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  • List of Articles


      • Open Access Article

        1 - The Effect of Aerobic Exercise Training and Curcumin on Aplin Levels, Insulin Resistance and Glucose in Rats with Type 2 Diabetes
        Morteza Ebrahimzadeh Kamal Azizbeigi Khalid Mohammad Zadeh Salamat Saman Pashaie
        Introduction: Previous studies have shown the positive effect of aerobic exercise and curcumin on diabetes. The aim of this study was to investigate the effect of aerobic exercise with and without curcumin supplementation on apelin levels, insulin resistance, and glucos More
        Introduction: Previous studies have shown the positive effect of aerobic exercise and curcumin on diabetes. The aim of this study was to investigate the effect of aerobic exercise with and without curcumin supplementation on apelin levels, insulin resistance, and glucose in rats with type 2 diabetes. Materials and methods: Forty male rats were randomly divided into 5 groups of 8 including healthy control, diabetic control, diabetes + curcumin, diabetes + aerobic exercise, diabetes + curcumin + aerobic exercise. After the intervention, the animals were sacrificed based on the name of the group, and the desired variables were measured in the collected plasma samples. Data were analyzed by using one-way analysis of variance and a P value less than 0.05 was considered as a significant difference. Findings: The results showed that moderate-intensity aerobic exercise increased the levels of apelin (P<0.05) and decreased insulin resistance (P<0.05) and glucose (P<0.05) in the plasma of diabetic rats. The use of curcumin also increased the levels of apelin (P<0.05) and decreased insulin resistance (P<0.05) and glucose (P<0.05) in the plasma of diabetic rats. Conclusion: Moderate-intensity aerobic exercise can be a good way to lower blood sugar and to prevent from increasing it in diabetic patients. Also, taking curcumin in the range of health values along with aerobic exercise can affect better on the results. Manuscript profile
      • Open Access Article

        2 - The Effect of Two Types of Continuous and Interval Training on Fatty Liver Markers in Women with Type 2 Diabetes
        Nafiseh Ghannadzadeh Bahram Abedi
        Introduction: Fatty liver is recognized as a pathophysiological condition in people with type 2 diabetes. The aim of the present study was to investigate the effect of exercise (intermittent and periodic) training on new markers of fatty liver in women with type 2 diabe More
        Introduction: Fatty liver is recognized as a pathophysiological condition in people with type 2 diabetes. The aim of the present study was to investigate the effect of exercise (intermittent and periodic) training on new markers of fatty liver in women with type 2 diabetes in Kashan.Materials and methods: Thirty women with type 2 diabetes were randomly divided into three groups: periodic exercise (n= 10), continuous exercise (n= 10) and control group (n= 10). Experimental groups performed pre-specified exercises for 8 weeks. Blood samples were taken from three groups before and after 8 weeks of exercise protocol. Covariance analysis was used to test the research hypotheses. SPSS software was used for statistical analysis.Findings: The results of the present study showed that LAP and FLI decreased significantly after continuous and intermittent training compared to the control group, although no significant change was observed in the HSI and FSI variables.Conclusion: The results showed that 8 weeks of continuous and intermittent exercise significantly decreased LAP and FLI in women with type 2 diabetes. Therefore, it is recommended to include a weekly exercise program in these patients. Manuscript profile
      • Open Access Article

        3 - The Effect of Eight Weeks of Interval Training with Grape Seed Nanoparticles Supplementation on Bax and Bcl2 Gene Expression in the Heart Tissue of Myocardial Infarction Rats
        Hamid Mohammadi Hosseinabadi Khosro Jalali Dehkordi gholamreza sharifi Zohreh Mazaheri Tirani
        Introduction: The use of exercise training and herbal supplements to treat diseases and metabolic disorders has become common among people. Considering the health-improving effects of aerobic training and grape seed nanoparticles extract, the present study was performed More
        Introduction: The use of exercise training and herbal supplements to treat diseases and metabolic disorders has become common among people. Considering the health-improving effects of aerobic training and grape seed nanoparticles extract, the present study was performed to investigate the effect of eight weeks of aerobic training with grape seed extract supplementation on Bax and Bcl2 gene expression in the heart tissue of rats with myocardial infarction.Materials and methods: In this experimental study, 20 rats were divided into four groups of five animals, including: 1) control, 2) aerobic training, 3) grape extract, and 4) training + grape extract. To investigate the effects of myocardial infarction on the study variables, five healthy rats were placed in the healthy control group. For eight weeks, groups 3 and 4 consumed 150 mg of grape extract daily by gavage. Also, groups 2 and 4 performed aerobic interval training, with 7 interval alternations, each including 4 minutes with an intensity of 80-90% VO2max and 3 minutes with an intensity of 65-75% VO2max. The Kolmogorov- Smirnov and one-way ANOVA with Tukey’s post- hoc tests were used to analyze the findings (P≥0.05).Findings: Induction of myocardial infarction had a significant effect on increasing Bax gene expression and decreasing Bcl2 gene expression in heart tissue (P≥0.001). However, aerobic training along with grape seed nanoparticle extract consumption had a significant effect on reducing Bax gene expression and increasing Bcl2 gene expression in the heart tissue of rats with myocardial infarction (P≥0.01).Conclusion: It seems that aerobic training along with grape extract consumption has more favorable effects on improving Bax and Bcl2 gene levels in myocardial infarction than either alone. Manuscript profile
      • Open Access Article

        4 - The Effect of Swimming Training and Trans-cinnamic Acid on Anxiety, Working Memory and Dark Neuron Density of Rat’s Offspring Hippocampus in Prenatal Seizure Model
        Mohammad Ali Zarei Seyed Ebrahim Hosseini Mohammad Amin Edalatmanesh
        Introduction: Perinatal seizure cause hippocampal neuronal apoptosis by inducing oxidative stress in the fetal central nervous system. This study evaluates the effect of swimming training (ST) and trans-cinnamic acid (CIN) administration during pregnancy on anxiety, cel More
        Introduction: Perinatal seizure cause hippocampal neuronal apoptosis by inducing oxidative stress in the fetal central nervous system. This study evaluates the effect of swimming training (ST) and trans-cinnamic acid (CIN) administration during pregnancy on anxiety, cell damage and density of apoptic neurons in the neonatal hippocampus following penthylentetrazol (PTZ)-induced perinatal seizures. Materials and methods: In this experimental study, neonates from 25 Wistar pregnant rats were randomly divided into 5 healthy control, PTZ+NS, PTZ+CIN, PTZ+ST and PTZ+CIN+ST groups. From embryonic day (ED) 14, the animals were treated with repeated PTZ administration (50 mg / kg, intra- peritoneally) for 5 consecutive days. During pregnancy, moderate intensity swimming (20 min, 3 sessions per week) and CIN gavage (100 mg/kg) were performed daily until term delivery. Anxiety-like behaviors and working memory were assessed with elevated plus maze and Y maze, respectively and dark neurons density was measured in the hippocampus of male neonate at postnatal day (PND) 30. Findings: Significant decrease in alteration behavior and increase in anxiety with high density of dark neuron in different areas of hippocampus were observed in the PTZ+NS group compared to the control group (p ˂ 0.05). On the other hand, in PTZ+CIN+ST group, in comparison with PTZ+NS group, a decrease in anxiety, amelioration of working memory deficit and a decrease in hippocampal dark neuron density were observed (p ˂ 0.05). Conclusion: Interaction of swimming training with trans-cinnamic acid administration ameliorates cognitive-behavioral deficits and cell damage in the hippocampus of rats exposed to maternal seizures. Manuscript profile
      • Open Access Article

        5 - The Effect of Eight-Week Aerobic Training with Garlic Supplementation on Anxiety and Depression in Rats Exposed to WIFI Electromagnetic Radiation
        Amir Omid Asiye Seyyed Maryam Kheirdeh
        Introduction: It appears that electromagnetic radiations around us can lead to psychological disorders. Even though the role of exercise and herbs in improving mental health has been shown, the interactive effect of aerobic training and garlic supplementation on the ner More
        Introduction: It appears that electromagnetic radiations around us can lead to psychological disorders. Even though the role of exercise and herbs in improving mental health has been shown, the interactive effect of aerobic training and garlic supplementation on the nervous system under harmful electromagnetic radiation is still unknown. Therefore, the aim of this study was to investigate the effect of eight weeks of endurance training along with garlic extract consumption on rats exposed to electromagnetic radiation emitted from a WIFI modem.Materials and methods: In this experimental trial, 40 eight-week- male rats weighing 150-200 g were randomly divided into five groups, including: (1) control (C), (2) control + WIFI electromagnetic radiation, (C + WIFI) (3) aerobic training + WIFI electromagnetic radiation (AT + WIFI) (4) garlic extract supplementation + WIFI electromagnetic radiation (GE + WIFI) and (5) aerobic training + garlic extract supplementation + WIFI electromagnetic radiation (AT + GE + WIFI). Groups 2-5 were exposed to 2.45 GHz radiation emitted from a WIFI modem for 1 hour a day for eight weeks. Groups 3 and 5 performed aerobic training for eight weeks, three sessions per week at a rate of 12-18 m / min, and groups 4 and 5 received 800 mg / kg of garlic aqueous extract daily in their drinking water.Findings: Aerobic training and garlic supplementation had a significant effect on reducing depression (P≤0.05) and anxiety (P≤0.05) in rats exposed to WIFI electromagnetic radiation, but garlic supplementation and training had no interactive effect on reducing anxiety and depression in rats (P≥0.05).Conclusion: It seems that the use of either aerobic training or garlic extract supplementation alone has anti-anxiety and anti-depressant effects on rats under WIFI electromagnetic radiation. Manuscript profile
      • Open Access Article

        6 - The Effect of Eight Weeks of Resistance Training on the Quality of Work Life and Body Composition in Female Physicians
        azita bordbar vahid rafiee amin rayat
        Introduction: Quality of work life refers to the satisfaction of employees with different needs through resources, activities and the results of being at work. The aim of this study was to investigate the effect of eight weeks of resistance training on the quality of wo More
        Introduction: Quality of work life refers to the satisfaction of employees with different needs through resources, activities and the results of being at work. The aim of this study was to investigate the effect of eight weeks of resistance training on the quality of work life and body composition in female physicians. Materials and methods: In this quasi-experimental study, 20 female general practitioners referring to Shiraz Guard Sports Club were selected as the statistical sample and were divided into training and control groups. The training group performed resistance training for eight weeks and three sessions per week. Also, the control group had only their daily activities during this period. Before training and 24 hours after the last training session, body composition was measured by the body composition device and quality of work life by the Walton Quality of Life Questionnaire. Shapiro-Wilk, independent and dependent t-tests were used to analyze the findings (P≥0.05). Findings: There were significant differences in changes in total body water (P=0.27), protein mass (P=0.24), mineral mass (P=0.09), net body mass (P=0.97), fat mass (P=0.84) and no quality of work life (P=0.23) was seen in the training and control groups in the post-test compared to the pre-test. Conclusion: It seems that the resistance training protocol of the present study does not have a significant effect on improving the quality of work life and body composition of physicians. Manuscript profile
      • Open Access Article

        7 - The Effect of Eight Weeks of Anaerobic Interval Training on the Body Composition Indices of Inactive Obese Women
        Elham Elahi Mehran Ghahramani Parisa Banaei
        Introduction: In recent years, the prevalence of obesity and overweight among untrained men and women has grown significantly and has now become a serious problem in the world. The aim of this study was to evaluate the effect of eight weeks of anaerobic interval trainin More
        Introduction: In recent years, the prevalence of obesity and overweight among untrained men and women has grown significantly and has now become a serious problem in the world. The aim of this study was to evaluate the effect of eight weeks of anaerobic interval training on body composition indices in inactive obese women. Materials and methods: As an applied research, the present quasi-experimental study with pre-test and post-test design was conducted with two groups of anaerobic interval training and control, in which data were collected through a field study. The statistical sample of the study included 24 obese women over 40 years of age who were assigned into two groups including anaerobic interval training group and control group. Anaerobic interval training was performed for 8 weeks, 5 sessions per week and 25 minutes per session. Before the start of the study and 48 hours after the last training session, body fat percentage, body fat mass, lean body mass and body mass index were measured. Statistical analysis of the findings was performed using independent and dependent samples t-test at a significance level of P <0.05. Findings: Eight weeks of anaerobic interval training has a significant effect on reducing body fat percentage and body mass index as well as increasing lean body mass (P≥0.05). Conclusion: It seems that eight weeks of anaerobic interval training improves the body composition of inactive obese women. Manuscript profile