Background and Objectives: Leptospirosis is one of the most significant zoonotic diseases with intensive frequency worldwide. The infection of individuals in any given slaughter house is fortuitous and it will normally occur after a direct contact with animals’ urine or their carcass. This study was aimed to evaluate the rate of serum infection with the various strains of Leptospira interrogance among the industrial slaughter house personnel of Zanjan province. Material and Methods: In this cross sectional descriptive study, 98 serum samples were collected from the personnel of the industrial slaughter house placedin Zanjan province throughout 2011. After sampling, all the serum samples were subjected to microscopic agglutination Test (MAT) by seven live Leptospiral serotypes (made by Razi Vaccine and Serum Institute, Karaj, Iran). Results: The results obtained from study of the serum samples indicated that 34 (34.7%) samples had positive reactions to one or more serovars. The remaining samples (65.3%) were serologically negative.Sejroe Hardjo, Grippotyphosa, and Canicola serovars were the most prevalent serovars of Leptospira with the frequency rates of %47.8, %15.2, and %13, respectively. Conclusions: Since there is a high frequency rate of seropositive cases in the personnel, there is a high possibility for transmitting of the contamination into the food cycle. Therefore, a vaccination program for the personnel is recommended.
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