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Open Access Article
1 - Detection of overtone and combined peaks using Mn/Cu helical star-shaped (pine-tree-like) sculptured thin films in surface-enhanced Raman spectroscopy
Reza Babaei Shokoofe Goli-Haghighi Hadi Savaloni -
Open Access Article
2 - Synthesis, Characterization, and Crystal Structure Determination of Iron(III) Hetero-ligand Complex Containing Chloride, Dimethyl sulfoxide, pyridine-2, 6-dicarboxylate and Water, [Fe(Pydc)(DMSO)(H2O)Cl]
M. Rafizadeh -
Open Access Article
3 - Synthesis, Identification and Calculation of Complex Crystallographic Structure of Cobalt (II) with theLigand Heterocyclic Derived from Pyridine
Mohammad Mahdi Akbarzadeh Khirollah Mehrani Shahriar Ghammamy Vahideh Hadigheh Rezvan -
Open Access Article
4 - Quantum-chemical modeling of the stacking mechanism for the 1H-4H proton transfer in pyridine derivatives. A DFT study
Jumber Kereselidze Marine Kvaraia George Mikuchadze -
Open Access Article
5 - Synthesis and Characterization of New Mercury (II) Complexes with Bidentate Chelating Schiff Base Iminopyridine Ligand
Mohamad Reza Talei Bavil Olyai -
Open Access Article
6 - Synthesis and Molecular Docking studies of Some Tetrahydroimidazo[1,2-a] pyridine Derivatives as Potent α-Glucosidase Inhibitors
Mohammad R. Asghariganjeh Ali A. Mohammadi Elham Tahanpesar Ayeh Rayatzadeh Somayeh Makarem -
Open Access Article
7 - Synthesis of Functionalized Aryl-vinyl Ethers as Building Blocks and Auxiliaries in Organic Synthesis
B. Mohtat L. Pirhadi S. Azimzadeh H. Djahaniani -
Open Access Article
8 - Synthesis and Characterization of New Poly(ether sulfones) from 4,4'-(arylpyridine-2,6-diyl)diphenol and Bis(fluorophenyl)sulfone
Kamran Mahooti Masoud Mokhtary Hassan Kefayati -
Open Access Article
9 - High-Sensitive and Selective Liquid Membrane Electrode for Direct Determination of Trace Amounts of Chromium
Leila Hajiaghababaei Saeid Takalou Forogh Adhami -
Open Access Article
10 - An Expeditious One-pot Synthesis of Imidazo[1,2-a]pyridines using ZnCl2.SiO2 as a Recyclable Heterogeneous Catalyst under Solvent-free Condition
Haleh Sanaeishoar Mina Bashirpour Fouad Mohave -
Open Access Article
11 - One-pot Synthesis of Polysubstituted Indolizine Derivatives
Mohammad Piltan Seyed Amir Zarei Hassan Saydi Ashraf Sadat Shahvelayati -
Open Access Article
12 - Application of N-isocyaniminotriphenyl phosphorane for preparation of heterocyclic acrylate as a key constituent of many industrial and pharmaceutical compounds
Milad Bazaz Rastkar Bita Mohtat Gholam Bagheri Marandi Hoorieh Djahaniani -
Open Access Article
13 - An Efficient Protocol for Synthesis of 2-amino-3cyanopyridine Derivatives using Nano-modified SBA-15
Behrooz Mirza Neda Nasseri -
Open Access Article
14 - Deep Eutectic Solvent Based on Choline Chloride/Urea as an Efficient Catalytic System for the One-Pot Synthesis of Highly Functionalized 1,4-Dihydropyridines and Polysubstituted 4H-Chromenes
Haleh Nouri Masoud Mokhtary -
Open Access Article
15 - Preconcentration of trace amounts of lorazepam in aqueous samples by functionalizing graphene oxide with 2-aminopyridine
ali moghimi Milad AbnikiIn this study, an approach was used to preconcentrate lorazepam in water samples. This study has tried to present a new method of solid phase diffusion extraction of small amounts of pharmaceutical effluents as an indicator of Lorazepam drug in aqueous samples by graphe MoreIn this study, an approach was used to preconcentrate lorazepam in water samples. This study has tried to present a new method of solid phase diffusion extraction of small amounts of pharmaceutical effluents as an indicator of Lorazepam drug in aqueous samples by graphene oxide with 2-aminopyridine and its measurement by visible and ultraviolet spectroscopy in real samples. This method includes a two-phase system in which the donor phase of the aqueous sample contains lorazepam and the acceptor phase is functionalized graphene oxide. Experiments were performed in two stages of extracting water samples including lorazepam drug desorption using ammonia solvent and the desorbed samples were submitted to UV-Vis spectrophotometer for further analysis. This method is cheap, simple and fast, and it is also a sensitive and reliable method for extracting, preconcentrating and measuring small amounts of lorazepam. The effective parameters on drug extraction, which include: the effect of pH, the amount and type of detergent solvent, and the extraction time, have been investigated. The concentration factor is 19, the detection limit of the method is 1.1 µg/L, and the relative standard deviation is 2.17%. Manuscript profile -
Open Access Article
16 - Quantitative structure–activity relationship on a series of imidazole [1, 2-a] pyridinecarboxamide derivatives as anti-tuberculosis agents
Mohsen Nekoeinia Saeed YousefinejadTuberculosis drug resistance is still one of the most important challenges in the treatment of this infectious disease, and therefore the discovery and development of new effective anti-tuberculosis drugs are always of interest to researchers. In this study, Quantitativ MoreTuberculosis drug resistance is still one of the most important challenges in the treatment of this infectious disease, and therefore the discovery and development of new effective anti-tuberculosis drugs are always of interest to researchers. In this study, Quantitative structure – activity relationship (QSAR) analysis was applied on a series of imidazole[1,2-a] pyridinecarboxamide derivatives as anti-tuberculosis agents. The biological activity of the 18 derivatives were estimated by multiple linear regression and artificial neural network approaches. The four molecular descriptors (nCl, MATS8m, BELe4 and GATS8e) were selected by using stepwise multiple linear regression. The best results of artificial neural network were obtained with a 5-5-1 architecture trained with the feed forward backpropagation algorithm. An external test set containing 5 compounds for evaluating the model's predictive ability was used. The results showed that the artificial neural network approach provides better predictive power compared with multiple linear regression. According to the results of this study, electronegativity, atomic masses and molecular geometry have been found to be important factors controlling the anti-tuberculosis activity. Manuscript profile -
Open Access Article
17 - A Novel protocol for synthesis of Hantzsch 1, 4- dihydropyridines using PEG-400 as a reaction medium and under catalyst-free condition
Ali Ezabadi Fatemeh Tosan -
Open Access Article
18 - Novel procedure for preparation of Hantzsch 1, 4- dihydropyridines using PEG-400 as a reaction medium and under catalyst-free condition
Ali Ezabadi Fatemeh Tosan -
Open Access Article
19 - Condensationtion of 3-hydroxy pyridine alkyl isocyanides and dialkyl acetylenedicarboxylate: synthesis of 4H-chromenes
Mahsa Mahpeyma Bita Mohtat -
Open Access Article
20 - Reaction between 3-hydroxy pyridine alkyl isocyanides and dialkyl acetylenedicarboxylate: synthesis of 4H-chromenes
Mahsa Mahpeyma Bita Mohtat -
Open Access Article
21 - Reaction between 3-hydroxy pyridine alkyl isocyanides and dialkyl acetylenedicarboxylate: synthesis of 4H-chromenes
Mahsa Mahpeyma Bita Mohtat -
Open Access Article
22 - Synthesis of some biologically active 2,4’-bipyridine-5-carbonitriles carrying the 4-Aminohenylthio moiety
Ajaypal Prajapati -
Open Access Article
23 - Synthesis, characterization and first application of perovskite LaFeO3 nano particles for the synthesis of tetrahydropyridine derivatives
Melika Eftekhar Iman Khosravi Vahid Jozari -
Open Access Article
24 - Review: Current development on catalytic synthesis and pharmacological applications of 1,4-dihydropyridines
Rajesh Kumar Singh Ketki Sahore Rekha Rana Sahil Kumar Deo Nandan Prasad -
Open Access Article
25 - Nano-BF3/cellulose as a biodegradable novel catalyst for synthesis of highly functionalized tetrahydropyridines
Seyede Azita Fazeli-Attar Bi Bi Fatemeh Mirjalili -
Open Access Article
26 - Fluidized bed photoreactor for the removal of acetaminophen and pyridine using Al-doped TiO2 supported on alumina
Carlos Montalvo Ruby Sheila Gines Denis Cantu Alejandro Ruiz Claudia Aguilar Isai Perez Rosa Maria Ceron -
Open Access Article
27 - PbWO4 nanoparticles: A robust and reusable heterogeneous catalyst for the synthesis of benzopyranopyridines under ultrasonic irradiation
Hossein Shahbazi-Alavi Javad Safaei-Ghomi Ruhollah Talebi -
Open Access Article
28 - Chloroacetic acid-promoted heterocyclic reactions: Efficient preparation of tetrahydropyridines and 2,3-dihydroquinazolin-4(1H)-ones
Malek Taher Maghsoodlou Nourallah Hazeri Elham Fereidooni Sajjad Salahi Nasrin Mahmoudabadi Naeime Khorshidi Jasem Aboonajmi Mojtaba Lashakri -
Open Access Article
29 - ZrP2O7 NPs: A recyclable, efficient heterogeneous catalyst for the synthesis of 1,6-diamino-2-oxo-4-phenyl-1,2-dihydropyridine-3,5-dicarbonitrile derivatives via a multi-component reaction
Javad Safaei-Ghomi Hossein Shahbazi-Alavi Mohammad Reza Saberi-Moghadam Abolfazl Ziarati -
Open Access Article
30 - Spotlight: [Pyridine-SO3H]X: As a multi-versatile ionic liquid
Sima Kalhor -
Open Access Article
31 - A green method for the synthesis of indeno[1,2-b]pyridines using Fe3O4@SiO2@PrSO3H as a nanomagnetic catalyst
Zohreh Kheilkordi Ghodsi Mohammadi Ziarani Alireza Badiei Hossein Vojoudi -
Open Access Article
32 - Preparation and characterization of SnO2-BiVO4-CuO catalyst and kinetics of phenazopyridine photodegradation
Ailin Yousefi Alireza Nezamzadeh-Ejhieh -
Open Access Article
33 - Fabrication of a novel organic-inorganic hybrid nanocatalyst and its application for the synthesis of bis(pyrazolyl)methanes
Abdolkarim Zare Mojtaba Oraki -
Open Access Article
34 - Facile one-pot multicomponent synthesis of 2-amino-6-(2-oxo-2H-chromen- 3-yl)-4-arylpyridine-3-carbonitriles using Brønsted acidic ionic liquid as catalyst under solvent-free conditions
Janardhan Banothu Rajitha Bavantula Peter Crooks -
Open Access Article
35 - A new, green and recyclable poly(4-vinylpyridine)-supported copper iodide nanoparticles catalyst for the synthesis of aryl-14H-dibenzo [a-o] xanthenes
Jalal Albadi Nasir Iravani Moloud Khoshakhlagh -
Open Access Article
36 - Nicotine-based ionic liquid: as a green catalyst for pyridine-catalyzed Huisgen reaction
Ahmed Ali Hullio Ghulam Murtaza Mastoi -
Open Access Article
37 - Preparation, characterization of graphene oxide nano catalyst functionalized copper-metformin complex and investigation of its catalytic activity in synthesis of tetrahydropyridine derivatives in mild condition
Melika EftekharIn this research, at first, the graphene oxide sheets were prepared by the Hummers method and in continuation metformin molecule was linked to the edges of graphene oxide through the nucleophilic reaction of amine moieties of metformin with carbonyl groups of graphene o MoreIn this research, at first, the graphene oxide sheets were prepared by the Hummers method and in continuation metformin molecule was linked to the edges of graphene oxide through the nucleophilic reaction of amine moieties of metformin with carbonyl groups of graphene oxide by covalent bonding, followed by coordination copper metal on nitrogen atoms of metformin and formation of graphene oxide copper-metformin complex. The prepared nanocatalyst was well characterized by various techniques such as FT-IR, XRD, SEM, EDX, TGA and ICP-OES. All analyses confirmed the successful immobilization of this complex on the surface of GO. The synthesized catalyst was applied to evaluate its performance in the synthesis of tetrahydropyridine derivatives by the reaction of aryl aldehydes, aryl amines and ethyl acetoacetate which this method exhibited good catalytic efficiency with a high yield of products. Moreover, the suggested catalyst could be recycled for several times consecutive cycles without a noticeable decrease in its catalytic activity or metal leaching. Manuscript profile -
Open Access Article
38 - Synthesis and characterization of silver (I) complex containing 4′-(4-quinoline)-2,2′:6′,2′′-terpyridine: Thermal behavior, luminescence study, and cytotoxic properties
Badri Zaman Momeni Sanaz Kazemzade Anari Zahra ShahsavariThe reaction of AgNO3 with 4′-(4-quinoline)-2,2′:6′,2′′-terpyridine (qtpy) has been resulted in the formation of new silver (I) complex [Ag(qtpy)(NO3)] (1). The product has been characterized by elemental analysis, infrared Fourier transmis MoreThe reaction of AgNO3 with 4′-(4-quinoline)-2,2′:6′,2′′-terpyridine (qtpy) has been resulted in the formation of new silver (I) complex [Ag(qtpy)(NO3)] (1). The product has been characterized by elemental analysis, infrared Fourier transmission spectroscopy (FTIR), and nuclear magnetic resonance spectroscopy (1H and 13C NMR). The emission spectrum of complex 1 reveals the presence of π→π* transition with a red shift relative to the free ligand due to the coordination of the ligand to silver center. The thermal properties of 1 indicate that the thermal decomposition process occurs in three steps whereas it is stable up to 320 °C. In addition, the cytotoxic effects of 1 against U87-MG human glioblastoma, MCF-7 human breast cancer, SCOV-3 human ovarian cancer cell line, HT-29 human colorectal cancer, and AGO1522 human normal skin fibroblast cell line were carried out using the MTT assay. The anti-cancer activity of 1 against U87-MG human glioblastoma cell line with IC50 of 6.93 μM is more than that of paclitaxel with IC50 of 27.38 μM. Manuscript profile -
Open Access Article
39 - Anticancer activity of vanadium complexes with bipyridine and phenanthroline
طاهره نشاطی افخم مرضیه زارعی دهنوی آنیتا عابدیVanadium is a nonessential mineral of the daily diet that has shown beneficial health effects. In the present research, we synthesized and characterized three vanadium complexes,]VOCl)bpy(2]Cl )1(, ]VOCl)phen(2]Cl )2(, and ]VO)SO4()phen(2] )3(, from the reaction of VCl3 MoreVanadium is a nonessential mineral of the daily diet that has shown beneficial health effects. In the present research, we synthesized and characterized three vanadium complexes,]VOCl)bpy(2]Cl )1(, ]VOCl)phen(2]Cl )2(, and ]VO)SO4()phen(2] )3(, from the reaction of VCl3 and VOSO4 salts with 2,2'-bipyridine)bpy( and 1,10-phenanthroline )phen( ligands. The mentioned complexes were characterized by FT-IR, Mass and UV-Vis spectroscopy. In absorption spectrum of the synthesized compounds, there is a broad weak peak, above 700 nm which is referred to d-d transition of vanadium )IV( center. Moreover, stretching vibration of V=O is appeared around 973-978 cm-1, in IR spectrum. These results confirm the structure of the compounds. Cytotoxic properties of the complexes were checked out on a normal cell NIH3T3 (Rat embryo fibroblast cell) and against three cancer cell lines including HT29 (colon carcinoma), CacoII )colorectal adenocarcinoma(, and T47D )breast cancer cell( by MTT assay and compared with cis-platin. The results indicate compound )1( with low toxicity on normal cells and high cytotoxicity on the cancerous cell lines, is capable of selectively killing properties Manuscript profile -
Open Access Article
40 - Optimization of catalyst for oxidative cross-coupling reaction of pyridine N-oxides and benzofurans for the synthesis of biologically active compounds
ابراهیم کیان مهر رکسانا فضلی مارال غلامحسینیIn this study, oxidative coupling of pyridine N-oxides with benzofurans has been investigated through palladium-catalyzed oxidative coupling reactions. Benzofuran derivatives, especially 2-aryl benzofurans, exhibit many functional and biological properties such as antic MoreIn this study, oxidative coupling of pyridine N-oxides with benzofurans has been investigated through palladium-catalyzed oxidative coupling reactions. Benzofuran derivatives, especially 2-aryl benzofurans, exhibit many functional and biological properties such as anticancer, antifungal, and antimalaria activity. These compounds are also used to treat asthma and rheumatism. 2-Pyridyl benzofurans have electroluminescence properties and are used for imaging of beta-amyloid plaques in Alzheimer's disease. In this paper, a series of compounds with anticipated biological properties are prepared with high efficiency by direct formation of a carbon-carbon bond between the two carbon-hydrogen bonds of benzofuran and pyidine N-oxide derivatives bearing electron donating or withdrawing groups, using palladium acetate as a catalyst and copper acetate and bromide as oxidant Manuscript profile -
Open Access Article
41 - Synthesis of sulfamic acid functionalized-magnetic nanoparticles and application as a retrievable and efficient catalyst for the green synthesis of 1,4-dihydropyridine and 2,3-dihydroquinazoline derivatives
محمد علی بداغی فرد الهام علیمحمدی1,4-Dihydropyridines and 2,3-dihydroquinazolines are heterocyclic compounds that have pharmacological and biological properties and most of their derivatives are produced in pharmaceutical industries. In this study preparation of bissulfamic acid-grafted on silica-coate More1,4-Dihydropyridines and 2,3-dihydroquinazolines are heterocyclic compounds that have pharmacological and biological properties and most of their derivatives are produced in pharmaceutical industries. In this study preparation of bissulfamic acid-grafted on silica-coated nano-Fe3O4 particles (MNPs-TBSA), and their application as a retrievable heterogeneous acidic catalyst for the green synthesis of 1,4-Dihydropyridines and 2,3-dihydroquinazolines is probed. This nanocatalyst is easily separated from the reaction mixture with the assistance of an external magnetic field and reuse for several runs without deterioration in catalytic activity. The morphology, structure, and size of magnetic nanoparticles were characterized via SEM, XRD, EDS, FT-IR and TGA/DTA. Eco-friendly and non-toxic condition, high yield and purity of the desired products, short reaction time along with the ease of the workup procedure outline the advantages of these new methodologies over the earlier ones. Manuscript profile -
Open Access Article
42 - Matrix analysis of corrosion inhibition phenomena: Theoretical technique for inhibitor prediction and pre-selection
Mohsen Lashgari Mohammad-Reza Arshadi Gholam-Abbas Parsafar