Introduction & Objective: Adiponectin with properties similar to exercise increases glucose uptake in muscle and decreases glucose production in the liver. Cinnamon has modulating properties against oxidative stress, blood sugar and obesity. Therefore, considering t More
Introduction & Objective: Adiponectin with properties similar to exercise increases glucose uptake in muscle and decreases glucose production in the liver. Cinnamon has modulating properties against oxidative stress, blood sugar and obesity. Therefore, considering the effect of exercise training on adiponectin gene expression, the effect of high-fat diets on obesity and the effects of cinnamon on weight loss, the present study seeks to answer the question whether six weeks of aerobic exercise and cinnamon extract on adiponectin gene expression in Fat and liver tissues and the mass of these tissues have different effects in male rats fed with a high-fat diet.Materials & Methods: The present study was conducted in the form of a multi-group research project with a control group the average of the research variables among the groups were compared using one-way analysis of variance and Bonferroni supplementary test and independent t-tests and two-way analysis of variance at the significance level p ≥ 0.05 for all tests with the aim of determining the differences between the groups.Results: The results showed the effect of high-fat diet on adverse changes in adiponectin gene expression in adipose tissue and liver, body weight and weight of adipose tissue and liver. Performing aerobic exercise alone, consuming cinnamon extract alone and the interaction of aerobic exercise and cinnamon extract caused favorable changes in the expression of adiponectin gene in adipose tissue and liver and the weight of adipose tissue and liver compared to the high-fat diet group.Conclusion: It seems that from the desirable and accepted physical activities and sports exercises on the Adipose tissue and liver, maybe some food intakes such as cinnamon supplement extract combined with sports exercises have synergy with useful exercises.
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Background & Aim: Adiponectin is a type of adipokine that is involved in sugar and lipid metabolism, this adipokine is in addition to the tissue that it is like and can become. The present study was designed to compare the effect of endurance, resistance and combined ex More
Background & Aim: Adiponectin is a type of adipokine that is involved in sugar and lipid metabolism, this adipokine is in addition to the tissue that it is like and can become. The present study was designed to compare the effect of endurance, resistance and combined exercises on the level of adiponectin gene expression in the hand and leg muscles of Wistar rats.
Materials & methods: The current study is an experimental research in which 40 healthy male Wistar rats were divided into four ten groups of control, resistance training, endurance and combined. Each group did their own exercises for 8 weeks. Finally, hand and foot muscles were examined to measure the adiponectin gene.
Results: The results of the analyzes showed that the level of adiponectin gene expression was different among all groups (P < 0.001). The relative expression of adiponectin gene in all training groups increased significantly compared to the control group (P < 0.001).Also, comparing exercise groups together, combined exercises had the greatest effect and resistance exercise had the least effect. In intra-group comparison, adiponectin gene expression was higher in hand muscle than leg muscle during resistance training (P = 0.047), but gene expression was higher in leg muscle during endurance training (P = 0.029). These two muscles were not significantly different during combined training (P = 0.086).
Conclusion: According to the results of this study, all types of sports training can increase the expression of adiponectin gene, but combined, endurance and resistance training have the greatest effect, respectively.
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Adiponectin is a peptide hormone that is secreted from adipose tissue in humans and is effective on fat and glucose metabolism. Interleukin-6 also has the main role in various types of host defense mechanisms, including immune reactions and acute phase reactions. Theref More
Adiponectin is a peptide hormone that is secreted from adipose tissue in humans and is effective on fat and glucose metabolism. Interleukin-6 also has the main role in various types of host defense mechanisms, including immune reactions and acute phase reactions. Therefore, the aim of the present study was to compare the short-term effects of aerobic exercise and high-fat diet and curcumin extract on the expression of adiponectin and interleukin genes in six muscle tissues of male Wistar rats. For this purpose, 50 two-month-old male rats were prepared and divided into five control groups, high-fat diet, curcumin and high-fat diet, exercise and high-fat diet, curcumin + exercise + high-fat diet. Data analysis was compared using one-way analysis of variance. The mean of intra-group differences was also compared using the one-way statistical test. The results showed that the average expression of the adiponectin gene of the subjects showed a significant difference among the 5 groups. The results of Bonferroni's post hoc test also showed a significant difference between the control group and other groups. Also, the expression of interleukin 6 gene increased in two groups - high-fat diet and high-fat + curcumin diet group compared to the control group. But in two groups of high-fat diet + exercise and high-fat diet + exercise + curcumin group, there was a significant decrease.
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