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Open Access Article
1 - Antihyperlipidemic activity of a unani formulation in high fat diet-induced obese murine model
Md Rafiul Haque Shahid Hussain AnsariArq zeera (AZ), a poly herbal unani formulation has been used traditionally as a remedy for reducing body fat and gastric disorder. The current study was designed to investigate the antihyperlipidemic activity of AZ against rat model of high fat diet (HFD) - induced obe MoreArq zeera (AZ), a poly herbal unani formulation has been used traditionally as a remedy for reducing body fat and gastric disorder. The current study was designed to investigate the antihyperlipidemic activity of AZ against rat model of high fat diet (HFD) - induced obesity. AZ was prepared and administered orally 7.75 ml/kg/twice a day for 4 weeks to HFD- induced obese rat. Body weight and serum biomarkers were evaluated. Stability testing of AZ was also carried out. At the end of study, HFD significantly (p < 0.001) increased body weight, cholesterol, triglycerides, pancreatic lipase activity and malondialdehyde (MDA) levels as compared to normal diet control group. AZ-treated rats significantly (p < 0.001) reduced body weights, cholesterol, triglycerides, pancreatic lipase activity and MDA levels as compared to HFD control. These results suggest that AZ has an antihyperlipidemic action against HFD-induced obesity in rats, possibly through lipid lowering action, reduction of intestinal absorption of dietary fat, and increased antioxidant defense. Manuscript profile -
Open Access Article
2 - Pharmacognostical, physico-chemical and contamination studies of polyherbal formulation “Qurse pudina”
Md Rafiul Haque Nikhat Tara Moumita NandiQurse pudina (QP), a poly herbal formulation which is used for treatment of constipation and gas problems in both Unani and Ayurvedic System of Indian Medicine. In the present article, an attempt has been made to standardize of the poly herbal formulation QP. The QP was MoreQurse pudina (QP), a poly herbal formulation which is used for treatment of constipation and gas problems in both Unani and Ayurvedic System of Indian Medicine. In the present article, an attempt has been made to standardize of the poly herbal formulation QP. The QP was standardized with the help of microscopic, physico-chemical and contamination evaluation. Study revealed that total bacterial and fungal count and Staphylococcus aureus were found under limit, while E. Coli was absent in the formulation. Pesticide residues, aflatoxin and toxic metals such as cadmium and mercury were not found in the formulation. Lead (0.75 mg/kg) and arsenic (0.50 mg/kg) were found under limit. The present outcome from contamination results suggest that QP is a good polyherbal formulation without showing any contamination or toxicity. The data evolved in the present work will aid in identifying the raw drugs used in finished product and will help to fix the scientific standards for QP. Manuscript profile
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