List of Articles Copper nanoparticles

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  1 - Antioxidant effect of copper nanoparticles coated with Artemisia annua plant extract in the 2nd degree burns in mice
  فرزانه Tavakoli بهناز Karimi babaahmadi موسی Javdani جهانگیر Kaboutari
  10.30495/jcp.2023.22495
  Burns trigger intricate inflammatory processes and the generation of free radicals. The anti-inflammatory, antioxidant, and antibacterial characteristics of the Artemisia annua plant have a significant potential for enhancing the healing process for wounds. This study e More

  Burns trigger intricate inflammatory processes and the generation of free radicals. The anti-inflammatory, antioxidant, and antibacterial characteristics of the Artemisia annua plant have a significant potential for enhancing the healing process for wounds. This study examines the impact of an Artemisia annua extract-coated copper nanoparticle ointment on the antioxidant enzyme activity in second-degree burns in mice. After the green synthesis of coated copper nanoparticles, 100 male mice were divided into five groups: control without treatment, eucerin ointment group, 0.2% copper nanoparticle ointment, 0.2% copper nanoparticles coated with Artemisia annua extract ointment, and 5% Artemisia annua extract ointment. The activity of antioxidant enzymes and the level of lipid peroxidation in tissue homogenates were measured on days 14, 7, 3, and 21. SOD, CAT, and GPX activities were all significantly higher on day 7 in the coated copper nanoparticle ointment group compared to the control group (P˂0.05). The level of MDA was also significantly lower in the control group on days 7, 14, and 21 (P 0.05). The extract of the medicinal plant Artemisia annua is useful for making and coating copper nanoparticles. In addition to the advantages of plant extract, copper nanoparticles have a synergistic impact that speeds up the healing of second-degree burn wounds in mice by lowering lipid peroxidation in wound tissue and boosting antioxidant activity. Manuscript profile
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  2 - Effects of Nanocoatings Containing Copper on the Microbial and Physical Characteristics of Milk as Compared to Regular Polyethylene Packaging
  S. Ebrahimiasl A. Soltani Chapezad A. Javadi
  Introduction: The application of using nanotechnology in food packaging is mixing nanoparticles with packaging material to prevent bacterial deterioration and loss of nutriants in order to improve the shelf life. The aim of this study is to extend the shelf life of milk More

  Introduction: The application of using nanotechnology in food packaging is mixing nanoparticles with packaging material to prevent bacterial deterioration and loss of nutriants in order to improve the shelf life. The aim of this study is to extend the shelf life of milk by the application of the antibacterial polyethylene packaging that consists of copper nanoparticles. Materials and Methods: Nanocomposite film consisted of copper nanoparticles was prepared by using industrial extruder for milk packaging at 4ºC. Microbial stability, pH variation, thermal stability and nanoparticle release at zero, 7 to 45 days of storing and water vapour permability for the nanocomposite were analyzed in triplicate order. Results: Microbial analysis indicated that the growth rate in nanocomposite consisted of copper nanoparticles decreased significantly by 38 days of storage. pH variations and acid production due to milk deterioration indicated the quality during storage. Thermal analysis of milk after 38 days of packaging in nanocopper packaging confirmed the level of deterioration during storage. The amount of copper released in milk was within permitted level (2.1ppb). SEM and TEM images indicated the presence of copper nanoparticles in polymer base and its hemogeneous distribution in polymer matrix. The application of nanoparticle in milk caused an increase in shelf life. The results showed that by increasing the concentrations of copper nanoparticles, moisture absorption of the film is decreased. Conclusion: The results indicated that synthesized copper/polyethylen composite increased the shelf life of milk during storage. Manuscript profile
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  3 - Antibacterial Activity and Conductivity Properties of Nanocomposites based on Cellulose Acetate Nanofibers and Copper Nanoparticles
  Mohsen Sargordan -Arani Elham Alsadat Hoseini Behrooz Mirza
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  4 - Phytoconstituents of Chromolaena odorata (L.) leaf extract for the synthesis of copper oxide/copper nanoparticles and evaluation of their biological potential in wound healing
  Sobha Kota Pradeep Dumpala Radhika Sajja Ratnakumari Anantha
  10.30495/tpr.2023.1990359.1363
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  5 - Tissue and Molecule Investigation and the Effect of Copper Nanoparticles Synerigm with Antibiotics on Colorectal Cancer Tumors Infected to Kelebsiella pneumonia
  Sedighe Mehrabian Maria Valadbeaigi Shahla Mohammadganji
  Inroduction & Objective: Colorectal is second common type of cancer in the universe. Genetic alteration scope in Colorectal is wide spread and inspections indicates infection to special kind of Kelebsiella pneumoniae bacteria which includes pks genes, can cause Colorect More

  Inroduction & Objective: Colorectal is second common type of cancer in the universe. Genetic alteration scope in Colorectal is wide spread and inspections indicates infection to special kind of Kelebsiella pneumoniae bacteria which includes pks genes, can cause Colorectal cancer. A Kelebsiella bacterium is the reason for infectious diseases with challenging cures. Anti-biotic which are taken to cure (remedy) are of high side effects. This study is designed for the purpose of eliminating drug resistance and making use of low dose antibiotics in specific bacterial infections which makes change possible in intestine cell and incidence of cancer and may help cure or prevention.Material and Methods:In this method the investigation was carried out after supplying copper nanoparticles from Nano Pars Company with scale of 20 nanometer, purity degree of 99.9%, isolation and identification of Kelebsiella bacterium performed using common microbiologic and molecular methods. Kirby and Bauer method used in order to investigate bacterium resistance with different density of copper nanoparticles. The Synergistic effect or anti-biotic was investigated by impregnated anti-biotic discs with highest density of copper nanoparticles which not possess inhibitoringeffect. In this study strains including pks gene, were identified and isolated through PCR, then through different tests antimicrobial effects of copper nanoparticles and antibiotics upon mentioned strains was investigated. Antibiotics resistant to strains were identified. Mentioned bacteria sensitive to copper nanoparticles highest concentrations of copper nanoparticles that was not inhibited, concluded that using the lowest concentration of nanoparticles that demonstrated synergistic effects with antibiotic resistant.Results: The overall result can be used for treatment and prevention using nano biotic. In comparison with copper nanoparticles aforesaid bacteria were sensitive, highest density of copper nanoparticles which had no controlling effect, were selected.Conclusion:General result was that through using lowest density of nanoparticles which the impact of Synergistic with resistant anti-biotic indicated, nano-biotic can be used for curing and prevention. Manuscript profile
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  6 - The Antibiotic Resistance Pattern of Methicillin Resistant Staphylococcus aureus and Antibacterial Effect of Silver and Copper Nanoparticles on that In vitro and Animal model
  Saba Hashemi Rasoul Shokri
  Background & aim: Considering the high resistance to drug in methicillin-resistant Staphylococcus aureus, this study was performed to investigate the effects of silver and copper nanoparticles and their combined effect on the methicillin-resistant Staphylococcus aur More

  Background & aim: Considering the high resistance to drug in methicillin-resistant Staphylococcus aureus, this study was performed to investigate the effects of silver and copper nanoparticles and their combined effect on the methicillin-resistant Staphylococcus aureus in vitro and animal models.Materials & Methods: To determine the most effective antibiotics, disk diffusion method was performed. The microdilution method is used for determination of Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC) of copper and silver nanoparticles and their combination . Then, to examine the effect of nanoparticles and the antibiotic, experiments were performed in the animal models. For this purpose, after intraperitoneal inoculation of bacterial suspension, MBC concertrations obtained from microdilution method were injected to the mice and after the cultivation of spleen, colony count was performed.Results: The most effective antibiotic on bacteria was vancomycin. The MIC of silver and copper nanoparticles, vancomycin, silver and copper nanoparticles, silver nanoparticles-vancomycin and copper nanoparticles- vancomycin were 1250 ppm, 2500 ppm, 78/12, 625 ppm, 35 ppm and 250 ppm respectively. In animal model, the lowest number of colonies is related to silver nanoparticles and then silver nanoparticles-vancomycin.Conclusion: The results show that antimicrobial effect of silver nanoparticles is more than vancomycin and copper nanoparticles. Also the combination of silver and copper nanoparticles increases their antimicrobial strength and the combination of silver and vancomycin after complementary experiments, can be a option for the treatment of infections caused by these bacteria. Manuscript profile
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  7 - Synthesis of Copper Nanoparticles in Aqueous Ambient Using Dismutation Reaction
  Khodarahm Ghandi Yousef Zeraatkish
  10.22034/jna.2014.02.003
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  8 - Synthesis of copper magnetic nanocomposite based on nanofibrillated cellulose and investigation of its catalytic performance in reduction of dyes
  Fatemeh Aliramezani Hannaneh Heidari
  10.30495/jacr.2022.684653
  In this study, nanofibrillated cellulose (NFC) was used as a green and biodegradable material for the synthesis of copper magnetic nanocomposites without the addition of an external reducing agent or toxic solvents. Initially, nanofibrillated cellulose was magnetized fo More

  In this study, nanofibrillated cellulose (NFC) was used as a green and biodegradable material for the synthesis of copper magnetic nanocomposites without the addition of an external reducing agent or toxic solvents. Initially, nanofibrillated cellulose was magnetized for easy separation using iron chlorides in ammonia medium, then used as a substrate and reducing agent for the formation of copper nanoparticles. The structure of the nanocomposite was characterized by various spectroscopic techniques including X‐ray diffraction (XRD), field emission scanning electron microscopy (FE-SEM), Fourier transforms infrared spectroscopy (FT-IR), Energy dispersive spectroscopy (EDS), and Inductively coupled plasma atomic emission spectroscopy (ICP-OES). The effect of nanocomposite drying methods such as freeze-drying and ambient temperature on catalytic activity was also studied. The results showed that the recyclable magnetic nanocatalyst Fe3O4@NFC/Cu in comparison with other reported catalysts had significant catalytic activity in degradation of three organic dyes (methyl orange, methylene blue, and 4-nitrophenol) with rate constants of 35.1×10-2 s-1 1.48×10-2 s-1 and 5.41×10-2 s-1, respectively. Also, this catalyst was recovered and used 4 times without significant loss of activity. Manuscript profile
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  9 - Biosynthesis of copper nanoparticles by Stenotrophomonas maltophilia
  Zahra Amirpoor Monir Doudi Gholam Reza Amiri
  Background & Objectives: Heavy metals are environmentally sustainable and durable pollutants that have become a world problem. As microorganisms show high resistance to heavy metals and can purify the environment and produce nanoparticles, the present study was desi More

  Background & Objectives: Heavy metals are environmentally sustainable and durable pollutants that have become a world problem. As microorganisms show high resistance to heavy metals and can purify the environment and produce nanoparticles, the present study was designed to produce copper nanoparticles from copper-resistant bacteria isolated from wastewater of two copper workshops in Isfahan. Materials & Methods: In this cross-sectional study,  wastewater samples were collected from two copper workshops in Isfahan. The physicochemical factors of the wastewater, the minimum inhibitory concentration of bacteria (MIC) to copper and their resistance to several antibiotics were investigated. Morphological, biochemical and molecular identification tests were carried out on samples. Then the biomass of copper-resistant bacteria was added to the copper sulfate pentahydrate stock (CuSO4.5H2O) and the results were evaluated by Ultraviolet-Visible spectrophotometer (UV-VIS), X-ray diffraction (XRD) and Transient Electron Microscopy (TEM). Results: Among the studied bacteria, the Bacillus toyonensis strain NE2 with the MIC of 3.5 mM and Arthrobacteragilis NE1 with MIC of 4 mM from copper workshop 2 and Stenotrophomonas maltophilia strain 5633 with the MIC of  6 mM from copper workshop 1 were isolated. Among these isolates, only S. maltophilia strain 5633 was able to synthesize copper nanoparticles. Peaks created in the range of 250-430 nm confirmed the presence of  Copper (Cu) and Copper Oxide (CuO) particles. Conclusion: The findings of this study showed that the isolated bacteria could be a good candidate to remove copper from wastewater and to biosynthesize copper nanoparticle.  Manuscript profile
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  10 - Study of Drought Tolerance of Wheat Inoculated with Mycorrhiza Fungi and its Interaction with Copper Nanoparticles
  ّfatemeh taheri hesari hossain zahedi Alireza Eivazi younes sharghi Akbar Alipoor
  A split-split plot field experiment using the randomized complete block design with three replicates was carried out to investigate drought tolerance of wheat inoculated with mycorrhiza fungi and its interaction with copper nanoparticles. The factors included two irriga More

  A split-split plot field experiment using the randomized complete block design with three replicates was carried out to investigate drought tolerance of wheat inoculated with mycorrhiza fungi and its interaction with copper nanoparticles. The factors included two irrigation levels (optimum irrigation and deficit irrigation), two levels of fungal symbiosis (with or without a symbiotic relationship), and three spray concentrations of copper oxide nanoparticles (50, 250, and 450 ppm).The results of ANOVA revealed that Analysis of variance showed that proline content and spike/m2 were significant in irrigation regime, mycorrhiza, foliar application, and all the interaction effects of double and triple factors.The effect of irrigation regime, mycorrhiza and foliar application of copper nano oxide was effective on grain yield, but the effects and interactions of irrigation regime×foliar application, mycorrhiza×foliar application and irrigation regime×mycorrhiza×foliar application have no significate effect on that characteristic;Comparison of mean traits showed that the maximum number of spikes/m2 in mycorrhizal fungi application with50ppm copper nano oxide foliar application in optimum irrigation was780numbers.The highest hectolitre weight of wheat was related to triple interactions,optimum irrigation with fungus and foliar application of450ppm copper nano oxide that was not statistically significant effect with triple interactions,optimum irrigation without fungus and foliar application of 250ppm copper nano oxide.Maximum proline content was obtained in non-mycorrhizal fungi treatment with50ppm foliar spray under deficit irrigation (23.8mg/g fresh weight) which was statistically significant at least at5%level with other treatments. The highest grain yield (309.61g/m2) belonged to optimum irrigation treatment and minimum grain yield was observed in severe deficit irrigation. Manuscript profile