The effect of vitamin E and selenium on serum injection on serumic levels of T3 and T4 hormones in the Arabian horse

Subject Areas : Veterinary Clinical Pathology

بهرام Amouoghli-Tabrizi ¹ , A. Hassanpour ² , M. Khakpour ³ , Y. Mohamadpour-Tanha ⁴

1 - Department of Clinical Sciences, Faculty of Veterinary Medicine, Islamic Azad University, Tabriz Branch, Tabriz, Iran.
2 - Department of Clinical Sciences, Faculty of Veterinary Medicine, Islamic Azad University, Tabriz Branch, Tabriz, Iran.
3 - Department of Microbiology, Faculty of Veterinary Medicine, Islamic Azad University, Tabriz Branch, Tabriz, Iran
4 - Graduate of Veterinary Medicine, Islamic Azad University, Tabriz Branch Tabriz, Iran

Received: 2008-11-13 Accepted : 2009-01-19 Published : 2008-08-22

Keywords: vitamin E and selenium, Arabian horse, Thyroid hormones (T3, T4),

Abstract :

     This study was conducted evaluate the effect of vitamin E and Selenium injection on serumic levels of thyroid hormones in the Arabian horse. Twelve Arabian stallions of approximately equal age were selected and based on their age (4 and 5 years old), allocated to tow groups each consisting of six animals. In each group, three of the six horses were injected by vitamins E and selenium at a dose rate of 1cc/30 kg intramuscularly every tow days and the other three animals which were chosen as the controls were similarly injected by normal saline solution. Two days alter each injection; blood samples of the horses in each group were collected using venoject from the jugular vein. After separating the blood serum by centrifuging, the levels of T3 and T4 were measured using the ELISA technique. Following the first injection, the serumic levels of thyroid hormones demonstrated a significant increase in comparison with the controls (p<0.05) while after the second injection, the serumic levels of T3 and T4 had decreased to normal values similar to the control groups. However, following the third injection the decreased in T3 and T4 levels was clearly evident and statistically significant (p<0.05). According to the results of the present study, the injection of vitamin E and selenium for more than twice leads to decrease in the seumic levels of T3 and T4 hormones of the horse and this is coupled with reduction of the basic body metabolism which is not beneficial for the animal.

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