The Effect of Six Weeks Aerobic Training and Cinnamon Extract on IL_1β Gene Expression in Liver Tissue of Male Feeded by High Fat Diet

Subject Areas : Journal of Animal Biology

Alireza Rostamian ¹ , Nematolah Nemati ² , Tahereh Bagher pour ³

1 - Department of Education and Sports Sciences, Damghan Branch, Islamic Azad University, Damghan, Iran
2 - Department of Education and Sports Sciences, Damghan Branch, Islamic Azad University, Damghan, Iran
3 - Department of Education and Sports Sciences, Damghan Branch, Islamic Azad University, Damghan, Iran

Received: 2020-08-11 Accepted : 2020-10-28 Published : 2022-02-20

Keywords: Exercise, Obesity, Cinnamon, High-fat diet, Beta-interleukin,

Abstract :

In obese people, the expression level of interleukin is one beta higher, so that the expression level of interleukin 1 beta is directly related to the level of body mass index and fat mass. This study aimed to determine the effects of six weeks of aerobic exercise, consumption of cinnamon extract and high fat diet on the expression of 1 beta interleukin gene in liver tissue of male rats fed a high fat diet using two-month-old male Wistar rats. Fifty two-month-old male rats were divided into five control groups: high-fat diet, cinnamon extract, and high-fat diet, aerobic training and high-fat diet, and aerobic training and cinnamon extract and high-fat diet after two weeks of control. Cinnamon extract at a rate of 200 mg per kg of body weight and emulsion of high-fat food in excess of water and normal diet of rodents daily at a rate of 1.5 mg per kg of body weight for six weeks by gavage. The training group participated in an aerobic exercise program on a treadmill five days a week for six weeks. The mean of research variables among groups (except the control group) was compared with one-way variance analysis and Bonferroni tests to determine the differences among groups. The mean of research variables between each group was compared with the control group to determine the differences within the group by one-sample t-test at the significant level of p 05 0.05. There was a significant difference between body weight and liver tissue weight in the post-test between all groups. The difference among the mean variables of one beta interleukin in the liver tissue of male rats fed a high-fat diet after six weeks of aerobic exercise, consumption of cinnamon extract, and high-fat diet was significant. Therefore, it seems that the effects of high fat diet, high fat diet and aerobic exercise, high fat diet, and cinnamon and high-fat diet, and aerobic exercise and cinnamon on the interleukin variable of one beta in liver tissue are significant and significant.

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