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Open Access Article
1 - Comparison of the antioxidant effect of vitamin E and Curcuma Longa L. extract on the histopathological lesions of Liver and kidney following aspartame consumption in rat
Ghavidel, S., Davari, S.A.*, Rasekh, M. .Aspartame is one of the most widely used artificial sweeteners in worldwide. The aim of this study was comparison of the antioxidant effect of vitamin E and Curcuma Longa L. extract on the histopathological lesions of aspartame consumption in rat. 32 males adult Wistar MoreAspartame is one of the most widely used artificial sweeteners in worldwide. The aim of this study was comparison of the antioxidant effect of vitamin E and Curcuma Longa L. extract on the histopathological lesions of aspartame consumption in rat. 32 males adult Wistar rats were randomly divided into four equal groups as follows: (1) control, (2) receiving aspartame (350 mg/kg) orally, (3) receiving aspartame (350 mg/kg) orally and vitamin E (400 mg/kg) by peritoneal injection, (4) receiving aspartame (350 mg/kg) and Curcuma Longa L. extract (200 mg/kg) orally for 1 month. At the end of the experiment, after tissue processing of livers and kidneys of rats, histopathological changes were examined and analyzed by using the Kruskal-Wallis test. Histopathological examination of liver in group 2 showed disruption of the hepatic cords, vacuolar degeneration and accumulation of necrotic materials in hepatocytes. Furthermore, renal tissue evaluation revealed degeneration of proximal and distal convoluted tubules; glomerular atrophy and increasing of urinary space. Above-mentioned lesions were significantly improved in groups 3 and 4 in comparison to group 2 (P<0.001). Besides, Vitamin E and Curcuma Longa L. extract had higher therapeutic effects in the liver tissue in comparison to the kidney. Furthermore, treatment with vitamin E caused a significant decrease of histopathological lesions in comparison to Curcuma Longa L. extract (P<0.001). These results showed the antioxidant effects of vitamin E and Curcuma Longa L. extract on the lesions of aspartame consumption and this protection effect was more pronounced in the group received vitamin E. Manuscript profile -
Open Access Article
2 - Low Fat Cream Cheese Fortification Based on β-Cyclodextrin / Inulin Nano Emulsions with Vitamins E and D
M. Tahery T. MostaghimIntroduction: Food fortification is a way to compensate for the lack of micronutrients in society, which is used by all countries in the world to minimize or control the lack of essential nutrients. Meanwhile, the cream cheese is a suitable carrier for fortification due MoreIntroduction: Food fortification is a way to compensate for the lack of micronutrients in society, which is used by all countries in the world to minimize or control the lack of essential nutrients. Meanwhile, the cream cheese is a suitable carrier for fortification due to its wide range of uses. The aim of this study was to fortify the low-fat cream cheese based on β-cyclodextrin / inulin nano emulsions with vitamins D and E. Materials and Methods: Nano emulsions were prepared with 400, 450 and 500 units of vitamin E and 5, 10 and 15 micrograms per gram of vitamin D. Free radical scavenging tests (antioxidant activity), trapping rate, release rate and nano emulsions size were evaluated. The cream cheese tests consisted of the assessments regarding percent acidity, fat, moisture contents, textural properties (hardness, adhesion and elasticity) and peroxide index. Sensory characteristics (taste, texture, appearance, aroma and overall acceptance) were assessed by a 5-point Hedonic method. Results: The results showed that by increasing the use of these two vitamins, the morphological properties of nano emulsions changed and their size increased. Trapping rates ranged from 65 to 98% and release rates ranged from 61 to 84%. The results showed that during the storage period of the cheese in the time intervals of production days, fifteenth, thirtieth, forty-fifth and sixtieth day storage, the index of hardness, adhesion, acidity and peroxide number increased significantly (p≥0.05). Moisture content, elasticity index and sensory characteristics decreased significantly (p≥0.05). The fat content of treated cheese did not show significant differences with the control sample (p <0.05). Conclusion: Considering all physicochemical properties as well as the results of sensory evaluation, the treatment with 450 units of vitamin E and 5 micrograms per gram of vitamin D was selected as the optimal treatment. Manuscript profile -
Open Access Article
3 - Effect of Postnatal Administration of Vitamin E on Autistic-like Behavior in a Rat Model of Autism
Azin Sadat Seyed Atashi Hamid SepehriBackground & aim: autism spectrum disorders (ASD) represent a heterogeneous group of neurodevelopmental syndromes that are clinically characterized by deficits in social interactionand repetitive behaviors . The pathogenesis of ASD is complex and not fully disclosed MoreBackground & aim: autism spectrum disorders (ASD) represent a heterogeneous group of neurodevelopmental syndromes that are clinically characterized by deficits in social interactionand repetitive behaviors . The pathogenesis of ASD is complex and not fully disclosed. Vitamin E is a fat-soluble vitamin that has strong antioxidant activity. Previous studies have reported decreased plasma levels of vitamin E in autism spectrum patients and beneift effect of prenatal treatment . The present study was conducted to investigate the effect of two week postnatal treatment of vitamin E on autism-like behavior in rats exposed to VPA. Materials and methods: pregnant rats were divided into two groups from the 14th day of pregnancy, one group received only normal food and water, and the other group was injected with valproic sodium on the 14th day of pregnancy. The offspring were tested for repetitive behaviors and cognitive ability with a T-maze task and social interaction with a play behavior task on 44st of Postnatal daysResults: Administration of vitamin E in mice treated with VPA increased cognitive flexibility compared to VPA treatment alone. Vitamin E treatment of mice treated with VPA led to the improved social behavior of pinning with strange mice . Administration of vitamin E in VPA-treated mice did not improve any of the social behaviors including sniffing, running, and grooming compared to valproic acid treatment aloneConclusion: The findings of the present study showed that vitamin E treatment improves cognitive flexibility and to some extent social behaviors in autistic rats. Manuscript profile -
Open Access Article
4 - Effects Dietary Vitamin E and B2 on Hematological and Immunological Parameters Of Juvenile Barbel SturgeonAcipenser nudiventris
Alireza Ashouri Hossein Kara Mohammad Ali Yazdani Sadati Rezvanollah KazemiInroduction and Objective: Vitamins are organic compounds which are essential for normal growth and metabolic activities in fish and shrimp. This study was conducted to evaluate the effects of dietary vitamins E and B2 on growth performance of Acipenser nudiventris fing MoreInroduction and Objective: Vitamins are organic compounds which are essential for normal growth and metabolic activities in fish and shrimp. This study was conducted to evaluate the effects of dietary vitamins E and B2 on growth performance of Acipenser nudiventris fingerlings.Materials and Methods: The feeding trial was conducted by a completely randomized design with six treatments. Acipenser nudiventris fingerlings with the initial mean weight of 301.5 g (meanSD) were fed five experimental diets for 8 weeks; diet one supplemented with vitamin E (300 mg/kg), diet 2 supplemented with riboflavin (B2) (20mg/kg), diet 3 supplemented with vitamin E (300 mg/kg) and riboflavin (B2) (15 mg/kg), diet 4 supplemented with vitamin E (300 mg/kg) and riboflavin (B2) (20 mg/kg) and diet 5 supplemented with vitamin E (300 mg/kg) and riboflavin (B2) (25 mg/kg). A control group was also used that was fed a diet lacking vitamin E and B2. Blood parameters including RBC, WBC, hemoglobin and hematocrit and Immune system indicator (Lysosyme, IgM and Compliment) were determined.Results: The result showed. Increasing of vitamin E and Riboflavin were influenced on blood and immune system fish. Fish fed 300 mg/ kg dietary had highest erythrocyte, lysosyme activity, IgM, total immunoglobulin. Amount of hemoglobin and compliment activity in fish fed with 20 mg/kg riboflavin showed significant difference with control group (P Manuscript profile -
Open Access Article
5 - Effect of vitamin E supplementation on delayed onset muscle soreness in young men
Mostafa Kashef -
Open Access Article
6 - The effect of a course of forced swimming exercises with vitamin E on the histopathology of uterine tissue in endometriosis model rats
Shahrbano jaafari Hajar Abbaszadeh parvin farzanegi Leila zameniPurpose: The purpose of this study was to investigate the effect of a course of swimming exercises with vitamin E on the histopathology of uterine tissue in endometriosis model rats. Method: This study was of an experimental type, in which the number of 5 8-week-old fem MorePurpose: The purpose of this study was to investigate the effect of a course of swimming exercises with vitamin E on the histopathology of uterine tissue in endometriosis model rats. Method: This study was of an experimental type, in which the number of 5 8-week-old female Wistar rats after the induction of the model was randomly divided into 5 healthy control groups, endometriosis, endometriosis+ vitamin E, endometriosis+swimming, endometriosis+swimming+Vitamin E were divided. The amount of vitamin consumption was 200 mg/kg per body weight of each rat, and the swimming training program was for 8 weeks, five days a week, and every day for 30 minutes. After anesthesia, an autopsy was performed and uterine tissue samples were taken. Histological results obtained from uterine tissue samples were expressed descriptively with pictures. Findings: The results showed that in the rats of the endometriosis model, the cylindrical epithelium had completely disappeared and was only visible in some areas compared to the control group. On the other hand, in the vitamin and exercise groups, although the size of the cyst was reduced, the structure of the epithelium was not completely normal. However, blood sampling of the tissue was done well and vessels were visible around the tissue. On the other hand, it was observed that the light-colored areas indicated the induction of tissue death in the layers around the cyst, and these symptoms could be considered as a reason for the shrinking of the cyst size and its removal in the future. Conclusion: It seems that performing swimming exercises and taking vitamin E at the same time can help reduce tissue damage and improve the histopathological factors of uterine tissue in endometriosis model rats. Manuscript profile -
Open Access Article
7 - The effect of diets supplemented with vitamins C and E on WBC fluctuations of Acipenser ruthenus
mahmoud bahmaniAbstract[1]This study was conducted to determine the different levels of dietary vitamin C and vitamin E on WBC fluctuations of sterlet (Acipenser ruthenus) in Dr. Dadman International Sturgeon Research Institute. Nine diets supplemented with a combination of 0, 100 and MoreAbstract[1]This study was conducted to determine the different levels of dietary vitamin C and vitamin E on WBC fluctuations of sterlet (Acipenser ruthenus) in Dr. Dadman International Sturgeon Research Institute. Nine diets supplemented with a combination of 0, 100 and 400 mg/kg vitamin C, L-ascorbyl-2-polyphosphate (APP), and 0, 100 and 400 mg/kg vitamin E, D-alpha- tocopherol, were fed to sterlet in 2 replicates for 15 weeks. Fifteen fish with the average weight of 350.92±14.28 were distributed to each of 18 tanks after adaptation with experimental diet. The fish were fed 3% of body weight per day. Blood samples were obtained from three fish of each tank at the end of the experiment. The results of blood samples at the end of 15th week revealed a significant difference between WBC and monocytes, lymphocytes and neutrophils (P<0.05).The highest and the lowest WBC count was observed in fish fed with diets containing 100 mg kg1- vitamin E and 400 mg kg1- vitamin C (diet 6) and fish fed with 400 mg kg1- vitamin E and 400 mg kg1- vitamin C (diet 9), respectively. Also, the highest monocytes, lymphocytes and neutrophils were observed in fish fed with diets containing 0 mg kg1- vitamin E and 0 mg kg1- vitamin C (diet 1), 0 mg kg1- vitamin E and 100 mg kg1- vitamin C (diet 2) and 400 mg kg1- vitamin E and 400 mg kg1- vitamin C (diet 9), respectively. On the other hand, the lowest monocytes, lymphocytes and neutrophils were observed in fish fed with diets containing 100 mg kg1- vitamin E and 0 mg kg1- vitamin C (diet 4), 400 mg kg1- vitamin E and 400 mg kg1- vitamin C (diet 9) and 0 mg kg1- vitamin E and 100 mg kg1- vitamin C (diet 2), respectively. Manuscript profile -
Open Access Article
8 - Effect of vitamin E in prevention of lipopolysaccharide induced fetal injuries in the rat
hosein mohammadzadeh masoud delashoub mansoor khakpoorLipopolysaccharides (LPS) are one of the most important factors in the formation of embryonic damages. These damages include intra-uterine growth retardation, intra-uterine fetal death, embryonic absorption and preterm birth and are associated with oxidative stress caus MoreLipopolysaccharides (LPS) are one of the most important factors in the formation of embryonic damages. These damages include intra-uterine growth retardation, intra-uterine fetal death, embryonic absorption and preterm birth and are associated with oxidative stress caused by lipopolysaccharides. This study aimed to investigate the protective effect of vitamin E on lipopolysaccharide induced fetal damages in the rat. In this study, 48 pregnant rats were selected and allocated to 4 groups. In groups 1 and 2, 75 µgr/kg of lipopolysaccharides were injected intraperitoneally on day 15 to 17 of pregnancy. A week before administration of lipopolysaccharides to rats of groups 2 and 3, they received 20 mg/kg of intramuscular vitamin E daily. Group 4 received normal saline intraperitoneally as a control group. In day 18 of pregnancy all mice were euthanized. In each animal, the number of live and dead embryos were counted. Then the live fetuses were weighed and the length of crown–rump, metacarpus, metatarsus, anterior phalanges, posterior phalanges and sternum were determined. In addition, the amounts of malondialdehyde and glutathione were measured in maternal and embryonic liver and placenta. Administration of lipopolysaccharides significantly increased fetal mortality and reduced fetal weight, length of the tail and crown–rump, live embryos and skeletal ossification of the metacarpus, metatarsus, anterior and posterior phalanges and sternum. Results showed that simultaneous administration of vitamin E and lipopolysaccharides reduced damages and improved respective injuries in mice embryos. Manuscript profile -
Open Access Article
9 - Comparison of Serum Levels of Vitamin C, Vitamin E, Selenium and the Activity of Glutathione Peroxidase Enzyme in Horses Affected with Strangles and Healthy Horses
Mohammadreza Valilou Sina Moghaddam Ali HassanpourStrangles is a prevalent infectious and contagious disease among Equidae that is caused by Streptococcus equi subspecies equi. The present study was performed on patient and healthy horses to evaluate serum levels of vitamin C (vitamin C), vitamin E (vitamin E), seleniu MoreStrangles is a prevalent infectious and contagious disease among Equidae that is caused by Streptococcus equi subspecies equi. The present study was performed on patient and healthy horses to evaluate serum levels of vitamin C (vitamin C), vitamin E (vitamin E), selenium (Sel) and glutathione peroxidase (GPx). Clinical signs and bacterial culture confirmed sixty patient horses. To separate the serum, blood samples were taken from the jugular vein of the studied horses. Blood samples were also taken from 52 healthy horses with similar conditions (age, diet, etc.). Serum levels of Vit E, Vit C, Se and serum’s activity of GPx were measured in samples taken from healthy and patient horses. The mean serum concentration of vitamin E, selenium and serum glutathione peroxidase activity in patient horses were significantly reduced. A significant increase in the patient's hemoglobin concentration was observed. The study of the relationship between serum selenium and antioxidants (serum glutathione peroxidase activity, vitamin E and hemoglobin) showed that increasing serum selenium also increased the antioxidants studied. Serum antioxidant markers were significant in patient horses in all three cases. The final outcome is that in horses which infected to strangles antioxidants like selenium, glutathione peroxidase and vitamin E reduced and these antioxidant intakes for dealing with them this issue should be considered in treating these patients. Manuscript profile -
Open Access Article
10 - The effect of vitamin E and selenium on serum injection on serumic levels of T3 and T4 hormones in the Arabian horse
بهرام Amouoghli-Tabrizi A. Hassanpour M. Khakpour Y. Mohamadpour-Tanha This study was conducted evaluate the effect of vitamin E and Selenium injection on serumic levels of thyroid hormones in the Arabian horse. Twelve Arabian stallions of approximately equal age were selected and based on their age (4 and 5 years old), More This study was conducted evaluate the effect of vitamin E and Selenium injection on serumic levels of thyroid hormones in the Arabian horse. Twelve Arabian stallions of approximately equal age were selected and based on their age (4 and 5 years old), allocated to tow groups each consisting of six animals. In each group, three of the six horses were injected by vitamins E and selenium at a dose rate of 1cc/30 kg intramuscularly every tow days and the other three animals which were chosen as the controls were similarly injected by normal saline solution. Two days alter each injection; blood samples of the horses in each group were collected using venoject from the jugular vein. After separating the blood serum by centrifuging, the levels of T3 and T4 were measured using the ELISA technique. Following the first injection, the serumic levels of thyroid hormones demonstrated a significant increase in comparison with the controls (p<0.05) while after the second injection, the serumic levels of T3 and T4 had decreased to normal values similar to the control groups. However, following the third injection the decreased in T3 and T4 levels was clearly evident and statistically significant (p<0.05). According to the results of the present study, the injection of vitamin E and selenium for more than twice leads to decrease in the seumic levels of T3 and T4 hormones of the horse and this is coupled with reduction of the basic body metabolism which is not beneficial for the animal. Manuscript profile -
Open Access Article
11 - Effect of supplementing ascorbic acid, vitamin E and betaine on the performance, immune response and blood parameters in broiler
S.M MotamediIn order to investigate the effects of vitamins C and E and betaine on performance, immune response and blood parameters of broiler chickens, an experiment was conducted with completely randomized block design consisting of 6 treatments and 5 replicates with 30 chicks i MoreIn order to investigate the effects of vitamins C and E and betaine on performance, immune response and blood parameters of broiler chickens, an experiment was conducted with completely randomized block design consisting of 6 treatments and 5 replicates with 30 chicks in each replicate. The groups were assigned to receive the treatment diets as follows: diet with no feed additive (control); diet supplemented with vitamin C; diet supplemented with vitamin E; diet supplemented with betaine; diet supplemented with vitamin E and betaine; diet supplemented with vitamin E, vitamin C and betaine. Body weight, feed intake, body weight gain, feed conversion ratio and mortality were determined over the course of the experiment. At 35 days of age, two birds per replicate were randomly selected and 2 ml blood sample was collected to measure plasma concentration of T3 and T4 hormones. IgM and IgG antibody response to SRBC were also determined at 28 days of age. Body weight, FI and FCR were not affected by different treatments over the course of the study. Broilers fed diet supplemented with vitamin C, vitamin E and betaine showed the highest survival percentage and production index as compared with the other treatments. But it was not significantly different with the control group. IgM and IgG antibody response to SRBC, hematocrit percentage and plasma concentration of T3 and T4 also were not affected by different dietary treatments. The results of this experiment showed that there were no significant differences among the treatments in the performance, immune response and blood parameters of broiler chicken. Manuscript profile -
Open Access Article
12 - Effect of different levels of selenium and vitamin E on blood biochemical parameters in the Japanese quail
hossein zadeh adamnejad jamshid ghiasi ghalekandi yahya ebrahimnejad Co-administration of vitamin E and selenium has positive effects on growth performance of avian species, but their effect is not fully elicited in the Japanese quail. Also, controversial reports exist for the effect of vitamin E and selenium on avian perfor More Co-administration of vitamin E and selenium has positive effects on growth performance of avian species, but their effect is not fully elicited in the Japanese quail. Also, controversial reports exist for the effect of vitamin E and selenium on avian performance. This study was designed to investigate the effect of different levels of selenium (0, 0.2 and 0.4 mg/kg) and vitamin E (0, 150 and 300 mg/kg) in the diet of the Japanese quail. Birds received mesh diet from the start of the study, then selenium and vitamin E were added on day 17. At the end of the study, after food deprivation for 6 hours, Japanese quail (1 male and 1 female) were selected and blood samples collected for biochemical investigations and determination of glucose, albumin, total protein, cholesterol, triglyceride, HDL and LDL levels. There was significant decrease in cholesterol, glucose, and triglyceride levels and significant decrease in albumin and total protein levels on day 35 (p<0.05). Effect of vitamin E and selenium was not significant on serum LDL level but, administration of vitamin E significantly increased serum HDL levels (p<0.05). These results suggest that co-administration of selenium and vitamin E could have positive effects on blood biochemical parameters in the Japanese quail. Manuscript profile -
Open Access Article
13 - Effect of vitamin E supplementation on serumic levels of lipids and lipoproteins in cholesterol-fed male rat
M.H Khayat Nouri محمد Mashayekhi رضا Jafari M.R Nasirzade جعفر Rahmani Hypercholesterolemia is one of the risk factors of cardiovascular diseases. High blood cholesterol affects the general health and increases the mortality rate of cardiovascular diseases. High levels of cholesterol in the diet increases LDL levels and More Hypercholesterolemia is one of the risk factors of cardiovascular diseases. High blood cholesterol affects the general health and increases the mortality rate of cardiovascular diseases. High levels of cholesterol in the diet increases LDL levels and decreases the activity of LDL receptors in the liver. Oxidation of vascular LDL lipoproteins increases the development of atherosclerosis. Previous studies have indicated that consumption of antioxidants decreases hypercholesterolemia. This study evaluates the effect of vitamin E supplementation on blood lipid levels in high cholesterol-fed rats. In this experimental study, three groups of male rats (n=10 for each group) were used. The control group received basic diet and one of the other two groups received a diet containing one percent cholesterol and while the other received the same diet plus vitamin E supplement (2500 IU/kg in dry matter of the diet) for one month. After determining the values of TC, LDL, VLDL, HDL and TG the results indicated that in rats fed with 1% cholesterol apart from HDL and VLDL the other lipids had increased significantly compared with the control group (p<0.01). Supplementation with vitamin E significantly decreased the TC and LDL levels in comparison with the 1% cholesterol fed group (p<0.01). This effect of vitamin E may be related to its antioxidant and inhibitory effects on lipoprotein synthesis pathway. The validity of these points in humans needs further investigations. Manuscript profile -
Open Access Article
14 - Effects of cysteamine and vitamin E addition to semen extender on post-thawed microscopic sperm parameters of buffalo bulls
rahim beheshti jamshid ghiyasi This study was designed to investigate the effect of cysteamine and vitamin E on post thaw buffalo bull's sperm quality. For this purpose, 20 ejaculates from four buffalo bulls possessing more than 70% visual sperm motility were diluted at 37◦C in BioXcell& More This study was designed to investigate the effect of cysteamine and vitamin E on post thaw buffalo bull's sperm quality. For this purpose, 20 ejaculates from four buffalo bulls possessing more than 70% visual sperm motility were diluted at 37◦C in BioXcell® extender. The diluted semen was cooled to 4◦C within 2 hours, equilibrated at 4◦C following the addition of (0.75, 1.5, 2 and 5 mM) of vitamin E and (7.5, 12.5, 15 and 20 mM) cysteamine per 90 ml, filled in 0.5 ml French straws and were subjected to cooling condition before being plunged into liquid nitrogen. Semen was thawed at 37◦C for 40 seconds after 72 hours of storage inside liquid nitrogen .Post-thaw sperm motility and some qualitative parameters of each frozen semen sample were assessed by using computer assisted semen analyzer (CASA). In general, the results showed that the addition of 1.5 mM vitamin E and 20 mM cysteamine in the commercial diluents BioXcell extender for freezing buffalo semen increased the motility of spermatozoa and some qualitative parameters to post-thawed buffalo sperm. Manuscript profile -
Open Access Article
15 - Histopathological evaluation of the effect of vitamin E on rat kidney after complete unilateral urethral obstruction
G.h Mousavi داریوش Mohajeri علی Agebati Maleki رامین Kafash Elahi مهرداد Neshat میرهادی Khayat NouriVitamin E is an important antioxidant, which plays a vital role in preventing free radical induced reperfusion injuries. Any disorder in the normal urinary flow is termed obstructive nephropathy which could ultimately lead to hydronephrosis, atrophy and complete impairm MoreVitamin E is an important antioxidant, which plays a vital role in preventing free radical induced reperfusion injuries. Any disorder in the normal urinary flow is termed obstructive nephropathy which could ultimately lead to hydronephrosis, atrophy and complete impairment of renal function. The aim of this study was to determine the effect of vitamin E on renal tissue following complete unilateral urethral obstruction in the rat. In this experimental study, 30 adult male Sprague-Dawley rats were randomly divided into three groups each containing 10 rats. The first group was considered as the control group. Following Unilateral urethral obstruction (UUO), rats in the second group received olive oil intraperitoneally for 15 days starting one day before surgery. Group three rats were given 50 Iu/kg of Vitamin E intraperitoneally for 15 days starting one day before unilateral obstruction (UUO-Vit E). Rats were euthanized at day 14 after surgery for histopathological evaluation and their left kidneys were collected and fixed in formalin and stained with Hematoxylen and Eosin, Trichrome-masson and Periodic Acid Schiff techniques. Histopathological evaluation revealed dilation of the Bowman’s capsule, severe glomerular and tubular atrophy, periglomerular sclerosis, interstitial infiltration of mononuclear cells, severe diffuse tubular degeneration, epithelial thickening of Bowman’s capsule, perivascular edema, interstitial fibrosis, hemorrhage and sub capsular fibrosis in the UUO group. Vitamin E administration in the UUO-Vit E group significantly decreased renal tissue lesions and fibrosis. The result of the present study indicated that urethral obstruction leads to severe renal fibrosis and tissue damage and concurrent administration of Vitamin E decreases tissue lesions and fibrosis resulting from the obstruction. Manuscript profile -
Open Access Article
16 - The relationship between vitamin A, E, and some trace minerals and poor growth in replacement heifers
علی Sadeghi-nasab بهرام Dadmehr S.M Zolhavarieh علی Hassanpour A.A BahariOne of the most important principles of cattle breeding is rearing and feeding of replacement calves. In this clinical survey three groups, consisting of 12-13 months old heifers, inseminated heifers up to 45 days of gestation and 4-5 months pregnant heifers suffering f MoreOne of the most important principles of cattle breeding is rearing and feeding of replacement calves. In this clinical survey three groups, consisting of 12-13 months old heifers, inseminated heifers up to 45 days of gestation and 4-5 months pregnant heifers suffering from nutritional problems which exhibited clinical signs of decreased growth rate, general debility, poor coat growth and discoloration and infertility were selected for pooled blood sampling and analysis of vitamin A, E and selenium, copper, zinc and manganese values. There was clear deficiency of vitamin E and manganese while selenium deficiency was slight correlating with clinical signs. It is suspected that improper and mouldy feeds presented to these non-lactating groups resulted in primary and secondary deficiencies of mentioned elements and finally have led to poor growth rate and fertility insufficiency in affected animals. Manuscript profile -
Open Access Article
17 - The effect of vitamin E- selenium injection on serumic levels of Albumin, Protein, Calcium, Phosphorous, Alkaline phosphates, Alaninamonitransferas and Aspartataminotransferas in the Arabian horse
بهرام Amouoghli Tabrizi منصور KhakpoorThis study was performed to evaluate the effect of vitamin E and Selenium injection on serumic levels of albumin, protein, calcium, phosphorous, alkaline phosphates, alaninamonitransferas and aspartataminotransferas in the Arabian stallions. In this study 12 Arabian hor MoreThis study was performed to evaluate the effect of vitamin E and Selenium injection on serumic levels of albumin, protein, calcium, phosphorous, alkaline phosphates, alaninamonitransferas and aspartataminotransferas in the Arabian stallions. In this study 12 Arabian horses were selected in 2 groups of 4 and 5 years old. In each group, horses were allocated to two sub groups of controls and treatment, each of them containing three animals. In the treatment group, 1cc/30 kg vitamin E and selenium was injected intramuscularly in 2 day intervals for 6 days, while in the control group the same amounts of normal saline (0.9%) was injected. Blood samples of all animals were collected from the jugular vein at days 2, 4 and 6 and their sera were harvested by centrifuging and the levels of the parameters were measured using commercial kits and the spectrophotometric method. The results of this study indicated that there was no significant difference on mean serumic albumin, phosphorous, alkaline phosphates, alaninamonitransferas, and spartataminotransferas in the studied animals while mean serumic protein values of 4 year old horses indicated a significant difference following the third vit E – Selenium injection (p<0.05). The levels of calcium showed a significant difference following the second injection in 4 and 5 years old horses (p<0.05). Based on the results, it can be concluded that vit E – Selenium injection could be beneficial for horses without having any side effects on the liver and kidney but alterations of other biochemical and hematologic parameters should also be investigated. Manuscript profile -
Open Access Article
18 - The Effect of Vitamin E Supplementation on Atherogenic and Lipid Peroxidation Responses Induced by Interval Training in Obese Male Wistar Rats
Fatemeh Hosseini reza rezaeeshirazi Saeed Ghorbani Abuzar JorbonianIntroduction: Obesity causes high disorders as increasing atherogenic index and physical activity is able to control obesity that can possibly increase lipid peroxidation. Therefore, the study was performed to evaluate the effect of vitamin E supplementation on atheroge MoreIntroduction: Obesity causes high disorders as increasing atherogenic index and physical activity is able to control obesity that can possibly increase lipid peroxidation. Therefore, the study was performed to evaluate the effect of vitamin E supplementation on atherogenic and lipid peroxidation responses induced by interval training in obese male Wistar rats.Materials and methods: The present study was a laboratory experimental method. Thirty male Wistar rats were randomly selected and divided into four groups: training (TG; N=8), supplementation (SG; N=8), training with supplementation (TSG; N=8), and Control (CG; N=8). The interval training consisted of 30 minutes running on treadmill per day, 5 days a week, for 8 weeks. Vitamin E supplementation was also available daily with 300 mg/g of body weight along with drinking water in SG. Finding: The finding revealed a significant decrease between TSG compared with CG in MDA (p=0.010), AIP (p=0.001), TC (p=0.001), TG (p=0.001) and LDL-C (p=0.001) variables. Also, MDA variable a significant decrease between TSG compared with TG (p=0.001). A significant decrease between TG compared with CG and SG in AIP (p=0.031), TC (p=0.024), TG (p=0.012) and LDL-C (p=0.010) variables were observed; while HDL-C variable showed a significant increase between TSG compared with CG (p=0.024) and TG compared with CG (p=0.031) (p≤0.05).Discussion and Conclusion: Vitamin E supplementation can improve atherogenic index and by increasing of antioxidant system causes reduce exercise-induced lipid peroxidation in obese rats; while the positive effects of improving body composition and controlling obesity were achieved to exercise. Manuscript profile -
Open Access Article
19 - بررسی اثر حفاظتی اسپیرولینا، عصاره چای سبز و ویتامین E در مقابل استرس اکسیداتیو ناشی از کادمیوم بر روی مغز رت
امیر علی شهبازفر سید جمال امامی رضا اسدپورمقدمه و هدف: امروزه جلبک اسپیرولینا و چای سبز به عنوان یکی از مواد با فواید تغذیه ای فراوان شناخته شده اند. در تحقیق حاضر اثرات حفاظتی این دو ماده در جلوگیری از آسیب اکسیداتیو ناشی از کادمیوم بر روی مغز موش سوری مورد بررسی قرار گرفت و نتایج با اثرات حفاظتی ویتامین Moreمقدمه و هدف: امروزه جلبک اسپیرولینا و چای سبز به عنوان یکی از مواد با فواید تغذیه ای فراوان شناخته شده اند. در تحقیق حاضر اثرات حفاظتی این دو ماده در جلوگیری از آسیب اکسیداتیو ناشی از کادمیوم بر روی مغز موش سوری مورد بررسی قرار گرفت و نتایج با اثرات حفاظتی ویتامین E به عنوان یک انتی اکسیدان های قوی و شناخته شده مقایسه شد. روش تحقیق:روش تحقیق: بدین منظور تعداد‎‎‏30‏‎‎سر‎‎رت‎‎ماده‎‎بالغ‎‎ ‎به طور‎‎مساوی‎‎و‎‎تصادفی‎‎به‎‎پنج‎‎گروه‎‎تقسیم‎‎شدندو به مدت چهار هفته تحت رژیم درمانی قرار گرفتند. کنترل ، کادمیوم (مخلوط با جیره)، کادمیوم و محلول اسپیرولینا (محلول در آب)، کادمیوم وعصاره چای سبز ( محلول در آب)، کادمیوم و ویتامین E ( تزریق داخل صفاقی). در انتهای تحقیق موش ها به روش انسانی کشته شدند و مغز ها جهت تثبیت سازی در فرمالین انداخته شد. هیپوکامپ، caudate putamen، corpus callosum، قشر مخ و مخچه با میکروسکوپ نوری جهت مشاهده و بررسی ضایعات مورد مطالعه قرار گرفتند. نتایج و بحث: تغییرات پاتولوژیکی از قبیل نوروفاژی ، پرخونی، خون ریزی، نکروزو آتروفی نورون ها، کروماتولیز مزکزی، نکروز لایه ای و اسفنجی شدن در نواحی مختلف مغز مشاهده شد. هنگام استفاده از کادمیوم به تنهایی قطر لایه مولکولار و گرانولر مخچه و همچنین اندازه سلول های پورکنژ به طور قابل توجهی کاهش یافت. هنگام استفاده از اسپیرولینا همراه با کادمیوم تغییری در سلول های پورکنژ مشاهده نشد و تغییرات لایه های مخچه بسیار ناچیز بود (P<0.05). هم چنین ، اسپیرولینا شمار سلول های نکروز شده در هیپوکمپ و قشر مخ را به شدت کاهش داد. اسپیرولینا در مقایسه با عصاره چای سبز و ویتامین E اثر حفاظتی قوی تری در مقابل کادمیوم از خود نشان داد. عصاره چای سبز کمترین اثر را داشت. هیپوکمپ بیش از سایر نواحی مورد بررسی دچار ضایعات شده بود. توصیه کاربردی/ صنعتی: نتایج نشان می دهند که اسپیرولینا یک منبع خوب از آنتی اکسیدان با خواصی حتی بهتر از ویتامین E می باشد و می تواند به تنهایی یا همراه با دیگر آنتی اکسیدان ها جهت جلوگیری از آثار مخرب ترکیبات اکسیداتیو مورد استفاده قرار گیرد. Manuscript profile -
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20 - اثر گیاه چویل بر فعالیت آنتی اکسیدانی سرم و برخی واکنش های ایمنی در جوجه های گوشتی
رضا گواهی غلامرضا قلمکاری مجید طغیانی شهین اقبال سعید محمد محمدرضایی مهدی شهریاری علیرضا دهقانی ابری -
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21 - مقایسه منابع مختلف سلنیوم و ویتامین E در جیره مرغهای تخمگذار و اثرات آنها بر سلنیوم و کلسترول تخم مرغ، کیفیت و ثبات اکسیداتیو
ف. اسدی ف. شریعتمداری م.ا. کریمی ترشیزی م. محیطی اصلی م. قناعت پرست رشتیآزمایشی برای مقایسه اثرات مکمل سازی جیره مرغ­های تخمگذار با منابع غیرآلی و آلی مختلف سلنیوم بر کیفیت و ثبات اکسیداتیو تخم مرغ در مدت نگهداری انجام شد. تعداد 81 قطعه مرغ تخمگذار لهمن LSL سفید در سن 35 هفتگی در قفس در یک طرح کاملاً تصادفی با 9 گروه تیماری، 3 تکرار و 3 Moreآزمایشی برای مقایسه اثرات مکمل سازی جیره مرغ­های تخمگذار با منابع غیرآلی و آلی مختلف سلنیوم بر کیفیت و ثبات اکسیداتیو تخم مرغ در مدت نگهداری انجام شد. تعداد 81 قطعه مرغ تخمگذار لهمن LSL سفید در سن 35 هفتگی در قفس در یک طرح کاملاً تصادفی با 9 گروه تیماری، 3 تکرار و 3 قطعه پرنده در هر تکرار تقسیم شدند. مرغ­های هر گروه با جیره مربوطه که شامل جیره پایه با سلنیت سدیم، مخمر غنی از سلنیوم، سیتوپلکس-سلنیوم و سلنومکس در دو سطح مختلف از 3/0 و 6/0 میلی­گرم در کیلوگرم، یا 200 میلیگرم در کیلوگرم ویتامین E تغذیه شدند. به منظور جلوگیری از چالش قضاوت نام تجاری، حروف A، B و C برای منابع آلی مختلف سلنیوم استفاده شد. پس از 56 روز تغذیه جیره­های آزمایشی، تخم مرغ­های تولیدی مرغ­ها برای آزمایش جمع­آوری شدند. افت وزن تخم مرغ در مدت ذخیره­سازی در دمای 4 درجه در گروه تغذیه شده با 3/0 میلی­گرم از منبع B سلنیوم در کیلوگرم خوراک کمتر بود (05/0>P). گروه­های تغذیه شده با ویتامین E و سلنیوم میزان مالون­دی­آلدئید کمتری از آنهایی که جیره مکمل نشده مصرف نمودند، داشتند (01/0>P). منبع C سلنیوم آلی در مقایسه با دیگر منابع سلنیوم یا گروه شاهد مالون­دی­آلدئید کمتری داشت. مکمل نمودن سلنیوم در جیره غلظت سلنیوم زرده را افزایش داد (01/0>P) و اثر منبع C سلنیوم بیشتر بود. مکمل­سازی سلنیوم و ویتامین E سبب کاهش محتوای کلسترول سرم و زرده شد (01/0>P). نتایج نشان می­دهد که اثربخشی منبع C سلنیوم آلی برای افزایش ذخیره سلنیوم در تخم مرغ و بهبود کیفیت تخم مرغ در مقایسه با سایر منابع سلنیوم بیشتر است. Manuscript profile -
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22 - اثر افزودن ویتامین ای و کروم به جیره غذایی بر عملکرد، ویژگیهای کیفی تخم مرغ و برخی از فراسنجههای خونی مرغهای تخمگذار در شرایط دمایی معمولی و تنش گرمایی
م. ترکی م. کرمی ح. محمدیآزمایش حاضر به منظور بررسی اثر افزودن ویتامین ای و کروم به جیره غذایی بر عملکرد، ویژگیهای کیفی تخم مرغ، غلظت کروم و انسولین سرم خون و همچنین فعالیت آنزیم گلوتاتیون پراکسیداز در مرغهای تخمگذار در شرایط دمایی عادی و تنش گرمایی انجام شد. به صورت آزمایش فاکتوریل 2 × Moreآزمایش حاضر به منظور بررسی اثر افزودن ویتامین ای و کروم به جیره غذایی بر عملکرد، ویژگیهای کیفی تخم مرغ، غلظت کروم و انسولین سرم خون و همچنین فعالیت آنزیم گلوتاتیون پراکسیداز در مرغهای تخمگذار در شرایط دمایی عادی و تنش گرمایی انجام شد. به صورت آزمایش فاکتوریل 2 × 2، چهار جیره غذایی همسان به لحاظ انرژی و پروتئین شامل دو سطح مکمل ویتامین ای (0 و 200 میلی­گرم بر کیلو­گرم) و دو سطح مکمل کروم (0 و 1200 میلی­گرم بر کیلو­گرم) تهیه و با 6 تکرار و 6 پرنده در هر تکرار درطی دوره آزمایش 15 هفتهای در اختیار مرغهای تخمگذار لوهمن قرار داده شد (144n=). در طول 10 هفته نخستین (سن 40-30 هفتگی)، پرندهها در دمای معمولی (استاندارد C° 17) و بعد از آن تا آخر دوره آزمایش در دمای بالا (تنش گرمایی C° 32) قرار داشتند. افزودن کروم به جیره، میزان مصرف خوراک را در طول تنش گرمایی کاهش داد. افزودن ویتامین ای و کروم به جیره غذایی بر وزن تخم مرغ، توده تخم مرغ، وزن سفیده، وزن مخصوص تخم مرغ، شاخص شکل تخم مرغ، رنگ زرده و شاخص زرده تأثیر معنیداری نداشت. افزودن ترکیبی ویتامین ای و کروم به جیره غذایی واحد هاو را قبل و بعد از تنش گرمایی و همچنین تولید تخم مرغ، وزن زرده و پوسته تخم مرغ را در طی تنش گرمایی افزایش داد. جیرههای غذایی اثری بر غلظت سرمی کروم و فعالیت آنزیم گلوتاتیون پراکسیداز در سن 45 هفتگی (پایان استرس گرمایی و پایان آزمایش) نداشتند. افزودن ویتامین ای و کروم به جیره غذایی، غلظت سرمی انسولین را افزایش داد. افزودن ترکیبی ویتامین ای و کروم به جیره غذایی مرغهای تخمگذار میتواند تا حدی اثر منفی تنش گرمایی بر عملکرد و ویژگیهای کیفی تخم مرغ را کاهش دهد. Manuscript profile -
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23 - اثر جلبک گونه سارگاسوم و ویتامین E بر ماندگاری گوشت غنی شده با روغن ماهی در جوجههای گوشتی
ف. آرمین ش. رحیمی ع. مهدی آبکنار ی. غفرانی ایواری ح. ابراهیمیاین مطالعه به منظور بررسی اثر جلبک قهوه­ای دریایی و ویتامین E بر ماندگاری گوشت مرغ غنی شده با روغن ماهی انجام شد. در این آزمایش 360 قطعه جوجه گوشتی یکروزه (آربوراکرز پلاس) که به صورت تصادفی در 6 تیمار با 4 تکرار شامل 15 جوجه اختصاص داده شدند. گروههای آزمایشی شامل: Moreاین مطالعه به منظور بررسی اثر جلبک قهوه­ای دریایی و ویتامین E بر ماندگاری گوشت مرغ غنی شده با روغن ماهی انجام شد. در این آزمایش 360 قطعه جوجه گوشتی یکروزه (آربوراکرز پلاس) که به صورت تصادفی در 6 تیمار با 4 تکرار شامل 15 جوجه اختصاص داده شدند. گروههای آزمایشی شامل: گروه مصرف کننده جیره پایه (ذرت و سویا)، جیره پایه به همراه روغن ماهی، جیره پایه به همراه ویتامین E، جیره پایه به همراه روغن ماهی و ویتامین E، جیره پایه به همراه روغن ماهی و 5 درصد جلبک دریایی خشک شده و جیره پایه به همراه روغن ماهی و 10 درصد جلبک دریایی خشک شده بودند. روغن ماهی و ویتامینE در 2 هفته آخر پرورش استفاده شد. جوجهها در روز 42 کشتار شده و نمونههای گوشت تهیه شده در دمای 4 درجه سانتی گراد نگهداری شدند. میزان مالون­دیآلدهید موجود در نمونهها در روزهای 0، 3 و 6 بعد از کشتار اندازهگیری شد. نتایج نشان داد که روغن ماهی باعث افزایش پراکسیداسیون گوشت شده و گذشت زمان باعث افزایش شدت آن میشود. تیمارهای دریافت کننده ویتامین E پایینترین میزان مالون­دیآلدهید را نشان داند و همچنین باعث افزایش ماندگاری گوشت­های غنی شده با روغن ماهی شدند. مصرف 10 درصد جلبک دریایی ماندگاری گوشت نواحی سینه و ران را در روزهای 3 و 6 بعد از کشتار افزایش داد. بررسی پروفیل اسیدهای چرب نشان داد که استفاده از روغن ماهی باعث انباشت معنی دار اسید چرب امگا 3 در عضلههای ران و سینه میشود. همچنین مصرف همزمان روغن ماهی با جلبک دریایی باعث افزایش انباشت امگا 3 در عضله ران شد. ازطرفی مصرف جلبک دریایی سبب کاهش معنی دار میزان کلسترول و تری­گلیسیرید سرم خون جوجه­ها شد. به صورت کلی مصرف ویتامین E و جلبک قهوهای دریایی باعث افزایش ماندگاری گوشتهای غنی شده با امگا 3 شد. Manuscript profile -
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24 - عملکرد تولیدی مرغهای تخمگذار تغذیه شده با سطوح مختلف دانههای خشک تقطیر شده با حلال با یا بدون افزودنیهای خوراک
ک.م. ماهروس م. عبدل-هاک آ. آتیا م. ال-هینداویهدف از این کار بررسی افزودن دانه­های خشک تقطیر شده با حلال (DDGS) به عنوان جایگزینی برای کنجاله سویا در جیره مرغ­های تخمگذار قهوه­ای هایسکس با یا بدون آنزیم و یا افزودن ویتامینE بر عملکرد تولید بود. تعداد 180 قطعه مرغ تخمگذار قهوه­ای هایسکس در سن 2 Moreهدف از این کار بررسی افزودن دانه­های خشک تقطیر شده با حلال (DDGS) به عنوان جایگزینی برای کنجاله سویا در جیره مرغ­های تخمگذار قهوه­ای هایسکس با یا بدون آنزیم و یا افزودن ویتامینE بر عملکرد تولید بود. تعداد 180 قطعه مرغ تخمگذار قهوه­ای هایسکس در سن 26 هفتگی به طور تصادفی به 15 گروه تیماری در یک آزمایش 3 × 5 فاکتوریل تقسیم شدند، شامل پنج سطح جایگزینی DDGS با کنجاله سویا (0، 25، 50، 75 و 100 درصد) و سه سطح افزودنی خوراکی (بدون، آنزیم 250 میلی­گرم­/­کیلوگرم جیره غذایی و یا 200 میلی­گرم ویتامین E­/­کیلوگرم جیره غذایی) از سن 38-26 هفتگی بود. نتایج نشان داد که افزایش سطح جایگزینی DDGS بیش از 50 درصد، میانگین مصرف خوراک و ضریب تبدیل خوراک، تعداد و وزن توده تخم مرغ را کاهش داد (01/0>P). همه این صفات نتایج رضایت بخشی را در مرغ­های تغذیه شده با 25 یا 50 درصد DDGS جایگزینی با کنجاله سویا داشت. افزودن آنزیم یا ویتامین E به طور معنی­داری (01/0>P) مصرف خوراک و وزن توده تخم را کاهش داد. می­توان نتیجه گرفت که DDGS با موفقیت جایگزین کنجاله سویا در جیره مرغ تخمگذار تا 50 درصد بدون اثرات منفی بر روی عملکرد مرغ­های تخمگذار شد. Manuscript profile -
Open Access Article
25 - سلول سوختی میکروبی: روش جدید برای تعیین ارزش غذایی پنبه دانه کامل مورد استفاده در تغذیه نشخوارکنندگان
م. بشارتی ا. تقی زادههدف از این مطالعه، تعیین همبستگی بین تکنیک تولید گاز آزمایشگاهی و سلول­های سوختی میکروبی و معرفی روش جدید برای ارزیابی خوراک مورد استفاده در جیره­های نشخوارکنندگان است. تیمارهای مورد آزمایش: 1) جیره کنترل (بدون پنبه دانه، مننسین و ویتامین E، (CD)؛ 2) جیره حاوی 2 Moreهدف از این مطالعه، تعیین همبستگی بین تکنیک تولید گاز آزمایشگاهی و سلول­های سوختی میکروبی و معرفی روش جدید برای ارزیابی خوراک مورد استفاده در جیره­های نشخوارکنندگان است. تیمارهای مورد آزمایش: 1) جیره کنترل (بدون پنبه دانه، مننسین و ویتامین E، (CD)؛ 2) جیره حاوی 20 درصد پنبه دانه کامل (CSD)؛ 3) تیمار حاوی 20 درصد پنبه دانه کامل به همراه 12000 واحد ویتامین E به ازای هر گاو در روز (CSDE) و 4) تیمار حاوی 20 درصد دانه پنبه کامل به همراه 24 ppm مننسین در کیلوگرم DMI برای هر گاو در روز (CSDM). برای آزمایش سلول­های سوختی میکروبی، پیکربندی خانگی MFC شامل دو سیلندر از نوعPlexiglass بود. نتایج بدست آمده نشان داد که تیمار حاوی ویتامین E تولید گاز بیشتری نسبت به سایر تیمارها داشت. تولید گاز در تیمار حاوی موننسین کمتر از سایر تیمارها بود. تیمار با ویتامین E دارای مقادیر ولتاژ، جریان و قدرت بیشتری در مقایسه با سایر تیمارها بود. داده­های به دست آمده نشان داد که اضافه کردن موننسین در مقایسه با تیمار CSD باعث بهبود عملکرد سلول­های میکروبی گردید. نتایج نشان داد که بین مقادیر تولید گاز و عملکرد سلول­های سوختی میکروبی همبستگی بالایی وجود دارد. Manuscript profile -
Open Access Article
26 - تاثیر افزودن مکمل سلنیوم آلی و معدنی همراه با ویتامین E در دوره فلاشینگ بر عملکرد تولیدمثلی میشهای قزل
ح. دقیقکیا س. ساعدی ع. حسینخانیمواد معدنی و ویتامین­ها نقش مهمی در تغذیه حیوانات ایفاء کرده و اثرات مفیدی بر عملکرد تولیدمثلی حیوانات دارند. به منظور بررسی اثر مکمل سلنیوم و ویتامین E بر هورمون­ها، متابولیت­های خونی و عملکرد تولیدمثلی، 44 میش قزل 3-2 ساله با میانگین وزنی 2 ± 55 کیل Moreمواد معدنی و ویتامین­ها نقش مهمی در تغذیه حیوانات ایفاء کرده و اثرات مفیدی بر عملکرد تولیدمثلی حیوانات دارند. به منظور بررسی اثر مکمل سلنیوم و ویتامین E بر هورمون­ها، متابولیت­های خونی و عملکرد تولیدمثلی، 44 میش قزل 3-2 ساله با میانگین وزنی 2 ± 55 کیلوگرم به طور تصادفی در 4 گروه تیماری (11=n) مورد استفاده قرار گرفتند. تیمارها مشتمل بر؛ گروه A: شاهد؛ گروه B: جیره فلاشینگ با دانه جو (73 درصد)؛ گروه C: جیره فلاشینگ + ویتامین E (48 میلی­گرم در روز) + سلنیوم آلی (سلنوپروتئین، 35/1 میلی­گرم در روز) و گروه D: جیره فلاشینگ + ویتامین E (48 میلی­گرم در روز) + سلنیوم معدنی (سلنیت سدیم، 35/1 میلی­گرم در روز). چرخه­های فحلی میش­ها با استفاده از سیدر (CIDR) به مدت 14 روز، همزمان گردیدند. نتایج نشان دادند که بالاترین میزان برهزایی (4/136 درصد) و تعداد بره متولد شده (15=n) متعلق به گروه تیماری C بود. اندازه­گیری سطوح هورمونی استروژن، پروژسترون و انسولین بیانگر ارتباط این هورمون­ها با عملکرد تولیدمثلی میش­ها بود بطوریکه بالاترین میزان استروژن و انسولین (در فحلی) و پروژسترون (3 هفته بعد از جفتگیری) متعلق به گروه­های تیماری C و D بود (05/0˂P). سطوح گلوکز و کلسترول در گروه­های تیماری C و D روز قبل از سیدر برداری، فحلی و 3 هفته بعد از جفت­گیری به طور معنی­داری افزایش یافت (05/0˂P). در تمام دوره های آزمایشی، سطوح پروتئین تام و نیتروژن اوره­ای خون (BUN) در گروه­های تیماری B، C و D نسبت به گروه شاهد افزایش معنی­داری داشت (05/0˂P). استفاده از سلنیوم آلی و یا معدنی در جیره فلاشینگ اثرات مشابهی در متابولیتهای خونی و هورمون­های مرتبط با عملکرد تولیدمثلی داشت. Manuscript profile -
Open Access Article
27 - تأثیر مصرف خوراکی کولین محافظت شده و ویتامین E بر تولید شیر، ترکیبات شیر، ماده خشک مصرفی، امتیاز وضعیت بدنی و وزن بدن در گاوهای اوایل دوره شیردهی
M. Rahmani M. Dehghan-Banadaky R. Kamalyanبه منظور بررسی اثرات مصرف کولین محافظت شده یا ویتامین E بر تولید شیر، ترکیبات شیر، ماده خشک مصرفی، امتیاز وضعیت بدنی و وزن بدن در گاوهای اوایل دوره شیردهی، تعداد 24 رأس گاو هلشتاین یک شکمزا و چند شکمزا که در هفته پنجم شیردهی قرار داشتند، به مدت چهار هفته مورد آزمایش ق Moreبه منظور بررسی اثرات مصرف کولین محافظت شده یا ویتامین E بر تولید شیر، ترکیبات شیر، ماده خشک مصرفی، امتیاز وضعیت بدنی و وزن بدن در گاوهای اوایل دوره شیردهی، تعداد 24 رأس گاو هلشتاین یک شکمزا و چند شکمزا که در هفته پنجم شیردهی قرار داشتند، به مدت چهار هفته مورد آزمایش قرار گرفتند. گاوها به طور تصادفی به یکی از گروههای زیر اختصاص یافتند: I- بدون دریافت مکمل (شاهد) II- دریافت کننده کولین محافظت شده (90 گرم در روز) و III- دریافت کننده ویتامین E (4400 واحد بین المللی در روز). در این مطالعه، مصرف کولین یا ویتامین E بر ماده خشک مصرفی، وزن بدن، امتیاز وضعیت بدنی، تولید شیر، درصد و محصول اجزای تشکیل دهنده شیر به غیر از درصد مواد جامد بدون چربی در گروه کولین، تأثیری نداشت (05/0P>). مصرف کولین محافظت شده سبب افزایش درصد مواد جامد بدون چربی شیر در مقایسه با گروه شاهد و گروه ویتامین E گردید (05/0>P). نتایج این آزمایش نشان داد که مصرف کولین یا ویتامین E در جیره گاوهای اوایل دوره شیردهی تأثیری بر تولید شیر، ترکیبات شیر، ماده خشک مصرفی، وضعیت شرایط بدنی و وزن بدن نداشت. Manuscript profile -
Open Access Article
28 - Vitamin E Supplementation in Feed Containing Lemuru Fish Oil to Improve IPB-D2 Chickens Performance and Eggs Rich in Vitamin E as a Potential Functional Food
R. Nadia S. Sumiati T. Suryati -
Open Access Article
29 - The Impact of Different Levels of Vitamin E and Selenium on the Performance, Quality and the Hatchability of Eggs from Breeding Japanese Quails
م. عباسزاده مبارکی م. اقدم شهریار -
Open Access Article
30 - Impact of Storage Duration on Kernel Quality of Offspring of ‘Mamaei’ and ‘Marcona’ Almond Hybrids
Mahrokh Zahedi Mousa Rasouli Ali Imani Orang Khademi Sepideh Kalateh Jari -
Open Access Article
31 - The Possible Protective Role of Vitamin E on the Induced Silver Nanoparticles Toxicity on Filiform and Circumvallate Tongue Papillae of Albino Rats Histological and Immunohistochemical Study
Nada Tarek Zaki Mahmoud Mohamed Al Ankily Reham Magdy Amin Ahmed Mahmoud Halawa -
Open Access Article
32 - Alcoholic Extract of Vitex (Vitexagnus-castus) and vitamin E on Serum Level of Hepatic Enzymes, Glucose, Lipid Profile and Insulin in Adult Female Rats
Z. Nejaty S.E. HosseiniChronic hyperglycemias led to diabetes that was a metabolic disorder caused by a defect in insulin secretion or function with decreased serum levels of vitamin E and the liver damaged.Vitex plant traditionally wasused to treat many diseases. The present study aimed to i MoreChronic hyperglycemias led to diabetes that was a metabolic disorder caused by a defect in insulin secretion or function with decreased serum levels of vitamin E and the liver damaged.Vitex plant traditionally wasused to treat many diseases. The present study aimed to investigate the effect of Vitex and vitamin-E on serum levels on some hepatic enzyam, glucose, and insulin , lipid profile and weight was performed in rats.Methods: In this study, 40 adult female rats weighing 220 to 250 g in the controls group, and the 3 experimental groups were studied.Each group consisted of 8 mice. The experimental groups 1 weredivided by received 40mg / kg extract of Vitex, empirical 2received 40 mg/kg extract of Vitexand 40mg / kgvitamin E, and empirical 3 received 40 mg/kg vitamin E.Prescription was administered for 14 days, at the end of the fourteenth day, phlebotomizing by inter-ventricular to mice were performed and then by diagnostic kits, serum levels, insulin hormone, glucose, enzymes ALP, ALT and AST was measured. The data by using ANOVA and Tukeytest was analyzed and evaluated. The results showed that ethanol extracts of Vitex and vitamin E have no effect on glucose levels, while significantly caused to decrease the cholesterol, triglycerides, LDL, ALP and AST enzymes, and then increased insulin and HDL.Conclusion:Vitex Extract and Vitamin E due to antioxidant properties led to increased insulin hormone and HDL levels and reduced cholesterol, triglycerides, LDL ALP, AST enzymes. Manuscript profile -
Open Access Article
33 - The Effect of Diets Supplemented with Vitamins C and E on Plasma Cholesterol in Adult Sterlet, Acipenser ruthenus
مصطفی تاتینا محمود بهمنی مهدی سلطانی مهتاب قریب خانیThis study was conducted in order to characterize the different levels of dietary vitamin Cand vitamin E on plasma cholesterol of sterlet in propagation center of Sturgeon Research Institute. Nine experimental diet including threelevels of vitamin E, D-alpha-tocopherol, MoreThis study was conducted in order to characterize the different levels of dietary vitamin Cand vitamin E on plasma cholesterol of sterlet in propagation center of Sturgeon Research Institute. Nine experimental diet including threelevels of vitamin E, D-alpha-tocopherol, (0, 100 and 400 mg kg1- diet) andthreelevels of vitamin C, L-ascorbyl-2-polyphosphate, (0, 100 and 400 mg kg1- diet) wereprepared and used for feeding fish in two replicates for 15 weeks. After fish adaptations with artificial food, 15 sterlets (Acipenser ruthenus) with the average weight of 350.92andplusmn;14.28g were divided into 18 tanks. The fish were fed 2% their wet body weighs. Blood samples were obtained from three fish of each tank at the end of week 5 and week 15. The results of blood analysis showed that the highest amount of cholesterol at the end of week 5 was observed in E0 C100 mg/kg and E100 C400 mg/kg treatments (diets 2 and 6) and at the end of week 15 was observed in E100 C0 mg/kg treatment (diet 4) (Pandlt;0.05). On the other hand the lowest amount of cholesterol at the end of week 5 and week 15 was observed in E100 C100 mg/kg (diet 5) and E400 C100 mg/kg (diet 8), respectively (Pandlt;0.05). The results of this study revealed that different levels of vitamin C and vitamin E may have some effects on cholesterol fluctuations of sterlet Manuscript profile -
Open Access Article
34 - Comparative Effect of Timolol and Methanolic Extract of Zataria multiflora with Vitamin E on APO E Gene Expression and Behavioral and Biochemical Changes in Alzheimer's Rats
Samira Homayoun Pour Maryam Bananej Maryam Khosravi Hengameh AlibeikAlzheimer's Disease is the most common form of dementia, characterized by memory and cognitive deficits. Vitamin E, as an antioxidant, plays an important role in reviving free radicals and converting them into safe substances by giving hydrogen. Shirazi thyme (Zataria m MoreAlzheimer's Disease is the most common form of dementia, characterized by memory and cognitive deficits. Vitamin E, as an antioxidant, plays an important role in reviving free radicals and converting them into safe substances by giving hydrogen. Shirazi thyme (Zataria multiflora) has antibacterial, antifungal and antioxidant properties. The aim of this study is the comparative effect of timolol with methanol extract of Zataria multiflora with vitamin E on Alzheimer's disease in male Wistar rats. 40 male Wistar rats weighing approximately 200 grams were randomly divided into 5 groups of eight. Beta-amyloid 42 was used to induce Alzheimer's disease. Then, methanolic and timolol extracts were extracted from Zataria multiflora. The level of Apo E gene expression was evaluated by Real Time PCR and TC, LDL and HD biochemical factors. The expression of Apo E gene in the experimental groups increased significantly compared to the Alzheimer's group. The expression of this gene was decreased in the sham group compared to the control group. The group of Alzheimer's mice had a significant increase in total cholesterol (TC) and low-density lipoprotein (LDL) serum levels, and the level of HDL showed a significant decrease compared to the control group. Timolol, m ethanolic extract of Zataria multiflora and vitamin E have positive effects on the expression of APOA E gene in leukocytes. On the other hand, with a significant effect on HDL, the methanolic extract of Zataria multiflora can be used as an effective product to prevent and reduce the complications of Alzheimer's disease. Manuscript profile -
Open Access Article
35 - Effect of different levels of dietary vitamin E, sesamin and thymoquinone supplementation on cellular immune challenges, intestinal microbial population, intestinal morphology and MUC2 gene expression in laying Japanese quails
Yaser Rahimian Farshid Kheiri Mostafa FaghaniIn order to investigate the effect of consuming diets supplemented with different levels of vitamin E, sesamin and thymoquinone on cellular immune system challenges, intestinal morphology, intestinal microbial population and MUC2 gene expression in laying Japanese quail MoreIn order to investigate the effect of consuming diets supplemented with different levels of vitamin E, sesamin and thymoquinone on cellular immune system challenges, intestinal morphology, intestinal microbial population and MUC2 gene expression in laying Japanese quails, 210 female Japanese quails aged 85-35 days with 7 experimental treatments including the control group and those consuming vitamin E, thymoquinone and sesamin at levels of 100 and 200 ml.gram/kg of standard feed was used with 5 repetitions and 6 pieces of laying quail in each repetition. At the end of the period (85 days), after killing two quails from each repetition, the relative weight of thymus, spleen and bursa of fabricius and the liver enzymes activity indices such as albumin, alkaline phosphatase (ALP), alanine transaminase (ALT) and aspartate transaminase (AST) were investigated. Dinitrochlorobenzene sensitization challenge test and response to the injection of mitogen phytohemagglutinin into the left wing web were studied. Sampling was done to evaluate the morphology of the intestinal tissue and the microbial flora population of the small intestine. To investigate the expression of MUC2 gene, samples from jejunum were collected and RT-PCR method was performed. The results showed that the consumption of supplemented diets caused a significant increase in the bursa.f relative weight (p ≤ 0.05) and a non-significant improvement of the liver enzyemes activity (p ≥ 0.05). The significant increase of beneficial microbial flora (Lactobacillus) and decrease of the colony population of (Escherichia coli and Salmonella enterica) bacteria in the intestine along with the increase in the surface of the villi and the density of the number of goblet cells indicated the beneficial effects of the active compounds used in improving the health status of quails (p ≤ 0.05). Consuming supplemented diets with levels of vitamin E, sesamin and thymoquinone caused an increase in MUC2 mRNA expression in the intestine. The results showed the benefits of vitamin E, sesamin and thymoquinone consumption on cell mediated mediated immunity, intestinal morphology, intestinal microbial flora and MUC2 mRNA expression in laying Japanese quails. Manuscript profile -
Open Access Article
36 - Comparison the Effects of Vitamin E and Propolis on Interleukin-5 and STAT1 Gene Expression in Wistar Rats with Non-alcoholic Fatty Liver Disease
Saeede Baarforoush Maryam Bananaj Ramin Hajikhani Hengameh AlibeikNonalcoholic fatty liver disease (NAFLD) is a growing health concern worldwide. Unfortunately, scientists have not succeeded in finding a suitable treatment method for this disease, and more research is needed. Studies have shown that treatment with antioxidants is effe MoreNonalcoholic fatty liver disease (NAFLD) is a growing health concern worldwide. Unfortunately, scientists have not succeeded in finding a suitable treatment method for this disease, and more research is needed. Studies have shown that treatment with antioxidants is effective in this disease. In this study, the effect of two different antioxidants on NAFLD induced in male Wistar rats was evaluated. This study was conducted on 32 male Wistar rats weighing 200 grams, which were randomly divided into four groups of eight. Mice were fed by gavage with high-fat emulsion at the rate of 2 mg/kg for 40 days. After suffering from fatty liver, the level of interleukin-5 (IL-5) in the serum was measured and also the expression level of STAT1 gene was determined using real-time PCR. The results showed that the level of serum IL-5 in the patient group significantly increased compared to the control group, and the treatment groups with vitamin E and propolis, significantly decreased the level of interleukin-5 compared to the patient group (p < 0.05). In addition, the greatest decrease was related to the propolis group (p < 0.05). On the other hand, the level of STAT1 gene expression in the fatty liver group is significantly increased compared to the control group (p < 0.05); Whereas, after treatment with antioxidants, the expression of this gene decreased (p < 0.05). Based on the obtained results, the use of propolis and also vitamin E as natural antioxidants by reducing the inflammatory interleukin and also reducing the expression of genes effective in the formation of NAFLD, have a promising therapeutic role in non-alcoholic fatty liver disease. Manuscript profile -
Open Access Article
37 - Comparing the Effect of Turmeric and Vitamin E in the Improvement of Lipid Profile and Biochemical Markers of Liver and Kidney in Japanese Quails
Majid Gholami-AhangaranThe present study aimed to investigate effect of turmeric on the biochemical markers of liver and kidney in Japanese quail. For this purpose, 180 one-day Japanese quails were divided randomly into four groups with three repetitions. They were grown since one day t MoreThe present study aimed to investigate effect of turmeric on the biochemical markers of liver and kidney in Japanese quail. For this purpose, 180 one-day Japanese quails were divided randomly into four groups with three repetitions. They were grown since one day to 42 days under similar conditions. All groups applied the basic standard diet based on the NRC recommendation. Group 1 received basic diet with 0.5 % turmeric. Group 2 received basic diet with 1% turmeric. Group 3 received basic diet with 0.25 % vitamin E. Group 4 as the control group used basic diet. All quails were slaughtered at the age of 42 days and serum samples were collected for evaluating the cholesterol, HDL, LDL, triglyceride, total protein, uric acid and liver enzyme (ALT and AST) levels. The result of the previous study indicated that using turmeric at the level of 0.5 and 1% at the diet of quail is equal to all markers of Triglyceride metabolism, cholesterol and protein as well as the markers related to the evaluation of liver and kidney function by adding vitamin E. In general, a relative improvement was observed in the mentioned markers than the control group. Data comparison showed that using turmeric at the level of 1% had better effects than adding 0.5 % turmeric in most cases. It seems that using turmeric in the diet of quail can improve the markers related to fat metabolism. Manuscript profile
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