-
-
-
Open Access Article
1 - Quercetin and its derivatives are potent inhibitors of the dengue virus
Dluya ThagrikiDengue virus belongs to the Flaviviridae family. It causes dengue fever (DF), dengue hemorrhagic fever (DHF), and dengue shock syndrome (DSS). Still, no licensed antiviral or vaccine is available. Quercetin is a plant-derived flavonoid found in fruits and vegetables. Se MoreDengue virus belongs to the Flaviviridae family. It causes dengue fever (DF), dengue hemorrhagic fever (DHF), and dengue shock syndrome (DSS). Still, no licensed antiviral or vaccine is available. Quercetin is a plant-derived flavonoid found in fruits and vegetables. Several in silico and experimental studies revealed quercetin and its derivatives as potent inhibitors of DENV. This review extensively discussed the outcomes of these studies. This review employed PRISMA guidelines for systematic review. Literature was retrieved from PubMed and other databases using the keywords "Dengue virus", "Quercetin", "Quercetin derivatives", "Flavonoids", "Antiviral Activity", "in vitro", "in vivo" and "in silico". Twenty-nine articles were screened; twenty-five met the eligibility criteria and were reviewed. This review is the first insightful and comprehensive document that reveals quercetin and quercetin derivatives are inhibitors of DENV. Quercetin could lead the way in developing antiviral drugs against dengue diseases. Manuscript profile -
Open Access Article
2 - An overview of traditional medicinal plants as dengue virus inhibitors
Dluya Thagriki Upasana RayDengue fever has caused serious health problems around the world. Continents affected include Asia, Europe, North America, and Africa. Dengue fever, dengue hemorrhagic fever, and dengue shock syndrome are diseases caused by DENV. Promising antiviral activity of medicina MoreDengue fever has caused serious health problems around the world. Continents affected include Asia, Europe, North America, and Africa. Dengue fever, dengue hemorrhagic fever, and dengue shock syndrome are diseases caused by DENV. Promising antiviral activity of medicinal plants against DENV has been reported in several experimental studies. These plants are rich in bioactive constituents that have antiviral activity. This review extensively discussed the antiviral activity of these plants against DENV and the phytoconstituents responsible for the observed effects. The review discussed possible targets of these plant extracts or phytochemicals on the biological process of the virus as a potential mechanism for the observed inhibitory effects. Harnessing plants' chemical constituents can lead to the development of an antiviral against DENV. Manuscript profile
List of Articles Dluya Thagriki
-
The rights to this website are owned by the Raimag Press Management System.
Copyright © 2021-2024