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Open Access Article
1 - Antioxidant effect of pistachio peel extract and aerobic exercise on superoxide dismutase, catalase and malondialdehyde in the latissimus dorsi muscle of overweight Wistar rats
Mohsen Sahebi Mohamad ali Azarbayjani Maqsood PiriAim: The objective of this study was to detect the antioxidant effect of pistachio green hull extract and aerobic exercise on superoxide dismutase, catalase, and malondialdehyde in the external vastus muscle of overweight Wistar rats.Method: This study is in the categor MoreAim: The objective of this study was to detect the antioxidant effect of pistachio green hull extract and aerobic exercise on superoxide dismutase, catalase, and malondialdehyde in the external vastus muscle of overweight Wistar rats.Method: This study is in the category of interventional studies and is included in the category of experimental studies. In this study, 30 Wistar (female) rats with an age range of 12-13 weeks and a weight range of 180 to 200 grams were present. The samples are in 5 groups including: 1- control group (Con), obese control group (OB-Con), obese group and aerobic exercise (OB-AT), obese group and pistachio skin extract (OB-PGH), obese group and Pistachio green hull extract and aerobic exercise (OB-PGH-AT) were divided.Findings: Exercise had a significant effect on muscle dismutase superoxide concentration (F=10.61, P=0.004, ƞ=0.347). But receiving pistachio skin extract had no significant effect on muscle dismutase suboxide concentration (F=2.42, P=0.135, ƞ =0.108). The interaction between exercise and pistachio skin extract had no significant effect on muscle dismutase suboxide concentration (F=0.75, P=0.396, ƞ=0.036). Exercise had a significant effect on catalase concentration (F=160.98, P=0.001, ƞ=0.889). Taking pistachio skin extract also had a significant effect on muscle catalase concentration (F=5.04, P=0.036, ƞ=0.201). But the interaction between exercise and pistachio skin extract had no significant effect on muscle catalase concentration (F=1.84, P=0.190, ƞ=0.084). Exercise had a significant effect on muscle malondialdehyde concentration (F=57.66, P=0.001, ƞ=0.742). Taking pistachio skin extract also had a significant effect on muscle malondialdehyde concentration (F=80.29, P=0.001, ƞ=0.801). However, the interaction between exercise and pistachio skin extract had no significant effect on muscle malondialdehyde concentration (F=0.004, P=0.949, ƞ=0.001).Conclusion: In addition, adding PGH supplements to aerobic exercise can reduce oxidative damage and increase the antioxidant enzymes catalase and superoxide dismutase. Induction of obesity increases inflammatory markers and oxidative stress in muscle. Manuscript profile -
Open Access Article
2 - The effect of Purslane seed supplement and aerobic training on mitochondrial biogenesis markers and DNA damage in kidney tissue in rats toxicated by hydrogen peroxide
Forogh foladi Mohamad ali Azarbayjani Maghsoud Peeri Farshad GhazalianIntroduction: Various treatment methods such as herbal supplements and lifestyle modification including regular exercise have been recommended to reduce oxidative damage and improve antioxidant defense. The aim of this study was to evaluate the effect of Purslane seed s MoreIntroduction: Various treatment methods such as herbal supplements and lifestyle modification including regular exercise have been recommended to reduce oxidative damage and improve antioxidant defense. The aim of this study was to evaluate the effect of Purslane seed supplement and aerobic training on mitochondrial biogenesis markers and DNA damage in kidney tissue of rats toxicated by hydrogen peroxide. Materials and Methods: To implementation of this experimental research, 54 male wistar rats randomly were divided into 9 groups. All groups received 100 mg/kg body weight of hydrogen peroxide (H2O2) for 14 days intraperitoneal. Rats in supplemented groups received hydrophilic Purslane seed with doses of 50, 200 and 400 mg per day by gavage method. Aerobic training was performed on a treadmill at a speed of 23 m/min, 30 min/day, 5 days/week for eight weeks. Data were analyzed using by two-way ANOVA and Bonferroni post hoc test at P<0.05.Results: The results showed that purslane seeds and the combined intervention of purslane seeds with aerobic training led to significant increase in the levels of O-6-methylguanine-DNA-methyltransferase and oxidant-prooxidant balance (PAB), as well as significant decrease the amounts of adenosine triphosphate (ATP) and malondialdehyde (MDA) in kidney tissue of rats toxicated by hydrogen peroxide (P=0.001).Conclusion: It seems that aerobic exercise with purslane seeds can help to reduce the oxidative damage of kidney. Manuscript profile -
Open Access Article
3 - A review on the anti-inflammatory effect of octepamine supplementation following exercise in metabolic disorders
raana mahmudi Mohamad ali Azarbayjani Maghsoud Peeri Parvin FarzanegiBackground: Obesity is a metabolic disease associated with mild inflammation. It seems that the origin of obesity-induced inflammation is the penetration of macrophages into adipose tissue. The aim of this study was review on the anti-inflammatory effect of octepamine s MoreBackground: Obesity is a metabolic disease associated with mild inflammation. It seems that the origin of obesity-induced inflammation is the penetration of macrophages into adipose tissue. The aim of this study was review on the anti-inflammatory effect of octepamine supplementation following exercise in metabolic disorders. Methods: In this study, the keywords Octapamine, Exercise training, Metabolic disorders were searched in all databases including Science of Web, Pubmed, Google, Magiran, SID.IR, scholar risk factors, etc., without year restrictions. Then the articles were categorized based on exercise training and octapamine supplementation in metabolic disorders.Findings: The results of the present study showed that deep-fried oils lead to an increase in NFkB gene expression in the adipose tissue of rats poisoned with deep-fried oil, however it appears that training and octapamine consumption alone lead to a decrease in NFkB, and increases in IL-4 and IL-10 gene expression levels in the heart tissue of rats poisoned with deep-fried oils.ConclusionThe results of the present study showed that deep-fried oils lead to an increase in NFkB gene expression in the adipose tissue of rats poisoned with deep-fried oil, however it appears that training and octapamine consumption alone lead to a decrease in NFkB, and increases in IL-4 and IL-10 gene expression levels in the heart tissue of rats poisoned with deep-fried oils Manuscript profile -
Open Access Article
4 - The effect of resistance exercises and medicinal plants on muscle atrophy
Soheil Abdollahi Mohammad Ali Azarbayjani Maqsood Peeri Saleh RahmatiSkeletal muscle atrophy is one of the most common muscle disorders that severely reduces the quality of life. Regular physical activities, especially resistance exercises, are one of the most important non-pharmacological interventions for the prevention and treatment o MoreSkeletal muscle atrophy is one of the most common muscle disorders that severely reduces the quality of life. Regular physical activities, especially resistance exercises, are one of the most important non-pharmacological interventions for the prevention and treatment of muscle atrophy. By increasing anabolic hormones, resistance training inhibits protein degradation signaling pathways and activates protein synthesis signaling pathways and reduces muscle atrophy. Many medicinal plants can also reduce muscle atrophy by inhibiting the signaling pathway of protein degradation and activating the signaling pathway of protein synthesis. Turmeric, tribulus terrestris, rice bran and ginseng are examples of medicinal plants that can inhibit muscle atrophy. According to the common mechanisms of resistance training and medicinal plants on the process of muscle atrophy, the results of studies show that these two interventions prevent muscle atrophy, especially in the conditions of skeletal muscle wasting diseases, by affecting the signaling pathway of muscle protein synthesis and degradation. do These two interventions in combination with each other have a synergistic effect and strengthen each other's effect. Therefore, the use of medicinal plants along with resistance exercises is an efficient way to maintain muscle mass. Manuscript profile -
Open Access Article
5 - A review on determining the effect of aerobic exercise and octapamine supplementation on vascular function following metabolic disorders
fatemeh shokri Mohamad ali Azarbayjani Maghsood Peeri Farshad GhazalianBackground: Obesity, which is a characteristic of metabolic syndrome. Based on this, obese people are in a mild inflammation condition due to abnormal secretion of inflammatory mediators. There are several mechanisms for the occurrence of this inflammation, the most imp MoreBackground: Obesity, which is a characteristic of metabolic syndrome. Based on this, obese people are in a mild inflammation condition due to abnormal secretion of inflammatory mediators. There are several mechanisms for the occurrence of this inflammation, the most important of which is the increasing production of inflammatory mediators and the reduction of anti-inflammatory mediators. Deep-heated oils, as an integral part of the diet, are one of the causes of inflammation in obesity. Studies show that with the development of obesity, capillary formation in adipose tissue does not occur in line with changes in cell size. Therefore, fat tissue in obese people is always associated with lack of oxygen and the secretion of inflammatory mediators causes systemic inflammation.Methods: To conduct the present study, the keyword terms Aerobic Exercise, Metabolic disorders, and Octapamine were searched in all databases, including Science of Web, Pubmed, Google, Magiran, SID.IR, scholar risk factors, etc., with no year restrictions. The articles were then categorized based on the effect of performing aerobic exercise and octapamine supplementation on vascular function following metabolic disorders.Findings: The results show that aerobic exercise and octapamine supplementation improve the process of angiogenesis of visceral fat tissue that has been disrupted by deep-fried oils and reduces the damage caused by feeding with deep fried oils.Conclusions: Taking deep-heated oils leads to disturbances in fat metabolism in visceral fat tissue, and in this condition, capillary formation in visceral fat tissue decreases significantly and insulin resistance increases. As a result, this is associated with functional disorders of visceral fat tissue. However, aerobic exercise and octapamine improve the angiogenesis process of visceral fat tissue and reduce the damage caused by feeding with deep-heated oils. Manuscript profile
List of Articles Mohammad Ali Azarbayjani
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