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        1 - Effect of Eight Weeks of Endurance Training with Pistacia Atlantica Extract on the Expression of Ghrelin Gene in the Intestinal Tissue of Rats
        Saleh Rahmati-Ahmadabad
        Introduction: Impaired energy balance causes various diseases such as obesity, diabetes, etc. Many peptides are involved in regulating energy balance in the body, of which ghrelin is one of the most important. This study investigates the effect of endurance trainin More
        Introduction: Impaired energy balance causes various diseases such as obesity, diabetes, etc. Many peptides are involved in regulating energy balance in the body, of which ghrelin is one of the most important. This study investigates the effect of endurance training and Pistacia Atlantica extract (Baneh) (as a plant rich in fatty acids) on ghrelin gene expression in the intestinal tissue of female rats. Materials and methods: In this experimental study, 20 adult female Wistar rats were selected and randomly divided into four groups: 1) saline control, 2) saline training, 3) Baneh control, and 4) Baneh + training. Groups 2 and 4 trained on a rodent treadmill for eight weeks (five days a week, each session for 60 minutes at a speed of 25 m / min with a zero slope) while groups 1 and 3 did not. Groups 3 and 4 received Pistacia Atlantica extract and groups 1 and 3 received saline solution before exercise as a gavage (1 mg per gram of body weight). Rats were anesthetized and biopsied 72 hours after the last training session in the fasting state. Data were analyzed using a two-way analysis of variance and p < 0.05 was considered significant. Findings: Eight weeks of aerobic training decreased ghrelin gene expression in rats intestinal tissue (p < 0.001) but its expression increased in response to Pistacia Atlantica use (p < 0.001). Conclusion: The use of a high-fat diet (Baneh extract) increased the expression of the ghrelin gene in intestinal tissue. Eight weeks of aerobic training moderated this increase. Manuscript profile
      • Open Access Article

        2 - The effect of resistance exercises and medicinal plants on muscle atrophy
        Soheil Abdollahi Mohammad Ali Azarbayjani Maqsood Peeri Saleh Rahmati
        Skeletal muscle atrophy is one of the most common muscle disorders that severely reduces the quality of life. Regular physical activities, especially resistance exercises, are one of the most important non-pharmacological interventions for the prevention and treatment o More
        Skeletal muscle atrophy is one of the most common muscle disorders that severely reduces the quality of life. Regular physical activities, especially resistance exercises, are one of the most important non-pharmacological interventions for the prevention and treatment of muscle atrophy. By increasing anabolic hormones, resistance training inhibits protein degradation signaling pathways and activates protein synthesis signaling pathways and reduces muscle atrophy. Many medicinal plants can also reduce muscle atrophy by inhibiting the signaling pathway of protein degradation and activating the signaling pathway of protein synthesis. Turmeric, tribulus terrestris, rice bran and ginseng are examples of medicinal plants that can inhibit muscle atrophy. According to the common mechanisms of resistance training and medicinal plants on the process of muscle atrophy, the results of studies show that these two interventions prevent muscle atrophy, especially in the conditions of skeletal muscle wasting diseases, by affecting the signaling pathway of muscle protein synthesis and degradation. do These two interventions in combination with each other have a synergistic effect and strengthen each other's effect. Therefore, the use of medicinal plants along with resistance exercises is an efficient way to maintain muscle mass. Manuscript profile