• List of Articles Seminiferous

      • Open Access Article

        1 - Study Effects Of Hydroalcoholic Extract Of Medicago sativa in the Treatment Of Acetic Acid Induced Gastric Ulcer in Rats
        Mahdi Margani Hamed Alizadeh Sina Aghshahi
        Inroduction and Objective:Peptic ulcer, from histologicalpointisknownasmucosalnecrosisfactor. The purpose of this study was to investigate the effect of Alfalfa hydroalcoholicvegetivearial organs extract on gastric ulcer induced by acetic acid in Rat.Material and Method More
        Inroduction and Objective:Peptic ulcer, from histologicalpointisknownasmucosalnecrosisfactor. The purpose of this study was to investigate the effect of Alfalfa hydroalcoholicvegetivearial organs extract on gastric ulcer induced by acetic acid in Rat.Material and Methods: In this experimental study, 60 wistar rats weighting approximately (200-250g) were randomly divided into 4 groups; control, sham(normal salin), experiment 1 (extract of dose 250 mg/kg body weight) and experiment 2 (extract of dose 500 mg/kg body weight). Rats were deprived of food and then underwent surgeryand gastric wasby injecting60% acetic acid after 4,7,10,14 days gavage, the rats' stomach out and then measuring the wound and fixed with 10% formalin, the passage of the tissue section was stained And the number of neutrophils, macrophages and fibroblasts were counted.Results:Results showed that the hydroalcoholic extract of Alfalfacaused a significant increase in gastric ulcer healing in experimental groups 1 and 2 (PConclusion:Alfalfahydroalcoholic vegetive arial organs extract is effective in the treatment of peptic ulcer induced by acetic acid Manuscript profile
      • Open Access Article

        2 - Study Effects Of Hydroalcoholic Extract Of Medicago sativa in the Treatment Of Acetic Acid Induced Gastric Ulcer in Rats
        Mojdeh Samari Mehdi Rahnema Shahrzad Nasiri Semnani Ali Shahnavaz
        Inroduction and Objective:Peptic ulcer, from histologicalpointisknownasmucosalnecrosisfactor. The purpose of this study was to investigate the effect of Alfalfa hydroalcoholicvegetivearial organs extract on gastric ulcer induced by acetic acid in Rat.Material and Method More
        Inroduction and Objective:Peptic ulcer, from histologicalpointisknownasmucosalnecrosisfactor. The purpose of this study was to investigate the effect of Alfalfa hydroalcoholicvegetivearial organs extract on gastric ulcer induced by acetic acid in Rat.Material and Methods: In this experimental study, 60 wistar rats weighting approximately (200-250g) were randomly divided into 4 groups; control, sham(normal salin), experiment 1 (extract of dose 250 mg/kg body weight) and experiment 2 (extract of dose 500 mg/kg body weight). Rats were deprived of food and then underwent surgeryand gastric wasby injecting60% acetic acid after 4,7,10,14 days gavage, the rats' stomach out and then measuring the wound and fixed with 10% formalin, the passage of the tissue section was stained And the number of neutrophils, macrophages and fibroblasts were counted.Results:Results showed that the hydroalcoholic extract of Alfalfacaused a significant increase in gastric ulcer healing in experimental groups 1 and 2 (PConclusion:Alfalfahydroalcoholic vegetive arial organs extract is effective in the treatment of peptic ulcer induced by acetic acid. Manuscript profile
      • Open Access Article

        3 - The Effect Of Hydro-Alcoholic (Ricinus communis) SeedExtract on Spermatogenesis and Sexual hormones in Mice
        Roya Mohammadi meyabadi Mitra Heidari Nasrabadi Parvin Khodarahmi
        Inroduction and Objective:  The different researches have been done to prevent population.Ricinus communishas different propertiesThis study analyzes the effects of preventing castor's generating.Material and Methods: 21 male mice from NMRI species approximately weighin More
        Inroduction and Objective:  The different researches have been done to prevent population.Ricinus communishas different propertiesThis study analyzes the effects of preventing castor's generating.Material and Methods: 21 male mice from NMRI species approximately weighing 20-30 gr classified into one control group and two experimental groups. Within 30 days, the experimental groups injected as 35 and 45mg/kg body weight by castor's hydro alcoholic extract and normal saline injected to the control group. 10 days after the mice were last injected, samples taken from their blood and generating organs.The serums transmitted into laboratory for the hormones assessments and some 5 micron transversal cuts taken from their testicles, next they were painted and spermcellular classification counted. The sperm maker's diameter pipes and the germinal layer measured by 10X lens and the cells counted by100X lens. All the data were done by ANOVA statistical method and Tukey test with the p≤ 0.05 meaningful level.Results:A meaningful decrease observed in seminiferous tubules diameterpipes in the 45 mg/kg concentration,germinal diameter layer in experimental groups and the number of spermatogony, primary spermatocyte, sperm and leydig in experimental groups in comparison to control group(0.05>p). The percentage of the moving sperms, the percentage of the sperm's genetic substance and the sperms' morphology demonstrated a meaningful reduction in experimental groups and the hormones assesments. Manuscript profile
      • Open Access Article

        4 - Stereological study of changes of testicular tissue in Egyptian Fruit bat (Rousettus aegyptiacus) throughout the year
        Farangis Ghassemi Esmat Abas Fard
        Due to importance of bats in ecosystem and the limited information about reproduction of this useful organism, the spermatogenesis of the Egyptian Fruit bat (Rousettus aegyptiacus) was studied stereologically in three seasons, spring to autumn, as the first record. For More
        Due to importance of bats in ecosystem and the limited information about reproduction of this useful organism, the spermatogenesis of the Egyptian Fruit bat (Rousettus aegyptiacus) was studied stereologically in three seasons, spring to autumn, as the first record. For this purpose, 7 male bats were captured by mistnet in Sangtārashan Cave (Fars- Jahrom ), and transferred to the laboratory at the end of every season. After anesthetization and dissection of bats, their testicles were removed and fixed after measuring. The sections (5μm) were prepared from fixed samples and stained. The volume of studied parameters was determined by using Cavallier method, and seminiferous diameters and testicular cells number were measured with stereo Lite software. Obtained data were analyzed by Kruskal–Wallis, and compared by Friedman test. According to obtained results, the testicles were in the scrotum out of the body with significant difference of weight and volume in the left and right testis, and the maximum weight (0.7650± 0.19g) and volume (862± 0.41 mm3) were in spring. The germ cells and many sperm were observed in the lumens in all seasons. The diameter of seminiferous tubule were different (P<0.05) between spring (235/90±1.06 µm) and autumn (227.82±1.29 µm) were observed. Maximum mean number of spermatocyt (294.6×106), sertoli (11.59×106) and lydig (39.30×106) were estimated in spring and the lowest of them in autumn, but the maximum number of spermatid (284.2 ×106) were in autumn. According to these results, the peak of sexual activity of this bat species is in spring and summer. Manuscript profile
      • Open Access Article

        5 - The Effect of Curcumin on Testosterone and Liver Enzyme Levels in Varicocele-induced Rats
        Mohamad Reza Sadraie Marzieh Tavalaee Mohammad Hosein Nasr-Esfahani Mohsen Forouzanfar
        Varicocele is one of the most important causes of infertility in men, which in addition to negatively affecting spermatogenesis, can also affect the endocrine system. The link between varicocele and testosterone production is unclear. The liver is one of the most effect More
        Varicocele is one of the most important causes of infertility in men, which in addition to negatively affecting spermatogenesis, can also affect the endocrine system. The link between varicocele and testosterone production is unclear. The liver is one of the most effective organs in the metabolism of substances and hormones. This study aimed to evaluate serum testosterone levels and their association with liver enzymatic changes. Fifty male Wistar rats were divided into 5 groups, including sham control, varicocele induction, varicocele induction (50 mg/kg curcumin), and varicocele induction (100 mg / kg curcumin). After the treatment period, iron (Fe2 +), testosterone, direct bilirubin, total bilirubin and serum concentrations of ALT, and AST were assessed and liver tissue was isolated and examined. Varicocele caused a significant increase in iron levels (p ≤ 0.05) and a non-significant decrease in testosterone levels (p = 0.242) and total bilirubin (T) (p = 0.639). The treatment resulted in a significant decrease in the levels of iron (p = 0.056) and total bilirubin (p = 0.639), as well as a significant increase in testosterone levels (p < 0.05) compared to the varicocele. While the level of direct bilirubin (p ≥ 0.05) in the varicocele showed a significant increase compared to the sham and control. Using curcumin significantly reduced it compared to the varicocele (p = 0.03). Evaluation of ALT (p = 0.762) and AST (p = 0.367) levels did not show a significant difference among the groups. The levels of iron, testosterone, bilirubin, and liver enzymes are negatively affected by varicocele. Curcumin may lessen the harmful effects of varicocele on biochemical components linked with liver tissue in addition to preventing varicocele damage to testicular tissue. In varicocele rats, greater dosages of curcumin may lower the liver enzyme AST. Manuscript profile
      • Open Access Article

        6 - Comparative Effects of Benzyl Ester and Propylene Glycol Administration on Quantitative Indices of Rat Seminiferous Tubules
        Atarod Sadat Mostafavinia Zahra Nadia Sharifi Mahnaz Nouri Parsa Nazari Fatemeh Mohammadi Parmida Seraj Seyed Mohammad Hossein Noori Mugahi
        According to highlighted role of men in family planning, the use of reversible methods of contraception with no adverse effects on androgen-dependent metabolic reactions is very important. In order to achieve a conductor combination in the designing contraceptive drugs, More
        According to highlighted role of men in family planning, the use of reversible methods of contraception with no adverse effects on androgen-dependent metabolic reactions is very important. In order to achieve a conductor combination in the designing contraceptive drugs, in the study, the effect of two drugs: Propylene glycol and Benzyl Ester on histological parameters of seminiferous tubules was investigated. This study was conducted on the 33 rats Sprague-Dawley with weighing 250-300 gr and least 100 days. Then they were divided into a group containing 13 rats and two groups containing 10 rats and were Received respectively 15 mg/kg of Propylene glycol and Benzyl Ester and Normal Saline as subcutaneous injection daily for 60 days. Next, samples of testicular fixative were stained by the usual method (H&E) and Histological parameters of seminiferous tubules were measured through stereometry and morphometry methods. Reduce the Diameter and Perimeter of seminiferous tubules in the group of Benzyl Ester had significant difference with the two other groups while there was not noticeable difference among the three studied groups in terms of seminiferous tubules number. Benzyl ester was more effective on Histological parameters of seminiferous tubules. Thus, with eliminating the cardiovascular effects and Conservation the contraceptives properties, it can be used as a guide combination. Manuscript profile