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        1 - The effect of a session of intense resistance activity with glutamine supplementation on the relative expression of myogenin and myosin creatine kinase genes in the fast-twitch muscle fibers of adult male Wistar rats.
        mansoor mottahedi Tahereh Bagherpoor َArdeshir Zafari nematallah nemati
        Background & Aim: Despite the importance of resistance protocol and glutamine on hypertrophy, their effect on myogenic genes expression process is still unknown. Therefore, the aim of the present study was to investigate the effect of an intense resistance session w More
        Background & Aim: Despite the importance of resistance protocol and glutamine on hypertrophy, their effect on myogenic genes expression process is still unknown. Therefore, the aim of the present study was to investigate the effect of an intense resistance session with glutamine on Myogenin and Myosin creatine kinase gene expression in male Wistar rats. Materials & Methods: 30 8-week-old male rats with an approximate weight of 220±20 were prepared and divided into three groups, control, intense resistance training, and intense resistance training with glutamine, in a simple random manner. The training groups participated in a resistance session of climbing the ramp with 4 sets, 5 repetitions, 30 seconds of rest between repetitions and 2 minutes of rest between sets. Glutamine was once a day powder dissolved in 100 cc of distilled water at a dose of 5.5 grams per kilogram of body weight every day for 5 days. The Extensor Digitorum long muscle tissue was sent to the relevant laboratory to study the expression of Myogenin and Myosin creatine kinase genes. The relative fold change method was used to check gene expression data at a significance level of 5%. Results: The gene expression results showed that myogenin and myosin creatine kinase gene expression levels increased significantly as a result of a high-intensity resistance training session with glutamine compared to the control group, and this value was more pronounced in the resistance training group (p<0.05). Conclusion: It seems that an intense resistance training session is more effective than glutamine on the increase of myogenic genes. Manuscript profile
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        2 - Effect of two types of resistance and functional training programs on myostatin and follistatin of young active men
        sajad khosroshahi bahram abedi abass mehranpour Mojtaba Khansooz
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        3 - Effect of a bout of heavy resistance training on galectin-3 in healthy young men
        Hamid Reza Nayeri khoob
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        4 - The effect of single bout of circuit resistance training on NT-proBNP levels in sedentary men
        Saeid Naraghi Mohammad Ghassami
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        5 - Effects of instability versus high-volume resistance training on thigh muscle cross-sectional area and hormonal adaptations
        Nooshin Mehrpuya Mehrzad Moghadasi
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        6 - Effects of Heavy Duty versus traditional resistance training on thigh muscle cross-sectional area
        Javad Mokaram Bakhtajerdi Mehrzad Moghadasi
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        7 - Comparison of the effect of resistance, endurance and concurrent exercises on adiponectin gene expression in hand and foot muscle tissues of male Wistar rats
        zahra malekian Tahereh Bagherpoor Nematollah Nemati
        Background & Aim: Adiponectin is a type of adipokine that is involved in sugar and lipid metabolism, this adipokine is in addition to the tissue that it is like and can become. The present study was designed to compare the effect of endurance, resistance and combined ex More
        Background & Aim: Adiponectin is a type of adipokine that is involved in sugar and lipid metabolism, this adipokine is in addition to the tissue that it is like and can become. The present study was designed to compare the effect of endurance, resistance and combined exercises on the level of adiponectin gene expression in the hand and leg muscles of Wistar rats. Materials & methods: The current study is an experimental research in which 40 healthy male Wistar rats were divided into four ten groups of control, resistance training, endurance and combined. Each group did their own exercises for 8 weeks. Finally, hand and foot muscles were examined to measure the adiponectin gene. Results: The results of the analyzes showed that the level of adiponectin gene expression was different among all groups (P < 0.001). The relative expression of adiponectin gene in all training groups increased significantly compared to the control group (P < 0.001).Also, comparing exercise groups together, combined exercises had the greatest effect and resistance exercise had the least effect. In intra-group comparison, adiponectin gene expression was higher in hand muscle than leg muscle during resistance training (P = 0.047), but gene expression was higher in leg muscle during endurance training (P = 0.029). These two muscles were not significantly different during combined training (P = 0.086). Conclusion: According to the results of this study, all types of sports training can increase the expression of adiponectin gene, but combined, endurance and resistance training have the greatest effect, respectively. Manuscript profile
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        8 - The effect 8 weeks resistance training on PTP1B expression in Gastrocnemius muscle, insulin resistance and fasting glucose in type 2 diabetic rats
        amin boroomand babisan askari Saqqa Farajtabar Behrestaq Amir Taghipour
        AbstractBackground and Purpose: This experimental study aimed to determine the effect of 8 weeks resistance training on PTP1B expression in gastrocnemius muscle, glucose and insulin resistance in Wistar male's rats with type 2 diabetes. Material and Methods: The populat More
        AbstractBackground and Purpose: This experimental study aimed to determine the effect of 8 weeks resistance training on PTP1B expression in gastrocnemius muscle, glucose and insulin resistance in Wistar male's rats with type 2 diabetes. Material and Methods: The population consisted of all rats, among which 14 were purchased 10-weeks old rats with a 220 &plusmn; 20 g weighing. Then, type 2 diabetes induced by 8 weeks high-fat diet + STZ and divided randomly into resistance training and control groups. Then, the resistance rats participated in 8 weeks resistance training for 5 sessions per week. Fasting glucose, serum insulin and PTP1B expression in gastrocnemius muscle of both groups were measured at 48 hours after last exercise and compared between 2 groups by independent T test. Results: The resistance training improved fasting glucose compared with control subjects. Insulin resistance was significantly increased and PTP1B expression in gastrocnemius muscle significantly decreased in resistance group when compared with control subjects. Conclusion: Based on these data, decreased glucose concentration in exercise group can be attributed to decrease PTP1B expression in gastrocnemius muscle in response to resistance training.Keywords: Resistance training, Gastrocnemius muscle, Type 2 diabetes, PTP1B expression. Manuscript profile
      • Open Access Article

        9 - Comparison of the Effectiveness of Two Training Programs of Resistance Stretching and Plyometric Resistance on Hypertrophy (TGF-β1) and Muscle Strength in Female Handball Players
        zahra ahmadinia sareh hasani bahram abedi Mojtaba Khansooz
        Introduction: The present study was conducted with the aim of comparing the effect of resistance stretching and plyometric resistance exercises on TGF-&beta;1 and muscle strength of female handball players.Methods: In this semi-experimental research, which was conducted More
        Introduction: The present study was conducted with the aim of comparing the effect of resistance stretching and plyometric resistance exercises on TGF-&beta;1 and muscle strength of female handball players.Methods: In this semi-experimental research, which was conducted with a pre-test-post-test design, 36 female handball players in the age range of 18 to 30 years were randomly assigned to three groups of plyometric, stretching and control exercises. Muscle strength measurement and blood sampling were done in two stages, 24 hours before the intervention and 48 hours after the end of the intervention. They commented. The collected data were analized by dependent t-test, covariance and Bonferroni's post hoc test.Results: The results of the study showed that six weeks of plyometric resistance training and stretching resistance training have a significant effect on reducing the serum levels of TGF-&beta;1 and increasing the muscle strength of the upper and lower limbs (P&lt;0.05). Other results showed that there is a significant difference between the plyometric resistance training group and the stretching resistance training group in the levels of TGF-&beta;1, upper and lower limb muscle strength (p&lt;0.05). In addition, the results indicated a greater effect size of plyometric resistance training compared to stretching resistance training on research variables.Conclusion: According to the findings of the present study, it seems that plyometric resistance training can be more effective in reducing TGF-&beta;1 serum levels and increasing muscle strength in female athletes than stretching resistance training. Manuscript profile
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        10 - The Effect of Aerobic-resistance Training on HIF1a Gene Expression in Coronary Artery Disease After CABG
        Azar Hamidi Amir Rashidlamir Rambod Khajei Mehdi Zarei Ahmad Zendedel
        Coronary heart disease (CAD) is one of the most important causes of death in most countries, including Iran. Post-operative exercise coronary artery bypass grafting (CABG), and its adaptations, increase skeletal and cardiac capillary density associated to developing new More
        Coronary heart disease (CAD) is one of the most important causes of death in most countries, including Iran. Post-operative exercise coronary artery bypass grafting (CABG), and its adaptations, increase skeletal and cardiac capillary density associated to developing new capillaries called angiogenesis and improve cardiovascular function and functional ability. This study aimed to investigate the effect of cardiac rehabilitation on HIF1- &alpha; gene expression in post-CABG coronary patients. The sample contained 30 men aged 45-60 years who underwent bypass surgery. They were randomly divided into experimental (n = 15) and control (n = 15) groups. The experimental group performed aerobic resistance training for eight weeks (3 sessions per week), and the control group did not. Blood samples were taken 48 hours before starting the first training session and 48 hours after the last training session, while all subjects were fasting. Independent and paired t-test and Shapirovilk test were used to analyze the data at a significant level of 0.05 in SPSS version 21. The results showed that the HIF-1&alpha; gene expression in the aerobic resistance group also increased in the control group which was statistically significant (p &lt; /em&gt; = 0.001) as well as before and after changes in the exercise group. The control group was significant (p &lt; /em&gt; = 0.001). Due to the findings of the present study, it can be concluded that combined (aerobic-resistance) exercises may increase cardiovascular function by increasing HIF1&alpha;-1 gene expression and the growth of new capillaries called angiogenesis and by increasing circulation. It improves patients' quality of life after CABG. Manuscript profile
      • Open Access Article

        11 - The Effect of Eight Weeks of Aerobic Resistance Training on ABCG8 Gene Expression and Lipid Profile in CABG Patients
        Farida Sadeghi Fazel Amir Rashidlamir Rambod Khajeie Akbar Safipour Afshar
        Coronary heart disease is one of the leading causes of death in today's societies. It is associated to the exercise activity and the expression of some genes involved in the blood cholesterol transmission. Adenosine triphosphate-dependent box protein 8 is a member of AB More
        Coronary heart disease is one of the leading causes of death in today's societies. It is associated to the exercise activity and the expression of some genes involved in the blood cholesterol transmission. Adenosine triphosphate-dependent box protein 8 is a member of ABC transporter family which plays a key role in the metabolism of high-density lipoprotein cholesterol and cholesterol. This study aimed to evaluate the effect of eight weeks of aerobic resistance training on ABCG8 gene expression and lipid profile in CABG patients. 30 men with CABG patients voluntarily selected and randomly divided into the experimental (n = 15) and control (n = 15) groups. The experimental group performed the aerobic resistance training for eight weeks (3 sessions per week) and the control group did not. Blood samples were taken 48 h before the first training session and 48 h after the last training session, while all subjects were fasting. Independent and paired t-test used to analyze the data at a significant level of 0.05. The present study's results showed that the aerobic resistance training group showed a significant increase in the ABCG8 mRNA expression and a significant decrease in LDL-C, triglyceride, and HDL-C as compared to the control group. Due to the findings of present study, it can be concluded that aerobic resistance training by increasing ABCG8 gene expression has a great effect on increasing the cholesterol transfer process; thus, it may improve the CABG patients and prevent cardiovascular diseases. Manuscript profile
      • Open Access Article

        12 - The Effect of 12 Weeks of Circuit Resistance Training with Three Different Intensities of Equal Volume on Some Hemodynamic Factors of Obese Men
        Saber Niazi Hamid Rajabi Sadegh Amani
        Obesity is one of the causes of cardiovascular disease and exercise can play a role in modulating this risk. Therefore, this study was aimed at investigating the effect of 12 weeks of circuit resistance training with three different intensities of equal volume on some h More
        Obesity is one of the causes of cardiovascular disease and exercise can play a role in modulating this risk. Therefore, this study was aimed at investigating the effect of 12 weeks of circuit resistance training with three different intensities of equal volume on some hemodynamic factors on obese men. Forty four obese men aged 23 to 33 years (BMI&ge;30, (WHtR)&gt; 0.5) in four control groups: low-intensity circuit resistance training (40% Rm1), medium (60% Rm1) and high (Rm1) 80% (11 = number in each group) with equal volume. Before and after 12 weeks of resting heart rate training, resting systolic and diastolic blood pressure and pressure product rate were measured. Two-way analysis of variance (ANOVA) and Bonferroni post hoc test were used to examine the intragroup changes using t-test and comparison of groups (P&le;0.05). It seems that 12 weeks of circuit resistance training has a positive effect on lowering blood pressure and pressure product rate besides improving indicators related to heart function. High-intensity exercise is likely to have a greater effect on resting heart rate, systolic and diastolic blood pressure, and double heart rate. Manuscript profile
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        13 - The Effect of Eight Weeks of Aerobic Resistance Training on LXR Gene Expression and Serum TNFα Levels in CABG Patients
        Fahimeh Parhizi Amir Rashidlamir Rambod khajei Mohammd Reza Ramzanpour Mohsen Vazifehdoost
        Cardiovascular diseases are one of the leading causes of death in the world. According to the American Heart Association, the prevalence of the cardiovascular diseases has an inflammatory basis, and general inflammation plays a central role in the development of atheros More
        Cardiovascular diseases are one of the leading causes of death in the world. According to the American Heart Association, the prevalence of the cardiovascular diseases has an inflammatory basis, and general inflammation plays a central role in the development of atherosclerosis. The purpose of this study was to investigate the effect of eight weeks of aerobic resistance training on LXR gene expression and serum TNF&alpha; levels in CABG patients. Twenty-four men who underwent bypass surgery were voluntarily selected and randomly divided into experimental (n=12) and control (n=12) groups. The experimental group performed aerobic resistance training for eight weeks (3 sessions per week) and the control group did not. Blood samples were taken 48 hours before the start of the first training session and also 48 hours after the last training session while all subjects fated. Independent and paired samples Student's t-test and Shapirovilk test were used to normalize the data at a significant level of 0.05. The results of the present study showed that the training group experienced a significant increase in LXR mRNA gene expression and a decrease in serum TNF&alpha; levels as a result of eight weeks of aerobic resistance training compared to the control group. The same changes were seen as the within group differences in the pre-test and post-test in the training group. The findings of this study showed that an eight-week combined aerobic and resistance training program could regularly increase the LXR gene expression and decrease serum TNF&alpha; levels in CABG patients Manuscript profile
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        14 - The effect of 8 weeks of increasing resistance training and a non-training period on left ventricular end-diastolic volume (LVEDV) in sedentary women.
        Alireza Babaei Mazreno
        The aim of the current research was the effect of 8 weeks of increasing resistance training and a period of non-training after that on the left ventricular LVEVD index of sedentary women. In this semi-experimental research that was conducted in a field-laboratory manner More
        The aim of the current research was the effect of 8 weeks of increasing resistance training and a period of non-training after that on the left ventricular LVEVD index of sedentary women. In this semi-experimental research that was conducted in a field-laboratory manner, 32 sedentary women who were able to regularly participate in the exercise protocol were selected by simple random sampling and randomly divided into 2 groups: 1- Resistance exercise group (16 people ), 2- control group (16 people). In the present study, before the implementation of the training program, all the anthropometric characteristics, body composition and structural and functional indicators of the left ventricle of the subjects were measured and recorded in three stages under the same conditions. Variable left ventricular end-diastolic volume (LVEDV), by a cardiologist with echocardiography using M-Mode, Spectral Doppler, Color Doppler (2-D) methods and in a special echocardiography room in 3 stages (before exercise, after the end of 8 weeks The resistance training program was measured after 4 weeks of non-training after training. It was also measured before echocardiography. All training programs including 3 training days per week and every day for 90 minutes were implemented in the sports hall of Azad University, Yazd branch. This program was implemented for 8 weeks from low to high intensity, taking into account the principle of overload and increasing the intensity of training. Finally, the results showed that eight weeks of increasing resistance training was significant on the left ventricular end-diastolic volume (LVEDV) of sedentary women, and it reduced the positive effects of increasing resistance training on the left ventricular end-diastolic volume. Manuscript profile
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        15 - The Effects of acute consumption of BCAA,s on inflammatory and muscle damage indicators following intense resistance training session in girls professional athletes
        Marjaneh  Mehrabi Bahram Abedi Mojtaba Khansooz
        The purpose of the present study was to determine the effect of acute BCAA supplementation on some inflammatory indicators and muscle damage following an intense resistance training session in female athletes. In this semi-experimental research with a pre-test-post-tes More
        The purpose of the present study was to determine the effect of acute BCAA supplementation on some inflammatory indicators and muscle damage following an intense resistance training session in female athletes. In this semi-experimental research with a pre-test-post-test design, 20 female athletes were randomly divided into 2 groups of 10: resistance training group with BCAA supplementation and resistance training group with placebo supplementation, one in the morning and one in the evening. A bout of resistance activity including 10 sets of eight repetitions of squats with 70% of 1RM using the Smith machine and a 3-minute rest between each set was performed by all participants. After completing the squat protocol, participants performed five consecutive sets of 20 repetitions (10 repetitions of split body weight jumps) with two minutes of rest between each set. The obtained data were analyzed using the dependent t-test and the covariance test with Benferroni's post hoc test using spss version 22 software. The results of the study showed that the serum levels of creatine kinase and the amount of delayed muscle pain and stiffness immediately, 24 and 48 hours and the serum levels of interleukin 6 immediately after intense resistance activity increased significantly compared to the baseline state. Also, the plasma levels of creatine kinase and the level of delayed muscle pain and stiffness in 24 hours and the level of interleukin-6 plasma levels have reached their peak after intense resistance activity, and this level was significantly higher than 48 and 72 hours after intense resistance activity. The present study showed that the consumption of BCAA supplement (0.22 g/kg) before and after exercise has no beneficial effect in reducing injury, muscle pain and inflammation in resistance trained women after senteric resistance training. Manuscript profile