فعالیت آنتی اکسیدانی مریم گلی، کلم قرمز، برگ گردو، اکلیل الملک و زالزالک در دماهای مختلف
Subject Areas : Journal of Medicinal Herbs, "J. Med Herb" (Formerly known as Journal of Herbal Drugs or J. Herb Drug)محمد مؤمن هروی 1 , شهلا دانش مهر 2 , علی مرسلی 3
1 - گروه شیمی فیزیک، دانشگاه آزاد اسلامی واحد مشهد، مشهد، ایران
2 - گروه شیمی فیزیک، دانشگاه آزاد اسلامی واحد مشهد، مشهد، ایران
3 - گروه شیمی فیزیک، دانشگاه آزاد اسلامی واحد مشهد، مشهد، ایران
Keywords: سرطان, گیاه دارویی, رادیکال آزاد, فعالیت مهارکنندگی,
Abstract :
مقدمه و هدف: گیاهان دارویی بدلیل نداشتن اثرات جانبی بسیار، می توانند جایگزین خوبی برای روش های مرسوم درمان سرطان شامل شیمی درمانی،پرتو درمانی و جراحی باشند. هدف از این مطالعه بررسی تاثیر دما در مهار رادیکال آزاد در دماهای مختلف می باشد. روش تحقیق:برای تعیین فعالیت مهار کنندگی رادیکال آزاد با استفاده از عیارسنجی DPPH در دماهای مختلف دو تحقیق انجام شده است: ابتدا عصاره اتانولی مریم گلی، کلم قرمز، برگ گردو، اکلیل الملک و زالزالک به تنهایی و سپس مخلوط دوتایی از هر گیاه به منظور تعیین بر هم کنش های گیاه- گیاه. نتایج و بحث: به دلیل برهم کنش های گیاه- گیاه ، بیشترین در صد مهار رادیکال آزاد مربوط گیاهان به صورت تکی می باشد نه مخلوط. نتایج نشان دادند که با افزایش دما مهار رادیکال آزاد در حضور مریم گلی افزایش می یابد، در حالیکه در حضور زالزالک کاهش می یابد. بالاترین درصد مهار رادیکال آزاد در محدوده دمایی بین محیط تا دمای بدن وتب مربوط به مریم گلی در ˚C25 و بعد از آن مربوط به برگ گردو در˚C37 و در آخر زالزالک در ˚C40 می باشد. توصیه کاربردی/ صنعتی:نتایج دلالت دارند که بر جلوگیری از اثرات تداخلی (برهم کنش های گیاه- گیاه)، گیاهان دارویی به صورت دمنوش، غذا و میوه به تنهایی مصرف شوند.
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