the factors affecting customers' satisfaction with Pegah dairy products
Fahimeh khosravani Azita Zand Behrooz Saraie Ali Ebrahimi -
Open Access Article
11 - A comparative view of the mystery of wealth and happiness in Shahnameh and Haft Peykar
leyla ساعی naser naseri shahriyar hasanzadehn a comparative and analytical study of the happiness of the wealthy princes in Shahnameh and Haft Peykar, we find out how they use national mirrors and beliefs and archetypes and religious orders such as benevolence and charity day by day. They prospered and perpetuate Moren a comparative and analytical study of the happiness of the wealthy princes in Shahnameh and Haft Peykar, we find out how they use national mirrors and beliefs and archetypes and religious orders such as benevolence and charity day by day. They prospered and perpetuated their rule and increased their happiness and enjoyment of divine blessings by giving, giving, forgiving, and spreading the word to the general public, and by holding popular, national, and religious celebrations. The kings, who had a stable government and a prosperous life, praised their Lord in the mornings and evenings, and honored the wise, the clergy, and the astronomers, and consulted with them in carrying out and ending serious matters. The results of the research show that elements such as having a divine spirit and good looks of the rulers, having physical ability and bravery, greed, prayer, benevolence, using music, have been the factors of wealth and happiness of the Iranian princes. In some cases, Ferdowsi and in some issues, Nezami have taken a deeper look at them, and in the pages of this article, several examples have been studied. Manuscript profile -
Open Access Article
12 - In vitro assessment of antimicrobial effect of methanolic extract of Peganum harmala against some important foodborne bacterial pathogens
طیبه zeinali محمد Mohsenzadeh رویا Rezaeian-Doloei رویا NabipourFoodborne bacterial pathogens play an important role in food infections/intoxications in human population. With ever increasing the number of antibiotic-resistant bacterial strains, there is an attempt to use the antimicrobial properties of herbs. Peganum harmala is a m MoreFoodborne bacterial pathogens play an important role in food infections/intoxications in human population. With ever increasing the number of antibiotic-resistant bacterial strains, there is an attempt to use the antimicrobial properties of herbs. Peganum harmala is a medicinal plant of Iraniantraditional medicine which was used as an antiseptic in the past. Amongthe foodborne bacterial pathogens, Escherichia coli O157:H7, Salmonella Typhimurium and Listeria monocytogenes are considered as the most important and hazardous pathogens. The aim of this study was to evaluate the antibacterial effect of methanolic extract of Peganum harmala against these bacteria in vitro. The minimum inhibitory concentration (MIC) and minimum bactericidal concentrations (MBC) of methanolic extract of Peganum harmala was determined against three foodborne bacterial pathogens by micro-dilution method in Muller-Hinton broth. According to the results, MIC for E. coli O157:H7 and S. Typhimurium was 1.56 mg/ml. In the case of L. monocytogenes, it was estimated at 0.78 mg/ml. Moreover, results revealed that MBC for these organisms was similar to MIC concentrations. Regarding the results, Peganum harmala can be used as an ingredient in the formula of the disinfectants applied in the food systems. Manuscript profile -
Open Access Article
13 - Antibacterial activities of the ultrasound assisted extracts of Laurus nobilis, Peganum harmala and rosemary
M. Ghorbanpour H. JahediThe present study was aimed to investigate the antibacterial activities of the Laurus nobilis,Peganumharmala and rosemary extracts against Staphylococcus aureus and Escherichia coli. Thus, the ultrasonic extracts were performed using the aqueous, ethanol, hydro-alcoholi MoreThe present study was aimed to investigate the antibacterial activities of the Laurus nobilis,Peganumharmala and rosemary extracts against Staphylococcus aureus and Escherichia coli. Thus, the ultrasonic extracts were performed using the aqueous, ethanol, hydro-alcoholic or chloroform phases. The microdilution technique was used to evaluate the antibacterial activities which was finally reported as the MIC and MBC values. All the extracts showed the antibacterial activities against the bacteria at the concentration of 6.25%. However, the metalonic extract exert a maximum antibacterial activity. The extract of three plants revealed the same antibacterial activity against E. coli, but the ethanoloic extract from P. harmala showed a maximum antibacterial activity against S. aureus at the concentration of 6.25%. Results of the current study showed the similar antibacterial activities of the extracts against E. coli; meanwhile, the maximum antibacterial effect on S. aureus was observed by applying alcohol or water as a solvent. In general, this paper proposed that ultrasound assisted extraction was quick and cost effective approach to extract the plants. In addition, ethanolic solvent was found as the best selection among the aqueous, hydro-alcoholic or chloroform solvents. Manuscript profile -
Open Access Article
14 - برهم کنش عصاره جلبک دریایی (Ascophyllum nodosum) و تنش خشکی بر شاخصهای جوانهزنی بذر گیاه گوجهفرنگی(Lycopersicon sculentum L.)
راهله احمدپور فرنوش محمدی نظام آرمند -
Open Access Article
15 - Antibacterial survey of different extracts of Peganum harmala L. different parts in North east of Golestan province (Inche Borun)
معصومه Mazandarani E.A Ghaemi فاطمه GhaffariPeganum harmala L. belongs to Zigophyllaceae family is one of the most important medicine plants with wild distribution in stepic and semi stepic of Golestan province. In this research, after phenology ethnopharmacological data obtained from turkman rural people. Differ MorePeganum harmala L. belongs to Zigophyllaceae family is one of the most important medicine plants with wild distribution in stepic and semi stepic of Golestan province. In this research, after phenology ethnopharmacological data obtained from turkman rural people. Different parts of plant were collected in May to late of September 2008 in dry stepic region of North east of Golestan province (Inche Borun). Aqueous, infusion and ethanolic extract were obtained by percolation method and their antibacterial effect was evaluated by disc diffusion and well methods. Inhibition zone after 24h incubation of 37 and their antibacterial activity were assessed by Pearson chi-square (P<0.05). Ethnopharmacological data in this research showed, it has been used by the Turkmen rural healers in North east of Golestan province as strong anti air infection, sedative, anti bacterial and skin inflammation to treatment fungal, gastro intestinal infection and dysmenorrhea. Ethanol extracts of root and seeds had the most efficacy against tested bacteria, especially in well method (P<0.001), another extracts had no any antibacterial effect. 78.8% of gram positive and negative bacteria (Bacillus licheniformis, Staphylococcus epidermisis, Staphylococcus aureus, Micrococcus loteus, Salmonella typhi, Shigella dysentria) were the most sensitive bacteria against ethanol extract, but gram negative bacteria such as Pseudomonas aeroginosa and Proteus loteus were the most resistant bacteria (P<0.001). Rural people were interested to take seed and smok for air disinfection, sedative and calming, can be a good candid for chemical analysis of antibacterial activity in animal and clinical models for formulation and production of natural antibacterial drug. Manuscript profile -
Open Access Article
16 - Investigation of the stability of PEG stearate-coated Chitosan nanoparticles loaded with levothyroxine
Elham Rostami -
Open Access Article
17 - Synthetic Application of Magnetic Nanocomposite Fe3O4@PEG-Au as a Heterogeneous and Reusable Nanocatalyst in The Suzuki Coupling Reactions
Amir Homayoun Keihan Hamed Veisi Hadis Javaheri -
Open Access Article
18 - Investigation of the stability of PEG stearate-coated Chitosan nanoparticles loaded with levothyroxine
Elham Rostami -
Open Access Article
19 - Evaluation of Survival and Risk Probability of Exchange Regimes in Economies having Exchange Anchor Monetary System and Inflation Targeting - Duration Model Approach
AliReza Kazerooni Hosein asgharpour Majid FeshariThe main objective of this paper is to investigate the survival and risk probability of pegged and floating exchange rate regimes in different countries: those having exchange rate anchor versus those having inflation targeting monetary regimes during 1999-2010. In orde MoreThe main objective of this paper is to investigate the survival and risk probability of pegged and floating exchange rate regimes in different countries: those having exchange rate anchor versus those having inflation targeting monetary regimes during 1999-2010. In order to achieve the goal, Duration Model Approach will be used to represent the survival and risk analysis of pegged and floating exchange rate regimes. The empirical findings of this paper suggest that, in two groups of countries, the floating exchange rate is a credible regime and it has a lower risk and then higher survival probability. Manuscript profile -
Open Access Article
20 - A Novel Video Compression Algorithm Using Wavelet Transform and neural network
Mohammad Rahmanian Ahmad Hatam Mohammad Ali ShafieeianVideos are made up of a temporal sequence of frames and are projected at a proper rate to create the illusion of motion. This means that there exists a high correlation between adjacent temporal frames so that when projected at a proper rate, smooth motion is seen. Corr MoreVideos are made up of a temporal sequence of frames and are projected at a proper rate to create the illusion of motion. This means that there exists a high correlation between adjacent temporal frames so that when projected at a proper rate, smooth motion is seen. Correlation between adjacent temporal frames is called interframe correlation. In order to decode compressed video bit stream uniformly by various platforms and devices, the bit stream format must be predefined. Thus, there must be a standard for a video compressor, which will enable all standard-compliant compressed video data to be decoded anywhere. The goal is to propose a new video compression algorithm based on wavelet transform and neural networks. Using wavelet transform leads to factorization in temporal as well as spatial domain. The goal in this paper is to achieve a compression algorithm which would be faster and has more compression ratio. Neural networks are used for prediction which is one of the most important functions in any video compression scheme. Furthermore, the proposed algorithm is compared with MPEG standard. Simulation results show the befits of using wavelet transform which reveal that the proposed algorithm is faster and has better performance in some aspects compared to MPEG standard. The video which obtained from proposed algorithm has acceptable in human visual and since it needs less than space for storing, it is suitable for portable devices. Manuscript profile -
Open Access Article
21 - برهم کنش عصاره جلبک دریایی (Ascophyllum nodosum) و تنش خشکی بر شاخصهای جوانهزنی بذر گیاه گوجهفرنگی(Lycopersicon sculentum L.)
راهله احمدپور فرنوش محمدی نظام آرمند -
Open Access Article
22 - The Survey of anticancer and anti Microbial properties of Rosmarinus officinalis L, Peganum harmala L and Coffee Extracts on cell viability of Cancer cells and Pathogenic Bacteria in Foods
Ali Sharifzadeh faranak aali sayeh vahhabiDespite significant advances in radiation therapy and cancer treatments in the past 30 years, resistance to chemotherapy is a major obstacle in the recovery of patients with cancer. Resistance to chemotherapy drugs inhibits the recovery process. This study aims to evalu MoreDespite significant advances in radiation therapy and cancer treatments in the past 30 years, resistance to chemotherapy is a major obstacle in the recovery of patients with cancer. Resistance to chemotherapy drugs inhibits the recovery process. This study aims to evaluate the anticancer activity of the hydroalcolic extracts of Rosemary, Peganum and Coffee on growth inhibition of MCF-7 cell line and determine the rate of growth inhibition of pathogenic bacteria isolated from food.We examined cytotoxicity effects of three different concentrations (60,120,250 μg/ml) of Rosemary, Peganum and Coffee extracts on MCF-7and HDF cell lines. . The standard MTT assay was performed to estimate cell viability after treatment by Rosemary, Peganum and Coffee extracts. The extracts were also used with MIC on Staphylococcus aureus and E. coli bacteria isolated from food.The results of the MTT assay showed that the Rosemary, Peganum and Coffee extracts had time-and concentration-dependent anticancer activities on the MCF-7cell line compared to HDF cells statistically significant (p Manuscript profile -
Open Access Article
23 - Effects of Artemisia sieberi extract on growth and nutrients uptake of Peganum harmala
Asma Ricki Maryshany Mahdieh Ebrahimi Ebrahim Shirmohammadi -
Open Access Article
24 - The responses of potato cultivars to osmotic and temperature stresses under in vitro conditions
Farnoosh Jafari Jaber Panahandeh Alireza Motallebi Azar Mousa Torabi Giglou -
Open Access Article
25 - PEG imposed water deficit and physiological alterations in hydroponic cabbage .
Sunaina , Nimisha Amist Amist Narsingh Bahadur Singh Singh -
Open Access Article
26 - Comparison of the effects of harmala seed powder and salinomycin coccidiostate on the performance and extent of OPG in broiler chicks
Majid Goodarzi farid NasrollahiTo assess and compare of the effect of harmala seed with coccidiostat on broiler performance and OPG was performed an experiment in a completely randomized design with four treatments and four replications for each treatment. 192 day-old chicks (Ross 308) were randomly MoreTo assess and compare of the effect of harmala seed with coccidiostat on broiler performance and OPG was performed an experiment in a completely randomized design with four treatments and four replications for each treatment. 192 day-old chicks (Ross 308) were randomly assigned to four treatments. The diets included basal diet as control, the diet containing 200 grams per tonne coccidiostate Salinomycine (12%) and the diets containing 0.2 % and 0.4% harmala seed powder. The results showed significant positive impact (p< 0.05) of coccidiostatic and 0.2% harmala seed on functional traits. The highest daily weight gain (51 gr), body weight (2180 gr) and feed intake (95.87 g) were related to the dite contain coccidiostat. Harmala seed at 0.2 percent level also increased live weight and improved FCR. The minimum FCR (1.82) was related to 0.2% harmala Group. The using of 0.4% harmala seed and coccidiostat decrease the number of OPG on 30 days of age. The results of this experiment showed that 0.2% harmala seed powder has a positive effect on performance parameters and 0.4% of it decreased the number of OPG. Because of the negative impact of 0.4% level on performance parameters, it can not be recommended for this purpose. Manuscript profile -
Open Access Article
27 - Evaluation the effects of drought Stress Induced by Polyethylene glycol on germination and seedling growth of maize hybrids
Mohammad Moradi Ahmad Hasnaki Fard Mohammad MotamediWater deficit is a common and major constrain for agricultural production in arid and semi-arid parts of the world like Iran, to the extent that it might threaten the nation’s food security in years to come. Seed germination is a crucial growth stage that is often MoreWater deficit is a common and major constrain for agricultural production in arid and semi-arid parts of the world like Iran, to the extent that it might threaten the nation’s food security in years to come. Seed germination is a crucial growth stage that is often affected by environmental stresses, including drought. This study investigated the effects of four levels of water osmotic potential (i.e. 0, -3, -6 and -9 bar) on germination and seedling characteristics, of three maize hybrids )SC500, SC640 and SC704). According to the results, different levels of drought stress, type of cultivar and intraction beatween them had significant effect on measured characteristics. Results also showed that significant decrease was observed in the percentage and rate of germination, radicule and plumule of long and weight and seedling total dry matter. SC500 as a drought-tolerant hybrid, indicated the greatest germination percentage radicle and plumule length, radicle and plumule dry weight than the other cultivars. So, this hybrid was more tolerance to water stress. Manuscript profile -
Open Access Article
28 - Preparation and characterization of biodegradable magnetic nanoparticles biodegradable based on polyurethane for gene delivery into MCF-7 cells
Zhale Alirezazad hashem yaghoubi Somayeh Javid Zahra AjamThe folate receptor (FR) is known to be over-expressed extracellularly on a variety of human cancers. Therefore, this molecule is an ideal candidate for targeting nanoparticles to drug delivery using these nanoparticles to cancer cells or cancer tissues. In this study, MoreThe folate receptor (FR) is known to be over-expressed extracellularly on a variety of human cancers. Therefore, this molecule is an ideal candidate for targeting nanoparticles to drug delivery using these nanoparticles to cancer cells or cancer tissues. In this study, we designed an amphiphilic cationic Fe3O4-PEI-PU-PEG-FA nanoparticles. The prepared nanoparticles were characterized by FTIR, VSM, TEM measurements. FTIR indicated that the synthesis of Fe3O4-PEI-PU-PEG-FA nanoparticles have been performed successfully. Vibrating sample magnetometry (VSM) showed that the biodegradable-magnetic nanoparticles were superparamagnetic at room temperature. The morphology of the Fe3O4 and Fe3O4-PEI-PU-PEG-FA nanoparticles were evaluated using a transmission electron microscopy. TEM showed the nanoparticles were spherical in shape. Moreover biocompatibility assay of Fe3O4-PEI-PU-PEG-FA nanoparticles was performed using MTT test. Also the ability of Fe3O4-PEI-PU-PEG-FA nanoparticles to DNA delivery into MCF-7 cells were analysis using MTT test and flow cytometry respectively. Interestingly, due to the incorporation of PU and PEG segments, this Fe3O4-PEI-PU-PEG-FA nanoparticles showed less toxicity but better gene transfection efficiency than PEI. Manuscript profile -
Open Access Article
29 - PEGylation of polyamidoamine-G3 dendrimer bonded with silica-coated magnetic nanoparticles as a pH-sensitive targeted drug delivery system
seyed esmaeil mhamadi mehr Mehdi Faramarzi seyed abotaleb mosavi parsaThis research, reports the fabrication of a new pH-responsive nanocarrier based on iron oxide nanoparticle with dendrimer coating and PEG conjugated for targeted and controlled delivery of chemotherapy drugs to cancer cells. The structure of the nanocarrier was confirme MoreThis research, reports the fabrication of a new pH-responsive nanocarrier based on iron oxide nanoparticle with dendrimer coating and PEG conjugated for targeted and controlled delivery of chemotherapy drugs to cancer cells. The structure of the nanocarrier was confirmed by Fourier transform infrared (FT-IR) spectra analysis. transmission electron microscope (TEM), Field Emission Scanning Electron Microscopy (FE-SEM) and vibrating sample magnetometer (VSM) analysis showed that the nanocarrier has a spherical structure with super paramagnetic properties. The efficiency of nanocarrier was evaluated with cyclophosphamide chemotherapy drug. The in vitro drug release studies at different pH proved the pH-sensitivity of the nanocarrier. Due to the open state of dendritic structure in acidic pH, the maximum release observed at pH 4.5 (lysosomal pH). Mass transfer studies showed that drug release from nanocarrier is rapid in short contact time and slow in long contact time. These results indicate that cyclophosphamide-loaded magnetic nanocarrier is promising for targeted delivery and controlled drug release. Manuscript profile -
Open Access Article
30 - Vanadium cross-linked CMC-PEG-PLGA based on nanocomposite hydrogel with sodium alginate coating as a pH-sensitive insulin delivery system
Seyyed Nabiollah Hosseini Asieh Abbassi Dolavi Seyed Javad Zia-e-Haq Ayyub Saeedi: In recent years, significant advances have been made in the use of biomedical polymers as targeted carriers for the release of drugs, proteins, and growth factors. Vanadium (V) nanocomposite hydrogels were prepared in this study due to the formation of vanadium nanopa More: In recent years, significant advances have been made in the use of biomedical polymers as targeted carriers for the release of drugs, proteins, and growth factors. Vanadium (V) nanocomposite hydrogels were prepared in this study due to the formation of vanadium nanoparticles inside the swollen CMC hydrogels. The formation of vanadium (V) nanoparticles in hydrogels has been studied using Fourier transform infrared spectroscopy (FTIR), X-ray diffraction patterns (XRD), scanning electron microscopy (SEM) experimental techniques. The XRD patterns analysis confirmed the formation of vanadium nanoparticles in a hydrogel matrix, and scanning electron microscopy micrographs also showed that the size of the nanoparticles was from 22 to 74 nm in the hydrogel matrix. The swelling behavior of nanocomposite hydrogels was studied at pH of 2.1 and 7.4. Hydrogels have shown better water absorption in less pH. Fourier transform infrared spectroscopy indicates the interaction between polysaccharides and the samples taken from the drug indicate that the drug-loaded peaks were loaded appropriately. With the release of drug from nanocomposite and pure hydrogel hydrogels, it was observed that its release rate in nanocomposite hydrogels was lower and the amount of its release decreased with increasing percentage of nanoparticles. In the cytotoxicity test after 24 h, the cell viability was in the range of 74.35% -96.05% (compared with the control sample, which was 100%). In the hydrogel nanocomposite sample containing insulin had the lowest cell viability of insulin 31.25 μg/ml after 24 h and it had the highest cell viability at 1000 (μg/ml) concentration with 25.7% cell cytotoxicity compared to the control group. Manuscript profile -
Open Access Article
31 - The Myth of Blood and Its Ritual Functions in the Stories of Shāhnāmeh
Hasan Heidary Mozhgān Sādeghpour MobārakehOld rituals are associated with mythology, which means that man has lived with myth from the beginning. Human beings have common concepts such as suffering, happiness, war, peace, love and other emotions that open to a common sense and bring together single people; so t MoreOld rituals are associated with mythology, which means that man has lived with myth from the beginning. Human beings have common concepts such as suffering, happiness, war, peace, love and other emotions that open to a common sense and bring together single people; so they give meaning to myths and rituals. Blood is a part of human biological existence and his/her stream of life that goes beyond the body, becomes a common concept among humans and is the source of many myths and ancient rituals in the personal and social life of mankind. The myth of blood is manifested among various nations in various forms. Among Iranian people, the myth has many faces which some of them, such as shedding blood and drinking it, are appeared in Shāhnāmeh, the national Iranian epic. By using an analytical-comparative approach and based on evidence from other cultures, the present essay attempts to study the myth of blood and its ritual functions in the stories of Shāhnāmeh. The result of the research shows that the myth has a ritual function in forms of scapegoating, repelling evil, seeking revenge, mourning and Anew life. Manuscript profile -
Open Access Article
32 - A Critical Review of René Girard’s Mythology Theory
Masood Algooneh JunqaniRené Girard takes a critical approach to the James George Frazer and Claude Lévi-Strauss anthropological views. He belongs to the Freudian psychoanalytic school and the late French psychoanalysis. Girard has proposed a view about history and culture that i MoreRené Girard takes a critical approach to the James George Frazer and Claude Lévi-Strauss anthropological views. He belongs to the Freudian psychoanalytic school and the late French psychoanalysis. Girard has proposed a view about history and culture that is a novel mixture of literary criticism, mythology, psychoanalysis and religious studies. He puts forward the idea that in every myth it can be found the trace of a real violence that has changed over time; he turns to a Euhemeristic mythological point of view which holds that objective historical violence is a constitutive component of rituals and myths of different tribes. By reading texts, he identifies symbolic signs that indicate to mimetic desire in human’s ontological and psychological structure as well as victimary process and scapegoat mechanism in the cultural foundations of different ethnic groups. Accordingly, the present article attempts to consider the origins of Girard's ideas and his arguments by using analytical-critical method. The author of the paper puts an emphasis on Girard's irrationalist points of view and criticizes his anti-Cartesian views about the "subject". Also, what he proposes as the foundation of human culture follows a blind and wild unconsciousness which is based on denial of self-conscious position of desire. Manuscript profile -
Open Access Article
33 - The Ritual of Scapegoating in Hadiqat al Haqiqa of Sanāī; A Mythological Analysis
zahra baratieh Qorbānali Ebrāhimi Mehrdād ChatrāeeScapegoating is one of the religious-mythical rituals, having been long common among different tribes and nations for various purposes. Many of the mythological and ancient traditions have suggested different ways of scapegoating to stay away from disaster or to abolish MoreScapegoating is one of the religious-mythical rituals, having been long common among different tribes and nations for various purposes. Many of the mythological and ancient traditions have suggested different ways of scapegoating to stay away from disaster or to abolish it. In classic Persian literature, Sanāī has been named as one of the first innovators who spread the mystical and philosophical and didactic teachings. As evidenced by the great number poems of Hadiqat al Haqiqa, Sanāī is very familiar with the myths and has well made use of the popular culture of his day. By employing descriptive-analytical and library methods, in the present study, we attempt to show that Sanāī took into consideration various forms of scapegoating - including sacrificing, writing amulet, burning peganum harmala (esfand) - in Hadiqat al Haqiqa. To clarify the matter, after analyzing the doctrine of scapegoating and the related rituals, we examine the cases found in Hadiqat al Haqiqa. The findings of the research indicate that Sanāī has been fully familiar with the rituals of scapegoating and used them in the most artistic way possible in Masnavi of Hadiqat al Haqiqa. Manuscript profile -
Open Access Article
34 - Removing Pain: The Reflection of a Mythological Ritual in the Mystical Texts of Naqshbandiyah
Seyyed Mohsen Hosseini MoaekherOne of the thaumaturgical powers that can be found in Sufi texts is healing, which has manifested itself in different ways. It seems that "removing pain" is a remnant of a mythological ritual that mythologists have referred to it as “apotropaic magic” or sca MoreOne of the thaumaturgical powers that can be found in Sufi texts is healing, which has manifested itself in different ways. It seems that "removing pain" is a remnant of a mythological ritual that mythologists have referred to it as “apotropaic magic” or scapegoating. The mythological scapegoats were mainly aimed at driving away disease, effects of sin, calamity, famine and drought, and, in general, any evil. One of the uses of these scapegoatings was to drive the disease out of the patient. Accordingly, the scapegoat transmits the disease to himself/herself and thus heals the sick person. In some Sufi texts, this form of healing is seen as a miracle performed by a mystic. By using analytical-descriptive method, the present research examines the miracle of "removing pain" in the mystical texts of Naqshbandiyah and compares it with mythological rituals, and then some examples of the ritual are introduced. The results indicate that the texts of the Naqshbandiyah are more influenced by this mythological belief than other Sufi texts. Manuscript profile -
Open Access Article
35 - Filgrastim Versus Pegfilgrastim for Neutropenia Prevention in Children with Solid Tumors: A Randomized Trial
Aziz Eghbali Maryam Behtash Roghayyeh Rahimi Afzal Aygin Eghbali Bahar Taherkhanchi Bahador Bagheri -
Open Access Article
36 - Determination of Seizure Threshold due to Intrapritoneal Injection of Harmaline in NMRI Mice
غلامحسن واعظی مهسا ترابی عبدالحسین شیرویHarmaline is one of the alkaloids that exist in different plant like Peganum harmala. This alkaloid has stimulative effect on realasing serotonin and katkol -amins in different parts of the brain.Also this alkaloid has hallucinogenic effect. one of the most important ph MoreHarmaline is one of the alkaloids that exist in different plant like Peganum harmala. This alkaloid has stimulative effect on realasing serotonin and katkol -amins in different parts of the brain.Also this alkaloid has hallucinogenic effect. one of the most important pharmacological effects of Harmaline is the inhibitory effect on Monoamine oxidase enzyme.Also Harmaline with attachment to Inverse agonist locus GABA-A receptors produced a wide range of antagonistic effects against benzodiazepins and interference of benzodiazepine receptors in produce seizure and tremor has show.This research has done to estimate seizure threshold due to intrapritoneal injection of Harmaline in comparison with seizure threshold pentylenetetrazole (PTZ) of male NMRI mice.In this research the positive control receive of amount 45mg/kg,ip of PTZ and the other groups were injected with 5,10,20 mg/kg,ip of Harmaline.After above injections, seizure symptom has been estimated.As result of this research indicate the seizure threshold in positive group (PTZ) is amount 45mg/kg and seizure threshold of Harmaline is amount 5 mg/kg.In conclusion can reveal that Harmaline with attachment to Inverse agonist locus GABA-A receptors produced a wide range of antagonistic effects against benzodiazepins and has show that gabaergic system and serotonin neurotransmitters are involved in seizure activity due to Harmaline.While in seizure due to PTZ,interfere picrotoxine locus of GABA receptor and benzodiazepine locus has partial role on its effects.The result of this research has been shown that Harmaline reduce seizure threshold dose dependent significantly. Manuscript profile -
Open Access Article
37 - Effect of micronutrient elements on germination and seedling characteristics in sugar beet under drought stress conditions
masomeh nasiri raouf ssharifiSeeds that grow in root and stem conditions under drought conditions can be found more quickly and quickly, and in poor environmental conditions, they guarantee higher yields. The experiment was a factorial experiment with completely randomized design with three replica MoreSeeds that grow in root and stem conditions under drought conditions can be found more quickly and quickly, and in poor environmental conditions, they guarantee higher yields. The experiment was a factorial experiment with completely randomized design with three replications. The investigated factors were 8 levels of fertilizer treatment 1. Control (no spraying) 2. Pure iron (2 per thousand) 3. Pure manganese (2 per thousand) 4. Pure boron (2 per thousand) 5. Boron and manganese (4 In thousand) 6. Iron and boron (4 per thousand) 7. Iron and manganese (4 per thousand) 8. Manganese and boron (6,000) and five osmotic potential levels (0, 2-, 4-, 6-, 8-). Polyethylene glycol 6000 was used to create various osmotic potentials. With the occurrence of osmotic stress, germination speed, germination uniformity, germination percentage and traits related to root and shoot dry weight, root length and shoot length decreased significantly. Germination percentage is related to root length. The roots become green before other plant organs come out of the seed. Consequently, they are subjected to environmental stress before other organs. Therefore, root length trait is a suitable criterion for choosing drought tolerance. The highest root length was obtained in manganese and the least in iron treatment with manganese. Figures with more germination percentage, seedlings longer and more dry matter. Manuscript profile -
Open Access Article
38 - Effect of temperature, drought and salinity stresses on germination of ten medicinal plant seeds
Mehrab Yadegari Abdollah GhasemiTo study the effects of salinity, temperature and drought stresses on germination indices in seeds of alyssum, dill, borage, marigold, saint john's wort, lemon balm, purslane, feverfew, thyme, and fenugreek, factorial experiments in laboratory conditions were performed MoreTo study the effects of salinity, temperature and drought stresses on germination indices in seeds of alyssum, dill, borage, marigold, saint john's wort, lemon balm, purslane, feverfew, thyme, and fenugreek, factorial experiments in laboratory conditions were performed in laboratory conditions in completely randomized design with 4 replication. The treatments contained of salinity at 4 NaCl concentrations (0, 0.25, 0.5, 0.75 mM), Drought (PEG in 0, -0.6, -0.9, -1.2 bar) and Temperature (10/20, 15/25, 20/30, 25/35 °C night/day). The results showed that the treatments had significant effect on germination indices. By comparisons between species, the greatest seed vigour and germination percentage were made in seeds of purslane, then purslane seeds were the most tolerant to drought and salinity and other hand, the seeds of lemon balm and thyme in most of measured characters had the minimum values. By increasing salinity and drought levels, root dry/fresh weight, stem dry/fresh weight, root/stem length and vigour of seeds were decreased in all species. Germination percentage was increased by higher level of temperature but decreased by upper levels of salinity and drought stresses. The highest seed vigour was made in temperature of 20/30°C night/day and no salinity and drought stress (control) and the least related to the temperature degrees of 10/20°C night/day and concentration of 0.75 mM of NaCl and -1.2 bar of PEG. Then the seed of plants for example purslane can introduce for planting in salinity and drought regions, and seed of plants such as thyme and lemon balm ought not to suggest for sowing in this regions. Manuscript profile -
Open Access Article
39 - Effect of drought stress on quantitative and qualitative traits of two forage sorghum cultivars in Jiroft region
Mehrdad Abdi Mahmoud Habibi To evaluation the effect of different drought stress levels on yield and yield components of two forge sorghum cultivars vic. Speedfeed and Pegah, an experiment was conduct in Agricultural and Natural Recourses Research Center of Jirof in 2014. Experimental design More To evaluation the effect of different drought stress levels on yield and yield components of two forge sorghum cultivars vic. Speedfeed and Pegah, an experiment was conduct in Agricultural and Natural Recourses Research Center of Jirof in 2014. Experimental design was split plot based on randomized complete block in three replications. The main plots were three irrigation levels including 33, 66 and 100% of plant water requirement and sub plots were forage sorghum cultivars. Drought stress affected significantly on all studied traits such as fresh and dry forage yield in both cultivars. Also, drought stress caused decrement in total fresh yield in forage sorghum. In intensive and moderate drought stress fresh forage yield decreased up to 47 and 17% comparing to normal irrigation, respectively. Pegah cultivar in both stressed and none-stressed conditions had higher yield than Speedfeed. Raw protein, fiber and ash percentage increased by improvement in drought stress condition. Also, these qualitative traits in Pegah were better than Speedfeed. In deficit water condition in forage sorghum cultivation, it is possible to use drought resistant cultivars and decreasing of irrigation intervals especially in sensitive plant stages and harvest higher amounts of forage yield Manuscript profile -
Open Access Article
40 - Effect of osmopriming and drought stress on seed germination of Tagetes erecta
In order to evaluate the seed germination indices of Tagetes) Tagetes erecta (under smopriming and drought stress treatments, an experiment was conducted as factorial in a randomized complete block design with three replications at the agronomy laboratory, faculty of ag MoreIn order to evaluate the seed germination indices of Tagetes) Tagetes erecta (under smopriming and drought stress treatments, an experiment was conducted as factorial in a randomized complete block design with three replications at the agronomy laboratory, faculty of agriculture, Shahrekord University. For this purpose, drought stress in levels of 0, -4, -8 and -12 bar and priming of seeds in levels of 0, -2, -4, -6 and -8 bar were applied using PEG6000. In this experiment, characteristics of germination percentage, germination rate, seed vigor index and mean germination time were evaluated. The results showed that by increasing drought stress from 0 to -4 bar, germination percentage, germination rate and seed vigor index significantly decreased while mean germination time increased and reached to 0 at the potentials of -8 and -12 bar. The maximum germination rate was observed at -2 bar priming whereas the increasing percentage was 24.91 compared to control. Also, it was found that by increasing drought stress, at the level of -4 bar, the maximum germination percentage, germination rate and seed vigor index obtained and the minimum of mean germination time was at -2 bar priming. In general, the osmopriming was able to increase the tolerance of Tagetes seeds against drought stress during germination and improve the properties of Tagetes seed germination. Manuscript profile
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