Diabetic neuropathy is a peripheral nerve disorder in people with diabetes that affects the nerve fibers in these patients. This study has been perforemd aiming to investigate the effect of eight weeks of aerobic and resistance training on serum concentrations of nerve More
Diabetic neuropathy is a peripheral nerve disorder in people with diabetes that affects the nerve fibers in these patients. This study has been perforemd aiming to investigate the effect of eight weeks of aerobic and resistance training on serum concentrations of nerve growth factor and neurotrophin 4 in women with diabetic neuropathy. Forty-two diabetic women with the avergae age of 47.97 ±4.58 years were selecetd by convenience sampling. Then, they were randomly divided into three groups including the control, aerobic and resistance training groups (15 people in each group). NGF and NT4 levels were measured by sandwitch ELISA before and after training . The training program was done for eight weeks (three sessions a week) with 50-70% of heart rate reserve. Resistance training was also continued for eight weeks and three sessions a week with an intensity of 40-60% of a maximum repetition. Repeated measures ANOVA test was used for data analysis. The results of the significant increase in serum NGF levels were compared in aerobic (p=0.001) and resistance (p=0.001) groups after eight weeks; the changes were not significant compared to the control group (p≤0.05) and in comparison of the two mentioend groups (P=0.50).Also, significance of the increase in serum NT4 levels was comapred in aerobic (p=0.015) and resistance (p=0.153) groups after eight weeks; the changes in the groups were significant compared to control group, but not comaprd to each other (p=1.00). Aerobic resistance training seems to have a protective effect on progression of diabetic neuropathy, and it can even slow or improve the progression of the disease.
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Gamma-factor progesterone proliferation activating receptors are a ligand-activated transcription factor playing an important role in lipid metabolism. The present study was aimed at evaluating the effect of eight weeks of aerobic-resistance training on the expression o More
Gamma-factor progesterone proliferation activating receptors are a ligand-activated transcription factor playing an important role in lipid metabolism. The present study was aimed at evaluating the effect of eight weeks of aerobic-resistance training on the expression of gamma progesterone proliferator-activating receptor gene in patients with coronary artery bypass grafting. The research method was quasi-experimental and pre-test-post-test. The statistical population included all patients with coronary artery bypass grafting in Mashhad (Iran). Height 1.58 ± 0.03 (m), weight 68.11 ± 5.54 (kg), body mass index (BMI) 27.18 ± 2.47 (2 kg / m2) and disease history 75 8.75 ± 25/20 (month) were formed after coronary artery bypass surgery. According to the inclusion criteria, they were divided into experimental (14) and control (12) groups. Data were analyzed using independent t-test and paired t-test at the significance level of P≥0.05 and SPSS software version 21. The results showed that eight weeks of aerobic-resistance training increased the expression of PPARɣ gene in the combined training group compared to the control group (P = 0.001). Moreover, the results of the correlation test showed that the increase in PPAR gene expression in the combined training group had a significant increase in the post-test compared to the pre-test (P = 0.001), not significant in the control group (p = 0.081). The data of the present study showed that aerobic- resistance training with increasing PPARɣ gene expression could be effective in fat metabolism and related processes in patients with coronary artery bypass grafting.
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