List of Articles Irisin

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  1 - The Effect of 16 Weeks of Low Calorie Diet on Irisin Serum Levels and Insulin Resistance Index in Obese Sedentary Women
  A. Ramezankhani R. Sori
  Introduction: Irisin is a new adipokine that is released from membrane protein FNDC5 and has positive effects on metabolism. The aim of this study was to survey the effects of caloric restriction on serum irisin levels and insulin resistance index in obese sedentary wom More

  Introduction: Irisin is a new adipokine that is released from membrane protein FNDC5 and has positive effects on metabolism. The aim of this study was to survey the effects of caloric restriction on serum irisin levels and insulin resistance index in obese sedentary women. Materials and Methods: Twenty women (Mean± SD: 41.40±4.53 years; 76.69±6.14 Kg) who referred to home health of west of Tehran were divided into two groups; caloric restriction group (n=10) and control group (n=10). The calorie restriction group, in the intervention period, received 25% less than the estimated daily energy requirement. Serum irisin, glucose, insulin levels and insulin resistance using HOMA-IR were measured before and after 16 weeks. Results: Weight, BMI (body mass index), WHR (waist to hip ratio), serum irisin, fasting glucose, fasting insulin and HOMA-IR were decreased significantly in the caloric restriction group. Significant correlation were observed between changes of serum irisin levels with changes of body weight, WHR, HOMA-IR, fasting glucose and fasting insulin levels (p<0.05). Conclusion: There is a significant correlation between serum irisin levels with BMI, WHR and HOMA-IR. 16 weeks of caloric restriction is effective in reduction of serum irisin levels and insulin resistance in obese sedentary women. Manuscript profile
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  2 - The Effect of 8 weeks of Concurrent Training on Plasma Concentration of Irisin and BDNF in Overweight Middle-Aged Men
  Zohre Koohkheil Davar Khodadadi Parham Jalali
  The purpose of the present study is to review the effect of 8 weeks of concurrent training on plasma concentration of Irisin and Brain-Derived Neurotrophic Factor (BDNF) in overweight middle-aged men.20 healthy middle-aged men with the average age of 51.3±7.5 wer More

  The purpose of the present study is to review the effect of 8 weeks of concurrent training on plasma concentration of Irisin and Brain-Derived Neurotrophic Factor (BDNF) in overweight middle-aged men.20 healthy middle-aged men with the average age of 51.3±7.5 were randomly chosen and divided into 2 groups of test (10 members) and control (10 members) groups. The participants in the test group took part in 8 weeks of concurrent exercise. The work out plan consisted of 10 minutes of warm-up, 25 minutes of aerobics, 30 minutes of endurance activities, and 5 minutes of cool-down. Blood samples were tested before the test and 48 hours after the last work out session in order to measure Irisin and BDNF levels by ELISA test. For data analysis, t-test was used. The results showed that plasma concentration of Irisin and BDNF levels increased significantly in the test group compared to the pre-test (P≥ 0.001). Also, the comparison between test group and control group in post-test indicated high plasma levels of Irisin and BDNF in the concurrent test group (P≥ 0.001). Furthermore, there was a significantly positive relation between plasma changes of Irisin and BDNF (r-0.569; P≥ 0.01).  It seems that concurrent exercising can positively regulate Irisin and BDNF levels in overweight middle-aged men and thus fight against the harmful effects of aging. Manuscript profile
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  3 - The effects of 8 weeks of high and moderate intensities of interval exercise on irisin and adipolin levels in type 2 diabetic male rats
  Roya Besharati
  The effects of 8 weeks of high and moderate intensities of interval exercise on irisin and adipolin levels in type 2 diabetic male ratsIntroduction: The purpose of this study was to compare the effects of high and moderate intensities of interval exercise on irisin and More

  The effects of 8 weeks of high and moderate intensities of interval exercise on irisin and adipolin levels in type 2 diabetic male ratsIntroduction: The purpose of this study was to compare the effects of high and moderate intensities of interval exercise on irisin and adipolin levels in type 2 diabetic male rats. Material & Methods: Thirty-two male Wistar rats were divided into two groups: healthy and diabetic, and then diabetic rats were randomly divided into three subgroups of diabetic control and two groups HIIT and MIIT so that the present study was performed on four groups (8 groups each). The training was performed in the MIIT with 65-70% and in the HIIT group with 85-90% of the maximum oxygen consumption during eight weeks. 24 hours after the last training session, the mice were removed by intraperitoneal injection of a combination of anesthetic ketamine and xylazine. The levels of irisin and adipolin were measured by the ELISA method. Data were analyzed by one-way ANOVA and Tukey's post hoc test. Results: The results of the post hoc test indicated a significant increase in irisin and adipolin in the high and moderate-intensity interval training groups compared to the control group (p = 0.001). There was no significant difference between high-intensity and moderate-intensity training groups (p = 0.274). Conclusions: moderate and high-intensity interval training lead to a significant increase in irisin and adipolin in diabetic rats.Keywords: Diabetes, Irisin, Adipolin, interval training Manuscript profile
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  4 - The Effects Of 8 Weeks of High and Moderate Intensity Interval Training on Irisin and Adipolin Levels in Type 2 Diabetic Male Rats
  Roya Besharati
  Aim: The purpose of this study was to compare the effects of high and moderate intensity interval training on Irisin and Adipolin levels in type 2 diabetic male rats. Methods: Thirty-two male Wistar rats were divided into two groups: healthy and diabetic, diabetic rats More

  Aim: The purpose of this study was to compare the effects of high and moderate intensity interval training on Irisin and Adipolin levels in type 2 diabetic male rats. Methods: Thirty-two male Wistar rats were divided into two groups: healthy and diabetic, diabetic rats were randomly divided into three subgroups of diabetic control and two HIIT and MIIT groups; so that the present study was performed on four groups (8 per each group). The training was performed with 65-70% and 85-90% of the maximum oxygen consumption in MIIT and HIIT groups, respectively. Twenty-four hours after the last training session, the mice were removed by intraperitoneal injection of a combination of anaesthetic ketamine and xylazine. The levels of Irisin and adipolin were measured by ELISA method. Data were analysed by one-way ANOVA and Tukey's post hoc test. Results: The results of the post hoc test indicated a significant increase in irisin and adipolin in the HIIT and MIIT groups compared to the control group (p = 0.001). There was no significant difference between HIIT and MIIT groups (p = 0.274). Conclusion: HIIT and MIIT could lead to a significant increase in irisin and adipolin in diabetic rats. Keywords: Diabetes, Irisin, Adipolin and interval training. Manuscript profile
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  5 - Effect of aerobic training intensity on irisin in streptozotocin-induced diabetic rats
  Sahar Heidari Mehrzad Moghadasi
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  6 - The Effect of 8-week Resistance Training on Preptin, Irisin and Insulin Resistance in Obese Women
  Elham Zaeimifard Sajad Arshadi Abdol Ali Banaeifar Shahram Soheili
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  7 - An Investigation into Irisin Levels: Acute and Chronic Effects of Combined Training and Its Association with Anthropometric Variables in Overweight Men
  Yazgaldi Nazari Masoud Nikbakht Abdolhamid Habibi
  10.22034/jchr.2017.544180
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  8 - Comparison of the Effect of HIRT and TRT Exercises on Irisin and Insulin Resistance Index in Overweight Men in Hamadan
  majid khanbabaieenava seydvahid fazeliyan salman lotfi
  The aim of this study was to compare the effect of high-intensity resistance training (HIRT) and traditional resistance training (TRT) on serum irisin and insulin resistance index in overweight men in Hamadan. In this study, 36 overweight men with a body mass index More

  The aim of this study was to compare the effect of high-intensity resistance training (HIRT) and traditional resistance training (TRT) on serum irisin and insulin resistance index in overweight men in Hamadan. In this study, 36 overweight men with a body mass index above 24 were selected as a sample and randomly divided into three control groups: HIRT and TRT. Subjects in the TRT training group performed resistance training with an intensity of 70% of one maximal repetition and the HIRT training group performed an eight-week resistance training protocol with an intensity of 85% of a maximal repetition. Before and after exercise, irisin, insulin resistance index Waist period size, fasting glucose, fasting insulin and body mass index were measured, and the results were analyzed using one-way analysis of variance and significant using Tukey post hoc test.The results showed that high-intensity resistance training (HIRT) caused significant changes in irisin (P <0.05) and insulin resistance index (P <0.05), but these changes were not significant in the traditional training group (TRT) (P> 0.05). ).Both training methods caused changes in serum irisin levels and insulin resistance index in overweight men compared to the control group, but high-intensity resistance training had a greater effect on changing serum irisin levels and insulin resistance index in overweight men than traditional exercises. Manuscript profile