-
Open Access Article
1 - NMR and Solvent Effect Study on the Active Site of Oxidized Azurin
K. Shahanipour T. Nejad Salari F. Mollaamin M. Monajjemi -
Open Access Article
2 - Dielectric Constant and Solvent Effect Investigafion on Listeria monoeytogenes In1B-13- sheet Conformation: an Al. initio-NMR study
E. Shirkhodaee Tari M. Monajjemi -
Open Access Article
3 - اثر میدان های الکترومغناطیسی با فرکانس 50 هرتز روی غدد تناسلی و هورمون های جنسی موش نر نژاد NMRI
نفیسه پذیره وحیده سادات عباس نیا کیوان کرامتی بهمن دلالت داوود دورانیان -
Open Access Article
4 - Protection effect of Curcumin in ovary culture in NMRI mice
Mohsen Husseini farhad mohammadi gheshlagh Zahra khodaparast ali Mohammad einiUsing antioxidants is a known method to increase the number of follicles and ovulation in animals and humans. Curcumin inhibits lipoxygenase, cyclooxygenase. Hence in this study, we examine the effects of different concentrations of curcumin on ovarian tissue culture in MoreUsing antioxidants is a known method to increase the number of follicles and ovulation in animals and humans. Curcumin inhibits lipoxygenase, cyclooxygenase. Hence in this study, we examine the effects of different concentrations of curcumin on ovarian tissue culture in NMRI species mice. In this study, 40 varies of female mouse with five weeks ages are transferred to organ culture containers. Studied groups treated by different concentrations of curcumin (10, 20, 40, 80) ng/ml. The ovaries were cultured for 6 days and studied in the case of number of follicles and single layers size and granulosa and analyzed by SPSS software version 20 and ANOVA test. The number of single layer primary follicles in control group (2/3 ± 7/15) and treat groups with 10, 20, 40, 80 ng/ml concentrations of curcumin were (9/5 ± 3/33, 0/5 ± 0/31, 2/4 ± 5/31, 2/3 ± 7/15) respectively which showed a significant increase in all of the treat groups compared with control group (P <0.05). There is also a significant increase in the number of mature follicles in the number of mature follicles cultured in control group (0/4±40) compared with treat group with 10 ng/ml (2/3 ± 5/48). According to the obtained results on the number and quality of follicles, it seem that this method is effective in production, maintain and development of ovarian follicles in culture medium. Manuscript profile -
Open Access Article
5 - Effect of phytosterol and Bacillus coagulant probiotic in reducing blood cholesterol
Maryam Arjomandi far Bahareh Pakpour Rahebeh Amiri DehkharghaniTarget and background: In recent years, many studies have been conducted on high-risk factors for some blood lipids, which can lead to the development of cardiovascular diseases. The most important goal of this study is to investigate the effect of phytosterol and Bacil MoreTarget and background: In recent years, many studies have been conducted on high-risk factors for some blood lipids, which can lead to the development of cardiovascular diseases. The most important goal of this study is to investigate the effect of phytosterol and Bacillus coagulant probiotic on the reduction of blood cholesterol in adult rats. Material and Methods: 40 Male NMRI mice with a weight of 25-30g were used .The mouse were divided into 5 groups of 8, including: control group, HCD group (1% of the weight of the food consumed cholesterol diet), Experimental group 1 (daily, in addition to cholesterol diet, 0.1g of phytosterol Experimental group 2 (daily, in addition to cholesterol diet, 0.2g of Bacillus coagulant bacteria plus animal oil was gavaged), Experimental group 3 (daily, in addition to cholesterol diet, 0.1g combination of phytosterol and Bacillus coagulants probiotic were digested with germicidal oil). Sperry samples were taken from the blood samples at the end of the experiments, and cholesterol, triglycerides, HDL and LDL blood samples were measured and. Results: Cholesterol, triglyceride, HDL and LDL showed a significant decrease compared to the control group. Conclusion: According to the above results, it can be said that phytosterol and Bacillus coagulant probiotic simultaneously decrease blood lipids, and therefore, it is recommended to use this pump. Manuscript profile -
Open Access Article
6 - Solvent Effect on the Molecular Structure, Chemical Reactivity and Spectroscopy Properties of Z-Ligustilide: A Main Active Component of Multitude Umbelliferae Medicinal Plants
Mahmoud Osanloo Reza Ghiasi -
Open Access Article
7 - Synthesis and Characterization of New Schiff Bases of Ethylenediamine and Benzaldehyde Derivatives, Along with Their Iron Complexes
Rafeye Radfard Anita Abedi -
Open Access Article
8 - The comparision of NQR-NMR tensors and chemical reactivity of Mirtazapine and Normirtazapine analogues using quantum mechanics methods
Arezoo Tahan Mahya KhojandiThe density functional theory (DFT) methods were used to investigate and compare NMR-NQR tensors and chemical reactivity of mirtazapine and normirtazapine compounds. The obtained results in B3LYP/6-311++G** level of theory showed that the values of NMR chemical shieldin MoreThe density functional theory (DFT) methods were used to investigate and compare NMR-NQR tensors and chemical reactivity of mirtazapine and normirtazapine compounds. The obtained results in B3LYP/6-311++G** level of theory showed that the values of NMR chemical shielding and NQR tensors of nitrogen nuclei in the considered analogues are dependent on chemical media, molecular structure and resonance interactions. So that, nitrogen atoms with identical positions in two analogues revealed the almost same NQR tensors, and chemical shielding values around themselves. NBO analysis also represented that resonance energy value related to LP(1) N10→ 𝛔* or π* interactions is the most value among all resonance interactions in both considered structures. Based on NBO analysis and NMR-NQR results, it can be deduced that by increasing participation of lone pairs of nitrogen atoms in the ring resonance interactions and aromaticity development in normirtazapine structure, the values of NQR tensors were increased; while in mirtazapine structure, by increasing negative charge on nitrogen atoms, the values of NQR and NMR tensors around them were increased.The comparision of reactivity criteria of two investigated analogues using NBO analysis represented that the structural differences of two analogues didn’t have remarkable effects on their chemical reactivity. Manuscript profile -
Open Access Article
9 - New flavonoid glycoside from Vicia faba L.
A.E. Allam -
Open Access Article
10 - Phytochemical analysis of Echinops macrophyllus Boiss & Hausskn
Azadeh Khademian Mahdi Moridi Farimani Mostafa Alilou Mojtaba AsadollahiEchinops macrophyllus Boiss & Hausskn, also known as “Shekartighal kohgiluyeh” in Persian, is a prickly perennial herbaceous plant. Various species within the genus Echinops have traditionally been used as remedies for severe coughs, nervous attacks, and MoreEchinops macrophyllus Boiss & Hausskn, also known as “Shekartighal kohgiluyeh” in Persian, is a prickly perennial herbaceous plant. Various species within the genus Echinops have traditionally been used as remedies for severe coughs, nervous attacks, and infectious diseases. This study aimed to isolate and elucidate the structures of the compounds found in the aerial parts of E. macrophyllus. The ethyl acetate extract from the aerial parts of the plant was fractionated using column chromatography. The structures of the isolated compounds were characterized using 1H NMR, 13C NMR, 1H-1H COSY, HSQC-DEPT, HMBC and NOESY techniques. Phytochemical analysis of the plant resulted in the isolation of six compounds (1-6), including one triterpenoid (α-amyrin) (4), three sterols involving 3-O-[β-D-(6’-tetradecanoate)-glucopyranosyl]-β-sitosterol (6), β-sitosterol (3), and daucosterol (5) as well as two phenolic compounds, namely p-hydroxybenzoic acid (1) and ethyl-2-hydroxy-trans-cinamate (2), from this species for the first time. It is noteworthy that these compounds have previously been reported to exhibit various biological activities. Manuscript profile -
Open Access Article
11 - A review of 13C NMR spectra of drimane sesquiterpenes
Sylvia Awino Opiyo -
Open Access Article
12 - Study of Changes Kidney Tissue of White Albino NMRI Mice affected by the Gasoil
Nasim Naeimi Zohreh Fazlollahi Hamid reza Adeli Kobra Zare Nima MehrabiInroduction & ObjectiveGasoil is one of mostly-used oil products applied as diesel fuel, for instance, which, since it consists of aromatic compounds, is among the most important environmental pollutants. Considering its harmful effects on living organisms and human bei MoreInroduction & ObjectiveGasoil is one of mostly-used oil products applied as diesel fuel, for instance, which, since it consists of aromatic compounds, is among the most important environmental pollutants. Considering its harmful effects on living organisms and human beings, the purpose of the present study was to investigate the effects of gasoil ingestion on kidney factors of white Albino NMRI mice.Materials and Methods:40 adult mice, with an average weight of 28 grams, were placed in four groups. Adult male mice were placed in two groups including a control group and a treatment group and adult female mice were divided into two groups of control and treatment. For 14 days, the treatment groups were fed once per day with 0.2cc of pure gasoil solution with a ratio of 6.6 mg/kg of the mice’s weightAfter weighing, anesthesia and macroscopic and microscopic studies of through the slides prepared, the desired parameters measured using the software motik. Then, the analyses were performed using SPSS V:19 software.ResultsIn the male and female extreatmentgroupscompared to thecontrol group in Variations in kidney tissue,indicated a significantrelationship(Pthe outercortex(except theinnercortex) kidney(30%,40%), increased thickness of the internal and externalmedulla(20%,21%). Reduced diameter of the proximal (43%) and distal tubule(30%), increased diameter of collecting tubule(60%,30%).Conclusion: Due to the increased use of gasoil and generalization of the results of the present research to human kidney tissue damage, this substance imposes irrecoverable damages on human health. Hence, necessary measures should be taken by authorities for replacing, reducing its effects and raising public awareness of the methods of dealing with its effects. Manuscript profile -
Open Access Article
13 - Study Of Morpholineand Physiological Saline Effect on Blood Parameters and Spleen Tissue Of NMRI Albino Male Mice
Nasim Naiemi Hamid Reza Adeli Kobra ZareInroduction and Objective: Morpholine is a substance with various applications in industry and agriculture which toxic effects can be absorbed into the body by ingestion, by inhalation and through skin. The present study aimed to study of morpholineand physiological sa MoreInroduction and Objective: Morpholine is a substance with various applications in industry and agriculture which toxic effects can be absorbed into the body by ingestion, by inhalation and through skin. The present study aimed to study of morpholineand physiological saline effect on blood parameters and spleen tissue of6-week-old nmri albino male mice Materials and Methods: 40 adult male mice were placed in 4 experimental groups including control group, physiological saline (sham) group, treatment group A, fed with 300 mg/kg per day for 15 days, 1 ml of the prepared solution (0.009 ml morpholine+ 0.91 ml of distilled water) and group B, treated using the same method with the same volume of morpholine and physiological saline in the same period of time. After weighing, anesthesia and blood sampling, the number of red blood cells, hematocrit and hemoglobin were respectively measured using Neubauer slide, hematocrit capillary tube, and Sally method applying a plasma density refractometer. Microscopic and structural studies were conducted on prepared slides of spleen and statistical analyses were performed using SPSS19 software. Results: Increased number of red blood cells (%6.7), hematocrit (%21), plasma density (%25), and hemoglobin (%10) and decreased thickness of splenic capsule wall and becoming more fibrous (%8.3), increased thickness of central arteriole wall of white pulp (%30), increased spleen weight (%6.14), and reduced body weight (%2.14) were observed in group A, compared to control group and sham group. Considering group B, all listed features (except thickness of splenic capsule wall and weight loss) decreased. The results indicated a significant difference between group A and B (pConclusion: The significance of this relationship indicated that morpholine increased blood parameters, caused parenchyma adhesion, led to inflammation and increased spleen weight and decreased body weight and that physiological saline decreased its adverse effects. Given destructive effects of morpholine and its usage in our daily life, industry should look for a suitable replacement in order to maintain human health. Manuscript profile -
Open Access Article
14 - A Systematic Approach to Sensitivity Analysis of Fault Tolerant Systems in NMR Architecture
Kourosh Aslansefat Gholamreza Latif ShabgahiA fault tree illustrates the ways through which a system fails. It states different ways in which combination of faulty components result in an undesired event in the system. Being used in phases such as designing and exploiting industrial systems, and the designers abl MoreA fault tree illustrates the ways through which a system fails. It states different ways in which combination of faulty components result in an undesired event in the system. Being used in phases such as designing and exploiting industrial systems, and the designers able to evaluate the dependability attributes such as reliability, MTTF and sensitivity. In addition, in the mentioned ability, the fault tree is a systematic method for finding systems bottlenecks and weakness point. In spite of its extensive use in evaluating the reliability of systems, fault tree is rarely used in calculating sensitivity. In the last decade, few researches has been conducted in this field, however these methods are not applicable to large scale systems and are not systematic. This paper provides a systematic method for evaluating system sensitivity through fault tree. Then, it introduces sensitivity of NMR architecture as one of the common structures of fault tolerance which is used for enhancing systems’ reliability, safety and availability in industry. This article presents a comprehensive and parameterized formula for NMR structure's sensitivity. The presented method can be a great help for designing and exploiting reliable systems engineers in systematic and instant calculation of sensitivity by means of fault tree. Manuscript profile -
Open Access Article
15 - Synthesis of iminofurane derivatives using one pot multicomponent reaction: Dynamic NMR Study
Sayyed Jalal Shams-Najafi Maryam Ghazvini Faramarz Rostami-Charati -
Open Access Article
16 - Structure and isomeric studies of 1,3-diaryl-H-benzo[f]chromene, catalyst effect or thermodynamic stability? An ab initio study
Mohammad Vakili Hossein Eshghi Maesam Raeisian Raheleh Afzali Ali Reza Berenji Hadi Behzadi -
Open Access Article
17 - Investigation the effect of carboplatin on oogenesis and uterus changes in adult female NMRI mice strain
Sepideh Gholami Yarahmadi nasim HAYATI ROODBARI KAZEM PARIVAR Gholamhassan VaeziCancer is one of the most common diseases around the world. The most important therapies for cancer are chemotherapy that is performed by various medications. One of the common drugs in chemotherapy is “Carboplatin”. In this study, the effects of Carboplatin MoreCancer is one of the most common diseases around the world. The most important therapies for cancer are chemotherapy that is performed by various medications. One of the common drugs in chemotherapy is “Carboplatin”. In this study, the effects of Carboplatin on oogenesis and uterine changes in NMRI mouse strain have been investigated In vivo. In this study, 30 adult female mice were randomly divided into five groups: control, sham and three experimental groups. Experimental groups were injected Carboplatin with 0.36, 0.18, 0.09 mg/ml density for 28 days and all were injected subcutaneously. After describing the animals, the ovary and uterus were separated and subjected to histopathologic and stained by hematoxylin and eosin. Blood sampling was performed to study both estradiol and FSH. The results were analyzed using one-way ANOVA and SPSS software. By using Carboplatin,, the number of primordial, secondary, Graafian follicles, corpus lutea and blood vessels decreased and the number of atretic follicles increased. The diameter of ovary in experimental groups decreased, but there was no significant change in diameters of follicles. Uterine studies showed that, the uterine’ diameter and layers, and the diameter of lumen reduced. In addition, the number of uterine glands decreased. Also, the levels of FSH and estradiol decreased. Regarding to using Carboplatin, this drug by decrease in the number of primordial, secondary and Graafian follicles, increase in number of atretic follicles, and also disruption of the hormonal system, the probability of premature aging may increase and has a negative effect on fertility. Manuscript profile -
Open Access Article
18 - Synthesis and spectral characterization of naphthyldihydrazones derived from some 1,3- dicarbonyl compounds and their Ni(II), Cu(II) and Zn(II) complexes
Muhammed Ummathur Anjali Krishnan Perumpalli Ummer -
Open Access Article
19 - Metal complexes of unsaturated polycarbonyl compounds derived from benzoyl acetone and aromatic aldehydes
Muhammed Basheer Ummathur Anjali Krishnan Mathew Ukken -
Open Access Article
20 - Effects of Alcoholic Extract of Aerial Parts of Rue onMale Mice (NMRI) Organs of Reproduction
عبدالحسین شیروی شهلا روزبهانی سمانه حبیبیIntroduction The plants have close relation to the culture of humans . most of plants have recovery effects Ruta graveolens L. is the plant which was used for increasing period , abortion in women, rhomatysm In this study,the effects of the alcoholic extract of Rue MoreIntroduction The plants have close relation to the culture of humans . most of plants have recovery effects Ruta graveolens L. is the plant which was used for increasing period , abortion in women, rhomatysm In this study,the effects of the alcoholic extract of Rue are experimentally examined on the reproductive organ of male mice. Method In this study which is functional and fundamental uses small mice NMRI. The weight of testicles , epididym, vaso deferan and the volume of testicles and the number of sperm was identified. Results Comparing testiclesand#39; weight, epididym,deferan, show a significant decrease (pandlt; .05) in 350 and 450 of doses in control and experimental groups. . Size of the testis and number of sperms show a significant decrease (pandlt; .05) in experimental groups, sham and control. Conclusion The results have shown alcoholic extract RG Can effect on activity in organs of male generation . and probably can be used to control reproduction. Manuscript profile -
Open Access Article
21 - Effects of Juniperuse sabina on Uterine Changes of Adult NMRI Mouse in vivo
S. Mortazavi Gazar N. Hayati Roodbari F. Tafvizi P. YaghmaeePhytotherapy is an ancient knowledge and people have been using herbs for centuries to heal themselves.Different researches have indicated that due to the side effects of synthetic drugs people nowadays have a tendency to use herbal medicines to treat their diseases.A f MorePhytotherapy is an ancient knowledge and people have been using herbs for centuries to heal themselves.Different researches have indicated that due to the side effects of synthetic drugs people nowadays have a tendency to use herbal medicines to treat their diseases.A few number of these researches have been dedicated to studying the effect of herbal medicines research. NMRI adult female mice which weighed30 to35 grams were divided into 5groups in this study.The groups included one control group, a sham group and 1, 2, and 3 experimental groups.The control group used the special water and food for mice which was fed to all the groups.The 1, 2 and 3 experimental groups received 135, 45, and 15 milligrams per kilogram of their body weight doses of the essence of Juniperus sabina respectively for a period of 30 days. The results indicate that the essence of this herb increases the weight of the uterus.All three layers showed increase thickness of diameter and the number of the blood vessels of the uterus decreased in the experimental groups 1 and 3.The number of the follicles which had undergone atrophy and the yellow-bodies (corpus luteum) increased significantly but the primordial and primary follicles decreased in number.These results suggest that this herb is harmful to pregnant women and it must be consumed under the supervision of a physician if necessary.The manner in which this herb effects the oogenesis hormones and the extraction of the effective substance and applying it on the uterus and the ovaries must be examined. Manuscript profile -
Open Access Article
22 - Physiological and Histological Studies of Obesity Inducing a High Fat – Diet in Adult NMRI Strain Mice
فرناز بناکار کاظم پریور پریچهر یغمایی هما محسنی کوچصفهانیObesity is a major health concern worldwide against which development of new strategies is warranted. Animal models are a valuable tool in these studies and could be developed using a simple and cost effective diet in susceptible strains. Adult NMRI mice weighing 25andp MoreObesity is a major health concern worldwide against which development of new strategies is warranted. Animal models are a valuable tool in these studies and could be developed using a simple and cost effective diet in susceptible strains. Adult NMRI mice weighing 25andplusmn;4 g were fed by a high fat diet for six weeks (E group) in comparison with a control group(C) receiving standard chow. Weekly measurements of body weight were performed. Animals were sacrificed after six weeks, and abdominal fat amount, fat liver accumulation, and LDL-C, HDL-C, cholesterol and triglyceride were measured. Histological studies were done on kidney, liver and testis. Body weight of E group increased up to about 50% (1.25-fold more than C group), their abdominal fat amount showed a two-fold increase compared with the C group(pandlt;0.001), and morphologic differences were observed in liver tissue relative to fat accumulation. Of biochemical factors, only triglyceride levels showed statistically significant increase in the E group (pandlt;0.05). Microscopic assessment of kidney, liver and testis samples, regarding to cells size and number showed no significant differences between C and E groups. This method is proposed as a mean to simulate an early stage of obesity. Manuscript profile -
Open Access Article
23 - The Effects of Vitex Agnus Castus and Foeniculum volgare Alcholic Extract on HPG Axis and Spermatogenesis of NMRI Mice
راحله فاضلی عبدالحسین شیرویVitex agnus castusand Foeniculum volgare are phytoestrogeic herbs native to the Middle East and southern Europe. They have clinical usage in so many countries. In this research, the effects of Vitex agnus castus fruit extract and Foeniculum volgare seed extract were inv MoreVitex agnus castusand Foeniculum volgare are phytoestrogeic herbs native to the Middle East and southern Europe. They have clinical usage in so many countries. In this research, the effects of Vitex agnus castus fruit extract and Foeniculum volgare seed extract were investigated on spermatogenesis and Testosterone, LH and FSH Hormon of male NMRI mice.This is an experimental study in which adult male mice were chosen and divided into 3 groups: control, vehicle, and experimental. Animals were daily injected (i.p.) with 100 , 200 mg/kg of Foeniculum volgare seed extract and 200 , 300 mg/kg of Vitex agnus castus and synthetic dos of Vitex agnus castus (300) + Foeniculum volgare (200) for 15 consecutive days. Then the animals were weighed and eventually killed. 2 weeks after the last injection.Testosterone and LH, FSH serum hormone of animal was assayed .The caudal part of the epididymis was used for sperm counting. After macroscopic investigation (weight, diameter and volume of Testes and weight of epididymis) tissues were fixed in Buinand#39;s fixative. Tissues were cut at 5 andmu;m, stained with Hematoxylin and Eosin (Handamp; E).Collected data was analyzed by the SPSS software by using one-way ANOVA. No significant differences in volume, weight and diameter of testes and weight of epididymis was seen. Significant reduction in LH, FSH and Testosterone hormon in all of experimental group was seen. Light microscopic studies showed a significant reductionin in number of germinal cells and several holes that were found scattered in the tubules and Testis also showed a general disarrangement in various germinal elements of seminiferous tubules in doses of 200 , 300 vitex agnus castus and synthetic dose. Result of sperms count indicated a significant decreasing of spermatozoa in all of experimental groups. Vitex agnus castus and Foeniculum volgare contains essential oils, iridoid, glycosides, flavonoids diterpenes, and essential fatty acids. The results suggest that its contraceptive effects is related to its flavonoids and essential fatty acids but further studies is needed to focus on the pharmacokinetics of this plants. Manuscript profile -
Open Access Article
24 - Protective Effect of Magnesium Sulfate against Experimental Models of Gastric Ulcer in NMRI Mice
Roya Rostami Akram Eidi Pejman Mortazavi Shahrebano OryanGastric ulcers are common digestive disorders involving stomach mucosal lesions with worldwide prevalence. There are different reasons for peptic ulcers. One common reason among west societies is ethanol consumption. The aim of the present study is pretreatment by magne MoreGastric ulcers are common digestive disorders involving stomach mucosal lesions with worldwide prevalence. There are different reasons for peptic ulcers. One common reason among west societies is ethanol consumption. The aim of the present study is pretreatment by magnesium sulfate. In this study 66 male NMRI mice were randomly divided into 11 groups and the administered mice were followed up daily for 15 days. These groups include control group (intact), control ulcer group (ethanol 10 mg/kg), standard group (omeprazole 40 mg/kg and ethanol), experimental groups (magnesium sulfate 50, 100, 200, 300 mg/kg), and experimental ulcer groups (magnesium sulfate 50, 100, 200, 300 mg/kg and ethanol). At the end of the relevant period, the levels of oxidative stress parameters were biochemically evaluated. The results of this study revealed that the activity of catalase, glutathione peroxidase and superoxide dismutase in control ulcer group significantly decreased compared to the control group. Oral administration of magnesium sulfate produced no significant effect on catalase, glutathione peroxidase and superoxide dismutase activities in intact animals. Animals in experimental ulcer groups represented a great increase in catalase, glutathione peroxidase, and superoxide dismutase levels over the treatment by magnesium sulfate. Moreover, our results showed that the amount of malondialdehyde in control ulcer group was significantly increased compared to the control group. Pre-treatment with magnesium sulfate caused no significant change on the amount of malondialdehyde in control group, while the level of malondialdehyde was considerably decreased in experimental ulcer groups. Furthermore, our results demonstrated that a pretreatment with MgSO4 could notably reduce oxidative stress and gastric lesions. Manuscript profile -
Open Access Article
25 - Protective Effect of Royal Jelly on Methotrexate Infertility in Female Rats
Atikeh Amindoost Mona Farhadi Parvin Torabzadeh -
Open Access Article
26 - The Effect of Red Ginseng Water Extract on Oogenesis and Uterus Tissue of Adult NMR Mice
Z. Zohrevand Asl N. hayati roudbari S. Mohamadi Gorji K. ParivarHerbal product consumption and use of herbal medicines are now the most popular treatment methods. In the meantime, ginseng belongs to the genus Panax of the family Araliaceae has been among top ten common plants in people's food basket. The objective of this study was MoreHerbal product consumption and use of herbal medicines are now the most popular treatment methods. In the meantime, ginseng belongs to the genus Panax of the family Araliaceae has been among top ten common plants in people's food basket. The objective of this study was to evaluate the effect of ginseng extract on oogenesis in the adult NMRI strain. In this experimental study, we randomly divided 30 adult female mouse NMRI strain into 5 groups for 30 d as follows: 1) Control (not gavaged), 2) Sham (gavaged water), 3) Treatment groups (gavaged 100 mg/kg, 200 mg/kg and 300 mg/kg ginseng extract). Ginseng water extract was prepared in distilled water. After 30 d, they were killed. Ovarian and uterine tissue were removed and studied.The number of primary follicles in three experimental groups was 100, 200 and 300 mg/kg. Secondary follicles with doses of 100 and 200 mg/kg groups and graaf follicle with dose of 200 mg/kg group showed significant increase. Reduction in atretic follicle in groups with doses of 100 and 300 mg/kg was observed. Uterine studies showed significant increase in the thickness of perimeter and endometrial layer in group with dose of 100 mg/kg and the number of glands in experimental groups 1 and 2 showed increased.Finally, wecan say that using red ginseng water extract is effective on oogenesis and uterus tissue. Manuscript profile -
Open Access Article
27 - Exploration of the Physical and Mechanical Properties of Thianthrene Nanostructures by Using Scigress
Hassan Ghalami Bavil Olyaee Husam Jawad Oraibi AltaieThianthrene and its derivatives have attracted considerable attention in the realm of organic semiconductors owing to their intriguing electronic and optical properties. This paper offers a comprehensive examination of Thianthrene, concentrating on its principal feature MoreThianthrene and its derivatives have attracted considerable attention in the realm of organic semiconductors owing to their intriguing electronic and optical properties. This paper offers a comprehensive examination of Thianthrene, concentrating on its principal features, including its highest occupied molecular orbital (HOMO) at -8.03 eV, lowest unoccupied molecular orbital (LUMO) at -0.46 eV, ultraviolet (UV) absorption spectrum, and infrared (IR) spectroscopy data. The inquiry, utilizing data derived from Scigress, unveils crucial insights into the electronic structure and spectroscopic traits of Thianthrene and its derivatives. The UV absorption spectrum at 160 nm provides glimpses into the optical attributes and potential applications in optoelectronic devices like OLEDs. Moreover, the IR spectroscopy data illuminates the molecular vibrations and structural attributes of Thianthrene, facilitating the understanding of its chemical reactivity and potential strategies for functionalization. Overall, the results underscore Thianthrene's significance as a promising contender for organic semiconductor materials and highlight avenues for further exploration and development in this domain. Additionally, the ultimate heat of formation of Thianthrene is computed using computational modeling techniques offered by Scigress, yielding a value of 56.4736 kcal/mol. This calculated heat of formation furnishes critical thermodynamic data, contributing to a more profound understanding of Thianthrene's stability and reactivity in various chemical environments. Manuscript profile -
Open Access Article
28 - Spectroscopic study of diphenyl [(S)-(–)-1-phenylpropanamido]-phosphate: differences of diastereotopic groups
Farnaz Eslami Mehrdad Pourayoubi Fahimeh Sabbaghi Sahar BaniyaghoobAbstract The synthesis and crystal structure of diphenyl [(S)-(–)-1-phenylpropanamido]-phosphate, (C6H5O)2P(O)[NH-(S)-(–)CH(C2H5)(C6H5)], was previously reported. Here, the spectroscopic features (1H-NMR, 13C{1H}-NMR, 31P{1H}-NMR and IR) are investigated. In the 1H-NMR MoreAbstract The synthesis and crystal structure of diphenyl [(S)-(–)-1-phenylpropanamido]-phosphate, (C6H5O)2P(O)[NH-(S)-(–)CH(C2H5)(C6H5)], was previously reported. Here, the spectroscopic features (1H-NMR, 13C{1H}-NMR, 31P{1H}-NMR and IR) are investigated. In the 1H-NMR and 13C{1H}-NMR spectra, the diastereotopic C6H5O groups show two sets of signals. Typically, in the 13C{1H}-NMR spectrum, the doublets at 151.08/151.20 ppm and 120.52/120.55 ppm, with 2JCP = 6.5/6.6 Hz for the first pair and 3JCP = 4.9/4.7 Hz for the second pair are associated to the diastereotopic ipso-C atoms and diastereotopic ortho-C atoms. In the 1H-NMR spectrum, the signals related to diastereotopic phenyl groups overlap with those of phenyl group of chiral amine. The ipso-carbon atom of chiral amine fragment appears a doublet signal at 144.85 ppm (3JCP = 2.7 Hz). The phosphorus signal (31P{1H}-NMR) appears at –0.49 ppm. in this work NMR and spectroscopic main part are going to be consider and proved because of the chiral importance in drug delivery. Keywords: Amidophosphodiester; IR; NMR; Phosphorus-carbon coupling constant Manuscript profile
Sanad
Sanad is a platform for managing Azad University publications
Links
Related Centers
Technical Support
Official pages
The rights to this website are owned by the Raimag Press Management System.
Copyright © 2021-2024