This study aims to report on the literature related to the barriers to ICT (Information Communications Technology) integration into ESP (English for Specific Purposes) instruction that hinder promoting ESP instruction through this integration. The literature review has also shed light upon ways of addressing these barriers. To meet this end, the paper begins with discussing a review of some of the important Iranian and international studies on barriers to ICT integration in ESP instruction and then the paper highlights a number of first-order, second-order barriers, and ways of addressing them to help in promoting and changing traditional ESP instruction and materials. It is suggested that this review could be useful for those who make decisions about the ESP courses, for ESP material developers, and for ESP teachers to change from traditional ESP instruction, which is teacher-centered and text-based, to a new ESP instruction through ICT integration. This review has also implications for practice. Change is mostly challenging; reporting a review of previous studies on barriers to ICT integration at the tertiary level and proposing ways of addressing them may help defeat the barriers and may enhance acceptance of new ESP teaching and learning methods. Manuscript profile