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Open Access Article
1 - Relationship between major dietary patterns and osteoporosis in Iranian postmenopausal women: A case-control study
Behnood Abbasi Paniz Ahmadi Bita Shadbakht Elnaz Zirak SharkeshOsteoporosis is a common skeletal disorder in the elderly characterized by a bone densitylowerthan 2.5 standard deviationsinyoung adults. Diet may play an important role in the pathogenesis of osteoporosis. The aim of this study was to determine the possible relationshi MoreOsteoporosis is a common skeletal disorder in the elderly characterized by a bone densitylowerthan 2.5 standard deviationsinyoung adults. Diet may play an important role in the pathogenesis of osteoporosis. The aim of this study was to determine the possible relationship between major dietary patterns and osteoporosis in Iranian postmenopausal women. A case-control study was conducted on 440 postmenopausal women in Tehran using convenient samplingthat included220 cases and 220 controls. Demographic and anthropometric data, medical history, physical activity and usual dietary intake were collected through interviews. A 147-itemFood Frequency Questionnairewasused to assess dietary patterns.The levelsof physical activity and nutrient intake between the two groupswerecompared.The principal component analysis (PCA)was used to determine dominant dietary patterns. Two dominant dietary patterns (mixed and western) patterns were identified using 33 food groups. There was a significant difference in nutritional status and physical activity between the case and control groups. After adjusting for the effect of possible confounding variables (Model 4), those in the secondtertileof the Western dietary pattern were significantly more likely to have osteoporosis than in the firsttertile(OR=3.87/95% CI=1.13-7.03).The westerndietary pattern was strongly associated with an increased risk of osteoporosis. In addition, no association was found between mixed dietary patterns and osteoporosis. Manuscript profile
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