Introduction: Overweight and obesity are the most common metabolic disease in the world and cause or exacerbate many of the diseases that are associated with reduced quality of life. Exercise training increases skeletal muscle capillary density, but the molecular mechan More
Introduction: Overweight and obesity are the most common metabolic disease in the world and cause or exacerbate many of the diseases that are associated with reduced quality of life. Exercise training increases skeletal muscle capillary density, but the molecular mechanisms of this process are not yet clear. The aim of this study was to determine the effect of eight weeks circuit resistance training on serum vascular endothelial growth factor (VEGF) and Factors Atherogenic of fat in obese men. Materials and Methods: In this quasi-experimental study, 22 obese men were randomly divided into two groups of exercise and control. Training program was consists of three sessions per week for eight weeks with intensity between 60 to 80 percent of 1RM. Venous blood samples the pre-test and post-test for measured of VEGF and Factors Atherogenic was used. Data were analyzed by ANOVA test using SPSS software version 23. Results: The results showed that VEGF levels increased from 1628.75 to 1762.93, which Evaluation of intergroup changes was significantly higher in the exercise group compared to the control group (p <0.001). The results showed that Factors Atherogenic which Evaluation of intergroup changes was significantly decrees in the exercise group compared to the control group (p <0.001).Conclusion: circuit resistance training can increase levels of SIRT1 and PGC-1α, and reduce weight and fat percentage.
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