Variation bioactive metabolites of Tanacetum parthenium L. in two regions in North of Iran.
Subject Areas : Geneticمعصومه Mazandarani 1 , gh Naseri 2 , mb Rezaei 3
1 - Dep. Biology, Islamic Azad Univ, Gorgan Branch, Gorgan, Iran
2 - Dep. Biology, Islamic Azad Univ, Gorgan Branch, Gorgan, Iran
3 - Forest and Rangeland Institute, Tehran, Iran
Keywords: Golestan province, flavonoid, alkaloid, Essential oil, Tanacetum parthenium L,
Abstract :
Tanacetum parthenium L. is one of the most important medicinal herbs, has been used by the rural people of Golestan province for sedative pain, fever, headache, arthritis, asthma, toothache and menstrual disorders.Variation in bioactive components of Tanacetum parthenium L. were studied and compared for their essential oil, flavonoids and alkaloids of different parts of plant in two geographical regions of this province. Results showed T. parthenium which originated from 2200m produced the highest essential oils, flavonoids and alkaloids, especially in leaves but with low quality and quantities and reduced in flowers. Further more stem have not any bioactive components in two regions.
Awang, D.V., (1998). Prescribing therapeutic feverfew Tanacetum parthenium (L.) Schultz Bip., syn. (Chrysanthemum parthenium (L.) Bernh.), Integrative Medicine 1 (1), pp. 11–13.
Baser K.H., Demirci, C.B., Tabanca, N., Özek, T., and Goren, N. (2001) Composition of the essential oils of Tanacetum armenum (DC.) Schultz Bip., T. balsamita L., T. chiliophyllum (Fisch. & Mey) Schultz Bip. var. chiliophyllum and T. haradjani (Rech. Fil.) Grierson and the enantiomeric distribution of camphor and carvone, Flav. Fragr. J. 16, pp. 195–200.
Changqing, W., Feng, C., Xi, W., Hyun-Jin, K., Guo-qing, H., Vivian, H.Z., George, H. (2006). Antioxidant constituents in feverfew (Tanacetum parthenium) extract and their chromatographic quantification. Available online at www.sciencedirect.com. Food Chemistry 96 (2006) 220-227.
Goren, N., Demirci, B., and Baser, K.H.C. (2001). Composition of the essential oils of Tanacetum spp, From Turkey. Flav. Fragr. J. 16, pp. 191–194.
Groenewegen, W.A., Knight, D.W., and Heptinstall, S. (1992). Progress in the medicinal chemistry of the herb feverfew. In G.P. Ellis & D.K. Luscombe (Eds.). Progress in medicinal chemistry. pp. 217-238.
Hendriks, H., Bos, R., and Woerdenbag, J., (1996). The essential oil of Tanacetum parthenium (L.) Schultz-Bip, Flav. Fragr. J. 11, pp. 367–371.
Hethelyi, E., Tetenyi, P., Danos, B., and Koczka, I. (1999). Phytochemical and antimicrobial studies on the essential oils of the Tanacetum vulgare clones by gas chromatography/mass spectrometry, Herba Hung 30, pp. 82–90.
Holopainen, M., and Kauppinen, V. (1989). Antimicrobial activity of different chemotypes of Finnish tansy, Planta Med. 55 (1989), p. 103.
Hulten, E., (1968). Flora of Alaska and Neighboring Territories. A Manual of the Vascular Plants, Stanford University Press, Stanford CA, 1008 p.
Hussey, J., (1974). Hussey, Some useful plants of early New England, Econ. Bot. 28, pp. 311–337.
Jaime, A., Teixeira, S., (2004). Minning the essential oils of the Anthemidaea, A.J. Biotech. 3, (12). 706-720.
Jain, N.K. and Kulkarni, B. (1999). Antinociceptive and anti-inflammatory effects of Tanacetum parthenium L. extract in mice and rats, J. Ethnopharmacol. 68, pp. 251–259.
Keskitalo, M., Pehu, E., and Simon, J.E (2001). Variation in volatile compounds from tansy (Tanacetum vulgare L.) related to genetic and morphological differences of genotypes, Biochem. Syst. Ecol. 29, pp. 267–285.
Long, C., Sauleau, P., David, B., Lavaud, C., Cassabois, V., Ausseil, F., and Massiot, G. (2003). Bioactive flavonoids of Tanacetum parthenium revisited, Phytochemistry 64, pp. 567–569.
Mashhadian, N.V., Rakhshandeh, H., (2005). Antibacterial and antifungal effects of nigella sativa extracts against S.aureus, P. aero ginosa and C. albicans. Pakistan Journal of medical science, 21(1): 47-52.
McVean, M., Xiao, H., Isobe, K-I., & Pelling, J.C. (2000). Increase in wild-type p53 stability and transactivational activity by the chemopreventive agent apigenin in keratinocytes. Carcinogenesis, 21(4), 633-639.
Mittra, S., Datta, A., Singh, S.K., & Singh, A. (2000). 5-Hydroxy-tryptamine-inhibiting property of feverfew: role of parthenolide content. Acta pharmacola gica Sinica, 21, 1106-1114.
Nori-Shargh, D., Norouzi-Arasi, H,. Mirza, M., Jaimand, K., and Mohammadi, S. (1999). Chemical composition of the essential oil of Tanacetum polycephalum (Schultz Bip. ssp. heterophyllum), Flav. Fragr. J. 14, pp. 105–106.
Orav, A., Raal, A., Arak, E., and Kailas, T. (2006). Composition of essential oil of Artemisia absinthium L. of different geographical origin. Estinian Acad. Sci. Chem. 55, 3, 155-165.
Pedrialla, P., & Skibsted, L.H. (2002). Antioxidant synergy and regeneration effect of quercetin, (-)-epicatechin, and (+) catechin on α-tocopherol in homogeneous solutions of peroxidating methyl linoleate. Journal of Agricultural and Food chemistry, 50, 7138-7144.
Schearer, W.R., (1984). Components of oil of tansy (Tanacetum vulgare) that repel Colorado potato beetles (Leptinotarsa decemlineara), J. Nat. Prod. 47, pp. 964–969.
Shiravastara, R., Pechadre, J.C., John, G.W., (2006). Tanacetum parthenium and Salix alba combination in migraine prophylaxis, J. Pub med, 26(5), 287-295.
Sultana, S., and Saleem, M. (2004). Salix caprea inhibits skin carcinogenesis in ''murine Skin: inhibition ofoxidative stress, ornithine decarboxylase activity and DNA synthesis, Journal of Ethnopharmacology. pp. 267-276.
Theresa, H, Piela, S., and Xiufang, L. (2001). Feverfew extracts and the sesquiterpene lactone parthenolide inhibit intercellular adhesion molecule-1 expression in human synovial fibroblasts. Cellular immunology 209, 89-96.
Tiuman, T.S., Nakamura, T.U., and Nakamura, C.V., 2005. Antileshmanial activity of parthenolide, a sesquiterpene lactone isolated from T. parthenium, antimicrobial agent and Chemotherapy. (49) 176-182.
Tyler, V.E. (1993). The honest herbal: a sensible guide to the use of herbs and related remedies (third ed.), Pharmacey.tiealProducts Press, Binghamton. pp. 133-134.
Wen R. You, S.Y. Lee, C.H. Song and D.G. Kirn. (2002). Oxidative stress-mediated apoptosis. The anticancer effect of the sesquiterpene lactone parthenolide, Journal of Biological Chemistry 277(41), pp. 38954-38964.
Williams, C., Harborne, J.B. Geiger, H. Robin, J. and Hoult, S. (2003). The flavonoids of Tanacetum parthenium and T. vulgare and their anti-inflammatory properties, Phytochemistry 51, pp. 417–423.
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Awang, D.V., (1998). Prescribing therapeutic feverfew Tanacetum parthenium (L.) Schultz Bip., syn. (Chrysanthemum parthenium (L.) Bernh.), Integrative Medicine 1 (1), pp. 11–13.
Baser K.H., Demirci, C.B., Tabanca, N., Özek, T., and Goren, N. (2001) Composition of the essential oils of Tanacetum armenum (DC.) Schultz Bip., T. balsamita L., T. chiliophyllum (Fisch. & Mey) Schultz Bip. var. chiliophyllum and T. haradjani (Rech. Fil.) Grierson and the enantiomeric distribution of camphor and carvone, Flav. Fragr. J. 16, pp. 195–200.
Changqing, W., Feng, C., Xi, W., Hyun-Jin, K., Guo-qing, H., Vivian, H.Z., George, H. (2006). Antioxidant constituents in feverfew (Tanacetum parthenium) extract and their chromatographic quantification. Available online at www.sciencedirect.com. Food Chemistry 96 (2006) 220-227.
Goren, N., Demirci, B., and Baser, K.H.C. (2001). Composition of the essential oils of Tanacetum spp, From Turkey. Flav. Fragr. J. 16, pp. 191–194.
Groenewegen, W.A., Knight, D.W., and Heptinstall, S. (1992). Progress in the medicinal chemistry of the herb feverfew. In G.P. Ellis & D.K. Luscombe (Eds.). Progress in medicinal chemistry. pp. 217-238.
Hendriks, H., Bos, R., and Woerdenbag, J., (1996). The essential oil of Tanacetum parthenium (L.) Schultz-Bip, Flav. Fragr. J. 11, pp. 367–371.
Hethelyi, E., Tetenyi, P., Danos, B., and Koczka, I. (1999). Phytochemical and antimicrobial studies on the essential oils of the Tanacetum vulgare clones by gas chromatography/mass spectrometry, Herba Hung 30, pp. 82–90.
Holopainen, M., and Kauppinen, V. (1989). Antimicrobial activity of different chemotypes of Finnish tansy, Planta Med. 55 (1989), p. 103.
Hulten, E., (1968). Flora of Alaska and Neighboring Territories. A Manual of the Vascular Plants, Stanford University Press, Stanford CA, 1008 p.
Hussey, J., (1974). Hussey, Some useful plants of early New England, Econ. Bot. 28, pp. 311–337.
Jaime, A., Teixeira, S., (2004). Minning the essential oils of the Anthemidaea, A.J. Biotech. 3, (12). 706-720.
Jain, N.K. and Kulkarni, B. (1999). Antinociceptive and anti-inflammatory effects of Tanacetum parthenium L. extract in mice and rats, J. Ethnopharmacol. 68, pp. 251–259.
Keskitalo, M., Pehu, E., and Simon, J.E (2001). Variation in volatile compounds from tansy (Tanacetum vulgare L.) related to genetic and morphological differences of genotypes, Biochem. Syst. Ecol. 29, pp. 267–285.
Long, C., Sauleau, P., David, B., Lavaud, C., Cassabois, V., Ausseil, F., and Massiot, G. (2003). Bioactive flavonoids of Tanacetum parthenium revisited, Phytochemistry 64, pp. 567–569.
Mashhadian, N.V., Rakhshandeh, H., (2005). Antibacterial and antifungal effects of nigella sativa extracts against S.aureus, P. aero ginosa and C. albicans. Pakistan Journal of medical science, 21(1): 47-52.
McVean, M., Xiao, H., Isobe, K-I., & Pelling, J.C. (2000). Increase in wild-type p53 stability and transactivational activity by the chemopreventive agent apigenin in keratinocytes. Carcinogenesis, 21(4), 633-639.
Mittra, S., Datta, A., Singh, S.K., & Singh, A. (2000). 5-Hydroxy-tryptamine-inhibiting property of feverfew: role of parthenolide content. Acta pharmacola gica Sinica, 21, 1106-1114.
Nori-Shargh, D., Norouzi-Arasi, H,. Mirza, M., Jaimand, K., and Mohammadi, S. (1999). Chemical composition of the essential oil of Tanacetum polycephalum (Schultz Bip. ssp. heterophyllum), Flav. Fragr. J. 14, pp. 105–106.
Orav, A., Raal, A., Arak, E., and Kailas, T. (2006). Composition of essential oil of Artemisia absinthium L. of different geographical origin. Estinian Acad. Sci. Chem. 55, 3, 155-165.
Pedrialla, P., & Skibsted, L.H. (2002). Antioxidant synergy and regeneration effect of quercetin, (-)-epicatechin, and (+) catechin on α-tocopherol in homogeneous solutions of peroxidating methyl linoleate. Journal of Agricultural and Food chemistry, 50, 7138-7144.
Schearer, W.R., (1984). Components of oil of tansy (Tanacetum vulgare) that repel Colorado potato beetles (Leptinotarsa decemlineara), J. Nat. Prod. 47, pp. 964–969.
Shiravastara, R., Pechadre, J.C., John, G.W., (2006). Tanacetum parthenium and Salix alba combination in migraine prophylaxis, J. Pub med, 26(5), 287-295.
Sultana, S., and Saleem, M. (2004). Salix caprea inhibits skin carcinogenesis in ''murine Skin: inhibition ofoxidative stress, ornithine decarboxylase activity and DNA synthesis, Journal of Ethnopharmacology. pp. 267-276.
Theresa, H, Piela, S., and Xiufang, L. (2001). Feverfew extracts and the sesquiterpene lactone parthenolide inhibit intercellular adhesion molecule-1 expression in human synovial fibroblasts. Cellular immunology 209, 89-96.
Tiuman, T.S., Nakamura, T.U., and Nakamura, C.V., 2005. Antileshmanial activity of parthenolide, a sesquiterpene lactone isolated from T. parthenium, antimicrobial agent and Chemotherapy. (49) 176-182.
Tyler, V.E. (1993). The honest herbal: a sensible guide to the use of herbs and related remedies (third ed.), Pharmacey.tiealProducts Press, Binghamton. pp. 133-134.
Wen R. You, S.Y. Lee, C.H. Song and D.G. Kirn. (2002). Oxidative stress-mediated apoptosis. The anticancer effect of the sesquiterpene lactone parthenolide, Journal of Biological Chemistry 277(41), pp. 38954-38964.
Williams, C., Harborne, J.B. Geiger, H. Robin, J. and Hoult, S. (2003). The flavonoids of Tanacetum parthenium and T. vulgare and their anti-inflammatory properties, Phytochemistry 51, pp. 417–423.
