Introduction & Objective: Adiponectin with properties similar to exercise increases glucose uptake in muscle and decreases glucose production in the liver. Cinnamon has modulating properties against oxidative stress, blood sugar and obesity. Therefore, considering t More
Introduction & Objective: Adiponectin with properties similar to exercise increases glucose uptake in muscle and decreases glucose production in the liver. Cinnamon has modulating properties against oxidative stress, blood sugar and obesity. Therefore, considering the effect of exercise training on adiponectin gene expression, the effect of high-fat diets on obesity and the effects of cinnamon on weight loss, the present study seeks to answer the question whether six weeks of aerobic exercise and cinnamon extract on adiponectin gene expression in Fat and liver tissues and the mass of these tissues have different effects in male rats fed with a high-fat diet.Materials & Methods: The present study was conducted in the form of a multi-group research project with a control group the average of the research variables among the groups were compared using one-way analysis of variance and Bonferroni supplementary test and independent t-tests and two-way analysis of variance at the significance level p ≥ 0.05 for all tests with the aim of determining the differences between the groups.Results: The results showed the effect of high-fat diet on adverse changes in adiponectin gene expression in adipose tissue and liver, body weight and weight of adipose tissue and liver. Performing aerobic exercise alone, consuming cinnamon extract alone and the interaction of aerobic exercise and cinnamon extract caused favorable changes in the expression of adiponectin gene in adipose tissue and liver and the weight of adipose tissue and liver compared to the high-fat diet group.Conclusion: It seems that from the desirable and accepted physical activities and sports exercises on the Adipose tissue and liver, maybe some food intakes such as cinnamon supplement extract combined with sports exercises have synergy with useful exercises.
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Adiponectin is a type of adipokine that is involved in sugar and lipid metabolism, this adipokine is in addition to the tissue that it is like and can become. The present study was designed to compare the effect of endurance, resistance and combined exercises on the lev More
Adiponectin is a type of adipokine that is involved in sugar and lipid metabolism, this adipokine is in addition to the tissue that it is like and can become. The present study was designed to compare the effect of endurance, resistance and combined exercises on the level of adiponectin gene expression in the hand and leg muscles of Wistar rats.The current study is an experimental research in which 40 healthy male Wistar rats were divided into four ten groups of control, resistance training, endurance and combined. Each group did their own exercises for 8 weeks. Finally, hand and foot muscles were examined to measure the adiponectin gene. The results of the analyzes showed that the level of adiponectin gene expression was different among all groups (P < 0.001). The relative expression of adiponectin gene in all training groups increased significantly compared to the control group (P < 0.001).Also, comparing exercise groups together, combined exercises had the greatest effect and resistance exercise had the least effect. In intra-group comparison, adiponectin gene expression was higher in hand muscle than leg muscle during resistance training (P = 0.047), but gene expression was higher in leg muscle during endurance training (P = 0.029). These two muscles were not significantly different during combined training (P = 0.086). According to the results of this study, all types of sports training can increase the expression of adiponectin gene, but combined, endurance and resistance training have the greatest effect, respectively.
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Abstract Introduction:Fat is one of the most important components of human diet. The human body needs fats to perform its daily activities. In case of eating a lot of carbohydrates, inactivity or genetic factors, some people have obesity problem. Obesity and overweight More
Abstract Introduction:Fat is one of the most important components of human diet. The human body needs fats to perform its daily activities. In case of eating a lot of carbohydrates, inactivity or genetic factors, some people have obesity problem. Obesity and overweight are relatively dangerous diseases. The production of vinegar from various materials has been of interest for a long time, and it is used as an effective drink for weight loss. The purpose of this research is to investigate the effect of vinegar prepared from button mushrooms on obesity. Methods: 12 eight-week-old male Wistar rats became obese during 4 weeks with high feeding and low exercise. The effect of edible mushroom vinegar during 2 weeks on obesity with three treatments (control group (VS) boiled vinegar group ml2 (V1), boiled vinegar group ml 1 (V2) and raw vinegar group ml 2 (V3) per kilogram of weight) was investigated. Vinegar treatment was directly entered into the stomach of rats with the help of long gavage needles. Results: All treatments caused significant (p<0.01) weight loss. A number of genes effective in the production of fat in the liver were investigated. Increasing GLUT4 gene expression was effective in preventing lipogenesis in all treatments of obese rats with overeating. The increase in PPAR gene expression was not significant. Increasing the expression of Adiponectin gene was effective in increasing lipolysis in all treatments of obese rats with overeating, While the increase in LPL gene expression was not significant. All 3 mushroom vinegar treatments had a positive effect on the reduction of renal enzymes ALT and ALP. V2 treatment of mushroom vinegar reduced cholesterol and triglycerides. Discussion: It was found that edible mushroom vinegar causes weight loss and also has positive protective effects on the liver.
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In recent years, special attention has been paid to insulin resistance mediators, such as adiponectin, that is produced and expressed during conception in placental tissue, thereby inducing its effects on the growing embryo and the health of the mother.In this study, th More
In recent years, special attention has been paid to insulin resistance mediators, such as adiponectin, that is produced and expressed during conception in placental tissue, thereby inducing its effects on the growing embryo and the health of the mother.In this study, the effect of selenium nanoparticles and sodium selenite on transcription of placental adiponectin gene was investigated for the first time during the transitional period. For this purpose, 20 pregnant ewes were selected randomly. During the 10 days leading up to birth, oral administration of selenium nanoparticles (Se NPs) with dosages of 0.05 and 0.10 mg/kg B.W. and sodium selenite with dosage of 0.1 mg/kg B.W. was performed. At the same time, the control group received equal volume of distilled water. At parturition, placental samples were collected and the transcription rate of adiponectin gene was determined by using RT-PCR based on a comparison assay of 2-ΔΔCt.The results showed that selenium supplementation in pregnant ewes leads to a significant reduction in adiponectin gene transcription rate and the suppressive role of selenium nanoparticles was significantly superior to sodium selenite.
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Adiponectin is a peptide hormone that is secreted from adipose tissue in humans and is effective on fat and glucose metabolism. Interleukin-6 also has the main role in various types of host defense mechanisms, including immune reactions and acute phase reactions. Theref More
Adiponectin is a peptide hormone that is secreted from adipose tissue in humans and is effective on fat and glucose metabolism. Interleukin-6 also has the main role in various types of host defense mechanisms, including immune reactions and acute phase reactions. Therefore, the aim of the present study was to compare the short-term effects of aerobic exercise and high-fat diet and curcumin extract on the expression of adiponectin and interleukin genes in six muscle tissues of male Wistar rats. For this purpose, 50 two-month-old male rats were prepared and divided into five control groups, high-fat diet, curcumin and high-fat diet, exercise and high-fat diet, curcumin + exercise + high-fat diet. Data analysis was compared using one-way analysis of variance. The mean of intra-group differences was also compared using the one-way statistical test. The results showed that the average expression of the adiponectin gene of the subjects showed a significant difference among the 5 groups. The results of Bonferroni's post hoc test also showed a significant difference between the control group and other groups. Also, the expression of interleukin 6 gene increased in two groups - high-fat diet and high-fat + curcumin diet group compared to the control group. But in two groups of high-fat diet + exercise and high-fat diet + exercise + curcumin group, there was a significant decrease.
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