The effect of 8 weak HIIT training on adiponectin gene expression in obese rats
Subject Areas : Exercise Physiology and Performance
sajad arshadi
1
,
zahra mohamadpour rodbaraki
2
1 - Department of exercise physiology, islamic azad university south tehran branch
2 - Department of exercise physiology, islamic azad university sari branch
Keywords: Obesity, Adiponectin, high intensity interval training (HIIT),
Abstract :
Background: Obesity is the result of accumulation of excess adipose tissue due to an imbalance between food intake and energy intake. Exercise can play an effective role in reducing adipose tissue due to increased energy consumption. The aim of this study was to investigate the effect of high intensity training (HIIT) on adiponectin levels in adipose tissue in rats on a high fat diet.Methods: For this purpose, 32 rats with a lifespan of 8 weeks were randomly divided into 3 groups: obese and HIIT, obese without HIIT and normal weight. The HIIT training program was performed for eight weeks. At the end of the training period, the rats were anesthetized. The subcutaneous adipose tissue of the animal was also sampled and qRT-PCR analysis was performed to evaluate the expression of adiponectin gene.Results: The results showed that adiponectin gene expression decreases under the influence of obesity. But with HIIT training and reduced obesity, its expression increases.Conclusion: In general, the results of this study showed that HIIT training can reduce obesity, increase adiponectin gene expression in animals with high fat diet.
1-Khodadadi Hashem, Rajabi Hamid, Atarzadeh Hosseini Seyed Reza, Abbasian Sadegh The effect of intense intermittent exercise and pilates on serum irisin levels and insulin resistance in overweight women. Iranian Journal of Endocrinology and Metabolism. Shahid Beheshti University of Medical Sciences and Health Services. 2013:16,196-190. https://ijem.sbmu.ac.ir/browse.php?a_id=1709&sid=1&slc_lang=en
2-Kazemi Abdulreza, Amani Sadegh, Sayyed Yazdi Sayyed Rasool. The effect of intense interval training on the levels of adiponectin, insulin and plasma glucose in male rats. Scientific Journal of Ilam University of Medical Sciences. 2015: 24, Number 1. https://sjimu.medilam.ac.ir/browse.php?sid=1&a_id=4904&slc_lang=en
3-Tawfighi Asghar. Effect of water exercise on serum adiponectin level and insulin resistance in obese postmenopausal women. Iranian Journal of Endocrinology and Metabolism. Shahid Beheshti University of Medical Sciences and Health Services. 2011: 12, 267-260. https://ijem.sbmu.ac.ir/article-1-849-en.html
4-Najmi Mehtab, Haji Farji Majid, Abd Mishani Mahshid. The role of adipokines secreted from adipose tissue on the immune system in obese people. Journal of Nutritional Sciences and Food Industries of Iran. 2013: 5, 896-887. URL: http://nsft.sbmu.ac.ir/article-1-1089-en.html
5-Souri Rahman, Akbari Mina, Kazemi Abdul Reza, Saee Mohammad Amin, Amani Sadegh. Effect of high intensity interval training (HIIT) on serum levels of adiponectin and leptin in obese children. Sports Biosciences. 2014: 7, 593-603. DOI:10.30486/epp.2023.1973090.1008
6-Kraemer RR, Castracane VD. Exercise and humoral mediators of peripheral energy balance: ghrelin and adiponectin. Exp Biol Med 2007;232:184-94. PMID: 17259325
7-Kraemer RR, Chu H, Castracane VD. Leptin and exercise. Experimental Biology and Medicine. 2002;227(9):701-8. DOI: 10.1177/153537020222700903
8-Moradi Fattah, Amini Aghdam Soran, Abdi Jamal, Mateen Homai Hassan. The effect of strength training on serum levels of adiponectin, testosterone and cortisol in sedentary lean men. Scientific Journal of Birjand University of Medical Sciences, 2012:20(2): 125-135.DOI: 10.30486/epp.2023.1973090.1008
9-Michael P. Scheid & Gary Sweeney. The role of adiponectin signaling in metabolic syndrome and cancer. Rev Endocr Metab Disord. 2014: 15:157–167. DOI: 10.1007/s11154-013-9265-5
10-Mogharnasi M, Gaeini AA, Sheikholeslami Vatani D. Comparing the Effects of Two Training Methods of Aerobic and Anaerobic on some Pre-inflammatory Cytokines in Adult Male Rats. Iranian Journal of Endocrinology & Metabolism. 2009; 11(2): 192-228. URL: http://ijem.sbmu.ac.ir/article-1-766-en.html
11-Samira Seifi & Mohammad Reza Tabandeh & Saed Nazifi & Mehdi Saeb & Sadegh Shirian & Parisa Sarkoohi. Regulation of adiponectin gene expression in adipose tissue by thyroid hormones. J Physiol Biochem. 2012: 68:193–203DOI: 10.1007/s13105-011-0131-1
12-Zeng Q, Isobe K, Fu L, Ohkoshi N, Ohmori H, Takekoshi K, et al. Effects of exercise on adiponectin and adiponectin receptor levels in rats. life Sci 2007;80:454-9. DOI: 10.1016/j.lfs.2006.09.031
13-Phillips A, Cobbold C. A Comparison of the effects of aerobic and intense exercise on the type2 diabetes mellitus risk marker adipokines, adiponectin and retinol binding protein-4. Int J Chron Dis, 2014: 8; 231-239. DOI: 10.1155/2014/358058
14-Mohibi, Hamid. Moqransi, Mehrzad. Rahmani Nia, Farhad et al. The effect of 12 weeks of changing life activities on gene expression and plasma concentration of adiponectin in obese men. Iranian Journal of Endocrine and Metabolism. 2022: 12; 25-33. http://ijem.sbmu.ac.ir/article-1-963-en.html
15-Jafari Ahmad, Ramezani Alireza. The effect of eight weeks of intermittent and resistance training and continuous and resistance training on strength, body composition and lipid profile in overweight non-athletic boys aged 14 to 17 years. Sports Biology Journal. 2011: 17; 5-22. https://doi.org/10.22059/jsb.2013.29775
