Introduction: Identifying the trends and causes of mortality can be a base for health-care policy-making and planning in society. This study aimed at identifying the causes of the mortality of hospitalized patients based on International Classification of Diseases. Methods: This retrospective study was a descriptive-analytical one. Research population included all inpatients died in hospitals under supervision of Semnan University of Medical Sciences during a 5-year period (2011-2016). Sampling was done as the senses and data were collected by a checklist extracted from death registration system of the Treatment Deputy of the university. Data were analyzed in SPSS by applying statistical approaches in the significant level of p≤ 0.05. Results: 8,270 hospital mortalities were registered during the period. 6,370 (76.3%) of dead patients were burghers and 4,450 (53.8%) were male. The most frequent causes of the mortality were cardiovascular diseases (3,201, 38.7%), cancers (1,287, 15.5%), and respiratory diseases (865, 10.5%). There were significant differences among the mortality rates according to patients' gender, residences, and age ranges (p< .001). Conclusion: Chronic and non-communicable diseases were the main causes of the mortality. Health policy-makers can decrease in these diseases by applying screening programs, empowering people and endorsing regulations on safety life style and so on. Keywords: Hospitals, International Classification of Diseases (ICD10), Mortality, Patients, Iran.
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