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      • Open Access Article

        1 - Comparison of the antioxidant effect of vitamin E and Curcuma Longa L. extract on the histopathological lesions of Liver and kidney following aspartame consumption in rat
        Ghavidel, S., Davari, S.A.*, Rasekh, M. .
        Aspartame is one of the most widely used artificial sweeteners in worldwide. The aim of this study was comparison of the antioxidant effect of vitamin E and Curcuma Longa L. extract on the histopathological lesions of aspartame consumption in rat. 32 males adult Wistar More
        Aspartame is one of the most widely used artificial sweeteners in worldwide. The aim of this study was comparison of the antioxidant effect of vitamin E and Curcuma Longa L. extract on the histopathological lesions of aspartame consumption in rat. 32 males adult Wistar rats were randomly divided into four equal groups as follows: (1) control, (2) receiving aspartame (350 mg/kg) orally, (3) receiving aspartame (350 mg/kg) orally and vitamin E (400 mg/kg) by peritoneal injection, (4) receiving aspartame (350 mg/kg) and Curcuma Longa L. extract (200 mg/kg) orally for 1 month. At the end of the experiment, after tissue processing of livers and kidneys of rats, histopathological changes were examined and analyzed by using the Kruskal-Wallis test. Histopathological examination of liver in group 2 showed disruption of the hepatic cords, vacuolar degeneration and accumulation of necrotic materials in hepatocytes. Furthermore, renal tissue evaluation revealed degeneration of proximal and distal convoluted tubules; glomerular atrophy and increasing of urinary space. Above-mentioned lesions were significantly improved in groups 3 and 4 in comparison to group 2 (P<0.001). Besides, Vitamin E and Curcuma Longa L. extract had higher therapeutic effects in the liver tissue in comparison to the kidney. Furthermore, treatment with vitamin E caused a significant decrease of histopathological lesions in comparison to Curcuma Longa L. extract (P<0.001). These results showed the antioxidant effects of vitamin E and Curcuma Longa L. extract on the lesions of aspartame consumption and this protection effect was more pronounced in the group received vitamin E. Manuscript profile
      • Open Access Article

        2 - The effect of turmeric (Curcuma longa) powder on liver function, serum levels of pro-inflammatory cytokines, and antioxidant status biomarkers in male Japanese quails fed a cadmium-contaminated diet
        , O Karimi , M.R Mofdi , M. Bitaraf Sani
        Environmental pollution by cadmium (Cd) is increasing. The entry of this heavy toxic metal into the food chain is a serious danger to human and animal populations. This study aims to evaluate the effect of turmeric (Curcuma longa) powder (TP) containing 2.96% of total c More
        Environmental pollution by cadmium (Cd) is increasing. The entry of this heavy toxic metal into the food chain is a serious danger to human and animal populations. This study aims to evaluate the effect of turmeric (Curcuma longa) powder (TP) containing 2.96% of total curcuminoides (TCM) in modulating the adverse impacts of Cd in Japanese quail. 180 22-day-old male Japanese quails were randomly divided into six groups for 23 days and fed a basal diet (BD) supplemented with 3 gr/kg TP (containing 88.18 mg of TCM), 5 mg/kg TP (containing 148 mg of TCM), 100 mg/kg Cd, 3 mg/kg TP plus 100 mg/kg Cd, and 5 gr/kg TP and 100 mg/kg Cd. The addition of TP to the Cd-contaminated diet reduced serum levels of pro-inflammatory cytokines TNF-αand IL-6, improved total antioxidant capacity, increased SOD and CAT activity, as well as decreasing MDA concentration. The TP supplementation significantly (p<0.05) reduced the harmful effects of Cd on body weight loss, relative liver weight gain, and total protein concentration, besides increasing serum levels of ALT, AST, and ALP enzymes. The findings of this study suggest that TP may reduce the toxic effects of Cd in Japanese quail by improving antioxidant status and reducing the activity of pro-inflammatory cytokines. The addition of 5 g/kg TP to the Cd-contaminated diet results in more antioxidant and anti-inflammatory properties than 3 g/kg TP. Manuscript profile
      • Open Access Article

        3 - مطالعه شاخص های رشد میکروسپوروم کنیس و تریکوفیتون منتاگروفیتس در چالش با عصاره های متانولی دارچین و زردچوبه
        ماکان رفاعت مهدی منصوری
      • Open Access Article

        4 - اثر عصاره زردچوبه در پیشگیری از ضایعات هیستوپاتولوژی سنگدان در مسمومیت با آفلاتوکسین در جوجه‌های گوشتی
        نادر رنگساز مجید غلامی آهنگران شهرزاد عزیزی نوشا ضیاء جهرمی
      • Open Access Article

        5 - Effects of three spices powders on mortality and progeny of adults of lesser grain borer, Rhyzopertha dominica (F.) (Col., Bostrichidae)
        Sh. Ashouri N. Shayesteh
        In this study, an experiment was conducted to investigate the toxicity of three spices powders species, cinnamon (Cinnamomum aromaticum Ness.), turmeric (Curcuma longa L.) and red pepper (Capsicum annuum L.) on adults of lesser grain borer (Rhyzopertha dominica F.). Exp More
        In this study, an experiment was conducted to investigate the toxicity of three spices powders species, cinnamon (Cinnamomum aromaticum Ness.), turmeric (Curcuma longa L.) and red pepper (Capsicum annuum L.) on adults of lesser grain borer (Rhyzopertha dominica F.). Experiments were done at five different rates 0.5, 0.85, 1.5, 3 and 5 % (wt/wt) with four replications under laboratory conditions (28±1°C, 70±5 % Rh). Twenty adult insects (1-4 day olds) were released in each treatment. The mortality was noted 1, 3, 5, 7 and 14 days after exposure. All insects were removed from all replications after 14 days and the experiments were monitored for the extra 36 days in order to count the number of adult offsprings. The results revealed that the powders had significant insecticidal effects on adults of this insect compare to the control. The toxicities of these powders increased with increase in dosage as well as increase in the period of exposure to the plant materials. Highest mortalities were recorded at the highest dosages and exposure times with turmeric, red pepper and cinnamon, respectively. LD50values (after 14 days) for turmeric, red pepper and cinnamon were 1.49, 2.10 and 3% of adult weights respectively. All tested materials at the highest dosages reduced significantly F1 progeny emergence of R. dominica. Howevercinnamon powder at 5 % (wt/wt) prevented reproduction completely (100%). This investigation showed that all three powders spices are suitable in protecting wheat grains against the lesser grain borer. Manuscript profile
      • Open Access Article

        6 - خواص، روش‌های سنتز و کاربردهای کورکومین به‌عنوان منبع طبیعی سلامت
        سعیده ابراهیمی اصل رضا جوانمردی عاطفه بدر
      • Open Access Article

        7 - Histopathological study on the effects of turmeric (Curcuma longa linn.) powdwer on renal ischemia-reperfusion injuryin rats
        داریوش Mohajeri GH Mousavi M.B Mansouri
        Renal ischemia/reperfusion (I/R) injury is a major cause of acute renal failure (ARF), which is faced in many clinical situations. This study was designed to investigate the effect of pre-treatment with turmeric (Curcuma longa linn) powder on kidney histopathology and f More
        Renal ischemia/reperfusion (I/R) injury is a major cause of acute renal failure (ARF), which is faced in many clinical situations. This study was designed to investigate the effect of pre-treatment with turmeric (Curcuma longa linn) powder on kidney histopathology and function markers in renal ischemia / reperfusion (IR) induced injury in the rats. A total of 80 male Wistar rats were randomly divided into 4 groups: sham, IR model and two I/R+TREE (2%and4%) - treated groups (n=20 per group). I/R groups’ kidneys were subjected to 60 min of global ischemia at 37oc followed by 30min of reperfusion. After 24h of reperfusion period, the rats were sacrificed. Kidney function tests and histopathological examination were also performed. Results were compared with a group of rats with sham operation. High serum creatinine, blood urea nitrogen and uric acid were observed in I/R rats compared to the sham rats. Pre-treatment of turmeric powder for 30 days prior to IR operation improved renal function reduced IR induced renal inflammatory and oxidative injury. The results of this study showed that turmeric powder significantly prevented renal I/R-induced functional and histological injuries. Manuscript profile
      • Open Access Article

        8 - اثر تنش خشکی بر رشد و میزان فعالیت آنزیم های آنتی اکسیدانی کاتالاز (Curcuma longa L.) و آسکوربات پراکسیداز در گیاه زردچوبه
        زهره زمانی اکبر مستاجران غلامرضا اصغری
      • Open Access Article

        9 - Phytochemical, antibacterial and anti-Alzheimer's evaluation of turmeric medicinal plant extract (Curcuma longa) by inhibiting the production of amyloid nanobiofibrils
        zahra Sayadi Ghasabeh amir arasteh
        Turmeric, scientifically known as Curcuma longa L., belongs to the zingiberaceae family. Due to the need to find new antimicrobial drugs, in this study the phytochemical evaluation, antibacterial and inhibitory effects of turmeric extract were investigated on the produc More
        Turmeric, scientifically known as Curcuma longa L., belongs to the zingiberaceae family. Due to the need to find new antimicrobial drugs, in this study the phytochemical evaluation, antibacterial and inhibitory effects of turmeric extract were investigated on the production of amyloid nanobiofibrils. Dry and abraded skin of the plant was prepared from India in autumn 2016 and then extracted by maceration method. Analysis of secondary compounds of the extract was performed by gas chromatography-mass spectrometry. The anti-microbial effect of aqueous and hydro-alcoholic extract of turmeric was investigated by the agar well diffusion method, MIC and MBC on two Escherichia coli and Staphylococcus aureus bacteria. Anti-Alzheimer's effects of Hydro-alcoholic extract on the production of amyloid fibrils were studied by spectrophotometry. The results showed that Turmerone and Zingiburn were the most abundant compounds in hydro-alcoholic extract with 21.26% and 11.65%, respectively. The diameter of the non-growth halo in the hydro-alcoholic extract was 12 for Escherichia coli and 13 mm for Staphylococcus aureus and in the case of aqueous extract, no growth halo was created. The MIC was reported in hydro-alcoholic extracts for Staphylococcus aureus and Escherichia coli at 26 and 53, respectively and in the aqueous extract for both bacteria at 123 mg/ml. MBC levels were also reported in the presence of hydro-alcoholic extracts for Staphylococcus aureus and Escherichia coli at 53 and 106, respectively and for aqueous extract for both bacteria at 247 mg/ml. Increasing the concentration of Hydro-alcoholic extract reduced the production of amyloid fibrils by up to 40 % of the initial amount and this decrease was confirmed by transmission electron microscopy. Hydro-alcoholic extract of turmeric with antimicrobial and reducing effects on the production of amyloid fibrils, can be used as one of the useful drugs to reduce the complications of Alzheimer's disease. Manuscript profile
      • Open Access Article

        10 - تاثیرعصارة اتانولی پودر زرد چوبه بر پایداری اکسایشی روغن سویا
        عطیه علیزاده حمید توکلی پور محسن مختاریان
      • Open Access Article

        11 - اثر اسید جیبرلیک واسید سالیسیلیک بر متابولیت های ثانویه موجود در برگ گیاه زردچوبه (Curcuma longa L)
        مریم وکیل زاده انارکی فروغ مرتضایی نژاد فریبا خلیلی محمد مهدی قیصری مهتاب اصفهانی زاده حسین پور
        مقدمه و هدف: زردچوبه با نام علمی (Curcuma longa L.)از خانواده زنجبیل(Zingiberaceae)، گیاهی چندساله، دارویی و  دارای ریزوم میباشد. این گیاه دارای خواص دارویی بسیار زیادی از جمله خاصیت ضد­سرطان، ضد­باکتری و ضد­هپاتیت است. در این تحقیق اثر غوطه­وری ریز More
        مقدمه و هدف: زردچوبه با نام علمی (Curcuma longa L.)از خانواده زنجبیل(Zingiberaceae)، گیاهی چندساله، دارویی و  دارای ریزوم میباشد. این گیاه دارای خواص دارویی بسیار زیادی از جمله خاصیت ضد­سرطان، ضد­باکتری و ضد­هپاتیت است. در این تحقیق اثر غوطه­وری ریزوم­های زردچوبه در اسید­جیبرلیک و اسید­سالیسیلیک بر متابولیت های ثانویه موجود در برگ این گیاه مورد بررسی قرار گرفت. روش تحقیق: به منظور بررسی اثر اسید­جیبرلیک و اسید­سالیسیلیک بر برگ گیاه زردچوبه، ریزوم­های تایلندی این گیاه که به مدت دو سال در شرایط گلخانه دانشگاه آزاد اسلامی واحد خوراسگان (اصفهان) رشد داده شده بودند قبل از کشت در غلظت ppm ­150اسید جیبرلیک به مدت چهار ساعت و غلظت ppm ­400اسید سالیسیلیک به مدت یک ساعت غوطه­ور گردید. آزمایش در شرایط گلخانه­ای بصورت فاکتوریل در قالب بلوک­­های کامل تصادفی با سه تکرار اجرا گردید. بعد از کامل شدن طول دوره رشد، برگ تیمارها توسط دستگاه سوکسله با حلال پترولیوم اتر عصاره گیری شد و در نهایت شناسایی ترکیبات موجود در برگ این گیاه با استفاده از دستگاه GC/MS صورت گرفت. نتایج و بحث: بیشترین متابولیت­های موجود در برگ شامل کامفور، پینن، بتا-اسیمن و 8 -1سینئول می باشد. کاربرد اسید جیبرلیک منجر به افزایش کامفور، 8 -1سینئول، کامفن،α-پینن و همچنین ترکیبات ترپنی جدید مانند ویتامینE ، α-توژن و لیمونن در برگ این گیاه گردید. کاربرد اسید سالیسیلیک منجر به افزایش متابولیت هایی همچون کامفور، 8 -1سینئول، کامفن در برگ این گیاه گردید. توصیه کاربردی/ صنعتی: در تولید متابولیک، با توجه به خواص دارویی گیاه زردچوبه، متابولیت­های ثانویه­ای که خواص دارویی گوناگون دارند می تواند توسط تنظیم کننده­های رشد افزایش یابد. از آنجایی که زردچوبه به دلیل داشتن متابولیت های بسیار مهم یکی از گیاهان دارویی بسیار مهم در طب سنتی و مدرن می باشد، کاربرد اسید­جیبرلیک و اسید­سالیسیلیک باعث افزایش متابولیت های ثانویه در این گیاه گردیده است که می تواند نوع هر متابولیت براساس نتایج این تحقیق افزایش یابد. Manuscript profile
      • Open Access Article

        12 - اثرات سطوح مختلف اسانس‌های زردچوبه و رزماری بر عملکرد و ثبات اکسیداتیو گوشت جوجه‌های گوشتی
        م. قره‌جانلو م. مهری ف. شیرمحمد
        آزمایش حاضر به منظور بررسی اثرات استفاده از سطوح مختلف اسانس‌های زردچوبه و رزماری بر عملکرد و ثبات اکسیداتیو گوشت جوجه‌های گوشتی انجام گرفت. آزمایش با استفاده از 540 قطعه جوجه‌ گوشتی (کاپ 500) در نه تیمار و چهار تکرار در قالب طرح کاملاً تصادفی به روش فاکتوریل سه در سه، More
        آزمایش حاضر به منظور بررسی اثرات استفاده از سطوح مختلف اسانس‌های زردچوبه و رزماری بر عملکرد و ثبات اکسیداتیو گوشت جوجه‌های گوشتی انجام گرفت. آزمایش با استفاده از 540 قطعه جوجه‌ گوشتی (کاپ 500) در نه تیمار و چهار تکرار در قالب طرح کاملاً تصادفی به روش فاکتوریل سه در سه، متشکل از سه سطح اسانس زردچوبه (0=T1، 75=T2 و 150=T3 میلی‌گرم اسانس بر کیلوگرم جیره) و سه سطح اسانس رزماری (0=R1، 100=R2 و 200=R3 میلی‌گرم اسانس بر کیلوگرم جیره) اجرا شد. نتایج نشان داد که تیمار R2T3 و R3T3 در مقایسه با گروه شاهد، در سه هفته اول پرورش سبب افزایش وزن بدن شد (05/0>P). در طول دوره رشد (42-21 روزگی) و نیز در کل دوره، گروه شاهد در مقایسه با سایر تیمارها به استثناء تیمارهای R1T2، R2T3 و R3T1 پایین‌ترین ضریب تبدیل خوراک را داشت (05/0>P). بالاترین وزن نسبی لاشه و ماهیچه ران به ترتیب در جوجه­هایی مشاهده شد که مقدار 75 و 150 میلی­گرم اسانس زردچوبه دریافت کرده بودند (05/0>P). افزودن اسانس زردچوبه به جیره سبب کاهش معنی­دار وزن نسبی پانکراس، پیش­معده، سنگدان و چینه­دان شد (05/0>P). بالاترین وزن نسبی جگر در جوجه­های گروه شاهد مشاهده شد (05/0>P). اندازه­گیری میزان مالون­دی­آلدئید (MDA) گوشت طی 30 روز نگهداری در دمای 20- درجه سانتی‌گراد نشان داد که همه­ تیمارها، به استثناء تیمارهای R3T2 و R3T3، در مقایسه با گروه شاهد کاهش معنی­داری در MDA نشان دادند (05/0>P). شصت روز پس از نگهداری گوشت در دمای 20- درجه سانتی‌گراد، کمترین میزان MDA در جوجه­های تیمارهای R1T2، R2T2، R3T3 و R3T1 مشاهده شد (05/0>P). نتایج نشان داد که استفاده همزمان از اسانس زردچوبه و رزماری در جیره، بهبودی در عملکرد جوجه‌های گوشتی ایجاد نکرد در حالیکه این افزودنی­ها پتانسیل بالایی در بهبود ثبات اکسیداتیو گوشت و کاهش میزان MDA در طی نگهداری 30 و 60 روزه گوشت در دمای 20- درجه سانتی‌گراد داشت. Manuscript profile
      • Open Access Article

        13 - آنالیز مقایسه‌ای بین اثرات افزودن خوراک با پودر سیر (Allium sativum) و ریشه زردچوبه (Curcuma longa) روی عملکرد مرغان تخمگذار و کیفیت تخم مرغ
        م. حاج آید آ. آیسا م. نومی
        این آزمایش، در طول یک دوره 7 هفته‌ای برای بررسی اثرات استفاده از سطوح متفاوتی از پودر سیر و ریشه زردچوبه، روی عملکرد مرغان تخمگذار، ویژگی‌های کیفی تخم مرغ و محتوای کلسترول در زرده انجام شد. 216 مرغ تخمگذار سفید نروژی 27 هفته‌ای به‌طور تصادفی به 9 تیمار با 8 تکرار از هرک More
        این آزمایش، در طول یک دوره 7 هفته‌ای برای بررسی اثرات استفاده از سطوح متفاوتی از پودر سیر و ریشه زردچوبه، روی عملکرد مرغان تخمگذار، ویژگی‌های کیفی تخم مرغ و محتوای کلسترول در زرده انجام شد. 216 مرغ تخمگذار سفید نروژی 27 هفته‌ای به‌طور تصادفی به 9 تیمار با 8 تکرار از هرکدام 3 پرنده اختصاص یافت. آنها با جیره‌های غذایی صفر، 0.5، 1، 1.5 و 2 درصد از پودر سیر یا ریشه زردچوبه تغذیه شدند. داده‌های عملکرد تخمگذاری، کیفیت تخم ‌مرغ، و محتوای کلی کلسترول در زرده تخم ‌مرغ در تخم ‌مرغ‌ها اندازه‌گیری شد. وزن زنده نهایی بدن، خوراک مصرفی روزانه و نسبت تبدیل خوراک توسط جیره‌های مکمل‌سازی شده با پودر سیر و ریشه زردچوبه تحت تأثیر قرار نگرفتند (P≥0.273). هیچ تفاوت معنی‌داری در تولید تخم ‌مرغ، نرخ تخم‌ مرغ‌های بدون پوسته و وزن تخم‌ مرغ شناسایی نشد (P≥0.375). با این حال، اضافه کردن 2 درصد پودر سیر نرخ تخم ‌مرغ‌های شکسته را کاهش داد (P=0.030). مکمل‌سازی پودر سیر و ریشه زردچوبه اثر معنی‌داری روی نرخ تخم ‌مرغ‌های دو زرده داشت (P<0.0001). وزن سفیده، قطر و ارتفاع همچنین توسط پودر سیر و ریشه زردچوبه اضافه شده تحت تأثیر قرار گرفتند (P≤0.007). وزن پوسته تخم ‌مرغ در گروه مرغان 1 درصد ریشه زردچوبه (5.64 گرم) سنگین‌تر از گروه‌های شاهد و سیر 5 درصد بود. افزودن خوراکی 1 درصد پودر سیر و ریشه زردچوبه غلظت کلسترول زرده تخم ‌مرغ را کاهش داد (P=0.024). در نتیجه، اضافه کردن خوراکی پودر سیر و ریشه زردچوبه می‌تواند به عنوان جایگزینی برای بهبود کیفیت تخم‌ مرغ در مرغان تخمگذار استفاده شود. Manuscript profile
      • Open Access Article

        14 - The Study of Oxidative Stress-Dependent Changes Caused by Social Stress in Brain and Kidney Tissues
        Irandokht Zeynaei Shahrbanoo Oryan Mohammadreza Vaezmahdavi Akram Eidi Mehrdad Roghani
        The effect of social stress on the occurrence of cardiovascular and mental diseases is obvious. In order to investigate the effect of these stresses on oxidative stress induction, and changes in the oxidant and antioxidant levels, the model for roommate change restricti More
        The effect of social stress on the occurrence of cardiovascular and mental diseases is obvious. In order to investigate the effect of these stresses on oxidative stress induction, and changes in the oxidant and antioxidant levels, the model for roommate change restriction and observation in the presence of curcuma longa antioxidant was designed A total of 60 Wister rats were kept under standard conditions of temperature, light, and water. In the under-stress groups, each rat was provided with one third of its common food. The roommate change stress and observation were applied to two groups of these rats. Two groups of rates were fed by the food contained curcuma longa. These rats kept under defined conditions for each group for 4 months i.e., roommate change, observation, curcuma longa; food restriction, observation, roommate change, curcuma longa; control; control, curcuma longa. After the rats' maintenance period was completed, they were anesthetized with ether and their kidney and brain tissues were homogenized. Each of the given factors i.e., malon-dialdehyde, glutathione, nitric oxide, cathepsin D and lipofuscin was measured in tissues. The malon-dialdehyde level increased significantly both in brain and kidney in under-stress group. The level of nitric oxide and glutathione increased in brain, but the activity of cathepsin D and lipofuscin accumulation remained unchanged. Also the amount of nitric oxide and glutathione remained the same. The brain is more sensitive to MDA formation, but the amount of glutathione and nitric oxide is higher. Thus social stress induced changes do not occur equally in kidney and brain tissues. Manuscript profile
      • Open Access Article

        15 - Investigating the Different Antioxidant Effect of Turmeric and Melatonin in Three Tissues of Brain, Liver and Kidney under the Conditions of Social Stress
        Irandokht Zeynaei Shahrbanoo Oryan Mohammadreza Vaez Mahdavi Akram Eidi
        The purpose of this research is to investigate the antioxidant effect of turmeric and melatonin in three tissues of brain, liver and kidney under the same stressful conditions.For this purpose, 40 male Wistar rats were kept in different conditions to induce the desired More
        The purpose of this research is to investigate the antioxidant effect of turmeric and melatonin in three tissues of brain, liver and kidney under the same stressful conditions.For this purpose, 40 male Wistar rats were kept in different conditions to induce the desired stresses.Stresses include: food restriction, change of roommate and observation in conditions of having and not having turmeric and melatonin antioxidants.The rats were kept for 10 weeks in the defined conditions for each group, and after the completion of the period, the level of glutathione present in the homogenate of the brain, liver and kidney tissues was evaluated.At first, to ensure the induction of stress, the amount of glutathione and malondialdehyde was measured and compared to the control group.The result indicated the increase of glutathione and malondialdehyde and in fact the induction of stress.The general result indicates the effectiveness and protective effect of turmeric and melatonin in inhibiting oxidative stress in all three mentioned tissues, but this effectiveness is not seen in all three tissues with the same intensity.Contrary to the fact that turmeric was able to reduce the level of malondialdehyde and prove its antioxidant role in all three tissues of the brain, liver and kidney, it could not show its antioxidant role well in the liver tissue and the amount of glutathione did not decrease.Unlike turmeric, melatonin was able to show its antioxidant role in liver tissue cells better than in brain and kidney tissue, so that it was able to reduce the level of glutathione in these two tissues.Therefore, antioxidants probably have different functions in different tissues. . Manuscript profile
      • Open Access Article

        16 - Comparing the Effect of Turmeric and Vitamin E in the Improvement of Lipid Profile and Biochemical Markers of Liver and Kidney in Japanese Quails
        Majid Gholami-Ahangaran
        The present study aimed to investigate effect of turmeric on the biochemical markers of liver and kidney in Japanese quail. For this purpose, 180 one-day Japanese quails were divided randomly into four groups with three repetitions.  They were grown since one day t More
        The present study aimed to investigate effect of turmeric on the biochemical markers of liver and kidney in Japanese quail. For this purpose, 180 one-day Japanese quails were divided randomly into four groups with three repetitions.  They were grown since one day to 42 days under similar conditions. All groups applied the basic standard diet based on the NRC recommendation. Group 1 received basic diet with 0.5 % turmeric. Group 2 received basic diet with 1% turmeric. Group 3 received basic diet with 0.25 % vitamin E. Group 4 as the control group used basic diet. All quails were slaughtered at the age of 42 days and serum samples were collected for evaluating the cholesterol, HDL, LDL, triglyceride, total protein, uric acid and liver enzyme (ALT and AST) levels. The result of the previous study indicated that using turmeric at the level of 0.5 and 1% at the diet of quail is equal to all markers of Triglyceride metabolism, cholesterol and protein as well as the markers related to the evaluation of liver and kidney function by adding vitamin E. In general, a relative improvement was observed in the mentioned markers than the control group. Data comparison showed that using turmeric at the level of 1% had better effects than adding 0.5 % turmeric in most cases. It seems that using turmeric in the diet of quail can improve the markers related to fat metabolism. Manuscript profile