The effect of a course of forced swimming exercises with vitamin E on the histopathology of uterine tissue in endometriosis model rats
Subject Areas : Physical Activity and Health
Shahrbano jaafari
1
,
Hajar Abbaszadeh
2
,
parvin farzanegi
3
,
Leila zameni
4
1 - Ph.D Candidate, Department of Physical Education and Sports Science, Sari Branch, Islamic Azad University, Sari, Iran
2 - Associate Professor, Department of Physical Education and Sports Science, Sari Branch, Islamic Azad University, Sari, Iran
3 - Associate Professor, Department of Physical Education and Sports Science, Sari Branch, Islamic Azad University, Sari, Iran
4 - Assistant Professor , Department of Physical Education and Sports Science, Sari Branch, Islamic Azad University, Sari, Iran
Keywords: vitamin E, Swimming, Histopathology, Endometriosis,
Abstract :
Purpose: The purpose of this study was to investigate the effect of a course of swimming exercises with vitamin E on the histopathology of uterine tissue in endometriosis model rats. Method: This study was of an experimental type, in which the number of 5 8-week-old female Wistar rats after the induction of the model was randomly divided into 5 healthy control groups, endometriosis, endometriosis+ vitamin E, endometriosis+swimming, endometriosis+swimming+Vitamin E were divided. The amount of vitamin consumption was 200 mg/kg per body weight of each rat, and the swimming training program was for 8 weeks, five days a week, and every day for 30 minutes. After anesthesia, an autopsy was performed and uterine tissue samples were taken. Histological results obtained from uterine tissue samples were expressed descriptively with pictures. Findings: The results showed that in the rats of the endometriosis model, the cylindrical epithelium had completely disappeared and was only visible in some areas compared to the control group. On the other hand, in the vitamin and exercise groups, although the size of the cyst was reduced, the structure of the epithelium was not completely normal. However, blood sampling of the tissue was done well and vessels were visible around the tissue. On the other hand, it was observed that the light-colored areas indicated the induction of tissue death in the layers around the cyst, and these symptoms could be considered as a reason for the shrinking of the cyst size and its removal in the future. Conclusion: It seems that performing swimming exercises and taking vitamin E at the same time can help reduce tissue damage and improve the histopathological factors of uterine tissue in endometriosis model rats.
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