تأثیر مکمل‌سازی گلوتامین، بر عملکرد رشد و وضعیت آنتی‌‌اکسیدانی در جوجه‌های گوشتی درگیر با سندرم افزایش فشار خونی ریوی (آسیت)

Subject Areas : Camel

M. Fathi ¹ , T. Tanha ² , M. Daneshyar ³

1 - Department of Animal Science, Faculty ofAgriculture, Payame Noor University, Tehran, Iran
2 - Department of Animal Science, Faculty ofAgriculture, Payame Noor University, Tehran, Iran
3 - Department of Animal Science, Uremia University, Uremia, Iran

Received: 2013-11-28 Accepted : 2014-01-15 Published : 2014-09-01

Keywords: آسیت, آنزیم های آنتی‌اکسیدان, گلوتامین, پرکسیداسیون لیپید,

Abstract :

مطالعه حاضر با تأکید بر توان دفاعی گلوتامین بر وضعیت آنتی‌اکسیدانی پلاسما و کبد، تغییرات سطوح پراکسیداسیون چربی(MDA)، وضعیت آنتی‌اکسیدانی کل پلاسما (TAS) و فعالیت آنزیم‌های آنتی‌اکسیدان (SOD) و آنزیم وابسته به گلوتاتیون (GPX) در پلاسما و کبد جوجه‌های گوشتی در گیر با سندرم آسیت، انجام شد. نمونه برداری از خون و بافت کبد در روزهای 21 و 42 انجام شد. در پایان آزمایش، از هر قفس، 2 جوجه، به طور تصادفی انتخاب شده و بعد از کشتار، قبل آنها برداشته شد و بطن راست و بطن چپ از ناحیه سپتوم، جدا گشته و نسبت بطن راست به کل بطن‌ها (RV/TV)، نیز محاسبه گشت. میانگین خوراک مصرفی، افزایش وزن حاصله و ضریب تبدیل غذایی نیز به طور هفتگی، از روز 15، اندازه‌گیری شدند. نتایج نشان داد که، مکمل‌سازی گلوتامین سبب بهبود ضریب تبدیل غذایی شد (05/0P<). علاوه بر این، مکمل‌سازی گلوتامین در پرندگان آسیتی، سبب کاهش معنی‌دار MDA در پلاسما و بافت کبد گشت. همچنین، گلوتامین، سبب افزایش هم زمان فعالیت آنزیم GPX در پلاسما و بافت کبد شد. فعالیت آنزیم SOD در پلاسما و کبد، به طور معنی‌داری تحت تأثیر گلوتامین قرار نگرفت (05/0P>). علاوه بر این، مکمل‌سازی گلوتامین، سبب کاهش معنی‌دار تلفات آسیتی و RV / TV شد.

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