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        1 - Study Effects Of Hydroalcoholic Extract Of Medicago sativa in the Treatment Of Acetic Acid Induced Gastric Ulcer in Rats
        Mahdi Margani Hamed Alizadeh Sina Aghshahi
        Inroduction and Objective:Peptic ulcer, from histologicalpointisknownasmucosalnecrosisfactor. The purpose of this study was to investigate the effect of Alfalfa hydroalcoholicvegetivearial organs extract on gastric ulcer induced by acetic acid in Rat.Material and Method More
        Inroduction and Objective:Peptic ulcer, from histologicalpointisknownasmucosalnecrosisfactor. The purpose of this study was to investigate the effect of Alfalfa hydroalcoholicvegetivearial organs extract on gastric ulcer induced by acetic acid in Rat.Material and Methods: In this experimental study, 60 wistar rats weighting approximately (200-250g) were randomly divided into 4 groups; control, sham(normal salin), experiment 1 (extract of dose 250 mg/kg body weight) and experiment 2 (extract of dose 500 mg/kg body weight). Rats were deprived of food and then underwent surgeryand gastric wasby injecting60% acetic acid after 4,7,10,14 days gavage, the rats' stomach out and then measuring the wound and fixed with 10% formalin, the passage of the tissue section was stained And the number of neutrophils, macrophages and fibroblasts were counted.Results:Results showed that the hydroalcoholic extract of Alfalfacaused a significant increase in gastric ulcer healing in experimental groups 1 and 2 (PConclusion:Alfalfahydroalcoholic vegetive arial organs extract is effective in the treatment of peptic ulcer induced by acetic acid Manuscript profile
      • Open Access Article

        2 - Study Effects Of Hydroalcoholic Extract Of Medicago sativa in the Treatment Of Acetic Acid Induced Gastric Ulcer in Rats
        Mojdeh Samari Mehdi Rahnema Shahrzad Nasiri Semnani Ali Shahnavaz
        Inroduction and Objective:Peptic ulcer, from histologicalpointisknownasmucosalnecrosisfactor. The purpose of this study was to investigate the effect of Alfalfa hydroalcoholicvegetivearial organs extract on gastric ulcer induced by acetic acid in Rat.Material and Method More
        Inroduction and Objective:Peptic ulcer, from histologicalpointisknownasmucosalnecrosisfactor. The purpose of this study was to investigate the effect of Alfalfa hydroalcoholicvegetivearial organs extract on gastric ulcer induced by acetic acid in Rat.Material and Methods: In this experimental study, 60 wistar rats weighting approximately (200-250g) were randomly divided into 4 groups; control, sham(normal salin), experiment 1 (extract of dose 250 mg/kg body weight) and experiment 2 (extract of dose 500 mg/kg body weight). Rats were deprived of food and then underwent surgeryand gastric wasby injecting60% acetic acid after 4,7,10,14 days gavage, the rats' stomach out and then measuring the wound and fixed with 10% formalin, the passage of the tissue section was stained And the number of neutrophils, macrophages and fibroblasts were counted.Results:Results showed that the hydroalcoholic extract of Alfalfacaused a significant increase in gastric ulcer healing in experimental groups 1 and 2 (PConclusion:Alfalfahydroalcoholic vegetive arial organs extract is effective in the treatment of peptic ulcer induced by acetic acid. Manuscript profile
      • Open Access Article

        3 - The Effect Of Hydro-Alcoholic (Ricinus communis) SeedExtract on Spermatogenesis and Sexual hormones in Mice
        Roya Mohammadi meyabadi Mitra Heidari Nasrabadi Parvin Khodarahmi
        Inroduction and Objective:  The different researches have been done to prevent population.Ricinus communishas different propertiesThis study analyzes the effects of preventing castor's generating.Material and Methods: 21 male mice from NMRI species approximately weighin More
        Inroduction and Objective:  The different researches have been done to prevent population.Ricinus communishas different propertiesThis study analyzes the effects of preventing castor's generating.Material and Methods: 21 male mice from NMRI species approximately weighing 20-30 gr classified into one control group and two experimental groups. Within 30 days, the experimental groups injected as 35 and 45mg/kg body weight by castor's hydro alcoholic extract and normal saline injected to the control group. 10 days after the mice were last injected, samples taken from their blood and generating organs.The serums transmitted into laboratory for the hormones assessments and some 5 micron transversal cuts taken from their testicles, next they were painted and spermcellular classification counted. The sperm maker's diameter pipes and the germinal layer measured by 10X lens and the cells counted by100X lens. All the data were done by ANOVA statistical method and Tukey test with the p≤ 0.05 meaningful level.Results:A meaningful decrease observed in seminiferous tubules diameterpipes in the 45 mg/kg concentration,germinal diameter layer in experimental groups and the number of spermatogony, primary spermatocyte, sperm and leydig in experimental groups in comparison to control group(0.05>p). The percentage of the moving sperms, the percentage of the sperm's genetic substance and the sperms' morphology demonstrated a meaningful reduction in experimental groups and the hormones assesments. Manuscript profile
      • Open Access Article

        4 - The effect of mobile phone waves and using garlic on estrogen, testosterone and dehydroepiandrosterone hormones in rats
        Vahid Hemayatkhah Jahromi mahbobe Parnian
        Introduction: Electromagnetic waves is effect factor on sexual glands and fertility The present study aimed to determine the effect of mobile phone waves and using garlic on sexual hormones in rats. Methods: 28 adult male rats with average weight of 236.5 g were selecte More
        Introduction: Electromagnetic waves is effect factor on sexual glands and fertility The present study aimed to determine the effect of mobile phone waves and using garlic on sexual hormones in rats. Methods: 28 adult male rats with average weight of 236.5 g were selected. Rats were divided into 4 groups of 7. Experimental group A: Receiving 900 MHz microwave waves, experimental group B: receiving 20 ml the extract of cooked garlic, experimental group C: receiving 20 ml the extract of cooked garlic extract with microwave light at wave length 900 MHz, control group: untreated group with normal diet. Then the concentration of sexualhormones were measured. Results: Estrogen and hydroepiandrosterone levels that were exposured to electromagnetic wave were significantly higher in the experimental group than in the control group (P <0.05). The group with using garlic extract and receiving the wave of mobile phone simultaneously, there was a significant increasing in the concentration of estrogen, testosterone and dehydroepiandrosterone comparing to the control group (P <0.05). Conclusion and Discussion: Garlic extract could not offset the damaging effects of sexual hormones in rats were exposed to radiation and use garlic extract simultaneously. Manuscript profile
      • Open Access Article

        5 - The Effects of Desmopressin Acetate during the Prenatal and Neonatal Development of the Hypothalamus-Pituitary-Gonadal Axis on Serum Levels of Sexual Hormones at Puberty in Male Rats
        سید ابراهیم حسینی مختار مختاری گلشید ساکی
        Desmopressin acetate (DA) is one of the synthetic replacements of vasopressin. Considering the possible effects of this medication on the reproductive system, in the present study the effects of this medication during fetal and neonatal development of the hypothalamic p More
        Desmopressin acetate (DA) is one of the synthetic replacements of vasopressin. Considering the possible effects of this medication on the reproductive system, in the present study the effects of this medication during fetal and neonatal development of the hypothalamic pituitary gonadal (HPG) axis on sexual hormones of peripubertal male rat offspring was determined. In this experimental study fifty female and twenty adult male wistar rats were used. after becoming pregnant, females were divided into five groups of ten including the control group (no treatment), Sham group 1 and experimental group 1 which received intraperitoneal injection of distilled water and 6mcg/Kg/day DA, prenatally, and Sham group 2 and experimental group 2 that received nothing, but their offspring received intraperitoneal injection of distilled water and 6mcg/Kg/day DA, neonatally. At ninth weeks after birth, the concentration of sexual hormones was measured by Electrochemiluminescence. The results were statistically analyzed by one-way ANOVA test. The results indicate that the concentration of sexual hormones in prenatally and neonatally treated male rats was not significantly different than the control group. It is suggested that DA doesnandrsquo;t cross the placenta and doesnandrsquo;t interfere with fetal development of HPG axis of male rat offspring. Also, because of the stopped development of leydig cells and its inactivated receptors during neonatal period, the steroidogenesis of leydig cells during pripubertal period wouldnandrsquo;t undergo the effects of DA which was injected at the first week of life. Manuscript profile
      • Open Access Article

        6 - The Effect of Garlic Extract on Sexual Hormones in Heat-stressedFemale Mice
        مهرداد مدرسی مهدی حیدری
        Heat stress is one of the most important environmental pressures especially in tropics which reduce sexual performance by affecting whole vital system. Garlic (Allium sativum) as an effective pharmaceutical plant has been proposed for increasing resistance against stres More
        Heat stress is one of the most important environmental pressures especially in tropics which reduce sexual performance by affecting whole vital system. Garlic (Allium sativum) as an effective pharmaceutical plant has been proposed for increasing resistance against stress. Current research was carried out to study the effects of garlic hydro alcoholic extract on reproductive hormones in female mice under heat stress. Fifty female mice were studied in five groups and ten replications. Experimental treatments were control group (normal situation without receiving extract), 0, 200, 400, and 800 mg/kg of body weight of external for thirty days. Blood samples were taken at the end of experiment period and estrogen, progesterone, FSH and LH hormones were measured. Obtained data were analyzed using SPSS program. Heat stress reduced all sexual hormones significantly (p Manuscript profile