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Open Access Article
1 - Evaluation of the Antioxidant Activity of Some Rosaceae Plants as an Alternative to the Synthetic Antioxidants in Food Industry
فائزه Kamali A.R Sadeghi Mahonak زهرا Nasiri farIntroduction : The applications of natural antioxidants with medicinal values are growing in the preventive medicine and food industries. This study investigates the antioxidant ability of five species of Rosaceae family and compares the activities with the synthe MoreIntroduction : The applications of natural antioxidants with medicinal values are growing in the preventive medicine and food industries. This study investigates the antioxidant ability of five species of Rosaceae family and compares the activities with the synthetic antioxidants BHT, BHA as well as the natural ascorbic acid. Materials and Methods : In this study, the phenolic content of the methanolic extract of the samples were isolated and the antioxidant activities of five species of Rosaceae were determined by using DPPH free radical and nitric oxide scavenging , and the results were compared to the synthetic antioxidant Results : The results showed that the content of studied plant samples ranged from 0.51±0.41 – 35.53±0.89 mgGAEg -1. Concentraition of extract for scavening 50 percent of free radicals and nitric oxide radicals varied from 77.42 ± 0.91 to 1484.2 ± 96.44 and 233.24±3.39- 1572.46±203.76 Ug/ml. The highest phenolic amount was related to the Rosa damascena Mill leaf and next grade Cydonia oblonga Mill leaf. Extract of damask Rose, Quince leaves, damask Rose petals, Quine fruit and seed and Almond seed had high antioxidant activity and no significant difference was observed between them and the synthetic antioxidants (BHT, BHA and Vit C). Conclusion : The results of this study clearly suggested that there is a significant relationship between the antioxidant activity and the phenolic concentration and the extracts of damask Rose, Quince leaves, damask Rose petals, Quince fruit and seed and almond seed might be employed as appropriate alternatives to the synthetic antioxidants. Manuscript profile -
Open Access Article
2 - The Impact of Short-Term Garlic Supplements on Serum Total Antioxidant Capacity and Malondialdehyde in Active Men after Eccentric Exercise
A. Sadeghi M. GholamiIntroduction: Garlic increases the antioxidant levels of the body. The antioxidant defensive system in the body can reduce the oxidative stress and reduces the damage to the cells. The aim of this study is to investigate the effects of short-term supplementation of garl MoreIntroduction: Garlic increases the antioxidant levels of the body. The antioxidant defensive system in the body can reduce the oxidative stress and reduces the damage to the cells. The aim of this study is to investigate the effects of short-term supplementation of garlic on the total anti-oxidative capacity, malondialdehyde serum in active men after eccentric exercise. Materials and Methods: Twenty healthy athlete males (age of 24 ± 3 years, body mass index of 24.4±1.3 kg.m-2, and VO2 max of 49.1±3.2 ml/kg/min) were randomly assigned to two equal groups: experimental (daily intake of 700 mg garlic capsules) and control (placebo) groups who used dextrose capsules for four weeks. The blood samples were taken at baseline, after completing a four-week period supplementation and after eccentric exercise (45 minutes of running with 9 set of 5-minutes with 80% oxygen consumption and 10% with a negative slope between each set of 2 minute active recovery with zero slopes). The parameters were analyzed using repeated measure ANOVA, Bonferroni, with a significance level of a=0.05. Results: Garlic supplementation for four weeks increased the total antioxidant capacity in the pre exercise (P<0.05) significantly, but decreased after downhill running in two groups (P <0.05). Garlic supplementation did not have any effects on Malondialdehyde, therefore, there are not any significant differences between Malondialdehyde after supplementation among the two groups, but increased after downhill running in two groups. Conclusion: Garlic supplementation might reduce oxidative stress damage by increasing of TAC after eccentric exercise in active men. Manuscript profile -
Open Access Article
3 - Isolation of Shahmirzadi Husk Walnut Extract Using Microwave Assisted Extraction (MAE) and Evaluation of its Antioxidant Activity
S. Rezai Erami S.M. Jafari M. Khamiri H. BayatIntroduction: Doubts about the safety and health hazard concerned with the use of synthetic antioxidants have led to a growing demand for the application of natural antioxidants. Materials and Methods: In this study the antioxidant activities of water and alcoholic ext MoreIntroduction: Doubts about the safety and health hazard concerned with the use of synthetic antioxidants have led to a growing demand for the application of natural antioxidants. Materials and Methods: In this study the antioxidant activities of water and alcoholic extracts of shahmirzadi variety of green husk of walnut based on reducing power, total antioxidant activity and DPPH scavenging activity were evaluated. The effects of extracts on inhibition of oxidation chain reactions of soyabean oil was examined by measuring peroxide and thiobarbitoric acid values as means to evaluate the antioxidant activities. Phenolic compounds were extracted with methanol (80%), ethanol (50%) and water and the total phenolic content was measured by Folin-Ciocalteu method. Results: The results showed that the highest total phenolic compounds were present in the methanolic extract using microwave. The results also indicated that the extracts were able to retard the oxidation and the antioxidant activity was concentration dependent and the sample with the concentration of 1000ppm extract inhibited the oxidation of soyabean oil. Conclusion: Walnut husk might be regarded as a potential source of natural antioxidants but further investigation might be recommended for its possible application in food and related industries. Manuscript profile -
Open Access Article
4 - Investigating the effect of nanoparticles with antioxidant properties on free radicals
Fatemeh Moradi Nadia Mahmoudi KhatirObjectives: The purpose of this study is to investigate the effect of nanoparticles with antioxidant properties on free radicals.Materials and methods: In order to achieve the goal of the research, the content and results of valid research articles related to the subjec MoreObjectives: The purpose of this study is to investigate the effect of nanoparticles with antioxidant properties on free radicals.Materials and methods: In order to achieve the goal of the research, the content and results of valid research articles related to the subject of the current research have been analyzed and reviewed.Findings: Examining and analyzing the results of studies that have dealt with the effect of nanoparticles with antioxidant properties on free radicals, showed that nanoparticles have recently received much attention due to their many applications and unique properties. Oxidative stress is the cause of many diseases in humans. Oxidative stress is a phenomenon in which the balance between antioxidant defense and oxidants in the cell is disrupted. Antioxidants prevent damage caused by oxidants. Although antioxidants have been known for a long time, research on improved natural or synthetic antioxidants is still a topic of interest due to their important practical applications. Antioxidants may suffer from low stability under oxygen and in biological systems can be degraded before reaching their target sites; Or they can have adverse health effects that limit their use. Sometimes, it is desirable to remove the antioxidants from the homogenous system to which they have been added, after they have taken effect. In this context, nanotechnology has opened new opportunities to exploit the unique and innovative properties of nanomaterials, possibly in combination with some common natural or synthetic compounds, with the aim of achieving pioneering "nano-antioxidants" with enhanced properties. Some nanomaterials, including organic metal oxides (e.g., melanin, lignin) (i.e., cerium oxide) or metal nanoparticles (e.g., gold), exhibit intrinsic redox activity, often by scavenging radicals and/or It is associated with superoxide dismutase-like and catalase.Conclusions: Inorganic nanoparticles have been successfully evaluated in terms of antioxidant properties. Recently, nano antioxidants have shown the ability to reduce oxidative stress with greater sensitivity, cellular antioxidant activity and minimal cytotoxic effects and targeted delivery. Manuscript profile -
Open Access Article
5 - Evaluation Of the effects Of a cell permeable antioxidant on motility and membrane integrity during liquid storage Of goat semen
Abdollah Abid Mohsen Forozanfar Seyyed Morteza Hosseini mehdi Hajian Mohammad Hosain Nasr EsfahaniInroduction and Objective: present study was aimed to evaluate the effects of addition of a synthetic antioxidant, MnTE, on motility and membrane integrity during the liquid storage (up to 72h) of goat semen.Materials and Methods:Semen samples were collected using artif MoreInroduction and Objective: present study was aimed to evaluate the effects of addition of a synthetic antioxidant, MnTE, on motility and membrane integrity during the liquid storage (up to 72h) of goat semen.Materials and Methods:Semen samples were collected using artificial vagina from three mature goats, mixed and diluted (1:20 v/v) with a Bioxell extender containing 0 (control), 0.01, 0.1 and 1 µM of MnTE. All diluted sperm suspensions were cooled to 5°C and stored until 72hr and sperm motility and membrane integrity were assessed in 0, 12, 24, 36, 48 and 72hr post dilution.Results: With increasing storage time (0 to 72h), the percentage of motility and membrane integrity decreased in all treatments and control group. Addition of MnTE at 0.01 and 0.1 µM concentration to the extender, improved goat semen quality, while addition of 1µM of MnTE had an adverse effect on motility and membrane integrity when compared to control.Conclusion: extender supplemented with MnTE could reduce the oxidative stress provoked by liquid storage processes. The optimum concentration of MnTE seems to be 0.01 and 0.1µM for goat semen in liquid storage state. However, further supplementation of extender with 1µM of MnTE not only did not improve the results but inversely affected motility and membrane integrity in all treatment group. Manuscript profile -
Open Access Article
6 - A review of the antioxidant compounds of plant sources in Iran
seyyed moein nazari mohammad malekiAntioxidants are compounds that delay oxidation in low concentrations. They are divided into two categories: natural and synthetic. The most used antioxidant groups in the food industry are synthetic phenolic antioxidants BHA, BHT, TBHQ and PG. These antioxidants are vo MoreAntioxidants are compounds that delay oxidation in low concentrations. They are divided into two categories: natural and synthetic. The most used antioxidant groups in the food industry are synthetic phenolic antioxidants BHA, BHT, TBHQ and PG. These antioxidants are volatile and sensitive to heat and are not favorable for food stability, on the other hand, their use threatens human health. For this reason, today scientists and researchers are trying to find natural compounds with antioxidant properties to replace natural antioxidants with synthetic antioxidants or to reduce their consumption. The results of the studies showed that plants are a rich source of phenolic compounds, flavonoids, tannins and other antioxidant compounds, which are the most important natural antioxidants.Nowadays, a wide group of plants and their extracts are considered as natural sources with antioxidant properties. The studies of carried out in Iran shows that edible and medicinal plants and their derivatives (essential oils, plant extracts) are widely used to prevent oxidative spoilage of food due to their strong and diverse antioxidant compounds. Among these, we can mention olive leaves, saffron petals, oregano, Froriepia subpinnata, Malva Sylvestris, Ferulago angulate, basil, hortensisj Sature, Salvia officinalis, turmeric, fennel, nettle, and black raspberry. Also, Dorema Aucheri, thyme, cinnamon and pomegranate peel have medicinal and therapeutic properties. Heizah grass plant is recommended as a health-giving and stabilizing combination of oils due to its easy access and cost-effectiveness in Iran. Manuscript profile -
Open Access Article
7 - Determination of total antioxidant capacity with nanoparticles
Safieh MomeniTotal antioxidant capacity (TAC) as the cumulative activity of antioxidants in a sample is an important parameter in the analysis of biological or food matrices. Therefore, it is very important to evaluate the total antioxidant capacity of the substances in the diet and MoreTotal antioxidant capacity (TAC) as the cumulative activity of antioxidants in a sample is an important parameter in the analysis of biological or food matrices. Therefore, it is very important to evaluate the total antioxidant capacity of the substances in the diet and biological fluids. Based on this, many methods check their antioxidant capacity and effectiveness in different conditions. However, there is often no strong correlation between the capacities measured on the same materials with different methods, which is due to the variety of active materials, mechanisms and different characteristics such as different types of antioxidants, the presence of other interfering substances in the sample, lack of participation of antioxidants are used in the method reaction. In recent years, different analytical methods based on nanoparticles have been developed to determine the antioxidant capacity of foods and plant materials.In these measurement methods, nanoparticles such as gold, silver, iron oxide, manganese oxide, quantum dots and cerium oxide have been used. In this article, we review some of the researches conducted in the field of total antioxidant capacity measurement. Manuscript profile -
Open Access Article
8 - Synthesis of poly(maleic acid-co-acrylic acid) hydrogel for removing cadmium ion from sewage effluents and evaluation of thermodynamic and kinetic properties of its absorption.
Arman Samadzadeh Mamaghani Mohammadreza Manafi Mohammad HojjatiPMA-AA hydrogel was synthesized by copolymerizing acrylic acid and maleic acid by free radical polymerization and using methylene bis acrylamide crosslinker and ammonium persulfate initiator. It is an efficient adsorbent for removing Cd2+ ions from wastewater. The resul MorePMA-AA hydrogel was synthesized by copolymerizing acrylic acid and maleic acid by free radical polymerization and using methylene bis acrylamide crosslinker and ammonium persulfate initiator. It is an efficient adsorbent for removing Cd2+ ions from wastewater. The resulting hydrogel was evaluated by infrared spectrometry and thermogravimetric analysis. The results of OH stretching vibration of AA and MA carboxylic functional groups showed a large and broad absorption band at 3000 cm-1. The C=O stretching frequency of the carboxyl group at 1631 cm-1 in PMA-AA hydrogel shifted to 1636 cm-1, these changes in frequency indicate that hydrogel adsorption is a chemical process. Thermogravimetric analysis of the unloaded PMA-AA hydrogel showed no weight loss up to 155 °C of the free gel, but at 190 °C, there was a significant weight loss, indicating hydrogel decomposition. This rapid weight loss for gels loaded with Cd2+ at 360°C indicated an increase in thermal stability of the loaded hydrogel. The maximum adsorption capacity for hydrogel -Cd2+ was determined to be 392.51 mg/g. The Langmuir isotherm provided the best explanation for the present result. This is because the surface of the hydrogel is homogeneous so its absorption is monolayer, the pseudo-second-order kinetic model explain the absorption well, and also the thermodynamic analysis shows that the absorption of Cd2+ on hydrogel is exothermic. The PMA-AA hydrogel loaded with Cd2+ ions was desorbed and still maintained the adsorption capacity of 99.30% after four adsorption-desorption cycles. Manuscript profile -
Open Access Article
9 - Evaluation Of Antioxidant And Anti-cancer Properties Of Purified Peptides From Enzymatic Hydrolysis Of Grape Seed
Mahnaz Samadi Varedehsara Peyman Ariayi Javad Hesari -
Open Access Article
10 - بررسی میزان آهن، ترکیبات فنلی و فعالیت آنتی اکسیدانی عصاره کنگر(Cirsium Congestum)
فاطمه علوی خوشحال اکرم شریفی -
Open Access Article
11 - بررسی خاصیت آنتی اکسیدانی و عملکردی پروتئین هیدرولیز شده دانه هندوانه توسط آنزیمهای تجاری
نسیم مهدوی میقان پیمان آریایی مهدی شریفی سلطانی سارا جعفریان -
Open Access Article
12 - Comparison of Bio- active Compounds of Iranian Black, Green and White Tea
Monireh Ranjbar Maryam Alinaghiyan -
Open Access Article
13 - ارزیابی تاثیر آنزیم های میکروبی و وزن مولکولی بر خاصیت آنتی اکسیدانی و ضد میکروبی پروتئین هیدرولیز شده دانه جو
نگار تاجیک پیمان آریایی لیلا نجفیان -
Open Access Article
14 - بررسی خواص فیزیکی، مکانیکی و آنتی اکسیدانی فیلم های خوراکی تولید شده از پولولان-نانورس حاوی نانو اسانس علف چشمه
محمد رضا عفیفی پیمان آریایی مهدی شریفی سلطانی سارا جعفریان -
Open Access Article
15 - Identification of Chemical Compounds in the Essential Oil of Salvia reuterana Bioss. and Evaluation of Antioxidant Properties and the Aamount of Phenols and Flavonoids in the Whole Plant Extract
Mohammad Hassan Mohammadi Behnam Mahdavi Hashem Akhlaghi Feiz Abad Hadis Farmanbar Jafar Abad -
Open Access Article
16 - The Effect of Hydrolysis Time and Enzyme Type on Antioxidant and Anti-cancer Activity of Hydrolyzed Clover Sprout Protein
Dina Mirsadeghi Darabi Peiman Ariayi Reza Safari Mohammad Ahmadi -
Open Access Article
17 - بررسی ویژگی های فیلم خوراکی بر پایه نانو سلولز باکتریایی اکسید شده با روش TEMPO حاوی پروتئین هیدرولیز شده حاصل از میوه درخت کاج
نجم الدین پیرویسی پیمان آریایی مهرو اسماعیلی محمد احمدی -
Open Access Article
18 - ارزیابی استخراج ترکیبات فنلی و آنتی اکسیدانی عصاره شقاقل تحت پیش تیمار فراصوت و حلال های ترکیبی
زهرا گرایلی اکرم شریفی هما بقایی -
Open Access Article
19 - فعالیت آنتی اکسیدانی مریم گلی، کلم قرمز، برگ گردو، اکلیل الملک و زالزالک در دماهای مختلف
محمد مؤمن هروی شهلا دانش مهر علی مرسلیمقدمه و هدف: گیاهان دارویی بدلیل نداشتن اثرات جانبی بسیار، می توانند جایگزین خوبی برای روش های مرسوم درمان سرطان شامل شیمی درمانی،پرتو درمانی و جراحی باشند. هدف از این مطالعه بررسی تاثیر دما در مهار رادیکال آزاد در دماهای مختلف می باشد. روش تحقیق:برای تعیین فعالیت Moreمقدمه و هدف: گیاهان دارویی بدلیل نداشتن اثرات جانبی بسیار، می توانند جایگزین خوبی برای روش های مرسوم درمان سرطان شامل شیمی درمانی،پرتو درمانی و جراحی باشند. هدف از این مطالعه بررسی تاثیر دما در مهار رادیکال آزاد در دماهای مختلف می باشد. روش تحقیق:برای تعیین فعالیت مهار کنندگی رادیکال آزاد با استفاده از عیارسنجی DPPH در دماهای مختلف دو تحقیق انجام شده است: ابتدا عصاره اتانولی مریم گلی، کلم قرمز، برگ گردو، اکلیل الملک و زالزالک به تنهایی و سپس مخلوط دوتایی از هر گیاه به منظور تعیین بر هم کنش های گیاه- گیاه. نتایج و بحث: به دلیل برهم کنش های گیاه- گیاه ، بیشترین در صد مهار رادیکال آزاد مربوط گیاهان به صورت تکی می باشد نه مخلوط. نتایج نشان دادند که با افزایش دما مهار رادیکال آزاد در حضور مریم گلی افزایش می یابد، در حالیکه در حضور زالزالک کاهش می یابد. بالاترین درصد مهار رادیکال آزاد در محدوده دمایی بین محیط تا دمای بدن وتب مربوط به مریم گلی در ˚C25 و بعد از آن مربوط به برگ گردو در˚C37 و در آخر زالزالک در ˚C40 می باشد. توصیه کاربردی/ صنعتی:نتایج دلالت دارند که بر جلوگیری از اثرات تداخلی (برهم کنش های گیاه- گیاه)، گیاهان دارویی به صورت دمنوش، غذا و میوه به تنهایی مصرف شوند. Manuscript profile -
Open Access Article
20 - فعالیت آنتی اکسیدانی عصاره متانولی .Salvia aethiopis L در سیستم گردش خون موش صحرایی
مصطفی اسدبگی رویا کرمیان پریسا حسنین مسعود رنجبر رامتین پاکزادمقدمه و هدف: رادیکال­های آزاد نقش مهمی را در گسترش آسیب­های بافتی در بیماری­های مختلف مانند سرطان، پیری، ضعف سیستم عصبی، ‏مالاریا، تصلب شرائین و رخدادهای پاتولوژیکی بازی می­کنند. آنتی­اکسیدان­ها نقش مهمی در ممانعت از پیشرفت این بیماری­ها Moreمقدمه و هدف: رادیکال­های آزاد نقش مهمی را در گسترش آسیب­های بافتی در بیماری­های مختلف مانند سرطان، پیری، ضعف سیستم عصبی، ‏مالاریا، تصلب شرائین و رخدادهای پاتولوژیکی بازی می­کنند. آنتی­اکسیدان­ها نقش مهمی در ممانعت از پیشرفت این بیماری­ها ‏ایفاء می­کنند. هدف از این مطالعه ارزیابی پتانسیل مهارکنندگی رادیکال آزاد ‏‎ DPPHدر سیستم گردش خون موش صحرایی ‏توسط عصاره متانولی ‏Salvia aethiopis‏ است. این گیاه متعلق به جنس مریم گلی از تیره نعناعیان است که اغلب گونه­های آن ‏ارزش غذایی و دارویی دارند. مطالعات بیشتر پتانسیل این گونه گیاهی را به عنوان یک کاندید مناسب جهت کاربردهای دارویی و صنعتی آشکار می­سازد. روش تحقیق: بدین منظور تعداد‎ ‎‏10‏‎ ‎سر‎ ‎موش‎ ‎صحرایی‎ ‎ماده‎ ‎بالغ‎ ‎به طور‎ ‎تصادفی‎ ‎با‎ ‎وزن‎ ‎حدود‎ ‎‏200-250 گرم انتخاب‎ ‎شده و سپس‎ ‎به طور‎ ‎مساوی‎ ‎و‎ ‎تصادفی‎ ‎به‎ ‎سه‎ ‎گروه‎ ‎تقسیم‎ ‎شدند. گروه اول موش­های ‏صحرایی 0/5 میلی لیتر‎ ‎محلول متانولی ‏DPPH‏ (4-10‏‏×3 مولار) دریافت‎ ‎کردند. گروه‎ ‎دوم موش­های صحرایی 1 ‏میلی­لیتر عصاره ‏Salvia aethiopis ‎‏ (1 میلی­گرم در میلی­لیتر) به همراه 0/5 میلی ‎لیتر محلول متانولی ‏DPPH‏ ‏دریافت کردند و گروه‎ ‎سوم موش های‎ ‎صحرایی 1 ‏میلی­لیتر اسید آسکوربیک را به جای عصاره گیاه به همراه 0/5 میلی ‎لیتر محلول متانولی ‏DPPH به عنوان کنترل مثبت دریافت کردند. ‏تمام تزریق ها به صورت درون صفاقی انجام شد. پس از خون­گیری از قلب حیوانات و جداسازی سرم، مقدار فعالیت ‏مهارکنندگی رادیکال آزاد DPPH توسط عصاره Salvia aethiopis با در نظر گرفتن کاهش جذب ‏قرائت شده به روش اسپکتروفتومتری ارزیابی شد.‏ نتایج و بحث: کاهش جذب برای رادیکال آزاد DPPH (1/85 نانومتر) در سرم خون موش­ها در حضور اسید آسکوربیک به عنوان کنترل مثبت (1/07 نانومتر) و عصاره متانولی Salvia aethiopis به عنوان نمونه (78/0 نانومتر) حاکی از توانایی مثبت مهارکنندگی رادیکال آزاد عصاره متانولی گونه مورد مطالعه در سیستم گردش خون موش­ صحرایی از اسید آسکوربیک به عنوان یک آنتی­اکسیدان سنتزی است. در مجموع نتیجه این مطالعه نشان می­دهد که عصاره Salvia aethiopisبه­دلیل دارا بودن فعالیت آنتی اکسیدانی مناسب می­تواند در مطالعات بالینی آتی مورد استفاده قرار گیرد. Manuscript profile -
Open Access Article
21 - Effect of low temperature stress on biochemical and physiological characteristics of some native genotypes of like-lime in the north of Iran
Saleh Mohammadi hamidreza khazaie Ahmad Nezami Yahya tajvarIn this study, the vulnerability of six native genotypes of like-lime (1-6 number) with control tolerant variety of Unshiu and sensitive variety of Persian lime (to low temperature) were studied low temperature stress ( 3, 0, -3 and -6˚C), on physiological responses, in MoreIn this study, the vulnerability of six native genotypes of like-lime (1-6 number) with control tolerant variety of Unshiu and sensitive variety of Persian lime (to low temperature) were studied low temperature stress ( 3, 0, -3 and -6˚C), on physiological responses, in a completely randomized design with Tukey´s mean comparison. Analysis of variance showed that in the interaction between genotype and temperature, leaf water soaking, electrolyte leakage, lipid peroxidation, proline content and antioxidant capacity were significant. It was while in reaction of temperature and genotype, total carbohydrates, chlorophyll a, b, total and Carotenoids have not significant differences. Therefore, in comparison of data, the highest of leaf water soaking (91/628%), electrolyte leakage (99.3%) and lipid peroxidation (3.32 µgr/gr FW) were recorded in control sensitive plant (Persian lime) at temperature of -6˚C. Versus, the highest proline content (32.006 mg/gr leaf fresh Weight) and antioxidant capacity (73.36%) were observed in control tolerant plant (Unshiu) at temperature of -3˚C. It is noteworthy that total carbohydrate, chlorophyll a and total, were significantly different only under the influence of genotype factor. Accordingly, the maximum amount of chlorophyll a (2.359 mg/gr leaf fresh Weight), total chlorophyll (2.932 mg/gr leaf fresh Weight) and total carbohydrate (33.486 mg/gr leaf fresh Weight) were measured in in control tolerant plant (Unshiu). It should be noted that among the six native genotypes of like-lime studied, different reactions were recorded under low temperature. So that after control tolerant plant (Unshiu), native genotypes like-lime No. 6 showed better resistance against low temperature stress. Manuscript profile -
Open Access Article
22 - The Effects of Hydroalcoholic Extract of Salvia officinalis on Liver Tissue and Cu, Fe, Zn and Mg Elements in Male Rats
شهرزاد خاکپور مریم خسروی معصومه میرزائی محیا نجاریThe imbalance between the production of free radicals and antioxidant can be the cause of oxidative stress.Oxidative stress induces different diseases and tissue damages. Isoniazid has been used for the purpose of producing free radicals. In the present study, we invest MoreThe imbalance between the production of free radicals and antioxidant can be the cause of oxidative stress.Oxidative stress induces different diseases and tissue damages. Isoniazid has been used for the purpose of producing free radicals. In the present study, we investigated the effects of Salvia officinalis hydroalcoholic extract on blood elements such as Fe, Mg, Zn and Cu. In this study, 63 male rats were used and divided in 9 groups; in each group 7 rats were included. Isoniazid 50mg/kg was orally administered to rats continuously once per day for 28 days using a feeding atraumatic needle. The experimental groups received for 28 days,Salvia officinalis hydroalcoholic extract with the doses 100, 250 and 400 mg/kg intraperitoneally, and also some experimental groups were coadministered with different doses of the extract and isoniazid; the results of serum Fe, Mg, Zn and Cu were compared with the control and sham groups, as well. Also, the animal livers of all groups were separated and dissected for the histopathological studies. Zn and Cu were increased significantly in the treated-groups with Salvia officinalis, but the levels of Fe and Mg showed a significant decrease in the experimental groups treated with all the doses of Salvia officinalis hydroalcoholic extract. It seems that tannin and bitter compounds of Salvia officinalis hydroalcoholic extract are the main agents to alternate the blood element levels. Manuscript profile -
Open Access Article
23 - Evaluating the Effect of Coenzyme Q10 (CoQ10) on Fertility, Depression, and Anxiety in Male Rats
Maryam Sharafi chie Ramin Hajikhani Jalal Solati Maryam khosraviQuenzim Q10 (CoQ10) is a benzoquinone compound soluble in androgen lipid found in most tissues of the body. CoQ10 has a potent antioxidant activity and neutralizes free radicals. The aim of this study was to investigate the effect of CoQ10 as a potent antioxidant and fr MoreQuenzim Q10 (CoQ10) is a benzoquinone compound soluble in androgen lipid found in most tissues of the body. CoQ10 has a potent antioxidant activity and neutralizes free radicals. The aim of this study was to investigate the effect of CoQ10 as a potent antioxidant and free radicals neutralizer on reproductive disorders, sexual behaviors, anxiety, and depression in male rats. In this study, small male rats (weight range of30-35 g) were used. At first, the animals under study passed a two-week treatment period. The adult male rats were treated with doses of 200, 300, 400 mg/kg of CoQ10 for two weeks. Then the effects of the given treatment were studied in the physiologic section. After the end of the treatment period, the sexual behaviors were assessed in the control group and treated groups by sexual behavior test. Then, the anxiety and depression levels in adult male rats were assessed using EPM and forced swimming tests, respectively. The findings of this study showed that the prescription of CoQ10 alone did not have a significant effect on sexual behaviors, depression, and anxiety in male rats. Manuscript profile -
Open Access Article
24 - The effect of different urea rates on some morphological and phytochemical traits of artichoke
Marziyeh Allahdadi Laleh Mosharraf Broujeni2Proper application of N fertilizer and its optimization in plants is definitely important. To study the effect of different level of nitrogen fertilizer on some morphological and phytochemical traits of artichoke, an experiment was conducted in a randomized complete blo MoreProper application of N fertilizer and its optimization in plants is definitely important. To study the effect of different level of nitrogen fertilizer on some morphological and phytochemical traits of artichoke, an experiment was conducted in a randomized complete block design with three replications in field conditions during two consecutive years in Isfahan, Iran. Nitrogen fertilizer was applied in 100, 150, and 200 kg/ha net nitrogen from urea source. Morphological traits including stem height, number of leaves per plant and number of capitols per plant and phytochemical traits such as total phenol, total flavonoid and antioxidant activity were measured. Increasing of urea fertilizer rate from 0 to 200 kg/ha increased stem height, number of leaves and capitols per plant, but decreased total phenol and flavonoid and antioxidant activity. Although nitrogen is an essential element for growth and development of artichoke plant, the consumption of high levels of nitrogen fertilizer has negative effect on qualitative traits. Also, considering chemical fertilizers hazard in environment, it is recommended to use 100 kg/ ha N to achieve optimal yield in artichoke. Manuscript profile
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