The Effect of 8 weeks of Concurrent Training on Plasma Concentration of Irisin and BDNF in Overweight Middle-Aged Men

Subject Areas : Sports Science and Healthy

Zohre  Koohkheil ¹ (Master's Student, Faculty of Physical Education and Sports Sciences, Karaj Branch, Islamic Azad University, Karaj, Iran.)
Davar  Khodadadi ² (Assistant Professor, Department of Physical Education and Sports Sciences, West Tehran Branch, Islamic Azad University, Tehran, Iran)
Parham  Jalali ³ (BA., Department of Physical Education and Sports Sciences, West Tehran Branch, Islamic Azad University, Tehran, Iran.)

Received: 2023-05-30 Accepted : 2023-06-25 Published : 2022-12-22

Keywords: Middle Aged Men, overweight, Irisin, Plasma BDNF.h, Concurrent training,

Abstract :

The purpose of the present study is to review the effect of 8 weeks of concurrent training on plasma concentration of Irisin and Brain-Derived Neurotrophic Factor (BDNF) in overweight middle-aged men.20 healthy middle-aged men with the average age of 51.3±7.5 were randomly chosen and divided into 2 groups of test (10 members) and control (10 members) groups. The participants in the test group took part in 8 weeks of concurrent exercise. The work out plan consisted of 10 minutes of warm-up, 25 minutes of aerobics, 30 minutes of endurance activities, and 5 minutes of cool-down. Blood samples were tested before the test and 48 hours after the last work out session in order to measure Irisin and BDNF levels by ELISA test. For data analysis, t-test was used. The results showed that plasma concentration of Irisin and BDNF levels increased significantly in the test group compared to the pre-test (P≥ 0.001). Also, the comparison between test group and control group in post-test indicated high plasma levels of Irisin and BDNF in the concurrent test group (P≥ 0.001). Furthermore, there was a significantly positive relation between plasma changes of Irisin and BDNF (r-0.569; P≥ 0.01).  It seems that concurrent exercising can positively regulate Irisin and BDNF levels in overweight middle-aged men and thus fight against the harmful effects of aging.

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