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      • Open Access Article

        1 - Investigation of Soliton phenomena for laser transfer in optical fibers and its application in tissue treatment
        zahra mahmoodzadeh zarandi parviz zobdeh
        Abstract:Human skin has three-layer non-homogeneous tissue. The thermal and physical properties of each layer including Epidermis, dermis, and hypodermis are different from each other. In treatment procedures, laser source intensity is adjusted based on thermal amount w More
        Abstract:Human skin has three-layer non-homogeneous tissue. The thermal and physical properties of each layer including Epidermis, dermis, and hypodermis are different from each other. In treatment procedures, laser source intensity is adjusted based on thermal amount which produced in each skin layer; furthermore, intensity control, optimization, and prediction of pulse shape before the interaction with tissue, is very important. Since, during the Laser-tissue irradiation, tissue temperature increases, and so uncontrollable temperature enhancement causes thermal harm on tissue.In this research, the Solitons general equation was considered. In order to having a predefined Gaussian shape of output laser pulse at the end of the transfer medium (optical fiber), numerical calculation was used. Solitons coefficients equation, include the dispersive coefficient, propagation constant, and coefficient of normalized loss has been obtained. The results could be used in determination of laser transfer medium structure, such as kind of material, coefficient of refractive, diameter and longitude length and etc. Recognition of fiber medium helps designers to provide a medium in order to establish Soliton, which input pulses are gained as output at the end of the fiber without any changes in shape. Access to different internal human organs could be possible by flexibility of optical fibers, as an important advantage. It seems, optimum parts determination of transfer medium may provide new horizon in controlled laser therapy. Manuscript profile
      • Open Access Article

        2 - nvestigation of the electron energy span spectrum on absorbed dose in tissue
        parviz zobdeh Mehdi Solaymani
        Electron-therapy is a therapeutic method for brain tumors that in this method, absorption dose has a high energy dependency. The purpose of this study is to determine the dependency of energy doses. To do this, first of all, by using the MCNP code, a simple whole phanto More
        Electron-therapy is a therapeutic method for brain tumors that in this method, absorption dose has a high energy dependency. The purpose of this study is to determine the dependency of energy doses. To do this, first of all, by using the MCNP code, a simple whole phantom has simulated according to existing standards , here the phantom has called MAS. Here we consider two textures for Phantom MAS, a bone structure and a soft texture made of water.Then we have designed an electron source as a beam or a disk that is located at a distance of 5 cm from the patient’s head with an energy of 10MeV, at a distance of 50 cm, so we have examined the absorbed dose and healthy texture and then we have changed the energy of the spring to 5 MeV and have examined it again.The nonlinear logarithmic diagram, indicates that less energy is absorbed in lower energy (5 MeV), of course this also depends on the size and location of the tumor, but the positive point is that the texture or structure still remains more healthy, in other words In electron beam with (5 MeV) of energy, the healthy texture is damaged less than (10 MeV) of energy. Also, the linear diagram indicates that the surface tumor with (5 MeV) of energy is cured better. Manuscript profile
      • Open Access Article

        3 - Electron guiding beam inside the tissue for treatment by using CARBON nanotube
        محبوبه باقری parviz zobdeh
        Today, electron therapy has a lot of advantages such as: its homogenous, dose in the target volume, low absorbed dose for the normal tissues, non-effective transmitted dose of air bubble which surrounded the target (in comparison of photon treatments), controllability i More
        Today, electron therapy has a lot of advantages such as: its homogenous, dose in the target volume, low absorbed dose for the normal tissues, non-effective transmitted dose of air bubble which surrounded the target (in comparison of photon treatments), controllability in turning on and electron beam flux adjustment during the treatment. It has no interchangeable case in the most treatment centers. Electron can use for up to 20cm depth in radiation therapies. In this study, we demonstrate, for the first time, a design of flexible guider for the electron accelerator output, which may increase the treatment ability effectively. One of the important of its advantages is non-limited ability in treatment of tumors in case of deep depth, in other words overcome to limitation of surface cancer treatment and providing a safe condition for other normal tissues during the radiation therapy. One of the important of its advantages is non-limited ability in treatment of tumors in case of deep depth, in other words overcome to limitation of surface cancer treatment and providing a safe condition for other normal tissues during the radiation therapy. in other words overcome to limitation of surface cancer treatment and providing a safe condition for other normal tissues during the radiation therapy. Manuscript profile
      • Open Access Article

        4 - Design and Manufacture of Automatic Vial Filling Machine and Radiopharmaceutical transmission at Hot Lab Imaging Center
        Milad Mohamadi Parviz Zobdeh
        Introduction:The purposes of design and Manufacturing of this device are providing an automation prototype system for radiopharmaceuticals preparing and transferring, increasing the safety and staff radiation protection, increasing the work accuracy, using the most stan More
        Introduction:The purposes of design and Manufacturing of this device are providing an automation prototype system for radiopharmaceuticals preparing and transferring, increasing the safety and staff radiation protection, increasing the work accuracy, using the most standard parts, reducing the number of parts and providing the design principles of production and assembly. Material and methods: Library research method and technical experiments were used to collect information. The proposed design is a theoretical-practical plan, and according to the existing systems of radiopharmaceutical generators is presented, this design was evaluated theoretically by providing the technical drawings at the first, then its mechanical sections were designed and the prototype was made. Results: According to direct relationship between low-dose radiation over long periods and the possible effects of radiation, especially cancer, and also the current trend of using radiopharmaceuticals in medical centers may increase the risks of radiation, the findings show that the use of this system in imaging centers will significantly reduce these risks. Conclusion: The design and construction of an intelligent device prototype was conducted for preparing and transferring radiopharmaceuticals in the hot lab section of medical imaging centers next to the Tc-Mo generator in order to mechanize the process of placing the vials on the generator and then removing the vials containing Tc99m and moving them. This system will significantly prevent unwanted radiation when milking.     Manuscript profile
      • Open Access Article

        5 - An investigation and comparison of effective factors on variations of Honsfield numbers in CT scanners
        Ameneh Abdollahi Qomi Parviz Zobdeh Saeed Karim Khani Zandi
        Objectives:This study was conducted to evaluate effective factors in variation of amount of Handsfield numbers in different CT scanners, considering the importance of CT number equivalence in diagnostic programs and cancer treatment by radiotherapy. Providing the better More
        Objectives:This study was conducted to evaluate effective factors in variation of amount of Handsfield numbers in different CT scanners, considering the importance of CT number equivalence in diagnostic programs and cancer treatment by radiotherapy. Providing the better functional solutions for CT calibration, improving the quality of diagnostic and therapeutic programs, the emphasis on accepted tolerance and controlling the errors resulted from dose calculated by treatment planning systems were studied.Methods:The process performed on raw data obtained during the calibration procedure on ten CT scanners in different radiotherapy centers in IRAN. This quality control tests performed by a selected approved Iranian company.Results: This research focused on CT Number correctness and accuracy tests section in calibration procedure. The factors influencing the variation of Honsfield numbers in CT scans were evaluated by analyzing the obtained data. Data are compared with other factors that cause to alter Handsfeld CT number and reported in previous researches.Creating an error and changing the numbers of CTs causes change in the CT density curve and ultimately effects on treatment plan and the received patient dose. Therefore, it should minimize the error rate by evaluating the effective factors of the TPS. The main factors affecting on Honsfield numbers are: photon energy, the characteristics of materials in phantoms used for calibration of the systems, physical phantom shape and diameter, patient/phantom position and image reconstruction algorithm.Conclusion: It is strongly recommended that a well-documented assessment program is required to ensure Honsfield numbers changes in the confined range of treatments.  Manuscript profile