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        1 - The effect of endurance training with royal jelly consumption on dopamine in the hippocampus tissue of rats with Alzheimer's disease
        Fakhradin Hassanlouei Seyed Ali Hoseini Laleh Behbudi Tabrizi Masod Haji Rasouli
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        2 - The EffectOf an Endurance Training Period on Plasma Alanine Aminotransferase Level in Patients with Nonalcoholic Fatty LiverDisease
        Elham Karami Mehdi Reza Gholi Zadeh Hasan Ahanghar Khalil Mahmoodi
        Inroduction and Objective: The purpose of current research is to study effect of a selected endurance training period on alanineaminotransferase (ALT) of plasma in patients with nonalcoholic fatty liverdisease (NAFLD).Materials and Methods: So 20 subjects (10 males and More
        Inroduction and Objective: The purpose of current research is to study effect of a selected endurance training period on alanineaminotransferase (ALT) of plasma in patients with nonalcoholic fatty liverdisease (NAFLD).Materials and Methods: So 20 subjects (10 males and 10 females) were grouped randomly to 10 people experimental group and 10 people control group. The experimental subjects participated in 12 week endurance training (3 day a week, each session 45 minute and at 60% maximal heart rate) despite of control group. Blood sampling was done before and after 12 week period in order to measure plasma ALT using the colorimetric method. Data were analyzed using dependent and independent paired t-tests at  significance level.Results: The results of research demonstrated that endurance training period cause significant reduction on ALT of plasma in experimental group, while that wasn't changed in control group.Conclusion:It was concluded that we can utilize to perform endurance training to reduce ALT of plasma in NAFLD and improve them. Manuscript profile
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        3 - Effect of endurance, resistance and combined trainings on glycemic control and lipid profile of type2 diabetic patients
        Farzad Khosravi Zahra Rahimi
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        4 - Cardio metabolic adaptation to exercise: a review article
        Nahid Mohammadi javid Mehran Ghahramani
        Abstract  Aim:  The aim of this study was to investigate the Cardio metabolic adaptation to exercise. Methods: In this research, cardiac muscle metabolism, myocardial energy production, myocardial energy storage and myocardial energy use, cardiac metabolism More
        Abstract  Aim:  The aim of this study was to investigate the Cardio metabolic adaptation to exercise. Methods: In this research, cardiac muscle metabolism, myocardial energy production, myocardial energy storage and myocardial energy use, cardiac metabolism in ischemia and arrhythmia, the role of AMPK enzyme in cardiac energy metabolism and its different forms of AMPK during reperfusion, the role of AMPK during reperfusion, adaptation of cardiac metabolism  to chronic hypoxia, the role of mitochondrial calcium in myocardial metabolism and finally the effect of endurance training and cardiac metabolism were investigated. Results:    The finding showed that the myocardium has the ability produce energy from several substrates including: it contains fatty acids, glucose, lactate, pyruvate, ketone bodies and some amino acids. The use of substrates specifically depends on the concentration of these substances in cardiac muscle cells and blood. Conclusion:    It can be concluded that cardiac muscle metabolism is affected by exercise and endurance training has a positive effect on myocardial metabolism.   Manuscript profile
      • Open Access Article

        5 - Comparison of the effect of resistance, endurance and concurrent exercises on adiponectin gene expression in hand and foot muscle tissues of male Wistar rats
        zahra malekian Tahereh Bagherpoor Nematollah Nemati
        Background & Aim: Adiponectin is a type of adipokine that is involved in sugar and lipid metabolism, this adipokine is in addition to the tissue that it is like and can become. The present study was designed to compare the effect of endurance, resistance and combined ex More
        Background & Aim: Adiponectin is a type of adipokine that is involved in sugar and lipid metabolism, this adipokine is in addition to the tissue that it is like and can become. The present study was designed to compare the effect of endurance, resistance and combined exercises on the level of adiponectin gene expression in the hand and leg muscles of Wistar rats. Materials & methods: The current study is an experimental research in which 40 healthy male Wistar rats were divided into four ten groups of control, resistance training, endurance and combined. Each group did their own exercises for 8 weeks. Finally, hand and foot muscles were examined to measure the adiponectin gene. Results: The results of the analyzes showed that the level of adiponectin gene expression was different among all groups (P < 0.001). The relative expression of adiponectin gene in all training groups increased significantly compared to the control group (P < 0.001).Also, comparing exercise groups together, combined exercises had the greatest effect and resistance exercise had the least effect. In intra-group comparison, adiponectin gene expression was higher in hand muscle than leg muscle during resistance training (P = 0.047), but gene expression was higher in leg muscle during endurance training (P = 0.029). These two muscles were not significantly different during combined training (P = 0.086). Conclusion: According to the results of this study, all types of sports training can increase the expression of adiponectin gene, but combined, endurance and resistance training have the greatest effect, respectively. Manuscript profile
      • Open Access Article

        6 - The effect of eight weeks of endurance training on some blood coagulation indices in elderly male Wistar rats.
        Mahdi Rahimi mostafa teymuri kharvi
        Background and Objective: An important part of cases related to sudden death and heart attack in the elderly can be attributed to obstruction of cerebral and coronary arteries due to thrombosis due to increased platelet count and activity. Therefore, the present study a More
        Background and Objective: An important part of cases related to sudden death and heart attack in the elderly can be attributed to obstruction of cerebral and coronary arteries due to thrombosis due to increased platelet count and activity. Therefore, the present study aimed to investigate the effect of eight weeks of endurance training on some blood coagulation indices were designed in elderly male Wistar rats.Materials and Methods: This study was conducted as a post-test with two groups (endurance training and control). In this study, we tried to control all research variables. These variables include the same food and water, the same storage temperature and humidity (23&plusmn;2 &deg; C and relative humidity of /055&plusmn;5), the same sleep and light cycle (12:12), the same gender and health status), all male and female The main training program included running on a treadmill with increasing duration and following the principle of overload from 25 minutes to 54 minutes and changing the training speed from 15 to 20 meters per minute. This program lasted for 8 minutes. 5 sessions per week were performed per week, to warm up the animals at the beginning of each training session for 3 minutes at a speed of 7 meters per minute and then to reach the desired speed per minute, 2 meters per minute was added to the treadmill speed To cool the body at the end of each session, the speed was reduced inversely to reach the initial speed. Manuscript profile
      • Open Access Article

        7 - Effect of endurance exercise preconditioning on TrkB levels and some behavioral functions of male rats Cause a stroke
        Meysam Fahim mostafa teymuri kharvi
        AbstractBackground and Objective: A valuable approach to increasing health and reducing brain damage is to use exercise and physical training as a pre-preparation that leads to some molecular cellular changes and improved behavioral functions.Materials and Methods: In t More
        AbstractBackground and Objective: A valuable approach to increasing health and reducing brain damage is to use exercise and physical training as a pre-preparation that leads to some molecular cellular changes and improved behavioral functions.Materials and Methods: In this quasi-experimental study, animals were randomly divided into three equal groups of 01, including endurance training, stroke and control. The training protocol in the endurance group included swimming in water for three weeks and five days a week for 01 minutes every day at a water temperature of 03 &plusmn; 3 &deg; C. Rats in the control group and the stroke group spent three weeks without any training. To create the ischemia model, the common carotid artery (CCA) was blocked for 01 minutes with aneurysm clamps. 32hours after ischemia, TrkB enzyme levels were assessed using Real Time Pcr and behavioral functions.Results: There was a significant difference in the TrkB variable between the endurance group and the stroke and control groups in favor of the endurance group (P = 10110). Also, a significant difference was found between the stroke group and the control group (P = 10110).In relation to neurological disorder, a significant difference was observed between the endurance group and the two groups of stroke and control (P = 10110).Conclusion: Aerobic exercise can produce positive neuroprotective effects in relation to neurogenesis by altering TrkB gene expression, which can also be seen in behavioral functions. Manuscript profile
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        8 - The effect of endurance and resistance training on the expression of myostatin and follistatin genes in the biceps muscle of aged male rats.
        Mahtab Moazzami Nasrin Nobahari
        Background and purpose: Aging is a natural process in human life. Sarcopenia is a gradual decrease in muscle mass and function that occurs with age. Materials and methods: In the present study, 30 male Wistar rats at the age of 18 weeks were randomly divided into thre More
        Background and purpose: Aging is a natural process in human life. Sarcopenia is a gradual decrease in muscle mass and function that occurs with age. Materials and methods: In the present study, 30 male Wistar rats at the age of 18 weeks were randomly divided into three groups, endurance training, resistance training and control (each group contains 10 rats). became Then, endurance and strength training groups participated in their own training for 8 weeks and 5 sessions per week. Results: The results of analysis of variance showed that there is a significant difference between the values of myostatin gene and follistatin gene in endurance, resistance and control groups. Also, the results of Tukey&#039;s post hoc test showed that endurance and resistance exercises had a significant effect on reducing myostatin gene expression. Also, the results of this test showed the increase of folstatin gene in both endurance and resistance groups compared to the control group. Conclusion: The results of statistical tests showed a significant decrease in the expression of the myostatin gene and a significant increase in the expression of the follistatin gene in the endurance and strength training groups compared to the control group. Finally, the findings of this study showed that strength and endurance training can change the expression of genes involved in hypertrophy of the quadriceps muscle of aged male rats. And it seems that these types of exercises can be useful to reduce the complications of sarcopenia caused by aging. Manuscript profile
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        9 - The Effect of 8 Weeks of Endurance Exercise, Consumption of Vanadium and Stevia on Structural Changes in the Hamstring Muscle of Type 1 Diabetic Rats
        Atefeh Sarhadi Ali Hassani Maliheh Ardakanizadeh
        Loss of muscle mass is one of the side effects of diabetes that may be delayed by regulating blood sugar levels through exercise or herbal supplements. Thirty-five male rats (180&plusmn;10 g) were assigned to seven groups of control, diabetic, diabetic + exercise, diabe More
        Loss of muscle mass is one of the side effects of diabetes that may be delayed by regulating blood sugar levels through exercise or herbal supplements. Thirty-five male rats (180&plusmn;10 g) were assigned to seven groups of control, diabetic, diabetic + exercise, diabetic + vanadium, diabetic + exercise + vanadium, diabetic + stevia, and diabetic + exercise + stevia. To induce type 1 diabetes, streptozotocin (55 mg/kg) was injected intraperitoneally, and vanadium extract (1mg/ml) was daily dissolved in water. The endurance training program consisted of eight weeks of treadmill running, five days a week, starting at 15 minutes at 20 meters/minute and ending at 35 minutes at 30 meters/minute in the final week. Histopathological changes in brain tissue were examined using a light microscope. In order to normalize the parametric data, Kolmogorov-Smirnov test and for their analysis, one-way ANOVA with Bonferroni post hoc test, and for non-parametric data, Kruskal-Wallis test (p &le; 0.05) were used. Body weight values ​​in all six experimental groups significantly decreased compared to healthy control group (p=0.001), in vanadium group compared to vanadium + exercise (p = 0.01), and in stevia + exercise group compared to stevia (p = 0.04). In the diabetic group, slight changes in cell number and size improved with exercise along with vanadium and stevia, and consumption of stevia, as well as cell degeneration with exercise along with vanadium and stevia, and consumption of vanadium and stevia (p=0.001). Eight weeks of endurance exercise, stevia, and vanadium intake appear to be effective in regulating body weight as well as improving the hamstring muscle damage caused by diabetes. . Manuscript profile
      • Open Access Article

        10 - Effect of Exercise at Morning in Comparison with Evening on Response of Spexin and Leptin to Eight Weeks of Endurance Training in Obese Women
        Mohammad Karimi Mozhgan Baghaei-Barzabadi
        Disturbance in regulation of energy balance in obesity involves several mechanisms, many of which are still not well understood. Circadian rhythms are followed by hormonal fluctuations, especially hormones involved in appetite. The aim of this research was to study the More
        Disturbance in regulation of energy balance in obesity involves several mechanisms, many of which are still not well understood. Circadian rhythms are followed by hormonal fluctuations, especially hormones involved in appetite. The aim of this research was to study the effect of eight weeks of endurance training in the morning compared to the evening on the levels of spexin and leptin in obese women. In this semi-experimental study, 30 obese female volunteers with an average age of 35.3 &plusmn; 4.4 years and a body mass index of 31.7 &plusmn; 1.2 kg/m2 were randomly divided into three equal groups (n = 10) including; Control, morning training and evening training groups. The protocol of endurance training was carried out for eight weeks, three sessions per week and with an intensity of 60 to 75% of the maximum heart rate. 48 hours before and after the intervention of endurance training, blood sampling was done under conditions of 10 hours of overnight fasting. Spexin and leptin values were evaluated by ELISA method. Data were analyzed by using one-way analysis of variance test at a significance level of p&lt;0.05. The results showed that exercise intervention in the morning and evening led to a significant decrease in leptin values (p=0.02) and a significant increase in spexin values (p=0.03). In comparison between morning and evening training, changes in leptin (p=0.01) and spexin (p=0.01) were higher in the evening session. Based on the findings of this study, it seems that endurance training with moderate intensity in a period of eight-week may have positive effects on the hormones of spexin and leptin in the matter of appetite. Evening training has better effects than morning training. Manuscript profile
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        11 - Comparison of the Effect of Eight Weeks of Endurance Training at Morning and Evening on Asprosin, Leptin, Insulin Resistance and Appetite Index in Non-athlete Obese Men
        bahman Zadeh-Hendijani sedigheh Hoseinpour Delavar mohammad karimi mehran ghahramani
        Satiety-hunger signals regulate rhythmic clocks in peripheral tissues through the availability of many macronutrients in the circulation. The aim of this research was to study the effect of eight weeks of endurance training in the morning and the evening on serum levels More
        Satiety-hunger signals regulate rhythmic clocks in peripheral tissues through the availability of many macronutrients in the circulation. The aim of this research was to study the effect of eight weeks of endurance training in the morning and the evening on serum levels of asprosin, leptin, insulin, insulin resistance and appetite index in non-athlete obese men. In this semi-experimental study, 36 non-athletic obese young men with an average age of 25.4 ± 3.3 years, weight 98.3 ± 7.7 kg, and body mass index 31.8±1.2 kg/m2 were selected as subjects in a targeted and available manner. Subjects were randomly divided into three equal groups including; Control, morning training and evening training. The endurance training protocol was implemented for eight weeks, three sessions per week and with an intensity of 60 to 75% of the maximum heart rate. Before and after the training period, blood sampling was done at 10 hours of overnight fasting state. The data were analyzed using one-way analysis of variance and at a significance level of p < 0.05. Eight weeks of endurance training led to a significant decrease in asprosin (p = 0.0001), leptin (p = 0.02), insulin (p = 0.0001), glucose (p = 0.0001), insulin resistance (p = 0.0001) and appetite index (p = 0.001). Tukey’s post hoc test indicated that, compared to the control group, evening training has a greater and more significant effect on all the mentioned variables. It seems that endurance training in morning and evening can have positive effects on asprosin, leptin, insulin resistance and appetite index. However, training in the evening seems to have more positive effects on these factors. Manuscript profile
      • Open Access Article

        12 - Valine Consumption And Endurance Exercise Modified The Inflammation In Rat Model Of Anxiety/Depression.
        Mohammad-Hossein Beigi